US7744877B2
(en)
|
1992-11-13 |
2010-06-29 |
Biogen Idec Inc. |
Expression and use of anti-CD20 Antibodies
|
CA2149329C
(en)
|
1992-11-13 |
2008-07-15 |
Darrell R. Anderson |
Therapeutic application of chimeric and radiolabeled antibodies to human b lymphocyte restricted differentiation antigen for treatment of b cell lymphoma
|
EP1112084B2
(en)
|
1998-08-11 |
2012-04-25 |
Biogen Idec Inc. |
Combination therapies for b-cell lymphomas comprising administration of anti-cd20 antibody
|
MY155913A
(en)
*
|
1998-11-09 |
2015-12-15 |
Biogen Inc |
Chimeric anti-cd20 antibody treatment of patients receiving bmt or pbsc transpants
|
WO2000027428A1
(en)
|
1998-11-09 |
2000-05-18 |
Idec Pharmaceuticals Corporation |
Treatment of hematologic malignancies associated with circulating tumor cells using chimeric anti-cd20 antibody
|
US7183387B1
(en)
|
1999-01-15 |
2007-02-27 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
WO2000067796A1
(en)
|
1999-05-07 |
2000-11-16 |
Genentech, Inc. |
Treatment of autoimmune diseases with antagonists which bind to b cell surface markers
|
JP2003528805A
(ja)
*
|
1999-07-12 |
2003-09-30 |
ジェネンテック・インコーポレーテッド |
Cd20に結合するアンタゴニストを用いた異種抗原に対する免疫応答のブロッキング
|
US8557244B1
(en)
|
1999-08-11 |
2013-10-15 |
Biogen Idec Inc. |
Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody
|
CA2422076A1
(en)
*
|
2000-09-18 |
2002-03-21 |
Idec Pharmaceutical Corporation |
Combination therapy for treatment of autoimmune diseases using b cell depleting/immunoregulatory antibody combination
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
ES2326964T3
(es)
*
|
2001-10-25 |
2009-10-22 |
Genentech, Inc. |
Composiciones de glicoproteina.
|
US8188231B2
(en)
|
2002-09-27 |
2012-05-29 |
Xencor, Inc. |
Optimized FC variants
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
US7662925B2
(en)
|
2002-03-01 |
2010-02-16 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
EP1495055B1
(en)
*
|
2002-04-18 |
2013-08-14 |
Genencor International, Inc. |
Production of functional antibodies in filamentous fungi
|
DE60332957D1
(de)
*
|
2002-12-16 |
2010-07-22 |
Genentech Inc |
Immunoglobulinvarianten und deren verwendungen
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
US8084582B2
(en)
|
2003-03-03 |
2011-12-27 |
Xencor, Inc. |
Optimized anti-CD20 monoclonal antibodies having Fc variants
|
US8388955B2
(en)
|
2003-03-03 |
2013-03-05 |
Xencor, Inc. |
Fc variants
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
ES2322267T3
(es)
*
|
2003-04-09 |
2009-06-18 |
Genentech, Inc. |
Terapia de una enfermedad autoinmunologica en un paciente que presenta una respuesta inadecuada a un inhibidor de tnf-alfa.
|
US9051373B2
(en)
|
2003-05-02 |
2015-06-09 |
Xencor, Inc. |
Optimized Fc variants
|
KR20060027801A
(ko)
*
|
2003-06-05 |
2006-03-28 |
제넨테크, 인크. |
B 세포 장애에 대한 조합 요법
|
US9714282B2
(en)
|
2003-09-26 |
2017-07-25 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
US8883147B2
(en)
|
2004-10-21 |
2014-11-11 |
Xencor, Inc. |
Immunoglobulins insertions, deletions, and substitutions
|
EA036531B1
(ru)
|
2003-11-05 |
2020-11-19 |
Роше Гликарт Аг |
Гуманизированное антитело типа ii к cd20 (варианты), фармацевтическая композиция, содержащая эти варианты антитела, и их применение
|
WO2005063815A2
(en)
*
|
2003-11-12 |
2005-07-14 |
Biogen Idec Ma Inc. |
Fcϝ receptor-binding polypeptide variants and methods related thereto
|
AR049292A1
(es)
*
|
2004-06-04 |
2006-07-12 |
Genentech Inc |
Metodo para tratar lupus con un anticuerpo cd20
|
US20060051345A1
(en)
*
|
2004-06-04 |
2006-03-09 |
Genentech, Inc. |
Method for treating multiple sclerosis
|
EP1773391A4
(en)
*
|
2004-06-25 |
2009-01-21 |
Medimmune Inc |
INCREASING THE PRODUCTION OF RECOMBINANT ANTIBODIES IN MAMMALIAN CELLS BY MUTAGENESIS ON THE SITE
|
WO2006085967A2
(en)
*
|
2004-07-09 |
2006-08-17 |
Xencor, Inc. |
OPTIMIZED ANTI-CD20 MONOCONAL ANTIBODIES HAVING Fc VARIANTS
|
US20150010550A1
(en)
|
2004-07-15 |
2015-01-08 |
Xencor, Inc. |
OPTIMIZED Fc VARIANTS
|
BRPI0513100A
(pt)
*
|
2004-07-22 |
2007-10-23 |
Genentech Inc |
métodos de tratamento da sìndrome de sjÍgren e artigos manufaturados
|
EA012464B1
(ru)
|
2004-08-04 |
2009-10-30 |
Эпплайд Молекьюлар Эволюшн, Инк. |
Антитело против cd20 и его применение
|
CA2577133A1
(en)
*
|
2004-08-19 |
2006-03-23 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
WO2006041680A2
(en)
|
2004-10-05 |
2006-04-20 |
Genentech, Inc. |
Method for treating vasculitis
|
AR052774A1
(es)
*
|
2004-10-08 |
2007-04-04 |
Wyeth Corp |
Inmunoterapia para trastornos autoinmunes
|
JO3000B1
(ar)
*
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
US8546543B2
(en)
|
2004-11-12 |
2013-10-01 |
Xencor, Inc. |
Fc variants that extend antibody half-life
|
CN102746404B
(zh)
|
2004-11-12 |
2016-01-20 |
赞科股份有限公司 |
对FcRn的结合被改变的Fc变体
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
FR2879204B1
(fr)
|
2004-12-15 |
2007-02-16 |
Lab Francais Du Fractionnement |
Anticorps cytotoxique dirige contre les proliferations hematopoietiques lymphoides de type b.
|
ES2557325T5
(es)
|
2004-12-28 |
2023-11-15 |
Innate Pharma Sa |
Anticuerpos monoclonales contra NKG2A
|
GT200600020A
(es)
*
|
2005-01-13 |
2006-11-08 |
|
Procedimiento de tratamiento
|
DOP2006000029A
(es)
*
|
2005-02-07 |
2006-08-15 |
Genentech Inc |
Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas)
|
TW200714289A
(en)
*
|
2005-02-28 |
2007-04-16 |
Genentech Inc |
Treatment of bone disorders
|
AR053579A1
(es)
*
|
2005-04-15 |
2007-05-09 |
Genentech Inc |
Tratamiento de la enfermedad inflamatoria intestinal (eii)
|
US20090215639A1
(en)
*
|
2005-04-26 |
2009-08-27 |
Bioren, Inc. |
Method of Producing Human IgG Antibodies with Enhanced Effector Functions
|
CN101282993A
(zh)
*
|
2005-06-02 |
2008-10-08 |
阿斯利康公司 |
针对cd20的抗体和其用途
|
DK1912675T3
(en)
|
2005-07-25 |
2014-03-24 |
Emergent Product Dev Seattle |
B-cell reduction using specific and cd37-cd20-specific binding molecules
|
US20090226440A1
(en)
*
|
2005-08-12 |
2009-09-10 |
Shane Grey |
Prophylactic and/or Therapeutic Method for Treatment of Autoimmune Disease
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
EP1931709B1
(en)
|
2005-10-03 |
2016-12-07 |
Xencor, Inc. |
Fc variants with optimized fc receptor binding properties
|
CA2625998C
(en)
|
2005-10-06 |
2015-12-01 |
Xencor, Inc. |
Optimized anti-cd30 antibodies
|
AU2006301492B2
(en)
*
|
2005-10-11 |
2011-06-09 |
Amgen Research (Munich) Gmbh |
Compositions comprising cross-species-specific antibodies and uses thereof
|
MY149159A
(en)
|
2005-11-15 |
2013-07-31 |
Hoffmann La Roche |
Method for treating joint damage
|
CA2629306A1
(en)
|
2005-11-23 |
2007-05-31 |
Genentech, Inc. |
Methods and compositions related to b cell assays
|
CN105859886A
(zh)
|
2005-12-02 |
2016-08-17 |
健泰科生物技术公司 |
牵涉与il-22和il-22r结合的抗体的组合物和方法
|
RU2450020C2
(ru)
|
2006-01-05 |
2012-05-10 |
Дженентек, Инк. |
АНТИТЕЛА ПРОТИВ EphB4 И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
|
KR101617108B1
(ko)
|
2006-01-20 |
2016-04-29 |
제넨테크, 인크. |
항-ephrinb2 항체 및 그의 사용 방법
|
AR059851A1
(es)
|
2006-03-16 |
2008-04-30 |
Genentech Inc |
Anticuerpos de la egfl7 y metodos de uso
|
AR060978A1
(es)
|
2006-05-30 |
2008-07-23 |
Genentech Inc |
Anticuerpos e inmunoconjugados y sus usos
|
AU2007319672B2
(en)
|
2006-06-06 |
2011-06-30 |
Genentech, Inc. |
Anti-DLL4 antibodies and methods using same
|
FR2902799B1
(fr)
|
2006-06-27 |
2012-10-26 |
Millipore Corp |
Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
|
RU2499001C2
(ru)
|
2006-06-30 |
2013-11-20 |
Ново Нордиск А/С |
Антитела к nkg2a и их применения
|
EP2046383B1
(en)
|
2006-07-04 |
2014-11-19 |
Genmab A/S |
Cd20 binding molecules for the treatment of copd
|
EP1878747A1
(en)
|
2006-07-11 |
2008-01-16 |
greenovation Biotech GmbH |
Glyco-engineered antibodies
|
US20100166741A1
(en)
*
|
2006-07-13 |
2010-07-01 |
Genentech , Inc. |
Altered br-3 binding polypeptides
|
ES2612383T3
(es)
|
2006-07-19 |
2017-05-16 |
The Trustees Of The University Of Pennsylvania |
WSX-1/IL-27 como una diana para respuestas antiinflamatorias
|
DK2383297T5
(da)
|
2006-08-14 |
2022-07-04 |
Xencor Inc |
Optimerede antistoffer rettet mod CD19
|
WO2008034076A2
(en)
*
|
2006-09-15 |
2008-03-20 |
The Johns Hopkins University |
Cyclophosphamide in combination with immune therapeutics
|
WO2008036688A2
(en)
|
2006-09-18 |
2008-03-27 |
Xencor, Inc. |
Optimized antibodies that target hm1.24
|
MX2009003774A
(es)
|
2006-10-12 |
2009-04-22 |
Genentech Inc |
Anticuerpos para linfotoxina-alfa.
|
SI2502938T1
(sl)
|
2006-10-27 |
2015-05-29 |
Genentech, Inc. |
Protitelesa in imunokonjugati in njihove uporabe
|
WO2008069999A2
(en)
|
2006-12-01 |
2008-06-12 |
Selexys Pharmaceuticals Corporation |
Anti-p-selectin antibodies and methods of using the same to treat inflammatory diseases
|
US8362217B2
(en)
|
2006-12-21 |
2013-01-29 |
Emd Millipore Corporation |
Purification of proteins
|
US8569464B2
(en)
|
2006-12-21 |
2013-10-29 |
Emd Millipore Corporation |
Purification of proteins
|
WO2008079280A1
(en)
|
2006-12-21 |
2008-07-03 |
Millipore Corporation |
Purification of proteins
|
ES2426158T3
(es)
|
2007-01-22 |
2013-10-21 |
Genentech, Inc. |
Precipitación con polielectrolito y purificación de anticuerpos
|
CA2676766A1
(en)
|
2007-02-09 |
2008-08-21 |
Genentech, Inc. |
Anti-robo4 antibodies and uses therefor
|
US7960139B2
(en)
|
2007-03-23 |
2011-06-14 |
Academia Sinica |
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
|
PE20090321A1
(es)
|
2007-06-04 |
2009-04-20 |
Genentech Inc |
Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica
|
NZ581468A
(en)
*
|
2007-06-25 |
2012-09-28 |
Esbatech Alcon Biomed Res Unit |
Methods of modifying antibodies, and modified antibodies with improved functional properties
|
SG188136A1
(en)
|
2007-09-13 |
2013-03-28 |
Delenex Therapeutics Ag |
HUMANIZED ANTIBODIES AGAINST THE ß-AMYLOYD PEPTIDE
|
GB0718684D0
(en)
*
|
2007-09-24 |
2007-10-31 |
Roche Products Ltd |
Treatment method
|
CL2008002886A1
(es)
|
2007-09-26 |
2009-12-04 |
Chugai Pharmaceutical Co Ltd |
Region constante de un anticuerpo humano; anticuerpo anti-receptor de interleucina-6 (il-6) y composicion farmaceutica que la comprende.
|
US20090098118A1
(en)
|
2007-10-15 |
2009-04-16 |
Thomas Friess |
Combination therapy of a type ii anti-cd20 antibody with an anti-bcl-2 active agent
|
WO2009051974A1
(en)
*
|
2007-10-17 |
2009-04-23 |
Nuvelo, Inc. |
Antibodes to cll-1
|
RS53850B2
(sr)
|
2007-10-30 |
2018-07-31 |
Genentech Inc |
Pročišćavanje antitela hromatografijom izmene katjona
|
SI2514436T1
(en)
|
2007-11-07 |
2018-04-30 |
Genentech, Inc. |
IL-22 for use in the treatment of microbial diseases
|
AR069501A1
(es)
|
2007-11-30 |
2010-01-27 |
Genentech Inc |
Anticuerpos anti- vegf (factor de crecimiento endotelial vascular)
|
SI2808343T1
(sl)
|
2007-12-26 |
2019-10-30 |
Xencor Inc |
Fc-variante s spremenjeno vezavo na FcRn
|
EP2247619A1
(en)
*
|
2008-01-24 |
2010-11-10 |
Novo Nordisk A/S |
Humanized anti-human nkg2a monoclonal antibody
|
TWI489994B
(zh)
|
2008-03-17 |
2015-07-01 |
Baxter Healthcare Sa |
供免疫球蛋白及玻尿酸酶之皮下投藥之用的組合及方法
|
AR072947A1
(es)
*
|
2008-03-25 |
2010-10-06 |
Glycart Biotechnology Ag |
Terapia de combinacion de un anticuerpo anti-cd20 de tipo ii con citotoxicidad, celular dependiente de anticuerpos (ccda) aumentada, composicion farmaceutica, anticuerpo anti-cd20 de tipo ii
|
ES2368700T3
(es)
|
2008-04-11 |
2011-11-21 |
Emergent Product Development Seattle, Llc |
Agente inmunoterapéutico para cd37 y combinación con un agente quimioterapéutico bifuncional del mismo.
|
US20100260668A1
(en)
*
|
2008-04-29 |
2010-10-14 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
SG190572A1
(en)
*
|
2008-04-29 |
2013-06-28 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
CA2726087A1
(en)
*
|
2008-06-03 |
2009-12-10 |
Tariq Ghayur |
Dual variable domain immunoglobulins and uses thereof
|
RU2010153578A
(ru)
*
|
2008-06-03 |
2012-07-20 |
Эбботт Лэборетриз (Us) |
Иммуноглобулины с двойными вариабельными доменами и их применение
|
US8999702B2
(en)
|
2008-06-11 |
2015-04-07 |
Emd Millipore Corporation |
Stirred tank bioreactor
|
RU2011104348A
(ru)
*
|
2008-07-08 |
2012-08-20 |
Эбботт Лэборетриз (Us) |
Иммуноглобулины с двойным вариабельным доменом против простагландина е2 и их применение
|
JP5986745B2
(ja)
|
2008-07-15 |
2016-09-06 |
アカデミア シニカAcademia Sinica |
Ptfe様のアルミニウム・コート・ガラススライド上のグリカンアレイおよび関連する方法
|
HUE047316T2
(hu)
|
2008-08-14 |
2020-04-28 |
Genentech Inc |
Eljárások szennyezés eltávolítására indigén fehérjekiszorításos ioncserés membrán kromatográfia alkalmazásával
|
JP5705115B2
(ja)
|
2008-09-10 |
2015-04-22 |
ジェネンテック, インコーポレイテッド |
蛋白質の酸化的分解の予防のための組成物および方法
|
TW201014605A
(en)
*
|
2008-09-16 |
2010-04-16 |
Genentech Inc |
Methods for treating progressive multiple sclerosis
|
KR20190025057A
(ko)
|
2008-10-14 |
2019-03-08 |
제넨테크, 인크. |
이뮤노글로불린 변이체 및 그의 용도
|
JP2012509270A
(ja)
*
|
2008-11-17 |
2012-04-19 |
ジェネンテック, インコーポレイテッド |
生理的条件下での高分子の凝集を低減するための方法及び製剤
|
KR101546563B1
(ko)
|
2008-12-09 |
2015-08-28 |
할로자임, 아이엔씨 |
연장된 가용성 ph20 폴리펩티드 및 그의 용도
|
CN105037535A
(zh)
|
2008-12-16 |
2015-11-11 |
Emd密理博公司 |
搅拌槽反应器及方法
|
KR20110101212A
(ko)
|
2008-12-17 |
2011-09-15 |
제넨테크, 인크. |
C형 간염 바이러스 조합 요법
|
WO2010075249A2
(en)
|
2008-12-22 |
2010-07-01 |
Genentech, Inc. |
A method for treating rheumatoid arthritis with b-cell antagonists
|
MX2011006870A
(es)
|
2008-12-23 |
2011-07-19 |
Genentech Inc |
Variantes de inmunoglobulina con union alterada a proteina a.
|
AU2010214082A1
(en)
*
|
2009-02-16 |
2011-10-13 |
Synthon Biopharmaceuticals B.V. |
Humanized anti-CD20 antibodies and methods of use
|
US8435488B2
(en)
|
2009-02-27 |
2013-05-07 |
Genentech, Inc. |
Methods and compositions for protein labelling
|
ES2572728T3
(es)
|
2009-03-20 |
2016-06-02 |
F. Hoffmann-La Roche Ag |
Anticuerpos anti-HER biespecíficos
|
NZ594343A
(en)
|
2009-03-25 |
2013-10-25 |
Genentech Inc |
Novel anti-alpha5beta1 antibodies and uses thereof
|
CA2754163C
(en)
|
2009-03-25 |
2019-04-09 |
Genentech, Inc. |
Anti-fgfr3 antibodies and methods using same
|
AR075982A1
(es)
|
2009-03-31 |
2011-05-11 |
Roche Glycart Ag |
Terapia de combinacion de un anticuerpo afucosilado y una o mas de las citoquinas seleccionadas de gm- csf humano, m -csf humano y/o il-3 humano y composicion
|
US9309325B2
(en)
|
2009-05-07 |
2016-04-12 |
The Regents Of The University Of California |
Antibodies and methods of use thereof
|
AU2010248938B2
(en)
*
|
2009-05-13 |
2014-12-11 |
Gliknik Inc. |
Methods of using immunoglobulin aggregates
|
US8815242B2
(en)
*
|
2009-05-27 |
2014-08-26 |
Synageva Biopharma Corp. |
Avian derived antibodies
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
US20100316639A1
(en)
|
2009-06-16 |
2010-12-16 |
Genentech, Inc. |
Biomarkers for igf-1r inhibitor therapy
|
TW201106972A
(en)
|
2009-07-27 |
2011-03-01 |
Genentech Inc |
Combination treatments
|
UY32808A
(es)
*
|
2009-07-29 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas como dominio variable dual y usos de las mismas
|
NZ597531A
(en)
|
2009-07-31 |
2014-05-30 |
Genentech Inc |
Inhibition of tumor metastasis using bv8- or g-csf-antagonists
|
TWI409079B
(zh)
|
2009-08-14 |
2013-09-21 |
Roche Glycart Ag |
非典型岩藻醣化cd20抗體與苯達莫斯汀(bendamustine)之組合療法
|
AU2010281867A1
(en)
|
2009-08-14 |
2012-02-02 |
Roche Glycart Ag |
Combination therapy of an afucosylated CD20 antibody with fludarabine and/or mitoxantrone
|
KR20120060877A
(ko)
*
|
2009-09-01 |
2012-06-12 |
아보트 러보러터리즈 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
US9321823B2
(en)
|
2009-09-02 |
2016-04-26 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
EP3211094A3
(en)
|
2009-09-03 |
2017-11-01 |
F. Hoffmann-La Roche AG |
Methods for treating, diagnosing, and monitoring rheumatoid arthritis
|
AR078161A1
(es)
|
2009-09-11 |
2011-10-19 |
Hoffmann La Roche |
Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento.
