MX2019012657A - Inhibidores de tirosina cinasa de bruton. - Google Patents

Inhibidores de tirosina cinasa de bruton.

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Publication number
MX2019012657A
MX2019012657A MX2019012657A MX2019012657A MX2019012657A MX 2019012657 A MX2019012657 A MX 2019012657A MX 2019012657 A MX2019012657 A MX 2019012657A MX 2019012657 A MX2019012657 A MX 2019012657A MX 2019012657 A MX2019012657 A MX 2019012657A
Authority
MX
Mexico
Prior art keywords
disclosed
inhibitors
bruton
tyrosine kinase
compounds
Prior art date
Application number
MX2019012657A
Other languages
English (en)
Inventor
Verner Erik
Honigberg Lee
Pan Zhengying
Original Assignee
Pharmacyclics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39225888&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2019012657(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacyclics Llc filed Critical Pharmacyclics Llc
Publication of MX2019012657A publication Critical patent/MX2019012657A/es

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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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Abstract

La presente invención se refiere a compuestos que forman enlaces covalentes con la tirosina cinasa de Bruton (Btk); también se describen inhibidores irreversibles de Btk; se describen métodos para la preparación de los compuestos; también se describen composiciones farmacéuticas que incluyen los compuestos; se describen métodos para usar los inhibidores de Btk, solos o en combinación con otros agentes terapéuticos, para el tratamiento de enfermedades o condiciones autoinmunes, enfermedades o condiciones heteroinmunes, cáncer, que incluye linfoma y enfermedades o condiciones inflamatorias.
MX2019012657A 2006-09-22 2009-03-20 Inhibidores de tirosina cinasa de bruton. MX2019012657A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82672006P 2006-09-22 2006-09-22
US82859006P 2006-10-06 2006-10-06

Publications (1)

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MX2019012657A true MX2019012657A (es) 2019-12-11

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Family Applications (3)

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MX2009003122A MX2009003122A (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de bruton.
MX2012014021A MX347525B (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de bruton.
MX2019012657A MX2019012657A (es) 2006-09-22 2009-03-20 Inhibidores de tirosina cinasa de bruton.

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MX2009003122A MX2009003122A (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de bruton.
MX2012014021A MX347525B (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de bruton.

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EP (11) EP2526933B1 (es)
JP (4) JP4934197B2 (es)
KR (4) KR101315610B1 (es)
CN (4) CN101805341B (es)
AT (1) ATE531263T1 (es)
AU (2) AU2006348662B8 (es)
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SI (8) SI2530083T1 (es)
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BRPI0714963A2 (pt) * 2006-08-16 2013-07-30 Novartis Ag processo de fabricaÇço de dispersÕes sàlidas de compostos terapÊuticos altamente cristalinos
SI2530083T1 (sl) 2006-09-22 2016-09-30 Pharmacyclics Llc Inhibitorji Bruton tirozin kinaze
ES2403546T3 (es) * 2006-11-03 2013-05-20 Pharmacyclics, Inc. Sonda de actividad de la tirosina-cinasa de Bruton y procedimiento de utilización
US8809273B2 (en) * 2007-03-28 2014-08-19 Pharmacyclics, Inc. Inhibitors of Bruton's tyrosine kinase
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