CO4940418A1
(es)
*
|
1997-07-18 |
2000-07-24 |
Novartis Ag |
Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
|
USRE43932E1
(en)
|
1997-07-18 |
2013-01-15 |
Novartis Ag |
Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use
|
ITMI992711A1
(it)
*
|
1999-12-27 |
2001-06-27 |
Novartis Ag |
Composti organici
|
US7087608B2
(en)
*
|
2000-03-03 |
2006-08-08 |
Robert Charles Atkins |
Use of PDGF receptor tyrosine kinase inhibitors for the treatment of diabetic nephropathy
|
WO2002034727A2
(en)
*
|
2000-10-27 |
2002-05-02 |
Novartis Ag |
Treatment of gastrointestinal stromal tumors
|
PT3351246T
(pt)
|
2001-02-19 |
2019-06-07 |
Novartis Pharma Ag |
Derivado de rapamicina para o tratamento de um tumor sólido associado a angiogenese desregulada
|
WO2002067941A2
(en)
|
2001-02-27 |
2002-09-06 |
Novartis Ag |
Combination comprising a signal transduction inhibitor and an epothilone derivative
|
GB0108606D0
(en)
*
|
2001-04-05 |
2001-05-23 |
Novartis Ag |
Organic compounds
|
EP1704863A3
(en)
*
|
2001-05-16 |
2010-11-24 |
Novartis AG |
Combination comprising N-5-4-(4-Methyl-Piperazino-Methyl-)Benzoyla Mido]-2-Methylphenyl -4-(3-Pyridyl)-2Phyrimidine-amine and a chemotherapeutic agent
|
AU2005246965B2
(en)
*
|
2001-05-16 |
2008-04-17 |
Novartis Ag |
Combination comprising N-{5-[4(4-methyl-piperazino-methyl)-bezoylamido]-2-methylphenyl}-4-(3-pyridyl)-2pyrimidine-amine and a chemotherapeutic agent
|
PL392652A1
(pl)
|
2001-05-16 |
2010-12-06 |
Novartis Ag |
Kombinacja zawierająca N-{5-[4-(4-metylo-piperazyno-metylo)-benzoiloamido]-2-metylofenylo}-4-(3-pirydylo)-2-pirymidyno-aminę oraz środek chemoterapeutyczny, jej zastosowanie, kompozycja farmaceutyczna ją zawierająca oraz zestaw zawierający taką kombinację
|
WO2002102976A2
(en)
|
2001-06-14 |
2002-12-27 |
The Regents Of The University Of California |
Mutations in the bcr-abl tyrosine kinase associated with resistance to sti-571
|
WO2003000186A2
(en)
|
2001-06-21 |
2003-01-03 |
Ariad Pharmaceuticals, Inc. |
Novel phenylamino-pyrimidines and uses thereof
|
JP2004537542A
(ja)
|
2001-06-29 |
2004-12-16 |
アブ サイエンス |
炎症性腸疾患(ibd)を治療するための、チロシンキナーゼ阻害剤の使用
|
EP1401413B1
(en)
|
2001-06-29 |
2006-11-22 |
AB Science |
Use of tyrosine kinase inhibitions for treating allergic diseases
|
JP2005500041A
(ja)
|
2001-06-29 |
2005-01-06 |
アブ サイエンス |
強力で選択的かつ非毒性のc−kit阻害剤
|
DE60212627T2
(de)
|
2001-06-29 |
2007-06-14 |
Ab Science |
Verwendung von Tyrosinkinase-Inhibitoren zur Behandlung von entzündlichen Krankheiten
|
CN1523991A
(zh)
|
2001-08-10 |
2004-08-25 |
��˹��ŵ�� |
单独的c-Src抑制剂或其与STI571的组合用于治疗白血病的用途
|
GB0120690D0
(en)
|
2001-08-24 |
2001-10-17 |
Novartis Ag |
Organic compounds
|
WO2003039550A1
(en)
*
|
2001-09-20 |
2003-05-15 |
Ab Science |
Use of tyrosine kinase inhibitors for whitening human skin and treating melanocyte dysfunction associated diseases
|
EP2343365A1
(en)
|
2001-10-05 |
2011-07-13 |
Novartis AG |
Mutated Abl kinase domains
|
US7045523B2
(en)
|
2001-10-18 |
2006-05-16 |
Novartis Ag |
Combination comprising N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine and telomerase inhibitor
|
NZ532593A
(en)
*
|
2001-10-25 |
2007-11-30 |
Wisconsin Alumni Res Found |
Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and method of using same
|
GB0127922D0
(en)
*
|
2001-11-21 |
2002-01-16 |
Novartis Ag |
Organic compounds
|
GB0201508D0
(en)
|
2002-01-23 |
2002-03-13 |
Novartis Ag |
Organic compounds
|
GB0201882D0
(en)
|
2002-01-28 |
2002-03-13 |
Novartis Ag |
Organic compounds
|
AU2007201056B2
(en)
*
|
2002-01-28 |
2010-06-10 |
Hyks-Instituutti Oy |
Treatment of rheumatoid arthritis using imatinib
|
GB0202873D0
(en)
*
|
2002-02-07 |
2002-03-27 |
Novartis Ag |
Organic compounds
|
DE60305460D1
(de)
*
|
2002-02-22 |
2006-06-29 |
Us Government |
Verwendung von 4-(4-methylpiperazin-1-ylmethyl)-n 4-methyl-3-(4-pyridin-3-yl) pyrimidin-2-ylamino) phenyl benzamid zur behandlung von seminomen
|
BR0308053A
(pt)
*
|
2002-02-28 |
2004-12-28 |
Novartis Ag |
Stents revestidos com n-{5-[4-(4-metil-piperazino-metil)-benzoilamido]-2-metil fenil}-4-(3-piridil)-2-pirimidina-amina
|
AU2003233946A1
(en)
*
|
2002-03-15 |
2003-09-29 |
Novartis Ag |
4-(4-methylpiperazin-1-ylmethyl)-n-(4-methyl-3(4-pyridin-3-yl)pyrimidin-2-yl-amino)phenyl)-benzamide for treating ang ii-mediated diseases
|
GB0206215D0
(en)
|
2002-03-15 |
2002-05-01 |
Novartis Ag |
Organic compounds
|
CA2479257A1
(en)
*
|
2002-03-21 |
2003-10-02 |
Dana-Farber Cancer Institute, Inc. |
Inhibition of cell death responses induced by oxidative stress
|
AU2003216573A1
(en)
*
|
2002-04-16 |
2003-10-27 |
Issam Moussa |
Drug eluting vascular stent and method of treating hyperproliferative vascular disease
|
AU2007201830C1
(en)
*
|
2002-04-23 |
2017-09-07 |
Novartis Pharma Ag |
High drug load tablet
|
GB0209265D0
(en)
*
|
2002-04-23 |
2002-06-05 |
Novartis Ag |
Organic compounds
|
EP1944026B1
(en)
|
2002-05-16 |
2013-06-26 |
Novartis AG |
Use of EDG receptor binding agents in cancer
|
WO2004026930A2
(en)
*
|
2002-06-26 |
2004-04-01 |
The Ohio State University Research Foundation |
The method for reducing inflammation using sti-571 or its salt
|
BRPI0312288B8
(pt)
|
2002-06-28 |
2021-05-25 |
Nippon Shinyaku Co Ltd |
derivados de amidas
|
WO2004002489A1
(en)
*
|
2002-06-28 |
2004-01-08 |
The Administrators Of The Tulane Educational Fund |
4-(4-methylpiperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide for treating pulmonary fibrosis
|
EP1523345A1
(en)
*
|
