FR901228A
(fr)
|
1943-01-16 |
1945-07-20 |
Deutsche Edelstahlwerke Ag |
Système d'aimant à entrefer annulaire
|
US2779780A
(en)
|
1955-03-01 |
1957-01-29 |
Du Pont |
1, 4-diamino-2, 3-dicyano-1, 4-bis (substituted mercapto) butadienes and their preparation
|
US4261989A
(en)
|
1979-02-19 |
1981-04-14 |
Kaken Chemical Co. Ltd. |
Geldanamycin derivatives and antitumor drug
|
US4433059A
(en)
|
1981-09-08 |
1984-02-21 |
Ortho Diagnostic Systems Inc. |
Double antibody conjugate
|
US4444878A
(en)
|
1981-12-21 |
1984-04-24 |
Boston Biomedical Research Institute, Inc. |
Bispecific antibody determinants
|
US4851332A
(en)
|
1985-04-01 |
1989-07-25 |
Sloan-Kettering Institute For Cancer Research |
Choriocarcinoma monoclonal antibodies and antibody panels
|
US5869620A
(en)
|
1986-09-02 |
1999-02-09 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
US5114946A
(en)
|
1987-06-12 |
1992-05-19 |
American Cyanamid Company |
Transdermal delivery of pharmaceuticals
|
US4818541A
(en)
|
1987-08-19 |
1989-04-04 |
Schering Corporation |
Transdermal delivery of enantiomers of phenylpropanolamine
|
JPH021556A
(ja)
|
1988-06-09 |
1990-01-05 |
Snow Brand Milk Prod Co Ltd |
ハイブリッド抗体及びその作製方法
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
AU6290090A
(en)
|
1989-08-29 |
1991-04-08 |
University Of Southampton |
Bi-or trispecific (fab)3 or (fab)4 conjugates
|
US5273743A
(en)
|
1990-03-09 |
1993-12-28 |
Hybritech Incorporated |
Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent
|
GB9012995D0
(en)
|
1990-06-11 |
1990-08-01 |
Celltech Ltd |
Multivalent antigen-binding proteins
|
US5582996A
(en)
|
1990-12-04 |
1996-12-10 |
The Wistar Institute Of Anatomy & Biology |
Bifunctional antibodies and method of preparing same
|
DE4118120A1
(de)
|
1991-06-03 |
1992-12-10 |
Behringwerke Ag |
Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung
|
US6511663B1
(en)
|
1991-06-11 |
2003-01-28 |
Celltech R&D Limited |
Tri- and tetra-valent monospecific antigen-binding proteins
|
US5637481A
(en)
|
1993-02-01 |
1997-06-10 |
Bristol-Myers Squibb Company |
Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
|
CA2078539C
(en)
|
1991-09-18 |
2005-08-02 |
Kenya Shitara |
Process for producing humanized chimera antibody
|
US5932448A
(en)
|
1991-11-29 |
1999-08-03 |
Protein Design Labs., Inc. |
Bispecific antibody heterodimers
|
CZ287296B6
(en)
|
1992-01-23 |
2000-10-11 |
Merck Patent Gmbh |
Antibody construct and structural kit for selective preparation thereof
|
EP0625200B1
(en)
|
1992-02-06 |
2005-05-11 |
Chiron Corporation |
Biosynthetic binding protein for cancer marker
|
US5646253A
(en)
|
1994-03-08 |
1997-07-08 |
Memorial Sloan-Kettering Cancer Center |
Recombinant human anti-LK26 antibodies
|
ATE165113T1
(de)
|
1992-05-08 |
1998-05-15 |
Creative Biomolecules Inc |
Mehrwertige chimäre proteine anologe und verfahren zu deren anwendungen
|
US6005079A
(en)
|
1992-08-21 |
1999-12-21 |
Vrije Universiteit Brussels |
Immunoglobulins devoid of light chains
|
US7196170B2
(en)
|
1992-09-14 |
2007-03-27 |
The General Hospital Corporation |
Aiolos, Helios, Daedalos and Ikaros: genes, polypeptides, regulatory elements and uses thereof
|
EP0672068A4
(en)
|
1992-09-25 |
1997-02-26 |
Commw Scient Ind Res Org |
TARGET MOLECULES BINDING POLYPEPTIDES.
|
GB9221657D0
(en)
|
1992-10-15 |
1992-11-25 |
Scotgen Ltd |
Recombinant bispecific antibodies
|
US5262564A
(en)
|
1992-10-30 |
1993-11-16 |
Octamer, Inc. |
Sulfinic acid adducts of organo nitroso compounds useful as retroviral inactivating agents anti-retroviral agents and anti-tumor agents
|
WO1994009817A1
(en)
|
1992-11-04 |
1994-05-11 |
City Of Hope |
Novel antibody construct
|
GB9323648D0
(en)
|
1992-11-23 |
1994-01-05 |
Zeneca Ltd |
Proteins
|
ATE199392T1
(de)
|
1992-12-04 |
2001-03-15 |
Medical Res Council |
Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung
|
US6476198B1
(en)
|
1993-07-13 |
2002-11-05 |
The Scripps Research Institute |
Multispecific and multivalent antigen-binding polypeptide molecules
|
US5635602A
(en)
|
1993-08-13 |
1997-06-03 |
The Regents Of The University Of California |
Design and synthesis of bispecific DNA-antibody conjugates
|
WO1995009917A1
(en)
|
1993-10-07 |
1995-04-13 |
The Regents Of The University Of California |
Genetically engineered bispecific tetravalent antibodies
|
EP0679660A4
(en)
|
1993-11-16 |
2000-08-16 |
Pola Chem Ind Inc |
MONOCLONAL ANTIBODY AGAINST HUMAN TYROSINASE
|
US5635388A
(en)
|
1994-04-04 |
1997-06-03 |
Genentech, Inc. |
Agonist antibodies against the flk2/flt3 receptor and uses thereof
|
EP1630229B1
(en)
|
1994-04-22 |
2013-04-03 |
THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services |
Melanoma antigens
|
US5786464C1
(en)
|
1994-09-19 |
2012-04-24 |
Gen Hospital Corp |
Overexpression of mammalian and viral proteins
|
JP3659261B2
(ja)
|
1994-10-20 |
2005-06-15 |
モルフォシス・アクチェンゲゼルシャフト |
組換体タンパク質の多機能性複合体への標的化ヘテロ結合
|
CA2210620C
(en)
|
1995-01-18 |
2004-06-22 |
Boehringer Mannheim Gmbh |
Anti-cd 30 antibodies preventing proteolytic cleavage and release of membrane-bound cd 30 antigen
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
CA2222055A1
(en)
|
1995-05-23 |
1996-11-28 |
Morphosys Gesellschaft Fur Proteinoptimierung Mbh |
Multimeric proteins
|
BR9606706A
(pt)
|
1995-10-16 |
1999-04-06 |
Unilever Nv |
Análogo de fragmento de anticorpo biespecífico ou bivalente uso processo para produzir o mesmo
|
DE69726404T2
(de)
|
1996-01-05 |
2004-09-09 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Mesothelinantigen, verfahren und testsatz zur targetierung
|
DE19608769C1
(de)
|
1996-03-07 |
1997-04-10 |
Univ Eberhard Karls |
Antikörper BV10A4H2
|
ES2225961T3
(es)
|
1996-04-04 |
2005-03-16 |
Unilever N.V. |
Proteina de union a antigeno multivalente y multiespecifica.
|
US6114148C1
(en)
|
1996-09-20 |
2012-05-01 |
Gen Hospital Corp |
High level expression of proteins
|
DE69703121D1
(de)
|
1996-10-25 |
2000-10-19 |
Us Health |
Verfahren und zusammensetzungen zur verhinderung von entzündungen und angiogenese enthaltend säugetieren cd97 alpha untereinheit
|
JP2002505574A
(ja)
|
1997-04-30 |
2002-02-19 |
エンゾン,インコーポレイテッド |
ポリアルキレンオキシド修飾された単鎖ポリペプチド
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
US20030207346A1
(en)
|
1997-05-02 |
2003-11-06 |
William R. Arathoon |
Method for making multispecific antibodies having heteromultimeric and common components
|
WO1998056906A1
(en)
|
1997-06-11 |
1998-12-17 |
Thoegersen Hans Christian |
Trimerising module
|
CN1203178C
(zh)
|
1997-10-27 |
2005-05-25 |
尤尼利弗公司 |
多价抗原结合蛋白
|
WO1999028471A2
(en)
|
1997-12-01 |
1999-06-10 |
The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
ANTIBODIES, INCLUDING Fv MOLECULES, AND IMMUNOCONJUGATES HAVING HIGH BINDING AFFINITY FOR MESOTHELIN AND METHODS FOR THEIR USE
|
DE69922159T2
(de)
|
1998-01-23 |
2005-12-01 |
Vlaams Interuniversitair Instituut Voor Biotechnologie |
Mehrzweck-antikörperderivate
|
HUP9900956A2
(hu)
|
1998-04-09 |
2002-04-29 |
Aventis Pharma Deutschland Gmbh. |
Egyláncú, több antigéntkötőhely kialakítására képes molekulák, előállításuk és alkalmazásuk
|
DE19819846B4
(de)
|
1998-05-05 |
2016-11-24 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Multivalente Antikörper-Konstrukte
|
GB9812545D0
(en)
|
1998-06-10 |
1998-08-05 |
Celltech Therapeutics Ltd |
Biological products
|
US6803448B1
(en)
|
1998-07-22 |
2004-10-12 |
Vanderbilt University |
GBS toxin receptor
|
ES2207278T3
(es)
|
1998-07-28 |
2004-05-16 |
Micromet Ag |
Heterominicuerpos.