|
CA2774260C
(en)
|
2009-09-16 |
2018-10-09 |
Immunomedics, Inc. |
Class i anti-cea antibodies and uses thereof
|
IN2012DN03219A
(zh)
|
2009-09-17 |
2015-10-23 |
Baxter Healthcare Sa |
|
AU2010306677B2
(en)
*
|
2009-10-15 |
2013-05-23 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
NZ599337A
(en)
|
2009-10-22 |
2013-05-31 |
Genentech Inc |
Anti-hepsin antibodies and methods using same
|
WO2011056497A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor type iib compositions and methods of use
|
WO2011056502A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Bone morphogenetic protein receptor type ii compositions and methods of use
|
WO2011056494A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor-like kinase-1 antagonist and vegfr3 antagonist combinations
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
AU2010315101B2
(en)
|
2009-11-04 |
2016-01-28 |
Fabrus Llc |
Methods for affinity maturation-based antibody optimization
|
RU2585488C2
(ru)
|
2009-11-05 |
2016-05-27 |
Дженентек, Инк. |
Способы и композиция для секреции гетерологичных полипептидов
|
CN102711829B
(zh)
*
|
2009-11-30 |
2016-03-16 |
生物测试股份公司 |
治疗***性红斑狼疮(sle)的人源化抗il-10抗体
|
US11377485B2
(en)
|
2009-12-02 |
2022-07-05 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
WO2011068993A1
(en)
|
2009-12-02 |
2011-06-09 |
Acceleron Pharma Inc. |
Compositions and methods for increasing serum half-life of fc fusion proteins.
|
US10087236B2
(en)
|
2009-12-02 |
2018-10-02 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
TWI505836B
(zh)
|
2009-12-11 |
2015-11-01 |
Genentech Inc |
抗-vegf-c抗體及其使用方法
|
SI2516465T1
(sl)
|
2009-12-23 |
2016-08-31 |
F. Hoffmann-La Roche Ag |
Protelesa proti bv8 in uporaba le-teh
|
US8362210B2
(en)
|
2010-01-19 |
2013-01-29 |
Xencor, Inc. |
Antibody variants with enhanced complement activity
|
CN102933231B
(zh)
|
2010-02-10 |
2015-07-29 |
伊缪诺金公司 |
Cd20抗体及其用途
|
JP5981853B2
(ja)
|
2010-02-18 |
2016-08-31 |
ジェネンテック, インコーポレイテッド |
ニューレグリンアンタゴニスト及び癌の治療におけるそれらの使用
|
WO2011101328A2
(en)
|
2010-02-18 |
2011-08-25 |
Roche Glycart Ag |
Treatment with a humanized igg class anti egfr antibody and an antibody against insulin like growth factor 1 receptor
|
PL2550018T3
(pl)
|
2010-03-22 |
2019-08-30 |
F.Hoffmann-La Roche Ag |
Kompozycje i sposoby użyteczne do stabilizowania preparatów zawierających białko
|
NZ602040A
(en)
|
2010-03-24 |
2014-12-24 |
Genentech Inc |
Anti-lrp6 antibodies
|
WO2011130332A1
(en)
|
2010-04-12 |
2011-10-20 |
Academia Sinica |
Glycan arrays for high throughput screening of viruses
|
CA2795544A1
(en)
|
2010-04-27 |
2011-11-03 |
Roche Glycart Ag |
Combination therapy of an afucosylated cd20 antibody with a mtor inhibitor
|
EP2566510A1
(en)
|
2010-05-03 |
2013-03-13 |
F. Hoffmann-La Roche AG |
Compositions and methods useful for reducing the viscosity of protein-containing formulations
|
CA2835489C
(en)
|
2010-05-10 |
2018-03-06 |
Chi-Huey Wong |
Zanamivir phosphonate congeners with anti-influenza activity and determining oseltamivir susceptibility of influenza viruses
|
SI2571532T1
(sl)
|
2010-05-14 |
2017-10-30 |
Abbvie Inc. |
Proteini, ki vežejo IL-1
|
EP2571903B1
(en)
|
2010-05-17 |
2019-09-04 |
EMD Millipore Corporation |
Stimulus responsive polymers for the purification of biomolecules
|
WO2011147834A1
(en)
|
2010-05-26 |
2011-12-01 |
Roche Glycart Ag |
Antibodies against cd19 and uses thereof
|
BR112012029866A2
(pt)
|
2010-06-03 |
2017-03-07 |
Genentech Inc |
método para a determinação da presença de uma proteína steap-1
|
RU2577986C2
(ru)
|
2010-06-18 |
2016-03-20 |
Дженентек, Инк. |
Антитела против axl и способы их применения
|
WO2011161119A1
(en)
|
2010-06-22 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Antibodies against insulin-like growth factor i receptor and uses thereof
|
CA2802756C
(en)
|
2010-06-24 |
2021-05-04 |
Genentech, Inc. |
Compositions and methods for stabilizing protein-containing formulations
|
WO2011161189A1
(en)
|
2010-06-24 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Anti-hepsin antibodies and methods of use
|
NZ605449A
(en)
|
2010-07-09 |
2015-03-27 |
Genentech Inc |
Anti-neuropilin antibodies and methods of use
|
WO2012010582A1
(en)
|
2010-07-21 |
2012-01-26 |
Roche Glycart Ag |
Anti-cxcr5 antibodies and methods of use
|
JP5953303B2
(ja)
|
2010-07-29 |
2016-07-20 |
ゼンコア インコーポレイテッド |
改変された等電点を有する抗体
|
KR20130100118A
(ko)
|
2010-08-03 |
2013-09-09 |
아비에 인코포레이티드 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
CN103153341B
(zh)
|
2010-08-03 |
2015-05-27 |
霍夫曼-拉罗奇有限公司 |
慢性淋巴细胞性白血病(cll)生物标志物
|
CA2805564A1
(en)
|
2010-08-05 |
2012-02-09 |
Stefan Jenewein |
Anti-mhc antibody anti-viral cytokine fusion protein
|
EP3578205A1
(en)
|
2010-08-06 |
2019-12-11 |
ModernaTX, Inc. |
A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof
|
BR112013002444A2
(pt)
|
2010-08-13 |
2016-05-24 |
Roche Glycart Ag |
anticorpo, polinucleotídeo e polipeotídeo isolados, composição, vetor, cécula hospedeira, conjulgado de anticorpo, formulação farmacêutica, uso do anticorpo, métodos para produzir um anticorpo, tratar um indivíduo, induzir a lise celular de uma célula tumorosa e diagnosticar uma doença em um indivíduo
|
SG187746A1
(en)
|
2010-08-13 |
2013-03-28 |
Roche Glycart Ag |
Anti-fap antibodies and methods of use
|
TW201208703A
(en)
|
2010-08-17 |
2012-03-01 |
Roche Glycart Ag |
Combination therapy of an afucosylated CD20 antibody with an anti-VEGF antibody
|
CA2805054A1
(en)
|
2010-08-25 |
2012-03-01 |
F. Hoffmann-La Roche Ag |
Antibodies against il-18r1 and uses thereof
|
CA2809433A1
(en)
|
2010-08-26 |
2012-03-01 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
SG10201408229WA
(en)
|
2010-08-31 |
2015-02-27 |
Genentech Inc |
Biomarkers and methods of treatment
|
US20120237975A1
(en)
|
2010-10-01 |
2012-09-20 |
Jason Schrum |
Engineered nucleic acids and methods of use thereof
|
WO2012047968A2
(en)
|
2010-10-05 |
2012-04-12 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
EP3351559A3
(en)
|
2010-11-08 |
2018-10-31 |
F. Hoffmann-La Roche AG |
Subcutaneously administered anti-il-6 receptor antibody
|
WO2012064836A1
(en)
|
2010-11-10 |
2012-05-18 |
Genentech, Inc. |
Methods and compositions for neural disease immunotherapy
|
AU2011343570B2
(en)
|
2010-12-16 |
2016-11-03 |
Genentech, Inc. |
Diagnosis and treatments relating to TH2 inhibition
|
CA2819436A1
(en)
|
2010-12-16 |
2012-06-21 |
Roche Glycart Ag |
Combination therapy of an afucosylated cd20 antibody with a mdm2 inhibitor
|
MX345519B
(es)
|
2010-12-20 |
2017-02-01 |
Genentech Inc |
Anticuerpos anti-mesotelina e inmunoconjugados.
|
MA34818B1
(fr)
|
2010-12-22 |
2014-01-02 |
Genentech Inc |
Anticorps anti-pcsk9 et procédés d'utilisation
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
EP2482074A1
(en)
*
|
2011-01-27 |
2012-08-01 |
Medizinische Hochschule Hannover |
Methods and means for diagnosing vasculitis
|
US10689447B2
(en)
|
2011-02-04 |
2020-06-23 |
Genentech, Inc. |
Fc variants and methods for their production
|
CA2824252A1
(en)
|
2011-02-10 |
2012-08-16 |
Roche Glycart Ag |
Improved immunotherapy
|
CN103403025B
(zh)
|
2011-02-28 |
2016-10-12 |
弗·哈夫曼-拉罗切有限公司 |
单价抗原结合蛋白
|
KR20140022815A
(ko)
|
2011-02-28 |
2014-02-25 |
제넨테크, 인크. |
B-세포 길항제에 대한 반응을 예측하기 위한 생물학적 마커 및 방법
|
ES2549638T3
(es)
|
2011-02-28 |
2015-10-30 |
F. Hoffmann-La Roche Ag |
Proteínas de unión a antígeno
|
US20120222851A1
(en)
*
|
2011-03-04 |
2012-09-06 |
GM Global Technology Operations LLC |
Hvac system damper
|
PT2691417T
(pt)
|
2011-03-29 |
2018-10-31 |
Roche Glycart Ag |
Variantes de fc de anticorpos
|
EP2691101A2
(en)
|
2011-03-31 |
2014-02-05 |
Moderna Therapeutics, Inc. |
Delivery and formulation of engineered nucleic acids
|
JP2014516511A
(ja)
|
2011-04-07 |
2014-07-17 |
ジェネンテック, インコーポレイテッド |
抗fgfr4抗体及び使用方法
|
WO2012146630A1
(en)
|
2011-04-29 |
2012-11-01 |
F. Hoffmann-La Roche Ag |
N-terminal acylated polypeptides, methods for their production and uses thereof
|
EA201892619A1
(ru)
|
2011-04-29 |
2019-04-30 |
Роше Гликарт Аг |
Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2
|
JP5987053B2
(ja)
|
2011-05-12 |
2016-09-06 |
ジェネンテック, インコーポレイテッド |
フレームワークシグネチャーペプチドを用いて動物サンプルにおける治療抗体を検出するための多重反応モニタリングlc−ms/ms法
|
WO2012158704A1
(en)
|
2011-05-16 |
2012-11-22 |
Genentech, Inc. |
Fgfr1 agonists and methods of use
|
SG195072A1
(en)
|
2011-05-21 |
2013-12-30 |
Macrogenics Inc |
Cd3-binding molecules capable of binding to human and non-human cd3
|
AR086924A1
(es)
|
2011-06-15 |
2014-01-29 |
Hoffmann La Roche |
Anticuerpos anti-receptor de epo humano y los metodos para su utilizacion
|
AU2012268939B2
(en)
|
2011-06-17 |
2017-05-04 |
Novo Nordisk A/S |
Selective elimination of erosive cells
|
SG195077A1
(en)
|
2011-06-22 |
2013-12-30 |
Hoffmann La Roche |
Removal of target cells by circulating virus-specific cytotoxic t-cells using mhc class i comprising complexes
|
WO2013003680A1
(en)
|
2011-06-30 |
2013-01-03 |
Genentech, Inc. |
Anti-c-met antibody formulations
|
MX2014001766A
(es)
|
2011-08-17 |
2014-05-01 |
Genentech Inc |
Anticuerpos de neuregulina y sus usos.
|
CN103890008A
(zh)
|
2011-08-17 |
2014-06-25 |
霍夫曼-拉罗奇有限公司 |
在顽固性肿瘤中抑制血管发生
|
SI2748202T1
(sl)
|
2011-08-23 |
2018-10-30 |
Roche Glycart Ag |
Bispecifične molekule, ki se vežejo na antigen
|
US9309306B2
(en)
|
2011-08-23 |
2016-04-12 |
Roche Glycart Ag |
Anti-MCSP antibodies
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
KR20140068062A
(ko)
|
2011-09-15 |
2014-06-05 |
제넨테크, 인크. |
분화의 촉진 방법
|
MX2014002990A
(es)
|
2011-09-19 |
2014-05-21 |
Genentech Inc |
Tratamientos combinados que comprenden antagonistas de c-met y antagonistas de b-raf.
|
CA2850624A1
(en)
|
2011-10-03 |
2013-04-11 |
Moderna Therapeutics, Inc. |
Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
|
US9663573B2
(en)
|
2011-10-05 |
2017-05-30 |
Genentech, Inc. |
Methods of treating liver conditions using Notch2 antagonists
|
KR102102862B1
(ko)
|
2011-10-14 |
2020-04-22 |
제넨테크, 인크. |
항-HtrA1 항체 및 사용 방법
|
KR20140084164A
(ko)
|
2011-10-15 |
2014-07-04 |
제넨테크, 인크. |
암의 치료를 위한 scd1 길항제
|
WO2013059531A1
(en)
|
2011-10-20 |
2013-04-25 |
Genentech, Inc. |
Anti-gcgr antibodies and uses thereof
|
MX354988B
(es)
|
2011-10-25 |
2018-03-28 |
Prothena Biosciences Ltd |
Formulaciones de anticuerpo y metodos.
|
AU2012328980A1
(en)
|
2011-10-28 |
2014-04-24 |
Genentech, Inc. |
Therapeutic combinations and methods of treating melanoma
|
US9624310B2
(en)
|
2011-11-17 |
2017-04-18 |
Gundram Jung |
Methods of using bi-specific antibodies for treating B-cell-mediated autoimmune diseases or auto-reactive B-cells
|
BR112014012005A2
(pt)
|
2011-11-21 |
2017-12-19 |
Genentech Inc |
composições, métodos, formulação farmacêutica e artigo
|
US20130302274A1
(en)
|
2011-11-25 |
2013-11-14 |
Roche Glycart Ag |
Combination therapy
|
EP2788024A1
(en)
|
2011-12-06 |
2014-10-15 |
F.Hoffmann-La Roche Ag |
Antibody formulation
|
WO2013101509A2
(en)
|
2011-12-15 |
2013-07-04 |
Alternative Innovative Technologies Llc |
Hsp70 fusion protein conjugates and uses thereof
|
KR20140102759A
(ko)
|
2011-12-16 |
2014-08-22 |
모더나 세라퓨틱스, 인코포레이티드 |
변형된 뉴클레오사이드, 뉴클레오타이드 및 핵산 조성물
|
PL2794651T3
(pl)
|
2011-12-22 |
2022-12-27 |
F.Hoffmann-La Roche Ag |
Kombinacje elementów wektora ekspresyjnego, nowe sposoby generowania komórek produkcyjnych i ich zastosowanie do rekombinowanej produkcji polipeptydów
|
TR201815709T4
(tr)
|
2011-12-22 |
2018-11-21 |
Hoffmann La Roche |
İyon değişim membranı kromatografisi.
|
KR102280111B1
(ko)
|
2011-12-22 |
2021-07-21 |
에프. 호프만-라 로슈 아게 |
발현 벡터 구성, 신규한 생산 세포 생성 방법 및 폴리펩티드의 재조합 생산을 위한 그의 용도
|
KR20140107295A
(ko)
|
2011-12-22 |
2014-09-04 |
에프. 호프만-라 로슈 아게 |
진핵 세포용 전장 항체 표시 시스템 및 그것의 용도
|
AR089434A1
(es)
|
2011-12-23 |
2014-08-20 |
Genentech Inc |
Procedimiento para preparar formulaciones con alta concentracion de proteinas
|
TW201333035A
(zh)
|
2011-12-30 |
2013-08-16 |
Abbvie Inc |
針對il-13及/或il-17之雙特異性結合蛋白
|
PT3130347T
(pt)
|
2011-12-30 |
2019-12-10 |
Halozyme Inc |
Variantes de polipéptidos de ph20, suas formulações e utilizações
|
WO2013101771A2
(en)
|
2011-12-30 |
2013-07-04 |
Genentech, Inc. |
Compositions and method for treating autoimmune diseases
|
WO2013106489A1
(en)
|
2012-01-09 |
2013-07-18 |
The Scripps Research Institute |
Humanized antibodies with ultralong cdr3s
|
WO2013106485A2
(en)
|
2012-01-09 |
2013-07-18 |
The Scripps Research Institute |
Ultralong complementarity determining regions and uses thereof
|
CN104168920A
(zh)
|
2012-01-18 |
2014-11-26 |
霍夫曼-拉罗奇有限公司 |
使用fgf19调控剂的方法
|
JP6242813B2
(ja)
|
2012-01-18 |
2017-12-06 |
ジェネンテック, インコーポレイテッド |
抗lrp5抗体及び使用方法
|
WO2013109279A2
(en)
*
|
2012-01-19 |
2013-07-25 |
Therapeutic Proteins Inc. |
Stabilization of the anti-cd20 antibody rituximab
|
WO2013116287A1
(en)
|
2012-01-31 |
2013-08-08 |
Genentech, Inc. |
Anti-ig-e m1' antibodies and methods using same
|
BR112014019741A2
(pt)
|
2012-02-11 |
2020-12-22 |
Genentech, Inc |
Usos de um antagonista da via wnt, uso de uma terapia anticâncer, método de identificação de um indivíduo com câncer, métodos para prever, método de inibição da proliferação de uma célula de câncer, uso de um antagonista da translocação de r-spondina e antagonista da translocação de r-spondina isolado
|
JP6152120B2
(ja)
|
2012-02-15 |
2017-06-21 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Fc受容体に基づくアフィニティークロマトグラフィー
|
CN109880867A
(zh)
|
2012-03-27 |
2019-06-14 |
弗·哈夫曼-拉罗切有限公司 |
用于重组蛋白质的改进的收获操作
|
JP2015514710A
(ja)
|
2012-03-27 |
2015-05-21 |
ジェネンテック, インコーポレイテッド |
Her3阻害剤に関する診断及び治療
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
CA2868398A1
(en)
|
2012-04-02 |
2013-10-10 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of cosmetic proteins and peptides
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
US9878056B2
(en)
|
2012-04-02 |
2018-01-30 |
Modernatx, Inc. |
Modified polynucleotides for the production of cosmetic proteins and peptides
|
MX356800B
(es)
|
2012-04-05 |
2018-06-13 |
Ac Immune Sa |
Anticuerpo tau humanizado.
