CU22545A1
(es)
|
1994-11-18 |
1999-03-31 |
Centro Inmunologia Molecular |
Obtención de un anticuerpo quimérico y humanizado contra el receptor del factor de crecimiento epidérmico para uso diagnóstico y terapéutico
|
GB1458148A
(en)
|
1974-04-19 |
1976-12-08 |
Wyeth John & Brother Ltd |
Carbocyclic-fused ring quinoline derivatives
|
JPS57123267A
(en)
|
1981-01-23 |
1982-07-31 |
Kansai Paint Co Ltd |
Thermosetting paint composition
|
US4526988A
(en)
|
1983-03-10 |
1985-07-02 |
Eli Lilly And Company |
Difluoro antivirals and intermediate therefor
|
EP0154434B1
(en)
|
1984-02-17 |
1993-01-27 |
Genentech, Inc. |
Human transforming growth factor and precursor or fragment thereof, cells, dna, vectors and methods for their production, compositions and products containing them, and related antibodies and diagnostic methods
|
US4582789A
(en)
|
1984-03-21 |
1986-04-15 |
Cetus Corporation |
Process for labeling nucleic acids using psoralen derivatives
|
DE8411409U1
(de)
|
1984-04-11 |
1984-08-30 |
Dr.-Ing. Walter Frohn-Betriebe, 8000 München |
Entgasungsventil fuer lager- und/oder transportbehaelter
|
US4563417A
(en)
|
1984-08-31 |
1986-01-07 |
Miles Laboratories, Inc. |
Nucleic acid hybridization assay employing antibodies to intercalation complexes
|
ATE37196T1
(de)
|
1984-11-22 |
1988-09-15 |
Holsten Brauerei Ag |
Bier und verfahren zu dessen herstellung.
|
ATE92499T1
(de)
|
1984-12-04 |
1993-08-15 |
Lilly Co Eli |
Tumorbehandlung bei saeugetieren.
|
JPS61148115A
(ja)
|
1984-12-21 |
1986-07-05 |
Tooa Eiyoo Kk |
難溶性薬物の徐放性製剤及びその製造法
|
JPS62168137A
(ja)
|
1985-12-20 |
1987-07-24 |
Fuji Photo Film Co Ltd |
ハロゲン化銀カラ−写真感光材料およびその処理方法
|
CH656535A5
(en)
|
1986-01-24 |
1986-07-15 |
Spirig Ag |
Process for the production of stable pharmaceutical tablets which disintegrate rapidly in water
|
JPH07106295B2
(ja)
|
1986-07-22 |
1995-11-15 |
エーザイ株式会社 |
調湿剤
|
US4743450A
(en)
|
1987-02-24 |
1988-05-10 |
Warner-Lambert Company |
Stabilized compositions
|
CA1339136C
(en)
|
1987-07-01 |
1997-07-29 |
Sailesh Amilal Varia |
Amorphous form of aztreonam
|
US5009894A
(en)
|
1988-03-07 |
1991-04-23 |
Baker Cummins Pharmaceuticals, Inc. |
Arrangement for and method of administering a pharmaceutical preparation
|
AU4128089A
(en)
|
1988-09-15 |
1990-03-22 |
Rorer International (Overseas) Inc. |
Monoclonal antibodies specific to human epidermal growth factor receptor and therapeutic methods employing same
|
US5143854A
(en)
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
US4983615A
(en)
|
1989-06-28 |
1991-01-08 |
Hoechst-Roussel Pharmaceuticals Inc. |
Heteroarylamino- and heteroaryloxypyridinamine compounds which are useful in treating skin disorders
|
EP0408496A3
(en)
|
1989-07-12 |
1992-07-01 |
Ciba-Geigy Ag |
Solid dosage form for pharmaceutical substances
|
US5120548A
(en)
|
1989-11-07 |
1992-06-09 |
Merck & Co., Inc. |
Swelling modulated polymeric drug delivery device
|
US5180818A
(en)
|
1990-03-21 |
1993-01-19 |
The University Of Colorado Foundation, Inc. |
Site specific cleavage of single-stranded dna
|
US5210015A
(en)
|
1990-08-06 |
1993-05-11 |
Hoffman-La Roche Inc. |
Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
|
EP0562047A4
(en)
|
1990-12-06 |
1995-11-02 |
Affymax Tech Nv |
Sequencing by hybridization of a target nucleic acid to a matrix of defined oligonucleotides
|
GB9105677D0
(en)
|
1991-03-19 |
1991-05-01 |
Ici Plc |
Heterocyclic compounds
|
US5367057A
(en)
|
1991-04-02 |
1994-11-22 |
The Trustees Of Princeton University |
Tyrosine kinase receptor flk-2 and fragments thereof
|
US5710158A
(en)
|
1991-05-10 |
1998-01-20 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
|
US5721237A
(en)
|
1991-05-10 |
1998-02-24 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of HER-2 autophosphorylation properties
|
ATE159009T1
(de)
|
1991-05-10 |
1997-10-15 |
Rhone Poulenc Rorer Int |
Bis mono- und bicyclische aryl- und heteroarylderivate mit inhibierender wirkung auf die egf und/oder pdgf-rezeptor tyrosinkinase
|
JPH04341454A
(ja)
|
1991-05-16 |
1992-11-27 |
Canon Inc |
シート収納装置
|
US5750376A
(en)
|
1991-07-08 |
1998-05-12 |
Neurospheres Holdings Ltd. |
In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
|
US5211951A
(en)
|
1991-07-24 |
1993-05-18 |
Merck & Co., Inc. |
Process for the manufacture of bioerodible poly (orthoester)s and polyacetals
|
JPH05194259A
(ja)
*
|
1991-08-30 |
1993-08-03 |
Mitsubishi Kasei Corp |
抗消化性潰瘍剤
|
US5200194A
(en)
|
1991-12-18 |
1993-04-06 |
Alza Corporation |
Oral osmotic device
|
AU678764B2
(en)
|
1992-06-03 |
1997-06-12 |
Case Western Reserve University |
Bandage for continuous application of biologicals
|
TW271400B
(es)
*
|
1992-07-30 |
1996-03-01 |
Pfizer |
|
GB9221220D0
(en)
|
1992-10-09 |
1992-11-25 |
Sandoz Ag |
Organic componds
|
JPH06153952A
(ja)
|
1992-11-26 |
1994-06-03 |
Nobuaki Tamamaki |
微量未知二重鎖dna分子の増幅、標識を行うための前処理方法
|
GB9323290D0
(en)
|
1992-12-10 |
1994-01-05 |
Zeneca Ltd |
Quinazoline derivatives
|
CA2150372C
(en)
|
1993-01-19 |
2002-08-20 |
Nancy L. Mills |
Stable oral ci-981 formulation and process of preparing same
|
US6027880A
(en)
|
1995-08-02 |
2000-02-22 |
Affymetrix, Inc. |
Arrays of nucleic acid probes and methods of using the same for detecting cystic fibrosis
|
US6156501A
(en)
|
1993-10-26 |
2000-12-05 |
Affymetrix, Inc. |
Arrays of modified nucleic acid probes and methods of use
|
JPH07176103A
(ja)
|
1993-12-20 |
1995-07-14 |
Canon Inc |
光磁気記録再生システムならびにこれに用いる磁気ヘッド及び光磁気記録媒体
|
GB9326136D0
(en)
|
1993-12-22 |
1994-02-23 |
Erba Carlo Spa |
Biologically active 3-substituted oxindole derivatives useful as anti-angiogenic agents
|
IL112249A
(en)
|
1994-01-25 |
2001-11-25 |
Warner Lambert Co |
Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
|
US6811779B2
(en)
|
1994-02-10 |
2004-11-02 |
Imclone Systems Incorporated |
Methods for reducing tumor growth with VEGF receptor antibody combined with radiation and chemotherapy
|
JP3660391B2
(ja)
|
1994-05-27 |
2005-06-15 |