|
US6333396B1
(en)
|
1998-10-20 |
2001-12-25 |
Enzon, Inc. |
Method for targeted delivery of nucleic acids
|
HUP0104693A3
(en)
|
1998-12-16 |
2003-12-29 |
Warner Lambert Co |
Treatment of arthritis with mek inhibitors
|
US6528481B1
(en)
|
1999-02-16 |
2003-03-04 |
The Burnam Institute |
NG2/HM proteoglycan-binding peptides that home to angiogenic vasculature and related methods
|
US7534866B2
(en)
|
2005-10-19 |
2009-05-19 |
Ibc Pharmaceuticals, Inc. |
Methods and compositions for generating bioactive assemblies of increased complexity and uses
|
US7527787B2
(en)
|
2005-10-19 |
2009-05-05 |
Ibc Pharmaceuticals, Inc. |
Multivalent immunoglobulin-based bioactive assemblies
|
PL207501B1
(pl)
|
1999-08-17 |
2010-12-31 |
Apotech R & D Sa |
Zastosowanie polipeptydu BCMA oraz przeciwciała skierowanego przeciwko BCMA
|
ATE388167T1
(de)
|
1999-09-30 |
2008-03-15 |
Kyowa Hakko Kogyo Kk |
Menschlicher antikörper gegen gangliosid gd3 für die transplantationskomplementarität bestimmente regionund derivate des antikörpers gegen das gangliosid gd3
|
ES2591102T3
(es)
|
1999-11-29 |
2016-11-24 |
The Trustees Of Columbia University In The City Of New York |
Aislamiento de cinco genes novedosos que codifican nuevos melanomas de tipo receptor de Fc implicados en la patogénesis del linfoma/melanoma
|
AU784634B2
(en)
|
1999-11-30 |
2006-05-18 |
Mayo Foundation For Medical Education And Research |
B7-H1, a novel immunoregulatory molecule
|
GB0000313D0
(en)
|
2000-01-10 |
2000-03-01 |
Astrazeneca Uk Ltd |
Formulation
|
US20040002068A1
(en)
|
2000-03-01 |
2004-01-01 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
JP2004509835A
(ja)
|
2000-03-06 |
2004-04-02 |
ユニヴァーシティ オブ ケンタッキー リサーチ ファンデーション |
血液癌前駆細胞を障害する方法およびその関連化合物
|
AU2001247616B2
(en)
|
2000-04-11 |
2007-06-14 |
Genentech, Inc. |
Multivalent antibodies and uses therefor
|
WO2001090192A2
(en)
|
2000-05-24 |
2001-11-29 |
Imclone Systems Incorporated |
Bispecific immunoglobulin-like antigen binding proteins and method of production
|
AU2001270609A1
(en)
|
2000-06-30 |
2002-01-14 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
Heterodimeric fusion proteins
|
EE05450B1
(et)
|
2000-07-19 |
2011-08-15 |
Warner-Lambert Company |
4-jodofenlaminobenshdroksaamhapete oksgeenitud estrid, nende kristallvormid ja farmatseutilised kompositsioonid ning kasutamine
|
CA2417185A1
(en)
|
2000-07-25 |
2002-01-31 |
Shui-On Leung |
Multivalent target binding protein
|
GB0020685D0
(en)
|
2000-08-22 |
2000-10-11 |
Novartis Ag |
Organic compounds
|
EP2351838A1
(en)
|
2000-10-20 |
2011-08-03 |
Chugai Seiyaku Kabushiki Kaisha |
Crosslinking agonistic antibodies
|
US7090843B1
(en)
|
2000-11-28 |
2006-08-15 |
Seattle Genetics, Inc. |
Recombinant anti-CD30 antibodies and uses thereof
|
AU2001291195A1
(en)
|
2000-12-01 |
2002-06-11 |
Parker Hughes Institute |
Nucleotide and protein sequence of helios 3 and methods of use
|
US6995162B2
(en)
|
2001-01-12 |
2006-02-07 |
Amgen Inc. |
Substituted alkylamine derivatives and methods of use
|
US7829084B2
(en)
|
2001-01-17 |
2010-11-09 |
Trubion Pharmaceuticals, Inc. |
Binding constructs and methods for use thereof
|
AU2002247826A1
(en)
|
2001-03-13 |
2002-09-24 |
University College London |
Specific binding members
|
CN1294148C
(zh)
|
2001-04-11 |
2007-01-10 |
中国科学院遗传与发育生物学研究所 |
环状单链三特异抗体
|
US6770622B2
(en)
|
2001-06-08 |
2004-08-03 |
Gary A. Jarvis |
N-terminally truncated galectin-3 for use in treating cancer
|
DK1399484T3
(da)
|
2001-06-28 |
2010-11-08 |
Domantis Ltd |
Dobbelt-specifik ligand og anvendelse af denne
|
US6833441B2
(en)
|
2001-08-01 |
2004-12-21 |
Abmaxis, Inc. |
Compositions and methods for generating chimeric heteromultimers
|
NZ531294A
(en)
|
2001-08-06 |
2005-11-25 |
Childrens Medical Center |
Synthesis and anti-tumor activity of nitrogen substituted thalidomide analogs
|
ES2466377T3
(es)
|
2001-08-23 |
2014-06-10 |
Rsr Limited |
Regiones epitópicas de un receptor de tirotropina (TSH), usos de las mismas y anticuerpos para las mismas
|
ES2276735T3
(es)
|
2001-09-14 |
2007-07-01 |
Affimed Therapeutics Ag |
Anticuerpos fv multimericos de cadena sencilla en tandem.
|
JP4716350B2
(ja)
|
2001-12-04 |
2011-07-06 |
ダナ−ファーバー キャンサー インスティテュート インク. |
潜伏期膜タンパク質に対する抗体およびそれらの使用
|
AU2002357072A1
(en)
|
2001-12-07 |
2003-06-23 |
Centocor, Inc. |
Pseudo-antibody constructs
|
IL162734A0
(en)
|
2002-02-01 |
2005-11-20 |
Ariad Gene Therapeutics Inc |
Phosphorus-containing compounds & uses thereof
|
US20040018557A1
(en)
|
2002-03-01 |
2004-01-29 |
Immunomedics, Inc. |
Bispecific antibody point mutations for enhancing rate of clearance
|
PL221491B1
(pl)
|
2002-03-08 |
2016-04-29 |
Eisai R&D Man Co |
Związki makrocykliczne, środek farmaceutyczny zawierający te związki oraz zastosowanie tych związków
|
PL401637A1
(pl)
|
2002-03-13 |
2013-05-27 |
Array Biopharma Inc. |
N3 alkilowane pochodne benzimidazolu jako inhibitory MEK
|
AU2003227504A1
(en)
|
2002-04-15 |
2003-10-27 |
Chugai Seiyaku Kabushiki Kaisha |
METHOD OF CONSTRUCTING scDb LIBRARY
|
TWI275390B
(en)
|
2002-04-30 |
2007-03-11 |
Wyeth Corp |
Process for the preparation of 7-substituted-3- quinolinecarbonitriles
|
US7446190B2
(en)
|
2002-05-28 |
2008-11-04 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acids encoding chimeric T cell receptors
|
SI2206517T1
(sl)
|
2002-07-03 |
2023-12-29 |
Ono Pharmaceutical Co., Ltd. |
Imunopotencirni sestavki,ki obsegajo protitelesa proti PD-L1
|
GB0215823D0
(en)
|
2002-07-09 |
2002-08-14 |
Astrazeneca Ab |
Quinazoline derivatives
|
ES2318167T3
(es)
|
2002-07-15 |
2009-05-01 |
The Trustees Of Princeton University |
Compuestos de union a iap.
|
US20050203142A1
(en)
|
2002-10-24 |
2005-09-15 |
Zeldis Jerome B. |
Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain
|
US20040087558A1
(en)
|
2002-10-24 |
2004-05-06 |
Zeldis Jerome B. |
Methods of using and compositions comprising selective cytokine inhibitory drugs for treatment, modification and management of pain
|
CN1787837A
(zh)
|
2002-11-15 |
2006-06-14 |
希龙公司 |
防止和治疗癌转移以及与癌转移相关的骨质损失的方法
|
EP1565492B1
(de)
|
2002-11-26 |
2006-12-20 |
B.R.A.H.M.S Aktiengesellschaft |
Nachweis von tsh-rezeptor-autoantikörpern mit affinitätsgereinigten antikörpern
|
JP4511943B2
(ja)
|
2002-12-23 |
2010-07-28 |
ワイス エルエルシー |
Pd−1に対する抗体およびその使用
|
EP1577288B1
(en)
|
2002-12-26 |
2014-07-23 |
Eisai R&D Management Co., Ltd. |
Selective estrogen receptor modulators
|
GB0230203D0
(en)
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Fc fusion
|
GB0305702D0
(en)
|
2003-03-12 |
2003-04-16 |
Univ Birmingham |
Bispecific antibodies
|
WO2004087758A2
(en)
|
2003-03-26 |
2004-10-14 |
Neopharm, Inc. |
Il 13 receptor alpha 2 antibody and methods of use
|
AU2004232928A1
(en)
|
2003-04-22 |
2004-11-04 |
Ibc Pharmaceuticals |
Polyvalent protein complex
|
EP1641826A2
(en)
|
2003-06-27 |
2006-04-05 |
Biogen Idec MA Inc. |
Use of hydrophobic-interaction-chromatography or hinge-region modifications for the production of homogeneous antibody-solutions
|
CA2530605A1
(en)
|
2003-06-27 |
2005-05-26 |
Diadexus, Inc. |
Pro104 antibody compositions and methods of use
|
WO2005004809A2
(en)
|
2003-07-01 |
2005-01-20 |
Immunomedics, Inc. |
Multivalent carriers of bi-specific antibodies
|
US7696322B2
(en)
|
2003-07-28 |
2010-04-13 |
Catalent Pharma Solutions, Inc. |
Fusion antibodies
|
CA2534659A1
(en)
|
2003-08-05 |
2005-02-17 |
Morphotek, Inc. |
A variant cell surface molecule associated with cancer
|
US7399865B2
(en)
|
2003-09-15 |
2008-07-15 |
Wyeth |
Protein tyrosine kinase enzyme inhibitors
|
JPWO2005035577A1
(ja)
|
2003-10-08 |
2007-11-22 |
協和醗酵工業株式会社 |
ガングリオシドgd3に特異的に結合する抗体組成物
|
AU2004279742A1
(en)
|
2003-10-08 |
2005-04-21 |
Kyowa Hakko Kirin Co., Ltd. |
Fused protein composition
|
US7612096B2
(en)
|
2003-10-23 |
2009-11-03 |
Celgene Corporation |
Methods for treatment, modification and management of radiculopathy using 1-oxo-2-(2,6-dioxopiperidin-3yl)-4-aminoisoindoline
|
US7435596B2
(en)
|
2004-11-04 |
2008-10-14 |
St. Jude Children's Research Hospital, Inc. |
Modified cell line and method for expansion of NK cell
|
CA2550996A1
(en)
|
2003-12-22 |
2005-07-14 |
Centocor, Inc. |
Methods for generating multimeric molecules
|
GB0329825D0
(en)
|
2003-12-23 |
2004-01-28 |
Celltech R&D Ltd |
Biological products
|
US20050266425A1
(en)
|
2003-12-31 |
2005-12-01 |
Vaccinex, Inc. |
Methods for producing and identifying multispecific antibodies
|
PT1704166E
(pt)
|
2004-01-07 |
2015-09-04 |
Novartis Vaccines & Diagnostic |
Anticorpo monoclonal específico de m-csf e respetivos usos
|
JP2007523061A
(ja)
|
2004-01-16 |
2007-08-16 |
ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン |
Smacペプチドミメティクスおよびその使用法
|
MXPA06008095A
(es)
|
2004-01-16 |
2007-03-28 |
Univ Michigan |
Mimeticos de smac conformacionalmente restringidos y sus usos.
