SG10201911665UA - Heterocyclic compounds as ret kinase inhibitors - Google Patents
Heterocyclic compounds as ret kinase inhibitorsInfo
- Publication number
- SG10201911665UA SG10201911665UA SG10201911665UA SG10201911665UA SG10201911665UA SG 10201911665U A SG10201911665U A SG 10201911665UA SG 10201911665U A SG10201911665U A SG 10201911665UA SG 10201911665U A SG10201911665U A SG 10201911665UA SG 10201911665U A SG10201911665U A SG 10201911665UA
- Authority
- SG
- Singapore
- Prior art keywords
- kinase inhibitors
- heterocyclic compounds
- ret kinase
- ret
- heterocyclic
- Prior art date
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 229940043355 kinase inhibitor Drugs 0.000 title 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201606631 | 2016-04-15 | ||
| GB201619277 | 2016-11-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201911665UA true SG10201911665UA (en) | 2020-01-30 |
Family
ID=58633035
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201911665UA SG10201911665UA (en) | 2016-04-15 | 2017-04-18 | Heterocyclic compounds as ret kinase inhibitors |
| SG11201808878UA SG11201808878UA (en) | 2016-04-15 | 2017-04-18 | Heterocyclic compounds as ret kinase inhibitors |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201808878UA SG11201808878UA (en) | 2016-04-15 | 2017-04-18 | Heterocyclic compounds as ret kinase inhibitors |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US10954241B2 (en) |
| EP (2) | EP3960180A1 (en) |
| JP (3) | JP6943876B2 (en) |
| KR (2) | KR102390578B1 (en) |
| CN (2) | CN115650985A (en) |
| AU (3) | AU2017250448C1 (en) |
| BR (2) | BR122023026297A2 (en) |
| CA (1) | CA3020778A1 (en) |
| CY (1) | CY1124478T1 (en) |
| DK (1) | DK3442980T3 (en) |
| ES (1) | ES2886587T3 (en) |
| HR (1) | HRP20211362T1 (en) |
| HU (1) | HUE056135T2 (en) |
| IL (3) | IL289793B2 (en) |
| LT (1) | LT3442980T (en) |
| MX (2) | MX2018012609A (en) |
| PL (1) | PL3442980T3 (en) |
| PT (1) | PT3442980T (en) |
| RS (1) | RS62322B1 (en) |
| RU (1) | RU2742115C2 (en) |
| SG (2) | SG10201911665UA (en) |
| SI (1) | SI3442980T1 (en) |
| WO (1) | WO2017178844A1 (en) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CR20170098A (en) | 2010-05-20 | 2017-07-17 | Array Biopharma Inc | MACROCICLICAL COMPOUNDS AS QUINASA TRK INHIBITORS |
| MX2018000577A (en) | 2015-07-16 | 2018-09-05 | Array Biopharma Inc | Substituted pyrazolo[1,5-a]pyridine compounds as ret kinase inhibitors. |
| HRP20231681T1 (en) | 2015-11-02 | 2024-04-12 | Blueprint Medicines Corporation | Inhibitors of ret |
| DK3442535T3 (en) * | 2016-04-15 | 2022-09-05 | Cancer Research Tech Ltd | HETEROCYCLIC SUBSTANCES AS RET KINASE INHIBITORS |
| KR102390578B1 (en) | 2016-04-15 | 2022-04-26 | 캔써 리서치 테크놀로지 리미티드 | Heterocyclic compounds as RET kinase inhibitors |
| TWI704148B (en) | 2016-10-10 | 2020-09-11 | 美商亞雷生物製藥股份有限公司 | Substituted pyrazolo[1,5-a]pyridine compounds as ret kinase inhibitors |
| JOP20190077A1 (en) | 2016-10-10 | 2019-04-09 | Array Biopharma Inc | Substituted pyrazolo[1,5-a]pyridine compounds as ret kinase inhibitors |