株式会社東芝 |
半導体装置の製造方法
|
JPH0848078A
(ja)
|
1994-08-05 |
1996-02-20 |
Nippon Paper Ind Co Ltd |
感熱記録体
|
GB9510757D0
(en)
|
1994-09-19 |
1995-07-19 |
Wellcome Found |
Therapeuticaly active compounds
|
US5656454A
(en)
|
1994-10-04 |
1997-08-12 |
President And Fellows Of Harvard College |
Endothelial cell-specific enhancer
|
JP3207058B2
(ja)
|
1994-11-07 |
2001-09-10 |
財団法人国際超電導産業技術研究センター |
超電導体薄膜及びその製造方法
|
IL115256A0
(en)
|
1994-11-14 |
1995-12-31 |
Warner Lambert Co |
6-Aryl pyrido (2,3-d) pyrimidines and naphthyridines and their use
|
JPH08176138A
(ja)
|
1994-12-19 |
1996-07-09 |
Mercian Corp |
イソクマリン誘導体
|
US5948438A
(en)
|
1995-01-09 |
1999-09-07 |
Edward Mendell Co., Inc. |
Pharmaceutical formulations having improved disintegration and/or absorptivity
|
US5658374A
(en)
|
1995-02-28 |
1997-08-19 |
Buckman Laboratories International, Inc. |
Aqueous lecithin-based release aids and methods of using the same
|
US5624937A
(en)
|
1995-03-02 |
1997-04-29 |
Eli Lilly And Company |
Chemical compounds as inhibitors of amyloid beta protein production
|
US6579314B1
(en)
|
1995-03-10 |
2003-06-17 |
C.R. Bard, Inc. |
Covered stent with encapsulated ends
|
DE69536015D1
(de)
|
1995-03-30 |
2009-12-10 |
Pfizer Prod Inc |
Chinazolinone Derivate
|
GB9508538D0
(en)
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
DK0831829T3
(da)
|
1995-06-07 |
2003-12-15 |
Pfizer |
Heterocykliske, ringkondenserede pyrimidinderivater
|
US5880141A
(en)
|
1995-06-07 |
1999-03-09 |
Sugen, Inc. |
Benzylidene-Z-indoline compounds for the treatment of disease
|
US5654005A
(en)
|
1995-06-07 |
1997-08-05 |
Andrx Pharmaceuticals, Inc. |
Controlled release formulation having a preformed passageway
|
JPH0923885A
(ja)
|
1995-07-12 |
1997-01-28 |
Dai Ichi Seiyaku Co Ltd |
遺伝子発現ライブラリー及びその製造法
|
GB9514265D0
(en)
|
1995-07-13 |
1995-09-13 |
Wellcome Found |
Hetrocyclic compounds
|
GB9520822D0
(en)
|
1995-10-11 |
1995-12-13 |
Wellcome Found |
Therapeutically active compounds
|
AR004010A1
(es)
|
1995-10-11 |
1998-09-30 |
Glaxo Group Ltd |
Compuestos heterociclicos
|
US6346398B1
(en)
|
1995-10-26 |
2002-02-12 |
Ribozyme Pharmaceuticals, Inc. |
Method and reagent for the treatment of diseases or conditions related to levels of vascular endothelial growth factor receptor
|
US6143764A
(en)
|
1995-11-07 |
2000-11-07 |
Kirin Beer Kabushiki Kaisha |
Quinoline and quinazoline derivatives inhibiting platelet-derived growth factor receptor autophosphorylation and pharmaceutical compositions containing the same
|
US5849759A
(en)
|
1995-12-08 |
1998-12-15 |
Berlex Laboratories, Inc. |
Naphthyl-substituted benzimidazole derivatives as anti-coagulants
|
GB9604361D0
(en)
|
1996-02-29 |
1996-05-01 |
Pharmacia Spa |
4-Substituted pyrrolopyrimidine compounds as tyrosine kinase inhibitors
|
JPH09234074A
(ja)
|
1996-03-04 |
1997-09-09 |
Sumitomo Electric Ind Ltd |
アダプター二本鎖dna及びそれを用いたdna増幅方法
|
AU2733997A
(en)
|
1996-04-17 |
1997-11-07 |
Du Pont Pharmaceuticals Company |
N-(amidinophenyl)-n'-(subst.)-3h-2,4-benzodiazepin-3-one derivatives as factor xa inhibitors
|
WO1997046313A1
(en)
|
1996-06-07 |
1997-12-11 |
Eos Biotechnology, Inc. |
Immobilised linear oligonucleotide arrays
|
AU721130B2
(en)
|
1996-06-28 |
2000-06-22 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
ATE227283T1
(de)
|
1996-07-13 |
2002-11-15 |
Glaxo Group Ltd |
Kondensierte heterozyklische verbindungen als protein kinase inhibitoren
|
HRP970371A2
(en)
|
1996-07-13 |
1998-08-31 |
Kathryn Jane Smith |
Heterocyclic compounds
|
AU3693697A
(en)
|
1996-07-13 |
1998-02-09 |
Glaxo Group Limited |
Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors
|
JPH10147524A
(ja)
|
1996-09-20 |
1998-06-02 |
Nippon Kayaku Co Ltd |
フォルスコリン誘導体含有経口製剤及び医薬製剤の製法
|
CA2263479A1
(en)
|
1996-09-25 |
1998-04-02 |
Zeneca Limited |
Quinoline derivatives inhibiting the effect of growth factors such as vegf
|
EP0930305B1
(en)
|
1996-09-30 |
2003-05-14 |
Nihon Nohyaku Co., Ltd. |
1,2,3-thiadiazole derivatives and salts thereof, disease controlling agents for agricultural and horticultural use, and method for the use thereof
|
JPH10114655A
(ja)
|
1996-10-09 |
1998-05-06 |
Kyowa Hakko Kogyo Co Ltd |
固形製剤
|
EP0837063A1
(en)
|
1996-10-17 |
1998-04-22 |
Pfizer Inc. |
4-Aminoquinazoline derivatives
|
WO1998023613A1
(en)
|
1996-11-27 |
1998-06-04 |
Pfizer Inc. |
Fused bicyclic pyrimidine derivatives
|
TW486370B
(en)
|
1996-12-25 |
2002-05-11 |
Yamanouchi Pharma Co Ltd |
Rapidly disintegrable pharmaceutical composition
|
CA2275777A1
(en)
|
1997-01-29 |
1998-07-30 |
Louise Richman Levine |
Treatment for premenstrual dysphoric disorder
|
CO4950519A1
(es)
|
1997-02-13 |
2000-09-01 |
Novartis Ag |
Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
|
JP3040486U
(ja)
|
1997-02-13 |
1997-08-19 |
有限会社ザップ |
フィッシングジャケット
|
DK0968206T3
(da)
|
1997-02-19 |
2007-03-26 |
Berlex Inc |
N-heterocykliske derivater som NOS-inhibitorer
|
US6090556A
(en)
|
1997-04-07 |
2000-07-18 |
Japan Science & Technology Corporation |
Method for quantitatively determining the expression of a gene
|
WO1998050346A2
(en)
|
1997-04-18 |
1998-11-12 |
Smithkline Beecham Plc |
Acetamide and urea derivatives, process for their preparation and their use in the treatment of cns disorders
|
JPH10316576A
(ja)
|
1997-05-13 |
1998-12-02 |
Nissui Pharm Co Ltd |
キトサン含有錠剤
|
DE1019040T1
(de)
|
1997-05-23 |
2001-02-08 |
Bayer Ag |
Hemmung von p38 kinase aktivität durch arylharnstoff
|
WO1998056787A1
(en)
|
1997-06-10 |
1998-12-17 |
Synthon B.V. |
4-Phenylpiperidine compounds
|
US6093742A
(en)
|
1997-06-27 |
2000-07-25 |
Vertex Pharmaceuticals, Inc. |
Inhibitors of p38
|
WO1999001738A2
(en)
|
1997-06-30 |
1999-01-14 |
University Of Maryland, Baltimore |
Heparin binding-epidermal growth factor in the diagnosis of interstitial cystitis
|
BE1011251A3
(fr)
|
1997-07-03 |
1999-06-01 |
Ucb Sa |
Compositions pharmaceutiques administrables par voie orale, comprenant une substance active et une cyclodextrine.