2002-07-18 |
2005-04-20 |
Medtronic AVE Inc. |
Medical devices comprising a protein-tyrosine kinase inhibitor to inhibit restonosis
|
CA2492878A1
(en)
*
|
2002-07-19 |
2004-01-29 |
Ludwig Institute For Cancer Research |
Enhancing the effect of radioimmunotherapy in the treatment of tumors
|
BR0312873A
(pt)
*
|
2002-07-24 |
2005-06-28 |
Univ Cincinnati |
4-(4-metilpiperazin-1-ilmetil)-n-[4-metil-3-(4-piridin-3-il) pirimidin-2-ilamino)fenil] benzamida para tratamento de doenças associadas com ret cinase mutante
|
AU2003232376A1
(en)
*
|
2002-07-24 |
2004-02-09 |
Novartis Ag |
4-(4-methylpiperazin-1-ylmethyl)-n-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl)-benzamide for treating anaplastic thyroid cancer
|
AU2003250701A1
(en)
*
|
2002-07-31 |
2004-02-16 |
Wayne R. Danter |
Protein tyrosine kinase inhibitors
|
BRPI0313165B8
(pt)
|
2002-08-02 |
2021-05-25 |
Ab Science |
2-(3-aminoaril)amino-4-aril-tiazóis e sua utilização como inibidores de c-kit
|
US8450302B2
(en)
|
2002-08-02 |
2013-05-28 |
Ab Science |
2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors
|
CA2439440A1
(en)
|
2002-09-05 |
2004-03-05 |
Emory University |
Treatment of tuberous sclerosis associated neoplasms
|
DE60318089T2
(de)
*
|
2002-10-09 |
2008-12-04 |
Critical Outcome Technologies, Inc. |
Protein-tyrosine-kinase-inhibitoren
|
GB0224455D0
(en)
*
|
2002-10-21 |
2002-11-27 |
Novartis Ag |
Organic compounds
|
US20060154936A1
(en)
*
|
2002-10-25 |
2006-07-13 |
Lasky Joseph A |
Use of n-'5-'4-(4-methylpiperaziomethyl)-benzoylamido!-2-methylphenyl!-4-(3-pyridyl)2-pyridine-amine for the treatment of pulmonary hypertension
|
US7094785B1
(en)
|
2002-12-18 |
2006-08-22 |
Cornell Research Foundation, Inc. |
Method of treating polycythemia vera
|
GB2398565A
(en)
*
|
2003-02-18 |
2004-08-25 |
Cipla Ltd |
Imatinib preparation and salts
|
BR0318237A
(pt)
*
|
2003-04-04 |
2006-04-04 |
Bayco Tech Ltd |
sonda vascular
|
AU2003232650A1
(en)
|
2003-05-06 |
2004-11-26 |
Il Yang Pharm Co., Ltd. |
N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof
|
MY150088A
(en)
|
2003-05-19 |
2013-11-29 |
Irm Llc |
Immunosuppressant compounds and compositions
|
CA2524048C
(en)
|
2003-05-19 |
2013-06-25 |
Irm Llc |
Immunosuppressant compounds and compositions
|
WO2004105763A2
(en)
*
|
2003-05-27 |
2004-12-09 |
Haegerkvist Robert Per |
Use of tyrosine kinase inhibitor to treat diabetes
|
GB0312086D0
(en)
*
|
2003-05-27 |
2003-07-02 |
Novartis Ag |
Organic compounds
|
TR200504337T1
(tr)
*
|
2003-06-02 |
2006-12-21 |
Hetero Drugs Limited |
Imatinib mezilat'ın yeni polimorfları
|
US20060240014A1
(en)
*
|
2003-06-03 |
2006-10-26 |
Beth Israel Deaconess Medical Center |
Methods and compounds for the treatment of vascular stenosis
|
BRPI0414527A
(pt)
*
|
2003-09-19 |
2006-11-07 |
Novartis Ag |
tratamento de tumores estromáticos gastrointestinais com imatinib e midostaurina
|
JP4971797B2
(ja)
|
2003-10-23 |
2012-07-11 |
アブ サイエンス |
チロシンキナーゼ阻害薬としての2−アミノアリールオキサゾール化合物
|
ES2324917T3
(es)
|
2003-11-18 |
2009-08-19 |
Novartis Ag |
Inhibidores de la forma mutante de kit.
|
WO2005063720A1
(ja)
*
|
2003-12-25 |
2005-07-14 |
Nippon Shinyaku Co., Ltd. |
アミド誘導体及び医薬
|
PE20051096A1
(es)
|
2004-02-04 |
2006-01-23 |
Novartis Ag |
Formas de sal de 4-(4-metilpiperazin-1-ilmetil)-n-[4-metil-3-(4-piridin-3-il)pirimidin-2-ilamino)fenil]-benzamida
|
PL1720853T3
(pl)
*
|
2004-02-11 |
2016-06-30 |
Natco Pharma Ltd |
Nowa odmiana polimorficzna metanosulfonianu imatynibu i sposób jej otrzymywania
|
CN1309719C
(zh)
*
|
2004-02-18 |
2007-04-11 |
陈国庆 |
苯氨基嘧啶衍生物及其用途
|
UA84462C2
(ru)
|
2004-04-02 |
2008-10-27 |
Институт Фармацевтични |
Полиморфные модификации кислотно-аддитивных солей иматиниба с метансульфоновой кислотой
|
DK2253614T3
(da)
|
2004-04-07 |
2013-01-07 |
Novartis Ag |
IAP-inhibitorer
|
GB0512324D0
(en)
|
2005-06-16 |
2005-07-27 |
Novartis Ag |
Organic compounds
|
KR20070055431A
(ko)
*
|
2004-07-01 |
2007-05-30 |
더 네덜란즈 캔서 인스티튜트 |
Bcrp 억제제 및4-(4-메틸피페라진-1-일메틸)-n-[4-메틸-3-(4-피리딘-3-일)피리미딘-2-일아미노)페닐]-벤즈아미드를 포함하는 조합물
|
KR101348625B1
(ko)
|
2004-09-02 |
2014-01-07 |
씨아이피엘에이 엘티디. |
이매티닙 메실레이트의 안정한 결정형 및 그의 제조방법
|
AP2470A
(en)
|
2004-09-09 |
2012-09-17 |
Natco Pharma Ltd |
Novel phenylaminopyrimidine derivatives as inhibitors of BCR-ABL kinase
|
US8735415B2
(en)
|
2004-09-09 |
2014-05-27 |
Natco Pharma Limited |
Acid addition salts of (3,5-Bis trifluoromethyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide
|
WO2006048890A1
(en)
*
|
2004-11-04 |
2006-05-11 |
Sun Pharmaceutical Industries Limited |
Imatinib mesylate crystal form and process for preparation thereof
|
WO2006054314A1
(en)
*
|
2004-11-17 |
2006-05-26 |
Natco Pharma Limited |
Polymorphic forms of imatinib mesylate
|
JP5197016B2
(ja)
|
2004-12-23 |
2013-05-15 |
デシファラ ファーマスーティカルズ, エルエルシー |
酵素モジュレータ及び治療
|
MX2007012392A
(es)
|
2005-04-04 |
2007-12-05 |
Ab Science |
Derivados de oxazol sustituidos y su uso como inhibidores de tirosina cinasa.
|
CN103638028A
(zh)
|
2005-05-02 |
2014-03-19 |
诺瓦提斯公司 |
嘧啶基氨基苯甲酰胺衍生物用于治疗全身性肥大细胞增多症的应用
|
GB0510390D0
(en)
|
2005-05-20 |
2005-06-29 |
Novartis Ag |
Organic compounds
|
PT1893213E
(pt)
|
2005-06-03 |
2010-04-19 |
Novartis Ag |
Combinação de compostos pirimidilaminobenzamida e imatinib para tratamento ou prevenção de doenças proliferativas
|
GT200600316A
(es)
*
|
2005-07-20 |
2007-04-02 |
|
Sales de 4-metilo-n-(3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo)-3-(4-piridina-3-ilo-pirimidina-2-iloamino)- benzamida.
