SI1625121T1 - Derivati pirimidina za zdravljenje abnormalne rasti celic - Google Patents
Derivati pirimidina za zdravljenje abnormalne rasti celicInfo
- Publication number
- SI1625121T1 SI1625121T1 SI200331771T SI200331771T SI1625121T1 SI 1625121 T1 SI1625121 T1 SI 1625121T1 SI 200331771 T SI200331771 T SI 200331771T SI 200331771 T SI200331771 T SI 200331771T SI 1625121 T1 SI1625121 T1 SI 1625121T1
- Authority
- SI
- Slovenia
- Prior art keywords
- treatment
- cell growth
- abnormal cell
- pyrimidine derivatives
- pyrimidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43567002P | 2002-12-20 | 2002-12-20 | |
US50074203P | 2003-09-05 | 2003-09-05 | |
EP03778613A EP1625121B1 (en) | 2002-12-20 | 2003-12-08 | Pyrimidine derivatives for the treatment of abnormal cell growth |
PCT/IB2003/005883 WO2004056807A1 (en) | 2002-12-20 | 2003-12-08 | Pyrimidine derivatives for the treatment of abnormal cell growth |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1625121T1 true SI1625121T1 (sl) | 2010-04-30 |
Family
ID=32685406
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200331771T SI1625121T1 (sl) | 2002-12-20 | 2003-12-08 | Derivati pirimidina za zdravljenje abnormalne rasti celic |
Country Status (31)
Country | Link |
---|---|
US (4) | US7109335B2 (sl) |
EP (1) | EP1625121B1 (sl) |
AP (1) | AP2385A (sl) |
AR (1) | AR043682A1 (sl) |
AT (1) | ATE458731T1 (sl) |
AU (2) | AU2003285614B2 (sl) |
CA (1) | CA2529611C (sl) |
CR (2) | CR8266A (sl) |
CY (1) | CY1110069T1 (sl) |
DE (1) | DE60331479D1 (sl) |
DK (1) | DK1625121T3 (sl) |
DO (1) | DOP2003000793A (sl) |
EA (1) | EA013248B1 (sl) |
EC (1) | ECSP066406A (sl) |
ES (1) | ES2338545T3 (sl) |
GE (1) | GEP20084357B (sl) |
IL (1) | IL172047A (sl) |
MX (1) | MXPA06002608A (sl) |
MY (1) | MY142109A (sl) |
NL (1) | NL1025067C2 (sl) |
NZ (1) | NZ543719A (sl) |
OA (1) | OA13309A (sl) |
PA (1) | PA8593001A1 (sl) |
PE (1) | PE20041016A1 (sl) |
PL (1) | PL379330A1 (sl) |
PT (1) | PT1625121E (sl) |
RS (1) | RS20060097A (sl) |
SI (1) | SI1625121T1 (sl) |
TN (1) | TNSN06074A1 (sl) |
TW (1) | TWI283673B (sl) |
WO (1) | WO2004056807A1 (sl) |
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PL379330A1 (pl) | 2002-12-20 | 2006-08-21 | Pfizer Products Inc. | Pochodne pirymidyny dla leczenia nienormalnego wzrostu komórek |
US7109337B2 (en) | 2002-12-20 | 2006-09-19 | Pfizer Inc | Pyrimidine derivatives for the treatment of abnormal cell growth |
DE10349423A1 (de) * | 2003-10-16 | 2005-06-16 | Schering Ag | Sulfoximinsubstituierte Parimidine als CDK- und/oder VEGF-Inhibitoren, deren Herstellung und Verwendung als Arzneimittel |
CA2566332A1 (en) | 2004-05-14 | 2005-11-24 | Pfizer Products Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
JP2007537235A (ja) * | 2004-05-14 | 2007-12-20 | ファイザー・プロダクツ・インク | 異常細胞増殖の治療用ピリミジン誘導体 |
GEP20104875B (en) * | 2004-05-14 | 2010-01-11 | Pfizer Prod Inc | Pyrimidine derivatives for the treatment of abnormal cell growth |
US20060205945A1 (en) * | 2004-05-14 | 2006-09-14 | Pfizer Inc | Pyrimidine derivatives for the treatment of abnormal cell growth |
EP1758887A1 (en) | 2004-05-14 | 2007-03-07 | Pfizer Products Incorporated | Pyrimidine derivatives for the treatment of abnormal cell growth |
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EP1765461A1 (en) * | 2004-06-21 | 2007-03-28 | Pharmacia & Upjohn Company LLC | Pyk2 inhibitors for stimulation of osteoblast function |
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EP1966192B1 (en) * | 2005-12-01 | 2012-10-17 | Pfizer Products Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
