SI3317301T1 - Kombinirane terapije, ki obsegajo molekule protitelesa na LAG-3 - Google Patents

Kombinirane terapije, ki obsegajo molekule protitelesa na LAG-3

Info

Publication number
SI3317301T1
SI3317301T1 SI201631247T SI201631247T SI3317301T1 SI 3317301 T1 SI3317301 T1 SI 3317301T1 SI 201631247 T SI201631247 T SI 201631247T SI 201631247 T SI201631247 T SI 201631247T SI 3317301 T1 SI3317301 T1 SI 3317301T1
Authority
SI
Slovenia
Prior art keywords
lag
antibody molecules
combination therapies
therapies
combination
Prior art date
Application number
SI201631247T
Other languages
English (en)
Inventor
Glenn Dranoff
Frederic Triebel
Chrystlle Brignone
Walter A Blattler
Jennifer Marie Mataraza
Catherine Anne Sabatos-Peyton
Hwai Wen Chang
Johann Gerhard
Original Assignee
Novartis Ag
Immutep Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Immutep Sas filed Critical Novartis Ag
Publication of SI3317301T1 publication Critical patent/SI3317301T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI201631247T 2015-07-29 2016-07-28 Kombinirane terapije, ki obsegajo molekule protitelesa na LAG-3 SI3317301T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562198492P 2015-07-29 2015-07-29
EP16757391.4A EP3317301B1 (en) 2015-07-29 2016-07-28 Combination therapies comprising antibody molecules to lag-3
PCT/US2016/044545 WO2017019894A1 (en) 2015-07-29 2016-07-28 Combination therapies comprising antibody molecules to lag-3

Publications (1)

Publication Number Publication Date
SI3317301T1 true SI3317301T1 (sl) 2021-10-29

Family

ID=56801779

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201631247T SI3317301T1 (sl) 2015-07-29 2016-07-28 Kombinirane terapije, ki obsegajo molekule protitelesa na LAG-3

Country Status (12)

Country Link
US (2) US20180340025A1 (sl)
EP (2) EP3317301B1 (sl)
CY (1) CY1124299T1 (sl)
DK (1) DK3317301T3 (sl)
ES (1) ES2878188T3 (sl)
HR (1) HRP20211058T8 (sl)
HU (1) HUE055469T2 (sl)
LT (1) LT3317301T (sl)
PL (1) PL3317301T3 (sl)
PT (1) PT3317301T (sl)
SI (1) SI3317301T1 (sl)
WO (1) WO2017019894A1 (sl)

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