|
KR100674813B1
(ko)
|
2005-08-05 |
2007-01-29 |
일양약품주식회사 |
N-페닐-2-피리미딘-아민 유도체 및 그의 제조방법
|
DE502006005084D1
(de)
*
|
2005-08-15 |
2009-11-26 |
Siegfried Generics Int Ag |
Filmtablette oder Granulat enthaltend ein Pyridylpyrimidin
|
EP1922314A1
(en)
*
|
2005-08-26 |
2008-05-21 |
Novartis AG |
Delta and epsilon crystal forms of imatinib mesylate
|
CA2629245C
(en)
|
2005-11-21 |
2016-07-12 |
Novartis Ag |
Neuroendocrine tumor treatment
|
US7893076B2
(en)
*
|
2005-11-25 |
2011-02-22 |
Novartis Ag |
Crystalline form F of Imatinib mesylate
|
GB0605120D0
(en)
|
2006-03-14 |
2006-04-26 |
Novartis Ag |
Organic Compounds
|
EP2606890A1
(en)
|
2006-04-05 |
2013-06-26 |
Novartis AG |
Combinations comprising BCR-ABL/C-KIT/PDGF-R TK inhibitors for treating cancer
|
CN101415409B
(zh)
|
2006-04-05 |
2012-12-05 |
诺瓦提斯公司 |
用于治疗癌症的治疗剂的组合
|
US7977348B2
(en)
|
2006-04-27 |
2011-07-12 |
Sicor Inc. |
Polymorphic forms of imatinib mesylate and processes for preparation of novel crystalline forms as well as amorphous and form α
|
BRPI0702877A2
(pt)
|
2006-04-27 |
2015-07-07 |
Ivax Pharmaceuticals S R O E Teva Pharmaceutical Usa Inc |
Formas polimórficas de mesilato de imatinib, processo para o novo preparo de novas formas cristalinas, amorfas e forma alfa, composições farmacêuticas correlatas, seus processos de preparo e uso
|
US8067421B2
(en)
|
2006-04-27 |
2011-11-29 |
Sicor Inc. |
Polymorphic forms of imatinib mesylate and processes for preparation of novel crystalline forms as well as amorphous and form α
|
US20060223816A1
(en)
*
|
2006-05-08 |
2006-10-05 |
Chemagis Ltd. |
Imatinib mesylate alpha form and production process therefor
|
CN101443002B
(zh)
|
2006-05-09 |
2012-03-21 |
诺瓦提斯公司 |
包含铁螯合剂和抗肿瘤药的组合及其用途
|
US20060223817A1
(en)
*
|
2006-05-15 |
2006-10-05 |
Chemagis Ltd. |
Crystalline imatinib base and production process therefor
|
WO2008004944A1
(en)
*
|
2006-07-04 |
2008-01-10 |
Astrazeneca Ab |
Novel crystalline form ii
|
WO2008004945A1
(en)
*
|
2006-07-04 |
2008-01-10 |
Astrazeneca Ab |
Novel crystalline forms i and ii
|
US8246966B2
(en)
|
2006-08-07 |
2012-08-21 |
University Of Georgia Research Foundation, Inc. |
Trypanosome microsome system and uses thereof
|
WO2008027600A2
(en)
*
|
2006-09-01 |
2008-03-06 |
Teva Pharmaceutical Industries Ltd. |
Imatinib compositions
|
EP2251042A3
(en)
|
2006-09-22 |
2012-05-02 |
Novartis AG |
Method of optimizing the treatment of philadelphia-positive leukemia with abl tyrosine kinase inhibitors
|
WO2008037477A1
(en)
|
2006-09-29 |
2008-04-03 |
Novartis Ag |
Pyrazolopyrimidines as p13k lipid kinase inhibitors
|
EP1988089A1
(en)
|
2006-10-26 |
2008-11-05 |
Sicor, Inc. |
Imatinib base, and imatinib mesylate and processes for preparation thereof
|
US20080103305A1
(en)
*
|
2006-10-26 |
2008-05-01 |
Macdonald Peter |
Process for the preparation of imatinib
|
US8466154B2
(en)
|
2006-10-27 |
2013-06-18 |
The Board Of Regents Of The University Of Texas System |
Methods and compositions related to wrapping of dehydrons
|
MX2009004861A
(es)
*
|
2006-11-09 |
2009-05-21 |
Abbott Gmbh & Co Kg |
Forma de dosificacion farmaceutica para la administracion oral de inhibidor de tirosina quinasa.
|
EP1920767A1
(en)
*
|
2006-11-09 |
2008-05-14 |
Abbott GmbH & Co. KG |
Melt-processed imatinib dosage form
|
CA2669531A1
(en)
|
2006-11-22 |
2008-06-05 |
University Of Georgia Research Foundation, Inc. |
Tyrosine kinase inhibitors as anti-kinetolastid and anti-apicomplexan agents
|
US8034815B2
(en)
|
2007-01-11 |
2011-10-11 |
Critical Outcome Technologies, Inc. |
Compounds and method for treatment of cancer
|
EP2125895B1
(en)
|
2007-02-02 |
2015-04-08 |
Vegenics Pty Ltd |
Vegf receptor antagonists for treating organ transplant alloimmunity and arteriosclerosis
|
KR100799821B1
(ko)
*
|
2007-02-05 |
2008-01-31 |
동화약품공업주식회사 |
신규한 이마티닙 캠실레이트 및 그의 제조방법
|
ES2522169T3
(es)
*
|
2007-02-13 |
2014-11-13 |
Ab Science |
Forma polimorfa de derivado de 2-amino (nitroaril) tiazol
|
CN101626758A
(zh)
|
2007-02-15 |
2010-01-13 |
诺瓦提斯公司 |
用于治疗癌症的lbh589和其他治疗剂的组合
|
CN101323629B
(zh)
*
|
2007-02-16 |
2011-08-17 |
江苏正大天晴药业股份有限公司 |
4-{6-[5-(2-氯-6-甲基苯胺甲酰基)-噻唑-2-氨基]-2-甲基嘧啶-4}-哌嗪-1-甲基磷酸二乙酯
|
BRPI0808840A2
(pt)
*
|
2007-03-12 |
2014-09-02 |
Reddy S Laborartories Ltd Dr |
Mesilato de imatinib
|
US20080234286A1
(en)
*
|
2007-03-20 |
2008-09-25 |
Chemagis Ltd. |
Stable amorphous imatinib mesylate and production process therefor
|
US7550591B2
(en)
*
|
2007-05-02 |
2009-06-23 |
Chemagis Ltd. |
Imatinib production process
|
WO2008136010A1
(en)
*
|
2007-05-07 |
2008-11-13 |
Natco Pharma Limited |
A process for the preparation of highly pure imatinib base
|
WO2008150481A2
(en)
*
|
2007-05-29 |
2008-12-11 |
Sicor Inc. |
Processes for the preparation of crystalline form beta of imatinib mesylate
|
EP2305263B1
(en)
|
2007-06-07 |
2012-09-19 |
Novartis AG |
Stabilized amorphous forms of imatinib mesylate
|
US20090087489A1
(en)
*
|
2007-09-25 |
2009-04-02 |
Bella Gerber |
Imatinib compositions
|
US20090082361A1
(en)
*
|
2007-09-26 |
2009-03-26 |
Protia, Llc |
Deuterium-enriched imatinib
|
WO2009048947A1
(en)
*
|
2007-10-09 |
2009-04-16 |
Board Of Regents, The University Of Texas System |
Methods of treatment of opioid tolerance, physical dependence, pain, and addiction with inhibitors of certain growth factor receptors
|
CA2710039C
(en)
|
2007-12-26 |
2018-07-03 |
Critical Outcome Technologies, Inc. |
Semicarbazones, thiosemicarbazones and related compounds and methods for treatment of cancer
|
MX2010010525A
(es)
|
2008-03-24 |
2010-10-25 |
Novartis Ag |
Inhibidores de metaloproteasa de matriz basados en aril-sulfonamida.
