US5747498A
(en)
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
JP4464466B2
(ja)
|
1996-03-05 |
2010-05-19 |
アストラゼネカ・ユーケイ・リミテッド |
4―アニリノキナゾリン誘導体
|
PL190489B1
(pl)
|
1996-04-12 |
2005-12-30 |
Warner Lambert Co |
Nieodwracalne inhibitory kinaz tyrozyny, kompozycja farmaceutyczna je zawierająca i ich zastosowanie
|
GB9707800D0
(en)
|
1996-05-06 |
1997-06-04 |
Zeneca Ltd |
Chemical compounds
|
ATE229019T1
(de)
|
1996-06-27 |
2002-12-15 |
Janssen Pharmaceutica Nv |
N-4-(heteroarylmethyl)phenyl- heteroarylaminderivate
|
GB9718972D0
(en)
|
1996-09-25 |
1997-11-12 |
Zeneca Ltd |
Chemical compounds
|
NZ334125A
(en)
|
1996-09-25 |
2000-10-27 |
Zeneca Ltd |
Quinoline derivatives inhibiting the effect of growth factors such as VEGF
|
GB9708265D0
(en)
*
|
1997-04-24 |
1997-06-18 |
Nycomed Imaging As |
Contrast agents
|
ATE368665T1
(de)
|
1997-08-22 |
2007-08-15 |
Astrazeneca Ab |
Oxindolylchinazolinderivate als angiogenesehemmer
|
US6706721B1
(en)
|
1998-04-29 |
2004-03-16 |
Osi Pharmaceuticals, Inc. |
N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate
|
AU4317399A
(en)
|
1998-05-28 |
1999-12-13 |
Parker Hughes Institute |
Quinazolines for treating brain tumor
|
ATE459616T1
(de)
|
1998-08-11 |
2010-03-15 |
Novartis Ag |
Isochinoline derivate mit angiogenesis-hemmender wirkung
|
WO2000010981A1
(en)
*
|
1998-08-21 |
2000-03-02 |
Parker Hughes Institute |
Quinazoline derivatives
|
ID29800A
(id)
|
1999-02-27 |
2001-10-11 |
Boehringer Ingelheim Pharma |
Turunan-turunan 4-amino-kinazolin dan kinolin yang mempunyai efek inhibitor pada transduksi signal yang dimediasi oleh tirosin kinase
|
DE19911509A1
(de)
*
|
1999-03-15 |
2000-09-21 |
Boehringer Ingelheim Pharma |
Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
|
US6258820B1
(en)
|
1999-03-19 |
2001-07-10 |
Parker Hughes Institute |
Synthesis and anti-tumor activity of 6,7-dialkoxy-4-phenylamino-quinazolines
|
YU13200A
(sh)
|
1999-03-31 |
2002-10-18 |
Pfizer Products Inc. |
Postupci i intermedijeri za dobijanje anti-kancernih jedinjenja
|
US6126917A
(en)
*
|
1999-06-01 |
2000-10-03 |
Hadasit Medical Research Services And Development Ltd. |
Epidermal growth factor receptor binding compounds for positron emission tomography
|
US6933299B1
(en)
|
1999-07-09 |
2005-08-23 |
Smithkline Beecham Corporation |
Anilinoquinazolines as protein tyrosine kinase inhibitors
|
JP2003504363A
(ja)
|
1999-07-09 |
2003-02-04 |
グラクソ グループ リミテッド |
プロテインチロシンキナーゼ阻害剤としてのアニリノキナゾリン類
|
AU763242B2
(en)
*
|
1999-09-21 |
2003-07-17 |
Astrazeneca Ab |
Quinazoline compounds and pharmaceutical compositions containing them
|
RU2002110461A
(ru)
*
|
1999-09-21 |
2004-03-10 |
Астразенека Аб (Se) |
Производные хиназолина и их применение в качестве фармацевтических веществ
|
SE9903544D0
(sv)
|
1999-10-01 |
1999-10-01 |
Astra Pharma Prod |
Novel compounds
|
UA72946C2
(uk)
|
1999-11-05 |
2005-05-16 |
Астразенека Аб |
Похідні хіназоліну як інгібітори васкулярного ендотеліального фактора росту (vegf)
|
UA74803C2
(uk)
|
1999-11-11 |
2006-02-15 |
Осі Фармасьютікалз, Інк. |
Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
|
US7087613B2
(en)
|
1999-11-11 |
2006-08-08 |
Osi Pharmaceuticals, Inc. |
Treating abnormal cell growth with a stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride
|
GB2359551A
(en)
|
2000-02-23 |
2001-08-29 |
Astrazeneca Uk Ltd |
Pharmaceutically active pyrimidine derivatives
|
DE60112268T2
(de)
*
|
2000-03-06 |
2006-05-24 |
Astrazeneca Ab |
Verwendung von quinazolinderivate als inhibitoren der angiogenese
|
KR100675252B1
(ko)
*
|
2000-03-08 |
2007-02-08 |
한국생명공학연구원 |
신규 7,8-디히드로-잔테논-8-카르복실산 유도체 및 이를생산하는 신규 미생물
|
US20070021392A1
(en)
*
|
2000-03-31 |
2007-01-25 |
Davis Peter D |
Divided dose therapies with vascular damaging activity
|
GB0008269D0
(en)
*
|
2000-04-05 |
2000-05-24 |
Astrazeneca Ab |
Combination chemotherapy
|
JP4970689B2
(ja)
*
|
2000-04-07 |
2012-07-11 |
アストラゼネカ アクチボラグ |
キナゾリン化合物
|
UA73993C2
(uk)
|
2000-06-06 |
2005-10-17 |
Астразенека Аб |
Хіназолінові похідні для лікування пухлин та фармацевтична композиція
|
AR028948A1
(es)
|
2000-06-20 |
2003-05-28 |
Astrazeneca Ab |
Compuestos novedosos
|
TWI317285B
(en)
*
|
2000-07-28 |
2009-11-21 |
Dainippon Sumitomo Pharma Co |
New use and kit for remedies for cancer
|
CZ2003486A3
(cs)
|
2000-08-21 |
2003-05-14 |
Astrazeneca Ab |
Chinazolinové deriváty, způsob jejich přípravy a farmaceutický prostředek, který je obsahuje
|
US6403580B1
(en)
|
2000-08-26 |
2002-06-11 |
Boehringer Ingelheim Pharma Kg |
Quinazolines, pharmaceutical compositions containing these compounds, their use and processes for preparing them
|
DE10042058A1
(de)
*
|
2000-08-26 |
2002-03-07 |
Boehringer Ingelheim Pharma |
Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
|
US6740651B2
(en)
|
2000-08-26 |
2004-05-25 |
Boehringer Ingelheim Pharma Kg |
Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases
|
US6656946B2
(en)
|
2000-08-26 |
2003-12-02 |
Boehringer Ingelheim Pharma Kg |
Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases
|
US6617329B2
(en)
|
2000-08-26 |
2003-09-09 |
Boehringer Ingelheim Pharma Kg |
Aminoquinazolines and their use as medicaments
|
SE0003828D0
(sv)
|
2000-10-20 |
2000-10-20 |
Astrazeneca Ab |
Novel compounds
|
JP4564713B2
(ja)
|
2000-11-01 |
2010-10-20 |
ミレニアム・ファーマシューティカルズ・インコーポレイテッド |
窒素性複素環式化合物、ならびに窒素性複素環式化合物およびその中間体を作製するための方法
|
ATE430742T1
(de)
|
2000-12-21 |
2009-05-15 |
Smithkline Beecham Corp |
Pyrimidinamine als angiogenesemodulatoren
|
US6878714B2
(en)
|
2001-01-12 |
2005-04-12 |
Amgen Inc. |
Substituted alkylamine derivatives and methods of use
|
US6995162B2
(en)
|
2001-01-12 |
2006-02-07 |
Amgen Inc. |
Substituted alkylamine derivatives and methods of use
|
JP2002293773A
(ja)
*
|
2001-03-30 |
2002-10-09 |
Sumika Fine Chemicals Co Ltd |
キナゾリン誘導体の製造方法
|
WO2002092579A1
(en)
*
|
2001-05-14 |
2002-11-21 |
Astrazeneca Ab |
4-anilinoquinazoline derivatives
|
AU2002350105A1
(en)
|
2001-06-21 |
2003-01-08 |
Ariad Pharmaceuticals, Inc. |
Novel quinazolines and uses thereof
|
PL370137A1
(en)
*
|
2001-11-27 |
2005-05-16 |
Wyeth Holdings Corporation |
3-cyanoquinolines as inhibitors of egf-r and her2 kinases
|
US7268230B2
(en)
|
2002-02-01 |
2007-09-11 |
Astrazeneca Ab |
Quinazoline compounds
|
US6924285B2
(en)
|
2002-03-30 |
2005-08-02 |
Boehringer Ingelheim Pharma Gmbh & Co. |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
|
EP1521747B1
(en)
*
|
2002-07-15 |
2018-09-05 |
Symphony Evolution, Inc. |
Receptor-type kinase modulators and methods of use
|
GB0217431D0
(en)
|
2002-07-27 |
2002-09-04 |
Astrazeneca Ab |
Novel compounds
|
AU2003255819A1
(en)
|
2002-08-24 |
2004-03-11 |
Astrazeneca Ab |
Pyrimidine derivatives as modulators of chemokine receptor activity
|
GB0221828D0
(en)
|
2002-09-20 |
2002-10-30 |
Astrazeneca Ab |
Novel compound
|
PT1562955E
(pt)
|
2002-11-04 |
2008-05-05 |
Astrazeneca Ab |
Derivados de quinazolina como inibidores da scr tirosina-cinase
|
WO2004046101A2
(en)
*
|
2002-11-20 |
2004-06-03 |
Array Biopharma, Inc. |
Cyanoguanidines and cyanoamidines as erbb2 and egfr inhibitors
|
US7488823B2
(en)
*
|
2003-11-10 |
2009-02-10 |
Array Biopharma, Inc. |
Cyanoguanidines and cyanoamidines as ErbB2 and EGFR inhibitors
|
NZ540698A
(en)
|
2002-12-24 |
2008-05-30 |
Astrazeneca Ab |
Phosphonooxy quinazoline derivatives and their pharmaceutical use
|
KR20050122199A
(ko)
*
|
2003-01-23 |
2005-12-28 |
티.케이. 시그널 리미티드 |
표피성장인자 수용체 티로신 키나제의 비가역성 억제제 및 그의 용도
|
WO2004078723A1
(ja)
|
2003-03-07 |
2004-09-16 |
Santen Pharmaceutical Co. Ltd. |
4-ピリジルアルキルチオ基を置換基として有する新規化合物
|
GB0309850D0
(en)
|
