AR007856A1 - Compuestos heterociclicos fusionados como inhibidores de proteina tirosina, quinasa, sus metodos de prepraracion, intermediarios, uso en medicina ycomposiciones farmaceuticas que los contienen - Google Patents

Compuestos heterociclicos fusionados como inhibidores de proteina tirosina, quinasa, sus metodos de prepraracion, intermediarios, uso en medicina ycomposiciones farmaceuticas que los contienen

Info

Publication number
AR007856A1
AR007856A1 ARP970103102A ARP970103102A AR007856A1 AR 007856 A1 AR007856 A1 AR 007856A1 AR P970103102 A ARP970103102 A AR P970103102A AR P970103102 A ARP970103102 A AR P970103102A AR 007856 A1 AR007856 A1 AR 007856A1
Authority
AR
Argentina
Prior art keywords
medicine
pharmaceutical compositions
thyrosine
intermediaries
hetero
Prior art date
Application number
ARP970103102A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9614763.2A external-priority patent/GB9614763D0/en
Priority claimed from GBGB9625492.5A external-priority patent/GB9625492D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AR007856A1 publication Critical patent/AR007856A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

Compuestos heteroaromáticos sustituidos, en particular compuestos heteroaromáticos bicíclicos sustituidos en los cuales un anillo es piridina opirimidina de fórmula I, donde X,Y, U, R1, R2, R y A son como se definió en la memoria. Loscom puestos son descriptos así como sus métodos de preparación,composiciones farmacéuticas incluyendo tales compuestos y su uso en medicina, por ejemplo en el tratamiento de cáncer o psoriasis.
ARP970103102A 1996-07-13 1997-07-11 Compuestos heterociclicos fusionados como inhibidores de proteina tirosina, quinasa, sus metodos de prepraracion, intermediarios, uso en medicina ycomposiciones farmaceuticas que los contienen AR007856A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9614763.2A GB9614763D0 (en) 1996-07-13 1996-07-13 Heterocyclic compounds
GBGB9625492.5A GB9625492D0 (en) 1996-12-07 1996-12-07 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
AR007856A1 true AR007856A1 (es) 1999-11-24

Family

ID=26309694

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970103102A AR007856A1 (es) 1996-07-13 1997-07-11 Compuestos heterociclicos fusionados como inhibidores de proteina tirosina, quinasa, sus metodos de prepraracion, intermediarios, uso en medicina ycomposiciones farmaceuticas que los contienen

Country Status (25)

Country Link
US (2) US6174889B1 (es)
EP (2) EP0912570B1 (es)
JP (1) JP2000514445A (es)
KR (1) KR20000023812A (es)
CN (1) CN1230187A (es)
AP (1) AP9901434A0 (es)
AR (1) AR007856A1 (es)
AT (1) ATE249458T1 (es)
AU (1) AU3443997A (es)
BR (1) BR9710359A (es)
CA (1) CA2260061A1 (es)
CZ (1) CZ8999A3 (es)
DE (1) DE69724789T2 (es)
EA (1) EA199900022A1 (es)
ES (1) ES2206729T3 (es)
HR (1) HRP970371A2 (es)
ID (1) ID19403A (es)
IL (1) IL127796A0 (es)
IS (1) IS4939A (es)
NO (1) NO990124L (es)
PE (1) PE91198A1 (es)
PL (1) PL331221A1 (es)
TR (1) TR199900049T2 (es)
WO (1) WO1998002438A1 (es)
YU (1) YU1099A (es)

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