JP5161233B2 (ja) | 2006-10-19 | 2013-03-13 | ライジェル ファーマシューティカルズ, インコーポレイテッド | 自己免疫疾患の処置のためのjakキナーゼの阻害剤としての2,4−ピリミジンアミン誘導体 |
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EA200901249A1 (ru) * | 2007-03-16 | 2010-04-30 | Юниверсити Оф Флорида Ресерч Фаундэйшн, Инк. | Ингибиторы связывания протеинкиназ |
EP2146779B1 (en) | 2007-04-18 | 2016-08-10 | Pfizer Products Inc. | Sulfonyl amide derivatives for the treatment of abnormal cell growth |
KR101294731B1 (ko) * | 2007-06-04 | 2013-08-16 | 삼성디스플레이 주식회사 | 어레이 기판, 이를 갖는 표시패널 및 이의 제조방법 |
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US20120244141A1 (en) | 2010-09-28 | 2012-09-27 | Boehringer Ingelheim International Gmbh | Stratification of cancer patients for susceptibility to therapy with PTK2 inhibitors |
PT2646448T (pt) | 2010-11-29 | 2017-10-04 | Osi Pharmaceuticals Llc | Inibidores macrocíclicos de cinases |
JP5937111B2 (ja) | 2011-02-17 | 2016-06-22 | カンサー・セラピューティクス・シーアールシー・プロプライエタリー・リミテッドCancer Therapeutics Crc Pty Limited | Fak阻害剤 |
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UA80767C2 (en) | 2002-12-20 | 2007-10-25 | Pfizer Prod Inc | Pyrimidine derivatives for the treatment of abnormal cell growth |
DK1663991T3 (da) * | 2003-09-05 | 2007-04-10 | Pfizer Prod Inc | Selektiv syntese af CF3-substituerede pyrimidiner |
EP1758887A1 (en) * | 2004-05-14 | 2007-03-07 | Pfizer Products Incorporated | Pyrimidine derivatives for the treatment of abnormal cell growth |
CA2566332A1 (en) * | 2004-05-14 | 2005-11-24 | Pfizer Products Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
JP2007537235A (ja) * | 2004-05-14 | 2007-12-20 | ファイザー・プロダクツ・インク | 異常細胞増殖の治療用ピリミジン誘導体 |
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2003
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- 2003-12-08 AP AP2005003438A patent/AP2385A/xx active
- 2003-12-08 EA EA200600122A patent/EA013248B1/ru not_active IP Right Cessation
- 2003-12-08 AU AU2003285614A patent/AU2003285614B2/en not_active Expired
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- 2003-12-08 WO PCT/IB2003/005883 patent/WO2004056807A1/en active Application Filing
- 2003-12-08 PT PT03778613T patent/PT1625121E/pt unknown
- 2003-12-08 SI SI200331771T patent/SI1625121T1/sl unknown
- 2003-12-08 RS YUP-2006/0097A patent/RS20060097A/sr unknown
- 2003-12-08 CA CA002529611A patent/CA2529611C/en not_active Expired - Lifetime
- 2003-12-08 AT AT03778613T patent/ATE458731T1/de active
- 2003-12-08 DK DK03778613.4T patent/DK1625121T3/da active
- 2003-12-08 ES ES03778613T patent/ES2338545T3/es not_active Expired - Lifetime
- 2003-12-08 DE DE60331479T patent/DE60331479D1/de not_active Expired - Lifetime
- 2003-12-08 EP EP03778613A patent/EP1625121B1/en not_active Expired - Lifetime
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2004
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2005
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2006
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- 2006-03-03 EC EC2006006406A patent/ECSP066406A/es unknown
- 2006-03-03 TN TNP2006000074A patent/TNSN06074A1/en unknown
- 2006-08-17 US US11/506,689 patent/US7351712B2/en not_active Expired - Lifetime
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2008
- 2008-03-31 US US12/059,889 patent/US7674796B2/en not_active Expired - Lifetime
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2009
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2010
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2011
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