|
US8383575B2
(en)
|
2004-01-30 |
2013-02-26 |
Paul Scherrer Institut |
(DI)barnase-barstar complexes
|
SI2511297T1
(sl)
|
2004-02-06 |
2015-07-31 |
Morphosys Ag |
Proti -CD38 humana protitelesa in njihova uporaba
|
EP1740173A4
(en)
|
2004-03-23 |
2009-05-27 |
Genentech Inc |
AZABICYCLOOCTAN IAP INHIBITORS
|
EP2253614B1
(en)
|
2004-04-07 |
2012-09-19 |
Novartis AG |
Inhibitors of IAP
|
US20070161696A1
(en)
|
2004-04-23 |
2007-07-12 |
Zeldis Jerome B |
Methods of using and compositions comprising selective cytokine inhibitory drugs for treatment, modification and management of pain
|
CN102973947A
(zh)
|
2004-06-01 |
2013-03-20 |
健泰科生物技术公司 |
抗体-药物偶联物和方法
|
ME01480B
(me)
|
2004-06-11 |
2014-04-20 |
Japan Tobacco Inc |
DERIVATI 5-AMIN0-2,4,7-TRIOKS0-3,4,7,8-TETRAHIDR0-2H-PIRID0[2,3-d]PIRIMIDINA I SRODNI SPOJEVI, NAMIJENJENI LIJEČENJU RAKA
|
ES2524449T3
(es)
|
2004-07-02 |
2014-12-09 |
Genentech, Inc. |
Inhibidores de IAP
|
WO2006010118A2
(en)
|
2004-07-09 |
2006-01-26 |
The Regents Of The University Of Michigan |
Conformationally constrained smac mimetics and the uses thereof
|
MX2007000490A
(es)
|
2004-07-12 |
2007-06-11 |
Idun Pharmaceuticals Inc |
Analogos de tetrapeptido.
|
EP1773766B1
(en)
|
2004-07-15 |
2014-04-02 |
Tetralogic Pharmaceuticals Corporation |
Iap binding compounds
|
WO2006020258A2
(en)
|
2004-07-17 |
2006-02-23 |
Imclone Systems Incorporated |
Novel tetravalent bispecific antibody
|
MX2007002856A
(es)
|
2004-09-02 |
2007-09-25 |
Genentech Inc |
Metodos para el uso de ligandos receptores de muerte y anticuerpos c20.
|
CN101080400A
(zh)
|
2004-09-03 |
2007-11-28 |
细胞基因公司 |
制备取代的2-(2,6-二氧代哌啶-3-基)-1-氧代异吲哚啉的方法
|
WO2006039238A2
(en)
|
2004-09-30 |
2006-04-13 |
The Goverment Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Irta2 antibodies and methods of use
|
JP4731867B2
(ja)
|
2004-10-01 |
2011-07-27 |
国立大学法人三重大学 |
Cd8陽性の細胞傷害性tリンパ球の誘導方法
|
ATE536177T1
(de)
|
2004-10-04 |
2011-12-15 |
Univ Minnesota |
Calixaren-basierte peptidkonformationsmimetika, verfahren zu ihrer verwendung und verfahren zu ihrer herstellung
|
ZA200704964B
(en)
|
2004-12-01 |
2008-10-29 |
Celgene Corp |
Methods and compositions using immunomodulatory compounds for the treatment of immunodeficiency disorders
|
JP2008524986A
(ja)
|
2004-12-10 |
2008-07-17 |
バイエル・ヘルスケア・アクチェンゲゼルシャフト |
タキサンに基づく薬物療法に対する悪性腫瘍の応答予測に有用な遺伝子変化
|
CN101146803A
(zh)
|
2004-12-20 |
2008-03-19 |
健泰科生物技术公司 |
Iap的吡咯烷抑制剂
|
MY146381A
(en)
|
2004-12-22 |
2012-08-15 |
Amgen Inc |
Compositions and methods relating relating to anti-igf-1 receptor antibodies
|
CA2594318A1
(en)
|
2005-01-12 |
2006-07-20 |
Medarex, Inc. |
Irta-2 antibodies and their uses
|
TR201901929T4
(tr)
|
2005-02-08 |
2019-03-21 |
Genzyme Corp |
TGFBeta'ya antikorlar.
|
CA2600505C
(en)
|
2005-03-10 |
2016-05-03 |
Morphotek, Inc. |
Anti-mesothelin antibodies
|
PT1866339E
(pt)
|
2005-03-25 |
2013-09-03 |
Gitr Inc |
Moléculas de ligação a gitr e suas utilizações
|
CN101198698B
(zh)
|
2005-03-31 |
2014-03-19 |
中外制药株式会社 |
通过调节多肽缔合制备多肽的方法
|
AU2006232920B2
(en)
|
2005-04-06 |
2011-09-29 |
Ibc Pharmaceuticals, Inc. |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses
|
JP5838021B2
(ja)
|
2005-04-15 |
2015-12-24 |
マクロジェニクス,インコーポレーテッド |
共有結合型ダイアボディとその使用
|
KR101339628B1
(ko)
|
2005-05-09 |
2013-12-09 |
메다렉스, 인코포레이티드 |
예정 사멸 인자 1(pd-1)에 대한 인간 모노클로날 항체, 및 항-pd-1 항체를 단독 사용하거나 기타 면역 요법제와 병용한 암 치료 방법
|
US20060263367A1
(en)
|
2005-05-23 |
2006-11-23 |
Fey Georg H |
Bispecific antibody devoid of Fc region and method of treatment using same
|
EP1726650A1
(en)
|
2005-05-27 |
2006-11-29 |
Universitätsklinikum Freiburg |
Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen
|
AU2006259536A1
(en)
|
2005-06-15 |
2006-12-28 |
Schering Corporation |
Anti-IGF1R antibody formulations
|
NZ564592A
(en)
|
2005-07-01 |
2011-11-25 |
Medarex Inc |
Human monoclonal antibodies to programmed death ligand 1 (PD-L1)
|
JP4557003B2
(ja)
|
2005-07-01 |
2010-10-06 |
株式会社村田製作所 |
多層セラミック基板およびその製造方法ならびに多層セラミック基板作製用複合グリーンシート
|
WO2007004606A1
(ja)
|
2005-07-04 |
2007-01-11 |
Nikon Vision Co., Ltd. |
測距装置
|
CA2618218C
(en)
|
2005-07-21 |
2015-06-30 |
Ardea Biosciences, Inc. |
N-(arylamino)-sulfonamide inhibitors of mek
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
SG2014010029A
(en)
|
2005-08-19 |
2014-08-28 |
Abbott Lab |
Dual variable domain immunoglobin and uses thereof
|
EP1757622B1
(en)
|
2005-08-26 |
2009-12-23 |
PLS Design GmbH |
Bivalent IgY antibody constructs for diagnostic and therapeutic applications
|
AU2006285144A1
(en)
|
2005-08-31 |
2007-03-08 |
Celgene Corporation |
Isoindole-imide compounds and compositions comprising and methods of using the same
|
WO2007044887A2
(en)
|
2005-10-11 |
2007-04-19 |
Transtarget, Inc. |
Method for producing a population of homogenous tetravalent bispecific antibodies
|
JP5102772B2
(ja)
|
2005-11-29 |
2012-12-19 |
ザ・ユニバーシティ・オブ・シドニー |
デミボディ:二量体化活性化治療剤
|
US20070128636A1
(en)
|
2005-12-05 |
2007-06-07 |
Baker Joffre B |
Predictors Of Patient Response To Treatment With EGFR Inhibitors
|
NZ568551A
(en)
|
2005-12-08 |
2012-03-30 |
Medarex Inc |
Human monoclonal antibodies to Fucosyl-GM1 and methods using anti-Fucosyl-GM1
|
ZA200804717B
(en)
|
2005-12-29 |
2010-02-24 |
Anthrogenesis Corp |
Improved composition for collecting and preserving a placental stem cells and methods of using the composition
|
EP1806365A1
(en)
|
2006-01-05 |
2007-07-11 |
Boehringer Ingelheim International GmbH |
Antibody molecules specific for fibroblast activation protein and immunoconjugates containing them
|
NZ596494A
(en)
|
2006-01-13 |
2013-07-26 |
Us Gov Nat Inst Health |
Codon optimized il-15 and il-15r-alpha genes for expression in mammalian cells
|
AU2007215013A1
(en)
|
2006-02-15 |
2007-08-23 |
Imclone Systems Incorporated |
Functional antibodies
|
NZ591252A
(en)
|
2006-03-17 |
2012-06-29 |
Biogen Idec Inc |
Methods of designing antibody or antigen binding fragments thereof with substituted non-covarying amino acids
|
ATE509033T1
(de)
|
2006-03-20 |
2011-05-15 |
Univ California |
Manipulierte anti-prostatastammzellenantigen (psca)-antikörper für krebs-targeting
|
PT1999154E
(pt)
|
2006-03-24 |
2013-01-24 |
Merck Patent Gmbh |
Domínios proteicos heterodiméricos modificados