|
CO4940418A1
(es)
|
1997-07-18 |
2000-07-24 |
Novartis Ag |
Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
|
JP3765918B2
(ja)
|
1997-11-10 |
2006-04-12 |
パイオニア株式会社 |
発光ディスプレイ及びその駆動方法
|
JP4194678B2
(ja)
|
1997-11-28 |
2008-12-10 |
キリンファーマ株式会社 |
キノリン誘導体およびそれを含む医薬組成物
|
DE69836563T2
(de)
|
1997-12-22 |
2007-05-16 |
Bayer Pharmaceuticals Corp., West Haven |
INHIBIERUNG DER p38 KINASE-AKTIVITÄT DURCH DIE VERWENDUNG VON ARYL- UND HETEROARYL-SUBSTITUIERTEN HARNSTOFFEN
|
NZ505844A
(en)
|
1997-12-22 |
2003-10-31 |
Bayer Ag |
Inhibition of raf kinase using substituted heterocyclic ureas
|
HU227711B1
(en)
|
1997-12-22 |
2011-12-28 |
Bayer Healthcare Llc |
Inhibition of raf kinase using symmetrical and unsymmetrical substituted diphenyl ureas and pharmaceutical compositions containing them
|
ATE529109T1
(de)
|
1997-12-22 |
2011-11-15 |
Bayer Healthcare Llc |
Hemmung der p38 kinase aktivität durch substituierte heterocyclische harnstoffe
|
GB9800569D0
(en)
|
1998-01-12 |
1998-03-11 |
Glaxo Group Ltd |
Heterocyclic compounds
|
GB9800575D0
(en)
|
1998-01-12 |
1998-03-11 |
Glaxo Group Ltd |
Heterocyclic compounds
|
CN1310706A
(zh)
|
1998-02-25 |
2001-08-29 |
遗传研究所有限公司 |
磷脂酶抑制剂
|
KR20010041609A
(ko)
|
1998-03-06 |
2001-05-25 |
유란드 인터내셔날 에스.피.아. |
속해성 정제
|
DE19814257A1
(de)
|
1998-03-31 |
1999-10-07 |
Asta Medica Ag |
Brauseformulierungen
|
JPH11322596A
(ja)
|
1998-05-12 |
1999-11-24 |
Shionogi & Co Ltd |
白金錯体および環状リン酸エステルアミドを含有する抗癌剤
|
UA60365C2
(uk)
|
1998-06-04 |
2003-10-15 |
Пфайзер Продактс Інк. |
Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
|
EP2277873B1
(en)
|
1998-06-17 |
2012-05-30 |
Eisai R&D Management Co., Ltd. |
Intermediate compound for the preparation of halichondrin analogs
|
US6653341B1
(en)
|
1998-06-17 |
2003-11-25 |
Eisai Co., Ltd. |
Methods and compositions for use in treating cancer
|
US8097648B2
(en)
|
1998-06-17 |
2012-01-17 |
Eisai R&D Management Co., Ltd. |
Methods and compositions for use in treating cancer
|
EP1121104B1
(en)
|
1998-10-01 |
2005-01-12 |
Novartis AG |
New controlled release oral formulations for rivastigmine
|
WO2000031048A1
(en)
|
1998-11-19 |
2000-06-02 |
Warner-Lambert Company |
N-[4-(3-chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide, an irreversible inhibitor of tyrosine kinases
|
WO2000042012A1
(en)
|
1999-01-13 |
2000-07-20 |
Bayer Corporation |
φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS
|
UA73492C2
(en)
|
1999-01-19 |
2005-08-15 |
|
Aromatic heterocyclic compounds as antiinflammatory agents
|
DE60033857T2
(de)
|
1999-01-22 |
2007-10-25 |
Kirin Beer K.K. |
Derivate des N-((Chinolinyl)oxy)-phenyl)-Harnstoffs und des N-((Chinazolinyl)oxy)-phenyl)-Harnstoffs mit Antitumor Aktivität
|
JP3270834B2
(ja)
|
1999-01-27 |
2002-04-02 |
ファイザー・プロダクツ・インク |
抗がん剤として有用なヘテロ芳香族二環式誘導体
|
UA71945C2
(en)
|
1999-01-27 |
2005-01-17 |
Pfizer Prod Inc |
Substituted bicyclic derivatives being used as anticancer agents
|
PL205557B1
(pl)
|
1999-02-10 |
2010-05-31 |
Astrazeneca Ab |
Pochodne indolu
|
GB9904103D0
(en)
|
1999-02-24 |
1999-04-14 |
Zeneca Ltd |
Quinoline derivatives
|
JP2000328080A
(ja)
|
1999-03-12 |
2000-11-28 |
Shin Etsu Chem Co Ltd |
シートベルト用低摩擦化処理剤
|
YU13200A
(sh)
|
1999-03-31 |
2002-10-18 |
Pfizer Products Inc. |
Postupci i intermedijeri za dobijanje anti-kancernih jedinjenja
|
CN101073668A
(zh)
|
1999-04-28 |
2007-11-21 |
德克萨斯大学董事会 |
用于通过选择性抑制vegf来治疗癌症的组合物和方法
|
WO2000071097A1
(fr)
|
1999-05-20 |
2000-11-30 |
Takeda Chemical Industries, Ltd. |
Composition contenant du sel d'acide ascorbique
|
JP4304357B2
(ja)
|
1999-05-24 |
2009-07-29 |
独立行政法人理化学研究所 |
完全長cDNAライブラリーの作成法
|
PE20010306A1
(es)
|
1999-07-02 |
2001-03-29 |
Agouron Pharma |
Compuestos de indazol y composiciones farmaceuticas que los contienen utiles para la inhibicion de proteina kinasa
|
JP2001047890A
(ja)
|
1999-08-06 |
2001-02-20 |
Toyota Motor Corp |
車両用パワープラントの制御装置
|
WO2001012600A1
(en)
|
1999-08-12 |
2001-02-22 |
Cor Therapeutics, Inc. |
INHIBITORS OF FACTOR Xa
|
AR025752A1
(es)
|
1999-09-28 |
2002-12-11 |
Bayer Corp |
Piridinas y piridacinas sustituidas con actividad de inhibicion de angiogenesis
|
UA75054C2
(uk)
|
1999-10-13 |
2006-03-15 |
Бьорінгер Інгельхайм Фарма Гмбх & Ко. Кг |
Заміщені в положенні 6 індолінони, їх одержання та їх застосування як лікарського засобу
|
US6762180B1
(en)
|
1999-10-13 |
2004-07-13 |
Boehringer Ingelheim Pharma Kg |
Substituted indolines which inhibit receptor tyrosine kinases
|
JP2001131071A
(ja)
|
1999-10-29 |
2001-05-15 |
Meiji Seika Kaisha Ltd |
非晶質および非晶質を含有する医薬組成物
|
AU784338B2
(en)
|
1999-11-01 |
2006-03-16 |
Curagen Corporation |
Differentially expressed genes involved in angiogenesis, the polypeptides encoded thereby, and methods of using the same
|
US20080241835A1
(en)
|
1999-11-01 |
2008-10-02 |
Genentech, Inc. |
Differentially expressed genes involved in angiogenesis, the polypeptides encoded thereby, and methods of using the same
|
MXPA02004879A
(es)
|
1999-11-16 |
2002-08-30 |
Boehringer Ingelheim Pharma |
Derivados de urea como agentes antiinflamatorios.
