PL2802314T3 - Sposób wytwarzania stabilnych, amorficznych hybrydowych nanocząstek zawierających co najmniej jeden inhibitor kinazy białkowej i co najmniej jeden polimerowy składnik stabilizujący i tworzący macierz - Google Patents

Sposób wytwarzania stabilnych, amorficznych hybrydowych nanocząstek zawierających co najmniej jeden inhibitor kinazy białkowej i co najmniej jeden polimerowy składnik stabilizujący i tworzący macierz

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Publication number
PL2802314T3
PL2802314T3 PL13736318T PL13736318T PL2802314T3 PL 2802314 T3 PL2802314 T3 PL 2802314T3 PL 13736318 T PL13736318 T PL 13736318T PL 13736318 T PL13736318 T PL 13736318T PL 2802314 T3 PL2802314 T3 PL 2802314T3
Authority
PL
Poland
Prior art keywords
matrix
protein kinase
kinase inhibitor
forming component
hybrid nanoparticles
Prior art date
Application number
PL13736318T
Other languages
English (en)
Inventor
Magnus Brisander
Mustafa Demirbüker
Gérald JESSON
Martin Malmsten
Helene Dérand
Original Assignee
Xspray Microparticles Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xspray Microparticles Ab filed Critical Xspray Microparticles Ab
Publication of PL2802314T3 publication Critical patent/PL2802314T3/pl

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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PL13736318T 2012-01-13 2013-01-11 Sposób wytwarzania stabilnych, amorficznych hybrydowych nanocząstek zawierających co najmniej jeden inhibitor kinazy białkowej i co najmniej jeden polimerowy składnik stabilizujący i tworzący macierz PL2802314T3 (pl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201261586187P 2012-01-13 2012-01-13
SE1250015 2012-01-13
US201261713120P 2012-10-12 2012-10-12
SE1251160 2012-10-12
EP13736318.0A EP2802314B1 (en) 2012-01-13 2013-01-11 A method for producing stable, amorphous hybrid nanoparticles comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix- forming component.
PCT/SE2013/050015 WO2013105894A1 (en) 2012-01-13 2013-01-11 A method for producing stable, amorphous hybrid nanoparticles comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix- forming component.

Publications (1)

Publication Number Publication Date
PL2802314T3 true PL2802314T3 (pl) 2021-06-14

Family

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Family Applications (3)

Application Number Title Priority Date Filing Date
PL17155686.3T PL3181122T3 (pl) 2012-01-13 2013-01-11 Kompozycja farmaceutyczna dazatynibu
PL13736318T PL2802314T3 (pl) 2012-01-13 2013-01-11 Sposób wytwarzania stabilnych, amorficznych hybrydowych nanocząstek zawierających co najmniej jeden inhibitor kinazy białkowej i co najmniej jeden polimerowy składnik stabilizujący i tworzący macierz
PL17155689.7T PL3181128T3 (pl) 2012-01-13 2013-01-11 Kompozycja farmaceutyczna nilotynibu

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL17155686.3T PL3181122T3 (pl) 2012-01-13 2013-01-11 Kompozycja farmaceutyczna dazatynibu

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL17155689.7T PL3181128T3 (pl) 2012-01-13 2013-01-11 Kompozycja farmaceutyczna nilotynibu

Country Status (15)

Country Link
US (19) US20140378454A1 (pl)
EP (7) EP4218740A1 (pl)
JP (13) JP6238311B2 (pl)
CN (4) CN104159577B (pl)
AU (8) AU2013208323B2 (pl)
CA (2) CA2860973C (pl)
DK (2) DK3181128T3 (pl)
ES (2) ES2946735T3 (pl)
FI (2) FI3181128T3 (pl)
HR (2) HRP20230529T1 (pl)
IL (4) IL293779B2 (pl)
IN (1) IN2014DN06529A (pl)
MX (3) MX347456B (pl)
PL (3) PL3181122T3 (pl)
WO (2) WO2013105895A1 (pl)

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