|
US8946391B2
(en)
|
2006-03-24 |
2015-02-03 |
The Regents Of The University Of California |
Construction of a multivalent scFv through alkyne-azide 1,3-dipolar cycloaddition
|
US8603466B2
(en)
|
2006-03-29 |
2013-12-10 |
King's College London |
Agonist antibodies against TSHR
|
EP3345616A1
(en)
|
2006-03-31 |
2018-07-11 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody modification method for purifying bispecific antibody
|
HUE035654T2
(en)
|
2006-04-19 |
2018-05-28 |
Novartis Ag |
6-o-substituted benzoxazole and benzothiazole compounds and methods for inhibiting CSF-1R signaling
|
TWI395754B
(zh)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
人類化之c-kit抗體
|
ES2382777T3
(es)
|
2006-05-03 |
2012-06-13 |
Government Of The United States Of America,As Represented By The Secretary, Department Of Health And Human Services |
Receptor de células T quimérico y materiales relacionados y métodos de uso
|
WO2008011216A2
(en)
|
2006-05-16 |
2008-01-24 |
Pro-Pharmaceuticals, Inc. |
Galactose-pronged polysaccharides in a formulation for antifibrotic therapies
|
US20070269827A1
(en)
|
2006-05-18 |
2007-11-22 |
Oklahoma Medical Research Foundation |
Predicting and Diagnosing Patients With Autoimmune Disease
|
ES2469676T3
(es)
|
2006-05-25 |
2014-06-18 |
Bayer Intellectual Property Gmbh |
Complejos moleculares dim�ricos
|
US20070274985A1
(en)
|
2006-05-26 |
2007-11-29 |
Stefan Dubel |
Antibody
|
WO2007146968A2
(en)
|
2006-06-12 |
2007-12-21 |
Trubion Pharmaceuticals, Inc. |
Single-chain multivalent binding proteins with effector function
|
KR101342035B1
(ko)
|
2006-06-20 |
2013-12-16 |
한국과학기술연구원 |
신장독성 및 부작용 유발 약물 검색용 바이오마커 및 이를이용한 신장독성 및 부작용 유발 약물 검색 방법
|
AU2007285763B2
(en)
|
2006-08-18 |
2011-12-15 |
Armagen Technologies, Inc. |
Agents for blood-brain barrier delivery
|
BRPI0714635A2
(pt)
|
2006-08-21 |
2013-06-18 |
Genentech Inc |
compostos, composiÇço farmacÊutica, mÉtodo para inibir, o crescimento celular anormal ou tratar uma disfunÇço hiperproliferativa, mÉtodo para tratar uma doenÇa inflamatària e mÉtodo para tratar uma doenÇa autoimune
|
US8877780B2
(en)
|
2006-08-30 |
2014-11-04 |
Celgene Corporation |
5-substituted isoindoline compounds
|
EP2471816A1
(en)
|
2006-08-30 |
2012-07-04 |
Genentech, Inc. |
Multispecific antibodies
|
AU2007304590A1
(en)
|
2006-10-04 |
2008-04-10 |
Cancer Research Technology Limited |
Generation of a cancer-specific immune response toward MUC1 and cancer specific MUC1 antibodies
|
FR2906808B1
(fr)
|
2006-10-10 |
2012-10-05 |
Univ Nantes |
Utilisation d'anticorps monoclonaux specifiques de la forme o-acetylee du ganglioside gd2 dans le traitement de certains cancers
|
SG176476A1
(en)
|
2006-11-02 |
2011-12-29 |
Daniel J Capon |
Hybrid immunoglobulins with moving parts
|
MY188335A
(en)
|
2006-11-22 |
2021-11-30 |
Incyte Holdings Corp |
Imidazotriazines and imidazopyrimidines as kinase inhibitors
|
AU2007324472A1
(en)
|
2006-11-23 |
2008-05-29 |
Novartis Ag |
5-sulfanylmethyl-pyrazolo [1,5-a] pyrimidin-7-ol derivatives as CXCR2 antagonists
|
CN101541767A
(zh)
|
2006-11-23 |
2009-09-23 |
诺瓦提斯公司 |
嘧啶类物质及其作为cxcr2受体拮抗剂的应用
|
ATE484505T1
(de)
|
2006-11-23 |
2010-10-15 |
Novartis Ag |
5-sulfanylmethylä1,2,4ütriazolä1,5-aüpyrimidin- - olderivate als cxcr2-antagonisten
|
WO2008101234A2
(en)
|
2007-02-16 |
2008-08-21 |
Sloan-Kettering Institute For Cancer Research |
Anti ganglioside gd3 antibodies and uses thereof
|
WO2008103645A2
(en)
|
2007-02-19 |
2008-08-28 |
Wisconsin Alumni Research Foundation |
Prostate cancer and melanoma antigens
|
US20100158927A1
(en)
|
2007-03-29 |
2010-06-24 |
Technion Research & Development Foundation Ltd. |
Antibodies, methods and kits for diagnosing and treating melanoma
|
NZ614857A
(en)
|
2007-03-29 |
2015-04-24 |
Genmab As |
Bispecific antibodies and methods for production thereof
|
WO2008127735A1
(en)
|
2007-04-13 |
2008-10-23 |
Stemline Therapeutics, Inc. |
Il3ralpha antibody conjugates and uses thereof
|
US20080260738A1
(en)
|
2007-04-18 |
2008-10-23 |
Moore Margaret D |
Single chain fc, methods of making and methods of treatment
|
EP1987839A1
(en)
|
2007-04-30 |
2008-11-05 |
I.N.S.E.R.M. Institut National de la Sante et de la Recherche Medicale |
Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
|
NZ598890A
(en)
|
2007-04-30 |
2013-10-25 |
Genentech Inc |
Inhibitors of iap
|
US9244059B2
(en)
|
2007-04-30 |
2016-01-26 |
Immutep Parc Club Orsay |
Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
|
EP2160401B1
(en)
|
2007-05-11 |
2014-09-24 |
Altor BioScience Corporation |
Fusion molecules and il-15 variants
|
JP2010190572A
(ja)
|
2007-06-01 |
2010-09-02 |
Sapporo Medical Univ |
IL13Ra2に対する抗体およびこれを含む診断・治療薬
|
CA2691357C
(en)
|
2007-06-18 |
2014-09-23 |
N.V. Organon |
Antibodies to human programmed death receptor pd-1
|
CA2694990A1
(en)
|
2007-07-31 |
2009-02-05 |
Merck Sharp & Dohme Corp. |
Igf-1r specific antibodies useful in the detection and diagnosis of cellular proliferative disorders
|
US20090155275A1
(en)
|
2007-07-31 |
2009-06-18 |
Medimmune, Llc |
Multispecific epitope binding proteins and uses thereof
|
EP2178914A2
(en)
|
2007-08-15 |
2010-04-28 |
Bayer Schering Pharma Aktiengesellschaft |
Monospecific and multispecific antibodies and method of use
|
KR101584823B1
(ko)
|
2007-09-12 |
2016-01-22 |
제넨테크, 인크. |
포스포이노시타이드 3-키나제 저해제 화합물과 화학치료제의 배합물 및 이의 사용방법
|
JP5535074B2
(ja)
|
2007-10-01 |
2014-07-02 |
ブリストル−マイヤーズ スクウィブ カンパニー |
メソテリンに結合するヒト抗体およびその使用
|
EP2044949A1
(en)
|
2007-10-05 |
2009-04-08 |
Immutep |
Use of recombinant lag-3 or the derivatives thereof for eliciting monocyte immune response
|
JP2009092508A
(ja)
|
2007-10-09 |
2009-04-30 |
Norihiro Nishimoto |
リウマチ治療剤の効果の予測方法
|
US8354528B2
(en)
|
2007-10-25 |
2013-01-15 |
Genentech, Inc. |
Process for making thienopyrimidine compounds
|
BRPI0819909B8
(pt)
|
2007-11-26 |
2021-05-25 |
Bayer Ip Gmbh |
anticorpo sintético humano ou humanizado isolado ou um fragmento funcional do mesmo, fragmento funcional e composição farmacêutica
|
MX2010005783A
(es)
|
2007-11-27 |
2010-08-10 |
Ablynx Nv |
Secuencias de aminoacidos dirigidas contra citoquinas heterodimericas y/o sus receptores y polipeptidos que comprenden las mismas.