2003-04-30 |
2003-06-04 |
Astrazeneca Ab |
Quinazoline derivatives
|
SE0301569D0
(sv)
|
2003-05-27 |
2003-05-27 |
Astrazeneca Ab |
Novel compounds
|
GB0317665D0
(en)
|
2003-07-29 |
2003-09-03 |
Astrazeneca Ab |
Qinazoline derivatives
|
GB0318423D0
(en)
*
|
2003-08-06 |
2003-09-10 |
Astrazeneca Ab |
Chemical compounds
|
CN102432552B
(zh)
|
2003-08-14 |
2016-01-20 |
阿雷生物药品公司 |
作为受体酪氨酸激酶抑制剂的喹唑啉类似物
|
US7501427B2
(en)
|
2003-08-14 |
2009-03-10 |
Array Biopharma, Inc. |
Quinazoline analogs as receptor tyrosine kinase inhibitors
|
DE602004022180D1
(de)
*
|
2003-09-16 |
2009-09-03 |
Astrazeneca Ab |
Chinazolinderivate
|
SI1667991T1
(sl)
|
2003-09-16 |
2008-10-31 |
Astrazeneca Ab |
Kinazolinski derivati kot inhibitorji tirozin kinaze
|
GB0322409D0
(en)
|
2003-09-25 |
2003-10-29 |
Astrazeneca Ab |
Quinazoline derivatives
|
EP2210607B1
(en)
|
2003-09-26 |
2011-08-17 |
Exelixis Inc. |
N-[3-fluoro-4-({6-(methyloxy)-7-[(3-morpholin-4-ylpropyl)oxy]quinolin-4-yl}oxy)phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide for the treatment of cancer
|
US7456189B2
(en)
|
2003-09-30 |
2008-11-25 |
Boehringer Ingelheim International Gmbh |
Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation
|
GB0326459D0
(en)
|
2003-11-13 |
2003-12-17 |
Astrazeneca Ab |
Quinazoline derivatives
|
AU2004293019B2
(en)
|
2003-11-19 |
2010-10-28 |
Array Biopharma Inc. |
Bicyclic inhibitors of MEK and methods of use thereof
|
GB0328243D0
(en)
|
2003-12-05 |
2004-01-07 |
Astrazeneca Ab |
Methods
|
JP2007517843A
(ja)
|
2004-01-05 |
2007-07-05 |
アストラゼネカ アクチボラグ |
Chk1阻害剤であるチオフェン誘導体
|
EP1713781B1
(en)
|
2004-02-03 |
2008-11-05 |
AstraZeneca AB |
Quinazoline derivatives
|
PL1717229T3
(pl)
|
2004-02-17 |
2011-11-30 |
Santen Pharmaceutical Co Ltd |
Nowy cykliczny związek mający grupę 4-pirydyloalkilotiolową z wprowadzoną do niej (nie)podstawioną grupą aminową
|
EP1746999B1
(en)
*
|
2004-05-06 |
2011-11-16 |
Warner-Lambert Company LLC |
4-phenylamino-quinazolin-6-yl-amides
|
SE0401657D0
(sv)
|
2004-06-24 |
2004-06-24 |
Astrazeneca Ab |
Chemical compounds
|
BRPI0514735B8
(pt)
|
2004-08-28 |
2021-05-25 |
Astrazeneca Ab |
derivados de pirimidino sulfonamida como moduladores do receptor de quimiocina.
|
DE602005026865D1
(de)
|
2004-12-14 |
2011-04-21 |
Astrazeneca Ab |
Pyrazolopyrimidinverbindungen als antitumormittel
|
AU2005319382B2
(en)
|
2004-12-21 |
2011-04-07 |
Astrazeneca Ab |
Antibodies directed to angiopoietin-2 and uses thereof
|
RS52061B
(en)
|
2005-02-04 |
2012-04-30 |
Astrazeneca Ab |
PIRAZOLYL-AMINOPYRIDINE DERIVATIVES USEFUL AS KINASE INHIBITORS
|
DE602006016564D1
(de)
|
2005-03-03 |
2010-10-14 |
Santen Pharmaceutical Co Ltd |
Neue cyclische verbindung mit chinolylalkylthiogruppe
|
ES2548729T3
(es)
|
2005-03-31 |
2015-10-20 |
Santen Pharmaceutical Co., Ltd. |
Nuevo compuesto cíclico que tiene grupo pirimidinilalquiltio
|
CN1858040B
(zh)
*
|
2005-05-08 |
2011-04-06 |
中国科学院上海药物研究所 |
5,8-二取代喹唑啉及其制备方法和用途
|
WO2006119676A1
(fr)
*
|
2005-05-12 |
2006-11-16 |
Wenlin Huang |
Procede de preparation de derives de quinazoline et application pour la fabrication pour le traitement d'une maladie tumorale
|
CN101175733A
(zh)
*
|
2005-05-12 |
2008-05-07 |
黄文林 |
一种酪氨酸激酶抑制剂、其制备方法及作为抗肿瘤药物的应用
|
WO2006119673A1
(fr)
*
|
2005-05-12 |
2006-11-16 |
Wenlin Huang |
Procede de preparation de derives de quinazoline et application pour la fabrication pour le traitement d’une maladie tumorale
|
WO2006119675A1
(fr)
*
|
2005-05-12 |
2006-11-16 |
Wenlin Huang |
Procede de preparation de derives de quinazoline et application pour la fabrication pour le traitement d'une maladie tumorale
|
TWI441637B
(zh)
|
2005-05-18 |
2014-06-21 |
Array Biopharma Inc |
Mek雜環抑制劑及其使用方法
|
CN1313449C
(zh)
*
|
2005-07-14 |
2007-05-02 |
沈阳中海生物技术开发有限公司 |
新的喹唑啉类衍生物、含有其的药物组合物以及它们的用途
|
RU2008105987A
(ru)
|
2005-07-21 |
2009-08-27 |
Астразенека Аб (Se) |
Новые пиперидиновые производные
|
TW200738634A
(en)
|
2005-08-02 |
2007-10-16 |
Astrazeneca Ab |
New salt
|
TW200738658A
(en)
|
2005-08-09 |
2007-10-16 |
Astrazeneca Ab |
Novel compounds
|
WO2007034144A1
(en)
|
2005-09-20 |
2007-03-29 |
Astrazeneca Ab |
4- (ih-indazol-s-yl-amino)-quinazoline compounds as erbb receptor tyrosine kinase inhibitors for the treatment of cancer
|
US20090099216A1
(en)
|
2005-09-22 |
2009-04-16 |
Astrazeneca Aktiebolag A Corporation Of Sweden |
Novel adenine compound
|
US20090105212A1
(en)
|
2005-09-22 |
2009-04-23 |
Dainippon Sumitomo Pharma Co., Ltd. a corporation of Japan |
Novel adenine compound
|
US20080269240A1
(en)
|
2005-09-22 |
2008-10-30 |
Dainippon Sumitomo Pharma Co., Ltd. a corporation of Japan |
Novel Adenine Compound
|
EP1939198A4
(en)
|
2005-09-22 |
2012-02-15 |
Dainippon Sumitomo Pharma Co |
NEW ADENINE CONNECTION
|
WO2007034817A1
(ja)
|
2005-09-22 |
2007-03-29 |
Dainippon Sumitomo Pharma Co., Ltd. |
新規アデニン化合物
|
WO2007039736A1
(en)
|
2005-10-06 |
2007-04-12 |
Astrazeneca Ab |
Novel compounds
|
US8247556B2
(en)
|
2005-10-21 |
2012-08-21 |
Amgen Inc. |
Method for preparing 6-substituted-7-aza-indoles
|
BRPI0618011A2
(pt)
|
2005-10-28 |
2011-08-16 |
Astrazeneca Ab |
composto ou um sal farmaceuticamente aceitável do mesmo, processo para a preparação do mesmo, composição farmacêutica, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, e, métodos para produzir um efeito anti-proliferativo e um efeito pró-apoptósico em um animal de sangue quente, para tratar doença e para produzir um efeito inibidor de jak em um animal de sangue quente
|
CA2755268C
(en)
|
2005-11-15 |
2013-12-31 |
Array Biopharma, Inc. |
Erbb inhibitors
|
TW200730512A
(en)
|
2005-12-12 |
2007-08-16 |
Astrazeneca Ab |
Novel compounds
|
RS52357B
(en)
|
2005-12-13 |
2012-12-31 |
Medimmune Limited |
BINDING PROTEINS SPECIFIC TO INSULIN SIMILAR GROWTH FACTORS AND THEIR USE
|
EP2305640A3
(en)
|
2005-12-15 |
2011-07-20 |
AstraZeneca AB |
Substituted diphenyl-ethers, -amines, -sulfides and -methanes for the treatment of respiratory diseases
|
TW200813091A
(en)
|
2006-04-10 |
2008-03-16 |
Amgen Fremont Inc |
Targeted binding agents directed to uPAR and uses thereof
|
JP2009538289A
(ja)
|
2006-05-26 |
2009-11-05 |
アストラゼネカ・アクチエボラーグ |
ビアリールまたはヘテロアリール置換インドール
|
CL2007002225A1
(es)
|
2006-08-03 |
2008-04-18 |
Astrazeneca Ab |
Agente de union especifico para un receptor del factor de crecimiento derivado de plaquetas (pdgfr-alfa); molecula de acido nucleico que lo codifica; vector y celula huesped que la comprenden; conjugado que comprende al agente; y uso del agente de un
|
DE102006037478A1
(de)
|
2006-08-10 |
2008-02-14 |
Merck Patent Gmbh |
2-(Heterocyclylbenzyl)-pyridazinonderivate
|
JP5227321B2
(ja)
|
2006-08-23 |
2013-07-03 |
クドス ファーマシューティカルズ リミテッド |
Mtor阻害剤としての2−メチルモルホリンピリド−、ピラゾ−及びピリミド−ピリミジン誘導体
|
KR20090077914A
(ko)
*
|
2006-09-11 |
2009-07-16 |
쿠리스 인코퍼레이션 |
항증식제로서의 다작용성 소분자
|
SG174774A1
(en)
*
|
2006-09-11 |
2011-10-28 |
Curis Inc |
Quinazoline based egfr inhibitors containing a zinc binding moiety
|
US7547781B2
(en)
*
|
2006-09-11 |
2009-06-16 |
Curis, Inc. |
Quinazoline based EGFR inhibitors containing a zinc binding moiety
|
EP1921070A1
(de)
|
2006-11-10 |
2008-05-14 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstelllung
|
TW200825084A
(en)
|
2006-11-14 |
2008-06-16 |
Astrazeneca Ab |
New compounds 521
|
US7799954B2
(en)
|
2006-11-17 |
2010-09-21 |
Abraxis Bioscience, Llc |
Dicarbonyl derivatives and methods of use
|
TW200831528A
(en)
|
2006-11-30 |
2008-08-01 |
Astrazeneca Ab |
Compounds
|
MX2009006018A
(es)
|
2006-12-19 |
2009-06-16 |
Astrazeneca Ab |
Derivados de quinuclidinol como antagonistas de receptores muscarinicos.
