CY1116424T1 - Παραγωγο αδενινης ως αναστολεας ρι3κ - Google Patents

Παραγωγο αδενινης ως αναστολεας ρι3κ

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Publication number
CY1116424T1
CY1116424T1 CY20151100458T CY151100458T CY1116424T1 CY 1116424 T1 CY1116424 T1 CY 1116424T1 CY 20151100458 T CY20151100458 T CY 20151100458T CY 151100458 T CY151100458 T CY 151100458T CY 1116424 T1 CY1116424 T1 CY 1116424T1
Authority
CY
Cyprus
Prior art keywords
risk
adeninis
production
chemicals
kinase activity
Prior art date
Application number
CY20151100458T
Other languages
English (en)
Inventor
Pingda Ren
Yi Liu
Troy Edward Wilson
Liansheng Li
Katrina Chan
Christian Rommel
Original Assignee
Intellikine, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intellikine, Llc filed Critical Intellikine, Llc
Publication of CY1116424T1 publication Critical patent/CY1116424T1/el

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    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract

Οι χημικές ολότητες που ρυθμίζουν δραστικότητα κινάσης ΡΙ3, φαρμακευτικές συνθέσεις που περιέχουν τις χημικές ολότητες και μέθοδοι χρήσης αυτών των χημικών ολοτήτων για θεραπεία ασθενειών και καταστάσεων που συνδυάζονται με δραστικότητα κινάσης ΡΙ3 περιγράφονται στο παρόν.
CY20151100458T 2009-07-15 2015-05-22 Παραγωγο αδενινης ως αναστολεας ρι3κ CY1116424T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/503,776 US8193182B2 (en) 2008-01-04 2009-07-15 Substituted isoquinolin-1(2H)-ones, and methods of use thereof
EP10800175.1A EP2456444B1 (en) 2009-07-15 2010-07-15 Adenine derivative as pi3k inhibitor

Publications (1)

Publication Number Publication Date
CY1116424T1 true CY1116424T1 (el) 2017-02-08

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CY20151100458T CY1116424T1 (el) 2009-07-15 2015-05-22 Παραγωγο αδενινης ως αναστολεας ρι3κ

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US (12) US8193182B2 (el)
EP (4) EP2918589B1 (el)
JP (2) JP5944313B2 (el)
KR (1) KR101680406B1 (el)
CN (3) CN102711767B (el)
AU (1) AU2010274075B2 (el)
BR (1) BR112012000968B8 (el)
CA (1) CA2768307C (el)
CY (1) CY1116424T1 (el)
DK (1) DK2456444T3 (el)
ES (1) ES2538853T3 (el)
HK (2) HK1170491A1 (el)
HR (1) HRP20150586T1 (el)
HU (1) HUS2100048I1 (el)
IL (2) IL217181A (el)
IN (1) IN2012DN00943A (el)
LT (1) LTPA2021526I1 (el)
MX (2) MX2012000626A (el)
MY (2) MY168762A (el)
NL (1) NL301140I2 (el)
NZ (3) NZ706506A (el)
PH (2) PH12015502432A1 (el)
PL (1) PL2456444T3 (el)
PT (1) PT2456444E (el)
RU (2) RU2582676C3 (el)
SG (2) SG177641A1 (el)
SI (1) SI2456444T1 (el)
SM (1) SMT201500141B (el)
UA (2) UA109878C2 (el)
WO (1) WO2011008302A1 (el)
ZA (1) ZA201200254B (el)

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ZA201200254B (en) 2013-03-27
US20160158239A1 (en) 2016-06-09
SMT201500141B (it) 2015-09-07

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