|
US10130714B2
(en)
|
2012-04-14 |
2018-11-20 |
Academia Sinica |
Enhanced anti-influenza agents conjugated with anti-inflammatory activity
|
RU2014148162A
(ru)
|
2012-05-01 |
2016-06-20 |
Дженентек, Инк. |
Анти-pmel17 антитела и их иммуноконъюгаты
|
WO2013170191A1
(en)
|
2012-05-11 |
2013-11-14 |
Genentech, Inc. |
Methods of using antagonists of nad biosynthesis from nicotinamide
|
WO2013177470A1
(en)
|
2012-05-23 |
2013-11-28 |
Genentech, Inc. |
Selection method for therapeutic agents
|
CN104364266A
(zh)
|
2012-06-15 |
2015-02-18 |
霍夫曼-拉罗奇有限公司 |
抗-pcsk9抗体,制剂,剂量给药,和使用方法
|
ES2604012T3
(es)
|
2012-07-04 |
2017-03-02 |
F. Hoffmann-La Roche Ag |
Conjugados de antígeno-anticuerpo unidos covalentemente
|
MX353951B
(es)
|
2012-07-04 |
2018-02-07 |
Hoffmann La Roche |
Anticuerpos de anti-teofilina y metodos de uso.
|
CA2872192A1
(en)
|
2012-07-04 |
2014-01-09 |
F. Hoffmann-La Roche Ag |
Anti-biotin antibodies and methods of use
|
EP2870157B1
(en)
|
2012-07-04 |
2017-08-30 |
Rhizen Pharmaceuticals S.A. |
Selective pi3k delta inhibitors
|
CN110042114A
(zh)
|
2012-07-05 |
2019-07-23 |
弗·哈夫曼-拉罗切有限公司 |
表达和分泌***
|
SG11201500096YA
(en)
|
2012-07-09 |
2015-02-27 |
Genentech Inc |
Immunoconjugates comprising anti - cd79b antibodies
|
SG11201500087VA
(en)
|
2012-07-09 |
2015-02-27 |
Genentech Inc |
Immunoconjugates comprising anti-cd22 antibodies
|
TW201408698A
(zh)
|
2012-07-09 |
2014-03-01 |
Genentech Inc |
抗cd79b抗體及免疫結合物
|
CA2874904A1
(en)
|
2012-07-09 |
2014-01-16 |
Genentech, Inc. |
Immunoconjugates comprising anti-cd22 antibodies
|
WO2014011955A2
(en)
|
2012-07-12 |
2014-01-16 |
Abbvie, Inc. |
Il-1 binding proteins
|
HUE056217T2
(hu)
|
2012-07-13 |
2022-02-28 |
Roche Glycart Ag |
Bispecifikus anti-VEGF/anti-ANG-2 antitestek és ezek alkalmazása szemészeti érbetegségek kezelésében
|
BR112015002263A2
(pt)
|
2012-08-02 |
2017-12-12 |
Hoffmann La Roche |
polipeptídeo de fusão, polipeptídeo de fusão dimérico, método para a produção de um receptor fc solúvel, uso de um polipeptídeo de fusão imobilizado e composição farmacêutica
|
SG10201800535XA
(en)
|
2012-08-07 |
2018-02-27 |
Roche Glycart Ag |
Composition comprising two antibodies engineered to have reduced and increased effector function
|
AU2013306098A1
(en)
|
2012-08-18 |
2015-02-12 |
Academia Sinica |
Cell-permeable probes for identification and imaging of sialidases
|
WO2014031762A1
(en)
|
2012-08-21 |
2014-02-27 |
Academia Sinica |
Benzocyclooctyne compounds and uses thereof
|
US9777067B2
(en)
|
2012-09-27 |
2017-10-03 |
Massachusetts Institute Of Technology |
HER2- and VEGF-A-binding proteins with enhanced stability
|
CA2890263C
(en)
|
2012-11-01 |
2020-03-10 |
Abbvie Inc. |
Anti-vegf/dll4 dual variable domain immunoglobulins and uses thereof
|
EP2914343B1
(en)
|
2012-11-02 |
2019-03-06 |
TG Therapeutics, Inc. |
Combination of anti-cd20 antibody and pi3 kinase selective inhibitor
|
CA2890207A1
(en)
|
2012-11-05 |
2014-05-08 |
Foundation Medicine, Inc. |
Novel ntrk1 fusion molecules and uses thereof
|
CA2884431A1
(en)
|
2012-11-08 |
2014-05-15 |
F. Hoffmann-La Roche Ag |
Her3 antigen binding proteins binding to the beta-hairpin of her3
|
WO2014078268A2
(en)
|
2012-11-13 |
2014-05-22 |
Genentech, Inc. |
Anti-hemagglutinin antibodies and methods of use
|
JP6475631B2
(ja)
|
2012-11-19 |
2019-02-27 |
バリオファルム・アクチェンゲゼルシャフト |
Cd20およびcd95に結合する組換え二重特異性抗体
|
JP6144355B2
(ja)
|
2012-11-26 |
2017-06-07 |
モデルナティエックス インコーポレイテッドModernaTX,Inc. |
化学修飾mRNA
|
CN104994885B
(zh)
|
2012-12-19 |
2017-09-29 |
基因泰克公司 |
用于放射性卤素蛋白质标记的方法和组合物
|
JP6475167B2
(ja)
|
2012-12-21 |
2019-02-27 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
ジスルフィド結合した多価mhcクラスiを含む多機能タンパク質
|
CA3150658A1
(en)
|
2013-01-18 |
2014-07-24 |
Foundation Medicine, Inc. |
Methods of treating cholangiocarcinoma
|
WO2014116749A1
(en)
|
2013-01-23 |
2014-07-31 |
Genentech, Inc. |
Anti-hcv antibodies and methods of using thereof
|
WO2014120555A1
(en)
|
2013-01-31 |
2014-08-07 |
The Regents Of The University Of California |
Antibodies specific for urokinase-type plasminogen activator and methods of use thereof
|
JP2016509045A
(ja)
|
2013-02-22 |
2016-03-24 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
がんを治療し、薬剤耐性を防止する方法
|
CA2896259A1
(en)
|
2013-02-26 |
2014-09-04 |
Roche Glycart Ag |
Anti-mcsp antibodies
|
US9925240B2
(en)
|
2013-03-06 |
2018-03-27 |
Genentech, Inc. |
Methods of treating and preventing cancer drug resistance
|
CN111363047A
(zh)
*
|
2013-03-12 |
2020-07-03 |
分子模板公司 |
用于引起细胞内化的cd20结合免疫毒素及其使用方法
|
BR112015022210A8
(pt)
|
2013-03-13 |
2018-01-23 |
Genentech Inc |
formulações de anticorpo
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
EP2968540A2
(en)
|
2013-03-14 |
2016-01-20 |
Genentech, Inc. |
Combinations of a mek inhibitor compound with an her3/egfr inhibitor compound and methods of use
|
WO2014159835A1
(en)
|
2013-03-14 |
2014-10-02 |
Genentech, Inc. |
Anti-b7-h4 antibodies and immunoconjugates
|
CA2905070A1
(en)
|
2013-03-14 |
2014-09-25 |
Genentech, Inc. |
Methods of treating cancer and preventing cancer drug resistance
|
EP2972373B1
(en)
|
2013-03-15 |
2019-10-09 |
F.Hoffmann-La Roche Ag |
Biomarkers and methods of treating pd-1 and pd-l1 related conditions
|
MX2015012872A
(es)
|
2013-03-15 |
2016-02-03 |
Ac Immune Sa |
Anticuerpos anti-tau y metodos de uso.
|
WO2014145098A1
(en)
|
2013-03-15 |
2014-09-18 |
Genentech, Inc. |
Cell culture compositions with antioxidants and methods for polypeptide production
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
JP6527132B2
(ja)
|
2013-03-15 |
2019-06-05 |
ジェネンテック, インコーポレイテッド |
肝臓がんの診断及び治療のための組成物及び方法
|
BR112015021521A2
(pt)
|
2013-03-15 |
2017-10-10 |
Genentech Inc |
anticorpos anti-crth2 e métodos para seu uso
|
WO2014144280A2
(en)
|
2013-03-15 |
2014-09-18 |
Abbvie Inc. |
DUAL SPECIFIC BINDING PROTEINS DIRECTED AGAINST IL-1β AND / OR IL-17
|
TR201809571T4
(tr)
|
2013-03-15 |
2018-07-23 |
Hoffmann La Roche |
Ll-22 polipeptidleri ile ıl-22 fc füzyon proteinleri ve kullanım yöntemleri.
|
MX2015011899A
(es)
|
2013-03-15 |
2016-05-05 |
Genentech Inc |
Metodos para el tratamiento de cáncer y prevención de resistencia a los fármacos para el cáncer.
|
UA118028C2
(uk)
|
2013-04-03 |
2018-11-12 |
Рош Глікарт Аг |
Біспецифічне антитіло, специфічне щодо fap і dr5, антитіло, специфічне щодо dr5, і спосіб їх застосування
|
RU2687043C2
(ru)
|
2013-04-29 |
2019-05-06 |
Ф. Хоффманн-Ля Рош Аг |
МОДИФИЦИРОВАННЫЕ АСИММЕТРИЧНЫЕ АНТИТЕЛА, СВЯЗЫВАЮЩИЕ Fc-РЕЦЕПТОР, И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
|
CN105164158A
(zh)
|
2013-04-29 |
2015-12-16 |
豪夫迈·罗氏有限公司 |
消除对FcRn-结合的抗-IGF-1R抗体及其在血管性眼病治疗中的用途
|
EP2992012B1
(en)
|
2013-04-29 |
2019-07-17 |
F.Hoffmann-La Roche Ag |
Human fcrn-binding modified antibodies and methods of use
|
EP2999716A2
(en)
|
2013-05-20 |
2016-03-30 |
F. Hoffmann-La Roche AG |
Anti-transferrin receptor antibodies and methods of use
|
MX369022B
(es)
|
2013-05-31 |
2019-10-25 |
Genentech Inc |
Anticuerpos anti-ácido teicoico de la pared celular y conjugados.
|
RU2687044C2
(ru)
|
2013-05-31 |
2019-05-06 |
Дженентек, Инк. |
Антитела против стеночной тейхоевой кислоты и их конъюгаты
|
US10086054B2
(en)
|
2013-06-26 |
2018-10-02 |
Academia Sinica |
RM2 antigens and use thereof
|
EP3013347B1
(en)
|
2013-06-27 |
2019-12-11 |
Academia Sinica |
Glycan conjugates and use thereof
|
TW201534726A
(zh)
|
2013-07-03 |
2015-09-16 |
Halozyme Inc |
熱穩定ph20玻尿酸酶變異體及其用途
|
CN105814074B
(zh)
|
2013-07-18 |
2020-04-21 |
图鲁斯生物科学有限责任公司 |
具有超长互补决定区的人源化抗体
|
EP3022224A2
(en)
|
2013-07-18 |
2016-05-25 |
Fabrus, Inc. |
Antibodies with ultralong complementarity determining regions
|
EP4036118A1
(en)
|
2013-08-01 |
2022-08-03 |
Five Prime Therapeutics, Inc. |
Afucosylated anti-fgfr2iiib antibodies
|
US10093978B2
(en)
|
2013-08-12 |
2018-10-09 |
Genentech, Inc. |
Compositions for detecting complement factor H (CFH) and complement factor I (CFI) polymorphisms
|
CN105682666B
(zh)
|
2013-09-06 |
2021-06-01 |
中央研究院 |
使用醣脂激活人类iNKT细胞
|
CN105518027A
(zh)
|
2013-09-17 |
2016-04-20 |
豪夫迈·罗氏有限公司 |
使用抗lgr5抗体的方法
|
CN103524621B
(zh)
*
|
2013-09-27 |
2015-04-01 |
北京济福霖生物技术有限公司 |
一种抗人cd20嵌合单克隆抗体
|
EP3052106A4
(en)
|
2013-09-30 |
2017-07-19 |
ModernaTX, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
JP2016538829A
(ja)
|
2013-10-03 |
2016-12-15 |
モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. |
低密度リポタンパク質受容体をコードするポリヌクレオチド
|
MX2016003593A
(es)
|
2013-10-11 |
2016-06-02 |
Hoffmann La Roche |
Anticuerpos de cadena ligera variable comun intercambiada de dominio multiespecifico.
|
KR20160068855A
(ko)
|
2013-10-11 |
2016-06-15 |
제넨테크, 인크. |
Nsp4 억제제 및 사용 방법
|
MX2016003744A
(es)
|
2013-10-11 |
2016-08-11 |
Us Health |
Anticuerpos tem8 y su uso.
|
MX2016004802A
(es)
|
2013-10-18 |
2016-07-18 |
Genentech Inc |
Anticuerpos anti-r-espondina (anti-rspo) y metodos de uso.
|
RU2016119425A
(ru)
|
2013-10-23 |
2017-11-28 |
Дженентек, Инк. |
Способы диагностики и лечения эозинофильных заболеваний
|
CN104623637A
(zh)
|
2013-11-07 |
2015-05-20 |
健能隆医药技术(上海)有限公司 |
Il-22二聚体在制备静脉注射药物中的应用
|
AU2014351996B2
(en)
|
2013-11-21 |
2020-01-02 |
F. Hoffmann-La Roche Ag |
Anti-alpha-synuclein antibodies and methods of use
|
CN113861293A
(zh)
|
2013-12-09 |
2021-12-31 |
爱乐科斯公司 |
抗Siglec-8抗体及其使用方法
|
MA39095A1
(fr)
|
2013-12-13 |
2018-08-31 |
Genentech Inc |
Anticorps et immunoconjugués anti-cd33
|
EP3083692B1
(en)
|
2013-12-17 |
2020-02-19 |
F.Hoffmann-La Roche Ag |
Methods of treating her2-positive cancers using pd-1 axis binding antagonists and anti-her2 antibodies
|
WO2015095410A1
(en)
|
2013-12-17 |
2015-06-25 |
Genentech, Inc. |
Methods of treating cancer using pd-1 axis binding antagonists and an anti-cd20 antibody
|
DK3083689T3
(da)
|
2013-12-17 |
2020-08-03 |
Genentech Inc |
Anti-CD3-antistoffer og fremgangsmåder til anvendelse
|
CA2934028A1
(en)
|
2013-12-17 |
2015-06-25 |
Genentech, Inc. |
Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists
|
PL3083680T3
(pl)
|
2013-12-20 |
2020-06-29 |
F. Hoffmann-La Roche Ag |
Humanizowane przeciwciała przeciwko białku tau(pS422) i sposoby stosowania
|
TWI728373B
(zh)
|
2013-12-23 |
2021-05-21 |
美商建南德克公司 |
抗體及使用方法
|
EP3089996B1
(en)
|
2014-01-03 |
2021-07-28 |
F. Hoffmann-La Roche AG |
Bispecific anti-hapten/anti-blood brain barrier receptor antibodies, complexes thereof and their use as blood brain barrier shuttles
|
BR112016012666A2
(pt)
|
2014-01-03 |
2017-09-26 |
Hoffmann La Roche |
conjugado, anticorpos, formulação farmacêutica e usos de conjugado
|
WO2015103549A1
(en)
|
2014-01-03 |
2015-07-09 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
JP6521464B2
(ja)
|
2014-01-03 |
2019-05-29 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
共有結合で連結されたポリペプチド毒素−抗体コンジュゲート
|
EP3092251B1
(en)
|
2014-01-06 |
2021-01-20 |
F. Hoffmann-La Roche AG |
Monovalent blood brain barrier shuttle modules
|
WO2015107026A1
(en)
|
2014-01-15 |
2015-07-23 |
F. Hoffmann-La Roche Ag |
Fc-region variants with modified fcrn- and maintained protein a-binding properties
|
US10150818B2
(en)
|
2014-01-16 |
2018-12-11 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
US9982041B2
(en)
|
2014-01-16 |
2018-05-29 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
WO2015112909A1
(en)
|
2014-01-24 |
2015-07-30 |
Genentech, Inc. |
Methods of using anti-steap1 antibodies and immunoconjugates
|
EP3099704B1
(en)
|
2014-01-27 |
2021-03-17 |
Molecular Templates, Inc. |
Mhc class i epitope delivering polypeptides
|
WO2015120075A2
(en)
|
2014-02-04 |
2015-08-13 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
EP3718563A1
(en)
|
2014-02-08 |
2020-10-07 |
F. Hoffmann-La Roche AG |
Methods of treating alzheimer's disease
|
TW202239429A
(zh)
|
2014-02-08 |
2022-10-16 |
美商建南德克公司 |
治療阿茲海默症之方法
|
AU2015217271B2
(en)
|
2014-02-12 |
2018-10-25 |
Genentech, Inc. |
Anti-Jagged1 antibodies and methods of use
|
BR112016018980A2
(pt)
|
2014-02-21 |
2017-10-10 |
Genentech Inc |
método de tratamento de um distúrbio, anticorpo multiespecífico, ácido nucleico isolado, célula hospedeira, métodos de produzir um anticorpo, de produção de uma metade de anticorpo ou de um anticorpo multiespecífico e de produção de um anticorpo multiespecífico, imunoconjugado e formulação farmacêutica
|
TWI558399B
(zh)
|
2014-02-26 |
2016-11-21 |
美國禮來大藥廠 |
癌症之組合療法
|
JP6825909B2
(ja)
|
2014-02-28 |
2021-02-03 |
アラコス インコーポレイテッド |
シグレック−8関連疾患を処置するための方法および組成物
|
TW201622744A
(zh)
|
2014-03-04 |
2016-07-01 |
美國禮來大藥廠 |
癌症之組合療法
|
US11142584B2
(en)
|
2014-03-11 |
2021-10-12 |
Molecular Templates, Inc. |
CD20-binding proteins comprising Shiga toxin A subunit effector regions for inducing cellular internalization and methods using same
|
MA39746A
(fr)
|
2014-03-14 |
2021-04-28 |
Hoffmann La Roche |
Compositions de sécrétion de polypeptides hétérologues et procédés associés
|
WO2015140591A1
(en)
|
2014-03-21 |
2015-09-24 |
Nordlandssykehuset Hf |
Anti-cd14 antibodies and uses thereof
|
BR112016021383A2
(pt)
|
2014-03-24 |
2017-10-03 |
Genentech Inc |
Método para identificar um paciente com câncer que é susceptível ou menos susceptível a responder ao tratamento com um antagonista de cmet, método para identificar um paciente apresentando câncer previamente tratado, método para determinar a expressão do biomarcador hgf, antagonista anti-c-met e seu uso, kit de diagnóstico e seu método de preparo
|
TWI687428B
(zh)
|
2014-03-27 |
2020-03-11 |
中央研究院 |
反應性標記化合物及其用途
|
EP3632934A1
(en)
|
2014-03-31 |
2020-04-08 |
F. Hoffmann-La Roche AG |
Anti-ox40 antibodies and methods of use
|
WO2015153514A1
(en)
|
2014-03-31 |
2015-10-08 |
Genentech, Inc. |
Combination therapy comprising anti-angiogenesis agents and ox40 binding agonists
|
WO2015164615A1
(en)
|
2014-04-24 |
2015-10-29 |
University Of Oslo |
Anti-gluten antibodies and uses thereof
|
MX2016015162A
(es)
|
2014-05-22 |
2017-03-03 |
Genentech Inc |
Anticuerpos anti - gpc3 e inmunoconjugados.