|
EP2260020B1
(en)
|
2008-03-26 |
2014-07-23 |
Novartis AG |
Hydroxamate-based inhibitors of deacetylases b
|
CA2723961C
(en)
|
2008-05-21 |
2017-03-21 |
Ariad Pharmaceuticals, Inc. |
Phosphorous derivatives as kinase inhibitors
|
US9273077B2
(en)
|
2008-05-21 |
2016-03-01 |
Ariad Pharmaceuticals, Inc. |
Phosphorus derivatives as kinase inhibitors
|
CN101584696A
(zh)
|
2008-05-21 |
2009-11-25 |
上海艾力斯医药科技有限公司 |
包含喹唑啉衍生物的组合物及制备方法、用途
|
CA2727737C
(en)
|
2008-06-27 |
2016-08-23 |
Indiana University Research And Technology Corporation |
Materials and methods for suppressing and/or treating neurofibroma and related tumors
|
DE102008031037A1
(de)
|
2008-06-30 |
2009-12-31 |
Dömling, Alexander, Priv.-Doz. Dr. |
Gleevec zur Anwedung in der Organtransplantation
|
CA2730890C
(en)
|
2008-07-17 |
2018-05-15 |
Critical Outcome Technologies Inc. |
Thiosemicarbazone inhibitor compounds and cancer treatment methods
|
WO2010019557A1
(en)
*
|
2008-08-12 |
2010-02-18 |
Concert Pharmaceuticals Inc. |
N-phenyl-2-pyrimidineamine derivatives
|
US20200155558A1
(en)
|
2018-11-20 |
2020-05-21 |
Boehringer Ingelheim International Gmbh |
Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
|
EP2344161B1
(en)
|
2008-10-16 |
2018-12-19 |
Celator Pharmaceuticals, Inc. |
Combinations of a liposomal water-soluble camptothecin with cetuximab or bevacizumab
|
EP2186514B1
(en)
|
2008-11-14 |
2016-06-29 |
Kinki University |
Treatment of Malignant Peripheral Nerve Sheath Tumors
|
WO2010065433A1
(en)
|
2008-12-01 |
2010-06-10 |
Novartis Ag |
Method of optimizing the treatment of philadelphia-positive leukemia with imatinib mesylate
|
MX2011006622A
(es)
|
2008-12-18 |
2011-07-12 |
Novartis Ag |
Sales novedosas.
|
JP2012512884A
(ja)
|
2008-12-18 |
2012-06-07 |
ノバルティス アーゲー |
1−(4−{1−[(e)−4−シクロヘキシル−3−トリフルオロメチル−ベンジルオキシイミノ]−エチル}−2−エチル−ベンジル)−アゼチジン−3−カルボン酸の新規の多形相
|
DK2676953T3
(en)
|
2008-12-18 |
2017-07-03 |
Novartis Ag |
Hemifumarate salt of 1- [4- [1- (4-cyclohexyl-3-trifluoromethyl-benzyloxyimino) -ethyl] -2-ethyl-benzyl] -acetidine-3-carboxylic acid for use in the treatment of lymphocyte-mediated diseases
|
WO2010083617A1
(en)
|
2009-01-21 |
2010-07-29 |
Oncalis Ag |
Pyrazolopyrimidines as protein kinase inhibitors
|
DK2391366T3
(da)
|
2009-01-29 |
2013-01-07 |
Novartis Ag |
Substituerede benzimidazoler til behandling af astrocytomer
|
UA103918C2
(en)
|
2009-03-02 |
2013-12-10 |
Айерем Элелси |
N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as wnt signaling modulators
|
US8530492B2
(en)
|
2009-04-17 |
2013-09-10 |
Nektar Therapeutics |
Oligomer-protein tyrosine kinase inhibitor conjugates
|
SG10201501131SA
(en)
|
2009-04-28 |
2015-04-29 |
Daiichi Sankyo Co Ltd |
Novel solvate crystals
|
US20100330130A1
(en)
|
2009-05-22 |
2010-12-30 |
Actavis Group Ptc Ehf |
Substantially pure imatinib or a pharmaceutically acceptable salt thereof
|
TW201102068A
(en)
*
|
2009-06-02 |
2011-01-16 |
Novartis Ag |
Treatment of ophthalmologic disorders mediated by alpha-carbonic anhydrase isoforms
|
DK2445903T3
(da)
|
2009-06-26 |
2014-06-23 |
Novartis Ag |
1,3-Disubstituerede imidazolidin-2-on-derivater som CYP17-inhibitorer
|
US8389526B2
(en)
|
2009-08-07 |
2013-03-05 |
Novartis Ag |
3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
|
AU2010283806A1
(en)
|
2009-08-12 |
2012-03-01 |
Novartis Ag |
Heterocyclic hydrazone compounds and their uses to treat cancer and inflammation
|
JP5819831B2
(ja)
|
2009-08-17 |
2015-11-24 |
インテリカイン, エルエルシー |
複素環式化合物およびそれらの使用
|
KR20120089463A
(ko)
|
2009-08-20 |
2012-08-10 |
노파르티스 아게 |
헤테로시클릭 옥심 화합물
|
IN2012DN01693A
(no)
|
2009-08-26 |
2015-06-05 |
Novartis Ag |
|
CZ2009570A3
(cs)
|
2009-08-26 |
2011-03-09 |
Zentiva, K. S. |
Príprava, stabilizace a využití polymorfu imatinib mesylátu pro vývoj lékových forem
|
CN102596963A
(zh)
|
2009-09-10 |
2012-07-18 |
诺瓦提斯公司 |
二环杂芳基的醚衍生物
|
WO2011039782A1
(en)
*
|
2009-09-29 |
2011-04-07 |
Ind-Swift Laboratories Limited |
Processes for preparing imatinib and pharmaceutically acceptable salts thereof
|
PL389357A1
(pl)
|
2009-10-22 |
2011-04-26 |
Tomasz Koźluk |
Sole imatinibu z pochodnymi kwasów winowych i sposób ich wytwarzania
|
BR112012010519A2
(pt)
|
2009-11-04 |
2017-12-05 |
Novartis Ag |
derivados de sulfonamida heterocíclicos
|
CN102781237A
(zh)
|
2009-11-23 |
2012-11-14 |
天蓝制药公司 |
用于传递治疗剂的基于环糊精的聚合物
|
JP2013512215A
(ja)
|
2009-11-25 |
2013-04-11 |
ノバルティス アーゲー |
二環式ヘテロアリールのベンゼン縮合6員酸素含有ヘテロ環誘導体
|
EA201200823A1
(ru)
|
2009-12-08 |
2013-02-28 |
Новартис Аг |
Гетероциклические производные сульфонамидов
|
CU24130B1
(es)
|
2009-12-22 |
2015-09-29 |
Novartis Ag |
Isoquinolinonas y quinazolinonas sustituidas
|
US8440693B2
(en)
|
2009-12-22 |
2013-05-14 |
Novartis Ag |
Substituted isoquinolinones and quinazolinones
|
US20110178287A1
(en)
|
2010-01-19 |
2011-07-21 |
Cerulean Pharma Inc. |
Cyclodextrin-based polymers for therapeutic delivery
|
WO2011095835A1
(en)
|
2010-02-02 |
2011-08-11 |
Actavis Group Ptc Ehf |
Highly pure imatinib or a pharmaceutically acceptable salt thereof
|
CA2789989A1
(en)
|
2010-02-15 |
2011-08-18 |
Reliance Life Sciences Pvt. Ltd. |
Process for the preparation of alpha form of imatinib mesylate
|
PL390611A1
(pl)
|
2010-03-04 |
2011-09-12 |
Tomasz Koźluk |
Sposób otrzymywania polimorficznej formy alfa i nowa forma polimorficzna mesylanu imatinibu
