PA8469501A1 - Hidroxamidas del acido (4-arilsulfonilamino)-tetrahidropiran-4-carboxilico - Google Patents

Hidroxamidas del acido (4-arilsulfonilamino)-tetrahidropiran-4-carboxilico

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Publication number
PA8469501A1
PA8469501A1 PA19998469501A PA8469501A PA8469501A1 PA 8469501 A1 PA8469501 A1 PA 8469501A1 PA 19998469501 A PA19998469501 A PA 19998469501A PA 8469501 A PA8469501 A PA 8469501A PA 8469501 A1 PA8469501 A1 PA 8469501A1
Authority
PA
Panama
Prior art keywords
disease
aortic aneurysm
burns
treatment
tumor
Prior art date
Application number
PA19998469501A
Other languages
English (en)
Inventor
Lawrence Alan Reiter
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of PA8469501A1 publication Critical patent/PA8469501A1/es

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14—Nitrogen atoms not forming part of a nitro radical

Abstract

LA PRESENTE INVENCION SE REFIERE A UN COMPUESTO DE FORMULA 1 EN LA QUE Q ES COMO SE HA DEFINIDO ANTES, QUE ES UTIL EN EL TRATAMIENTO DE UN TRASTORNO SELECCIONADO DEL GRUPO FORMADO POR ARTRITIS (INCLUYENDO OSTEOARTRITIS Y ARTRITIS REUMATOIDE), ENFERMEDAD INFLAMATORIA DEL INTESTINO, ENFERMEDAD DE CROHN, ENFISEMA, ENFERMEDAD PULMONAR OBSTRUCTIVA CRONICA, ENFERMEDAD DE ALZHEIMER, TOXICIDAD EN EL TRASPLANTE DE UN ORGANO, CAQUEXIA, REACCIONES ALERGICAS, HIPERSENSIBILIDAD POR CONTACTO ALERGICA, CANCER, ULCERACION DE TEJIDOS, REESTENOSIS, ENFERMEDAD PERIODONTAL, EPIDERMOLISIS AMPOLLOSA, OSTEOPOROSIS, FALTA DE FIRMEZA EN IMPLANTES DE ARTICULACIONES ARTIFICIALES, ATEROSCLEROSIS (INCLUYENDO RUPTURA DE LA PLACA ATEROSCLEROTICA), ANEURISMA AORTICO (INCLUYENDO ANEURISMA AORTICO ABDOMINAL Y ANEURISMA AORTICO CEREBRAL), INSUFICIENCIA CARDIACA CONGESTIVA, INFARTO DE MIOCARDIO, ACCIDENTE CEREBROVASCULAR, ISQUEMIA CEREBRAL, TRAUMATISMO CRANEAL, LESION DE LA MEDULA ESPINAL, TRASTORNOS NEURODEGENERATIVOS (AGUDOS Y CRONICOS), TRASTORNOS AUTOINMUNES, ENFERMEDAD DE HUNTINGTON, ENFERMEDAD DE PARKINSON, MIGRAÑA, DEPRESION, NEUROPATIA PERIFERICA, DOLOR, ANGIOPATIA AMILOIDE CEREBRAL, POTENCIACION NOOTROPICA O COGNITIVA, ESCLEROSIS LATERAL AMIOTROFICA, ESCLEROSIS MULTIPLE, ANGIOGENESIS OCULAR, LESION CORNEAL, DEGENERACION MACULAR, CURACION ANOMALA DE HERIDAS, QUEMADURAS, DIABETES, INVASION TUMORAL, CRECIMIENTO DE TUMOR, METASTASIS TUMORAL, QUEMADURAS CORNEALES, ESCLERITIS, SIDA, SEPTICEMIA Y CHOQUE SEPTICO. ADEMAS, LOS COMPUESTOS DE LA PRESENTE INVENCION SE PUEDEN USAR EN TERAPIA DE COMBINACION CON FARMACOS ANTIINFLAMATORIOS NO ESTEROIDEOS (AINE) Y ANALGESICOS CONVENCIONALES, Y EN COMBINACION CON FARMACOS CITOTOXICOS COMO ADRIAMICINA, DAUNOMICINA, CIS-PLATINO, ETOPOSIDO, TAXOL, TAXOTERO Y OTROS ALCALOIDES COMO VINCRISTINA, EN EL TRATAMIENTO DEL CANCER.
PA19998469501A 1998-04-10 1999-03-19 Hidroxamidas del acido (4-arilsulfonilamino)-tetrahidropiran-4-carboxilico PA8469501A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8136498P 1998-04-10 1998-04-10

Publications (1)

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PA8469501A1 true PA8469501A1 (es) 2000-09-29

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PA19998469501A PA8469501A1 (es) 1998-04-10 1999-03-19 Hidroxamidas del acido (4-arilsulfonilamino)-tetrahidropiran-4-carboxilico

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Country Link
US (1) US6087392A (es)
EP (1) EP1070058B1 (es)
JP (1) JP3660873B2 (es)
KR (1) KR100430183B1 (es)
CN (1) CN1296481A (es)
AP (1) AP968A (es)
AR (1) AR019263A1 (es)
AT (1) ATE239005T1 (es)
AU (1) AU758701B2 (es)
BG (1) BG104917A (es)
BR (1) BR9909562A (es)
CA (1) CA2327758C (es)
CO (1) CO5050369A1 (es)
CZ (1) CZ20003737A3 (es)
DE (1) DE69907435T2 (es)
DK (1) DK1070058T3 (es)
DZ (1) DZ2753A1 (es)
EA (1) EA004227B1 (es)
ES (1) ES2192397T3 (es)
GT (1) GT199900043A (es)
HR (1) HRP20000648A2 (es)
HU (1) HUP0101613A3 (es)
ID (1) ID26222A (es)
IL (1) IL138637A0 (es)
IS (1) IS5619A (es)
MA (1) MA24832A1 (es)
MY (1) MY132929A (es)
NO (1) NO20005076L (es)
NZ (1) NZ506806A (es)
OA (1) OA11498A (es)
PA (1) PA8469501A1 (es)
PE (1) PE20000414A1 (es)
PL (1) PL343518A1 (es)
PT (1) PT1070058E (es)
SA (1) SA99200091A (es)
SK (1) SK284154B6 (es)
TN (1) TNSN99053A1 (es)
TR (1) TR200002951T2 (es)
UA (1) UA55526C2 (es)
WO (1) WO1999052889A1 (es)
YU (1) YU57500A (es)
ZA (1) ZA992629B (es)

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