SE9903544D0 - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- SE9903544D0 SE9903544D0 SE9903544A SE9903544A SE9903544D0 SE 9903544 D0 SE9903544 D0 SE 9903544D0 SE 9903544 A SE9903544 A SE 9903544A SE 9903544 A SE9903544 A SE 9903544A SE 9903544 D0 SE9903544 D0 SE 9903544D0
- Authority
- SE
- Sweden
- Prior art keywords
- novel compounds
- solvate
- chem
- therapy
- processes
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Priority Applications (36)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9903544A SE9903544D0 (sv) | 1999-10-01 | 1999-10-01 | Novel compounds |
NZ517880A NZ517880A (en) | 1999-10-01 | 2000-09-26 | Novel thiazolo(4,5-D)pyrimidine compounds |
CNB008163189A CN1210279C (zh) | 1999-10-01 | 2000-09-26 | 新的噻唑并(4,5-d)嘧啶化合物 |
EP03015019A EP1348709B1 (en) | 1999-10-01 | 2000-09-26 | Thiazolo[4,5-d]pyrimidine compounds for the treatment of rheumatoid arthritis |
PL365778A PL203572B1 (pl) | 1999-10-01 | 2000-09-26 | Zwi azek tiazolo[4,5-d]pirymidynowy, sposób jego wytwarzania, zwi azki po srednie, srodek farmaceutyczny oraz zastosowanie tego zwi azku |
ES03015019T ES2298451T3 (es) | 1999-10-01 | 2000-09-26 | Compuestos de tiazolo (4,5-d)pirimidina para el tratamiento de la artritis reumatoide. |
IL14891000A IL148910A0 (en) | 1999-10-01 | 2000-09-26 | Novel thiazolo (4,5-d) pyrimidine compounds |
SI200030314T SI1222195T1 (en) | 1999-10-01 | 2000-09-26 | Novel thiazolo(4,5-d)pyrimidine compounds |
JP2001528186A JP4824889B2 (ja) | 1999-10-01 | 2000-09-26 | 新規チアゾロ(4,5−d)ピリミジン化合物 |
BR0014334-0A BR0014334A (pt) | 1999-10-01 | 2000-09-26 | Novos compostos de tiazolo (4,5-d) pirimidina |
US10/089,571 US6790850B1 (en) | 1999-10-01 | 2000-09-26 | Thiazolo(4,5-d)pyrimidine compounds |
DE60037836T DE60037836T2 (de) | 1999-10-01 | 2000-09-26 | ThiazoloÄ4,5-dÜpyrimidinverbindungen zur Behandlung von rheumathoider Arthritis |
DE60007768T DE60007768T2 (de) | 1999-10-01 | 2000-09-26 | Neue thiazolo(4,5-d)pyrimidinverbindungen |
EEP200200174A EE05037B1 (et) | 1999-10-01 | 2000-09-26 | Tiasolo( 4,5-d) primidiinihendid, meetod nende valmistamiseks ning neid sisaldav ravimkoostis |
CZ20021113A CZ20021113A3 (cs) | 1999-10-01 | 2000-09-26 | Deriváty thiazolo [4,5-d]pyrimidinu, způsob jejich přípravy a farmaceutický prostředek, který je obsahuje |
MXPA02003263A MXPA02003263A (es) | 1999-10-01 | 2000-09-26 | Compuestos novedosos de tiazol(4,5-d)pirimidina. |
UA2002032035A UA73521C2 (en) | 1999-10-01 | 2000-09-26 | Thiazolo[4,5-d]pyrimidine derivatives, a method for the preparation thereof (variants), intermediary compounds, pharmaceutical composition based thereon and a method for the preparation of such composition |
KR1020027004180A KR100765051B1 (ko) | 1999-10-01 | 2000-09-26 | 신규 티아졸로(4,5-d)피리미딘 화합물 |
EP00960891A EP1222195B1 (en) | 1999-10-01 | 2000-09-26 | Novel thiazolo(4,5-d)pyrimidine compounds |
AU73049/00A AU777872B2 (en) | 1999-10-01 | 2000-09-26 | Novel thiazolo(4,5-D)pyrimidine compounds |
DK00960891T DK1222195T3 (da) | 1999-10-01 | 2000-09-26 | Hidtil ukendte thiazolo[4,5-d]pyrimidinforbindelser |
PCT/GB2000/003692 WO2001025242A1 (en) | 1999-10-01 | 2000-09-26 | Novel thiazolo(4,5-d)pyrimidine compounds |
CA2385269A CA2385269C (en) | 1999-10-01 | 2000-09-26 | Novel thiazolo(4,5-d)pyrimidine compounds |
ES00960891T ES2213043T3 (es) | 1999-10-01 | 2000-09-26 | Nuevos compuestos de tiazolo(4,5-d)pirimidina. |
AT00960891T ATE257838T1 (de) | 1999-10-01 | 2000-09-26 | Neue thiazolo(4,5-d)pyrimidinverbindungen |