|
UA75055C2
(uk)
|
1999-11-30 |
2006-03-15 |
Пфайзер Продактс Інк. |
Похідні бензоімідазолу, що використовуються як антипроліферативний засіб, фармацевтична композиція на їх основі
|
MXPA02006263A
(es)
|
1999-12-22 |
2004-02-26 |
Sugen Inc |
Metodos de modulacion de la funcion de la cinasa de tirosina c-kit de la proteina con compuestos de indolinona.
|
WO2001047890A1
(fr)
|
1999-12-24 |
2001-07-05 |
Kirin Beer Kabushiki Kaisha |
Quinoline, derives de la quinazoline et medicaments contenant ces substances
|
DE60018216T2
(de)
|
1999-12-24 |
2006-02-16 |
Kyowa Hakko Kogyo Co., Ltd. |
Kondensierte purinderivate
|
ME00415B
(me)
|
2000-02-15 |
2011-10-10 |
Pharmacia & Upjohn Co Llc |
Pirol supstituisani 2-indol protein kinazni inhibitori
|
JP3657203B2
(ja)
|
2000-04-21 |
2005-06-08 |
エーザイ株式会社 |
銅クロロフィリン塩含有液剤組成物
|
CN1116047C
(zh)
|
2000-06-05 |
2003-07-30 |
华中科技大学 |
用泥鳅制成的护肝功能食品及其制备方法
|
JP2004512023A
(ja)
|
2000-06-09 |
2004-04-22 |
コリクサ コーポレイション |
結腸癌の治療および診断のための組成物および方法
|
AU2001277621A1
(en)
|
2000-08-09 |
2002-03-04 |
Astrazeneca Ab |
Antiangiogenic bicyclic derivatives
|
DE60126997T2
(de)
|
2000-10-20 |
2007-10-25 |
Eisai R&D Management Co., Ltd. |
Stickstoff-enthaltende aromatische ringverbindungen zur behandlung von tumorerkrankungen
|
TWI283575B
(en)
|
2000-10-31 |
2007-07-11 |
Eisai Co Ltd |
Medicinal compositions for concomitant use as anticancer agent
|
WO2002041882A2
(en)
|
2000-11-22 |
2002-05-30 |
Novartis Ag |
Combination comprising an agent decreasing vegf activity and an agent decreasing egf activity
|
JP2004517080A
(ja)
|
2000-11-29 |
2004-06-10 |
グラクソ グループ リミテッド |
Tie−2および/またはvegfr−2の阻害剤として有用なベンゾイミダゾール誘導体
|
US6544552B2
(en)
|
2001-01-11 |
2003-04-08 |
Particle And Coating Technologies, Inc. |
Method of producing porous tablets with improved dissolution properties
|
CN100523216C
(zh)
|
2001-03-02 |
2009-08-05 |
匹兹堡大学 |
Pcr方法
|
AU2002254152A1
(en)
|
2001-03-08 |
2002-09-24 |
Millennium Pharmaceuticals |
(homo) piperazine substituted quinolines for inhibiting the phosphorylation of kinases
|
JP2004525950A
(ja)
|
2001-04-06 |
2004-08-26 |
ワイス |
ラパマイシンとゲムシタビンまたはフルオロウラシルなどの、抗腫瘍剤の組み合わせ
|
US20040171068A1
(en)
|
2001-04-19 |
2004-09-02 |
Juergen Wehland |
Method for producing stable, regeneratable antibody arrays
|
TWI324154B
(es)
|
2001-04-27 |
2010-05-01 |
Kyowa Hakko Kirin Co Ltd |
|
JP3602513B2
(ja)
|
2001-04-27 |
2004-12-15 |
麒麟麦酒株式会社 |
アゾリル基を有するキノリン誘導体およびキナゾリン誘導体
|
JP2003026576A
(ja)
|
2001-05-09 |
2003-01-29 |
Eisai Co Ltd |
味覚改善製剤
|
US6812341B1
(en)
|
2001-05-11 |
2004-11-02 |
Ambion, Inc. |
High efficiency mRNA isolation methods and compositions
|
AU2002342335B2
(en)
|
2001-05-16 |
2006-02-02 |
Novartis Ag |
Combination comprising N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2pyrimidine-amine and a chemotherapeutic agent
|
AU2002303892A1
(en)
|
2001-05-30 |
2002-12-09 |
Jingrong Cui |
5-aralkylsulfonyl-3- (pyrrol-2-ylmethylidene)-2-indolinone derivatives as kinase inhibitors
|
EP2258366B1
(en)
|
2001-06-22 |
2013-04-03 |
Kirin Pharma Kabushiki Kaisha |
Quinoline derivatives capable of inhibiting autophosphorylation of hepatocyte growth factor receptors, and pharmaceutical composition comprising the same
|
US20030013208A1
(en)
|
2001-07-13 |
2003-01-16 |
Milagen, Inc. |
Information enhanced antibody arrays
|
GB0117144D0
(en)
|
2001-07-13 |
2001-09-05 |
Glaxo Group Ltd |
Process
|
JP4827154B2
(ja)
|
2001-07-25 |
2011-11-30 |
株式会社オーイズミ |
遊技装置
|
JP3088018U
(ja)
|
2001-08-02 |
2002-08-30 |
ユーエス工業株式会社 |
垂木支持用ブラケットを備えたパイプバンド
|
GB0119467D0
(en)
|
2001-08-09 |
2001-10-03 |
Smithkline Beecham Plc |
Novel compound
|
WO2003023360A2
(en)
|
2001-09-10 |
2003-03-20 |
Meso Scale Technologies, Llc |
Methods and apparatus for conducting multiple measurements on a sample
|
DE60228278D1
(de)
|
2001-09-20 |
2008-09-25 |
Ab Science |
Die verwendung von potenten, selektiven und nontoxischen c-kithemmern zur behandlung von interstitieller blasenentzündung
|
AU2002341881B2
(en)
|
2001-09-27 |
2008-05-08 |
Allergan, Inc. |
3-(arylamino)methylene-1, 3-dihydro-2h-indol-2-ones as kinase inhibitors
|
WO2003028711A2
(en)
|
2001-09-27 |
2003-04-10 |
Novartis Ag |
Use of c-kit inhibitors for the treatment of myeloma
|
EP1435959A2
(en)
|
2001-10-09 |
2004-07-14 |
University of Cincinnati |
Inhibitors of the egf receptor for the treatment of thyroid cancer
|
US7658924B2
(en)
|
2001-10-11 |
2010-02-09 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
US7521053B2
(en)
|
2001-10-11 |
2009-04-21 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
EP1447405A4
(en)
|
2001-10-17 |
2005-01-12 |
Kirin Brewery |
QUINOLINE OR QUINAZOLINE DERIVATIVES INHIBITING THE AUTOPHOSPHORYLATION OF FIBROBLAST GROWTH FACTOR RECEPTORS
|
ATE370123T1
(de)
|
2001-11-27 |
2007-09-15 |
Wyeth Corp |
3-cyanochinoline als inhibitoren von egf-r- und her2-kinasen
|
GB0201508D0
(en)
|
2002-01-23 |
2002-03-13 |
Novartis Ag |
Organic compounds
|
DK1916001T3
(da)
|
2002-03-04 |
2011-07-18 |
Imclone Llc |
KDR-specifikke humane antistoffer og anvendelser deraf
|
JP2003252737A
(ja)
|
2002-03-04 |
2003-09-10 |
Shin Etsu Chem Co Ltd |
口腔用組成物
|
EP1481678A4
(en)
|
2002-03-05 |
2009-12-30 |
Eisai R&D Man Co Ltd |
ANTITUMORAL AGENT CONTAINING A SULFONAMIDE-CONTAINING HETEROCYCLIC COMPOUND AND AN ANGIOGENESIS INHIBITOR
|
PL212421B1
(pl)
|
2002-03-12 |
2012-09-28 |
Bristol Myers Squibb Co |
Kompozycja farmaceutyczna w postaci zawiesiny kwasowego leku i sposób jej wytwarzania oraz sposób maskowania gorzkiego lub innego nieprzyjemnego smaku leku
|
JP2005520834A
(ja)
|
2002-03-20 |
2005-07-14 |
ダナ−ファーバー キャンサー インスティテュート,インコーポレイテッド |
小細胞肺癌の同定、診断、および治療のための方法および組成物
|
US6790852B2
(en)
|
2002-04-18 |
2004-09-14 |
Hoffmann-La Roche Inc. |
2-(2,6-dichlorophenyl)-diarylimidazoles
|
AU2003235838A1
(en)
|
2002-05-01 |
2003-11-17 |
Kirin Beer Kabushiki Kaisha |
Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of macrophage colony stimulating factor receptor
|
AR037647A1
(es)
|
2002-05-29 |
2004-12-01 |
Novartis Ag |
Derivados de diarilurea utiles para el tratamiento de enfermedades dependientes de la cinasa de proteina
|
UA77303C2
(en)
|
2002-06-14 |
2006-11-15 |
Pfizer |
Derivatives of thienopyridines substituted by benzocondensed heteroarylamide useful as therapeutic agents, pharmaceutical compositions and methods for their use
|
AU2003251968A1
(en)
|
2002-07-16 |
2004-02-02 |
Children's Medical Center Corporation |
A method for the modulation of angiogenesis
|
EP3656802A1
(en)
|
2002-07-22 |
2020-05-27 |
Aspen Aerogels Inc. |
Polyimide aerogels, carbon aerogels, and metal carbide aerogels and methods of making same
|
US7169936B2
(en)
|
2002-07-23 |
2007-01-30 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Indolinone derivatives substituted in the 6-position, their preparation and their use as medicaments
|
US7252976B2
(en)
|
2002-08-28 |
2007-08-07 |
Board Of Regents The University Of Texas System |
Quantitative RT-PCR to AC133 to diagnose cancer and monitor angiogenic activity in a cell sample
|
MXPA05001536A
(es)
|
2002-08-30 |
2005-04-19 |
Eisai Co Ltd |
Derivados aromaticos que contienen nitrogeno.