|
WO2011114337A1
(en)
|
2010-03-15 |
2011-09-22 |
Natco Pharma Limited |
Process for the preparation of highly pure crystalline imatinib base
|
WO2011119995A2
(en)
|
2010-03-26 |
2011-09-29 |
Cerulean Pharma Inc. |
Formulations and methods of use
|
US8987272B2
(en)
|
2010-04-01 |
2015-03-24 |
Critical Outcome Technologies Inc. |
Compounds and method for treatment of HIV
|
US8609842B2
(en)
|
2010-04-23 |
2013-12-17 |
Fujian South Pharmaceutical Co., Ltd. |
Method for synthesizing Imatinib
|
EP2382976A1
(en)
|
2010-04-30 |
2011-11-02 |
Hiroshima University |
Use of pdgf-r inhibitors for the treatment of lymph node metastasis of gastric cancer
|
WO2011158255A1
(en)
*
|
2010-06-16 |
2011-12-22 |
Aptuit Laurus Private Limited |
Process for preparation of stable imatintb mesylate alpha form
|
GEP20146195B
(en)
*
|
2010-06-16 |
2014-11-10 |
Takeda Pharmaceuticals Co |
Crystal of amide compound
|
US20130085161A1
(en)
|
2010-06-17 |
2013-04-04 |
Novartis Ag |
Piperidinyl substituted 1,3-dihydro-benzoimidazol-2-ylideneamine derivatives
|
WO2011157787A1
(en)
|
2010-06-17 |
2011-12-22 |
Novartis Ag |
Biphenyl substituted 1,3-dihydro-benzoimidazol-2-ylideneamine derivatives
|
EA024088B1
(ru)
|
2010-06-18 |
2016-08-31 |
КРКА, д.д., НОВО МЕСТО |
α-ФОРМА МЕЗИЛАТА ИМАТИНИБА, СПОСОБЫ ЕЕ ПОЛУЧЕНИЯ И СОДЕРЖАЩАЯ ЕЁ ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ
|
UA112517C2
(uk)
|
2010-07-06 |
2016-09-26 |
Новартіс Аг |
Тетрагідропіридопіримідинові похідні
|
MX2013001653A
(es)
|
2010-08-11 |
2013-05-22 |
Synthon Bv |
Granulado farmaceutico que comprende mesilato de imatinib
|
TR201007005A2
(tr)
|
2010-08-23 |
2011-09-21 |
Mustafa Nevzat İlaç Sanayi̇i̇ A.Ş. |
İmatinib baz üretim yöntemi
|
WO2012027716A1
(en)
|
2010-08-27 |
2012-03-01 |
Collabrx, Inc. |
Method to treat melanoma in braf inhibitor-resistant subjects
|
RU2456280C2
(ru)
*
|
2010-08-27 |
2012-07-20 |
Общество с ограниченной ответственностью "Химфармресурс" |
Кристаллическая n-модификация 4-[(4-метил-1-пиперазинил)метил]-n-[4-метил-3-[[4-(3-пиридинил)-2-пиримидинил]-амино]-фенил] бензамида метансульфоната, способ ее получения и фармацевтическая композиция на ее основе
|
WO2012035078A1
(en)
|
2010-09-16 |
2012-03-22 |
Novartis Ag |
17α-HYDROXYLASE/C17,20-LYASE INHIBITORS
|
US9034883B2
(en)
|
2010-11-15 |
2015-05-19 |
Boehringer Ingelheim International Gmbh |
Vasoprotective and cardioprotective antidiabetic therapy
|
CN102477031B
(zh)
*
|
2010-11-30 |
2015-07-15 |
浙江九洲药业股份有限公司 |
一种甲磺酸伊马替尼α晶型的制备方法
|
TR201010618A2
(tr)
*
|
2010-12-20 |
2012-07-23 |
Bi̇lgi̇ç Mahmut |
İmatinib içeren bir oral dozaj formu ve bu oral dozaj formunun üretimi
|
JP2014500308A
(ja)
|
2010-12-21 |
2014-01-09 |
ノバルティス アーゲー |
Vps34阻害剤としてのビヘテロアリール化合物
|
WO2012090221A1
(en)
|
2010-12-29 |
2012-07-05 |
Cadila Healthcare Limited |
Novel salts of imatinib
|
WO2012107500A1
(en)
|
2011-02-10 |
2012-08-16 |
Novartis Ag |
[1, 2, 4] triazolo [4, 3 -b] pyridazine compounds as inhibitors of the c-met tyrosine kinase
|
CN102146073A
(zh)
*
|
2011-02-23 |
2011-08-10 |
江苏先声药物研究有限公司 |
一种伊玛替尼甲烷磺酸盐α晶型新的制备方法
|
CN102649785B
(zh)
*
|
2011-02-23 |
2015-08-19 |
江苏先声药物研究有限公司 |
一种伊玛替尼甲烷磺酸盐β晶型的制备方法
|
WO2012116237A2
(en)
|
2011-02-23 |
2012-08-30 |
Intellikine, Llc |
Heterocyclic compounds and uses thereof
|
KR20200003933A
(ko)
|
2011-03-04 |
2020-01-10 |
뉴젠 세러퓨틱스 인코포레이티드 |
알킨 치환된 퀴나졸린 화합물 및 그것의 사용 방법
|
EP2683722A1
(en)
|
2011-03-08 |
2014-01-15 |
Novartis AG |
Fluorophenyl bicyclic heteroaryl compounds
|
PL394169A1
(pl)
|
2011-03-09 |
2012-09-10 |
Adamed Spółka Z Ograniczoną Odpowiedzialnością |
Kompozycja farmaceutyczna metanosulfonianu imatinibu do napełniania jednostkowych postaci dawkowania oraz sposób jej wytwarzania
|
JP2014509642A
(ja)
|
2011-03-31 |
2014-04-21 |
アイエヌディー−スイフト ラボラトリーズ リミテッド |
イマチニブ及びそのメシル酸塩の生成のための改良方法
|
ES2656218T3
(es)
|
2011-04-28 |
2018-02-26 |
Novartis Ag |
Inhibidores de 17 alfa-hidroxilasa/C17,20-liasa
|
CN103501612B
(zh)
|
2011-05-04 |
2017-03-29 |
阿里亚德医药股份有限公司 |
抑制表皮生长因子受体导致的癌症中细胞增殖的化合物
|
CN102918029B
(zh)
|
2011-05-17 |
2015-06-17 |
江苏康缘药业股份有限公司 |
4-苯胺-6-丁烯酰胺-7-烷醚喹唑啉衍生物及其制备方法和用途
|
ES2705950T3
(es)
|
2011-06-03 |
2019-03-27 |
Eisai R&D Man Co Ltd |
Biomarcadores para predecir y valorar la capacidad de respuesta de sujetos con cáncer de tiroides y de riñón a compuestos de lenvatinib
|
CA2838029A1
(en)
|
2011-06-09 |
2012-12-13 |
Novartis Ag |
Heterocyclic sulfonamide derivatives
|
WO2012175520A1
(en)
|
2011-06-20 |
2012-12-27 |
Novartis Ag |
Hydroxy substituted isoquinolinone derivatives
|
US8859586B2
(en)
|
2011-06-20 |
2014-10-14 |
Novartis Ag |
Cyclohexyl isoquinolinone compounds
|
US9750700B2
(en)
|
2011-06-22 |
2017-09-05 |
Natco Pharma Limited |
Imatinib mesylate oral pharmaceutical composition and process for preparation thereof
|
EP2723740A1
(en)
|
2011-06-27 |
2014-04-30 |
Novartis AG |
Solid forms and salts of tetrahydro-pyrido-pyrimidine derivatives
|
ITMI20111309A1
(it)
|
2011-07-14 |
2013-01-15 |
Italiana Sint Spa |
Procedimento di preparazione di imatinib mesilato
|
CN102321070B
(zh)
*
|
2011-07-27 |
2013-05-22 |
江苏先声药物研究有限公司 |
反溶剂重结晶法制备伊玛替尼甲烷磺酸盐α晶型
|
EP2755976B1
(en)
|
2011-09-15 |
2018-07-18 |
Novartis AG |
6-substituted 3-(quinolin-6-ylthio)-[1,2,4]triazolo[4,3-a]pyridines as c-met tyrosine kinase inhibitors
|
WO2013063003A1
(en)
|
2011-10-28 |
