JOP20200096A1 - جزيئات جسم مضاد لـ tim-3 واستخداماتها - Google Patents

جزيئات جسم مضاد لـ tim-3 واستخداماتها

Info

Publication number
JOP20200096A1
JOP20200096A1 JOP/2020/0096A JOP20200096A JOP20200096A1 JO P20200096 A1 JOP20200096 A1 JO P20200096A1 JO P20200096 A JOP20200096 A JO P20200096A JO P20200096 A1 JOP20200096 A1 JO P20200096A1
Authority
JO
Jordan
Prior art keywords
tim
antibody molecules
cancerous
disorders
treat
Prior art date
Application number
JOP/2020/0096A
Other languages
English (en)
Inventor
A Blattler Walter
Pietzonka Thomas
H Dekruyff Rosemarie
S Harris Alan
T Umetsu Dale
A Taraszka John
J Hicklin Daniel
Brannetti Barbara
Huber Thomas
James Freeman Gordon
Xu Fangmin
Anne Sabatos-Peyton Catherine
Hu Tiancen
Vasquez Maximiliano
Marie Mataraza Jennifer
Original Assignee
Children’S Medical Center Corp
Dana Farber Cancer Inst Inc
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52478098&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JOP20200096(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Children’S Medical Center Corp, Dana Farber Cancer Inst Inc, Novartis Ag filed Critical Children’S Medical Center Corp
Publication of JOP20200096A1 publication Critical patent/JOP20200096A1/ar

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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

تم الكشف عن جزيئات جسم مضاد ترتبط بشكل خاص بـ TIM-3 . يمكن استخدام جزيئات الجسم المضاد لـ TIM-3 لمعالجة، الوقاية و/أو التشخيص المناعي، لسرطان، أو ظروف مُعدية و/أو اضطرابات.
JOP/2020/0096A 2014-01-31 2014-01-31 جزيئات جسم مضاد لـ tim-3 واستخداماتها JOP20200096A1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461934469P 2014-01-31 2014-01-31
US201462094912P 2014-12-19 2014-12-19

Publications (1)

Publication Number Publication Date
JOP20200096A1 true JOP20200096A1 (ar) 2017-06-16

Family

ID=52478098

Family Applications (2)

Application Number Title Priority Date Filing Date
JOP/2020/0096A JOP20200096A1 (ar) 2014-01-31 2014-01-31 جزيئات جسم مضاد لـ tim-3 واستخداماتها
JOP/2015/0017A JO3567B1 (ar) 2014-01-31 2015-02-01 جزيئات جسم مضاد لـ tim-3 واستخداماتها

Family Applications After (1)

Application Number Title Priority Date Filing Date
JOP/2015/0017A JO3567B1 (ar) 2014-01-31 2015-02-01 جزيئات جسم مضاد لـ tim-3 واستخداماتها

Country Status (35)

Country Link
US (6) US9605070B2 (ar)
EP (3) EP3560959B1 (ar)
JP (3) JP6539667B2 (ar)
KR (2) KR20220028145A (ar)
CN (2) CN106132991B (ar)
AU (2) AU2015210750B2 (ar)
BR (1) BR112016016436A2 (ar)
CA (1) CA2936863A1 (ar)
CL (1) CL2016001716A1 (ar)
CR (1) CR20160347A (ar)
CU (1) CU24427B1 (ar)
CY (1) CY1121893T1 (ar)
DK (1) DK3099717T3 (ar)
EA (1) EA201691556A1 (ar)
EC (1) ECSP16070447A (ar)
ES (1) ES2732901T3 (ar)
HR (1) HRP20191083T1 (ar)
HU (1) HUE045065T2 (ar)
IL (1) IL246693B2 (ar)
JO (2) JOP20200096A1 (ar)
LT (1) LT3099717T (ar)
ME (1) ME03489B (ar)
MX (2) MX2016009961A (ar)
MY (1) MY187296A (ar)
NZ (2) NZ761188A (ar)
PE (1) PE20170330A1 (ar)
PH (1) PH12016501482A1 (ar)
PL (1) PL3099717T3 (ar)
PT (1) PT3099717T (ar)
RS (1) RS59065B1 (ar)
SG (1) SG11201605627TA (ar)
SI (1) SI3099717T1 (ar)
TW (2) TWI686406B (ar)
UY (1) UY35973A (ar)
WO (1) WO2015117002A1 (ar)

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