PL2235064T3 - Sposób otrzymywania cząsteczek przeciwciał z heterodimerycznymi fc z zastosowaniem kierujących efektów elektrostatycznych - Google Patents

Sposób otrzymywania cząsteczek przeciwciał z heterodimerycznymi fc z zastosowaniem kierujących efektów elektrostatycznych

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Publication number
PL2235064T3
PL2235064T3 PL09700643T PL09700643T PL2235064T3 PL 2235064 T3 PL2235064 T3 PL 2235064T3 PL 09700643 T PL09700643 T PL 09700643T PL 09700643 T PL09700643 T PL 09700643T PL 2235064 T3 PL2235064 T3 PL 2235064T3
Authority
PL
Poland
Prior art keywords
making antibody
electrostatic steering
steering effects
heterodimeric molecules
heterodimeric
Prior art date
Application number
PL09700643T
Other languages
English (en)
Inventor
Gunasekaran Kannan
Michael Wittekind
Wei Yan
Martin Pentony
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of PL2235064T3 publication Critical patent/PL2235064T3/pl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/526CH3 domain
PL09700643T 2008-01-07 2009-01-06 Sposób otrzymywania cząsteczek przeciwciał z heterodimerycznymi fc z zastosowaniem kierujących efektów elektrostatycznych PL2235064T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1956908P 2008-01-07 2008-01-07
US12030508P 2008-12-05 2008-12-05
PCT/US2009/000071 WO2009089004A1 (en) 2008-01-07 2009-01-06 Method for making antibody fc-heterodimeric molecules using electrostatic steering effects
EP09700643.1A EP2235064B1 (en) 2008-01-07 2009-01-06 Method for making antibody fc-heterodimeric molecules using electrostatic steering effects

Publications (1)

Publication Number Publication Date
PL2235064T3 true PL2235064T3 (pl) 2016-06-30

Family

ID=40578139

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09700643T PL2235064T3 (pl) 2008-01-07 2009-01-06 Sposób otrzymywania cząsteczek przeciwciał z heterodimerycznymi fc z zastosowaniem kierujących efektów elektrostatycznych

Country Status (14)

Country Link
US (2) US8592562B2 (pl)
EP (3) EP3663318A1 (pl)
JP (3) JP6157046B2 (pl)
AU (1) AU2009204501B2 (pl)
CA (1) CA2709847C (pl)
CY (1) CY1117162T1 (pl)
DK (1) DK2235064T3 (pl)
ES (2) ES2774337T3 (pl)
HU (1) HUE028536T2 (pl)
MX (1) MX350962B (pl)
PL (1) PL2235064T3 (pl)
PT (1) PT2235064E (pl)
SI (1) SI2235064T1 (pl)
WO (1) WO2009089004A1 (pl)

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