|
CL2008000191A1
(es)
|
2007-01-25 |
2008-08-22 |
Astrazeneca Ab |
Compuestos derivados de 4-amino-cinnotina-3-carboxamida; inhibidores de csf-1r quinasa; su proceso de preparacion; y su uso para tratar el cancer.
|
US8063034B2
(en)
|
2007-01-29 |
2011-11-22 |
Santen Pharmaceutical Co., Ltd. |
Oxadiazole derivatives and thiadiazole derivatives having neovascularization inhibitory activity
|
AU2008212999A1
(en)
|
2007-02-06 |
2008-08-14 |
Boehringer Ingelheim International Gmbh |
Bicyclic heterocycles, drugs containing said compounds, use thereof, and method for production thereof
|
US20080190689A1
(en)
*
|
2007-02-12 |
2008-08-14 |
Ballard Ebbin C |
Inserts for engine exhaust systems
|
JPWO2008114819A1
(ja)
|
2007-03-20 |
2010-07-08 |
大日本住友製薬株式会社 |
新規アデニン化合物
|
PE20081887A1
(es)
|
2007-03-20 |
2009-01-16 |
Dainippon Sumitomo Pharma Co |
Nuevo compuesto de adenina
|
UA99459C2
(xx)
|
2007-05-04 |
2012-08-27 |
Астразенека Аб |
ПОХІДНІ 9-(ПІРАЗОЛ-3-ІЛ)-9H-ПУРИН-2-АМІНУ І 3-(ПІРАЗОЛ-3-ІЛ)-3H-ІМІДАЗО$4,5-b]ПІРИДИН-5-АМІНУ ТА ЇХ ЗАСТОСУВАННЯ ДЛЯ ЛІКУВАННЯ РАКУ$ПРОИЗВОДНЫЕ 9-(ПИРАЗОЛ-3-ИЛ)-9H-ПУРИН-2-АМИНА И 3-(ПИРАЗОЛ-3-ИЛ)-3H-ИМИДАЗО$4,5-b]ПИРИДИН-5-АМИНА И ИХ ПРИМЕНЕНИЕ ДЛЯ ЛЕЧЕНИЯ РАКА
|
DE102007025718A1
(de)
|
2007-06-01 |
2008-12-04 |
Merck Patent Gmbh |
Pyridazinonderivate
|
DE102007025717A1
(de)
|
2007-06-01 |
2008-12-11 |
Merck Patent Gmbh |
Arylether-pyridazinonderivate
|
DE102007026341A1
(de)
|
2007-06-06 |
2008-12-11 |
Merck Patent Gmbh |
Benzoxazolonderivate
|
UA100983C2
(xx)
|
2007-07-05 |
2013-02-25 |
Астразенека Аб |
Біфенілоксипропанова кислота як модулятор crth2 і інтермедіати$бифенилоксипропановая кислота как модулятор crth2 и интермедиаты
|
DE102007032507A1
(de)
|
2007-07-12 |
2009-04-02 |
Merck Patent Gmbh |
Pyridazinonderivate
|
DE102007038957A1
(de)
|
2007-08-17 |
2009-02-19 |
Merck Patent Gmbh |
6-Thioxo-pyridazinderivate
|
DE102007041115A1
(de)
|
2007-08-30 |
2009-03-05 |
Merck Patent Gmbh |
Thiadiazinonderivate
|
WO2009035718A1
(en)
|
2007-09-10 |
2009-03-19 |
Curis, Inc. |
Tartrate salts or complexes of quinazoline based egfr inhibitors containing a zinc binding moiety
|
US8119616B2
(en)
*
|
2007-09-10 |
2012-02-21 |
Curis, Inc. |
Formulation of quinazoline based EGFR inhibitors containing a zinc binding moiety
|
AU2008306593C1
(en)
|
2007-10-04 |
2012-10-04 |
Astrazeneca Ab |
Steroidal [3, 2-C] pyrazole compounds, with glucocorticoid activity
|
CN101861321B
(zh)
|
2007-10-11 |
2013-02-06 |
阿斯利康(瑞典)有限公司 |
作为蛋白激酶b抑制剂的吡咯并[2,3-d]嘧啶衍生物
|
NZ585357A
(en)
|
2007-10-29 |
2012-02-24 |
Natco Pharma Ltd |
Novel 4-(tetrazol-5-yl)-quinazoline derivatives as anti cancer agents
|
CA2706571C
(en)
|
2007-12-19 |
2012-11-27 |
Genentech, Inc. |
5-anilinoimidazopyridines and methods of use
|
DE102007061963A1
(de)
|
2007-12-21 |
2009-06-25 |
Merck Patent Gmbh |
Pyridazinonderivate
|
RU2490278C2
(ru)
|
2007-12-21 |
2013-08-20 |
Медиммун Лимитед |
ЭЛЕМЕНТ, СВЯЗЫВАЮЩИЙСЯ С α-РЕЦЕПТОРОМ ИНТЕРЛЕЙКИНА-4 (IL-4Rα)-173
|
US8092804B2
(en)
|
2007-12-21 |
2012-01-10 |
Medimmune Limited |
Binding members for interleukin-4 receptor alpha (IL-4Rα)-173
|
KR20100099185A
(ko)
|
2007-12-21 |
2010-09-10 |
제넨테크, 인크. |
아자인돌리진 및 이용 방법
|
ME01461B
(me)
|
2008-02-07 |
2014-04-20 |
Boehringer Ingelheim Int |
Spirociklični heterocikli, ljekovi koji sadrže navedeno jedinjenje, njihova primjena i postupak za njihovu proizvodnju.
|
EP2254889B1
(en)
|
2008-02-28 |
2012-12-19 |
Merck Patent GmbH |
Protein kinase inhibitors and use thereof
|
DE102008019907A1
(de)
|
2008-04-21 |
2009-10-22 |
Merck Patent Gmbh |
Pyridazinonderivate
|
NZ589883A
(en)
|
2008-05-13 |
2012-06-29 |
Astrazeneca Ab |
Fumarate salt of 4- (3-chloro-2-fluoroanilino) -7-methoxy-6- { [1- (n-methylcarbamoylmethyl) piperidin- 4-yl] oxy} quinazoline
|
MX2010012492A
(es)
|
2008-05-27 |
2010-12-21 |
Astrazeneca Ab |
Derivados de fenoxipiridinilamida y su uso en el tratamiento de estados de enfermedad mediados por fosfodiesterasa 4.
