CN114729354A - 炎性相关疾病防治的小rna药物及其组合 - Google Patents
炎性相关疾病防治的小rna药物及其组合 Download PDFInfo
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- CN114729354A CN114729354A CN201880100050.3A CN201880100050A CN114729354A CN 114729354 A CN114729354 A CN 114729354A CN 201880100050 A CN201880100050 A CN 201880100050A CN 114729354 A CN114729354 A CN 114729354A
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Abstract
提供了小RNA、包含小RNA的组合物以及其使用方法和用途。所述小RNA或组合物可以抑制表3中列出的任一种或多种通路或基因的能力或在体内或体外降低或下调IL‑1beta、IL‑6或/和TNF‑alpha的表达水平或治疗或预防受试者中IL‑1beta、IL‑6或/和TNF‑alpha相关疾病和/或提高细胞生存率。
Description
PCT国内申请,说明书已公开。
Claims (25)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (1)
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PCT/CN2018/123289 WO2020132844A1 (zh) | 2018-12-25 | 2018-12-25 | 炎性相关疾病防治的小rna药物及其组合 |
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CN114729354A true CN114729354A (zh) | 2022-07-08 |
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US (1) | US20230272402A1 (zh) |
EP (1) | EP3960858A4 (zh) |
CN (1) | CN114729354A (zh) |
CA (1) | CA3124730A1 (zh) |
WO (1) | WO2020132844A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN115350187A (zh) * | 2022-08-30 | 2022-11-18 | 中山大学 | 异丙托溴铵在抑制肺癌骨转移中的应用 |
Families Citing this family (2)
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WO2023143480A1 (zh) * | 2022-01-28 | 2023-08-03 | 中国医学科学院基础医学研究所 | 抑制癌细胞活性的小rna药物 |
CN114645050B (zh) * | 2022-05-07 | 2024-02-23 | 贵州大学 | 一种miRNA及其在制备治疗乳腺癌的药物中的应用 |
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- 2018-12-25 WO PCT/CN2018/123289 patent/WO2020132844A1/zh unknown
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CN115350187A (zh) * | 2022-08-30 | 2022-11-18 | 中山大学 | 异丙托溴铵在抑制肺癌骨转移中的应用 |
CN115350187B (zh) * | 2022-08-30 | 2023-08-29 | 中山大学 | 异丙托溴铵在抑制肺癌骨转移中的应用 |
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EP3960858A1 (en) | 2022-03-02 |
WO2020132844A1 (zh) | 2020-07-02 |
CA3124730A1 (en) | 2020-07-02 |
EP3960858A4 (en) | 2023-02-15 |
US20230272402A1 (en) | 2023-08-31 |
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