|
BR0315169A
(pt)
|
2002-10-09 |
2005-08-23 |
Kosan Biosciences Inc |
Referência cruzada a pedidos de patente relacionados
|
GB0223380D0
(en)
|
2002-10-09 |
2002-11-13 |
Astrazeneca Ab |
Combination therapy
|
JP4749660B2
(ja)
|
2002-10-16 |
2011-08-17 |
武田薬品工業株式会社 |
安定な固形製剤
|
US8697094B2
(en)
|
2002-10-16 |
2014-04-15 |
Takeda Pharmaceutical Company Limited |
Stable solid preparations
|
DE60305724T2
(de)
|
2002-10-21 |
2006-11-09 |
Warner-Lambert Co. Llc |
Tetrahydrochinolin-derivate als crth2 antagonisten
|
WO2004039782A1
(ja)
|
2002-10-29 |
2004-05-13 |
Kirin Beer Kabushiki Kaisha |
Flt3自己リン酸化を阻害するキノリン誘導体およびキナゾリン誘導体並びにそれらを含有する医薬組成物
|
DE10250711A1
(de)
|
2002-10-31 |
2004-05-19 |
Degussa Ag |
Pharmazeutische und kosmetische Zubereitungen
|
CA2502979A1
(en)
|
2002-11-06 |
2004-05-21 |
Cyclacel Limited |
Pharmaceutical composition comprising a cdk inhibitor and gemcitabine
|
GB0226434D0
(en)
|
2002-11-13 |
2002-12-18 |
Astrazeneca Ab |
Combination product
|
ITSV20020056A1
(it)
|
2002-11-14 |
2004-05-15 |
Alstom Transp Spa |
Dispositivo e metodo di verifica di motori software logici di comando di impianti ferroviari, in particolare di impianti di stazione
|
AR042042A1
(es)
|
2002-11-15 |
2005-06-08 |
Sugen Inc |
Administracion combinada de una indolinona con un agente quimioterapeutico para trastornos de proliferacion celular
|
ES2387909T3
(es)
|
2003-01-14 |
2012-10-03 |
Cytokinetics, Inc. |
Compuestos, composiciones y procedimientos de tratamiento de la insuficiencia cardiaca
|
JP3581361B1
(ja)
|
2003-02-17 |
2004-10-27 |
株式会社脳機能研究所 |
脳活動測定装置
|
CA2514875A1
(en)
|
2003-02-19 |
2004-09-02 |
Biovail Laboratories International Srl |
Rapid absorption selective 5-ht agonist formulations
|
BRPI0407827B8
(pt)
|
2003-02-26 |
2021-05-25 |
Sugen Inc |
compostos de aminoeteroarila como inibidores de proteína cinase e respectivos usos
|
WO2004078144A2
(en)
|
2003-03-05 |
2004-09-16 |
Celgene Corporation |
Diphenylethylene compounds and uses thereof
|
JPWO2004080462A1
(ja)
|
2003-03-10 |
2006-06-08 |
エーザイ株式会社 |
c−Kitキナーゼ阻害剤
|
TW201018661A
(en)
|
2003-03-14 |
2010-05-16 |
Ono Pharmaceutical Co |
Heterocyclic rinf having nitrogen atom derivatives and medicament containing the derivatives as active ingredient
|
JPWO2004081047A1
(ja)
|
2003-03-14 |
2006-06-29 |
大正製薬株式会社 |
モノクローナル抗体及びこれを産生するハイブリドーマ
|
CN1744881A
(zh)
*
|
2003-04-02 |
2006-03-08 |
普利瓦研究与发展有限公司 |
苦味减轻了的药物组合物
|
US20050014753A1
(en)
|
2003-04-04 |
2005-01-20 |
Irm Llc |
Novel compounds and compositions as protein kinase inhibitors
|
US20070117842A1
(en)
|
2003-04-22 |
2007-05-24 |
Itaru Arimoto |
Polymorph of 4-[3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy]-7-methoxy-6- quinolinecarboxamide and a process for the preparation of the same
|
EP1473043A1
(en)
|
2003-04-29 |
2004-11-03 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
Pharmaceutical combination for the treatment of diseases involving cell proliferation, migration or apotosis of myeloma cells, or angiogenesis
|
US7107104B2
(en)
|
2003-05-30 |
2006-09-12 |
Medtronic, Inc. |
Implantable cortical neural lead and method
|
JP2005008534A
(ja)
|
2003-06-17 |
2005-01-13 |
Soc De Conseils De Recherches & D'applications Scientifiques (Scras) |
抗癌剤及び癌の治療方法
|
WO2005004870A1
(en)
|
2003-07-10 |
2005-01-20 |
Astrazeneca Ab |
Use of the quinazoline derivative zd6474 combined with platinum compounds and optionally ionising radiation in the treatment of diseases associated with angiogenesis and/or increased vascular permeability
|
ATE395052T1
(de)
|
2003-08-15 |
2008-05-15 |
Ab Science |
Verwendung von c-kit-inhibitoren für die behandlung von typ-2-diabetes
|
CA2535896A1
(en)
|
2003-08-21 |
2005-03-10 |
Osi Pharmaceuticals, Inc. |
N-substituted benzimidazolyl c-kit inhibitors
|
DE602004017623D1
(de)
|
2003-08-21 |
2008-12-18 |
Osi Pharm Inc |
N-substituierte pyrazolyl-amidyl-benzimidazolyl-c-kit-inhibitoren
|
US7485658B2
(en)
|
2003-08-21 |
2009-02-03 |
Osi Pharmaceuticals, Inc. |
N-substituted pyrazolyl-amidyl-benzimidazolyl c-Kit inhibitors
|
US7312243B1
(en)
|
2003-08-29 |
2007-12-25 |
Jay Pravda |
Materials and methods for treatment of gastrointestinal disorders