|
DE102008025750A1
(de)
|
2008-05-29 |
2009-12-03 |
Merck Patent Gmbh |
Dihydropyrazolderivate
|
DE102008028905A1
(de)
|
2008-06-18 |
2009-12-24 |
Merck Patent Gmbh |
3-(3-Pyrimidin-2-yl-benzyl)-[1,2,4]triazolo[4,3-b]pyridazinderivate
|
DE102008029734A1
(de)
|
2008-06-23 |
2009-12-24 |
Merck Patent Gmbh |
Thiazolyl-piperidinderivate
|
CN101619043B
(zh)
*
|
2008-06-30 |
2013-06-05 |
和记黄埔医药(上海)有限公司 |
喹唑啉衍生物及其医药用途
|
TWI461423B
(zh)
|
2008-07-02 |
2014-11-21 |
Astrazeneca Ab |
用於治療Pim激酶相關病狀及疾病之噻唑啶二酮化合物
|
EP2313397B1
(de)
|
2008-08-08 |
2016-04-20 |
Boehringer Ingelheim International GmbH |
Cyclohexyloxy-substituierte heterocyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
|
DE102008037790A1
(de)
|
2008-08-14 |
2010-02-18 |
Merck Patent Gmbh |
Bicyclische Triazolderivate
|
DE102008038221A1
(de)
|
2008-08-18 |
2010-02-25 |
Merck Patent Gmbh |
7-Azaindolderivate
|
EP2927244A1
(en)
|
2008-09-19 |
2015-10-07 |
MedImmune, LLC |
Antibodies directed to DLL4 and uses thereof
|
DE102008052943A1
(de)
|
2008-10-23 |
2010-04-29 |
Merck Patent Gmbh |
Azaindolderivate
|
WO2010067102A1
(en)
|
2008-12-09 |
2010-06-17 |
Astrazeneca Ab |
Diazaspiro [5.5] undecane derivatives and related compounds as muscarinic-receptor antagonists and beta-adrenoreceptor agonists for the treatment of pulmonary disorders
|
US7863325B2
(en)
|
2008-12-11 |
2011-01-04 |
Axcentua Pharmaceuticals Ab |
Crystalline genistein sodium salt dihydrate
|
KR101849059B1
(ko)
|
2008-12-11 |
2018-04-13 |
악센투아 파마슈투칼스 아베 |
제니스테인의 결정성 형태
|
US20100152197A1
(en)
|
2008-12-15 |
2010-06-17 |
Astrazeneca Ab |
(4-tert-butylpiperazin-2-yl)(piperazin-1-yl)methanone-n-carboxamide derivatives
|
ES2550101T3
(es)
|
2008-12-17 |
2015-11-04 |
Merck Patent Gmbh |
Inhibidores de proteína quinasa de benzonaftiridinona tricíclica modificada con anillo C y su uso
|
JP2012512871A
(ja)
|
2008-12-18 |
2012-06-07 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
三環式アザインドール
|
DE102008063667A1
(de)
|
2008-12-18 |
2010-07-01 |
Merck Patent Gmbh |
3-(3-Pyrimidin-2-yl-benzyl)-°[1,2,4]triazolo[4,3-b]pyrimidin-derivate
|
DE102008062825A1
(de)
|
2008-12-23 |
2010-06-24 |
Merck Patent Gmbh |
3-(3-Pyrimidin-2-yl-benzyl)-[1,2,4]triazolo [4,3-b]pyridazin-derivate
|
DE102008062826A1
(de)
|
2008-12-23 |
2010-07-01 |
Merck Patent Gmbh |
Pyridazinonderivate
|
EP2379595A2
(en)
|
2008-12-23 |
2011-10-26 |
AstraZeneca AB |
Targeted binding agents directed to 5 1 and uses thereof
|
DE102009003954A1
(de)
|
2009-01-07 |
2010-07-08 |
Merck Patent Gmbh |
Pyridazinonderivate
|
DE102009003975A1
(de)
|
2009-01-07 |
2010-07-08 |
Merck Patent Gmbh |
Benzothiazolonderivate
|
DE102009004061A1
(de)
|
2009-01-08 |
2010-07-15 |
Merck Patent Gmbh |
Pyridazinonderivate
|
KR20200137052A
(ko)
|
2009-01-16 |
2020-12-08 |
엑셀리시스, 인코포레이티드 |
암의 치료를 위한 n-(4-{〔6,7-비스(메틸옥시)퀴놀린-4-일〕옥시}페닐)-n'-(4-플루오로페닐)사이클로프로판-1,1-디카르복사미드의 말산염 및 그 결정형
|
EP3360879A1
(en)
|
2009-02-05 |
2018-08-15 |
ImmunoGen, Inc. |
Benzodiazepine derivatives as cytotoxic agents
|
WO2010089580A1
(en)
|
2009-02-06 |
2010-08-12 |
Astrazeneca Ab |
Use of a mct1 inhibitor in the treatment of cancers expressing mct1 over mct4
|
PE20120603A1
(es)
|
2009-02-10 |
2012-06-14 |
Astrazeneca Ab |
Derivados de triazolo[4,3-b]piridazina y sus usos para el cancer de prostata
|
GB0905127D0
(en)
|
2009-03-25 |
2009-05-06 |
Pharminox Ltd |
Novel prodrugs
|
UY32520A
(es)
|
2009-04-03 |
2010-10-29 |
Astrazeneca Ab |
Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides
|
US8389580B2
(en)
|
2009-06-02 |
2013-03-05 |
Duke University |
Arylcyclopropylamines and methods of use
|
US20100317593A1
(en)
|
2009-06-12 |
2010-12-16 |
Astrazeneca Ab |
2,3-dihydro-1h-indene compounds
|
GB0913342D0
(en)
|
2009-07-31 |
2009-09-16 |
Astrazeneca Ab |
Compounds - 801
|
UA108618C2
(uk)
|
2009-08-07 |
2015-05-25 |
|
Застосування c-met-модуляторів в комбінації з темозоломідом та/або променевою терапією для лікування раку
|
DE102009043260A1
(de)
|
2009-09-28 |
2011-04-28 |
Merck Patent Gmbh |
Pyridinyl-imidazolonderivate
|
WO2011035540A1
(zh)
|
2009-09-28 |
2011-03-31 |
齐鲁制药有限公司 |
作为酪氨酸激酶抑制剂的4-(取代苯胺基)喹唑啉衍生物
|
WO2011039528A1
(en)
|
2009-10-02 |
2011-04-07 |
Astrazeneca Ab |
2-pyridone compounds used as inhibitors of neutrophil elastase
|
DE102009049679A1
(de)
|
2009-10-19 |
2011-04-21 |
Merck Patent Gmbh |
Pyrazolopyrimidinderivate
|
WO2011048409A1
(en)
|
2009-10-20 |
2011-04-28 |
Astrazeneca Ab |
Cyclic amine derivatives having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity
|
US8399460B2
(en)
|
2009-10-27 |
2013-03-19 |
Astrazeneca Ab |
Chromenone derivatives
|
ES2442797T3
(es)
|
2009-11-18 |
2014-02-13 |
Neomed Institute |
Compuestos de benzoimidazol y sus utilizaciones
|
CN102070608A
(zh)
*
|
2009-11-19 |
2011-05-25 |
天津药物研究院 |
4-取代苯胺基-7-取代烷氧基-喹唑啉衍生物、其制备方法和用途
|
NZ599405A
(en)
|
2009-11-24 |
2014-09-26 |
Medimmune Ltd |
Targeted binding agents against b7-h1
|
JP2013512859A
(ja)
|
2009-12-03 |
2013-04-18 |
大日本住友製薬株式会社 |
トール様受容体(tlr)を介して作用するイミダゾキノリン
|
ES2438509T3
(es)
|
2009-12-14 |
2014-01-17 |
Merck Patent Gmbh |
Inhibidores de la esfingosina quinasa
|
DE102009058280A1
(de)
|
2009-12-14 |
2011-06-16 |
Merck Patent Gmbh |
Thiazolderivate
|
JP2013514287A
(ja)
|
2009-12-17 |
2013-04-25 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
スフィンゴシンキナーゼの阻害薬
|
CN103980338B
(zh)
|
2010-01-15 |
2017-04-26 |
苏州润新生物科技有限公司 |
蟾蜍灵衍生物、其药物组合物及用途
|
CN102812017A
(zh)
|
2010-01-19 |
2012-12-05 |
阿斯利康(瑞典)有限公司 |
吡嗪衍生物
|
WO2011095807A1
(en)
|
2010-02-07 |
2011-08-11 |
Astrazeneca Ab |
Combinations of mek and hh inhibitors
|
CN102933231B
(zh)
|
2010-02-10 |
2015-07-29 |
伊缪诺金公司 |
Cd20抗体及其用途
|
WO2011114148A1
(en)
|
2010-03-17 |
2011-09-22 |
Astrazeneca Ab |
4h- [1, 2, 4] triazolo [5, 1 -b] pyrimidin-7 -one derivatives as ccr2b receptor antagonists
|
WO2011154677A1
(en)
|
2010-06-09 |
2011-12-15 |
Astrazeneca Ab |
Substituted n-[1-cyano-2-(phenyl)ethyl] 1-aminocycloalk-1-ylcarboxamide compounds - 760
|
GB201009801D0
(en)
|
2010-06-11 |
2010-07-21 |
Astrazeneca Ab |
Compounds 950
|
TW201219383A
(en)
|
2010-08-02 |
2012-05-16 |
Astrazeneca Ab |
Chemical compounds
|
TWI535712B
(zh)
|
2010-08-06 |
2016-06-01 |
阿斯特捷利康公司 |
化合物
|
DE102010034699A1
(de)
|
2010-08-18 |
2012-02-23 |
Merck Patent Gmbh |
Pyrimidinderivate
|
WO2012027957A1
(en)
|
2010-08-28 |
2012-03-08 |
Suzhou Neupharma Co., Ltd. |
Bufalin derivatives, pharmaceutical compositions and use thereof
|
GB201016442D0
(en)
|
2010-09-30 |
2010-11-17 |
Pharminox Ltd |
Novel acridine derivatives
|
DE102010048800A1
(de)
|
2010-10-20 |
2012-05-10 |
Merck Patent Gmbh |
Chinoxalinderivate
|
DE102010049595A1
(de)
|
2010-10-26 |
2012-04-26 |
Merck Patent Gmbh |
Chinazolinderivate
|
EP2640716A1
(en)
|
2010-11-19 |
2013-09-25 |
Dainippon Sumitomo Pharma Co., Ltd. |
Cyclic amide compounds and their use in the treatment of disease
|
WO2012066336A1
(en)
|
2010-11-19 |
2012-05-24 |
Astrazeneca Ab |
Benzylamine compounds as toll -like receptor 7 agonists
|
WO2012067269A1
(en)
|
2010-11-19 |
2012-05-24 |
Dainippon Sumitomo Pharma Co., Ltd. |
Aminoalkoxyphenyl compounds and their use in the treatment of disease
|
WO2012066335A1
(en)
|
2010-11-19 |
2012-05-24 |
Astrazeneca Ab |
Phenol compounds als toll -like receptor 7 agonists
|
JP5978225B2
(ja)
|
2010-12-16 |
2016-08-24 |
大日本住友製薬株式会社 |
治療に有用なイミダゾ[4,5−c]キノリン−1−イル誘導体
|
US8895570B2
(en)
|
2010-12-17 |
2014-11-25 |
Astrazeneca Ab |
Purine derivatives
|
CN102532103B
(zh)
*
|
2010-12-20 |
2014-07-09 |
天津药物研究院 |
喹唑啉芳基脲衍生物及其制备方法和用途
|
KR20140003467A
(ko)
|
2010-12-20 |
2014-01-09 |
메디뮨 리미티드 |
항il-18 항체 및 그의 용도
|
CN102558160B
(zh)
*
|
2010-12-20 |
2015-09-23 |
天津药物研究院 |
4-取代对甲磺酰胺苯胺基-喹唑啉衍生物及其制备方法和用途
|
EP3453714B1
(en)
|
2011-02-02 |
2020-11-04 |
Suzhou Neupharma Co., Ltd |
Cardenolide and bufadienolide 3-carbonate and 3-carbamate derivatives for the treatment of cancer and compositions thereof
|
MX346635B
(es)
|
2011-02-15 |
2017-03-27 |
Immunogen Inc |
Derivados citotoxicos de la benzodiazepina.
