TR201905218T4 - Nörodejenerati̇f hastaliklarin tedavi̇si̇ i̇çi̇n yararli vi̇tanoli̇dler. - Google Patents
Nörodejenerati̇f hastaliklarin tedavi̇si̇ i̇çi̇n yararli vi̇tanoli̇dler. Download PDFInfo
- Publication number
- TR201905218T4 TR201905218T4 TR2019/05218T TR201905218T TR201905218T4 TR 201905218 T4 TR201905218 T4 TR 201905218T4 TR 2019/05218 T TR2019/05218 T TR 2019/05218T TR 201905218 T TR201905218 T TR 201905218T TR 201905218 T4 TR201905218 T4 TR 201905218T4
- Authority
- TR
- Turkey
- Prior art keywords
- treatment
- neurodegenerative diseases
- vitanolides
- useful
- vitanolide
- Prior art date
Links
- 208000015122 neurodegenerative disease Diseases 0.000 title abstract 2
- 230000004770 neurodegeneration Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Burada formül (I)'e ilişkin doğal vitanolid ürünleri, R1-R4 burada tanımlandığı gibidir, ve bunların nörodejeneratif hastalıkların tedavisinde farmasötik kullanımları sağlanmaktadır.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361908455P | 2013-11-25 | 2013-11-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201905218T4 true TR201905218T4 (tr) | 2019-05-21 |
Family
ID=52023694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2019/05218T TR201905218T4 (tr) | 2013-11-25 | 2014-11-25 | Nörodejenerati̇f hastaliklarin tedavi̇si̇ i̇çi̇n yararli vi̇tanoli̇dler. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10351590B2 (tr) |
| EP (1) | EP3074414B1 (tr) |
| JP (1) | JP6517833B2 (tr) |
| KR (1) | KR20160137945A (tr) |
| CN (1) | CN105940010B (tr) |
| AU (1) | AU2014352629B2 (tr) |
| BR (1) | BR112016012002A2 (tr) |
| CA (1) | CA2931064C (tr) |
| ES (1) | ES2728870T3 (tr) |
| MX (1) | MX364528B (tr) |
| PL (1) | PL3074414T3 (tr) |
| TR (1) | TR201905218T4 (tr) |
| WO (1) | WO2015077780A1 (tr) |
| ZA (1) | ZA201603117B (tr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019116069A1 (en) * | 2017-12-11 | 2019-06-20 | Ethnodyne | Compounds for treating neurodegenerative disorders |
| EP3723859B1 (en) * | 2017-12-11 | 2023-08-30 | Ethnodyne | Compounds for treating neurodegenerative disorders |
| EP3724207A1 (en) * | 2017-12-11 | 2020-10-21 | Ethnodyne | Compounds for treating neurodegenerative disorders |
| CN111377994A (zh) * | 2018-12-28 | 2020-07-07 | 南开大学 | 七种来源于灯笼果的醉茄内酯类化合物及其制备方法和用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110230551A1 (en) | 2008-09-15 | 2011-09-22 | Leslie Gunatilaka | Withaferin a analogs and uses thereof |
| WO2010053655A2 (en) * | 2008-11-07 | 2010-05-14 | University Of Kansas | Therapeutic methods with withaferin a and analogs |
| WO2012106393A2 (en) | 2011-02-01 | 2012-08-09 | University Of Kansas | Withanolide isolated from physalis longifolia and analogs and methods of use thereof |
| US20140120562A1 (en) * | 2011-06-22 | 2014-05-01 | Universite Laval | Methods for the prognostic and/or diagnostic of neurodegenerative disease, methods to identify candidate compounds and compounds for treating neurodegenerative disease |
-
2014
- 2014-11-25 US US15/038,927 patent/US10351590B2/en active Active
- 2014-11-25 EP EP14812105.6A patent/EP3074414B1/en active Active
- 2014-11-25 PL PL14812105T patent/PL3074414T3/pl unknown
- 2014-11-25 MX MX2016006544A patent/MX364528B/es active IP Right Grant
- 2014-11-25 TR TR2019/05218T patent/TR201905218T4/tr unknown
- 2014-11-25 CN CN201480064227.0A patent/CN105940010B/zh active Active
- 2014-11-25 KR KR1020167015115A patent/KR20160137945A/ko not_active Application Discontinuation
- 2014-11-25 ES ES14812105T patent/ES2728870T3/es active Active
- 2014-11-25 AU AU2014352629A patent/AU2014352629B2/en active Active
- 2014-11-25 BR BR112016012002A patent/BR112016012002A2/pt not_active IP Right Cessation
- 2014-11-25 WO PCT/US2014/067436 patent/WO2015077780A1/en active Application Filing
- 2014-11-25 JP JP2016554830A patent/JP6517833B2/ja active Active
- 2014-11-25 CA CA2931064A patent/CA2931064C/en active Active
-
2016
- 2016-05-10 ZA ZA2016/03117A patent/ZA201603117B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112016012002A2 (pt) | 2017-09-19 |
| AU2014352629B2 (en) | 2019-03-28 |
| PL3074414T3 (pl) | 2019-12-31 |
| MX2016006544A (es) | 2016-12-12 |
| CN105940010B (zh) | 2018-03-30 |
| AU2014352629A1 (en) | 2016-05-26 |
| KR20160137945A (ko) | 2016-12-02 |
| US20170022247A1 (en) | 2017-01-26 |
| CN105940010A (zh) | 2016-09-14 |
| ES2728870T3 (es) | 2019-10-29 |
| JP2016537432A (ja) | 2016-12-01 |
| WO2015077780A1 (en) | 2015-05-28 |
| EP3074414B1 (en) | 2019-01-09 |
| JP6517833B2 (ja) | 2019-05-22 |
| CA2931064A1 (en) | 2015-05-28 |
| CA2931064C (en) | 2022-10-18 |
| MX364528B (es) | 2019-04-30 |
| EP3074414A1 (en) | 2016-10-05 |
| US10351590B2 (en) | 2019-07-16 |
| ZA201603117B (en) | 2020-05-27 |
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