HK1208803A1 - Crystalline forms of a brutons tyrosine kinase inhibitor - Google Patents

Crystalline forms of a brutons tyrosine kinase inhibitor

Info

Publication number
HK1208803A1
HK1208803A1 HK15109505.2A HK15109505A HK1208803A1 HK 1208803 A1 HK1208803 A1 HK 1208803A1 HK 15109505 A HK15109505 A HK 15109505A HK 1208803 A1 HK1208803 A1 HK 1208803A1
Authority
HK
Hong Kong
Prior art keywords
tyrosine kinase
kinase inhibitor
crystalline forms
brutons tyrosine
brutons
Prior art date
Application number
HK15109505.2A
Other languages
English (en)
Chinese (zh)
Inventor
Mark Smyth
Erick Goldman
David D Wirth
Norbert Purro
Original Assignee
Pharmacyclics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49712527&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1208803(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacyclics Inc filed Critical Pharmacyclics Inc
Publication of HK1208803A1 publication Critical patent/HK1208803A1/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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HK15109505.2A 2012-06-04 2015-09-25 Crystalline forms of a brutons tyrosine kinase inhibitor HK1208803A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261655381P 2012-06-04 2012-06-04
PCT/US2013/043888 WO2013184572A1 (fr) 2012-06-04 2013-06-03 Formes cristallines d'un inhibiteur de tyrosine kinase de bruton

Publications (1)

Publication Number Publication Date
HK1208803A1 true HK1208803A1 (en) 2016-03-18

Family

ID=49712527

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15109505.2A HK1208803A1 (en) 2012-06-04 2015-09-25 Crystalline forms of a brutons tyrosine kinase inhibitor

Country Status (32)

Country Link
US (25) US9540382B2 (fr)
EP (1) EP2854859A4 (fr)
JP (8) JP6236071B2 (fr)
KR (7) KR20170091785A (fr)
CN (2) CN110354132A (fr)
AR (2) AR092844A1 (fr)
AU (6) AU2013271918C1 (fr)
BR (1) BR112014030424A8 (fr)
CA (4) CA2875986C (fr)
CL (3) CL2014003306A1 (fr)
CO (1) CO7240408A2 (fr)
CR (1) CR20140558A (fr)
DO (3) DOP2014000274A (fr)
EA (1) EA201492082A1 (fr)
EC (2) ECSP14033163A (fr)
GT (1) GT201400281A (fr)
HK (1) HK1208803A1 (fr)
IL (3) IL235894B (fr)
JO (2) JO3754B1 (fr)
MA (2) MA37711A1 (fr)
MX (2) MX348290B (fr)
MY (2) MY187999A (fr)
NZ (4) NZ737725A (fr)
PE (2) PE20190390A1 (fr)
PH (2) PH12014502681A1 (fr)
SG (2) SG10202101389TA (fr)
TN (1) TN2014000492A1 (fr)
TW (3) TWI662964B (fr)
UA (2) UA114421C2 (fr)
UY (2) UY39740A (fr)
WO (1) WO2013184572A1 (fr)
ZA (3) ZA202105174B (fr)