|
EP2675794B1
(en)
|
2011-02-17 |
2019-02-13 |
Cancer Therapeutics Crc Pty Limited |
Selective fak inhibitors
|
CA2827171C
(en)
|
2011-02-17 |
2019-04-09 |
Cancer Therapeutics Crc Pty Limited |
Fak inhibitors
|
GB201104267D0
(en)
|
2011-03-14 |
2011-04-27 |
Cancer Rec Tech Ltd |
Pyrrolopyridineamino derivatives
|
UY34013A
(es)
|
2011-04-13 |
2012-11-30 |
Astrazeneca Ab |
?compuestos de cromenona con actividad anti-tumoral?.
|
WO2012175991A1
(en)
|
2011-06-24 |
2012-12-27 |
Pharminox Limited |
Fused pentacyclic anti - proliferative compounds
|
WO2013003697A1
(en)
|
2011-06-30 |
2013-01-03 |
Trustees Of Boston University |
Method for controlling tumor growth, angiogenesis and metastasis using immunoglobulin containing and proline rich receptor-1 (igpr-1)
|
SG10201605619XA
(en)
|
2011-07-12 |
2016-08-30 |
Astrazeneca Ab |
N- (6- ( (2r,3s) -3,4-dihydroxybutan-2-yloxy) -2- (4 - fluorobenzylthio) pyrimidin- 4 - yl) -3- methylazetidine- 1 - sulfonamide as chemokine receptor modulator
|
CA2881993C
(en)
|
2011-07-27 |
2017-05-09 |
Astrazeneca Ab |
Substituted 4-methoxy-n3-(pyrimidin-2-yl)benzene-1,3-diamine compounds, and salts thereof
|
DE102011111400A1
(de)
|
2011-08-23 |
2013-02-28 |
Merck Patent Gmbh |
Bicyclische heteroaromatische Verbindungen
|
ES2725790T3
(es)
|
2011-08-26 |
2019-09-27 |
Neupharma Inc |
Algunas entidades químicas, composiciones, y métodos
|
EP2753174A4
(en)
|
2011-09-01 |
2015-05-20 |
Xiangping Qian |
PARTICULAR CHEMICAL ENTITIES, COMPOSITIONS AND METHODS
|
AU2012308238B2
(en)
|
2011-09-14 |
2017-05-25 |
Neupharma, Inc. |
Certain chemical entities, compositions, and methods
|
US9249110B2
(en)
|
2011-09-21 |
2016-02-02 |
Neupharma, Inc. |
Substituted quinoxalines as B-raf kinase inhibitors
|
US20140235573A1
(en)
|
2011-09-29 |
2014-08-21 |
The University Of Liverpool |
Prevention and/or treatment of cancer and/or cancer metastasis
|
US9249111B2
(en)
|
2011-09-30 |
2016-02-02 |
Neupharma, Inc. |
Substituted quinoxalines as B-RAF kinase inhibitors
|
US20130178520A1
(en)
|
2011-12-23 |
2013-07-11 |
Duke University |
Methods of treatment using arylcyclopropylamine compounds
|
WO2013112950A2
(en)
|
2012-01-25 |
2013-08-01 |
Neupharma, Inc. |
Certain chemical entities, compositions, and methods
|
JP6063482B2
(ja)
|
2012-01-28 |
2017-01-18 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung |
トリアゾロ[4,5−d]ピリミジン誘導体
|
BR112014017762A8
(pt)
|
2012-02-09 |
2017-07-11 |
Merck Patent Gmbh |
Derivados de furo[3,2-b]- e tieno[3,2-b]piridina como inibidores de tbk1 e ikk, seus usos, processo para a preparação dos mesmos e medicamentos que os compreendem
|
KR20140121477A
(ko)
|
2012-02-09 |
2014-10-15 |
메르크 파텐트 게엠베하 |
Tank 및 parp 저해체로서의 테트라히드로-퀴나졸리논
|
CN104254531B
(zh)
|
2012-02-21 |
2017-05-03 |
默克专利股份公司 |
环状二氨基嘧啶衍生物
|
CA2863717C
(en)
|
2012-02-21 |
2021-09-28 |
Lars Burgdorf |
Furopyridine derivatives
|
CN104114557B
(zh)
|
2012-02-21 |
2017-10-24 |
默克专利股份公司 |
作为syk酪氨酸激酶抑制剂和gcn2丝氨酸激酶抑制剂的8‑取代2‑氨基‑[1,2,4]***并[1,5‑a]吡嗪
|
CA2866450C
(en)
|
2012-03-07 |
2020-02-18 |
Merck Patent Gmbh |
Triazolopyrazine derivatives
|
US9193718B2
(en)
|
2012-03-26 |
2015-11-24 |
Fujian Institute Of Research On The Structure Of Matter, Chinese Academy Of Sciences |
Quinazoline derivative and application thereof
|
CN104169284B
(zh)
|
2012-03-28 |
2017-03-29 |
默克专利股份公司 |
双环吡嗪酮衍生物
|
WO2013144532A1
(en)
|
2012-03-30 |
2013-10-03 |
Astrazeneca Ab |
3 -cyano- 5 -arylamino-7 -cycloalkylaminopyrrolo [1, 5 -a] pyrimidine derivatives and their use as antitumor agents
|
SG11201406238UA
(en)
|
2012-04-05 |
2014-10-30 |
Hoffmann La Roche |
Bispecific antibodies against human tweak and human il17 and uses thereof
|
CN109354598A
(zh)
|
2012-04-29 |
2019-02-19 |
润新生物公司 |
化学个体、药物组合物及癌症治疗方法
|
HUE028325T2
(en)
|
2012-05-04 |
2016-12-28 |
Merck Patent Gmbh |
Pyrrolotriazines derivatives
|
AU2013270684B2
(en)
|
2012-06-08 |
2018-04-19 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
GB201211021D0
(en)
|
2012-06-21 |
2012-08-01 |
Cancer Rec Tech Ltd |
Pharmaceutically active compounds
|
DK2863955T3
(en)
|
2012-06-26 |
2017-01-23 |
Sutro Biopharma Inc |
MODIFIED FC PROTEINS, INCLUDING LOCATION-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES THEREOF, METHODS OF PRODUCING ITS AND PROCEDURES FOR USE THEREOF
|
CN104507957B
(zh)
|
2012-07-24 |
2018-12-25 |
默克专利股份有限公司 |
用于治疗关节病的羟基他汀衍生物
|
EP2882746B1
(en)
|
2012-08-07 |
2016-12-07 |
Merck Patent GmbH |
Pyridopyrimidine derivatives as protein kinase inhibitors
|
LT2882714T
(lt)
|
2012-08-08 |
2020-03-10 |
Merck Patent Gmbh |
(azo-)izochinolinono dariniai
|
US9238644B2
(en)
|
2012-08-17 |
2016-01-19 |
Cancer Therapeutics Crc Pty Limited |
VEGFR3 inhibitors
|
EP2887965A1
(en)
|
2012-08-22 |
2015-07-01 |
ImmunoGen, Inc. |
Cytotoxic benzodiazepine derivatives
|
ES2907763T3
(es)
|
2012-08-31 |
2022-04-26 |
Sutro Biopharma Inc |
Aminoácidos modificados que comprenden un grupo azido
|
WO2014041349A1
(en)
|
2012-09-12 |
2014-03-20 |
Cancer Therapeutics Crc Pty Ltd |
Tetrahydropyran-4-ylethylamino- or tetrahydropyranyl-4-ethyloxy-pyrimidines or -pyridazines as isoprenylcysteincarboxymethyl transferase inhibitors
|
CN104812389B
(zh)
|
2012-09-24 |
2020-07-17 |
润新生物公司 |
某些化学实体、组合物及方法
|
RU2650107C2
(ru)
|
2012-09-26 |
2018-04-09 |
Мерк Патент Гмбх |
Производные хиназолинона в качестве ингибиторов parp
|
AU2013334493B2
(en)
|
2012-10-26 |
2018-11-29 |
The University Of Queensland |
Use of endocytosis inhibitors and antibodies for cancer therapy
|
US10767229B2
(en)
|
2012-11-05 |
2020-09-08 |
Gmdx Co Pty Ltd |
Methods for determining the cause of somatic mutagenesis
|
EP2916838B1
(en)
|
2012-11-12 |
2019-03-13 |
Neupharma, Inc. |
Certain chemical entities, compositions, and methods
|
AU2013347232A1
(en)
|
2012-11-16 |
2015-07-02 |
Merck Patent Gmbh |
3-aminocyclopentane carboxamide derivatives
|
RU2656593C2
(ru)
|
2013-01-31 |
2018-06-06 |
Неомед Инститьют |
Соединения имидазопиридина, полезные при лечении состояния, связанного с активностью p2x3 и/или p2x2/3
|
CA2902080A1
(en)
|
2013-02-25 |
2014-08-28 |
Merck Patent Gmbh |
2-amino-3,4-dihydroquinazoline derivatives and the use thereof as cathepsin d inhibitors
