BR112014029718A2 - inibidores da proteína quinase - Google Patents

inibidores da proteína quinase

Info

Publication number: BR112014029718A2
Authority: BR; Brazil
Prior art keywords: protein kinase; kinase inhibitors; inhibitors; protein; kinase
Prior art date: 2012-05-31

Application number

BR112014029718A

Other languages

English (en)

Inventor

Laurent Alain

B Jaquith James

Rose Yannick

Original Assignee

Pharmascience Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-05-31

Filing date

2013-05-28

Publication date

2017-06-27

2012-05-31 Priority claimed from CA2779184A external-priority patent/CA2779184A1/en

2013-04-17 Priority claimed from CA2813299A external-priority patent/CA2813299A1/en

2013-05-28 Application filed by Pharmascience Inc filed Critical Pharmascience Inc

2017-06-27 Publication of BR112014029718A2 publication Critical patent/BR112014029718A2/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled

BR112014029718A 2012-05-31 2013-05-28 inibidores da proteína quinase BR112014029718A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
CA2779184A CA2779184A1 (en)	2012-05-31	2012-05-31	Protein kinase inhibitors
CA2813299A CA2813299A1 (en)	2013-04-17	2013-04-17	Protein kinase inhibitors
PCT/CA2013/000513 WO2013177668A1 (en)	2012-05-31	2013-05-28	Protein kinase inhibitors

Publications (1)

Publication Number	Publication Date
BR112014029718A2 true BR112014029718A2 (pt)	2017-06-27

Family

ID=49672221

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR112014029718A BR112014029718A2 (pt)	2012-05-31	2013-05-28	inibidores da proteína quinase

Country Status (11)

Country	Link
US (1)	US9796716B2 (pt)
EP (1)	EP2855484A4 (pt)
JP (1)	JP6175495B2 (pt)
KR (2)	KR101972990B1 (pt)
CN (1)	CN104379586B (pt)
BR (1)	BR112014029718A2 (pt)
CA (1)	CA2874211A1 (pt)
HK (1)	HK1208460A1 (pt)
IN (1)	IN2014MN02338A (pt)
RU (1)	RU2678767C2 (pt)
WO (1)	WO2013177668A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2833867A1 (en) *	2013-11-21	2015-05-21	Pharmascience Inc.	Protein kinase inhibitors
CA2834528A1 (en) *	2013-11-26	2015-05-26	Pharmascience Inc.	Protein kinase inhibitors
CN106573001B (zh) *	2014-07-07	2019-01-29	江苏恒瑞医药股份有限公司	作为蛋白激酶抑制剂的氨基哒嗪酮化合物
GB201508747D0 (en) *	2015-05-21	2015-07-01	Univ Edinburgh	Compounds
CA3025813A1 (en) *	2015-05-27	2016-12-01	Gb005, Inc.	Inhibitors of the tec kinase enzyme family
CN108290850A (zh) *	2015-12-07	2018-07-17	Dic株式会社	聚合性化合物的制造方法
WO2017134685A2 (en) *	2016-02-02	2017-08-10	Sun Pharma Advanced Research Company Limited	Novel hydrazino compounds as btk inhibitors
CN109369654A (zh) *	2018-11-20	2019-02-22	山东大学	1，3-二取代-4-氨基吡唑并嘧啶类化合物及其制备方法和应用
CN111454268B (zh) *	2019-01-18	2023-09-08	明慧医药（上海）有限公司	作为布鲁顿酪氨酸激酶抑制剂的环状分子
WO2023083373A1 (zh) *	2021-11-15	2023-05-19	微境生物医药科技(上海)有限公司	作为Src抑制剂的化合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TR200201506T2 (tr)	1999-09-17	2002-10-21	Abbott Gmbh & Co. Kg	Terapötik maddeler olarak kinaz inhibitörleri
US6921763B2 (en) *	1999-09-17	2005-07-26	Abbott Laboratories	Pyrazolopyrimidines as therapeutic agents
DK1212327T3 (da) *	1999-09-17	2003-12-15	Abbott Gmbh & Co Kg	Pyrazolopyrimidiner som terapeutiske midler
CA2363274A1 (en) *	1999-12-27	2001-07-05	Japan Tobacco Inc.	Fused-ring compounds and use thereof as drugs for hepatitis c
AUPR392301A0 (en)	2001-03-23	2001-04-26	University Of Newcastle Research Associates Limited, The	Protein phosphatase inhibitors
CA2450777C (en) *	2001-08-10	2013-04-09	Novartis Ag	Use of c-src inhibitors alone or in combination with sti571 for the treatment of leukaemia
KR101315610B1 (ko) *	2006-09-22	2013-10-10	파마시클릭스, 인코포레이티드	브루톤 티로신 키나제 억제제
CA2874756C (en) *	2007-03-28	2018-05-29	Pharmacyclics, Inc.	Inhibitors of bruton's tyrosine kinase
US7718662B1 (en) *	2009-10-12	2010-05-18	Pharmacyclics, Inc.	Pyrazolo-pyrimidine inhibitors of bruton's tyrosine kinase
CN102656141B (zh) *	2009-10-13	2016-04-06	利亘制药公司	模拟造血生长因子的小分子化合物及其用途
CN105408334B (zh) *	2013-05-21	2017-10-10	江苏迈度药物研发有限公司	作为激酶抑制剂的取代的吡唑并嘧啶类化合物
CN103787839B (zh)	2014-01-21	2015-12-02	苏州昊帆生物科技有限公司	合成2,3,4,5,6-五氟苯酚的方法