AT03015019T ATE384068T1 (de) | 1999-10-01 | 2000-09-26 | Thiazolo(4,5-d)pyrimidinverbindungen zur behandlung von rheumathoider arthritis |
PT00960891T PT1222195E (pt) | 1999-10-01 | 2000-09-26 | Novos compostos de tiazolo(4,5-d)pirimidina |
HU0204246A HUP0204246A3 (en) | 1999-10-01 | 2000-09-26 | Novel thiazolo[4,5-d]pyrimidine compounds, process for their preparation, pharmaceutical compositions containing them and their use |
TW089121952A TWI260324B (en) | 1999-10-01 | 2000-10-19 | Thiazolopyrimidinone compounds, process for preparing the same, and pharmaceutical composition comprising the same |
IS6306A IS2229B (is) | 1999-10-01 | 2002-03-18 | Ný þíasóló(4,5-d)pýrimídínefnasambönd |
NO20021448A NO327706B1 (no) | 1999-10-01 | 2002-03-22 | Nye tiazolo-(4,5-D)pyrimidinforbindelser, fremgangsmate for fremstilling derav, farmasoytisk preparat og mellomprodukter |
ZA200202380A ZA200202380B (en) | 1999-10-01 | 2002-03-25 | Novel thiazolo(4,5-D)pyrimidine compounds. |
IL148910A IL148910A (en) | 1999-10-01 | 2002-03-26 | 7 - Amino - Thiazole (D – 5,4) Pyrimidine - 2 - (N3) - Converted lobes in position 5, their preparation, pharmaceutical preparations containing them and a number of their intermediates |
HK03104330A HK1052009A1 (en) | 1999-10-01 | 2003-06-17 | Novel thiazolo (4,5-D) pyrimidine compounds |
US10/863,995 US20040224961A1 (en) | 1999-10-01 | 2004-06-09 | Novel thiazolo (4,5-D) pyrimidine compounds |
US12/432,224 US8143261B2 (en) | 1999-10-01 | 2009-04-29 | Thiazolo (4,5-D) pyrimidine compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9903544A SE9903544D0 (sv) | 1999-10-01 | 1999-10-01 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9903544D0 true SE9903544D0 (sv) | 1999-10-01 |
Family
ID=20417218
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9903544A SE9903544D0 (sv) | 1999-10-01 | 1999-10-01 | Novel compounds |
Country Status (27)
Country | Link |
---|---|
US (3) | US6790850B1 (sv) |
EP (2) | EP1222195B1 (sv) |
JP (1) | JP4824889B2 (sv) |
KR (1) | KR100765051B1 (sv) |
CN (1) | CN1210279C (sv) |
AT (2) | ATE384068T1 (sv) |
AU (1) | AU777872B2 (sv) |
BR (1) | BR0014334A (sv) |
CA (1) | CA2385269C (sv) |
CZ (1) | CZ20021113A3 (sv) |
DE (2) | DE60007768T2 (sv) |
DK (1) | DK1222195T3 (sv) |
EE (1) | EE05037B1 (sv) |
ES (2) | ES2298451T3 (sv) |
HK (1) | HK1052009A1 (sv) |
HU (1) | HUP0204246A3 (sv) |
IL (2) | IL148910A0 (sv) |
IS (1) | IS2229B (sv) |
MX (1) | MXPA02003263A (sv) |
NO (1) | NO327706B1 (sv) |
NZ (1) | NZ517880A (sv) |
PT (1) | PT1222195E (sv) |
SE (1) | SE9903544D0 (sv) |
TW (1) | TWI260324B (sv) |
UA (1) | UA73521C2 (sv) |
WO (1) | WO2001025242A1 (sv) |
ZA (1) | ZA200202380B (sv) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9903544D0 (sv) * | 1999-10-01 | 1999-10-01 | Astra Pharma Prod | Novel compounds |
GB2359081A (en) * | 2000-02-11 | 2001-08-15 | Astrazeneca Uk Ltd | Pharmaceutically active thiazolopyrimidines |
GB2359078A (en) | 2000-02-11 | 2001-08-15 | Astrazeneca Uk Ltd | Pharmaceutically active pyrimidine derivatives |
EP1257555B1 (en) * | 2000-02-11 | 2003-12-03 | AstraZeneca AB | Pyrimidine compounds and their use as modulators of chemokine receptor activity |
GB2359551A (en) * | 2000-02-23 | 2001-08-29 | Astrazeneca Uk Ltd | Pharmaceutically active pyrimidine derivatives |
SE0003828D0 (sv) | 2000-10-20 | 2000-10-20 | Astrazeneca Ab | Novel compounds |
SE0101322D0 (sv) | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | Novel compounds |