|
CN106661622B
(zh)
|
2014-05-23 |
2020-08-21 |
豪夫迈·罗氏有限公司 |
Mit生物标志物和使用它们的方法
|
EP3149161B1
(en)
|
2014-05-27 |
2021-07-28 |
Academia Sinica |
Fucosidase from bacteroides and methods using the same
|
CN106573971A
(zh)
|
2014-05-27 |
2017-04-19 |
中央研究院 |
抗cd20醣抗体及其用途
|
US10118969B2
(en)
|
2014-05-27 |
2018-11-06 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
HUE054916T2
(hu)
|
2014-05-27 |
2021-10-28 |
Rhizen Pharmaceuticals S A |
PI3K delta szelektív gátló kristályos toszilát-sója gyógyszerkészítményekben történõ alkalmazásra
|
AU2015267045B2
(en)
|
2014-05-27 |
2021-02-25 |
Academia Sinica |
Anti-HER2 glycoantibodies and uses thereof
|
TWI732738B
(zh)
|
2014-05-28 |
2021-07-11 |
中央研究院 |
抗TNF-α醣抗體及其用途
|
MX2016016288A
(es)
|
2014-06-11 |
2017-10-12 |
Molecular Templates Inc |
Polipeptidos efectores de la subunidad a de la toxina shiga resistentes a la disociacion por proteasa y moleculas dirigidas a las celulas que los comprenden.
|
JP2017526618A
(ja)
|
2014-06-11 |
2017-09-14 |
ジェネンテック, インコーポレイテッド |
抗LgR5抗体及びその使用
|
JP2017517552A
(ja)
|
2014-06-13 |
2017-06-29 |
ジェネンテック, インコーポレイテッド |
抗癌剤耐性の治療及び防止方法
|
AR100978A1
(es)
|
2014-06-26 |
2016-11-16 |
Hoffmann La Roche |
LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS
|
KR20170026362A
(ko)
|
2014-06-26 |
2017-03-08 |
에프. 호프만-라 로슈 아게 |
항-brdu 항체 및 사용 방법
|
EP3166974A1
(en)
|
2014-07-11 |
2017-05-17 |
Genentech, Inc. |
Anti-pd-l1 antibodies and diagnostic uses thereof
|
EP3166627A1
(en)
|
2014-07-11 |
2017-05-17 |
Genentech, Inc. |
Notch pathway inhibition
|
WO2016019969A1
(en)
|
2014-08-08 |
2016-02-11 |
Ludwig-Maximilians-Universität München |
Subcutaneously administered bispecific antibodies for use in the treatment of cancer
|
TWI751102B
(zh)
|
2014-08-28 |
2022-01-01 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
AU2015308818B2
(en)
|
2014-08-28 |
2021-02-25 |
Bioatla Llc |
Conditionally active chimeric antigen receptors for modified T-cells
|
US20170246272A1
(en)
|
2014-09-05 |
2017-08-31 |
Opexa Therapeutics, Inc. |
Compositions and methods for treating b cell mediated autoimmune disorders
|
WO2016040369A2
(en)
|
2014-09-08 |
2016-03-17 |
Academia Sinica |
HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS
|
CA2957354A1
(en)
|
2014-09-12 |
2016-03-17 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
US9751946B2
(en)
|
2014-09-12 |
2017-09-05 |
Genentech, Inc. |
Anti-CLL-1 antibodies and immunoconjugates
|
EP3191518B1
(en)
|
2014-09-12 |
2020-01-15 |
Genentech, Inc. |
Anti-b7-h4 antibodies and immunoconjugates
|
EA201790545A1
(ru)
|
2014-09-12 |
2017-07-31 |
Дженентек, Инк. |
Антитела и иммуноконъюгаты против her2
|
BR112017004393A2
(pt)
|
2014-09-15 |
2018-02-27 |
Genentech Inc |
formulações de anticorpo
|
JP6730261B2
(ja)
|
2014-09-17 |
2020-07-29 |
ジェネンテック, インコーポレイテッド |
抗her2抗体を含む免疫複合体
|
PL3262071T3
(pl)
|
2014-09-23 |
2020-08-10 |
F. Hoffmann-La Roche Ag |
Sposób stosowania immunokoniugatów anty-CD79b
|
WO2016061389A2
(en)
|
2014-10-16 |
2016-04-21 |
Genentech, Inc. |
Anti-alpha-synuclein antibodies and methods of use
|
EP3223865A4
(en)
|
2014-10-31 |
2018-10-03 |
Jounce Therapeutics, Inc. |
Methods of treating conditions with antibodies that bind b7-h4
|
CN114381521A
(zh)
|
2014-11-03 |
2022-04-22 |
豪夫迈·罗氏有限公司 |
用于ox40激动剂治疗的功效预测和评估的方法和生物标志物
|
CA2966523A1
(en)
|
2014-11-03 |
2016-05-12 |
Genentech, Inc. |
Assays for detecting t cell immune subsets and methods of use thereof
|
CA2961439A1
(en)
|
2014-11-05 |
2016-05-12 |
Genentech, Inc. |
Anti-fgfr2/3 antibodies and methods using same
|
RU2020141422A
(ru)
|
2014-11-05 |
2021-01-13 |
Дженентек, Инк. |
Способы получения двуцепочечных белков в бактериях
|
CA2966558C
(en)
|
2014-11-05 |
2024-03-12 |
Genentech, Inc. |
Methods of producing two chain proteins in bacteria
|
AR102522A1
(es)
|
2014-11-06 |
2017-03-08 |
Hoffmann La Roche |
Variantes de región fc con propiedades modificadas de unión a fcrn y proteína a
|
CA2960797A1
(en)
|
2014-11-06 |
2016-05-12 |
F. Hoffmann-La Roche Ag |
Fc-region variants with modified fcrn-binding and methods of use
|
WO2016073157A1
(en)
|
2014-11-06 |
2016-05-12 |
Genentech, Inc. |
Anti-ang2 antibodies and methods of use thereof
|
RU2017119428A
(ru)
|
2014-11-06 |
2018-12-06 |
Дженентек, Инк. |
Комбинированная терапия, включающая применение агонистов, связывающихся с ох40, и ингибиторов tigit
|
CR20170240A
(es)
|
2014-11-10 |
2018-04-03 |
Genentech Inc |
Anticuerpos anti-interleucina-33 y sus usos
|
EP3552488A1
(en)
|
2014-11-10 |
2019-10-16 |
F. Hoffmann-La Roche AG |
Animal model for nephropathy and agents for treating the same
|
EP3218397B8
(en)
|
2014-11-14 |
2021-04-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to ebola virus glycoprotein and their use
|
WO2016081384A1
(en)
|
2014-11-17 |
2016-05-26 |
Genentech, Inc. |
Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists
|
US11008403B2
(en)
|
2014-11-19 |
2021-05-18 |
Genentech, Inc. |
Anti-transferrin receptor / anti-BACE1 multispecific antibodies and methods of use
|
WO2016081639A1
(en)
|
2014-11-19 |
2016-05-26 |
Genentech, Inc. |
Antibodies against bace1 and use thereof for neural disease immunotherapy
|
US10508151B2
(en)
|
2014-11-19 |
2019-12-17 |
Genentech, Inc. |
Anti-transferrin receptor antibodies and methods of use
|
BR112017010324A2
(pt)
|
2014-11-20 |
2018-05-15 |
F. Hoffmann-La Roche Ag |
método para tratar ou retardar a progressão de um câncer em um indivíduo, moléculas, métodos para aumentar a função imune em um indivíduo e para selecionar um paciente para tratamento, kits, composição farmacêutica e usos de uma combinação de uma molécula
|
JP6751393B2
(ja)
|
2014-12-03 |
2020-09-02 |
ジェネンテック, インコーポレイテッド |
抗staphylococcus aureus抗体リファマイシン抱合体及びその使用
|
KR20170086536A
(ko)
|
2014-12-03 |
2017-07-26 |
제넨테크, 인크. |
항-스타필로코커스 아우레우스 항체 리파마이신 접합체 및 이의 용도
|
EP3227332B1
(en)
|
2014-12-03 |
2019-11-06 |
F.Hoffmann-La Roche Ag |
Multispecific antibodies
|
US9975949B2
(en)
|
2014-12-05 |
2018-05-22 |
Genentech, Inc. |
Anti-CD79b antibodies and methods of use
|
RU2017120039A
(ru)
|
2014-12-10 |
2019-01-10 |
Дженентек, Инк. |
Антитела к рецепторам гематоэнцефалического барьера и способы их применения
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
RU2746356C2
(ru)
|
2014-12-19 |
2021-04-12 |
Чугаи Сейяку Кабусики Кайся |
Антитела к с5 и способы их применения
|
PT3233912T
(pt)
|
2014-12-19 |
2021-08-09 |
Regenesance B V |
Antocorpos que se ligam a c6 humano e utilizações destes
|
WO2016111947A2
(en)
|
2015-01-05 |
2016-07-14 |
Jounce Therapeutics, Inc. |
Antibodies that inhibit tim-3:lilrb2 interactions and uses thereof
|
US10495645B2
(en)
|
2015-01-16 |
2019-12-03 |
Academia Sinica |
Cancer markers and methods of use thereof
|
US9975965B2
(en)
|
2015-01-16 |
2018-05-22 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
US20160208018A1
(en)
|
2015-01-16 |
2016-07-21 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for ror1
|
WO2016117346A1
(en)
|
2015-01-22 |
2016-07-28 |
Chugai Seiyaku Kabushiki Kaisha |
A combination of two or more anti-c5 antibodies and methods of use
|
EP3248005B1
(en)
|
2015-01-24 |
2020-12-09 |
Academia Sinica |
Novel glycan conjugates and methods of use thereof
|
MX2017009181A
(es)
*
|
2015-01-26 |
2017-11-22 |
Cellectis |
Receptores de antigenos quimericos de cadena sencilla especificos de anti-cll1 para inmunoterapia de cancer.
|
US10330683B2
(en)
|
2015-02-04 |
2019-06-25 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
JP6444486B2
(ja)
|
2015-02-05 |
2018-12-26 |
モレキュラー テンプレーツ, インク.Molecular Templates, Inc. |
志賀毒素aサブユニットエフェクター領域を含む多価cd20結合分子及びそれらの強化組成物
|
KR20170110129A
(ko)
|
2015-02-05 |
2017-10-10 |
추가이 세이야쿠 가부시키가이샤 |
이온 농도 의존적 항원 결합 도메인을 포함하는 항체, Fc 영역 개변체, IL-8에 결합하는 항체, 및 그들의 사용
|
US10301377B2
(en)
|
2015-02-24 |
2019-05-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Middle east respiratory syndrome coronavirus immunogens, antibodies, and their use
|
MX2017011486A
(es)
|
2015-03-16 |
2018-06-15 |
Genentech Inc |
Métodos de detección y cuantificación de il-13 y sus usos en el diagnóstico y tratamiento de enfermedades asociadas a th2.
|
WO2016146833A1
(en)
|
2015-03-19 |
2016-09-22 |
F. Hoffmann-La Roche Ag |
Biomarkers for nad(+)-diphthamide adp ribosyltransferase resistance
|
HUE049081T2
(hu)
|
2015-03-20 |
2020-09-28 |
The United States Of America As |
GP120 elleni neutralizáló antitestek és alkalmazásuk
|
SI3273992T1
(sl)
|
2015-03-23 |
2020-09-30 |
Jounce Therapeutics, Inc. |
Protitelesa proti ICOS
|
LT3274370T
(lt)
|
2015-03-23 |
2020-02-10 |
Bayer Pharma Aktiengesellschaft |
Antikūnai prieš ceacam6 ir jų panaudojimas
|
US10472412B2
(en)
|
2015-03-25 |
2019-11-12 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Bispecific multivalent fusion proteins
|
JP6903587B2
(ja)
|
2015-04-03 |
2021-07-14 |
ユーリカ セラピューティックス, インコーポレイテッド |
Afpペプチド/mhc複合体を標的化する構築物およびその使用
|
CN107709364A
(zh)
|
2015-04-07 |
2018-02-16 |
豪夫迈·罗氏有限公司 |
具有激动剂活性的抗原结合复合体及使用方法
|
CN107969128A
(zh)
|
2015-04-17 |
2018-04-27 |
高山免疫科学股份有限公司 |
具有可调的亲和力的免疫调节蛋白
|
JP7044553B2
(ja)
|
2015-04-24 |
2022-03-30 |
ジェネンテック, インコーポレイテッド |
結合ポリペプチドを含む細菌を特定する方法
|
JP2018520642A
(ja)
|
2015-05-01 |
2018-08-02 |
ジェネンテック, インコーポレイテッド |
マスク抗cd3抗体及びその使用方法
|
WO2016179194A1
(en)
|
2015-05-04 |
2016-11-10 |
Jounce Therapeutics, Inc. |
Lilra3 and method of using the same
|
EP4238994A3
(en)
|
2015-05-11 |
2024-02-07 |
F. Hoffmann-La Roche AG |
Compositions and methods of treating lupus nephritis
|
ES2835866T3
(es)
|
2015-05-12 |
2021-06-23 |
Hoffmann La Roche |
Procedimientos terapéuticos y de diagnóstico para el cáncer
|
KR20180012753A
(ko)
|
2015-05-29 |
2018-02-06 |
제넨테크, 인크. |
암에 대한 치료 및 진단 방법
|
WO2016196381A1
(en)
|
2015-05-29 |
2016-12-08 |
Genentech, Inc. |
Pd-l1 promoter methylation in cancer
|
EP3302563A1
(en)
|
2015-05-29 |
2018-04-11 |
H. Hoffnabb-La Roche Ag |
Humanized anti-ebola virus glycoprotein antibodies and methods of use
|
CN107849096B
(zh)
|
2015-05-30 |
2022-05-24 |
分子模板公司 |
去免疫化的志贺毒素a亚基支架和包含它们的细胞靶向分子
|
CN107810012A
(zh)
|
2015-06-02 |
2018-03-16 |
豪夫迈·罗氏有限公司 |
使用抗il‑34抗体治疗神经疾病的组合物和方法
|
WO2016196975A1
(en)
|
2015-06-03 |
2016-12-08 |
The United States Of America, As Represented By The Secretary Department Of Health & Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
CN107849124B
(zh)
|
2015-06-05 |
2021-09-24 |
基因泰克公司 |
抗tau抗体及使用方法
|
EP3303399A1
(en)
|
2015-06-08 |
2018-04-11 |
H. Hoffnabb-La Roche Ag |
Methods of treating cancer using anti-ox40 antibodies
|
CA2988420A1
(en)
|
2015-06-08 |
2016-12-15 |
Genentech, Inc. |
Methods of treating cancer using anti-ox40 antibodies and pd-1 axis binding antagonists
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
JP2018524295A
(ja)
|
2015-06-15 |
2018-08-30 |
ジェネンテック, インコーポレイテッド |
抗体及び免疫複合体
|
TWI731861B
(zh)
|
2015-06-16 |
2021-07-01 |
美商建南德克公司 |
FcRH5之人源化及親和力成熟抗體及使用方法
|
WO2016204966A1
(en)
|
2015-06-16 |
2016-12-22 |
Genentech, Inc. |
Anti-cd3 antibodies and methods of use
|
CN107847568B
(zh)
|
2015-06-16 |
2022-12-20 |
豪夫迈·罗氏有限公司 |
抗cll-1抗体和使用方法
|
JP6846362B2
(ja)
|
2015-06-17 |
2021-03-24 |
アラコス インコーポレイテッド |
線維性疾患を処置するための方法および組成物
|
JP2018524312A
(ja)
|
2015-06-17 |
2018-08-30 |
ジェネンテック, インコーポレイテッド |
抗her2抗体及び使用方法
|
MX2017016353A
(es)
|
2015-06-17 |
2018-05-02 |
Genentech Inc |
Metodos para tratar canceres de mama metastasicos o localmente avanzados con antagonistas de union al eje de pd-1 y taxanos.
|
EP3313877B1
(en)
|
2015-06-24 |
2020-06-03 |
H. Hoffnabb-La Roche Ag |
Humanized anti-tau(ps422) antibodies and methods of use
|
DK3313879T3
(da)
|
2015-06-24 |
2022-03-14 |
Hoffmann La Roche |
Anti-transferrinreceptor-antistoffer med tilpasset affinitet
|
EP3108897A1
(en)
|
2015-06-24 |
2016-12-28 |
F. Hoffmann-La Roche AG |
Antibodies against human csf-1r for use in inducing lymphocytosis in lymphomas or leukemias
|
JP2018520153A
(ja)
|
2015-06-29 |
2018-07-26 |
ジェネンテック, インコーポレイテッド |
臓器移植における使用のためのii型抗cd20抗体
|
ES2898065T3
(es)
|
2015-06-29 |
2022-03-03 |
Ventana Med Syst Inc |
Materiales y procedimientos para realizar ensayos histoquímicos para proepirregulina y anfirregulina humanas
|
CN105384825B
(zh)
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
一种基于单域抗体的双特异性嵌合抗原受体及其应用
|
EP3341415B1
(en)
|
2015-08-28 |
2021-03-24 |
H. Hoffnabb-La Roche Ag |
Anti-hypusine antibodies and uses thereof
|
MX2018002226A
(es)
|
2015-08-28 |
2018-03-23 |
Amunix Operating Inc |
Ensamble de polipeptido quimerico y metodos para hacer y usar el mismo.
|
CR20180217A
(es)
|
2015-09-18 |
2018-05-03 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos que se unen a interleucina 8 (il-8) y sus usos
|
CA2999369C
(en)
|
2015-09-22 |
2023-11-07 |
Spring Bioscience Corporation |
Anti-ox40 antibodies and diagnostic uses thereof
|
WO2017053807A2
(en)
*
|
2015-09-23 |
2017-03-30 |
Genentech, Inc. |
Optimized variants of anti-vegf antibodies
|
WO2017053906A1
(en)
|
2015-09-24 |
2017-03-30 |
Abvitro Llc |
Hiv antibody compositions and methods of use
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
BR112018002570A2
(pt)
|
2015-10-02 |
2018-10-16 |
Hoffmann La Roche |
molécula de ligação ao antígeno biespecífica, anticorpo biespecífico, polinucleotídeos, anticorpo que se liga especificamente ao ox40, composição farmacêutica e método para inibir o crescimento de células tumorais em um indivíduo
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
AU2016329251B2
(en)
|
2015-10-02 |
2023-02-02 |
F. Hoffmann-La Roche Ag |
Anti-PD1 antibodies and methods of use
|
AR106189A1
(es)
|
2015-10-02 |
2017-12-20 |
Hoffmann La Roche |
ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO
|
CN114014936A
(zh)
|
2015-10-02 |
2022-02-08 |
豪夫迈·罗氏有限公司 |
双特异性抗人cd20/人转铁蛋白受体抗体及使用方法
|
EP3150636A1
(en)
|
2015-10-02 |
2017-04-05 |
F. Hoffmann-La Roche AG |
Tetravalent multispecific antibodies
|
KR102146319B1
(ko)
|
2015-10-02 |
2020-08-25 |
에프. 호프만-라 로슈 아게 |
Pd1 및 tim3에 특이적인 이중특이성 항체
|
IL293708A
(en)
|
2015-10-06 |
2022-08-01 |
Genentech Inc |
A method for treating multiple sclerosis
|
AU2016334623A1
(en)
|
2015-10-07 |
2018-02-15 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies with tetravalency for a costimulatory TNF receptor
|
CA2997809A1
(en)
|
2015-10-07 |
2017-04-13 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Il-7r-alpha specific antibodies for treating acute lymphoblastic leukemia
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
MA45326A
(fr)
|
2015-10-20 |
2018-08-29 |
Genentech Inc |
Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation
|
US10604577B2
(en)
|
2015-10-22 |
2020-03-31 |
Allakos Inc. |
Methods and compositions for treating systemic mastocytosis
|
US10968277B2
(en)
|
2015-10-22 |
2021-04-06 |
Jounce Therapeutics, Inc. |
Gene signatures for determining ICOS expression
|
EP3184547A1
(en)
|
2015-10-29 |
2017-06-28 |
F. Hoffmann-La Roche AG |
Anti-tpbg antibodies and methods of use
|
CN114891102A
(zh)
|
2015-10-29 |
2022-08-12 |
豪夫迈·罗氏有限公司 |
抗变体Fc区抗体及使用方法
|
HUE054093T2
(hu)
|
2015-10-30 |
2021-08-30 |
Hoffmann La Roche |
Anti-HtrA1 antitestek és azok alkalmazási eljárásai
|
EP3368074A2
(en)
|
2015-10-30 |
2018-09-05 |
Hoffmann-La Roche AG |
Anti-factor d antibodies and conjugates
|
WO2017079479A1
(en)
|
2015-11-03 |
2017-05-11 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human |
Neutralizing antibodies to hiv-1 gp41 and their use
|
JP6998869B2
(ja)
|
2015-11-08 |
2022-02-04 |
ジェネンテック, インコーポレイテッド |
多重特異性抗体のスクリーニング方法
|
RU2021107536A
(ru)
|
2015-11-23 |
2021-07-02 |
Файв Прайм Терапьютикс, Инк. |
Ингибиторы fgfr2 отдельно или в комбинации с иммуностимулирующими агентами в лечении рака
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
JP7325186B2
(ja)
|
2015-12-09 |
2023-08-14 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
抗薬物抗体の形成を減少させるためのii型抗cd20抗体
|
PL3390442T3
(pl)
|
2015-12-18 |
2024-03-18 |
Chugai Seiyaku Kabushiki Kaisha |
Przeciwciała anty-c5 i sposoby ich stosowania
|
EP3397287A1
(en)
|
2015-12-30 |
2018-11-07 |
Genentech, Inc. |
Formulations with reduced degradation of polysorbate
|
MX2018008347A
(es)
|
2016-01-08 |
2018-12-06 |
Hoffmann La Roche |
Metodos de tratamiento de canceres positivos para ace utilizando antagonistas de union a eje pd-1 y anticuerpos biespecificos anti-ace/anti-cd3.