| EP3571203B1 (en) | 2017-01-18 | 2023-06-07 | Array BioPharma Inc. | Substituted pyrazolo[1,5-a]pyrazine compounds as ret kinase inhibitors |
| WO2018136663A1 (en) | 2017-01-18 | 2018-07-26 | Array Biopharma, Inc. | Ret inhibitors |
| JOP20190213A1 (en) | 2017-03-16 | 2019-09-16 | Array Biopharma Inc | Macrocyclic compounds as ros1 kinase inhibitors |
| GB201705971D0 (en) | 2017-04-13 | 2017-05-31 | Cancer Res Tech Ltd | Inhibitor compounds |
| TWI791053B (en) | 2017-10-10 | 2023-02-01 | 美商亞雷生物製藥股份有限公司 | Crystalline forms of 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile and pharmaceutical composition thereof |
| TWI812649B (en) | 2017-10-10 | 2023-08-21 | 美商絡速藥業公司 | Formulations of 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile |
| KR20190043437A (en) | 2017-10-18 | 2019-04-26 | 씨제이헬스케어 주식회사 | Heterocylic compound as a protein kinase inhibitor |
| CN111971286B (en) | 2018-01-18 | 2023-04-14 | 阿雷生物药品公司 | Substituted pyrrolo [2,3-d ] pyrimidine compounds as RET kinase inhibitors |
| JP7061195B2 (en) * | 2018-01-18 | 2022-04-27 | アレイ バイオファーマ インコーポレイテッド | Substituted pyrazolo [3,4-d] pyrimidine compound as a RET kinase inhibitor |
| US11472802B2 (en) | 2018-01-18 | 2022-10-18 | Array Biopharma Inc. | Substituted pyrazolyl[4,3-c]pyridine compounds as RET kinase inhibitors |
| MX2020010417A (en) | 2018-04-03 | 2021-01-08 | Blueprint Medicines Corp | Ret inhibitor for use in treating cancer having a ret alteration. |
| AU2019249721A1 (en) * | 2018-04-05 | 2020-09-17 | Merck Patent Gmbh | Heteroaryl compounds as type II IRAK inhibitors and uses hereof |
| WO2020055672A1 (en) | 2018-09-10 | 2020-03-19 | Array Biopharma Inc. | Fused heterocyclic compounds as ret kinase inhibitors |
| EP4364798A2 (en) | 2018-10-05 | 2024-05-08 | Annapurna Bio Inc. | Compounds and compositions for treating conditions associated with apj receptor activity |
| EP3950685A4 (en) * | 2019-04-03 | 2022-12-14 | Guangzhou Baiyunshan Pharmaceutical Holdings Co., Ltd. Baiyunshan Pharmaceutical General Factory | Pyrazolopyridine compound as ret inhibitor and application thereof |
| JP7461605B2 (en) * | 2020-02-20 | 2024-04-04 | 広州白雲山医薬集団股▲フン▼有限公司白雲山制薬総廠 | Quinoline Compounds |
| CN113214294A (en) * | 2020-06-10 | 2021-08-06 | 深圳铂立健医药有限公司 | Tricyclic compound, pharmaceutical composition and application thereof |
| WO2022076975A1 (en) | 2020-10-05 | 2022-04-14 | Enliven Therapeutics, Inc. | 5- and 6-azaindole compounds for inhibition of bcr-abl tyrosine kinases |
| TW202241419A (en) * | 2020-12-22 | 2022-11-01 | 美商基利科學股份有限公司 | 6-substituted indole compounds |
| US20240059673A1 (en) * | 2020-12-22 | 2024-02-22 | Gilead Sciences, Inc. | Substituted indole compounds |
| AU2022257039A1 (en) | 2021-04-16 | 2023-10-05 | Gilead Sciences, Inc. | Thienopyrrole compounds |
| CN113248518B (en) * | 2021-06-21 | 2022-03-25 | 山东大学 | Pyrimidine piperazine derivative and preparation method and application thereof |
| WO2023064843A1 (en) | 2021-10-15 | 2023-04-20 | Stemline Therapeutics, Inc. | Inhibitors of mutant ret kinases for use in treating cancer |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0322779A3 (en) | 1987-12-29 | 1991-05-08 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzolactam compounds and pharmaceutical uses thereof |