|
BRPI0819693A2
(pt)
|
2007-11-30 |
2020-08-18 |
Glaxo Group Limited |
Construção de ligação de antígeno, método para tratar um paciente que sofre de câncer ou uma doença inflamatória, sequência de polinucleotídeo, polinucleotídeo, célula hospedeira transformada ou transfectada recombinante, método para produziruma construção de ligação de antígeno, e, composição farmacêutica
|
US20100247580A1
(en)
|
2007-11-30 |
2010-09-30 |
Thierry Coche |
Method for Classifying Cancer Patients as Responder or Non-Responder to Immunotherapy
|
CN101945870B
(zh)
|
2007-12-19 |
2012-10-03 |
健泰科生物技术公司 |
5-苯氨基咪唑并吡啶和使用方法
|
US8227577B2
(en)
|
2007-12-21 |
2012-07-24 |
Hoffman-La Roche Inc. |
Bivalent, bispecific antibodies
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
US8242247B2
(en)
|
2007-12-21 |
2012-08-14 |
Hoffmann-La Roche Inc. |
Bivalent, bispecific antibodies
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
KR100957051B1
(ko)
|
2007-12-28 |
2010-05-13 |
한국과학기술연구원 |
니트로푸란토인 처리에 따른, 폐독성 유발 약물 검색용마커유전자 및 이를 이용한 검색 방법
|
US8592562B2
(en)
|
2008-01-07 |
2013-11-26 |
Amgen Inc. |
Method for making antibody Fc-heterodimeric molecules using electrostatic steering effects
|
GB2456390A
(en)
|
2008-01-15 |
2009-07-22 |
Glaxo Group Ltd |
Bipolar disorder treatments
|
WO2009094592A2
(en)
|
2008-01-23 |
2009-07-30 |
Perlegen Sciences, Inc. |
Genetic basis of alzheimer's disease and diagnosis and treatment thereof
|
WO2009101611A1
(en)
|
2008-02-11 |
2009-08-20 |
Curetech Ltd. |
Monoclonal antibodies for tumor treatment
|
MX2010009416A
(es)
|
2008-02-26 |
2010-09-24 |
Novartis Ag |
Compuestos heterociclicos como inhibidores de cxcr2.
|
WO2009114335A2
(en)
|
2008-03-12 |
2009-09-17 |
Merck & Co., Inc. |
Pd-1 binding proteins
|
US20090299645A1
(en)
|
2008-03-19 |
2009-12-03 |
Brandon Colby |
Genetic analysis
|
US20110229498A1
(en)
|
2008-05-08 |
2011-09-22 |
The Johns Hopkins University |
Compositions and methods for modulating an immune response
|
AR071891A1
(es)
|
2008-05-30 |
2010-07-21 |
Imclone Llc |
Anticuerpos humanos anti-flt3 (receptor tirosina cinasa 3 tipo fms humano)
|
US8168784B2
(en)
|
2008-06-20 |
2012-05-01 |
Abbott Laboratories |
Processes to make apoptosis promoters
|
GB0906579D0
(en)
|
2009-04-16 |
2009-05-20 |
Vernalis R&D Ltd |
Pharmaceuticals, compositions and methods of making and using the same
|
UA103198C2
(en)
|
2008-08-04 |
2013-09-25 |
Новартис Аг |
Squaramide derivatives as cxcr2 antagonists
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
NZ591176A
(en)
|
2008-08-22 |
2012-11-30 |
Novartis Ag |
Pyrrolopyrimidine compounds as cdk inhibitors
|
EP2328920A2
(en)
|
2008-08-25 |
2011-06-08 |
Amplimmune, Inc. |
Targeted costimulatory polypeptides and methods of use to treat cancer
|
NZ591130A
(en)
|
2008-08-25 |
2012-09-28 |
Amplimmune Inc |
Compositions comprising a PD-1 antagonists and cyclophosphamide and methods of use thereof
|
JP2012501670A
(ja)
|
2008-09-12 |
2012-01-26 |
アイシス・イノベーション・リミテッド |
Pd−1特異抗体およびその使用
|
JP2012503203A
(ja)
|
2008-09-19 |
2012-02-02 |
ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション |
基底乳癌腫の診断および処置のためのcspg4に対するモノクローナル抗体
|
MX2011003195A
(es)
|
2008-09-26 |
2011-08-12 |
Dana Farber Cancer Inst Inc |
Anticuerpos anti-pd-1, pd-l1 y pd-l2 humanos y usos de los mismos.
|
EP2177615A1
(en)
|
2008-10-10 |
2010-04-21 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Method for a genome wide identification of expression regulatory sequences and use of genes and molecules derived thereof for the diagnosis and therapy of metabolic and/or tumorous diseases
|
KR20180000750A
(ko)
|
2008-10-29 |
2018-01-03 |
셀진 코포레이션 |
암의 치료에 사용하기 위한 이소인돌린 화합물
|
WO2010063802A1
(en)
|
2008-12-05 |
2010-06-10 |
Novartis Ag |
3, 4-di-substituted cyclobutene- 1, 2 -diones as cxcr2 receptor antagonists
|
CN104479018B
(zh)
|
2008-12-09 |
2018-09-21 |
霍夫曼-拉罗奇有限公司 |
抗-pd-l1抗体及它们用于增强t细胞功能的用途
|
EP2210891A1
(en)
|
2009-01-26 |
2010-07-28 |
Domain Therapeutics |
New adenosine receptor ligands and uses thereof
|
EP3192811A1
(en)
|
2009-02-09 |
2017-07-19 |
Université d'Aix-Marseille |
Pd-1 antibodies and pd-l1 antibodies and uses thereof
|
EP2408775B1
(en)
|
2009-03-20 |
2015-06-17 |
SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. |
Oxidated derivatives of triazolylpurines useful as ligands of the adenosine a2a receptor and their use as medicaments
|
RU2583270C2
(ru)
|
2009-04-01 |
2016-05-10 |
Дженентек, Инк. |
АНТИТЕЛА К FcRH5, ИХ ИММУНОКОНЪЮГАТЫ И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
|
EP2414399A1
(en)
|
2009-04-01 |
2012-02-08 |
F. Hoffmann-La Roche AG |
Anti-fcrh5 antibodies and immunoconjugates and methods of use
|
CN104558179A
(zh)
|
2009-04-27 |
2015-04-29 |
协和发酵麒麟株式会社 |
用于治疗血液肿瘤的抗IL-3Rα抗体
|
ES2708124T3
(es)
|
2009-04-27 |
2019-04-08 |
Oncomed Pharm Inc |
Procedimiento para preparar moléculas heteromultiméricas
|
JP2013501008A
(ja)
|
2009-08-05 |
2013-01-10 |
バーシテック リミテッド |
抗ウイルス性化合物ならびにそれを含む医薬組成物
|
US9212177B2
(en)
|
2009-08-05 |
2015-12-15 |
Versitech Limited |
Antiviral compounds and methods of making and using thereof
|
TWI445708B
(zh)
|
2009-09-02 |
2014-07-21 |
Irm Llc |
作為tlr活性調節劑之化合物及組合物
|
IN2015DN02826A
(es)
|
2009-09-03 |
2015-09-11 |
Merck Sharp & Dohme |
|
WO2011056505A1
(en)
|
2009-10-26 |
2011-05-12 |
Abbott Laboratories |
Detection of chromosomal abnormalities associated with prognosis of non small cell lung cancer
|
EP2504028A4
(en)
|
2009-11-24 |
2014-04-09 |
Amplimmune Inc |
SIMULTANEOUS INHIBITION OF PD-L1 / PD-L2
|
KR101573109B1
(ko)
|
2009-11-24 |
2015-12-01 |
메디뮨 리미티드 |
B7―h1에 대한 표적화된 결합 물질
|
RU2673908C2
(ru)
|
2009-12-02 |
2018-12-03 |
Имэджинэб, Инк. |
Мини-антитела j591 и цис-диатела для направленной доставки простата-специфичного мембранного антигена (psma) человека и способы их применения
|
US8440693B2
(en)
|
2009-12-22 |
2013-05-14 |
Novartis Ag |
Substituted isoquinolinones and quinazolinones
|
CN102770453B
(zh)
|
2009-12-23 |
2014-10-08 |
合成免疫股份有限公司 |
抗flt3抗体及其使用方法
|
RU2625791C2
(ru)
|
2010-02-05 |
2017-07-19 |
Хептейрес Терапьютикс Лимитед |
Производные 1,2,4-триазин-4-амина
|
DK3202460T3
(da)
|
2010-02-11 |
2019-07-29 |
Celgene Corp |
Arylmethoxy-isoindolinderivater og sammensætninger omfattende og fremgangsmåder til anvendelser af samme
|
SG10201501342UA
(en)
|
2010-02-24 |
2015-04-29 |
Immunogen Inc |
Folate receptor 1 antibodies and immunoconjugates and uses thereof
|
WO2011110604A1
(en)
|
2010-03-11 |
2011-09-15 |
Ucb Pharma, S.A. |
Pd-1 antibody
|
ES2365960B1
(es)
|
2010-03-31 |
2012-06-04 |
Palobiofarma, S.L |
Nuevos antagonistas de los receptores de adenosina.