|
WO2017127764A1
(en)
|
2016-01-20 |
2017-07-27 |
Genentech, Inc. |
High dose treatments for alzheimer's disease
|
CA3019952A1
(en)
|
2016-02-04 |
2017-08-10 |
Curis, Inc. |
Mutant smoothened and methods of using the same
|
CN109196121B
(zh)
|
2016-02-29 |
2022-01-04 |
基因泰克公司 |
用于癌症的治疗和诊断方法
|
WO2017148880A1
(en)
|
2016-03-01 |
2017-09-08 |
F. Hoffmann-La Roche Ag |
Obinutuzumab variants having altered cell death induction
|
TW201808978A
(zh)
|
2016-03-08 |
2018-03-16 |
中央研究院 |
N-聚醣及其陣列之模組化合成方法
|
TW202248213A
(zh)
|
2016-03-15 |
2022-12-16 |
日商中外製藥股份有限公司 |
使用pd-1軸結合拮抗劑和抗gpc3抗體治療癌症的方法
|
JP6943872B2
(ja)
|
2016-03-25 |
2021-10-06 |
ジェネンテック, インコーポレイテッド |
多重全抗体及び抗体複合体化薬物定量化アッセイ
|
EP3436610A1
(en)
|
2016-03-29 |
2019-02-06 |
Geltor, Inc. |
Expression of proteins in gram-negative bacteria wherein the ratio of periplasmic volume to cytoplasmic volume is between 0.5:1 and 10:1
|
KR101796277B1
(ko)
|
2016-04-12 |
2017-11-13 |
앱클론(주) |
안정성이 개선된 her2에 특이적으로 결합하는 항체
|
WO2017180864A1
(en)
|
2016-04-14 |
2017-10-19 |
Genentech, Inc. |
Anti-rspo3 antibodies and methods of use
|
JP2019515670A
(ja)
|
2016-04-15 |
2019-06-13 |
ジェネンテック, インコーポレイテッド |
がんをモニタリングし治療するための方法
|
ES2850428T3
(es)
|
2016-04-15 |
2021-08-30 |
Hoffmann La Roche |
Procedimientos de monitorización y tratamiento del cáncer
|
CN109328069B
(zh)
|
2016-04-15 |
2023-09-01 |
亿一生物医药开发(上海)有限公司 |
Il-22在治疗坏死性小肠结肠炎中的用途
|
KR20230051602A
(ko)
|
2016-04-15 |
2023-04-18 |
알파인 이뮨 사이언시즈, 인코포레이티드 |
Icos 리간드 변이체 면역조절 단백질 및 그의 용도
|
KR20190006495A
(ko)
|
2016-04-15 |
2019-01-18 |
알파인 이뮨 사이언시즈, 인코포레이티드 |
Cd80 변이체 면역조절 단백질 및 그의 용도
|
CA3021086C
(en)
|
2016-04-15 |
2023-10-17 |
Bioatla, Llc |
Anti-axl antibodies, antibody fragments and their immunoconjugates and uses thereof
|
UA123323C2
(uk)
|
2016-05-02 |
2021-03-17 |
Ф. Хоффманн-Ля Рош Аг |
Димерний злитий поліпептид
|
WO2017192589A1
(en)
|
2016-05-02 |
2017-11-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to influenza ha and their use and identification
|
EP3455252B1
(en)
|
2016-05-11 |
2022-02-23 |
F. Hoffmann-La Roche AG |
Modified anti-tenascin antibodies and methods of use
|
SI3455261T1
(sl)
|
2016-05-13 |
2023-01-31 |
Bioatla, Inc. |
Protitelesa proti ROR2, fragmenti protitelesa, njihovi imunokonjugati in uporabe le-teh
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
WO2017201449A1
(en)
|
2016-05-20 |
2017-11-23 |
Genentech, Inc. |
Protac antibody conjugates and methods of use
|
JP7022080B2
(ja)
|
2016-05-27 |
2022-02-17 |
ジェネンテック, インコーポレイテッド |
部位特異的抗体-薬物複合体の特徴付けのための生化学分析的方法
|
KR20190015351A
(ko)
|
2016-05-27 |
2019-02-13 |
티지 쎄라퓨틱스, 인코포레이티드 |
B-세포 증식성 장애를 치료하기 위한 항-cd20 항체, p13 키나제-델타 선택적 억제제 및 btk 억제제의 조합
|
TW201902512A
(zh)
|
2016-06-02 |
2019-01-16 |
瑞士商赫孚孟拉羅股份公司 |
治療方法
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
EP3464280B1
(en)
|
2016-06-06 |
2021-10-06 |
F. Hoffmann-La Roche AG |
Silvestrol antibody-drug conjugates and methods of use
|
CN109563160B
(zh)
|
2016-06-24 |
2023-02-28 |
豪夫迈·罗氏有限公司 |
抗聚泛素多特异性抗体
|
WO2018007314A1
(en)
|
2016-07-04 |
2018-01-11 |
F. Hoffmann-La Roche Ag |
Novel antibody format
|
WO2018014260A1
(en)
|
2016-07-20 |
2018-01-25 |
Nanjing Legend Biotech Co., Ltd. |
Multispecific antigen binding proteins and methods of use thereof
|
CN110088127A
(zh)
|
2016-07-28 |
2019-08-02 |
高山免疫科学股份有限公司 |
Cd155变体免疫调节蛋白及其用途
|
WO2018022945A1
(en)
|
2016-07-28 |
2018-02-01 |
Alpine Immune Sciences, Inc. |
Cd112 variant immunomodulatory proteins and uses thereof
|
US11471488B2
(en)
|
2016-07-28 |
2022-10-18 |
Alpine Immune Sciences, Inc. |
CD155 variant immunomodulatory proteins and uses thereof
|
CN110088133B
(zh)
|
2016-07-29 |
2023-12-08 |
朱诺治疗学股份有限公司 |
抗独特型抗体及相关方法
|
JP2019525934A
(ja)
|
2016-07-29 |
2019-09-12 |
イーライ リリー アンド カンパニー |
癌の治療に使用するためのメレスチニブおよび抗pd−l1または抗pd−1阻害剤を用いた組み合わせ治療
|
RU2019104730A
(ru)
|
2016-07-29 |
2020-08-28 |
Чугаи Сейяку Кабусики Кайся |
Биспецифическое антитело, обладающее повышенной активностью, альтернативной функции кофактора fviii
|
CN116251182A
(zh)
|
2016-08-05 |
2023-06-13 |
中外制药株式会社 |
用于预防或治疗il-8相关疾病的组合物
|
EP3494139B1
(en)
|
2016-08-05 |
2022-01-12 |
F. Hoffmann-La Roche AG |
Multivalent and multiepitopic anitibodies having agonistic activity and methods of use
|
JP7250674B2
(ja)
|
2016-08-08 |
2023-04-03 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
がんの治療及び診断方法
|
WO2018031662A1
(en)
|
2016-08-11 |
2018-02-15 |
Genentech, Inc. |
Pyrrolobenzodiazepine prodrugs and antibody conjugates thereof
|
JP7213549B2
(ja)
|
2016-08-22 |
2023-01-27 |
シーエイチオー ファーマ インコーポレイテッド |
抗体、結合性断片、および使用の方法
|
WO2018045379A1
(en)
|
2016-09-02 |
2018-03-08 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of treating b cell disorders
|
EP3510046A4
(en)
|
2016-09-07 |
2020-05-06 |
The Regents of the University of California |
ANTIBODIES AGAINST OXIDATION-SPECIFIC EPITOPES
|
CA3035976A1
(en)
|
2016-09-09 |
2018-03-15 |
Tg Therapeutics, Inc. |
Combination of an anti-cd20 antibody, pi3 kinase-delta inhibitor, and anti-pd-1 or anti-pd-l1 antibody for treating hematological cancers
|
SG10201607778XA
(en)
|
2016-09-16 |
2018-04-27 |
Chugai Pharmaceutical Co Ltd |
Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
|
CN109689682B
(zh)
|
2016-09-19 |
2022-11-29 |
豪夫迈·罗氏有限公司 |
基于补体因子的亲和层析
|
KR102557643B1
(ko)
|
2016-09-23 |
2023-07-20 |
제넨테크, 인크. |
아토피성 피부염을 치료하기 위한 il-13 길항제의 용도
|
CN110139873A
(zh)
|
2016-10-03 |
2019-08-16 |
朱诺治疗学股份有限公司 |
Hpv特异性结合分子
|
CN110139674B
(zh)
|
2016-10-05 |
2023-05-16 |
豪夫迈·罗氏有限公司 |
制备抗体药物缀合物的方法
|
AU2017339517B2
(en)
|
2016-10-06 |
2024-03-14 |
Foundation Medicine, Inc. |
Therapeutic and diagnostic methods for cancer
|
WO2018068201A1
(en)
|
2016-10-11 |
2018-04-19 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies and variants thereof against ctla-4
|
EP3532091A2
(en)
|
2016-10-29 |
2019-09-04 |
H. Hoffnabb-La Roche Ag |
Anti-mic antibidies and methods of use
|
AU2017355401A1
(en)
|
2016-11-02 |
2019-05-02 |
Jounce Therapeutics, Inc. |
Antibodies to PD-1 and uses thereof
|
US20190284261A1
(en)
*
|
2016-11-07 |
2019-09-19 |
The Trustees Of The University Of Pennsylvania |
Dna antibody constructs for use against lyme disease
|
AU2017361081A1
(en)
|
2016-11-15 |
2019-05-23 |
Genentech, Inc. |
Dosing for treatment with anti-CD20/anti-CD3 bispecific antibodies
|
ES2866348T3
(es)
|
2016-11-16 |
2021-10-19 |
Lilly Co Eli |
Terapia de combinación para el cáncer con mutación o mutaciones de omisión del exón 14 o fenotipo de omisión del exón 14
|
TW201829463A
(zh)
|
2016-11-18 |
2018-08-16 |
瑞士商赫孚孟拉羅股份公司 |
抗hla-g抗體及其用途
|
JOP20190100A1
(ar)
|
2016-11-19 |
2019-05-01 |
Potenza Therapeutics Inc |
بروتينات ربط مولد ضد مضاد لـ gitr وطرق استخدامها
|
AU2017361887B2
(en)
|
2016-11-21 |
2019-08-15 |
Cureab Gmbh |
Anti-GP73 antibodies and immunoconjugates
|
AU2017373884A1
(en)
|
2016-12-07 |
2019-05-30 |
Ac Immune Sa |
Anti-tau antibodies and methods of their use
|
CR20230163A
(es)
|
2016-12-07 |
2023-07-06 |
Genentech Inc |
ANTICUERPOS ANTITAU Y MÉTODOS DE USO (Divisional 2019-0271)
|
CA3043333A1
(en)
|
2016-12-07 |
2018-06-14 |
Molecular Templates, Inc. |
Shiga toxin a subunit effector polypeptides, shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugation
|
EP3551663A1
(en)
|
2016-12-12 |
2019-10-16 |
H. Hoffnabb-La Roche Ag |
Methods of treating cancer using anti-pd-l1 antibodies and antiandrogens
|
EP3559034B1
(en)
|
2016-12-20 |
2020-12-02 |
H. Hoffnabb-La Roche Ag |
Combination therapy of anti-cd20/anti-cd3 bispecific antibodies and 4-1bb (cd137) agonists
|
JOP20190134A1
(ar)
|
2016-12-23 |
2019-06-02 |
Potenza Therapeutics Inc |
بروتينات رابطة لمولد ضد مضادة لنيوروبيلين وطرق استخدامها
|
BR112019013189A2
(pt)
|
2017-01-03 |
2019-12-10 |
Hoffmann La Roche |
moléculas de ligação ao antígeno biespecífica, polinucleotídeo, célula hospedeira, método de produção da molécula de ligação ao antígeno biespecífica, composição farmacêutica, uso, métodos para inibir o crescimento de células tumorais em um indivíduo e para tratar o câncer ou uma doença infecciosa
|
TW201825515A
(zh)
|
2017-01-04 |
2018-07-16 |
美商伊繆諾金公司 |
Met抗體以及其免疫結合物及用途
|
TW201831517A
(zh)
|
2017-01-12 |
2018-09-01 |
美商優瑞科生物技術公司 |
靶向組織蛋白h3肽/mhc複合體之構築體及其用途
|
WO2018140427A1
(en)
|
2017-01-25 |
2018-08-02 |
Molecular Templates, Inc. |
Cell-targeting molecules comprising de-immunized, shiga toxin a subunit effectors and cd8+ t-cell epitopes
|
EP4223774A3
(en)
|
2017-01-31 |
2023-09-27 |
Chugai Seiyaku Kabushiki Kaisha |
A pharmaceutical composition for use in the treatment or prevention of a c5-related disease and a method for treating or preventing a c5-related disease
|
AR110873A1
(es)
|
2017-02-10 |
2019-05-08 |
Genentech Inc |
Anticuerpos contra triptasa, composiciones de estos y usos de estos
|
US11021535B2
(en)
|
2017-02-10 |
2021-06-01 |
The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use
|
TW201837467A
(zh)
|
2017-03-01 |
2018-10-16 |
美商建南德克公司 |
用於癌症之診斷及治療方法
|
EP3596116B1
(en)
|
2017-03-16 |
2023-09-06 |
Alpine Immune Sciences, Inc. |
Pd-l1 variant immunomodulatory proteins and uses thereof
|
AU2018235838B2
(en)
|
2017-03-16 |
2023-12-14 |
Alpine Immune Sciences, Inc. |
CD80 variant immunomodulatory proteins and uses thereof
|
US11732022B2
(en)
|
2017-03-16 |
2023-08-22 |
Alpine Immune Sciences, Inc. |
PD-L2 variant immunomodulatory proteins and uses thereof
|
MX2019011141A
(es)
|
2017-03-22 |
2019-11-05 |
Genentech Inc |
Composiciones de anticuerpo optimizadas para el tratamiento de trastornos oculares.
|
CR20190440A
(es)
|
2017-03-27 |
2019-11-12 |
Hoffmann La Roche |
Receptores de unión a antígeno mejorados
|
TW202400231A
(zh)
|
2017-03-28 |
2024-01-01 |
美商建南德克公司 |
治療神經退化性疾病之方法
|
CN110382542B
(zh)
|
2017-03-29 |
2023-06-09 |
豪夫迈·罗氏有限公司 |
针对共刺激性tnf受体的双特异性抗原结合分子
|
CN110573528B
(zh)
|
2017-03-29 |
2023-06-09 |
豪夫迈·罗氏有限公司 |
针对共刺激性tnf受体的双特异性抗原结合分子
|
JOP20190203A1
(ar)
|
2017-03-30 |
2019-09-03 |
Potenza Therapeutics Inc |
بروتينات رابطة لمولد ضد مضادة لـ tigit وطرق استخدامها
|
BR112019018767A2
(pt)
|
2017-04-03 |
2020-05-05 |
Hoffmann La Roche |
anticorpos, molécula de ligação ao antígeno biespecífica, um ou mais polinucleotídeos isolados, um ou mais vetores, célula hospedeira, método para produzir um anticorpo, composição farmacêutica, usos, método para tratar uma doença em um indivíduo e invenção
|
BR112019017753A2
(pt)
|
2017-04-04 |
2020-04-07 |
Hoffmann La Roche |
molécula biespecífica, polinucleotídeo, vetor, célula, métodos para a produção de uma molécula e para o tratamento de um indivíduo, composição e uso da molécula biespecífica
|
KR102346336B1
(ko)
|
2017-04-05 |
2022-01-04 |
에프. 호프만-라 로슈 아게 |
Pd1 및 lag3에 특이적으로 결합하는 이중특이적 항체
|
MX2019011916A
(es)
|
2017-04-05 |
2020-01-09 |
Hoffmann La Roche |
Anticuerpos anti-lag3.
|
MX2019012192A
(es)
|
2017-04-14 |
2020-01-21 |
Genentech Inc |
Métodos de diagnóstico y terapéuticos para el cáncer.
|
JP7248588B2
(ja)
|
2017-04-21 |
2023-03-29 |
ジェネンテック, インコーポレイテッド |
疾患の治療のためのklk5アンタゴニストの使用
|
WO2018200586A1
(en)
|
2017-04-26 |
2018-11-01 |
Eureka Therapeutics, Inc. |
Constructs specifically recognizing glypican 3 and uses thereof
|
US20220135670A1
(en)
|
2017-04-27 |
2022-05-05 |
Tesaro, Inc. |
Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof
|
MX2019013137A
(es)
|
2017-05-05 |
2020-07-14 |
Allakos Inc |
Metodos y composiciones para tratar enfermedades oculares alergicas.