| US5480883A (en) | 1991-05-10 | 1996-01-02 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
| DE1140938T1 (en) * | 1999-01-11 | 2003-01-09 | Princeton University Princeton | KINASE INHIBITORS WITH HIGH AFFINITY FOR TARGET DETECTION AND THEIR USE |
| US7119200B2 (en) | 2002-09-04 | 2006-10-10 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
| US7429596B2 (en) | 2003-06-20 | 2008-09-30 | The Regents Of The University Of California | 1H-pyrrolo [2,3-D] pyrimidine derivatives and methods of use thereof |
| US9512125B2 (en) | 2004-11-19 | 2016-12-06 | The Regents Of The University Of California | Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents |
| US9271963B2 (en) | 2005-03-03 | 2016-03-01 | Universitat Des Saarlandes | Selective inhibitors of human corticosteroid synthases |
| PT1951724E (en) | 2005-11-17 | 2011-08-02 | Osi Pharm Inc | Fused bicyclic mtor inhibitors |
| AR057960A1 (en) | 2005-12-02 | 2007-12-26 | Osi Pharm Inc | BICYCLE PROTEIN QUINASE INHIBITORS |
| JP5512975B2 (en) | 2005-12-29 | 2014-06-04 | アッヴィ・インコーポレイテッド | Protein kinase inhibitors |
| GB0610242D0 (en) | 2006-05-23 | 2006-07-05 | Novartis Ag | Organic compounds |
| JP2008063278A (en) | 2006-09-07 | 2008-03-21 | Fujifilm Finechemicals Co Ltd | Method for producing 1-pyridin-4-yl-indole |
| KR101315610B1 (en) | 2006-09-22 | 2013-10-10 | 파마시클릭스, 인코포레이티드 | Inhibitors of bruton's tyrosine kinase |
| US20090274698A1 (en) * | 2007-07-06 | 2009-11-05 | Shripad Bhagwat | Combination anti-cancer therapy |
| MX2010007418A (en) | 2008-01-04 | 2010-11-12 | Intellikine Inc | Certain chemical entities, compositions and methods. |
| US8193182B2 (en) | 2008-01-04 | 2012-06-05 | Intellikine, Inc. | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
| WO2010006072A2 (en) | 2008-07-08 | 2010-01-14 | The Regents Of The University Of California | Mtor modulators and uses thereof |
| JP5788316B2 (en) | 2008-07-08 | 2015-09-30 | インテリカイン， エルエルシー | Kinase inhibitors and methods of use |
| JP5731978B2 (en) | 2008-09-26 | 2015-06-10 | インテリカイン， エルエルシー | Heterocyclic kinase inhibitor |
| US20110269779A1 (en) | 2008-11-18 | 2011-11-03 | Intellikine, Inc. | Methods and compositions for treatment of ophthalmic conditions |
| KR101061599B1 (en) * | 2008-12-05 | 2011-09-02 | 한국과학기술연구원 | Novel indazole derivatives that are protein kinase inhibitors for the treatment of abnormal cell growth diseases, pharmaceutically acceptable salts thereof, and pharmaceutical compositions containing the same as active ingredients |
| MX352661B (en) | 2009-11-05 | 2017-12-04 | Rhizen Pharmaceuticals S A Star | Novel benzopyran kinase modulators. |
| EP2528919B1 (en) | 2010-01-28 | 2016-11-02 | University of Washington | Compositions and methods for treating toxoplasmosis. cryptosporidiosis and other apicomplexan protozoan related diseases |
| US9765037B2 (en) | 2010-01-28 | 2017-09-19 | University Of Washington Through Its Center For Commercialization | Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases |
| WO2011153553A2 (en) | 2010-06-04 | 2011-12-08 | The Regents Of The University Of California | Methods and compositions for kinase inhibition |
| US20130296316A1 (en) | 2010-07-09 | 2013-11-07 | Michael P. Pollastri | Antiparasitic Agents Based On mTOR Inhibitors |
| AR085397A1 (en) | 2011-02-23 | 2013-09-25 | Intellikine Inc | COMBINATION OF QUINASA INHIBITORS AND THEIR USES |
| CN103703174B (en) | 2011-05-04 | 2017-05-10 | 因特利凯有限责任公司 | Combination pharmaceutical compositions and uses thereof |
| US9358229B2 (en) | 2011-08-10 | 2016-06-07 | Novartis Pharma Ag | JAK PI3K/mTOR combination therapy |
| JP6342805B2 (en) * | 2011-09-02 | 2018-06-13 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Substituted pyrazolo [3,4-D] pyrimidine and uses thereof |
| WO2013070976A1 (en) | 2011-11-08 | 2013-05-16 | Intellikine, Llc | Treatment regimens using multiple pharmaceutical agents |
| EP2793893A4 (en) | 2011-11-23 | 2015-07-08 | Intellikine Llc | Enhanced treatment regimens using mtor inhibitors |
| US8501724B1 (en) | 2012-01-31 | 2013-08-06 | Pharmacyclics, Inc. | Purinone compounds as kinase inhibitors |
| US8889730B2 (en) | 2012-04-10 | 2014-11-18 | Pfizer Inc. | Indole and indazole compounds that activate AMPK |
| US9738610B2 (en) | 2012-09-24 | 2017-08-22 | Whitehead Institute For Biomedical Research | Indazole derivatives and uses thereof |
| GB201217285D0 (en) | 2012-09-27 | 2012-11-14 | Univ Central Lancashire | Indole derivatives |
| JP2016512835A (en) | 2013-03-15 | 2016-05-09 | インテリカイン， エルエルシー | Combinations of kinase inhibitors and their use |
| CN105209042B (en) | 2013-03-22 | 2019-03-08 | 米伦纽姆医药公司 | The combination of 1/2 inhibitor of catalytic MTORC and selective aurora A kinase inhibitor |
| US20160272645A1 (en) | 2013-10-18 | 2016-09-22 | Medivation Technologies, Inc. | Heterocyclic Compounds and Methods of Use |
| WO2015058084A1 (en) | 2013-10-18 | 2015-04-23 | Medivation Technologies, Inc. | Heterocyclic compounds and methods of use |
| GB201321146D0 (en) | 2013-11-29 | 2014-01-15 | Cancer Rec Tech Ltd | Quinazoline compounds |
| ES2792036T3 (en) * | 2014-11-14 | 2020-11-06 | Nerviano Medical Sciences Srl | 6-amino-7-bicyclo-7-deaza-purine derivatives as kinase inhibitors |
| CA2974702C (en) | 2015-01-26 | 2023-10-10 | University Of Washington | Compositions and methods for treating toxoplasmosis, cryptosporidiosis and other apicomplexan protozoan related diseases |
| US10550124B2 (en) | 2015-08-13 | 2020-02-04 | San Diego State University Foundation | Atropisomerism for increased kinase inhibitor selectivity |
| WO2017160717A2 (en) | 2016-03-15 | 2017-09-21 | Memorial Sloan Kettering Cancer Center | Method of treating diseases using kinase modulators |
| KR102390578B1 (en) | 2016-04-15 | 2022-04-26 | 캔써 리서치 테크놀로지 리미티드 | Heterocyclic compounds as RET kinase inhibitors |
| DK3442535T3 (en) * | 2016-04-15 | 2022-09-05 | Cancer Research Tech Ltd | HETEROCYCLIC SUBSTANCES AS RET KINASE INHIBITORS |
-
2017
- 2017-04-18 KR KR1020187032842A patent/KR102390578B1/en active IP Right Grant
