LUC00011I2 - - Google Patents

Info

Publication number
LUC00011I2
LUC00011I2 LU00011C LUC00011C LUC00011I2 LU C00011 I2 LUC00011 I2 LU C00011I2 LU 00011 C LU00011 C LU 00011C LU C00011 C LUC00011 C LU C00011C LU C00011 I2 LUC00011 I2 LU C00011I2
Authority
LU
Luxembourg
Prior art keywords
disclosed
compounds
conditions
btk
methods
Prior art date
Application number
LU00011C
Other languages
English (en)
Original Assignee
Pharmacyclics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39225888&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LUC00011(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacyclics Llc filed Critical Pharmacyclics Llc
Publication of LUC00011I1 publication Critical patent/LUC00011I1/fr
Publication of LUC00011I2 publication Critical patent/LUC00011I2/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
LU00011C 2006-09-22 2017-03-30 LUC00011I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82672006P 2006-09-22 2006-09-22
US82859006P 2006-10-06 2006-10-06
EP06850039.6A EP2081435B1 (fr) 2006-09-22 2006-12-28 Inhibiteurs de la tyrosine kinase de bruton

Publications (2)

Publication Number Publication Date
LUC00011I1 LUC00011I1 (fr) 2017-04-06
LUC00011I2 true LUC00011I2 (fr) 2017-05-30

Family

ID=39225888

Family Applications (3)

Application Number Title Priority Date Filing Date
LU92662C LU92692I2 (fr) 2006-09-22 2015-04-07 Ibrutinib, ou un sel pharmaceutiquement acceptablede celui-ci
LU93321C LU93321I2 (fr) 2006-09-22 2016-11-23 Ibrutinib, ou un sel pharmaceutiquement acceptable de celui-ci
LU00011C LUC00011I2 (fr) 2006-09-22 2017-03-30

Family Applications Before (2)

Application Number Title Priority Date Filing Date
LU92662C LU92692I2 (fr) 2006-09-22 2015-04-07 Ibrutinib, ou un sel pharmaceutiquement acceptablede celui-ci
LU93321C LU93321I2 (fr) 2006-09-22 2016-11-23 Ibrutinib, ou un sel pharmaceutiquement acceptable de celui-ci

Country Status (28)

Country Link
US (48) US7514444B2 (fr)
EP (11) EP2526933B1 (fr)
JP (4) JP4934197B2 (fr)
KR (4) KR101315610B1 (fr)
CN (4) CN101805341B (fr)
AT (1) ATE531263T1 (fr)
AU (2) AU2006348662B8 (fr)
BR (2) BRPI0622054B8 (fr)
CA (3) CA2663116C (fr)
CY (11) CY1112513T1 (fr)
DK (7) DK2526934T3 (fr)
EA (3) EA018573B1 (fr)
ES (8) ES2564647T3 (fr)
FR (1) FR15C0029I2 (fr)
HK (3) HK1140107A1 (fr)
HU (10) HUE031334T2 (fr)
IL (1) IL197550A0 (fr)
LT (7) LT2529621T (fr)
LU (3) LU92692I2 (fr)
MX (3) MX2009003122A (fr)
NL (1) NL300728I1 (fr)
NZ (3) NZ595230A (fr)
PL (8) PL2530083T3 (fr)
PT (7) PT2526933E (fr)
SG (2) SG166093A1 (fr)
SI (8) SI2530083T1 (fr)
WO (1) WO2008039218A2 (fr)
ZA (4) ZA200901784B (fr)

Families Citing this family (512)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005230818B2 (en) 2004-04-02 2010-11-25 Osi Pharmaceuticals, Inc. 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors
EP1906950A4 (fr) * 2005-06-21 2008-09-24 Infinity Discovery Inc Formulations d'ansamycine et leurs procedes d'utilisation
EP2027087A2 (fr) * 2006-05-18 2009-02-25 MannKind Corporation Inhibiteurs de kinases intracellulaires
BRPI0714963A2 (pt) * 2006-08-16 2013-07-30 Novartis Ag processo de fabricaÇço de dispersÕes sàlidas de compostos terapÊuticos altamente cristalinos
SI2530083T1 (sl) 2006-09-22 2016-09-30 Pharmacyclics Llc Inhibitorji Bruton tirozin kinaze
ES2403546T3 (es) * 2006-11-03 2013-05-20 Pharmacyclics, Inc. Sonda de actividad de la tirosina-cinasa de Bruton y procedimiento de utilización
US8809273B2 (en) * 2007-03-28 2014-08-19 Pharmacyclics, Inc. Inhibitors of Bruton's tyrosine kinase
ES2562215T3 (es) 2007-03-28 2016-03-03 Pharmacyclics Llc Inhibidores de la tirosina quinasa de Bruton
US20080255080A1 (en) * 2007-04-12 2008-10-16 Wright James L Hydroquinone Ansamycin Formulations
US7989465B2 (en) * 2007-10-19 2011-08-02 Avila Therapeutics, Inc. 4,6-disubstituted pyrimidines useful as kinase inhibitors
TWI552752B (zh) * 2007-10-19 2016-10-11 賽基艾維洛米斯研究股份有限公司 雜芳基化合物及其用途
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