|
KR102376863B1
(ko)
|
2017-05-12 |
2022-03-21 |
하푼 테라퓨틱스, 인크. |
메소텔린 결합 단백질
|
SG10202112636SA
(en)
|
2017-05-16 |
2021-12-30 |
Five Prime Therapeutics Inc |
Anti-fgfr2 antibodies in combination with chemotherapy agents in cancer treatment
|
BR112019024410A2
(pt)
|
2017-06-20 |
2020-07-14 |
Amgen Inc. |
método de tratamento ou melhoria de disfunções metabólicas usando proteínas de ligação para receptor do peptídeo inibidor gástrico (gipr) em combinação com agonistas de glp 1
|
JP2020527351A
(ja)
|
2017-07-21 |
2020-09-10 |
ジェネンテック, インコーポレイテッド |
がんの治療法及び診断法
|
WO2019020606A1
(en)
|
2017-07-26 |
2019-01-31 |
F. Hoffmann-La Roche Ag |
POLYTHERAPY WITH BET INHIBITOR, BCL-2 INHIBITOR AND ANTI-CD20 ANTIBODY
|
EP3658589B1
(en)
|
2017-07-26 |
2023-09-27 |
Forty Seven, Inc. |
Anti-sirp-alpha antibodies and related methods
|
CN111511762A
(zh)
|
2017-08-21 |
2020-08-07 |
天演药业公司 |
抗cd137分子及其用途
|
EP3684413A1
(en)
|
2017-09-20 |
2020-07-29 |
Chugai Seiyaku Kabushiki Kaisha |
Dosage regimen for combination therapy using pd-1 axis binding antagonists and gpc3 targeting agent
|
US11180541B2
(en)
|
2017-09-28 |
2021-11-23 |
Geltor, Inc. |
Recombinant collagen and elastin molecules and uses thereof
|
MX2020002710A
(es)
|
2017-09-29 |
2020-07-20 |
Chugai Pharmaceutical Co Ltd |
Molecula de union al antigeno multiespecifica que tiene actividad de sustitucion de la funcion de cofactor del factor viii de coagulacion de sangre (fviii) y formulacion farmaceutica que contiene tal molecula como ingrediente activo.
|
CA3080546A1
(en)
|
2017-10-03 |
2019-04-11 |
Juno Therapeutics, Inc. |
Hpv-specific binding molecules
|
EP3694870A1
(en)
|
2017-10-10 |
2020-08-19 |
Alpine Immune Sciences, Inc. |
Ctla-4 variant immunomodulatory proteins and uses thereof
|
CN111372950A
(zh)
|
2017-10-12 |
2020-07-03 |
免疫苏醒公司 |
Vegfr-抗体轻链融合蛋白
|
EA202090681A1
(ru)
|
2017-10-17 |
2020-07-21 |
Ризен Фармасьютикалз Са |
Модуляторы каналов crac для лечения рака пищевода
|
EA202090974A1
(ru)
|
2017-10-18 |
2020-08-05 |
Элпайн Иммьюн Сайенсиз, Инк. |
Вариантные иммуномодулирующие белки лиганда icos и сопутствующие композиции и способы
|
EP3697441B1
(en)
|
2017-10-20 |
2023-06-07 |
F. Hoffmann-La Roche AG |
Method for generating multispecific antibodies from monospecific antibodies
|
WO2019082124A1
(en)
|
2017-10-26 |
2019-05-02 |
Rhizen Pharmaceuticals Sa |
COMPOSITION AND METHOD FOR THE TREATMENT OF LARGE B-CELL DIFFUSED LYMPHOMA
|
CA3078676A1
(en)
|
2017-10-30 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
Method for in vivo generation of multispecific antibodies from monospecific antibodies
|
AU2018360367A1
(en)
|
2017-10-30 |
2020-05-28 |
Rhizen Pharmaceuticals Sa |
Calcium release-activated calcium channel modulators for treating hematological and solid cancers
|
CA3080904A1
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for b-cell maturation antigen
|
JP2021502066A
(ja)
|
2017-11-06 |
2021-01-28 |
ジェネンテック, インコーポレイテッド |
がんの診断及び療法
|
KR20200092328A
(ko)
|
2017-12-01 |
2020-08-03 |
화이자 인코포레이티드 |
항-cxcr5 항체 및 그의 조성물 및 용도
|
CN111770776A
(zh)
|
2017-12-06 |
2020-10-13 |
瑞真药业公司 |
治疗外周t细胞淋巴瘤和皮肤t细胞淋巴瘤的组合物和方法
|
MX2020006125A
(es)
|
2017-12-14 |
2020-08-24 |
Hoffmann La Roche |
Uso de un anticuerpo biespecifico de cea cd3 y un antagonista de la union al eje de pd-1 en un regimen de dosificacion para tratar el cancer.
|
EP3724225A1
(en)
|
2017-12-15 |
2020-10-21 |
Juno Therapeutics, Inc. |
Anti-cct5 binding molecules and methods of use thereof
|
MX2020006119A
(es)
|
2017-12-21 |
2020-08-24 |
Hoffmann La Roche |
Anticuerpos de union a hla-a2/wt1.
|
EP4219559A3
(en)
|
2017-12-22 |
2023-10-18 |
Jounce Therapeutics, Inc. |
Antibodies for lilrb2
|
EP3728321A1
(en)
|
2017-12-22 |
2020-10-28 |
F. Hoffmann-La Roche AG |
Use of pilra binding agents for treatment of a disease
|
KR20200104333A
(ko)
|
2017-12-28 |
2020-09-03 |
난징 레전드 바이오테크 씨오., 엘티디. |
Tigit에 대한 단일-도메인 항체 및 이의 변이체
|
KR20200104886A
(ko)
|
2017-12-28 |
2020-09-04 |
난징 레전드 바이오테크 씨오., 엘티디. |
Pd-l1에 대한 항체 및 변이체
|
CN111479588A
(zh)
|
2017-12-29 |
2020-07-31 |
豪夫迈·罗氏有限公司 |
用于改善抗vegf抗体的vegf受体阻断选择性的方法
|
EP3724223A1
(en)
|
2018-01-02 |
2020-10-21 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Neutralizing antibodies to ebola virus glycoprotein and their use
|
SG11202006148UA
(en)
|
2018-01-03 |
2020-07-29 |
Alpine Immune Sciences Inc |
Multi-domain immunomodulatory proteins and methods of use thereof
|
US20220153871A1
(en)
|
2018-01-04 |
2022-05-19 |
Iconic Therapeutics, Inc. |
Anti-Tissue Factor Antibodies, Antibody-Drug Conjugates, and Related Methods
|
EP3735422A1
(en)
|
2018-01-05 |
2020-11-11 |
AC Immune SA |
Misfolded tdp-43 binding molecules
|
US11713353B2
(en)
|
2018-01-15 |
2023-08-01 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies and variants thereof against PD-1
|
EP3740505A1
(en)
|
2018-01-16 |
2020-11-25 |
Lakepharma Inc. |
Bispecific antibody that binds cd3 and another target
|
PT3743088T
(pt)
|
2018-01-26 |
2022-12-05 |
Hoffmann La Roche |
Composições il-22 fc e métodos de utilização
|
MA51676A
(fr)
|
2018-01-26 |
2021-05-05 |
Hoffmann La Roche |
Protéines de fusion il-22 fc et procédés d'utilisation
|
CN116041516A
(zh)
|
2018-02-01 |
2023-05-02 |
信达生物制药(苏州)有限公司 |
全人源的抗b细胞成熟抗原(bcma)单链抗体及其应用
|
WO2019148445A1
(en)
|
2018-02-02 |
2019-08-08 |
Adagene Inc. |
Precision/context-dependent activatable antibodies, and methods of making and using the same
|
AU2019218959A1
(en)
|
2018-02-08 |
2020-09-03 |
Genentech, Inc. |
Bispecific antigen-binding molecules and methods of use
|
SG11202007564VA
(en)
|
2018-02-09 |
2020-09-29 |
Genentech Inc |
Therapeutic and diagnostic methods for mast cell-mediated inflammatory diseases
|
TWI829667B
(zh)
|
2018-02-09 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
結合gprc5d之抗體
|
CN111757894A
(zh)
|
2018-02-14 |
2020-10-09 |
Abba 疗法股份公司 |
抗人类pd-l2抗体
|
MX2020008502A
(es)
|
2018-02-21 |
2020-09-25 |
Genentech Inc |
Dosis para el tratamiento con proteinas de fusion il-22 fc.
|
AU2019226034A1
(en)
|
2018-02-21 |
2020-10-15 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to HIV-1 Env and their use
|
WO2019165434A1
(en)
|
2018-02-26 |
2019-08-29 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
WO2019175071A1
(en)
|
2018-03-13 |
2019-09-19 |
F. Hoffmann-La Roche Ag |
Therapeutic combination of 4-1 bb agonists with anti-cd20 antibodies
|
BR112020014591A2
(pt)
|
2018-03-14 |
2020-12-01 |
Beijing Xuanyi Pharmasciences Co., Ltd. |
anticorpos anticlaudina 18.2
|
US20200040103A1
(en)
|
2018-03-14 |
2020-02-06 |
Genentech, Inc. |
Anti-klk5 antibodies and methods of use
|
CA3093729A1
(en)
|
2018-03-15 |
2019-09-19 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-dengue virus antibodies having cross-reactivity to zika virus and methods of use
|
AU2019245243A1
(en)
|
2018-03-29 |
2020-09-03 |
Genentech, Inc |
Modulating lactogenic activity in mammalian cells
|
EP3774917A4
(en)
|
2018-03-30 |
2022-01-19 |
Nanjing Legend Biotech Co., Ltd. |
SINGLE DOMAIN ANTIBODIES AGAINST LAG-3 AND USES THEREOF
|
TW202011029A
(zh)
|
2018-04-04 |
2020-03-16 |
美商建南德克公司 |
偵測及定量fgf21之方法
|
CN112566698A
(zh)
|
2018-04-05 |
2021-03-26 |
朱诺治疗学股份有限公司 |
T细胞受体和表达该t细胞受体的工程化细胞
|
JP7323200B2
(ja)
|
2018-04-17 |
2023-08-08 |
モレキュラー テンプレーツ,インク. |
脱免疫化志賀毒素aサブユニット足場を含むher2ターゲティング分子
|
AR115052A1
(es)
|
2018-04-18 |
2020-11-25 |
Hoffmann La Roche |
Anticuerpos multiespecíficos y utilización de los mismos
|
AR114789A1
(es)
|
2018-04-18 |
2020-10-14 |
Hoffmann La Roche |
Anticuerpos anti-hla-g y uso de los mismos
|
CN110464842B
(zh)
|
2018-05-11 |
2022-10-14 |
信达生物制药(苏州)有限公司 |
包含抗pcsk9抗体的制剂及其用途
|
JP2021524756A
(ja)
|
2018-05-14 |
2021-09-16 |
ウェアウルフ セラピューティクス, インコーポレイテッド |
活性化可能なサイトカインポリペプチド及びその使用方法
|
ES2955511T3
(es)
|
2018-05-14 |
2023-12-04 |
Werewolf Therapeutics Inc |
Polipéptidos de interleucina 2 activables y métodos de uso de los mismos
|
WO2019235426A1
(ja)
|
2018-06-04 |
2019-12-12 |
中外製薬株式会社 |
細胞質内での半減期が変化した抗原結合分子
|
WO2019241758A1
(en)
|
2018-06-15 |
2019-12-19 |
Alpine Immune Sciences, Inc. |
Pd-1 variant immunomodulatory proteins and uses thereof
|
WO2019246557A1
(en)
|
2018-06-23 |
2019-12-26 |
Genentech, Inc. |
Methods of treating lung cancer with a pd-1 axis binding antagonist, a platinum agent, and a topoisomerase ii inhibitor
|
EP3818082A1
(en)
|
2018-07-04 |
2021-05-12 |
F. Hoffmann-La Roche AG |
Novel bispecific agonistic 4-1bb antigen binding molecules
|
WO2020014306A1
(en)
|
2018-07-10 |
2020-01-16 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
CA3104147A1
(en)
|
2018-07-18 |
2020-01-23 |
Genentech, Inc. |
Methods of treating lung cancer with a pd-1 axis binding antagonist, an antimetabolite, and a platinum agent
|
AU2019306628A1
(en)
|
2018-07-20 |
2021-02-11 |
Surface Oncology, Inc. |
Anti-CD112R compositions and methods
|
KR20210038697A
(ko)
|
2018-08-01 |
2021-04-07 |
추가이 세이야쿠 가부시키가이샤 |
C5-관련 질환의 치료 또는 예방용 의약 조성물 및 c5-관련 질환을 치료 또는 예방하기 위한 방법
|
WO2020027330A1
(ja)
|
2018-08-03 |
2020-02-06 |
中外製薬株式会社 |
互いに連結された2つの抗原結合ドメインを含む抗原結合分子
|
CA3051549A1
(en)
|
2018-08-09 |
2020-02-09 |
Regeneron Pharmaceuticals, Inc. |
Methods for assessing binding affinity of an antibody variant to the neonatal fc receptor
|
WO2020032230A1
(ja)
|
2018-08-10 |
2020-02-13 |
中外製薬株式会社 |
抗cd137抗原結合分子およびその使用
|
TW202021618A
(zh)
|
2018-08-17 |
2020-06-16 |
美商23與我有限公司 |
抗il1rap抗體及其使用方法
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
WO2020061376A2
(en)
|
2018-09-19 |
2020-03-26 |
Alpine Immune Sciences, Inc. |
Methods and uses of variant cd80 fusion proteins and related constructs
|
AU2019342099A1
(en)
|
2018-09-19 |
2021-04-08 |
Genentech, Inc. |
Therapeutic and diagnostic methods for bladder cancer
|
EP4249917A3
(en)
|
2018-09-21 |
2023-11-08 |
F. Hoffmann-La Roche AG |
Diagnostic methods for triple-negative breast cancer
|
JP7425049B2
(ja)
|
2018-09-25 |
2024-01-30 |
ハープーン セラピューティクス,インク. |
Dll3結合タンパク質および使用方法
|
JP2022502088A
(ja)
|
2018-09-27 |
2022-01-11 |
エクシリオ デベロップメント, インコーポレイテッド |
マスクされたサイトカインポリペプチド
|
JP7221379B2
(ja)
|
2018-10-01 |
2023-02-13 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
抗fapクローン212を含む二重特異性抗原結合分子
|
EP3861025A1
(en)
|
2018-10-01 |
2021-08-11 |
F. Hoffmann-La Roche AG |
Bispecific antigen binding molecules with trivalent binding to cd40
|
US20220010020A1
(en)
|
2018-10-05 |
2022-01-13 |
Five Prime Therapeutics, Inc. |
Anti-FGFR2 Antibody Formulations
|
WO2020080715A1
(ko)
|
2018-10-15 |
2020-04-23 |
연세대학교 산학협력단 |
생산성이 향상된 항체 및 이의 제조방법
|
WO2020081493A1
(en)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Pd-l1 binding proteins
|
MX2021004348A
(es)
|
2018-10-18 |
2021-05-28 |
Genentech Inc |
Procedimientos de diagnóstico y terapéuticos para el cáncer de riñón sarcomatoide.
|
RU2724469C2
(ru)
|
2018-10-31 |
2020-06-23 |
Закрытое Акционерное Общество "Биокад" |
Моноклональное антитело, которое специфически связывается с cd20
|
EP3873944A1
(en)
|
2018-10-31 |
2021-09-08 |
Bayer Aktiengesellschaft |
Reversal agents for neutralizing the therapeutic activity of anti-fxia antibodies
|
AU2019375413A1
(en)
|
2018-11-05 |
2021-05-27 |
Genentech, Inc. |
Methods of producing two chain proteins in prokaryotic host cells
|
EP3880714A4
(en)
|
2018-11-16 |
2022-07-20 |
Memorial Sloan Kettering Cancer Center |
ANTIBODIES TO MUCIN-16 AND METHODS OF USE THEREOF
|
KR20210096559A
(ko)
|
2018-11-27 |
2021-08-05 |
이노벤트 바이오로직스 (쑤저우) 컴퍼니, 리미티드 |
항IL-23p19 항체 및 이의 용도
|
JP2022510276A
(ja)
|
2018-11-30 |
2022-01-26 |
アルパイン イミューン サイエンシズ インコーポレイテッド |
Cd86バリアント免疫調節タンパク質およびその使用
|
KR20210100656A
(ko)
|
2018-12-05 |
2021-08-17 |
제넨테크, 인크. |
암 면역요법을 위한 진단 방법 및 조성물
|
MX2021006573A
(es)
|
2018-12-06 |
2021-07-15 |
Genentech Inc |
Tratamiento conjunto de linfoma difuso de linfocitos b grandes que comprende un inmunoconjugado anti-cd79b, un agente alquilante y un anticuerpo anti-cd20.
|
CN113227119A
(zh)
|
2018-12-10 |
2021-08-06 |
基因泰克公司 |
用于与含Fc的蛋白质进行位点特异性缀合的光交联肽
|
EP3898667A2
(en)
|
2018-12-20 |
2021-10-27 |
F. Hoffmann-La Roche AG |
Modified antibody fcs and methods of use
|
US20220089694A1
(en)
|
2018-12-20 |
2022-03-24 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Ebola virus glycoprotein-specific monoclonal antibodies and uses thereof
|
AR117327A1
(es)
|
2018-12-20 |
2021-07-28 |
23Andme Inc |
Anticuerpos anti-cd96 y métodos de uso de estos
|
CN113631714A
(zh)
|
2018-12-21 |
2021-11-09 |
豪夫迈·罗氏有限公司 |
使用凋亡抗性细胞系产生多肽的方法
|
TWI829831B
(zh)
|
2018-12-21 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
結合cd3之抗體
|
JP2022514950A
(ja)
|
2018-12-21 |
2022-02-16 |
23アンドミー・インコーポレイテッド |
抗il-36抗体およびその使用方法
|
AU2019406712A1
(en)
|
2018-12-21 |
2021-06-17 |
F. Hoffmann-La Roche Ag |
Antibody that binds to VEGF and IL-1beta and methods of use
|
EP3902833A2
(en)
|
2018-12-26 |
2021-11-03 |
City of Hope |
Activatable masked anti-ctla4 binding proteins
|
CN113272327A
(zh)
|
2018-12-30 |
2021-08-17 |
豪夫迈·罗氏有限公司 |
抗兔cd19抗体及其使用方法
|
AU2020208193A1
(en)
|
2019-01-14 |
2021-07-29 |
BioNTech SE |
Methods of treating cancer with a PD-1 axis binding antagonist and an RNA vaccine
|
CA3126778A1
(en)
|
2019-01-17 |
2020-07-23 |
Bayer Aktiengesellschaft |
Methods to determine whether a subject is suitable of being treated with an agonist of soluble guanylyl cyclase (sgc)
|
WO2020154405A2
(en)
|
2019-01-22 |
2020-07-30 |
Genentech, Inc. |
Immunoglobulin a antibodies and methods of production and use
|
EP3914615A1
(en)
|
2019-01-23 |
2021-12-01 |
F. Hoffmann-La Roche AG |
Methods of producing multimeric proteins in eukaryotic host cells
|
JPWO2020153467A1
(ja)
|
2019-01-24 |
2021-12-02 |
中外製薬株式会社 |
新規がん抗原及びそれらの抗原に対する抗体
|
PE20212198A1
(es)
|
2019-01-29 |
2021-11-16 |
Juno Therapeutics Inc |
Anticuerpos y receptores quimericos de antigenos especificos para receptor 1 huerfano tipo receptor tirosina-cinasa (ror1)
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
CN113710706A
(zh)
|
2019-02-27 |
2021-11-26 |
豪夫迈·罗氏有限公司 |
用于抗tigit抗体和抗cd20抗体或抗cd38抗体治疗的给药
|
MX2021010565A
(es)
|
2019-03-08 |
2021-10-13 |
Genentech Inc |
Metodos para detectar y cuantificar proteinas asociadas a la membrana en vesiculas extracelulares.
|
MA55296A
(fr)
|
2019-03-14 |
2022-03-23 |
Hoffmann La Roche |
Traitement du cancer avec des anticorps bispécifiques de her2xcd3 en combinaison avec un mab anti-her2
|
KR20210145152A
(ko)
|
2019-04-01 |
2021-12-01 |
제넨테크, 인크. |
단백질-함유 제제들의 안정화를 위한 조성물들 및 방법들
|
CN113993885A
(zh)
|
2019-04-12 |
2022-01-28 |
格尔托公司 |
重组弹性蛋白及其生产
|
MX2021012607A
(es)
|
2019-04-17 |
2022-03-11 |
Alpine Immune Sciences Inc |
Metodos y usos de proteinas de fusion de ligando icos (icosl) variante.