2013-05-02 |
Novartis Ag |
Method of treating gastrointestinal stromal tumors
|
SG11201400543TA
(en)
|
2011-10-28 |
2014-08-28 |
Novartis Ag |
Method of treating gastrointestinal stromal tumors
|
US9707231B2
(en)
|
2011-11-01 |
2017-07-18 |
Modgene, Llc |
Compositions and methods for reduction of amyloid-beta load
|
JP5992054B2
(ja)
|
2011-11-29 |
2016-09-14 |
ノバルティス アーゲー |
ピラゾロピロリジン化合物
|
US9408885B2
(en)
|
2011-12-01 |
2016-08-09 |
Vib Vzw |
Combinations of therapeutic agents for treating melanoma
|
EP2604596A1
(en)
|
2011-12-16 |
2013-06-19 |
Deva Holding Anonim Sirketi |
Polymorphs of imatinib
|
EP2794594A1
(en)
|
2011-12-22 |
2014-10-29 |
Novartis AG |
Quinoline derivatives
|
AP4055A
(en)
|
2011-12-22 |
2017-03-07 |
Novartis Ag |
Dihydro-benzo-oxazine and dihydro-pyrido-oxazine derivatives
|
CA2859869A1
(en)
|
2011-12-23 |
2013-06-27 |
Novartis Ag |
Compounds for inhibiting the interaction of bcl2 with binding partners
|
US20130178520A1
(en)
|
2011-12-23 |
2013-07-11 |
Duke University |
Methods of treatment using arylcyclopropylamine compounds
|
US9126980B2
(en)
|
2011-12-23 |
2015-09-08 |
Novartis Ag |
Compounds for inhibiting the interaction of BCL2 with binding partners
|
CA2859873A1
(en)
|
2011-12-23 |
2013-06-27 |
Novartis Ag |
Compounds for inhibiting the interaction of bcl2 with binding partners
|
BR112014015308A2
(pt)
|
2011-12-23 |
2017-06-13 |
Novartis Ag |
compostos para inibição da interação de bcl2 com contrapartes de ligação
|
CA2859876A1
(en)
|
2011-12-23 |
2013-06-27 |
Novartis Ag |
Compounds for inhibiting the interaction of bcl2 with binding partners
|
PL226174B1
(pl)
|
2011-12-30 |
2017-06-30 |
Inst Farm |
Polaczenie analogu witaminy D z imatinibem do stosowania w leczeniu skojarzonym niedrobnokomorkowego raka pluc
|
JO3357B1
(ar)
|
2012-01-26 |
2019-03-13 |
Novartis Ag |
مركبات إيميدازوبيروليدينون
|
EP2817030A1
(en)
|
2012-02-21 |
2014-12-31 |
Ranbaxy Laboratories Limited |
Stable dosage forms of imatinib mesylate
|
CN102617549A
(zh)
*
|
2012-03-02 |
2012-08-01 |
瑞阳制药有限公司 |
甲磺酸伊马替尼β晶型的制备方法
|
WO2013136141A1
(en)
|
2012-03-13 |
2013-09-19 |
Fresenius Kabi Oncology Ltd. |
An improved process for the preparation of alpha form of imatinib mesylate
|
GB201204810D0
(en)
|
2012-03-20 |
2012-05-02 |
Pharos Pharmaceutical Oriented Services Ltd |
Pharmaceutical compositions
|
CA2868202C
(en)
|
2012-04-03 |
2021-08-10 |
Novartis Ag |
Combination products with tyrosine kinase inhibitors and their use
|
CN102617552A
(zh)
*
|
2012-04-06 |
2012-08-01 |
江南大学 |
一种制备α晶型甲磺酸伊马替尼的结晶方法
|
CN102633775B
(zh)
*
|
2012-04-06 |
2013-07-17 |
江南大学 |
一种甲磺酸伊马替尼α晶型的制备方法
|
JP2013216644A
(ja)
*
|
2012-04-11 |
2013-10-24 |
Takada Seiyaku Kk |
イマチニブメシル酸塩経口投与製剤
|
WO2013169401A1
(en)
|
2012-05-05 |
2013-11-14 |
Ariad Pharmaceuticals, Inc. |
Compounds for inhibiting cell proliferation in egfr-driven cancers
|
US9365576B2
(en)
|
2012-05-24 |
2016-06-14 |
Novartis Ag |
Pyrrolopyrrolidinone compounds
|
JP6427097B2
(ja)
|
2012-06-15 |
2018-11-21 |
ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドThe Brigham and Women’s Hospital, Inc. |
癌を処置するための組成物および該組成物を製造するための方法
|
EP2864313A1
(en)
|
2012-06-22 |
2015-04-29 |
Basf Se |
Multicomponent crystals comprising imatinib mesilate and selected co-crystal formers
|
KR101242955B1
(ko)
*
|
2012-06-25 |
2013-03-12 |
제일약품주식회사 |
이마티닙 메실레이트 결정형 α의 제조 방법
|
JP2015522070A
(ja)
|
2012-07-11 |
2015-08-03 |
ノバルティス アーゲー |
消化管間質腫瘍を治療する方法
|
WO2014016848A2
(en)
|
2012-07-24 |
2014-01-30 |
Laurus Labs Private Limited |
Solid forms of tyrosine kinase inhibitors, process for the preparation and their pharmaceutical composition thereof
|
CA2880236C
(en)
|
2012-07-27 |
2022-09-13 |
Antonius Martinus Gustave Bunt |
Efflux inhibitor compositions and methods of treatment using the same
|
CN103570677B
(zh)
*
|
2012-08-02 |
2017-03-01 |
广东东阳光药业有限公司 |
一种α晶型甲磺酸伊马替尼的制备方法
|
EP2879675B1
(en)
|
2012-08-06 |
2019-11-13 |
Duke University |
Compounds and methods for targeting hsp90
|
WO2014041551A1
(en)
|
2012-09-14 |
2014-03-20 |
Natco Pharma Limited |
Formulation comprising imatinib as oral solution
|
JP2015531355A
(ja)
|
2012-09-28 |
2015-11-02 |
ハンジョウ ベンシェン ファーマシューティカル シーオー., エルティーディー.Hangzhou Bensheng Pharmaceutical Co., Ltd. |
腫瘍治療のための薬剤組成物及びその適用
|
US9439903B2
(en)
|
2012-10-25 |
2016-09-13 |
Cadila Healthcare Limited |
Process for the preparation of amorphous imatinib mesylate
|
CN105377288B
(zh)
|
2012-11-05 |
2019-11-15 |
达纳-法伯癌症研究所股份有限公司 |
Xbp1、cd138和cs1肽的组合物制备药物的用途
|
TW201422625A
(zh)
|
2012-11-26 |
2014-06-16 |
Novartis Ag |
二氫-吡啶并-□衍生物之固體形式
|
EP2749269A1
(en)
|
2012-12-31 |
2014-07-02 |
Deva Holding Anonim Sirketi |
Process for the preparation of adsorbates of imatinib
|
EP2749271A1
(en)
|
2012-12-31 |
2014-07-02 |
Deva Holding Anonim Sirketi |
Optimized manufacturing method and pharmaceutical formulation of imatinib
|
EP2749557A1
(en)
|
2012-12-31 |
2014-07-02 |
Deva Holding Anonim Sirketi |
Process for preparation of alpha polymorph of imatinib mesylate from IPA and THF solvate forms of imatinib mesylate
|
WO2014115077A1
(en)
|
2013-01-22 |
2014-07-31 |
Novartis Ag |
Substituted purinone compounds
|
EP2948453B1
(en)
|
2013-01-22 |
2017-08-02 |
Novartis AG |
Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the p53/mdm2 interaction
|
PT2958943T
(pt)
|
2013-02-20 |