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KR101315610B1 (ko) 2006-09-22 2013-10-10 파마시클릭스, 인코포레이티드 브루톤 티로신 키나제 억제제
US20120101113A1 (en) 2007-03-28 2012-04-26 Pharmacyclics, Inc. Inhibitors of bruton's tyrosine kinase
ES2660418T3 (es) 2008-07-16 2018-03-22 Pharmacyclics Llc Inhibidores de la tirosina quinasa de Bruton para el tratamiento de tumores sólidos
US8491927B2 (en) * 2009-12-02 2013-07-23 Nimble Epitech, Llc Pharmaceutical composition containing a hypomethylating agent and a histone deacetylase inhibitor
CN107898791A (zh) 2010-06-03 2018-04-13 药品循环有限责任公司 布鲁顿酪氨酸激酶(btk)抑制剂的应用
MX356704B (es) 2011-01-11 2018-06-11 Novartis Ag Combinación.
KR20140048968A (ko) 2011-07-13 2014-04-24 파마시클릭스, 인코포레이티드 브루톤형 티로신 키나제의 억제제
JP6105578B2 (ja) 2011-07-21 2017-03-29 トレロ ファーマシューティカルズ， インコーポレイテッド 複素環式プロテインキナーゼ阻害剤
EA025437B1 (ru) 2011-12-11 2016-12-30 Ваймет Фармасьютикалс, Инк. Соединения, ингибирующие металлоферменты
US8377946B1 (en) 2011-12-30 2013-02-19 Pharmacyclics, Inc. Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors
CN110354132A (zh) 2012-06-04 2019-10-22 药品循环有限责任公司 布鲁顿酪氨酸激酶抑制剂的晶形
KR20150032340A (ko) 2012-07-24 2015-03-25 파마시클릭스, 인코포레이티드 브루톤 티로신 키나제(btk)의 억제제에 대한 내성과 관련된 돌연변이
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CA3218491A1 (fr) 2013-12-12
NZ713828A (en) 2017-05-26
TW201402122A (zh) 2014-01-16
IL254739A0 (en) 2017-11-30
US10294231B2 (en) 2019-05-21
AU2016250445A1 (en) 2016-11-17
US20200223856A1 (en) 2020-07-16
US20190248798A1 (en) 2019-08-15
DOP2022000096A (es) 2022-07-15
CA2875986A1 (fr) 2013-12-12
US20180170940A1 (en) 2018-06-21
JP6937086B6 (ja) 2021-10-27
US20150158871A1 (en) 2015-06-11
MX2014014848A (es) 2015-07-06
US20210070759A1 (en) 2021-03-11
TWI653041B (zh) 2019-03-11
US20170100404A1 (en) 2017-04-13
US20180179214A1 (en) 2018-06-28
MY187999A (en) 2021-11-08
US9296753B2 (en) 2016-03-29
WO2013184572A1 (fr) 2013-12-12
TWI662964B (zh) 2019-06-21
JP2019203008A (ja) 2019-11-28
CA3015208C (fr) 2024-01-02
JP2023162162A (ja) 2023-11-08
PE20190390A1 (es) 2019-03-13
KR20220093389A (ko) 2022-07-05
TW201906612A (zh) 2019-02-16
US20130338172A1 (en) 2013-12-19
GT201400281A (es) 2019-08-12
PH12020500028A1 (en) 2022-02-21
JP2018048182A (ja) 2018-03-29
IL235894A0 (en) 2015-01-29
EA201492082A1 (ru) 2015-03-31
JP6236071B2 (ja) 2017-11-22
EP2854859A1 (fr) 2015-04-08
NZ702548A (en) 2015-11-27
PE20150174A1 (es) 2015-02-12
ZA202303227B (en) 2024-01-31
US20180362535A1 (en) 2018-12-20
US20170334921A1 (en) 2017-11-23
AU2013271918B2 (en) 2016-08-04
MA37711A1 (fr) 2017-05-31
US9713617B2 (en) 2017-07-25
US10106548B2 (en) 2018-10-23
AR092844A1 (es) 2015-05-06
CN110354132A (zh) 2019-10-22
CA2991994A1 (fr) 2013-12-12
US9540382B2 (en) 2017-01-10
US9828383B1 (en) 2017-11-28
AR118108A2 (es) 2021-09-15
US20220112196A1 (en) 2022-04-14
US20190248799A1 (en) 2019-08-15
AU2013271918A1 (en) 2015-01-22
KR20200017549A (ko) 2020-02-18
MY194911A (en) 2022-12-22
JP2020015744A (ja) 2020-01-30
AU2023200435A1 (en) 2023-03-02
US20180362536A1 (en) 2018-12-20
KR20170091785A (ko) 2017-08-09
US10961251B1 (en) 2021-03-30
US9725455B1 (en) 2017-08-08
CL2017003496A1 (es) 2018-06-22
KR20190040370A (ko) 2019-04-17
KR20230170108A (ko) 2023-12-18
PH12014502681A1 (en) 2015-01-26
US20170305919A1 (en) 2017-10-26
US20180362534A1 (en) 2018-12-20
MA41654A1 (fr) 2018-07-31
JO3754B1 (ar) 2021-01-31
UA114421C2 (uk) 2017-06-12
US20180319806A1 (en) 2018-11-08
JP2018012710A (ja) 2018-01-25
NZ737725A (en) 2019-06-28
NZ731932A (en) 2018-09-28
AU2013271918A8 (en) 2015-02-26
IL235894B (en) 2020-03-31
US10266540B2 (en) 2019-04-23
BR112014030424A2 (pt) 2017-06-27
CA2875986C (fr) 2020-06-09
AU2020239751A1 (en) 2020-10-22
JP2021193095A (ja) 2021-12-23
CN104736178A (zh) 2015-06-24
MA41654B2 (fr) 2020-12-31
TWI662963B (zh) 2019-06-21
MX348290B (es) 2017-06-05
US20180327415A1 (en) 2018-11-15
CL2014003306A1 (es) 2015-04-17
AU2016250445B2 (en) 2018-07-26
KR20150015021A (ko) 2015-02-09
US10065968B2 (en) 2018-09-04
US20170226112A1 (en) 2017-08-10
CL2017000371A1 (es) 2017-10-30

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