|
JP6494533B2
(ja)
|
2013-02-28 |
2019-04-03 |
イミュノジェン・インコーポレーテッド |
細胞結合剤及び細胞毒性剤としてのマイタンシノイドを含む複合体
|
JP6423804B2
(ja)
|
2013-02-28 |
2018-11-14 |
イミュノジェン・インコーポレーテッド |
細胞結合剤及び細胞毒性剤を含む複合体
|
CN105026397B
(zh)
|
2013-03-05 |
2017-06-30 |
默克专利股份公司 |
作为抗癌剂的9‑(芳基或杂芳基)‑2‑(吡唑基、吡咯烷基或环戊基)氨基嘌呤衍生物
|
US9937137B2
(en)
|
2013-03-15 |
2018-04-10 |
Neurocentria, Inc. |
Magnesium compositions and uses thereof for cancers
|
WO2014161570A1
(en)
|
2013-04-03 |
2014-10-09 |
Roche Glycart Ag |
Antibodies against human il17 and uses thereof
|
WO2014194030A2
(en)
|
2013-05-31 |
2014-12-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
US20160115146A1
(en)
|
2013-06-07 |
2016-04-28 |
Universite Catholique De Louvain |
3-carboxy substituted coumarin derivatives with a potential utility for the treatment of cancer diseases
|
WO2014205511A1
(en)
|
2013-06-25 |
2014-12-31 |
University Of Canberra |
Methods and compositions for modulating cancer stem cells
|
ES2658039T3
(es)
|
2013-07-10 |
2018-03-08 |
Sutro Biopharma, Inc. |
Anticuerpos que comprenden múltiples residuos de aminoácidos no naturales sitio-específicos, métodos para su preparación y métodos de uso
|
HUE043465T2
(hu)
|
2013-08-23 |
2019-08-28 |
Neupharma Inc |
Kémiai anyagok, készítmények és módszerek
|
US10124001B2
(en)
|
2013-09-18 |
2018-11-13 |
University Of Canberra |
Stem cell modulation II
|
US20160298197A1
(en)
|
2013-10-01 |
2016-10-13 |
Queensland University Of Technology |
Kits and methods for diagnosis, screening, treatment and disease monitoring
|
WO2015054658A1
(en)
|
2013-10-11 |
2015-04-16 |
Sutro Biopharma, Inc. |
Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use
|
GB201321146D0
(en)
*
|
2013-11-29 |
2014-01-15 |
Cancer Rec Tech Ltd |
Quinazoline compounds
|
US8986691B1
(en)
|
2014-07-15 |
2015-03-24 |
Kymab Limited |
Method of treating atopic dermatitis or asthma using antibody to IL4RA
|
US8980273B1
(en)
|
2014-07-15 |
2015-03-17 |
Kymab Limited |
Method of treating atopic dermatitis or asthma using antibody to IL4RA
|
GB201403536D0
(en)
|
2014-02-28 |
2014-04-16 |
Cancer Rec Tech Ltd |
Inhibitor compounds
|
CN105330653A
(zh)
*
|
2014-08-11 |
2016-02-17 |
石药集团中奇制药技术(石家庄)有限公司 |
喹唑啉衍生物
|
AU2015309686B2
(en)
|
2014-08-25 |
2020-05-14 |
Epiaxis Therapeutics Pty Ltd |
Compositions for modulating cancer stem cells and uses therefor
|
CN107430126B
(zh)
|
2014-11-17 |
2019-12-06 |
昆士兰大学 |
食管腺癌和巴雷特食管的糖蛋白生物标志物及其用途
|
MA41179A
(fr)
|
2014-12-19 |
2017-10-24 |
Cancer Research Tech Ltd |
Composés inhibiteurs de parg
|
GB201501870D0
(en)
|
2015-02-04 |
2015-03-18 |
Cancer Rec Tech Ltd |
Autotaxin inhibitors
|
GB201502020D0
(en)
|
2015-02-06 |
2015-03-25 |
Cancer Rec Tech Ltd |
Autotaxin inhibitory compounds
|
AU2016220219B2
(en)
|
2015-02-17 |
2020-05-14 |
Neupharma, Inc. |
Certain chemical entities, compositions, and methods
|
GB201510019D0
(en)
|
2015-06-09 |
2015-07-22 |
Cancer Therapeutics Crc Pty Ltd |
Compounds
|
WO2017020065A1
(en)
|
2015-08-04 |
2017-02-09 |
University Of South Australia |
N-(pyridin-2-yl)-4-(thiazol-5-yl)pyrimidin-2-amine derivatives as therapeutic compounds
|
CN105153046A
(zh)
*
|
2015-08-25 |
2015-12-16 |
佛山市赛维斯医药科技有限公司 |
双卤素取代的乙氧基苯并喹唑啉类酪氨酸激酶抑制剂及用途
|
CN105153047A
(zh)
*
|
2015-08-25 |
2015-12-16 |
佛山市赛维斯医药科技有限公司 |
含新型苯并喹唑啉和邻位氟结构的酪氨酸激酶抑制剂及用途
|
EP3341496B1
(en)
|
2015-08-26 |
2021-02-24 |
GMDx Co Pty Ltd |
Methods of detecting cancer recurrence
|
GB201516504D0
(en)
|
2015-09-17 |
2015-11-04 |
Astrazeneca Ab |
Imadazo(4,5-c)quinolin-2-one Compounds and their use in treating cancer
|
EP3359526A4
(en)
|
2015-10-05 |
2019-04-03 |
The Trustees of Columbia University in the City of New York |
ACTIVATORS OF AUTOPHAGIC FLOW AND PHOSPHOLIPASE D AND CLAIRANCE OF PROTEIN AGGREGATES COMPRISING TAU AND TREATMENT OF PROTEINEOPATHIES
|
GB201519568D0
(en)
|
2015-11-05 |
2015-12-23 |
Astrazeneca Ab |
Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer
|
EP3390378B1
(en)
|
2015-12-17 |
2022-03-30 |
AlonBio Ltd. |
Small molecules against cancer
|
WO2017103932A1
(en)
|
2015-12-17 |
2017-06-22 |
Biokine Therapeutics Ltd. |
Small molecules for inhibiting chemokine activity, a kinase activity and/or cancer cells growth
|
WO2017122205A1
(en)
|
2016-01-13 |
2017-07-20 |
Hadasit Medical Research Services And Development Ltd. |
Radiolabeled erlotinib analogs and uses thereof
|
KR20180104106A
(ko)
|
2016-01-27 |
2018-09-19 |
서트로 바이오파마, 인크. |
anti-CD74 항체 접합체, anti-CD74 항체 접합체를 포함하는 조성물 및 anti-CD74 항체 접합체의 이용 방법
|
CN116082457A
(zh)
|
2016-02-01 |
2023-05-09 |
堪培拉大学 |
蛋白化合物及其用途
|
GB201604182D0
(en)
|
2016-03-11 |
2016-04-27 |
Astrazeneca Ab |
Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer
|
MA43733A
(fr)
|
2016-03-21 |
2018-11-28 |
Astrazeneca Ab |
Composés cinnolin-4-amine et leur utilisation pour traiter le cancer
|
BR112018070229A2
(pt)
|
2016-04-07 |
2019-01-29 |
Astrazeneca Ab |
óxido de n,n-dimetil-3-[[5-(3-metil-2-oxo-1-tetra-hidropiran-4-il-imidazo[4,5-c]quinolin-8-il)-2-piridil]óxi]propan-1-amina como modulador da cinase atm (mutada na ataxia telangiectasia) para tratamento do câncer
|
PL3442535T3
(pl)
|
2016-04-15 |
2022-10-24 |
Cancer Research Technology Limited |
Związki heterocykliczne jako inhibitory kinazy ret
|
GB2554333A
(en)
|
2016-04-26 |
2018-04-04 |
Big Dna Ltd |
Combination therapy
|
GB201608227D0
(en)
|
2016-05-11 |
2016-06-22 |
Astrazeneca Ab |
Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer
|
US10179787B2
(en)
|
2016-07-29 |
2019-01-15 |
Flx Bio, Inc. |
Chemokine receptor modulators and uses thereof
|
AU2017312561B2
(en)
|
2016-08-15 |
2022-06-30 |
Neupharma, Inc. |
Certain chemical entities, compositions, and methods
|
WO2018045379A1
(en)
|
2016-09-02 |
2018-03-08 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of treating b cell disorders
|
US10919896B2
(en)
|
2016-09-22 |
2021-02-16 |
Cancer Research Technology Limited |
Preparation and uses of pyrimidinone derivatives
|
GB201617103D0
(en)
|
2016-10-07 |
2016-11-23 |
Cancer Research Technology Limited |
Compound
|
EP3548478B1
(en)
|
2016-12-05 |
2021-11-17 |
Apros Therapeutics, Inc. |
Pyrimidine compounds containing acidic groups
