GB201309085D0 - Compounds - Google Patents
CompoundsInfo
- Publication number
- GB201309085D0 GB201309085D0 GBGB1309085.7A GB201309085A GB201309085D0 GB 201309085 D0 GB201309085 D0 GB 201309085D0 GB 201309085 A GB201309085 A GB 201309085A GB 201309085 D0 GB201309085 D0 GB 201309085D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1309085.7A GB201309085D0 (en) | 2013-05-20 | 2013-05-20 | Compounds |
PCT/GB2014/051542 WO2014188173A1 (en) | 2013-05-20 | 2014-05-20 | Pyrazolopyrimidine derivatives useful as inhibitors of bruton's tyrosine kinase |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1309085.7A GB201309085D0 (en) | 2013-05-20 | 2013-05-20 | Compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
GB201309085D0 true GB201309085D0 (en) | 2013-07-03 |
Family
ID=48747060
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB1309085.7A Ceased GB201309085D0 (en) | 2013-05-20 | 2013-05-20 | Compounds |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB201309085D0 (en) |
WO (1) | WO2014188173A1 (en) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201410430D0 (en) * | 2014-06-11 | 2014-07-23 | Redx Pharma Ltd | Compounds |
CN107207519B (en) * | 2015-02-12 | 2019-11-08 | 正大天晴药业集团股份有限公司 | Yi Bu replaces the preparation method of Buddhist nun |
MA41828A (en) * | 2015-03-27 | 2018-01-30 | Pharmacyclics Llc | CO-CRYSTALS OF A TYROSINE KINASE INHIBITOR FROM BRUTON |
CN106146511A (en) * | 2015-04-03 | 2016-11-23 | 安润医药科技(苏州)有限公司 | Pyrazolopyrimidine derivative, preparation method, pharmaceutical composition and purposes |
WO2016154998A1 (en) * | 2015-04-03 | 2016-10-06 | 安润医药科技(苏州)有限公司 | Pyrazolopyrimidine derivative, manufacturing method, pharmaceutical composition, and use thereof |
CN105777759B (en) * | 2016-04-29 | 2018-01-26 | 杭州和正医药有限公司 | A kind of bruton's tyrosine kinase inhibitor |
CN104844609B (en) * | 2015-05-12 | 2016-07-13 | 杭州和正医药有限公司 | The irreversible bruton's tyrosine kinase inhibitor of dibit point |
EP4116303A1 (en) * | 2015-09-16 | 2023-01-11 | Loxo Oncology, Inc. | Pyrazolopyrimidine derivatives as btk inhibitors for the treatment of cancer |
CR20180367A (en) | 2015-12-16 | 2018-11-12 | Loxo Oncology Inc [ | USEFUL COMPOUNDS AS KINASE INHIBITORS |
KR102547188B1 (en) * | 2015-12-23 | 2023-06-26 | 아르퀼 인코포레이티드 | Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of use thereof |
US9630968B1 (en) | 2015-12-23 | 2017-04-25 | Arqule, Inc. | Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of use thereof |
CN106928231B (en) * | 2015-12-31 | 2021-06-01 | 合肥中科普瑞昇生物医药科技有限公司 | Novel EGFR wild type and mutant kinase inhibitors |
CA3011201C (en) | 2016-01-15 | 2020-09-22 | Pfizer Inc. | 6,7,8,9-tetrahydro-5h-pyrido[2,3-d]azepine dopamine d3 ligands |
CN108602834B (en) * | 2016-02-05 | 2021-01-08 | 北京盛诺基医药科技股份有限公司 | Bruton's tyrosine kinase inhibitor |
EP3433246B1 (en) | 2016-03-24 | 2022-05-04 | Mission Therapeutics Limited | 1-cyano-pyrrolidine derivatives as dbu inhibitors |
WO2018002958A1 (en) | 2016-06-30 | 2018-01-04 | Sun Pharma Advanced Research Company Limited | Novel hydrazide containing compounds as btk inhibitors |
CN106146518A (en) * | 2016-06-30 | 2016-11-23 | 苏州爱玛特生物科技有限公司 | A kind of bruton's tyrosine kinase inhibitor intermediate and preparation method thereof |
KR20190035925A (en) | 2016-08-24 | 2019-04-03 | 아르퀼 인코포레이티드 | Amino-pyrrolopyrimidine compounds and methods for their use |
GB201616511D0 (en) | 2016-09-29 | 2016-11-16 | Mission Therapeutics Limited | Novel compounds |