- 2017-04-18 BR BR122023026297-2A patent/BR122023026297A2/en unknown
- 2017-04-18 BR BR112018071097-0A patent/BR112018071097B1/en active IP Right Grant
- 2017-04-18 EP EP21172597.3A patent/EP3960180A1/en active Pending
- 2017-04-18 WO PCT/GB2017/051076 patent/WO2017178844A1/en active Application Filing
- 2017-04-18 MX MX2018012609A patent/MX2018012609A/en unknown
- 2017-04-18 DK DK17719687.0T patent/DK3442980T3/en active
- 2017-04-18 SG SG10201911665UA patent/SG10201911665UA/en unknown
- 2017-04-18 RS RS20211115A patent/RS62322B1/en unknown
- 2017-04-18 JP JP2018554114A patent/JP6943876B2/en active Active
- 2017-04-18 PL PL17719687T patent/PL3442980T3/en unknown
- 2017-04-18 CN CN202211269931.2A patent/CN115650985A/en active Pending
- 2017-04-18 CA CA3020778A patent/CA3020778A1/en active Pending
- 2017-04-18 US US16/093,854 patent/US10954241B2/en active Active
- 2017-04-18 PT PT177196870T patent/PT3442980T/en unknown
- 2017-04-18 SG SG11201808878UA patent/SG11201808878UA/en unknown
- 2017-04-18 KR KR1020227013172A patent/KR20220054894A/en not_active Application Discontinuation
- 2017-04-18 EP EP17719687.0A patent/EP3442980B1/en active Active
- 2017-04-18 LT LTEPPCT/GB2017/051076T patent/LT3442980T/en unknown
- 2017-04-18 AU AU2017250448A patent/AU2017250448C1/en active Active
- 2017-04-18 SI SI201730892T patent/SI3442980T1/en unknown
- 2017-04-18 HU HUE17719687A patent/HUE056135T2/en unknown
- 2017-04-18 RU RU2018138471A patent/RU2742115C2/en active
- 2017-04-18 ES ES17719687T patent/ES2886587T3/en active Active
- 2017-04-18 CN CN201780031509.4A patent/CN109195972B/en active Active
- 2017-04-18 IL IL289793A patent/IL289793B2/en unknown
- 2017-04-18 IL IL297192A patent/IL297192A/en unknown
-
2018
- 2018-10-07 IL IL262185A patent/IL262185B/en unknown
- 2018-10-15 MX MX2021013110A patent/MX2021013110A/en unknown
-
2020
- 2020-08-18 AU AU2020220079A patent/AU2020220079B2/en active Active
-
2021
- 2021-02-02 US US17/165,151 patent/US11548896B2/en active Active
- 2021-08-26 HR HRP20211362TT patent/HRP20211362T1/en unknown
- 2021-09-06 CY CY20211100784T patent/CY1124478T1/en unknown
- 2021-09-07 JP JP2021145468A patent/JP2021193108A/en active Pending
-
2022
- 2022-06-06 AU AU2022203916A patent/AU2022203916A1/en active Pending
- 2022-11-22 US US17/992,049 patent/US20230339954A1/en active Pending
-
2023
- 2023-08-10 JP JP2023131211A patent/JP2023159230A/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL289793A (en) | Heterocyclic compounds as ret kinase inhibitors | |
| RS63609B1 (en) | Heterocyclic compounds as ret kinase inhibitors | |
| HUS2400003I1 (en) | Compounds useful as kinase inhibitors | |
| IL276509A (en) | Heterocyclic compounds as kinase inhibitors | |
| HUE059324T2 (en) | Heterocyclic compounds as pi3k-gamma inhibitors | |
| IL255750A (en) | Heterocyclic compounds as kinase inhibitors | |
| PT3609898T (en) | Compounds useful as ret inhibitors | |
| IL266789A (en) | Heterocyclic compounds as kinase inhibitors | |
| GB201613945D0 (en) | Compounds useful as kinase inhibitors | |
| GB201522245D0 (en) | Compounds useful as kinase inhibitors |