ATE368665T1 - Oxindolylchinazolinderivate als angiogenesehemmer - Google Patents
Oxindolylchinazolinderivate als angiogenesehemmerInfo
- Publication number
- ATE368665T1 ATE368665T1 AT98939756T AT98939756T ATE368665T1 AT E368665 T1 ATE368665 T1 AT E368665T1 AT 98939756 T AT98939756 T AT 98939756T AT 98939756 T AT98939756 T AT 98939756T AT E368665 T1 ATE368665 T1 AT E368665T1
- Authority
- AT
- Austria
- Prior art keywords
- angiogenesis inhibitors
- salts
- compounds
- oxindolylquinazoline
- derivatives
- Prior art date
Links
- 229940121369 angiogenesis inhibitor Drugs 0.000 title 1
- 239000004037 angiogenesis inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 abstract 1
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97401974 | 1997-08-22 | ||
EP97401972 | 1997-08-22 | ||
EP97401973 | 1997-08-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE368665T1 true ATE368665T1 (de) | 2007-08-15 |
Family
ID=27238731
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98939756T ATE368665T1 (de) | 1997-08-22 | 1998-08-19 | Oxindolylchinazolinderivate als angiogenesehemmer |
Country Status (8)
Country | Link |
---|---|
US (1) | US6294532B1 (de) |
EP (1) | EP1005470B1 (de) |
JP (2) | JP4959049B2 (de) |
AT (1) | ATE368665T1 (de) |
AU (1) | AU8816298A (de) |
DE (1) | DE69838172T2 (de) |
ES (1) | ES2289791T3 (de) |
WO (1) | WO1999010349A1 (de) |
Families Citing this family (132)
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- 1998-08-19 WO PCT/GB1998/002493 patent/WO1999010349A1/en active IP Right Grant
- 1998-08-19 AT AT98939756T patent/ATE368665T1/de not_active IP Right Cessation
- 1998-08-19 JP JP2000507677A patent/JP4959049B2/ja not_active Expired - Fee Related
- 1998-08-19 ES ES98939756T patent/ES2289791T3/es not_active Expired - Lifetime
- 1998-08-19 US US09/486,051 patent/US6294532B1/en not_active Expired - Fee Related
- 1998-08-19 DE DE69838172T patent/DE69838172T2/de not_active Expired - Lifetime
- 1998-08-19 EP EP98939756A patent/EP1005470B1/de not_active Expired - Lifetime
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2009
- 2009-09-24 JP JP2009219619A patent/JP2010043091A/ja active Pending
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JP4959049B2 (ja) | 2012-06-20 |
JP2010043091A (ja) | 2010-02-25 |
JP2001514182A (ja) | 2001-09-11 |
EP1005470B1 (de) | 2007-08-01 |
AU8816298A (en) | 1999-03-16 |
EP1005470A1 (de) | 2000-06-07 |
DE69838172D1 (de) | 2007-09-13 |
DE69838172T2 (de) | 2008-04-10 |
ES2289791T3 (es) | 2008-02-01 |
WO1999010349A1 (en) | 1999-03-04 |
US6294532B1 (en) | 2001-09-25 |
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