|
JP2007505938A
(ja)
|
2003-09-23 |
2007-03-15 |
ノバルティス アクチエンゲゼルシャフト |
Vegf受容体阻害剤と化学療法剤の組み合わせ
|
EP2392564B1
(en)
|
2003-09-26 |
2013-10-23 |
Exelixis, Inc. |
c-Met modulators and methods of use
|
KR200340552Y1
(ko)
|
2003-10-08 |
2004-02-11 |
주식회사 엘지화학 |
창틀 내부에 블라인드 및 방범창 설치가 용이한 이중창틀
|
JP2005124034A
(ja)
|
2003-10-20 |
2005-05-12 |
Nippon Telegr & Teleph Corp <Ntt> |
発信者の特定及び発信者への呼び返しを可能とする回線設定方法
|
WO2005044788A1
(ja)
|
2003-11-11 |
2005-05-19 |
Eisai Co., Ltd. |
ウレア誘導体およびその製造方法
|
CA2546673A1
(en)
|
2003-11-28 |
2005-06-09 |
Novartis Ag |
Diaryl urea derivatives in the treatment of protein kinase dependent diseases
|
US6984403B2
(en)
|
2003-12-04 |
2006-01-10 |
Pfizer Inc. |
Azithromycin dosage forms with reduced side effects
|
AU2004296376B2
(en)
|
2003-12-05 |
2010-03-04 |
Bristol-Myers Squibb Company |
Inhibitors of type 2 vascular endothelial growth factor receptors
|
RS54033B1
(en)
|
2003-12-25 |
2015-10-30 |
Eisai R&D Management Co. Ltd. |
CRYSTAL FORM OF THE SALTS 4- (3-CHLORO-4- (CYCLOPROPYLAMINOCARBONYL) AMINO-PHENOXY) -7-METHOXY-6-HINOLINKARBOXAMIDE OR ITS SOLVATES AND THE PROCESS FOR THEIR PRODUCTION
|
BRPI0507373A
(pt)
|
2004-01-23 |
2007-07-10 |
Amgen Inc |
compostos e método de uso
|
CA2543859A1
(en)
|
2004-02-27 |
2005-09-09 |
Eisai Co., Ltd. |
Novel pyridine derivative and pyrimidine derivative (1)
|
KR20050091462A
(ko)
|
2004-03-12 |
2005-09-15 |
한국과학기술연구원 |
푸로피리미딘 화합물 및 이를 포함하는 ddr2 티로신키나아제 활성 저해제
|
US7459562B2
(en)
|
2004-04-23 |
2008-12-02 |
Bristol-Myers Squibb Company |
Monocyclic heterocycles as kinase inhibitors
|
AU2005245492A1
(en)
|
2004-05-21 |
2005-12-01 |
Novartis Vaccines And Diagnostics, Inc. |
Substituted quinoline derivatives as mitotic kinesin inhibitors
|
KR100986945B1
(ko)
|
2004-06-03 |
2010-10-12 |
에프. 호프만-라 로슈 아게 |
젬시타빈 및 egfr-억제제로의 치료
|
WO2006009765A2
(en)
*
|
2004-06-18 |
2006-01-26 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Methods for the identification and use of compounds suitable for the treatment of drug resistant cancer cells
|
US7173031B2
(en)
|
2004-06-28 |
2007-02-06 |
Bristol-Myers Squibb Company |
Pyrrolotriazine kinase inhibitors
|
US20050288521A1
(en)
|
2004-06-29 |
2005-12-29 |
Phytogen Life Sciences Inc. |
Semi-synthetic conversion of paclitaxel to docetaxel
|
EP1773826A4
(en)
|
2004-07-02 |
2009-06-03 |
Exelixis Inc |
MODULATORS OF C-MET AND THEIR METHOD OF USE
|
US8772269B2
(en)
|
2004-09-13 |
2014-07-08 |
Eisai R&D Management Co., Ltd. |
Use of sulfonamide-including compounds in combination with angiogenesis inhibitors
|
WO2006030947A1
(ja)
|
2004-09-13 |
2006-03-23 |
Eisai R & D Management Co., Ltd. |
スルホンアミド含有化合物の血管新生阻害物質との併用
|
US7306807B2
(en)
|
2004-09-13 |
2007-12-11 |
Wyeth |
Hemorrhagic feline calicivirus, calicivirus vaccine and method for preventing calicivirus infection or disease
|
KR20070053205A
(ko)
*
|
2004-09-17 |
2007-05-23 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
의약 조성물
|
US20060079494A1
(en)
|
2004-09-27 |
2006-04-13 |
Santi Daniel V |
Specific kinase inhibitors
|
AU2005290583A1
(en)
|
2004-10-01 |
2006-04-13 |
Eisai R & D Management Co., Ltd. |
Fine particles-containing composition and manufacturing method therefor
|
MX2007004247A
(es)
|
2004-10-19 |
2007-06-12 |
Amgen Inc |
Agentes de aglutinacion especifica a angiopoyetina-2.
|
EP1827445A2
(en)
|
2004-11-22 |
2007-09-05 |
King Pharmaceuticals Research and Development Inc. |
Enhancing treatment of cancer and hif-1 mediated disoders with adenosine a3 receptor antagonists
|
AU2005300239B2
(en)
|
2004-11-23 |
2009-08-06 |
Dong Wha Pharmaceutical Co., Ltd. |
N-Hydroxy -4-{5-[4-(5-isoproyl-2-methyl-1,3-thiazol-4-yl)phenoxy] pentoxy} benzamidine 2 methansulfonic acid salt
|
CA2587642C
(en)
|
2004-11-30 |
2013-04-09 |
Amgen Inc. |
Substituted heterocycles and methods of use
|
CN100341504C
(zh)
|
2004-12-01 |
2007-10-10 |
鲁南制药集团股份有限公司 |
佐米曲普坦速释制剂
|
EP1824843A2
(en)
|
2004-12-07 |
2007-08-29 |
Locus Pharmaceuticals, Inc. |
Inhibitors of protein kinases
|
ES2371083T3
(es)
|
2004-12-21 |
2011-12-27 |
Medimmune Limited |
Anticuerpos dirigidos contra la angiopoyetina-2 y usos de los mismos.