|
US20220298231A1
(en)
|
2019-04-18 |
2022-09-22 |
Ac Immune Sa |
Novel Molecules for Therapy and Diagnosis
|
TW202106876A
(zh)
|
2019-04-19 |
2021-02-16 |
日商中外製藥股份有限公司 |
辨識抗體改變部位之嵌合受體
|
CN114364703A
(zh)
|
2019-04-19 |
2022-04-15 |
豪夫迈·罗氏有限公司 |
抗mertk抗体及它们的使用方法
|
WO2020227228A2
(en)
|
2019-05-03 |
2020-11-12 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use
|
AU2020270376A1
(en)
|
2019-05-03 |
2021-10-07 |
Genentech, Inc. |
Methods of treating cancer with an anti-PD-L1 antibody
|
JP2022536602A
(ja)
|
2019-05-14 |
2022-08-18 |
ジェネンテック, インコーポレイテッド |
濾胞性リンパ腫を処置するための抗cd79b免疫複合体の使用方法
|
JP2022532217A
(ja)
|
2019-05-14 |
2022-07-13 |
ウェアウルフ セラピューティクス, インコーポレイテッド |
分離部分及びその使用方法
|
US20230085439A1
(en)
|
2019-05-21 |
2023-03-16 |
University Of Georgia Research Foundation, Inc. |
Antibodies that bind human metapneumovirus fusion protein and their use
|
SG11202112453TA
(en)
|
2019-05-23 |
2021-12-30 |
Ac Immune Sa |
Anti-tdp-43 binding molecules and uses thereof
|
CR20220008A
(es)
|
2019-06-10 |
2022-02-11 |
Chugai Pharmaceutical Co Ltd |
Molécula de unión al antígeno anti-células t para usarse en combinación con un inhibidor de citocinas
|
MX2022000174A
(es)
|
2019-07-02 |
2022-05-20 |
Us Health |
Anticuerpos monoclonales que se enlazan a egfrviii y sus usos.
|
AR119382A1
(es)
|
2019-07-12 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos de pre-direccionamiento y métodos de uso
|
JPWO2021010326A1
(zh)
|
2019-07-12 |
2021-01-21 |
|
|
AR119393A1
(es)
|
2019-07-15 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos que se unen a nkg2d
|
JP2022543553A
(ja)
|
2019-07-31 |
2022-10-13 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Gprc5dに結合する抗体
|
US20220275070A1
(en)
|
2019-07-31 |
2022-09-01 |
Hoffmann-La Roche Inc. |
Dosage and administration regimen for the treatment or prevention of c5-related diseases by the use of the anti-c5 antibody crovalimab
|
MX2022001153A
(es)
|
2019-07-31 |
2022-02-22 |
Hoffmann La Roche |
Regimen de dosificacion y administracion para el tratamiento o prevencion de enfermedades relacionadas con c5 mediante el uso del anticuerpo anti-c5 crovalimab.
|
JP2022543551A
(ja)
|
2019-07-31 |
2022-10-13 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Gprc5dに結合する抗体
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
TWI780464B
(zh)
|
2019-08-06 |
2022-10-11 |
香港商新旭生技股份有限公司 |
結合至病理性tau種類之抗體及其用途
|
KR20220062304A
(ko)
|
2019-09-12 |
2022-05-16 |
제넨테크, 인크. |
루푸스 신장염을 치료하는 조성물과 방법
|
TW202124442A
(zh)
*
|
2019-09-13 |
2021-07-01 |
大陸商北京軒義醫藥科技有限公司 |
人源化抗cldn18.2抗體、編碼其的核酸分子、其產生方法、包含其的組合物、試劑盒及其用途
|
US20210130492A1
(en)
|
2019-09-18 |
2021-05-06 |
Genentech, Inc. |
Anti-klk7 antibodies, anti-klk5 antibodies, multispecific anti-klk5/klk7 antibodies, and methods of use
|
KR20220066295A
(ko)
|
2019-09-20 |
2022-05-24 |
제넨테크, 인크. |
항트립타제 항체의 투약
|
WO2021059075A1
(en)
|
2019-09-27 |
2021-04-01 |
Janssen Biotech, Inc. |
Anti-ceacam antibodies and uses thereof
|
CR20220127A
(es)
|
2019-09-27 |
2022-05-27 |
Genentech Inc |
Administración de dosis para tratamiento con anticuerpos antagonistas anti-tigit y anti-pd-l1
|
JP7413519B2
(ja)
|
2019-10-18 |
2024-01-15 |
ジェネンテック, インコーポレイテッド |
びまん性大細胞型b細胞リンパ腫を処置するための抗cd79b免疫抱合体の使用方法
|
US20220387362A1
(en)
|
2019-10-21 |
2022-12-08 |
Rhizen Pharmaceuticals Ag |
Compositions comprising a dhodh inhibitor for the treatment of acute myeloid leukemia
|
US20220389103A1
(en)
|
2019-11-06 |
2022-12-08 |
Genentech, Inc. |
Diagnostic and therapeutic methods for treatment of hematologic cancers
|
EP4069734A1
(en)
|
2019-12-04 |
2022-10-12 |
AC Immune SA |
Novel molecules for therapy and diagnosis
|
WO2021113780A1
(en)
|
2019-12-06 |
2021-06-10 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to gprc5d-targeted binding domains and related compositions and methods
|
JP2023504740A
(ja)
|
2019-12-06 |
2023-02-06 |
ジュノー セラピューティクス インコーポレイテッド |
Bcma標的結合ドメインに対する抗イディオタイプ抗体ならびに関連する組成物および方法
|
PE20221511A1
(es)
|
2019-12-13 |
2022-10-04 |
Genentech Inc |
Anticuerpos anti-ly6g6d y metodos de uso
|
PE20221282A1
(es)
|
2019-12-18 |
2022-09-05 |
Hoffmann La Roche |
Anticuerpos que se unen a hla-a2/mage-a4
|
US20230058982A1
(en)
|
2019-12-27 |
2023-02-23 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-ctla-4 antibody and use thereof
|
CN113045655A
(zh)
|
2019-12-27 |
2021-06-29 |
高诚生物医药(香港)有限公司 |
抗ox40抗体及其用途
|
CA3160204A1
(en)
|
2020-01-06 |
2021-07-15 |
Vaccinex, Inc. |
Anti-ccr8 antibodies and uses thereof
|
CN110818795B
(zh)
|
2020-01-10 |
2020-04-24 |
上海复宏汉霖生物技术股份有限公司 |
抗tigit抗体和使用方法
|
WO2021194481A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
WO2022050954A1
(en)
|
2020-09-04 |
2022-03-10 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
TW202142257A
(zh)
|
2020-01-31 |
2021-11-16 |
美商建南德克公司 |
用pd-1軸結合拮抗劑及rna疫苗誘導新抗原決定基特異性t細胞之方法
|
CN115768800A
(zh)
|
2020-01-31 |
2023-03-07 |
克利夫兰诊所基金会 |
抗苗勒管激素受体2抗体和使用方法
|
TW202144395A
(zh)
|
2020-02-12 |
2021-12-01 |
日商中外製藥股份有限公司 |
用於癌症之治療的抗cd137抗原結合分子
|
US11692038B2
(en)
|
2020-02-14 |
2023-07-04 |
Gilead Sciences, Inc. |
Antibodies that bind chemokine (C-C motif) receptor 8 (CCR8)
|
WO2021168292A1
(en)
|
2020-02-20 |
2021-08-26 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Epstein-barr virus monoclonal antibodies and uses thereof
|
CN115151573A
(zh)
|
2020-02-28 |
2022-10-04 |
上海复宏汉霖生物技术股份有限公司 |
抗cd137构建体、多特异性抗体及其用途
|
WO2021170067A1
(zh)
|
2020-02-28 |
2021-09-02 |
上海复宏汉霖生物技术股份有限公司 |
抗cd137构建体及其用途
|
IL295979A
(en)
|
2020-03-06 |
2022-10-01 |
Ona Therapeutics S L |
Anti-cd36 antibodies and their use for cancer treatment
|
WO2021183849A1
(en)
|
2020-03-13 |
2021-09-16 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
EP4121163A1
(en)
|
2020-03-19 |
2023-01-25 |
Genentech, Inc. |
Isoform-selective anti-tgf-beta antibodies and methods of use
|
CA3169967A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Tie2-binding agents and methods of use
|
JP2023518841A
(ja)
|
2020-03-26 |
2023-05-08 |
ジェネンテック, インコーポレイテッド |
宿主細胞タンパク質が減少した修飾哺乳動物細胞
|
CN115397850A
(zh)
|
2020-03-30 |
2022-11-25 |
豪夫迈·罗氏有限公司 |
与vegf和pdgf-b结合的抗体及其使用方法
|
AR121706A1
(es)
|
2020-04-01 |
2022-06-29 |
Hoffmann La Roche |
Moléculas de unión a antígeno biespecíficas dirigidas a ox40 y fap
|
CN115698717A
(zh)
|
2020-04-03 |
2023-02-03 |
基因泰克公司 |
癌症的治疗和诊断方法
|
WO2021207662A1
(en)
|
2020-04-10 |
2021-10-14 |
Genentech, Inc. |
Use of il-22fc for the treatment or prevention of pneumonia, acute respiratory distress syndrome, or cytokine release syndrome
|
MX2022013173A
(es)
|
2020-04-24 |
2022-11-30 |
Hoffmann La Roche |
Modulacion de enzimas y vias con compuestos de sulfhidrilo y sus derivados.
|
TW202206111A
(zh)
|
2020-04-24 |
2022-02-16 |
美商建南德克公司 |
使用抗cd79b免疫結合物之方法
|
US20230167198A1
(en)
|
2020-04-27 |
2023-06-01 |
The Regents Of The University Of California |
Isoform-independent antibodies to lipoprotein(a)
|
EP4143345A1
(en)
|
2020-04-28 |
2023-03-08 |
Genentech, Inc. |
Methods and compositions for non-small cell lung cancer immunotherapy
|
TW202200212A
(zh)
|
2020-05-03 |
2022-01-01 |
中國大陸商聯寧(蘇州)生物製藥有限公司 |
包含抗-trop-2抗體之抗體藥物結合物
|
EP4146684A2
(en)
|
2020-05-08 |
2023-03-15 |
Alpine Immune Sciences, Inc. |
April and baff inhibitory immunomodulatory proteins with and without a t cell inhibitory protein and methods of use thereof
|
CN113993900B
(zh)
|
2020-05-27 |
2023-08-04 |
舒泰神(北京)生物制药股份有限公司 |
特异性识别神经生长因子的抗体及其用途
|
BR112022024339A2
(pt)
|
2020-05-29 |
2022-12-27 |
23Andme Inc |
Anticorpos anti cd200r1 e métodos de uso dos mesmos
|
CN116529260A
(zh)
|
2020-06-02 |
2023-08-01 |
当康生物技术有限责任公司 |
抗cd93构建体及其用途
|
EP4157462A1
(en)
|
2020-06-02 |
2023-04-05 |
Dynamicure Biotechnology LLC |
Anti-cd93 constructs and uses thereof
|
US20230340081A1
(en)
|
2020-06-08 |
2023-10-26 |
Hoffmann-La Roche Inc. |
Anti-hbv antibodies and methods of use
|
EP4165415A1
(en)
|
2020-06-12 |
2023-04-19 |
Genentech, Inc. |
Methods and compositions for cancer immunotherapy
|
KR20230025691A
(ko)
|
2020-06-16 |
2023-02-22 |
제넨테크, 인크. |
삼중 음성 유방암을 치료하기 위한 방법과 조성물
|
EP4168118A1
(en)
|
2020-06-18 |
2023-04-26 |
Genentech, Inc. |
Treatment with anti-tigit antibodies and pd-1 axis binding antagonists
|
WO2021255146A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3 and cea
|
AU2021291011A1
(en)
|
2020-06-19 |
2023-01-05 |
F. Hoffmann-La Roche Ag |
Antibodies binding to CD3 and CD19
|
WO2021255143A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3 and folr1
|
CR20230014A
(es)
|
2020-06-19 |
2023-02-17 |
Chugai Pharmaceutical Co Ltd |
Molécula de unión al antígeno anti-células t para usarse en combinación con un inhibidor de angiogénesis
|
AU2021291407A1
(en)
|
2020-06-19 |
2022-09-29 |
F. Hoffmann-La Roche Ag |
Antibodies binding to CD3
|
CN116234824A
(zh)
|
2020-06-22 |
2023-06-06 |
阿尔米雷尔有限公司 |
抗il-36抗体及其使用方法
|
JP2023532234A
(ja)
|
2020-06-22 |
2023-07-27 |
イノベント バイオロジクス(スーチョウ)カンパニー,リミティド |
抗cd73抗体とその用途
|
WO2021262783A1
(en)
|
2020-06-24 |
2021-12-30 |
Genentech, Inc. |
Apoptosis resistant cell lines
|
CA3182579A1
(en)
|
2020-07-07 |
2022-01-13 |
Ugur Sahin |
Therapeutic rna for hpv-positive cancer
|
CR20230076A
(es)
|
2020-07-10 |
2023-03-13 |
Hoffmann La Roche |
Anticuerpos que se unen a células cancerosas y dirigen radionucleótidos a dichas células
|
AU2021308653A1
(en)
|
2020-07-17 |
2023-02-16 |
Genentech, Inc. |
Anti-Notch2 antibodies and methods of use
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|
US20230322935A1
(en)
|
2020-07-29 |
2023-10-12 |
Dynamicure Biotechnology Llc |
Anti-cd93 constructs and uses thereof
|
JP2023536602A
(ja)
|
2020-08-03 |
2023-08-28 |
ジェネンテック, インコーポレイテッド |
リンパ腫のための診断及び治療方法
|
EP4192868A1
(en)
|
2020-08-05 |
2023-06-14 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to ror1-targeted binding domains and related compositions and methods
|
CA3188426A1
(en)
|
2020-08-07 |
2022-02-10 |
Yichin Liu |
Flt3 ligand fusion proteins and methods of use
|
TW202221026A
(zh)
|
2020-08-14 |
2022-06-01 |
瑞士商Ac 免疫有限公司 |
人源化抗tdp-43結合分子及其用途
|
WO2022036129A1
(en)
|
2020-08-14 |
2022-02-17 |
F. Hoffmann-La Roche Ag |
Methods for treating multiple sclerosis with ocrelizumab
|
EP4204448A2
(en)
|
2020-08-27 |
2023-07-05 |
cureab GmbH |
Anti-golph2 antibodies for macrophage and dendritic cell differentiation
|
KR20230056766A
(ko)
|
2020-08-28 |
2023-04-27 |
제넨테크, 인크. |
숙주 세포 단백질의 CRISPR/Cas9 다중 녹아웃
|
WO2022047316A1
(en)
|
2020-08-28 |
2022-03-03 |
Sana Biotechnology, Inc. |
Modified anti-viral binding agents
|
KR20230061458A
(ko)
|
2020-09-04 |
2023-05-08 |
에프. 호프만-라 로슈 아게 |
Vegf-a 및 ang2에 결합하는 항체 및 사용 방법
|
MX2023002901A
(es)
|
2020-09-14 |
2023-06-01 |
Ichnos Sciences SA |
Anticuerpos que se unen a la proteína auxiliar del receptor de interleucina-1 (il1rap) y usos de estos.
|
CA3194792A1
(en)
|
2020-09-15 |
2022-03-24 |
Bayer Aktiengesellschaft |
Novel anti-a2ap antibodies and uses thereof
|
US11795228B2
(en)
|
2020-09-30 |
2023-10-24 |
Dren Bio, Inc. |
Anti-CD94 antibodies and methods of use thereof
|
CN116406291A
(zh)
|
2020-10-05 |
2023-07-07 |
基因泰克公司 |
用抗fcrh5/抗cd3双特异性抗体进行治疗的给药
|
EP4229082A1
(en)
|
2020-10-16 |
2023-08-23 |
AC Immune SA |
Antibodies binding to alpha-synuclein for therapy and diagnosis
|
JP2023545566A
(ja)
|
2020-10-20 |
2023-10-30 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Pd-1軸結合アンタゴニストとlrrk2阻害剤との併用療法
|
EP4232475A1
(en)
|
2020-10-20 |
2023-08-30 |
Kantonsspital St. Gallen |
Antibodies or antigen-binding fragments specifically binding to gremlin-1 and uses thereof
|
TW202233671A
(zh)
|
2020-10-20 |
2022-09-01 |
美商建南德克公司 |
Peg結合抗mertk抗體及其使用方法
|
WO2022093981A1
(en)
|
2020-10-28 |
2022-05-05 |
Genentech, Inc. |
Combination therapy comprising ptpn22 inhibitors and pd-l1 binding antagonists
|
EP4240766A2
(en)
|
2020-11-04 |
2023-09-13 |
Genentech, Inc. |
Subcutaneous dosing of anti-cd20/anti-cd3 bispecific antibodies
|
JP2023548064A
(ja)
|
2020-11-04 |
2023-11-15 |
ジェネンテック, インコーポレイテッド |
抗cd20/抗cd3二重特異性抗体及び抗cd79b抗体薬物コンジュゲートによる処置のための投与
|
US20220162329A1
(en)
|
2020-11-04 |
2022-05-26 |
Genentech, Inc. |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies
|
US20220143026A1
(en)
|
2020-11-12 |
2022-05-12 |
Tg Therapeutics, Inc. |
Triple combination to treat b-cell malignancies
|
MX2023006650A
(es)
|
2020-12-07 |
2023-06-21 |
UCB Biopharma SRL |
Anticuerpos multiespecificos y combinaciones de anticuerpos.
|
BR112023008265A2
(pt)
|
2020-12-07 |
2024-02-06 |
UCB Biopharma SRL |
Anticorpos contra interleucina-22
|
TW202237639A
(zh)
|
2020-12-09 |
2022-10-01 |
日商武田藥品工業股份有限公司 |
鳥苷酸環化酶c(gcc)抗原結合劑之組成物及其使用方法
|
TW202237638A
(zh)
|
2020-12-09 |
2022-10-01 |
日商武田藥品工業股份有限公司 |
烏苷酸環化酶c(gcc)抗原結合劑之組成物及其使用方法
|
KR20230120665A
(ko)
|
2020-12-17 |
2023-08-17 |
에프. 호프만-라 로슈 아게 |
항-hla-g 항체 및 이의 용도
|
WO2022132904A1
(en)
|
2020-12-17 |
2022-06-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies targeting sars-cov-2
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性rna
|
CA3203257A1
(en)
|
2020-12-23 |
2022-06-30 |
Li Li |
Anti-b7-h3 antibody and uses thereof
|
WO2022140797A1
(en)
|
2020-12-23 |
2022-06-30 |
Immunowake Inc. |
Immunocytokines and uses thereof
|
MX2023007846A
(es)
|
2021-01-06 |
2023-07-07 |
F Hoffmann La Roche Ag |
Tratamiento conjunto que usa un anticuerpo biespecifico contra pd1-lag3 y un anticuerpo biespecifico de linfocitos t cd20.