2019-12-17 |
Novartis Ag |
Tratamento do cancro usando recetor de antigénios quiméricos anti-egfrviii humanizados
|
WO2014128612A1
(en)
|
2013-02-20 |
2014-08-28 |
Novartis Ag |
Quinazolin-4-one derivatives
|
CA2906542A1
(en)
|
2013-03-15 |
2014-09-25 |
Intellikine, Llc |
Combination of kinase inhibitors and uses thereof
|
GB201304699D0
(en)
|
2013-03-15 |
2013-05-01 |
Remedica Ltd |
Pharmaceutical compositions
|
WO2014155268A2
(en)
|
2013-03-25 |
2014-10-02 |
Novartis Ag |
Fgf-r tyrosine kinase activity inhibitors - use in diseases associated with lack of or reduced snf5 activity
|
US9611283B1
(en)
|
2013-04-10 |
2017-04-04 |
Ariad Pharmaceuticals, Inc. |
Methods for inhibiting cell proliferation in ALK-driven cancers
|
EP2803353B1
(en)
|
2013-05-14 |
2018-05-23 |
Hetero Research Foundation |
Compositions of Imatinib
|
US20150018376A1
(en)
|
2013-05-17 |
2015-01-15 |
Novartis Ag |
Pyrimidin-4-yl)oxy)-1h-indole-1-carboxamide derivatives and use thereof
|
UY35675A
(es)
|
2013-07-24 |
2015-02-27 |
Novartis Ag |
Derivados sustituidos de quinazolin-4-ona
|
CA2919498C
(en)
|
2013-07-31 |
2023-07-25 |
Windward Pharma, Inc. |
Aerosol nintedanib compounds and uses thereof
|
WO2015022663A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
WO2015022664A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
US9227969B2
(en)
|
2013-08-14 |
2016-01-05 |
Novartis Ag |
Compounds and compositions as inhibitors of MEK
|
WO2015042078A2
(en)
|
2013-09-22 |
2015-03-26 |
Calitor Sciences, Llc |
Substituted aminopyrimidine compounds and methods of use
|
US9901579B2
(en)
|
2013-10-17 |
2018-02-27 |
Sartar Therapeutics Ltd |
Compositions comprising phosphodiesterase inhibitors for use in the treatment of a solid tumor in a human patient
|
US9636340B2
(en)
|
2013-11-12 |
2017-05-02 |
Ayyappan K. Rajasekaran |
Kinase inhibitors
|
TW201605450A
(zh)
|
2013-12-03 |
2016-02-16 |
諾華公司 |
Mdm2抑制劑與BRAF抑制劑之組合及其用途
|
WO2015110949A1
(en)
|
2014-01-22 |
2015-07-30 |
Novartis Ag |
Imatinib as cholesterol decreasing agent
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
CN103800671B
(zh)
*
|
2014-02-11 |
2016-02-10 |
王思成 |
一种治疗阿弗他溃疡的中药制剂
|
CN106103484B
(zh)
|
2014-03-14 |
2021-08-20 |
诺华股份有限公司 |
针对lag-3的抗体分子及其用途
|
WO2015148714A1
(en)
|
2014-03-25 |
2015-10-01 |
Duke University |
Heat shock protein 70 (hsp-70) receptor ligands
|
WO2015145388A2
(en)
|
2014-03-27 |
2015-10-01 |
Novartis Ag |
Methods of treating colorectal cancers harboring upstream wnt pathway mutations
|
US9399637B2
(en)
|
2014-03-28 |
2016-07-26 |
Calitor Sciences, Llc |
Substituted heteroaryl compounds and methods of use
|
AU2015241198A1
(en)
|
2014-04-03 |
2016-11-17 |
Invictus Oncology Pvt. Ltd. |
Supramolecular combinatorial therapeutics
|
EP2927223B1
(en)
|
2014-04-04 |
2016-06-29 |
F.I.S.- Fabbrica Italiana Sintetici S.p.A. |
Process for preparing imatinib and salts thereof, free of genotoxic impurity f
|
CN104974133B
(zh)
*
|
2014-04-09 |
2018-04-27 |
石药集团中奇制药技术(石家庄)有限公司 |
一种甲磺酸伊马替尼晶型及其制备方法
|
CN104055745A
(zh)
*
|
2014-06-11 |
2014-09-24 |
连云港杰瑞药业有限公司 |
一种甲磺酸伊马替尼片的制备方法
|
WO2016011658A1
(en)
|
2014-07-25 |
2016-01-28 |
Novartis Ag |
Combination therapy
|
CA2954862A1
(en)
|
2014-07-31 |
2016-02-04 |
Novartis Ag |
Combination therapy
|
JO3783B1
(ar)
|
2014-08-28 |
2021-01-31 |
Eisai R&D Man Co Ltd |
مشتق كوينولين عالي النقاء وطريقة لإنتاجه
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
CU20170052A7
(es)
|
2014-10-14 |
2017-11-07 |
Dana Farber Cancer Inst Inc |
Moléculas de anticuerpo que se unen a pd-l1
|
TN2017000157A1
(en)
|
2014-10-21 |
2018-10-19 |
Ariad Pharma Inc |
Crystalline forms of 5-chloro-n4-[-2-(dimethylphosphoryl) phenyl]-n2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl) piperidin-1-yl] pyrimidine-2,4-diamine
|
EP3233918A1
(en)
|
2014-12-19 |
2017-10-25 |
Novartis AG |
Combination therapies
|
DK3263106T3
(da)
|
2015-02-25 |
2024-01-08 |
Eisai R&D Man Co Ltd |
Fremgangsmåde til undertrykkelse af bitterhed af quinolinderivat
|
CA2978226A1
(en)
|
2015-03-04 |
2016-09-09 |
Merck Sharpe & Dohme Corp. |
Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer
|
MY190404A
(en)
|
2015-03-10 |
2022-04-21 |
Aduro Biotech Inc |
Compositions and methods for activating "stimulator of interferon gene"-dependent signalling
|
CN106518844A
(zh)
*
|
2015-04-14 |
2017-03-22 |
江苏豪森药业集团有限公司 |
适合药用的甲磺酸伊马替尼晶型及其制备方法
|
CN107801379B
(zh)
|
2015-06-16 |
2021-05-25 |
卫材R&D管理有限公司 |
抗癌剂
|
EP3316902A1
(en)
|
2015-07-29 |
2018-05-09 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
SI3317301T1
(sl)
|
2015-07-29 |
2021-10-29 |
Novartis Ag |
Kombinirane terapije, ki obsegajo molekule protitelesa na LAG-3
|
WO2017044434A1
(en)
|
2015-09-11 |
2017-03-16 |
Sunshine Lake Pharma Co., Ltd. |
Substituted heteroaryl compounds and methods of use
|
BR112018008904A2
(pt)
|
2015-11-03 |
2018-11-27 |
Janssen Biotech Inc |
anticorpos que se ligam especificamente a tim-3 e seus usos
|
WO2017078647A1
(en)
|
2015-11-05 |
2017-05-11 |
Koçak Farma Ilaç Ve Kimya Sanayi Anonim Şirketi |
Pharmaceutical compositions of imatinib
|
CN105503825B
(zh)
*
|
2015-12-16 |
2019-01-11 |
齐鲁天和惠世制药有限公司 |
一种甲磺酸伊马替尼β晶型的制备方法
|
CA3007671A1
(en)
|
2015-12-17 |
2017-06-22 |
Novartis Ag |
Antibody molecules to pd-1 and uses thereof
|
SG11201805331QA
(en)
|
2015-12-24 |
2018-07-30 |