|
JP2006230816A
(ja)
|
2005-02-25 |
2006-09-07 |
H & A Investment:Kk |
サンダル用ホルダー
|
JP5106098B2
(ja)
|
2005-02-28 |
2012-12-26 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
スルホンアミド化合物の抗癌剤との新規併用
|
AU2006217692A1
(en)
|
2005-02-28 |
2006-08-31 |
Eisai R & D Management Co., Ltd. |
Novel combinational use of sulfonamide compound
|
US20080286282A1
(en)
|
2005-02-28 |
2008-11-20 |
Eisai R & D Management Co., Ltd. |
Novel Use of Sulfonamide Compound in Combination with Angiogenesis Inhibitor
|
CN105315373B
(zh)
|
2005-05-09 |
2018-11-09 |
小野药品工业株式会社 |
程序性死亡-1(pd-1)的人单克隆抗体及使用抗pd-1抗体来治疗癌症的方法
|
US7846941B2
(en)
|
2005-05-17 |
2010-12-07 |
Plexxikon, Inc. |
Compounds modulating c-kit and c-fms activity and uses therefor
|
PL1883397T3
(pl)
|
2005-05-17 |
2010-05-31 |
Actelion Pharmaceuticals Ltd |
Dyspergowalna tabletka bosertanu
|
PE20070100A1
(es)
|
2005-06-22 |
2007-03-10 |
Plexxikon Inc |
DERIVADOS DE PIRROLO[2,3-b]PIRIDINA COMO MODULADORES DE QUINASAS
|
US7550483B2
(en)
|
2005-06-23 |
2009-06-23 |
Eisai R&D Management Co., Ltd. |
Amorphous salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide and process for preparing the same
|
CA2606719C
(en)
|
2005-06-23 |
2010-08-10 |
Eisai R & D Management Co., Ltd. |
Amorphous salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide and process for producing the same
|
WO2007000347A2
(en)
|
2005-06-29 |
2007-01-04 |
Roselli, Patrizia |
Agonistic and antagonistic peptide mimetics of the vegf alpha-helix binding region for use in therapy
|
EA015535B1
(ru)
|
2005-07-11 |
2011-08-30 |
Никомед Данмарк Апс |
Формуляция бензимидазола
|
US8101799B2
(en)
|
2005-07-21 |
2012-01-24 |
Ardea Biosciences |
Derivatives of N-(arylamino) sulfonamides as inhibitors of MEK
|
US7820664B2
(en)
|
2007-01-19 |
2010-10-26 |
Bayer Schering Pharma Ag |
Inhibitors of MEK
|
JP2009502960A
(ja)
|
2005-07-27 |
2009-01-29 |
ザ・ボード・オブ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・テキサス・システム |
膵臓癌の処置のためのゲムシタビンおよびチロシンキナーゼ阻害剤を含む組み合わせ
|
US20100105031A1
(en)
|
2005-08-01 |
2010-04-29 |
Esai R & D Management Co., Ltd. |
Method for prediction of the efficacy of vascularization inhibitor
|
WO2007015578A1
(ja)
|
2005-08-02 |
2007-02-08 |
Eisai R & D Management Co., Ltd. |
血管新生阻害物質の効果を検定する方法
|
WO2007023768A1
(ja)
|
2005-08-24 |
2007-03-01 |
Eisai R & D Management Co., Ltd. |
新規ピリジン誘導体およびピリミジン誘導体(3)
|
WO2007026864A1
(ja)
|
2005-09-01 |
2007-03-08 |
Eisai R & D Management Co., Ltd. |
崩壊性の改善された医薬組成物の製造方法
|
CN1308012C
(zh)
|
2005-11-02 |
2007-04-04 |
广州中医药大学第二附属医院 |
一种治疗脑出血的中药组合物及其制备方法
|
US20090053236A1
(en)
|
2005-11-07 |
2009-02-26 |
Eisai R & D Management Co., Ltd. |
USE OF COMBINATION OF ANTI-ANGIOGENIC SUBSTANCE AND c-kit KINASE INHIBITOR
|
US20090247576A1
(en)
|
2005-11-22 |
2009-10-01 |
Eisai R & D Management Co., Ltd. |
Anti-tumor agent for multiple myeloma
|
ATE488237T1
(de)
|
2005-12-05 |
2010-12-15 |
Pfizer Prod Inc |
Verfahren zur behandlung von abnormalem zellwachstum
|
AR059066A1
(es)
|
2006-01-27 |
2008-03-12 |
Amgen Inc |
Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf)
|
KR100728926B1
(ko)
|
2006-03-20 |
2007-06-15 |
삼성전자주식회사 |
3축 힌지 구조를 갖는 휴대용 전자기기
|
RU2448708C3
(ru)
|
2006-05-18 |
2017-09-28 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Противоопухолевое средство против рака щитовидной железы
|
EP2062886B1
(en)
|
2006-08-23 |
2011-11-30 |
Eisai R&D Management Co., Ltd. |
Salt of phenoxypyridine derivative or crystal thereof and process for producing the same
|
WO2008026748A1
(fr)
|
2006-08-28 |
2008-03-06 |
Eisai R & D Management Co., Ltd. |
Agent antitumoral pour cancer gastrique non différencié
|
US7790885B2
(en)
|
2006-08-31 |
2010-09-07 |
Eisai R&D Management Co., Ltd. |
Process for preparing phenoxypyridine derivatives
|
CN101512017A
(zh)
|
2006-09-07 |
2009-08-19 |
阿斯利康(瑞典)有限公司 |
评价用靶向ret受体酪氨酸激酶的药物治疗的患者的方法
|
BRPI0719276A2
(pt)
|
2006-10-12 |
2014-04-29 |
Ptc Therapeutics Inc |
Métodos para tratar, prevenir ou controlar uma doença associada com uma mutação sem sentido, para tratar, prevenir ou reduzir tosse, para aumentar expressão de distrofina em músculo de um paciente e para administrar um composto.
|
JP2009184925A
(ja)
*
|
2006-11-02 |
2009-08-20 |
Dai Ichi Seiyaku Co Ltd |
5−(1h−1,2,3−トリアゾール−4−イル)−1h−ピラゾール誘導体
|
CN101616671A
(zh)
|
2007-01-19 |
2009-12-30 |
卫材R&D管理有限公司 |
胰腺癌治疗用组合物
|
CN101600694A
(zh)
|
2007-01-29 |
2009-12-09 |
卫材R&D管理有限公司 |
未分化型胃癌治疗用组合物
|
CN101605761A
(zh)
|
2007-02-23 |
2009-12-16 |
卫材R&D管理有限公司 |
对hgfr基因扩增细胞株显示优异的细胞增殖抑制效果和抗肿瘤效果的吡啶衍生物或嘧啶衍生物
|
KR20090116794A
(ko)
|
2007-03-05 |
2009-11-11 |
교와 핫꼬 기린 가부시키가이샤 |
의약 조성물
|
JPWO2008111441A1
(ja)
|
2007-03-05 |
2010-06-24 |
協和発酵キリン株式会社 |
医薬組成物
|
GB2448181B
(en)
|
2007-04-05 |
2011-11-09 |
Ford Global Tech Llc |
Vehicle headlight beam controls
|
US7807172B2
(en)
|
2007-06-13 |
2010-10-05 |
University Of Washington |
Methods and compositions for detecting thyroglobulin in a biological sample
|
PE20090368A1
(es)
|
2007-06-19 |
2009-04-28 |
Boehringer Ingelheim Int |
Anticuerpos anti-igf
|
CA2694646C
(en)
|
2007-07-30 |
2017-09-05 |
Ardea Biosciences, Inc. |
Combinations of mek inhibitors and raf kinase inhibitors and uses thereof
|
JP5638244B2
(ja)
|
2007-11-09 |
2014-12-10 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
血管新生阻害物質と抗腫瘍性白金錯体との併用
|
JP2009132660A
(ja)
|
2007-11-30 |
2009-06-18 |
Eisai R & D Management Co Ltd |
食道癌治療用組成物
|
JP5399926B2
(ja)
|
2008-01-29 |
2014-01-29 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
血管阻害物質とタキサンとの併用
|
GB2456907A
(en)
|
2008-01-30 |
2009-08-05 |
Astrazeneca Ab |
Method for determining subsequent VEGFR2 inhibitor therapy comprising measuring baseline VEGF level.