SE0102716D0 (sv) * | 2001-08-14 | 2001-08-14 | Astrazeneca Ab | Novel compounds |
DE60234278D1 (de) | 2001-12-06 | 2009-12-17 | Merck & Co Inc | Mitotische kinesin-hemmer |
AU2002363960B2 (en) | 2001-12-06 | 2008-07-10 | Merck Sharp & Dohme Corp. | Mitotic kinesin inhibitors |
GB0217431D0 (en) * | 2002-07-27 | 2002-09-04 | Astrazeneca Ab | Novel compounds |
CA2494421A1 (en) | 2002-08-06 | 2004-02-12 | Astrazeneca Ab | Condensed pyridines and pyrimidines with tie2 (tek) activity |
WO2004018435A1 (en) | 2002-08-24 | 2004-03-04 | Astrazeneca Ab | Pyrimidine derivatives as modulators of chemokine receptor activity |
GB0221828D0 (en) * | 2002-09-20 | 2002-10-30 | Astrazeneca Ab | Novel compound |
GB0221829D0 (en) * | 2002-09-20 | 2002-10-30 | Astrazeneca Ab | Novel compound |
US20070142386A1 (en) * | 2003-10-07 | 2007-06-21 | Astrazeneca | New 2-substituted, 4-amino-thiazolo[4,5-d] pyrimidines, useful as chemokine receptor antagonists, esp. cx3cr1 |
GB0328243D0 (en) * | 2003-12-05 | 2004-01-07 | Astrazeneca Ab | Methods |
RU2408587C2 (ru) | 2004-08-24 | 2011-01-10 | Астразенека Аб | Производные пиримидинсульфонамида в качестве модуляторов рецепторов хемокинов |
WO2006064228A2 (en) * | 2004-12-17 | 2006-06-22 | Astrazeneca Ab | Thiazolopyramidine compounds for the modulation of chemokine receptor activity |
US20090305321A1 (en) * | 2005-03-23 | 2009-12-10 | Astrazeneca Ab | Assays for Allosteric Modulators of G-Protein Coupled Receptors (GPCRs) |
AR053347A1 (es) | 2005-04-06 | 2007-05-02 | Astrazeneca Ab | Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos |
UA90707C2 (en) * | 2005-04-06 | 2010-05-25 | Астразенека Аб | Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives |
TW200820973A (en) | 2006-09-29 | 2008-05-16 | Astrazeneca Ab | Novel compounds 480 |
AR071036A1 (es) * | 2008-03-26 | 2010-05-19 | Astrazeneca Ab | Derivados 5, 7-disustituidos de [1, 3]tiazolo[4, 5-d]pirimidin-2 (3h)-ona, una composicion farmaceutica que los comprende y su uso en el tratamiento de enfermedades mediadas por el receptor cx3cr1. |
CN101671336B (zh) | 2009-09-23 | 2013-11-13 | 辽宁利锋科技开发有限公司 | 芳杂环并嘧啶衍生物和类似物及其制备方法和用途 |
CN101899058B (zh) * | 2010-05-24 | 2012-05-23 | 中国人民解放军第四军医大学 | 一种噻唑并嘧啶化合物及其制备方法和应用 |
EP3011012B1 (en) | 2013-06-18 | 2018-09-12 | New York University | Cellular factors involved in the cytotoxicity of staphylococcus aureus leukocidins: novel therapeutic targets |
US10046002B2 (en) | 2013-08-02 | 2018-08-14 | Syntrix Biosystems Inc. | Method for treating cancer using chemokine antagonists |
CN110200979A (zh) * | 2013-08-02 | 2019-09-06 | Syntrix生物***公司 | 一种硼酸化合物 |
US10561676B2 (en) | 2013-08-02 | 2020-02-18 | Syntrix Biosystems Inc. | Method for treating cancer using dual antagonists of CXCR1 and CXCR2 |
US8969365B2 (en) | 2013-08-02 | 2015-03-03 | Syntrix Biosystems, Inc. | Thiopyrimidinecarboxamides as CXCR1/2 modulators |
WO2018073248A1 (en) | 2016-10-17 | 2018-04-26 | Icm (Institut Du Cerveau Et De La Moelle Épinière) | Prognosis of demyelinating diseases patients and treatment thereof |
CN110172067B (zh) * | 2019-04-11 | 2021-06-15 | 河南科技大学第一附属医院 | 一种具有杀菌活性的噻唑类药物分子及其制备方法 |
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SE9802729D0 (sv) | 1998-08-13 | 1998-08-13 | Astra Pharma Prod | Novel Compounds |
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1999
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2000
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