Takeda Pharmaceuticals Co |
Cocrystal, production method thereof, and medicament containing cocrystal
|
EA035891B1
(ru)
|
2016-01-25 |
2020-08-27 |
КРКА, д.д., НОВО МЕСТО |
Быстродиспергируемая фармацевтическая композиция, включающая ингибитор тирозинкиназы
|
EA038531B1
(ru)
|
2016-03-25 |
2021-09-10 |
Аб Сьянс |
Способ лечения амиотрофного латерального склероза, применение фармацевтической композиции, содержащей мазитиниб
|
WO2017184956A1
(en)
|
2016-04-22 |
2017-10-26 |
Duke University |
Compounds and methods for targeting hsp90
|
EP3257499A1
(en)
|
2016-06-17 |
2017-12-20 |
Vipharm S.A. |
Process for preparation of imatinib methanesulfonate capsules
|
EP3507367A4
(en)
|
2016-07-05 |
2020-03-25 |
Aduro BioTech, Inc. |
CYCLIC DINUCLEOTID COMPOUNDS WITH INCLUDED NUCLEIC ACIDS AND USES THEREOF
|
US20190209669A1
(en)
|
2016-08-23 |
2019-07-11 |
Oncopep, Inc. |
Peptide vaccines and durvalumab for treating breast cancer
|
WO2018039203A1
(en)
|
2016-08-23 |
2018-03-01 |
Oncopep, Inc. |
Peptide vaccines and durvalumab for treating multiple myeloma
|
JP2019536471A
(ja)
|
2016-09-27 |
2019-12-19 |
セロ・セラピューティクス・インコーポレイテッドCERO Therapeutics, Inc. |
キメラエンガルフメント受容体分子
|
US10927083B2
(en)
|
2016-09-29 |
2021-02-23 |
Duke University |
Substituted benzimidazoles as inhibitors of transforming growth factor-β kinase
|
US10207998B2
(en)
|
2016-09-29 |
2019-02-19 |
Duke University |
Substituted benzimidazole and substituted benzothiazole inhibitors of transforming growth factor-β kinase and methods of use thereof
|
EP3527211B1
(en)
|
2016-10-17 |
2023-08-23 |
Delta-Fly Pharma, Inc. |
Pharmaceutical composition for treatment or remission of chronic myelogenous leukemia
|
WO2018089404A1
(en)
|
2016-11-11 |
2018-05-17 |
Mallinckrodt Nuclear Medicine Llc |
Processes for generating germanium-68 with reduced volatiles
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
WO2018237173A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
ANTIBODY MOLECULES DIRECTED AGAINST CD73 AND CORRESPONDING USES
|
CA3073421A1
(en)
|
2017-09-26 |
2019-04-04 |
Daniel Mark COREY |
Chimeric engulfment receptor molecules and methods of use
|
US20200276304A1
(en)
|
2017-10-24 |
2020-09-03 |
Oncopep, Inc. |
Peptide vaccines and pembrolizumab for treating breast cancer
|
WO2019083960A1
(en)
|
2017-10-24 |
2019-05-02 |
Oncopep, Inc. |
PEPTIDE VACCINES AND HDAC INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA
|
EP3710006A4
(en)
|
2017-11-19 |
2021-09-01 |
Sunshine Lake Pharma Co., Ltd. |
SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR METHODS OF USE
|
JP7021356B2
(ja)
|
2017-12-21 |
2022-02-16 |
ヘフェイ インスティテューツ オブ フィジカル サイエンス, チャイニーズ アカデミー オブ サイエンシーズ |
ピリミジン誘導体系キナーゼ阻害剤類
|
KR20200112900A
(ko)
|
2018-01-20 |
2020-10-05 |
선샤인 레이크 파르마 컴퍼니 리미티드 |
치환된 아미노피리미딘 화합물 및 이의 사용 방법
|
US20210024607A1
(en)
|
2018-03-28 |
2021-01-28 |
Cero Therapeutics, Inc. |
Expression vectors for chimeric engulfment receptors, genetically modified host cells, and uses thereof
|
RU2020135107A
(ru)
|
2018-03-28 |
2022-04-29 |
Серо Терапьютикс, Инк. |
Клеточные иммунотерапевтические композиции и их применения
|
US20210087251A1
(en)
|
2018-03-28 |
2021-03-25 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
TW202015726A
(zh)
|
2018-05-30 |
2020-05-01 |
瑞士商諾華公司 |
Entpd2抗體、組合療法、及使用該等抗體和組合療法之方法
|
WO2020023628A1
(en)
|
2018-07-24 |
2020-01-30 |
Hygia Pharmaceuticals, Llc |
Compounds, derivatives, and analogs for cancer
|
BR112021011894A2
(pt)
|
2018-12-21 |
2021-09-08 |
Daiichi Sankyo Company, Limited |
Composição farmacêutica
|
JP2022548881A
(ja)
|
2019-09-18 |
2022-11-22 |
ノバルティス アーゲー |
Entpd2抗体、組合せ療法並びに抗体及び組合せ療法を使用する方法
|
EP4038097A1
(en)
|
2019-10-03 |
2022-08-10 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
US20220395553A1
(en)
|
2019-11-14 |
2022-12-15 |
Cohbar, Inc. |
Cxcr4 antagonist peptides
|
WO2021185844A1
(en)
|
2020-03-16 |
2021-09-23 |
Pvac Medical Technologies Ltd |
Use of substance and pharmaceutical composition thereof, and medical treatments or uses thereof
|
WO2021233534A1
(en)
|
2020-05-20 |
2021-11-25 |
Pvac Medical Technologies Ltd |
Use of substance and pharmaceutical composition thereof, and medical treatments or uses thereof
|
EP4192509A1
(en)
|
2020-08-05 |
2023-06-14 |
Ellipses Pharma Ltd |
Treatment of cancer using a cyclodextrin-containing polymer-topoisomerase inhibitor conjugate and a parp inhibitor
|
WO2022036287A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Anti-cd72 chimeric receptors and uses thereof
|
WO2022036285A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Compositions and methods for treating cancer with chimeric tim receptors in combination with inhibitors of poly (adp-ribose) polymerase
|
WO2022036265A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Chimeric tim receptors and uses thereof
|
TW202237638A
(zh)
|
2020-12-09 |
2022-10-01 |
日商武田藥品工業股份有限公司 |
烏苷酸環化酶c(gcc)抗原結合劑之組成物及其使用方法
|
CN117203223A
(zh)
|
2021-02-26 |
2023-12-08 |
凯洛尼亚疗法有限公司 |
淋巴细胞靶向慢病毒载体
|
WO2023010097A1
(en)
|
2021-07-28 |
2023-02-02 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
CN114957206B
(zh)
*
|
2022-04-11 |
2024-02-27 |
中国药科大学 |
伊马替尼共晶及其制备方法
|
WO2024030441A1
(en)
|
2022-08-02 |
2024-02-08 |
National University Corporation Hokkaido University |
Methods of improving cellular therapy with organelle complexes
|