|
CA2753844A1
(en)
|
2008-03-05 |
2009-09-11 |
Vicus Therapeutics, Llc |
Compositions and methods for mucositis and oncology therapies
|
US8044240B2
(en)
|
2008-03-06 |
2011-10-25 |
Ardea Biosciences Inc. |
Polymorphic form of N-(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide and uses thereof
|
WO2009114335A2
(en)
|
2008-03-12 |
2009-09-17 |
Merck & Co., Inc. |
Pd-1 binding proteins
|
KR20110014149A
(ko)
|
2008-04-14 |
2011-02-10 |
아디아 바이오사이언스즈 인크. |
조성물 및 이것의 제조 및 사용 방법
|
WO2009137649A2
(en)
|
2008-05-07 |
2009-11-12 |
The Trustees Of The University Of Pennsylvania |
Methods for treating thyroid cancer
|
WO2009140549A1
(en)
|
2008-05-14 |
2009-11-19 |
Amgen Inc. |
Combinations vegf(r) inhibitors and hepatocyte growth factor (c-met) inhibitors for the treatment of cancer
|
WO2009150255A2
(en)
|
2008-06-13 |
2009-12-17 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Markers for predicting response and survival in anti-egfr treated patients
|
CA2729914A1
(en)
|
2008-07-11 |
2010-01-14 |
Novartis Ag |
Combination of (a) a phosphoinositide 3-kinase inhibitor and (b) a modulator of ras/raf/mek pathway
|
EP2350663A2
(en)
|
2008-10-21 |
2011-08-03 |
Bayer HealthCare LLC |
Identification of signature genes associated with hepatocellular carcinoma
|
WO2010086964A1
(ja)
|
2009-01-28 |
2010-08-05 |
株式会社 静岡カフェイン工業所 |
がん治療のための併用療法
|
AU2010279359A1
(en)
|
2009-08-07 |
2012-02-16 |
The Wistar Institute |
Compositions containing JARID1B inhibitors and methods for treating cancer
|
AU2010285740C1
(en)
*
|
2009-08-19 |
2016-03-17 |
Eisai R&D Management Co., Ltd. |
Quinoline derivative-containing pharmaceutical composition
|
CA2771606A1
(en)
|
2009-08-21 |
2011-02-24 |
Mount Sinai School Of Medicine Of New York University |
Methods of using cd44 fusion proteins to treat cancer
|
EP2293071A1
(en)
|
2009-09-07 |
2011-03-09 |
Universität Zu Köln |
Biomarker for colorectal cancer
|
CA2802644C
(en)
|
2010-06-25 |
2017-02-21 |
Eisai R & D Management Co., Ltd. |
Antitumor agent using compounds having kinase inhibitory effect in combination
|
KR20130091331A
(ko)
|
2010-07-16 |
2013-08-16 |
교와 핫꼬 기린 가부시키가이샤 |
함질소 방향족 복소환 유도체
|
EP3156800A1
(en)
|
2010-07-19 |
2017-04-19 |
F. Hoffmann-La Roche AG |
Blood plasma biomarkers for bevacizumab combination therapies for treatment of breast cancer
|
WO2012010546A1
(en)
|
2010-07-19 |
2012-01-26 |
F. Hoffmann-La Roche Ag |
Blood plasma biomarkers for bevacizumab combination therapies for treatment of pancreatic cancer
|
BR112013001429A2
(pt)
|
2010-07-19 |
2016-05-31 |
Hoffmann La Roche |
método de identificação de pacientes com maior probabilidade de responder a terapia anticâncer
|
CA2804246A1
(en)
|
2010-07-19 |
2012-01-26 |
F. Hoffmann-La Roche Ag |
Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy
|
WO2012019300A1
(en)
|
2010-08-10 |
2012-02-16 |
Siu K W Michael |
Endometrial cancer biomarkers and methods of identifying and using same
|
US20120077837A1
(en)
|
2010-09-24 |
2012-03-29 |
Eisai R&D Management Co., Ltd. |
Anti-tumor agent
|
SG190735A1
(en)
|
2011-02-28 |
2013-07-31 |
Calitor Sciences Llc |
Substituted quinoline compounds and methods of use
|
CA2864394C
(en)
|
2011-03-02 |
2021-10-19 |
Jack Roth |
A method of predicting a response to a tusc2 therapy
|
WO2012122444A1
(en)
|
2011-03-10 |
2012-09-13 |
Provectus Pharmaceuticals, Inc. |
Combination of local and systemic immunomodulative therapies for enhanced treatment of cancer
|
CA2828946C
(en)
|
2011-04-18 |
2016-06-21 |
Eisai R&D Management Co., Ltd. |
Therapeutic agent for tumor
|
WO2012154935A1
(en)
|
2011-05-12 |
2012-11-15 |
Eisai R&D Management Co., Ltd. |
Biomarkers that are predictive of responsiveness or non-responsiveness to treatment with lenvatinib or a pharmaceutically acceptable salt thereof
|
JP5952810B2
(ja)
|
2011-05-17 |
2016-07-13 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
血管新生阻害剤の効果を予測する方法
|
WO2012166899A2
(en)
|
2011-06-03 |
2012-12-06 |
Eisai R&D Management Co., Ltd. |
Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds
|
JP6238459B2
(ja)
|
2011-08-01 |
2017-11-29 |
ジェネンテック, インコーポレイテッド |
Pd−1軸結合アンタゴニストとmek阻害剤を使用する癌の治療方法
|
AU2013201121A1
(en)
|
2011-09-20 |
2013-04-04 |
Vical Incorporated |
Synergistic anti-tumor efficacy using alloantigen combination immunotherapy
|
AR090263A1
(es)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
|
SG10201700698WA
(en)
|
2012-05-15 |
2017-02-27 |
Bristol Myers Squibb Co |
Cancer immunotherapy by disrupting pd-1/pd-l1 signaling
|
WO2013171287A1
(en)
|
2012-05-16 |
2013-11-21 |
Boehringer Ingelheim International Gmbh |
Combination of cd37 antibodies with ice (ifosfamide, carboplatin, etoposide)
|
RS56624B1
(sr)
|
2012-10-02 |
2018-03-30 |
Bristol Myers Squibb Co |
Kombinacija anti-kir antitela i anti-pd-1 antitela u lečenju kancera
|
JP6466339B2
(ja)
|
2012-12-04 |
2019-02-06 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
乳がんの処置におけるエリブリンの使用
|
EP2945652B1
(en)
|
2013-01-18 |
2021-07-07 |
Foundation Medicine, Inc. |
Methods of treating cholangiocarcinoma
|
JP5654715B1
(ja)
|
2013-02-28 |
2015-01-14 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
テトラヒドロイミダゾ[1,5−d][1,4]オキサゼピン誘導体(TETRAHYDROIMIDAZO[1,5−d][1,4]OXAZEPINEDERIVATIVE)
|
CA2912219C
(en)
|
2013-05-14 |
2021-11-16 |
Eisai R&D Management Co., Ltd. |
Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds
|
KR102265952B1
(ko)
|
2013-06-26 |
2021-06-16 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
암 치료 병용요법으로서 에리불린 및 렌바티닙의 용도
|
US9174998B2
(en)
|
2013-12-25 |
2015-11-03 |
Eisai R&D Management Co., Ltd. |
(6S,9aS)-N-benzyl-6-[(4-hydroxyphenyl)methyl]-4,7-dioxo-8-({6-[3-(piperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-2-(prop-2-en-1-yl)-octahydro-1H-pyrazino[2,1-c][1,2,4]triazine-1-carboxamide compound
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
RU2744880C1
(ru)
|
2014-02-04 |
2021-03-16 |
Инсайт Корпорейшн |
Комбинация антагониста pd-1 и ингибитора ido1 для лечения рака
|
KR20230043234A
(ko)
|
2014-08-28 |
2023-03-30 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
고순도의 퀴놀린 유도체 및 이를 제조하는 방법
|
KR20170122809A
(ko)
|
2015-03-04 |
2017-11-06 |
머크 샤프 앤드 돔 코포레이션 |
암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합
|
CA2988707C
(en)
|
2015-06-16 |
2023-10-10 |
Eisai R&D Management Co., Ltd. |
Combination of cbp/catenin inhibitor and immune checkpoint inhibitor for treating cancer
|
ES2870013T3
(es)
|
2015-06-23 |
2021-10-26 |
Eisai R&D Man Co Ltd |
Cristal de (6S,9aS)-N-bencil-8-({6-[3-(4-etilpiperazin-1-il)azetidin-1-il]piridin-2-il}metil)-6-(2-fluoro-4-hidroxibencil)-4,7-dioxo-2-(prop-2-en-1-il)hexahidro-2H-pirazino[2,1-c][1,2,4]triazin-1(6H)-carboxamida
|
US20200375975A1
(en)
|
2016-04-15 |
2020-12-03 |
Eisai R&D Management Co., Ltd. |
Treatment of Renal Cell Carcinoma with Lenvatinib and Everolimus
|