|
US10786502B2
(en)
|
2016-12-05 |
2020-09-29 |
Apros Therapeutics, Inc. |
Substituted pyrimidines containing acidic groups as TLR7 modulators
|
JOP20190151B1
(ar)
|
2016-12-20 |
2023-09-17 |
Astrazeneca Ab |
مركبات أمينو - ترايازولو بيريدين واستخدامها في علاج سرطان
|
JP7113528B2
(ja)
|
2017-02-01 |
2022-08-05 |
オーセントラ セラピュティクス ピーティーワイ エルティーディー |
治療薬としてのN-シクロアルキル/ヘテロシクロアルキル-4-(イミダゾ[1,2-a]ピリジン)ピリミジン-2-アミン誘導体
|
US10703723B2
(en)
|
2017-03-09 |
2020-07-07 |
Truly Translational Sweden Ab |
Prodrugs of sulfasalazine, pharmaceutical compositions thereof and their use in the treatment of autoimmune disease
|
JOP20190209A1
(ar)
|
2017-03-16 |
2019-09-12 |
Astrazeneca Ab |
مركبات إيميدازو [ 4، 5-c ] كينولين-2-أون ديوترومية واستخدامها في علاج السرطان
|
GB201704325D0
(en)
|
2017-03-17 |
2017-05-03 |
Argonaut Therapeutics Ltd |
Compounds
|
GB201705971D0
(en)
|
2017-04-13 |
2017-05-31 |
Cancer Res Tech Ltd |
Inhibitor compounds
|
CN108864079B
(zh)
|
2017-05-15 |
2021-04-09 |
深圳福沃药业有限公司 |
一种三嗪化合物及其药学上可接受的盐
|
EP3630749B1
(en)
|
2017-05-26 |
2024-01-10 |
Cancer Research Technology Limited |
2-quinolone derived inhibitors of bcl6
|
WO2018220101A1
(en)
|
2017-05-31 |
2018-12-06 |
Truly Translational Sweden Ab |
A pharmaceutical composition comprising a combination of methotrexate and novobiocin, and the use of said composition in therapy
|
US11400160B2
(en)
|
2017-07-05 |
2022-08-02 |
E.P.O.S Iasis Research And Development Limited |
Multifunctional conjugates
|
WO2019023316A1
(en)
|
2017-07-26 |
2019-01-31 |
Sutro Biopharma, Inc. |
METHODS OF USING ANTI-CD74 ANTIBODIES AND ANTIBODY CONJUGATES IN THE TREATMENT OF A T CELL LYMPHOMA
|
EP3661941B1
(en)
|
2017-08-01 |
2022-12-14 |
Merck Patent GmbH |
Thiazolopyridine derivatives as adenosine receptor antagonists
|
WO2019034890A1
(en)
|
2017-08-18 |
2019-02-21 |
Cancer Research Technology Limited |
PYRROLO [2,3-B] PYRIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER
|
KR20200043434A
(ko)
|
2017-08-21 |
2020-04-27 |
메르크 파텐트 게엠베하 |
아데노신 수용체 길항제로서의 퀴녹살린 유도체
|
TWI791593B
(zh)
|
2017-08-21 |
2023-02-11 |
德商馬克專利公司 |
做為腺苷受體拮抗劑之苯并咪唑衍生物
|
US20200353076A1
(en)
|
2017-09-18 |
2020-11-12 |
Sutro Biopharma, Inc. |
Anti-folate receptor alpha antibody conjugates and their uses
|
CN111344293A
(zh)
|
2017-09-20 |
2020-06-26 |
阿斯利康(瑞典)有限公司 |
1,3-二氢咪唑并[4,5-c]噌啉-2-酮化合物及其在治疗癌症中的用途
|
TWI702205B
(zh)
|
2017-10-06 |
2020-08-21 |
***聯邦商拜奧卡德聯合股份公司 |
表皮生長因子受體抑制劑
|
BR112020009055A2
(pt)
|
2017-11-06 |
2020-11-03 |
Rapt Therapeutics, Inc. |
moduladores de receptor de quimiocina para tratamento de câncer positivo para vírus epstein barr
|
DK3488868T3
(da)
|
2017-11-23 |
2023-11-27 |
Medac Ges Fuer Klinische Spezialpraeparate Mbh |
Farmaceutisk sammensætning til oral indgivelse, som indeholder sulfasalazin og/eller et organisk sulfasalazinsalt, fremstillingsfremgangsmåde samt anvendelse
|
EP3489222A1
(en)
|
2017-11-23 |
2019-05-29 |
medac Gesellschaft für klinische Spezialpräparate mbH |
Sulfasalazine salts, production processes and uses
|
US11325900B2
(en)
|
2018-01-15 |
2022-05-10 |
Aucentra Holdings Pty Ltd |
5-(pyrimidin-4-yl)thiazol-2-yl urea derivatives as therapeutic agents
|
GB201801128D0
(en)
|
2018-01-24 |
2018-03-07 |
Univ Oxford Innovation Ltd |
Compounds
|
KR20200125932A
(ko)
|
2018-01-26 |
2020-11-05 |
랩트 테라퓨틱스, 인크. |
케모카인 수용체 조정제 및 그의 용도
|
JP2021512893A
(ja)
|
2018-02-08 |
2021-05-20 |
ニューファーマ,インク. |
特定の化学物質、組成物、および方法
|
CA3093189A1
(en)
|
2018-03-07 |
2019-09-12 |
Bayer Aktiengesellschaft |
Identification and use of erk5 inhibitors
|
WO2019175093A1
(en)
|
2018-03-12 |
2019-09-19 |
Astrazeneca Ab |
Method for treating lung cancer
|
WO2019197842A1
(en)
|
2018-04-13 |
2019-10-17 |
Cancer Research Technology Limited |
Bcl6 inhibitors
|
CA3098562A1
(en)
|
2018-04-27 |
2019-10-31 |
Spruce Biosciences, Inc. |
Methods for treating testicular and ovarian adrenal rest tumors
|
GB201809102D0
(en)
|
2018-06-04 |
2018-07-18 |
Univ Oxford Innovation Ltd |
Compounds
|
JP7351859B2
(ja)
|
2018-06-04 |
2023-09-27 |
アプロス セラピューティクス, インコーポレイテッド |
Tlr7の調節に関係する疾患を処置するのに有用な酸性基を含むピリミジン化合物
|
EP3802544A1
(en)
|
2018-06-05 |
2021-04-14 |
RAPT Therapeutics, Inc. |
Pyrazolo-pyrimidin-amino-cycloalkyl compounds and their therapeutic uses
|
GB201810092D0
(en)
|
2018-06-20 |
2018-08-08 |
Ctxt Pty Ltd |
Compounds
|
GB201810581D0
(en)
|
2018-06-28 |
2018-08-15 |
Ctxt Pty Ltd |
Compounds
|
US20220047716A1
(en)
|
2018-09-17 |
2022-02-17 |
Sutro Biopharma, Inc. |
Combination therapies with anti-folate receptor antibody conjugates
|
WO2020068600A1
(en)
|
2018-09-24 |
2020-04-02 |
Rapt Therapeutics, Inc. |
Ubiquitin-specific-processing protease 7 (usp7) modulators and uses thereof
|
BR112021007435A2
(pt)
|
2018-10-25 |
2021-08-03 |
Merck Patent Gmbh |
derivados de 5-azaindazol como antagonistas de receptor de adenosina
|
CA3117512A1
(en)
|
2018-10-25 |
2020-04-30 |
Merck Patent Gmbh |
5-azaindazole derivatives as adenosine receptor antagonists
|
GB201819126D0
(en)
|
2018-11-23 |
2019-01-09 |
Cancer Research Tech Ltd |
Inhibitor compounds
|
CN114729354A
(zh)
|
2018-12-25 |
2022-07-08 |
中国医学科学院基础医学研究所 |
炎性相关疾病防治的小rna药物及其组合
|
KR102334943B1
(ko)
*
|
2018-12-28 |
2021-12-06 |
한국화학연구원 |
신규 이소퀴놀린 유도체, 이의 제조방법, 및 이를 유효성분으로 함유하는 오토파지 관련 질환의 예방 또는 치료용 약학적 조성물
|
AR117844A1
(es)
|
2019-01-22 |
2021-09-01 |
Merck Patent Gmbh |
Derivados de tiazolopiridina como antagonistas del receptor de adenosina
|
AU2020232026A1
(en)
|
2019-03-07 |
2021-09-02 |
Merck Patent Gmbh |
Carboxamide-pyrimidine derivatives as shp2 antagonists
|
CN111747931A
(zh)
|
2019-03-29 |
2020-10-09 |
深圳福沃药业有限公司 |
用于治疗癌症的氮杂芳环酰胺衍生物
|
CN113905787A
(zh)
|
2019-04-05 |
2022-01-07 |
斯托姆治疗有限公司 |
Mettl3抑制化合物
|
JP2022527013A
(ja)
|
2019-04-08 |
2022-05-27 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Shp2拮抗薬としてのピリミジノン誘導体
|
GB201905328D0
(en)
|
2019-04-15 |
2019-05-29 |
Azeria Therapeutics Ltd |
Inhibitor compounds
|
EP3962951A1
(en)
|
2019-05-03 |
2022-03-09 |
Sutro Biopharma, Inc. |
Anti-bcma antibody conjugates
|
CN114096524A
(zh)
|
2019-05-15 |
2022-02-25 |
阿龙拜欧有限公司 |
用于治疗癌症、抑制趋化因子活性和/或诱导细胞死亡的小分子
|
GB201908885D0
(en)
|
2019-06-20 |