GB201616627D0 (en) | 2016-09-30 | 2016-11-16 | Mission Therapeutics Limited | Novel compounds |
CN108069974B (en) * | 2016-11-15 | 2019-12-10 | 杭州和正医药有限公司 | Selective Bruton tyrosine kinase inhibitor and application thereof |
CN109369654A (en) * | 2018-11-20 | 2019-02-22 | 山东大学 | 1,3- bis- substituted-4-amino Pyrazolopyrimidines and its preparation method and application |
WO2021038540A1 (en) | 2019-08-31 | 2021-03-04 | Sun Pharma Advanced Research Company Limited | Cycloalkylidene carboxylic acids and derivatives as btk inhibitors |
JP7011638B2 (en) * | 2019-12-16 | 2022-02-10 | アークル インコーポレイテッド | Tetrahydropyranylamino-pyrrolopyrimidinone and how to use it |
CN113214265B (en) * | 2020-01-21 | 2023-07-07 | 江苏先声药业有限公司 | Pyrimidine five-membered ring compound |
RU2747991C1 (en) * | 2020-02-18 | 2021-05-18 | Аркьюл, Инк. | Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of its use |
US20230145305A1 (en) * | 2020-03-12 | 2023-05-11 | Fochon Biosciences, Ltd. | Compounds useful as kinase inhibitors |
WO2022140246A1 (en) | 2020-12-21 | 2022-06-30 | Hangzhou Jijing Pharmaceutical Technology Limited | Methods and compounds for targeted autophagy |
WO2022213932A1 (en) * | 2021-04-06 | 2022-10-13 | 广州必贝特医药股份有限公司 | Pyrrolopyrimidinone compound and application thereof |
CN114761410B (en) * | 2021-04-06 | 2023-08-25 | 广州必贝特医药股份有限公司 | Pyrrolopyrimidinone compounds and application thereof |
CN115894500A (en) * | 2022-11-02 | 2023-04-04 | 中国药科大学 | Compound serving as BTK kinase inhibitor and preparation method and application thereof |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUE031334T2 (en) | 2006-09-22 | 2017-07-28 | Pharmacyclics Llc | Inhibitors of bruton's tyrosine kinase |
US8987233B2 (en) | 2006-11-03 | 2015-03-24 | Pharmacyclics, Inc. | Bruton's tyrosine kinase activity probe and method of using |
SG10202107066WA (en) | 2007-03-28 | 2021-07-29 | Pharmacyclics Llc | Inhibitors of bruton's tyrosine kinase |
US8338439B2 (en) | 2008-06-27 | 2012-12-25 | Celgene Avilomics Research, Inc. | 2,4-disubstituted pyrimidines useful as kinase inhibitors |
RU2536584C2 (en) | 2008-06-27 | 2014-12-27 | Авила Терапьютикс, Инк. | Heteroaryl compounds and using them |
US8426428B2 (en) | 2008-12-05 | 2013-04-23 | Principia Biopharma, Inc. | EGFR kinase knockdown via electrophilically enhanced inhibitors |
US7718662B1 (en) | 2009-10-12 | 2010-05-18 | Pharmacyclics, Inc. | Pyrazolo-pyrimidine inhibitors of bruton's tyrosine kinase |
CN107898791A (en) | 2010-06-03 | 2018-04-13 | 药品循环有限责任公司 | The application of bruton's tyrosine kinase (BTK) inhibitor |
CA2836410C (en) | 2011-05-17 | 2019-08-20 | Principia Biopharma Inc. | Tyrosine kinase inhibitors |
KR102052670B1 (en) | 2011-05-17 | 2019-12-06 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | Kinase inhibitors |
KR20140048968A (en) | 2011-07-13 | 2014-04-24 | 파마시클릭스, 인코포레이티드 | Inhibitors of bruton's tyrosine kinase |
US8377946B1 (en) * | 2011-12-30 | 2013-02-19 | Pharmacyclics, Inc. | Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors |
-
2013
- 2013-05-20 GB GBGB1309085.7A patent/GB201309085D0/en not_active Ceased
-
2014
- 2014-05-20 WO PCT/GB2014/051542 patent/WO2014188173A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2014188173A1 (en) | 2014-11-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AT | Applications terminated before publication under section 16(1) |