|
SG10201800757TA
(en)
|
2010-04-20 |
2018-02-27 |
Genmab As |
Heterodimeric antibody fc-containing proteins and methods for production thereof
|
US20130237454A1
(en)
|
2010-05-12 |
2013-09-12 |
Steven E. Schutzer |
Diagnostic markers for neuropsychiatric disease
|
US20120142701A1
(en)
|
2010-05-28 |
2012-06-07 |
The University Of Hong Kong |
Compounds and methods for the treatment of proliferative diseases
|
WO2011151941A1
(ja)
|
2010-06-04 |
2011-12-08 |
国立大学法人東京大学 |
制御性t細胞の増殖または集積を誘導する作用を有する組成物
|
WO2011156518A2
(en)
|
2010-06-10 |
2011-12-15 |
Aragon Pharmaceuticals, Inc. |
Estrogen receptor modulators and uses thereof
|
HUE040213T2
(hu)
|
2010-06-11 |
2019-02-28 |
Kyowa Hakko Kirin Co Ltd |
Anti-TIM antitest
|
US9242014B2
(en)
|
2010-06-15 |
2016-01-26 |
The Regents Of The University Of California |
Receptor tyrosine kinase-like orphan receptor 1 (ROR1) single chain Fv antibody fragment conjugates and methods of use thereof
|
US8853423B2
(en)
|
2010-06-17 |
2014-10-07 |
Seragon Pharmaceuticals, Inc. |
Indane estrogen receptor modulators and uses thereof
|
CA2802344C
(en)
|
2010-06-18 |
2023-06-13 |
The Brigham And Women's Hospital, Inc. |
Bi-specific antibodies against tim-3 and pd-1 for immunotherapy in chronic immune conditions
|
JP6029581B2
(ja)
|
2010-06-19 |
2016-11-24 |
メモリアル スローン−ケタリング キャンサー センター |
抗gd2抗体
|
US8907053B2
(en)
|
2010-06-25 |
2014-12-09 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
US20130281304A1
(en)
|
2010-08-13 |
2013-10-24 |
Andrew P. Feinberg |
Comprehensive Methylome Map of Myeloid and Lymphoid Commitment from Hematopoietic Proenitors
|
EP2614143B1
(en)
|
2010-09-08 |
2018-11-07 |
Baylor College Of Medicine |
Immunotherapy of non-small lung cancer using genetically engineered gd2-specific t cells
|
GB2483736B
(en)
|
2010-09-16 |
2012-08-29 |
Aragon Pharmaceuticals Inc |
Estrogen receptor modulators and uses thereof
|
AU2011317211B2
(en)
|
2010-10-22 |
2015-04-16 |
Dana-Farber Cancer Institute, Inc. |
Discovery of regulatory T cells programmed to suppress an immune response
|
AU2011328246B2
(en)
|
2010-11-08 |
2016-06-30 |
Ablynx N.V. |
CXCR2 binding polypeptides
|
CN108103085A
(zh)
|
2010-12-09 |
2018-06-01 |
宾夕法尼亚大学董事会 |
嵌合抗原受体-修饰的t细胞治疗癌症的用途
|
JOP20210044A1
(ar)
|
2010-12-30 |
2017-06-16 |
Takeda Pharmaceuticals Co |
الأجسام المضادة لـ cd38
|
WO2012135854A2
(en)
|
2011-04-01 |
2012-10-04 |
Memorial Sloan-Kettering Cancer Center |
Antibodies to cytosolic peptides
|
RU2625034C2
(ru)
|
2011-04-20 |
2017-07-11 |
МЕДИММЬЮН, ЭлЭлСи |
Антитела и другие молекулы, которые связывают в7-н1 и pd-1
|
AR086044A1
(es)
|
2011-05-12 |
2013-11-13 |
Imclone Llc |
Anticuerpos que se unen especificamente a un dominio extracelular de c-kit y usos de los mismos
|
CN106279418A
(zh)
|
2011-05-27 |
2017-01-04 |
葛兰素集团有限公司 |
Bcma(cd269/tnfrsf17)结合蛋白
|
BR112013030958B1
(pt)
|
2011-06-03 |
2022-02-08 |
Xoma Technology Ltd |
Anticorpo que se liga ao fator de transformação de crescimento beta, composição farmacêutica, usos dos mesmos, molécula de ácido nucleico, vetor de expressão, e método para produção de um anticorpo
|
CA2838275C
(en)
|
2011-06-06 |
2021-08-10 |
University Of Iowa Research Foundation |
Methods for inhibiting muscle atrophy
|
EP2723362A1
(en)
|
2011-06-21 |
2014-04-30 |
Innate Pharma |
NKp46-MEDIATED NK CELL TUNING
|
EP2537933A1
(en)
|
2011-06-24 |
2012-12-26 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
An IL-15 and IL-15Ralpha sushi domain based immunocytokines
|
WO2013006490A2
(en)
|
2011-07-01 |
2013-01-10 |
Cellerant Therapeutics, Inc. |
Antibodies that specifically bind to tim3
|
CN103782173B
(zh)
|
2011-07-01 |
2018-07-13 |
贝克曼考尔特公司 |
调节t细胞和识别、获得、以及用于治疗基于免疫的紊乱的方法
|
UA117220C2
(uk)
|
2011-08-01 |
2018-07-10 |
Дженентек, Інк. |
Способи лікування раку з використанням антагоністів, що зв'язуються з віссю pd-1, і інгібіторів mek
|
KR102024955B1
(ko)
|
2011-09-02 |
2019-09-24 |
노파르티스 아게 |
치환된 시클로부텐디온 항염 화합물의 콜린 염
|
WO2013037118A1
(zh)
|
2011-09-16 |
2013-03-21 |
上海长海医院 |
***癌的生物学标志物、治疗靶点及其用途
|
WO2013040557A2
(en)
|
2011-09-16 |
2013-03-21 |
The Trustees Of The University Of Pennsylvania |
Rna engineered t cells for the treatment of cancer
|
ES2795023T3
(es)
|
2011-09-16 |
2020-11-20 |
Baylor College Medicine |
Reconocimiento específico del microambiente tumoral mediante el uso de células NKT manipuladas
|
ITMO20110270A1
(it)
|
2011-10-25 |
2013-04-26 |
Sara Caldrer |
Una cellula effettrice modificata per il trattamento di neoplasie esprimenti il disialonganglioside gd2
|
EP3674320A3
(en)
|
2011-10-27 |
2020-08-12 |
Genmab A/S |
Production of heterodimeric proteins
|
WO2013063419A2
(en)
|
2011-10-28 |
2013-05-02 |
The Trustees Of The University Of Pennsylvania |
A fully human, anti-mesothelin specific chimeric immune receptor for redirected mesothelin-expressing cell targeting
|
US10391126B2
(en)
|
2011-11-18 |
2019-08-27 |
Board Of Regents, The University Of Texas System |
CAR+ T cells genetically modified to eliminate expression of T-cell receptor and/or HLA
|
HUE051954T2
(hu)
|
2011-11-28 |
2021-03-29 |
Merck Patent Gmbh |
ANTI-PD-L1 ellenanyagok és alkalmazásaik
|
CN116942833A
(zh)
|
2011-12-01 |
2023-10-27 |
国立大学法人 东京大学 |
诱导调节性t细胞的增殖或积累的人源细菌
|
US9439768B2
(en)
|
2011-12-08 |
2016-09-13 |
Imds Llc |
Glenoid vault fixation
|
US9481866B2
(en)
|
2011-12-16 |
2016-11-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of producing T cell populations enriched for stable regulatory T-cells
|
IN2014CN04935A
(es)
|
2011-12-31 |
2015-09-18 |
Moni Abraham Kuriakose |
|
JO3357B1
(ar)
|
2012-01-26 |
2019-03-13 |
Novartis Ag |
مركبات إيميدازوبيروليدينون
|
EP2814846B1
(en)
|
2012-02-13 |
2020-01-08 |
Seattle Children's Hospital d/b/a Seattle Children's Research Institute |
Bispecific chimeric antigen receptors and therapeutic uses thereof
|
JP2015513399A
(ja)
|
2012-02-22 |
2015-05-14 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
癌の治療のために有用なt細胞の存続的集団を作製するための組成物および方法
|
CN104245923B
(zh)
|
2012-03-02 |
2018-04-20 |
加州大学评议会 |
同种异型抗原‑反应性调节t细胞的增殖
|
CA3209571A1
(en)
|
2012-03-23 |
2013-09-26 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-mesothelin chimeric antigen receptors
|
GB201207297D0
(en)
|
2012-04-26 |
2012-06-06 |
Senzagen Ab |
Analytical methods and arrays for use in the same
|
KR20150006000A
(ko)
|
2012-05-01 |
2015-01-15 |
제넨테크, 인크. |
항-pmel17 항체 및 면역접합체
|
US9328174B2
(en)
|
2012-05-09 |
2016-05-03 |
Novartis Ag |
Chemokine receptor binding polypeptides
|
PT2850106T
(pt)
|
2012-05-18 |
2022-07-18 |
Aptevo Res & Development Llc |
Imunofusão biespecífica (bif) de scfv de ligação a cd123 e cd3
|
WO2013179174A1
(en)
|
2012-05-29 |
2013-12-05 |
Koninklijke Philips N.V. |
Lighting arrangement
|
EP2854843A4
(en)
|
2012-05-31 |
2016-06-01 |
Sorrento Therapeutics Inc |
ANTIGEN BINDING PROTEINS THAT BIND PD-L1
|
GB201213571D0
(en)
|
2012-07-31 |
2012-09-12 |
Univ Leuven Kath |
Growth factor cocktail to enhnce osteogenic differentiayion of mesenchymal
|
WO2013192294A1
(en)
|
2012-06-20 |
2013-12-27 |
Boston 3T Biotechnologies, Inc. |
Cellular therapies for treating and preventing cancers and other immune system disorders
|
EP2682750A1
(en)
|
2012-07-02 |
2014-01-08 |
Sotio a.s. |
In vitro method for the diagnosis and surveillance of cancer
|
UY34887A
(es)
|
2012-07-02 |
2013-12-31 |
Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware |
Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos
|
US9845356B2
(en)
|
2012-08-03 |
2017-12-19 |
Dana-Farber Cancer Institute, Inc. |
Single agent anti-PD-L1 and PD-L2 dual binding antibodies and methods of use
|
PL2884999T3
(pl)
|
2012-08-20 |
2021-07-05 |
Fred Hutchinson Cancer Research Center |
Sposób i kompozycje do immunoterapii komórkowej
|
EA201590535A1
(ru)
|
2012-09-10 |
2015-07-30 |
Селджин Корпорейшн |
Способы лечения локально прогрессирующего запущенного рака молочной железы
|
EP2900061B1
(en)
|
2012-09-17 |
2020-01-22 |
Galectin Therapeutics Inc. |
Method for enhancing specific immunotherapies in cancer treatment
|
CN107892719B
(zh)
|
2012-10-04 |
2022-01-14 |
达纳-法伯癌症研究所公司 |
人单克隆抗-pd-l1抗体和使用方法
|
CA2886120A1
(en)
|
2012-10-08 |
2014-04-17 |
St. Jude Children's Research Hospital |
Therapies based on control of regulatory t cell stability and function via a neuropilin-1:semaphorin axis
|
AU2013334610B2
(en)
|
2012-10-24 |
2018-09-13 |
Novartis Ag |
IL-15R alpha forms, cells expressing IL-15R alpha forms, and therapeutic uses of IL-15R alpha and IL-15/IL-15R alpha complexes
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Bcma抗原結合蛋白質
|
AR093984A1
(es)
|
2012-12-21 |
2015-07-01 |
Merck Sharp & Dohme |
Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano
|
CN111848796A
(zh)
|
2013-02-05 |
2020-10-30 |
英格玛布有限责任公司 |
用于选择针对bcma的抗体的方法
|
WO2014122467A1
(en)
|
2013-02-06 |
2014-08-14 |
Loxbridge Research Llp |
Systems and methods for early disease detection and real-time disease monitoring
|
MA38325B1
(fr)
|
2013-02-19 |
2019-03-29 |
Novartis Ag |
Dérivés de benzothiophène et compositions correspondantes en tant qu'agents de dégradation sélectifs des récepteurs des œstrogènes
|
CA2901960C
(en)
|
2013-02-20 |
2022-10-04 |
Novartis Ag |
Treatment of cancer using humanized anti-egfrviii chimeric antigen receptor
|
ES2814962T3
(es)
|
2013-02-20 |
2021-03-29 |
Novartis Ag |
Fijación eficaz como objetivo de la leucemia humana primaria utilizando células T modificadas con receptor de antígeno quimérico anti-CD123
|
WO2014138805A1
(en)
|
2013-03-14 |
2014-09-18 |
Csl Limited |
Anti il-3r alpha agents and uses thereof
|
WO2014153069A2
(en)
|
2013-03-14 |
2014-09-25 |
Children's Medical Center Corporation |
Compositions and methods for reprogramming hematopoietic stem cell lineages
|
WO2014138819A1
(en)
|
2013-03-14 |
2014-09-18 |
Csl Limited |
Agents that neutralize il-3 signaling and uses thereof
|
ME03796B
(me)
|
2013-03-15 |
2021-04-20 |
Glaxosmithkline Ip Dev Ltd |
Anti-lag-3 vezujući proteini
|
EP2971164B1
(en)
|
2013-03-15 |
2023-07-26 |
Veracyte, Inc. |
Methods and compositions for classification of samples
|
AR095374A1
(es)
|
2013-03-15 |
2015-10-14 |
Amgen Res (Munich) Gmbh |
Moléculas de unión para bcma y cd3
|
US9657105B2
(en)
|
2013-03-15 |
2017-05-23 |
City Of Hope |
CD123-specific chimeric antigen receptor redirected T cells and methods of their use
|
TWI654206B
(zh)
|
2013-03-16 |
2019-03-21 |
諾華公司 |
使用人類化抗-cd19嵌合抗原受體治療癌症
|
DK2981607T3
(da)
|
2013-04-03 |
2020-11-16 |
Memorial Sloan Kettering Cancer Center |
Effektiv generering af tumormålrettede t-celler afledt af pluripotente stamceller
|
US9815897B2
(en)
|
2013-05-02 |
2017-11-14 |
Anaptysbio, Inc. |
Antibodies directed against programmed death-1 (PD-1)
|
CN111423511B
(zh)
|
2013-05-31 |
2024-02-23 |
索伦托药业有限公司 |
与pd-1结合的抗原结合蛋白
|
US20160122821A1
(en)
|
2013-06-10 |
2016-05-05 |
Suregene, Llc |
Genetic markers of antipsychotic response
|
AR096687A1
(es)
|
2013-06-24 |
2016-01-27 |
Genentech Inc |
Anticuerpos anti-fcrh5
|
WO2014209804A1
(en)
|
2013-06-24 |
2014-12-31 |
Biomed Valley Discoveries, Inc. |
Bispecific antibodies
|
AR097306A1
(es)
|
2013-08-20 |
2016-03-02 |
Merck Sharp & Dohme |
Modulación de la inmunidad tumoral
|
TW201605896A
(zh)
|
2013-08-30 |
2016-02-16 |
安美基股份有限公司 |
Gitr抗原結合蛋白
|
AU2014317834A1
(en)
|
2013-09-09 |
2016-03-10 |
Michael M. Abecassis |
Methods and systems for analysis of organ transplantation
|
KR102100419B1
(ko)
|
2013-09-13 |
2020-04-14 |
베이진 스위찰랜드 게엠베하 |
항-pd1 항체 및 이의 치료 및 진단 용도
|
US10927412B2
(en)
|
2013-10-01 |
2021-02-23 |
The Regents Of The University Of California |
Endometriosis classifier
|
UY35790A
(es)
|
2013-10-21 |
2015-05-29 |
Teva Pharma |
Marcadores genéticos que predicen la respuesta al acetato de glatiramer
|
WO2015061668A1
(en)
|
2013-10-25 |
2015-04-30 |
Dana-Farber Cancer Institute, Inc. |
Anti-pd-l1 monoclonal antibodies and fragments thereof
|
WO2015081158A1
(en)
|
2013-11-26 |
2015-06-04 |
Bristol-Myers Squibb Company |
Method of treating hiv by disrupting pd-1/pd-l1 signaling
|
MY184154A
(en)
|
2013-12-12 |
2021-03-23 |
Shanghai hengrui pharmaceutical co ltd |
Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof
|
SG11201604815RA
(en)
|
2013-12-19 |
2016-07-28 |
Novartis Ag |
Human mesothelin chimeric antigen receptors and uses thereof
|
JP2017509319A
(ja)
|
2014-01-15 |
2017-04-06 |
カドモン コーポレイション,リミティド ライアビリティ カンパニー |
免疫調節剤
|
WO2015109212A1
(en)
|
2014-01-17 |
2015-07-23 |
Pfizer Inc. |
Anti-il-2 antibodies and compositions and uses thereof
|
WO2015107196A1
(en)
|
2014-01-20 |
2015-07-23 |
Institut Curie |
Use of thalidomide or analogs thereof for preventing neurologic disorders induced by brain irradiation
|
CA2936244A1
(en)
|
2014-01-21 |
2015-07-30 |
Medimmune, Llc |
Compositions and methods for modulating and redirecting immune responses
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
EP3988572A1
(en)
|
2014-01-28 |
2022-04-27 |
Bristol-Myers Squibb Company |
Anti-lag-3 antibodies to treat hematological malignancies
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
RU2016137150A
(ru)
|
2014-03-13 |
2018-04-18 |
Ф. Хоффманн-Ля Рош Аг |
Способы и композиции для модулирования мутантов эстрогеновых рецепторов
|
TWI697500B
(zh)
|
2014-03-14 |
2020-07-01 |
瑞士商諾華公司 |
針對lag-3之抗體分子及其用途
|
ES2939760T3
(es)
|
2014-03-15 |
2023-04-26 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico para antígenos
|
RU2020139890A
(ru)
|
2014-04-14 |
2022-01-18 |
Арвинас Оперэйшнз, Инк. |
Имидные модуляторы протеолиза и способы их применения
|
US20160058872A1
(en)
|
2014-04-14 |
2016-03-03 |
Arvinas, Inc. |
Imide-based modulators of proteolysis and associated methods of use
|
US20180228907A1
(en)
|
2014-04-14 |
2018-08-16 |
Arvinas, Inc. |
Cereblon ligands and bifunctional compounds comprising the same
|
DK3148579T3
(da)
|
2014-05-28 |
2021-03-08 |
Agenus Inc |
Anti-gitr antistoffer og fremgangsmåder til anvendelse deraf
|
AU2015265870B2
(en)
|
2014-05-29 |
2020-07-09 |
Ventana Medical Systems, Inc. |
PD-L1 antibodies and uses thereof
|
KR101923326B1
(ko)
|
2014-06-06 |
2018-11-29 |
브리스톨-마이어스 스큅 컴퍼니 |
글루코코르티코이드-유도 종양 괴사 인자 수용체 (gitr)에 대한 항체 및 그의 용도
|
WO2015195163A1
(en)
|
2014-06-20 |
2015-12-23 |
R-Pharm Overseas, Inc. |
Pd-l1 antagonist fully human antibody
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
CN106604742B
(zh)
|
2014-07-03 |
2019-01-11 |
百济神州有限公司 |
抗pd-l1抗体及其作为治疗剂及诊断剂的用途
|
SG11201700476VA
(en)
|
2014-07-21 |
2017-02-27 |
Novartis Ag |
Treatment of cancer using humanized anti-bcma chimeric antigen receptor
|
TWI718992B
(zh)
|
2014-07-21 |
2021-02-21 |
瑞士商諾華公司 |
使用cll-1嵌合抗原受體治療癌症
|
RU2747384C2
(ru)
|
2014-07-21 |
2021-05-04 |
Новартис Аг |
Лечение рака с помощью химерного антигенного рецептора к cd33
|
AU2015292590B2
(en)
|
2014-07-24 |