2013
- 2013-05-28 JP JP2015514295A patent/JP6175495B2/ja not_active Expired - Fee Related
- 2013-05-28 IN IN2338MUN2014 patent/IN2014MN02338A/en unknown
- 2013-05-28 CA CA2874211A patent/CA2874211A1/en not_active Abandoned
- 2013-05-28 RU RU2014145285A patent/RU2678767C2/ru not_active IP Right Cessation
- 2013-05-28 KR KR1020147036372A patent/KR101972990B1/ko active IP Right Grant
- 2013-05-28 KR KR1020197011438A patent/KR20190043648A/ko not_active Application Discontinuation
- 2013-05-28 EP EP13796590.1A patent/EP2855484A4/en not_active Withdrawn
- 2013-05-28 BR BR112014029718A patent/BR112014029718A2/pt not_active Application Discontinuation
- 2013-05-28 US US14/404,497 patent/US9796716B2/en not_active Expired - Fee Related
- 2013-05-28 WO PCT/CA2013/000513 patent/WO2013177668A1/en active Application Filing
- 2013-05-28 CN CN201380028248.2A patent/CN104379586B/zh not_active Expired - Fee Related
2015
- 2015-09-18 HK HK15109229.7A patent/HK1208460A1/xx unknown

Also Published As

Publication number	Publication date
JP2015518009A (ja)	2015-06-25
RU2678767C2 (ru)	2019-02-01
WO2013177668A1 (en)	2013-12-05
IN2014MN02338A (pt)	2015-08-14
EP2855484A1 (en)	2015-04-08
RU2014145285A (ru)	2016-07-20
CA2874211A1 (en)	2013-12-05
US20150191473A1 (en)	2015-07-09
US9796716B2 (en)	2017-10-24
KR101972990B1 (ko)	2019-04-26
CN104379586A (zh)	2015-02-25
HK1208460A1 (en)	2016-03-04
KR20150015527A (ko)	2015-02-10
KR20190043648A (ko)	2019-04-26
CN104379586B (zh)	2018-01-16
EP2855484A4 (en)	2015-12-16
JP6175495B2 (ja)	2017-08-02

Legal Events

Date	Code	Title	Description
2018-03-06	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2018-03-13	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2018-03-20	B06I	Publication of requirement cancelled [chapter 6.9 patent gazette]	Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.
2020-02-27	B25A	Requested transfer of rights approved	Owner name: GB005, INC. (US)
2020-10-20	B07E	Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
2020-11-24	B06U	Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
2021-03-09	B11B	Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements

Publication	Publication Date	Title
NL301178I2 (nl)	2024-04-25	Pegcetacoplan
CO6950481A2 (es)	2014-05-20	Inhibidores de proteínas quinasas
HK1215577A1 (zh)	2016-09-02	蛋白激酶抑制劑
HK1217198A1 (zh)	2016-12-30	蛋白激酶抑制劑
CO6970602A2 (es)	2014-06-13	Inhibidores de quinasa
DK2903618T3 (da)	2022-08-22	Rho-kinase-inhibitorer
DK2710007T3 (da)	2020-01-27	Kinasehæmmere
DK2895484T3 (da)	2022-05-09	Glucosylceramidsynthase-inhibitorer
DK2841428T3 (da)	2018-12-10	Dna-pk-inhibitorer
SMT201600114B (it)	2016-08-31	Inibitori di beta-secretasi
DK3527563T3 (da)	2021-12-06	Dna-pk-inhibitorer
DK3409278T3 (da)	2020-11-09	Heterocykliske proteinkinaseinhibitorer
DK2917210T3 (da)	2019-05-27	Alk kinase-inhibitorer
BR112014033056A2 (pt)	2017-06-27	inibidores da proteína quinase
HK1218119A1 (zh)	2017-02-03	蛋白激酶抑制劑
BR112014029718A2 (pt)	2017-06-27	inibidores da proteína quinase
HK1205507A1 (en)	2015-12-18	Protein kinase inhibitors
CO6990735A2 (es)	2014-07-10	Inhibidores de pirazina cinasa
BR112015005361A2 (pt)	2017-07-04	inibidores de tirosina quinase de bruton
BR112015002078A2 (pt)	2017-07-04	inibidores antibacteriais de proteína quinase
BR112014001977A2 (pt)	2017-02-21	inibidores seletivos de proteína quinase
DE112013001038A5 (de)	2015-03-26	Kugel-Schaft-Verbindung
CO6821937A2 (es)	2013-12-31	Nuevos inhibidores de cinasa de proteína de indolinona
TH1401002448B (th)	2016-05-10	สารยับยั้ง dpp-4
UA25179S (uk)	2013-07-25	Шафа