|
AU2022207615A1
(en)
|
2021-01-12 |
2023-07-13 |
F. Hoffmann-La Roche Ag |
Split antibodies which bind to cancer cells and target radionuclides to said cells
|
EP4277668A1
(en)
|
2021-01-13 |
2023-11-22 |
F. Hoffmann-La Roche AG |
Combination therapy
|
WO2022162203A1
(en)
|
2021-01-28 |
2022-08-04 |
Vaccinvent Gmbh |
Method and means for modulating b-cell mediated immune responses
|
KR20230147099A
(ko)
|
2021-01-28 |
2023-10-20 |
백신벤트 게엠베하 |
B 세포 매개 면역 반응을 조절하기 위한 방법 및 수단(method and means for modulating b-cell mediated immune responses)
|
CN117120084A
(zh)
|
2021-01-28 |
2023-11-24 |
维肯芬特有限责任公司 |
用于调节b细胞介导的免疫应答的方法和手段
|
JP2024509695A
(ja)
|
2021-02-03 |
2024-03-05 |
ジェネンテック, インコーポレイテッド |
多重特異性結合タンパク質分解プラットフォームおよび使用方法
|
EP4288455A1
(en)
|
2021-02-03 |
2023-12-13 |
Mozart Therapeutics, Inc. |
Binding agents and methods of using the same
|
EP4291306A1
(en)
|
2021-02-09 |
2023-12-20 |
University of Georgia Research Foundation, Inc. |
Human monoclonal antibodies against pneumococcal antigens
|
US20240117011A1
(en)
|
2021-02-09 |
2024-04-11 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Antibodies targeting the spike protein of coronaviruses
|
JP2024506200A
(ja)
|
2021-02-15 |
2024-02-09 |
武田薬品工業株式会社 |
細胞治療用組成物及びtgf-bシグナル伝達を調節する方法
|
CA3211686A1
(en)
|
2021-02-26 |
2022-09-01 |
Bayer Aktiengesellschaft |
Inhibitors of il-11 or il-11ra for use in the treatment of abnormal uterine bleeding
|
EP4301781A1
(en)
|
2021-03-01 |
2024-01-10 |
Xilio Development, Inc. |
Combination of masked ctla4 and pd1/pdl1 antibodies for treating cancer
|
TW202317612A
(zh)
|
2021-03-01 |
2023-05-01 |
美商艾希利歐發展股份有限公司 |
用於治療癌症的ctla4及pd1/pdl1抗體之組合
|
JP2024509169A
(ja)
|
2021-03-03 |
2024-02-29 |
ソレント・セラピューティクス・インコーポレイテッド |
抗bcma抗体を含む抗体-薬物コンジュゲート
|
TW202302646A
(zh)
|
2021-03-05 |
2023-01-16 |
美商當康生物科技有限公司 |
抗vista構築體及其用途
|
IL305758A
(en)
|
2021-03-10 |
2023-11-01 |
Immunowake Inc |
Immunomodulatory compounds and their uses
|
AR125074A1
(es)
|
2021-03-12 |
2023-06-07 |
Genentech Inc |
Anticuerpos anti-klk7, anticuerpos anti-klk5, anticuerpos multiespecíficos anti-klk5 / klk7 y métodos de uso
|
IL305283A
(en)
|
2021-03-15 |
2023-10-01 |
Genentech Inc |
Compositions and methods for the treatment of lupus nephritis
|
WO2022197877A1
(en)
|
2021-03-19 |
2022-09-22 |
Genentech, Inc. |
Methods and compositions for time delayed bio-orthogonal release of cytotoxic agents
|
JP2024511424A
(ja)
|
2021-03-25 |
2024-03-13 |
ダイナミキュア バイオテクノロジー エルエルシー |
抗igfbp7構築物およびその使用
|
IL307233A
(en)
|
2021-03-30 |
2023-11-01 |
Bayer Ag |
Anti-SEMA3A antibodies and uses thereof
|
TW202304524A
(zh)
|
2021-04-10 |
2023-02-01 |
美商普方生物製藥美國公司 |
Folr1結合劑、其結合物及使用方法
|
AR125344A1
(es)
|
2021-04-15 |
2023-07-05 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-c1s
|
TW202305122A
(zh)
|
2021-04-19 |
2023-02-01 |
美商建南德克公司 |
經修飾之哺乳動物細胞
|
CN117222412A
(zh)
|
2021-04-23 |
2023-12-12 |
豪夫迈·罗氏有限公司 |
Nk细胞接合剂相关的不良反应的预防或减轻
|
EP4326768A1
(en)
|
2021-04-23 |
2024-02-28 |
Profoundbio Us Co. |
Anti-cd70 antibodies, conjugates thereof and methods of using the same
|
EP4330282A1
(en)
|
2021-04-30 |
2024-03-06 |
F. Hoffmann-La Roche AG |
Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate
|
AU2021443863A1
(en)
|
2021-04-30 |
2023-10-26 |
F. Hoffmann-La Roche Ag |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibody
|
AU2022268545A1
(en)
|
2021-05-03 |
2023-11-02 |
UCB Biopharma SRL |
Antibodies
|
WO2022236047A1
(en)
|
2021-05-07 |
2022-11-10 |
Viela Bio, Inc. |
Use of an anti-cd19 antibody to treat myasthenia gravis
|
AU2022269139A1
(en)
|
2021-05-07 |
2023-11-16 |
Alpine Immune Sciences, Inc. |
Methods of dosing and treatment with a taci-fc fusion immunomodulatory protein
|
IL308351A
(en)
|
2021-05-12 |
2024-01-01 |
Genentech Inc |
Methods for using anti-CD79B immunoconjugates to treat diffuse large B-cell lymphoma
|
BR112023023777A2
(pt)
|
2021-05-14 |
2024-01-30 |
Genentech Inc |
Anticorpos isolados, composição farmacêutica, ácido nucleico isolado, vetor isolado, célula hospedeira isolada, método para produzir um anticorpo, método para tratar uma condição associada à perda de função de trem2, método para reduzir os níveis de strem2 e uso de um anticorpo
|
KR20240010020A
(ko)
*
|
2021-05-18 |
2024-01-23 |
크리스티안-알브레히츠-우니버지태트 추 킬 |
공동-자극 다중 특이성 항체
|
WO2022243261A1
(en)
|
2021-05-19 |
2022-11-24 |
F. Hoffmann-La Roche Ag |
Agonistic cd40 antigen binding molecules targeting cea
|
KR20240010469A
(ko)
|
2021-05-21 |
2024-01-23 |
제넨테크, 인크. |
관심 재조합 생성물의 생성을 위한 변형된 세포
|
TW202306994A
(zh)
|
2021-06-04 |
2023-02-16 |
日商中外製藥股份有限公司 |
抗ddr2抗體及其用途
|
KR20240019109A
(ko)
|
2021-06-09 |
2024-02-14 |
에프. 호프만-라 로슈 아게 |
암의 치료에 이용하기 위한 특정 braf 억제제(패러독스 브레이크) 및 pd-1 축 결합 길항제의 조합물
|
WO2022262808A1
(en)
*
|
2021-06-16 |
2022-12-22 |
Biocytogen Pharmaceuticals (Beijing) Co., Ltd. |
Genetically modified non-human animal with human or chimeric cd20 genes
|
WO2022266660A1
(en)
|
2021-06-17 |
2022-12-22 |
Amberstone Biosciences, Inc. |
Anti-cd3 constructs and uses thereof
|
JP7472405B2
(ja)
|
2021-06-25 |
2024-04-22 |
中外製薬株式会社 |
抗ctla-4抗体
|
WO2022270612A1
(ja)
|
2021-06-25 |
2022-12-29 |
中外製薬株式会社 |
抗ctla-4抗体の使用
|
BR112023026966A2
(pt)
|
2021-07-02 |
2024-03-12 |
Hoffmann La Roche |
Métodos para tratar um indivíduo com melanoma, para alcançar uma resposta clínica, para tratar um indivíduo com linfoma não hodgkin, para tratar uma população de indivíduos com linfoma não hodgkin e para tratar um indivíduo com câncer colorretal metastático
|
TW202320857A
(zh)
|
2021-07-06 |
2023-06-01 |
美商普方生物製藥美國公司 |
連接子、藥物連接子及其結合物及其使用方法
|
WO2023283611A1
(en)
|
2021-07-08 |
2023-01-12 |
Staidson Biopharma Inc. |
Antibodies specifically recognizing tnfr2 and uses thereof
|
TW202306985A
(zh)
|
2021-07-12 |
2023-02-16 |
美商建南德克公司 |
降低抗體-脂酶結合之結構
|
AU2022312698A1
(en)
|
2021-07-13 |
2024-01-25 |
BioNTech SE |
Multispecific binding agents against cd40 and cd137 in combination therapy for cancer
|
TW202309097A
(zh)
|
2021-07-14 |
2023-03-01 |
美商建南德克公司 |
抗c-c模體趨化因子受體8(ccr8)抗體及其使用方法
|
CN115812082A
(zh)
|
2021-07-14 |
2023-03-17 |
舒泰神(北京)生物制药股份有限公司 |
特异性识别cd40的抗体及其应用
|
WO2023004386A1
(en)
|
2021-07-22 |
2023-01-26 |
Genentech, Inc. |
Brain targeting compositions and methods of use thereof
|
WO2023001884A1
(en)
|
2021-07-22 |
2023-01-26 |
F. Hoffmann-La Roche Ag |
Heterodimeric fc domain antibodies
|
AU2022317820A1
(en)
|
2021-07-28 |
2023-12-14 |
F. Hoffmann-La Roche Ag |
Methods and compositions for treating cancer
|
WO2023007472A1
(en)
|
2021-07-30 |
2023-02-02 |
ONA Therapeutics S.L. |
Anti-cd36 antibodies and their use to treat cancer
|
CN117897404A
(zh)
|
2021-08-02 |
2024-04-16 |
信达生物制药(苏州)有限公司 |
抗CD79b×CD3双特异性抗体及其用途
|
WO2023012147A1
(en)
|
2021-08-03 |
2023-02-09 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies and methods of use
|
WO2023019092A1
(en)
|
2021-08-07 |
2023-02-16 |
Genentech, Inc. |
Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma
|
WO2023019239A1
(en)
|
2021-08-13 |
2023-02-16 |
Genentech, Inc. |
Dosing for anti-tryptase antibodies
|
CN117858905A
(zh)
|
2021-08-19 |
2024-04-09 |
豪夫迈·罗氏有限公司 |
多价抗变体fc区抗体及使用方法
|
GB202111905D0
(en)
|
2021-08-19 |
2021-10-06 |
UCB Biopharma SRL |
Antibodies
|
AU2022332285A1
(en)
|
2021-08-23 |
2024-02-15 |
Immunitas Therapeutics, Inc. |
Anti-cd161 antibodies and uses thereof
|
WO2023028591A1
(en)
|
2021-08-27 |
2023-03-02 |
Genentech, Inc. |
Methods of treating tau pathologies
|
TW202325727A
(zh)
|
2021-08-30 |
2023-07-01 |
美商建南德克公司 |
抗聚泛素多特異性抗體
|
AU2022345251A1
(en)
|
2021-09-17 |
2024-03-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Synthetic humanized llama nanobody library and use thereof to identify sars-cov-2 neutralizing antibodies
|
WO2023056069A1
(en)
|
2021-09-30 |
2023-04-06 |
Angiex, Inc. |
Degrader-antibody conjugates and methods of using same
|
TW202321308A
(zh)
|
2021-09-30 |
2023-06-01 |
美商建南德克公司 |
使用抗tigit抗體、抗cd38抗體及pd—1軸結合拮抗劑治療血液癌症的方法
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
WO2023076876A1
(en)
|
2021-10-26 |
2023-05-04 |
Mozart Therapeutics, Inc. |
Modulation of immune responses to viral vectors
|
WO2023081818A1
(en)
|
2021-11-05 |
2023-05-11 |
American Diagnostics & Therapy, Llc (Adxrx) |
Monoclonal antibodies against carcinoembryonic antigens, and their uses
|
WO2023086807A1
(en)
|
2021-11-10 |
2023-05-19 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
TW202337494A
(zh)
|
2021-11-16 |
2023-10-01 |
美商建南德克公司 |
用莫蘇妥珠單抗治療全身性紅斑狼瘡(sle)之方法及組成物
|
AR127692A1
(es)
|
2021-11-16 |
2024-02-21 |
Ac Immune Sa |
Anticuerpos anti-asc para uso en tratamientos antiinflamatorios
|
WO2023094569A1
(en)
|
2021-11-26 |
2023-06-01 |
F. Hoffmann-La Roche Ag |
Combination therapy of anti-tyrp1/anti-cd3 bispecific antibodies and tyrp1-specific antibodies
|
AR127887A1
(es)
|
2021-12-10 |
2024-03-06 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y plap
|
TW202330582A
(zh)
|
2021-12-15 |
2023-08-01 |
美商建南德克公司 |
穩定的il-18多肽及其用途
|
AR128031A1
(es)
|
2021-12-20 |
2024-03-20 |
Hoffmann La Roche |
Anticuerpos agonistas anti-ltbr y anticuerpos biespecíficos que los comprenden
|
WO2023131901A1
(en)
|
2022-01-07 |
2023-07-13 |
Johnson & Johnson Enterprise Innovation Inc. |
Materials and methods of il-1beta binding proteins
|
US20230322958A1
(en)
|
2022-01-19 |
2023-10-12 |
Genentech, Inc. |
Anti-Notch2 Antibodies and Conjugates and Methods of Use
|
WO2023154678A1
(en)
*
|
2022-02-08 |
2023-08-17 |
Amgen Inc. |
Codon-optimized nucleic acids encoding ocrelizumab
|
WO2023154824A1
(en)
|
2022-02-10 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies that broadly target coronaviruses
|
TW202342519A
(zh)
|
2022-02-16 |
2023-11-01 |
瑞士商Ac 免疫有限公司 |
人源化抗tdp-43結合分子及其用途
|
TW202342520A
(zh)
|
2022-02-18 |
2023-11-01 |
美商樂天醫藥生技股份有限公司 |
抗計畫性死亡配體1(pd—l1)抗體分子、編碼多核苷酸及使用方法
|
WO2023172883A1
(en)
|
2022-03-07 |
2023-09-14 |
Alpine Immune Sciences, Inc. |
Immunomodulatory proteins of variant cd80 polypeptides, cell therapies thereof and related methods and uses
|
WO2023173026A1
(en)
|
2022-03-10 |
2023-09-14 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
WO2023178357A1
(en)
|
2022-03-18 |
2023-09-21 |
Evolveimmune Therapeutics, Inc. |
Bispecific antibody fusion molecules and methods of use thereof
|
TW202346365A
(zh)
|
2022-03-23 |
2023-12-01 |
瑞士商赫孚孟拉羅股份公司 |
抗cd20/抗cd3雙特異性抗體及化學療法之組合治療
|
WO2023192827A1
(en)
|
2022-03-26 |
2023-10-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Bispecific antibodies to hiv-1 env and their use
|
WO2023192881A1
(en)
|
2022-03-28 |
2023-10-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
WO2023186756A1
(en)
|
2022-03-28 |
2023-10-05 |
F. Hoffmann-La Roche Ag |
Interferon gamma variants and antigen binding molecules comprising these
|
WO2023191816A1
(en)
|
2022-04-01 |
2023-10-05 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2023194565A1
(en)
|
2022-04-08 |
2023-10-12 |
Ac Immune Sa |
Anti-tdp-43 binding molecules
|
WO2023198727A1
(en)
|
2022-04-13 |
2023-10-19 |
F. Hoffmann-La Roche Ag |
Pharmaceutical compositions of anti-cd20/anti-cd3 bispecific antibodies and methods of use
|
US20230406930A1
(en)
|
2022-04-13 |
2023-12-21 |
Genentech, Inc. |
Pharmaceutical compositions of therapeutic proteins and methods of use
|
WO2023203177A1
(en)
|
2022-04-20 |
2023-10-26 |
Kantonsspital St. Gallen |
Antibodies or antigen-binding fragments pan-specifically binding to gremlin-1 and gremlin-2 and uses thereof
|
WO2023215737A1
(en)
|
2022-05-03 |
2023-11-09 |
Genentech, Inc. |
Anti-ly6e antibodies, immunoconjugates, and uses thereof
|
WO2023219613A1
(en)
|
2022-05-11 |
2023-11-16 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2023217933A1
(en)
|
2022-05-11 |
2023-11-16 |
F. Hoffmann-La Roche Ag |
Antibody that binds to vegf-a and il6 and methods of use
|
WO2023235699A1
(en)
|
2022-05-31 |
2023-12-07 |
Jounce Therapeutics, Inc. |
Antibodies to lilrb4 and uses thereof
|
US11814439B1
(en)
|
2022-06-01 |
2023-11-14 |
Tg Therapeutics, Inc. |
Anti-CD20 antibody compositions
|
US11807689B1
(en)
|
2022-06-01 |
2023-11-07 |
Tg Therapeutics, Inc. |
Anti-CD20 antibody compositions
|
US11884740B1
(en)
|
2022-06-01 |
2024-01-30 |
Tg Therapeutics, Inc. |
Anti-CD20 antibody compositions
|
WO2023240058A2
(en)
|
2022-06-07 |
2023-12-14 |
Genentech, Inc. |
Prognostic and therapeutic methods for cancer
|
WO2023237706A2
(en)
|
2022-06-08 |
2023-12-14 |
Institute For Research In Biomedicine (Irb) |
Cross-specific antibodies, uses and methods for discovery thereof
|
WO2023239803A1
(en)
|
2022-06-08 |
2023-12-14 |
Angiex, Inc. |
Anti-tm4sf1 antibody-drug conjugates comprising cleavable linkers and methods of using same
|
WO2024015897A1
(en)
|
2022-07-13 |
2024-01-18 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2024020407A1
(en)
|
2022-07-19 |
2024-01-25 |
Staidson Biopharma Inc. |
Antibodies specifically recognizing b- and t-lymphocyte attenuator (btla) and uses thereof
|
WO2024020432A1
(en)
|
2022-07-19 |
2024-01-25 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2024020564A1
(en)
|
2022-07-22 |
2024-01-25 |
Genentech, Inc. |
Anti-steap1 antigen-binding molecules and uses thereof
|
WO2024030829A1
(en)
|
2022-08-01 |
2024-02-08 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies that bind to the underside of influenza viral neuraminidase
|
WO2024030956A2
(en)
|
2022-08-03 |
2024-02-08 |
Mozart Therapeutics, Inc. |
Cd39-specific binding agents and methods of using the same
|
WO2024028732A1
(en)
|
2022-08-05 |
2024-02-08 |
Janssen Biotech, Inc. |
Cd98 binding constructs for treating brain tumors
|
WO2024028731A1
(en)
|
2022-08-05 |
2024-02-08 |
Janssen Biotech, Inc. |
Transferrin receptor binding proteins for treating brain tumors
|
WO2024037633A2
(en)
|
2022-08-19 |
2024-02-22 |
Evive Biotechnology (Shanghai) Ltd |
Formulations comprising g-csf and uses thereof
|
WO2024044779A2
(en)
|
2022-08-26 |
2024-02-29 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for delta-like ligand 3 (dll3)
|
WO2024049949A1
(en)
|
2022-09-01 |
2024-03-07 |
Genentech, Inc. |
Therapeutic and diagnostic methods for bladder cancer
|
WO2024054929A1
(en)
|
2022-09-07 |
2024-03-14 |
Dynamicure Biotechnology Llc |
Anti-vista constructs and uses thereof
|
WO2024054822A1
(en)
|
2022-09-07 |
2024-03-14 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Engineered sars-cov-2 antibodies with increased neutralization breadth
|
WO2024064826A1
(en)
|
2022-09-22 |
2024-03-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use
|
WO2024077018A2
(en)
|
2022-10-04 |
2024-04-11 |
Alpine Immune Sciences, Inc. |
Methods and uses of taci-fc fusion immunomodulatory protein
|
WO2024077239A1
(en)
|
2022-10-07 |
2024-04-11 |
Genentech, Inc. |
Methods of treating cancer with anti-c-c motif chemokine receptor 8 (ccr8) antibodies
|