2019-08-07 |
Storm Therapeutics Ltd |
Therapeutic compounds
|
EP4023639A1
(en)
|
2019-08-31 |
2022-07-06 |
Etern Biopharma (Shanghai) Co., Ltd. |
Pyrazole derivative for fgfr inhibitor and preparation method therefor
|
BR112022004624A2
(pt)
|
2019-09-20 |
2022-05-31 |
Ideaya Biosciences Inc |
Derivados de indol e indazol sulfonamido 4-substituído como inibidores de parg
|
GB201913988D0
(en)
|
2019-09-27 |
2019-11-13 |
Celleron Therapeutics Ltd |
Novel treatment
|
GB201914860D0
(en)
|
2019-10-14 |
2019-11-27 |
Cancer Research Tech Ltd |
Inhibitor compounds
|
GB201915828D0
(en)
|
2019-10-31 |
2019-12-18 |
Cancer Research Tech Ltd |
Compounds, compositions and therapeutic uses thereof
|
GB201915829D0
(en)
|
2019-10-31 |
2019-12-18 |
Cancer Research Tech Ltd |
Compounds, compositions and therapeutic uses thereof
|
GB201915831D0
(en)
|
2019-10-31 |
2019-12-18 |
Cancer Research Tech Ltd |
Compounds, compositions and therapeutic uses thereof
|
IL293340A
(en)
|
2019-12-02 |
2022-07-01 |
Storm Therapeutics Ltd |
Polyheterocyclic compounds as mettl3 inhibitors
|
EP4114852A1
(en)
|
2020-03-03 |
2023-01-11 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific glutamine tags, methods of their preparation and methods of their use
|
GB202004960D0
(en)
|
2020-04-03 |
2020-05-20 |
Kinsenus Ltd |
Inhibitor compounds
|
GB202012969D0
(en)
|
2020-08-19 |
2020-09-30 |
Univ Of Oxford |
Inhibitor compounds
|
WO2022074379A1
(en)
|
2020-10-06 |
2022-04-14 |
Storm Therapeutics Limited |
Mettl3 inhibitory compounds
|
WO2022074391A1
(en)
|
2020-10-08 |
2022-04-14 |
Storm Therapeutics Limited |
Compounds inhibitors of mettl3
|
EP3992191A1
(en)
|
2020-11-03 |
2022-05-04 |
Deutsches Krebsforschungszentrum |
Imidazo[4,5-c]quinoline compounds and their use as atm kinase inhibitors
|
CN114948964B
(zh)
*
|
2021-02-25 |
2023-10-03 |
石药集团中奇制药技术(石家庄)有限公司 |
多靶点蛋白激酶抑制剂的用途
|
GB202102895D0
(en)
|
2021-03-01 |
2021-04-14 |
Cambridge Entpr Ltd |
Novel compounds, compositions and therapeutic uses thereof
|
WO2022197641A1
(en)
|
2021-03-15 |
2022-09-22 |
Rapt Therapeutics, Inc. |
1h-pyrazolo[3,4-d]pyrimidin-6-yl-amine derivatives as hematopoietic progenitor kinase 1 (hpk1) modulators and/or inhibitors for the treatment of cancer and other diseases
|
US11931420B2
(en)
|
2021-04-30 |
2024-03-19 |
Celgene Corporation |
Combination therapies using an anti-BCMA antibody drug conjugate (ADC) in combination with a gamma secretase inhibitor (GSI)
|
WO2022233718A2
(en)
|
2021-05-03 |
2022-11-10 |
Merck Patent Gmbh |
Her2 targeting fc antigen binding fragment-drug conjugates
|
EP4342882A1
(en)
|
2021-05-17 |
2024-03-27 |
HK inno.N Corporation |
Benzamide derivative, method for preparing same, and pharmaceutical composition for prevention or treatment of cancer containing same as active ingredient
|
IL308818A
(en)
|
2021-05-25 |
2024-01-01 |
Merck Patent Gmbh |
FC antigen-binding conjugate drug fragments targeting EGFR
|
GB202107907D0
(en)
|
2021-06-02 |
2021-07-14 |
Storm Therapeutics Ltd |
Combination therapies
|
GB202108383D0
(en)
|
2021-06-11 |
2021-07-28 |
Argonaut Therapeutics Ltd |
Compounds useful in the treatment or prevention of a prmt5-mediated disorder
|
US11878013B2
(en)
|
2021-07-02 |
2024-01-23 |
Korea Research Institute Of Chemical Technology |
Isoquinoline derivative, preparing method thereof, and pharmaceutical composition for preventing or treating autophagy related diseases containing the same as an active ingredient
|
WO2023057394A1
(en)
|
2021-10-04 |
2023-04-13 |
Forx Therapeutics Ag |
N,n-dimethyl-4-(7-(n-(1-methylcyclopropyl)sulfamoyl)-imidazo[1,5-a]pyridin-5-yl)piperazine-1-carboxamide derivatives and the corresponding pyrazolo[1,5-a]pyridine derivatives as parg inhibitors for the treatment of cancer
|
WO2023057389A1
(en)
|
2021-10-04 |
2023-04-13 |
Forx Therapeutics Ag |
Parg inhibitory compounds
|
WO2023131690A1
(en)
|
2022-01-10 |
2023-07-13 |
Merck Patent Gmbh |
Substituted heterocycles as hset inhibitors
|
GB202202199D0
(en)
|
2022-02-18 |
2022-04-06 |
Cancer Research Tech Ltd |
Compounds
|
WO2023175184A1
(en)
|
2022-03-17 |
2023-09-21 |
Forx Therapeutics Ag |
2,4-dioxo-1,4-dihydroquinazoline derivatives as parg inhibitors for the treatment of cancer
|
WO2023175185A1
(en)
|
2022-03-17 |
2023-09-21 |
Forx Therapeutics Ag |
2,4-dioxo-1,4-dihydroquinazoline derivatives as parg inhibitors for the treatment of cancer
|
WO2023186881A1
(en)
|
2022-03-29 |
2023-10-05 |
Baden-Württemberg Stiftung Ggmbh |
P38 map kinase inhibitors for use in the treatment of colorectal cancer
|
GB202204935D0
(en)
|
2022-04-04 |
2022-05-18 |
Cambridge Entpr Ltd |
Nanoparticles
|
WO2023196432A1
(en)
|
2022-04-06 |
2023-10-12 |
Rapt Therapeutics, Inc. |
Chemokine receptor modulators and uses thereof
|
GB202209404D0
(en)
|
2022-06-27 |
2022-08-10 |
Univ Of Sussex |
Compounds
|
US20240058465A1
(en)
|
2022-06-30 |
2024-02-22 |
Sutro Biopharma, Inc. |
Anti-ror1 antibody conjugates, compositions comprising anti ror1 antibody conjugates, and methods of making and using anti-ror1 antibody conjugates
|
WO2024030825A1
(en)
|
2022-08-01 |
2024-02-08 |
Neupharma, Inc |
Crystalline salts of crystalline salts of (3s,5r,8r,9s,10s,13r,14s,17r)-14-hydroxy-10,13-dimethyl-17-(2- oxo-2h-pyran-5-yl)hexadecahydro-1h-cyclopenta[a]phenanthren-3-yl piperazine-1-carboxylate
|
GB202213163D0
(en)
|
2022-09-08 |
2022-10-26 |
Cambridge Entpr Ltd |
Novel compounds, compositions and therapeutic uses thereof
|
GB202213162D0
(en)
|
2022-09-08 |
2022-10-26 |
Cambridge Entpr Ltd |
Prodrugs
|
GB202213166D0
(en)
|
2022-09-08 |
2022-10-26 |
Cambridge Entpr Ltd |
Novel compounds, compositions and therapeutic uses thereof
|
GB202213167D0
(en)
|
2022-09-08 |
2022-10-26 |
Cambridge Entpr Ltd |
Novel compounds, compositions and therapeutic uses thereof
|
GB202213164D0
(en)
|
2022-09-08 |
2022-10-26 |
Cambridge Entpr Ltd |
Novel compounds, compositions and therapeutic uses thereof
|
WO2024074497A1
(en)
|
2022-10-03 |
2024-04-11 |
Forx Therapeutics Ag |
Parg inhibitory compound
|
CN115650827B
(zh)
*
|
2022-10-27 |
2024-03-15 |
戊言医药科技(上海)有限公司 |
用于一类蒽环类毒素衍生物的制备方法、中间体化合物及合成方法
|