2020-01-16 |
2Seventy Bio, Inc. |
BCMA chimeric antigen receptors
|
JO3663B1
(ar)
|
2014-08-19 |
2020-08-27 |
Merck Sharp & Dohme |
الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
|
TW202140557A
(zh)
|
2014-08-19 |
2021-11-01 |
瑞士商諾華公司 |
使用cd123嵌合抗原受體治療癌症
|
US10463732B2
(en)
|
2014-10-03 |
2019-11-05 |
Dana-Farber Cancer Institute, Inc. |
Glucocorticoid-induced tumor necrosis factor receptor (GITR) antibodies and methods of use thereof
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
CN114920840A
(zh)
|
2014-10-14 |
2022-08-19 |
诺华股份有限公司 |
针对pd-l1的抗体分子及其用途
|
RU2695521C9
(ru)
|
2014-10-30 |
2019-08-19 |
Канпу Биофармасьютикалс, Лтд. |
Производное изоиндолина, промежуточный продукт, способ получения, фармацевтическая композиция и ее применение
|
HUE047784T2
(hu)
|
2014-11-06 |
2020-05-28 |
Hoffmann La Roche |
Anti-TIM3 antitestek és alkalmazási eljárások
|
US20160129108A1
(en)
|
2014-11-11 |
2016-05-12 |
Medimmune Limited |
Therapeutic combinations comprising anti-cd73 antibodies and uses thereof
|
EP4112738A1
(en)
|
2014-12-05 |
2023-01-04 |
Foundation Medicine, Inc. |
Multigene analysis of tumor samples
|
TWI595006B
(zh)
|
2014-12-09 |
2017-08-11 |
禮納特神經系統科學公司 |
抗pd-1抗體類和使用彼等之方法
|
EP3034620A1
(en)
|
2014-12-17 |
2016-06-22 |
Diaxonhit |
Compositions and methods for diagnosing thyroid cancer
|
WO2016103269A1
(en)
|
2014-12-23 |
2016-06-30 |
Ramot At Tel-Aviv University Ltd. |
Populations of neural progenitor cells and methods of producing and using same
|
WO2016111947A2
(en)
|
2015-01-05 |
2016-07-14 |
Jounce Therapeutics, Inc. |
Antibodies that inhibit tim-3:lilrb2 interactions and uses thereof
|
WO2016118638A1
(en)
|
2015-01-20 |
2016-07-28 |
Merial Inc. |
Anthelmintic compounds, compositions and method of using thereof
|
EP3050570A1
(en)
|
2015-01-31 |
2016-08-03 |
Neurovision Pharma GmbH |
Pharmaceutical composition consisting of a combination of G-CSF with GM-CSF
|
WO2016140974A1
(en)
|
2015-03-01 |
2016-09-09 |
Novena Therapeutics Inc. |
Process for measuring tumor response to an initial oncology treatment
|
CA2978892A1
(en)
|
2015-03-06 |
2016-09-15 |
Sorrento Therapeutics, Inc. |
Antibody therapeutics that bind tim3
|
MA41867A
(fr)
|
2015-04-01 |
2018-02-06 |
Anaptysbio Inc |
Anticorps dirigés contre l'immunoglobuline de cellule t et protéine 3 de mucine (tim-3)
|
JP6629885B2
(ja)
|
2015-05-22 |
2020-01-15 |
バイオセリックス, インコーポレイテッド |
タンパク質を標的とする化合物、その組成物、方法、および使用
|
EP3304076A4
(en)
|
2015-06-02 |
2018-12-19 |
Celgene Corporation |
Methods for determining drug efficacy for treatment of cancer using ratios of cereblon associated proteins
|
MX2017015260A
(es)
|
2015-06-03 |
2018-02-19 |
Squibb Bristol Myers Co |
Anticuerpos anti receptor de factor de necrosis tumoral inducible por glucocorticoide (gitr) para diagnostico del cancer.
|
CA2988119A1
(en)
|
2015-06-03 |
2016-12-08 |
Dana-Farber Cancer Institute, Inc. |
Methods to induce conversion of regulatory t cells into effector t cells for cancer immunotherapy
|
EP3302572B8
(en)
|
2015-06-04 |
2021-03-24 |
Arvinas Operations, Inc. |
Imide-based modulators of proteolysis and associated methods of use
|
EP3310367A4
(en)
|
2015-06-22 |
2019-02-20 |
President and Fellows of Harvard College |
INDUCTION OF LYMPHOCYTE T REGULATORS LAMINA PROPRIA
|
KR20180031728A
(ko)
|
2015-07-23 |
2018-03-28 |
인히브릭스 엘피 |
다가 및 다중특이적 gitr 결합 융합 단백질
|
SI3334431T1
(sl)
|
2015-08-11 |
2020-01-31 |
Novartis Ag |
5-bromo-2,6-di-(1h-pirazol-l-il)pyrimidin-4-amin za uporabo v zdravljenju raka
|
EP3334758A1
(en)
|
2015-08-12 |
2018-06-20 |
Medimmune Limited |
Gitrl fusion proteins and uses thereof
|
WO2017027646A1
(en)
|
2015-08-13 |
2017-02-16 |
Merck Sharp & Dohme Corp. |
Cyclic di-nucleotide compounds as sting agonists
|
WO2017042337A1
(en)
|
2015-09-09 |
2017-03-16 |
Max-Delbrück-Centrum Für Molekulare Medizin In Der Helmhotz-Gemeinschaft |
Short-chain fatty acids for use in the treatment of cardiovascular disease
|
WO2017044979A2
(en)
|
2015-09-11 |
2017-03-16 |
Ventria Bioscience Inc. |
Lactoferrin compositions and methods for modulation of t cell subtypes and treatment of autoimmune diseases
|
US10954300B2
(en)
|
2015-09-28 |
2021-03-23 |
The Trustees Of Columbia University In The City Of New York |
Use of pentoxifylline with immune checkpoint-blockade therapies for the treatment of melanoma
|
WO2017059062A1
(en)
|
2015-09-30 |
2017-04-06 |
Theunited States Of America, As Represented By The Secretary, Department Of Health And Human Service |
Thalidomide analogs and methods of use
|
WO2017075451A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1
|
WO2017075478A2
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by use of immune cell gene signatures
|
WO2017075465A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting gata3
|
EP3384013A4
(en)
|
2015-12-04 |
2019-07-10 |
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. |
T-CELLS SPECIFIC TO ANTIGEN TO INDUCE IMMUNE TOLERANCE
|
JP7080179B2
(ja)
|
2016-03-15 |
2022-06-03 |
ザ チルドレンズ メディカル センター コーポレーション |
造血幹細胞の増大に関する方法および組成物
|
JP7001614B2
(ja)
|
2016-04-06 |
2022-02-03 |
ザ リージェンツ オブ ザ ユニヴァシティ オブ ミシガン |
リガンド依存性の標的タンパク質分解のための単官能性中間体
|
EP3452101A2
(en)
|
2016-05-04 |
2019-03-13 |
CureVac AG |
Rna encoding a therapeutic protein
|
EP3455219A4
(en)
|
2016-05-10 |
2019-12-18 |
C4 Therapeutics, Inc. |
AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR THE DEGRADATION OF TARGET PROTEINS
|
WO2017197056A1
(en)
|
2016-05-10 |
2017-11-16 |
C4 Therapeutics, Inc. |
Bromodomain targeting degronimers for target protein degradation
|
US10584101B2
(en)
|
2016-10-11 |
2020-03-10 |
Arvinas, Inc. |
Compounds and methods for the targeted degradation of androgen receptor
|
KR102570992B1
(ko)
|
2016-11-01 |
2023-08-28 |
아비나스 오퍼레이션스, 인코포레이티드 |
타우(Tau)-단백질 표적화 프로탁(PROTAC) 및 관련 사용 방법
|
IL266842B
(en)
|
2016-12-01 |
2022-09-01 |
Arvinas Operations Inc |
History of tetrahydronaphthalene and tetrahydroisoquinoline as estrogen receptor antagonists
|
BR112019012682A2
(pt)
|
2016-12-23 |
2019-12-17 |
Arvinas Operations Inc |
moléculas quiméricas visando a proteólise de egfr e métodos associados de uso
|
WO2018118598A1
(en)
|
2016-12-23 |
2018-06-28 |
Arvinas, Inc. |
Compounds and methods for the targeted degradation of fetal liver kinase polypeptides
|
US10723717B2
(en)
|
2016-12-23 |
2020-07-28 |
Arvinas Operations, Inc. |
Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides
|
US11191741B2
(en)
|
2016-12-24 |
2021-12-07 |
Arvinas Operations, Inc. |
Compounds and methods for the targeted degradation of enhancer of zeste homolog 2 polypeptide
|
JP7266526B6
(ja)
|
2017-01-26 |
2024-02-15 |
アルビナス・オペレーションズ・インコーポレイテッド |
エストロゲン受容体タンパク質分解性の調節因子およびその関連方法
|
BR112019015484A2
(pt)
|
2017-01-31 |
2020-04-28 |
Arvinas Operations Inc |
ligantes de cereblon e compostos bifuncionais compreendendo os mesmos
|
CN106932576A
(zh)
|
2017-03-22 |
2017-07-07 |
山东大学深圳研究院 |
一种人调节性t细胞的免疫抑制功能的检测方法
|
TWI793151B
(zh)
*
|
2017-08-23 |
2023-02-21 |
瑞士商諾華公司 |
3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途
|
TWI829655B
(zh)
*
|
2017-10-18 |
2024-01-21 |
瑞士商諾華公司 |
用於選擇性蛋白質降解的組合物及方法
|
KR20210018199A
(ko)
*
|
2018-03-26 |
2021-02-17 |
씨4 테라퓨틱스, 인코포레이티드 |
이카로스의 분해를 위한 세레블론 결합제
|
JP2021524484A
(ja)
|
2018-07-10 |
2021-09-13 |
ノバルティス アーゲー |
3−(5−ヒドロキシ−1−オキソイソインドリン−2−イル)ピペリジン−2,6−ジオン誘導体及びIkarosファミリージンクフィンガー2(IKZF2)依存性疾患の処置におけるその使用
|