RU2022100434A - Фармацевтические композиции, содержащие epa и сердечно-сосудистое средство, и способы их применения - Google Patents

Фармацевтические композиции, содержащие epa и сердечно-сосудистое средство, и способы их применения Download PDF

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RU2022100434A
RU2022100434A RU2022100434A RU2022100434A RU2022100434A RU 2022100434 A RU2022100434 A RU 2022100434A RU 2022100434 A RU2022100434 A RU 2022100434A RU 2022100434 A RU2022100434 A RU 2022100434A RU 2022100434 A RU2022100434 A RU 2022100434A
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composition
epa
statin
methods
application
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RU2022100434A
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Мехар МАНКУ
Джонатан РОУ
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Амарин Фармасьютикалз Айрлэнд Лимитед
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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Claims (8)

1. Фармацевтическая композиция, содержащая статин, суспендированный в эйкозапентаеновой кислоте (EPA) или ее производном, при этом композиция находится в капсуле.
2. Фармацевтическая композиция по п.1, где EPA или ее производное содержат этил-EPA.
3. Композиция по п.2, где этил-EPA составляет по меньшей мере 95% по массе всех жирных кислот или их производных, присутствующих в композиции.
4. Композиция по п.3, где статин выбран из ловастатина, мевастатина, питавастатина, правастатина, розувастатина, флувастатина, аторвастатина и симвастатина.
5. Композиция по п.2, где в капсуле содержится от приблизительно 900 мг до приблизительно 1 г этил-EPA.
6. Композиция по п.4, где в капсуле содержится от приблизительно 1 мг до приблизительно 80 мг статина.
7. Композиция по п.6, где статин включает розувастатин и присутствует в капсуле в количестве от приблизительно 5 мг до приблизительно 40 мг.
8. Композиция по п.1, где статин находится в форме таблетки.
RU2022100434A 2009-04-29 2017-12-22 Фармацевтические композиции, содержащие epa и сердечно-сосудистое средство, и способы их применения RU2022100434A (ru)

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RU2013106526A RU2624506C2 (ru) 2009-04-29 2010-04-29 Фармацевтические композиции, содержащие ера и сердечно-сосудистое средство, и способы их применения
RU2011148363/15A RU2489145C1 (ru) 2009-04-29 2010-04-29 Фармацевтические композиции, содержащие ера и сердечно-сосудистое средство, и способ их применения
RU2013116807A RU2648826C2 (ru) 2009-04-29 2013-04-12 Фармацевтические композиции, содержащие ера и сердечно-сосудистое средство, и способы их применения
RU2017121277A RU2746945C2 (ru) 2009-04-29 2017-06-19 Фармацевтические композиции, содержащие epa и сердечно-сосудистое средство, и способы их применения
RU2022100434A RU2022100434A (ru) 2009-04-29 2017-12-22 Фармацевтические композиции, содержащие epa и сердечно-сосудистое средство, и способы их применения

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RU2011148363/15A RU2489145C1 (ru) 2009-04-29 2010-04-29 Фармацевтические композиции, содержащие ера и сердечно-сосудистое средство, и способ их применения
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