NO970293D0 - Substituerte camptotecinderivater og fremgangsmåte for dens fremstilling - Google Patents

Substituerte camptotecinderivater og fremgangsmåte for dens fremstilling

Info

Publication number
NO970293D0
NO970293D0 NO970293A NO970293A NO970293D0 NO 970293 D0 NO970293 D0 NO 970293D0 NO 970293 A NO970293 A NO 970293A NO 970293 A NO970293 A NO 970293A NO 970293 D0 NO970293 D0 NO 970293D0
Authority
NO
Norway
Prior art keywords
preparation
camptothecin derivatives
substituted camptothecin
substituted
derivatives
Prior art date
Application number
NO970293A
Other languages
English (en)
Other versions
NO970293L (no
Inventor
Walter Cabri
Ilaria Candiani
Angelo Bedeschi
Franco Zarini
Sergio Penco
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of NO970293D0 publication Critical patent/NO970293D0/no
Publication of NO970293L publication Critical patent/NO970293L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO970293A 1995-05-26 1997-01-23 Substituerte camptothecinderivater og fremgangsmåte for deres fremstilling NO970293L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9510716.5A GB9510716D0 (en) 1995-05-26 1995-05-26 Substituted camptothecin derivatives and process for their preparation
PCT/EP1996/002008 WO1996037496A1 (en) 1995-05-26 1996-05-10 Substituted camptothecin derivatives and process for their preparation

Publications (2)

Publication Number Publication Date
NO970293D0 true NO970293D0 (no) 1997-01-23
NO970293L NO970293L (no) 1997-03-06

Family

ID=10775098

Family Applications (1)

Application Number Title Priority Date Filing Date
NO970293A NO970293L (no) 1995-05-26 1997-01-23 Substituerte camptothecinderivater og fremgangsmåte for deres fremstilling

Country Status (18)

Country Link
US (1) US5856333A (no)
EP (1) EP0777670B1 (no)
JP (1) JPH10503220A (no)
CN (1) CN1159192A (no)
AR (1) AR003126A1 (no)
AT (1) ATE262532T1 (no)
AU (1) AU5817996A (no)
BR (1) BR9606396A (no)
CA (1) CA2194700A1 (no)
DE (1) DE69631943D1 (no)
GB (1) GB9510716D0 (no)
HU (1) HUP9702400A3 (no)
IL (1) IL118410A0 (no)
NO (1) NO970293L (no)
NZ (1) NZ308514A (no)
PL (1) PL318279A1 (no)
WO (1) WO1996037496A1 (no)
ZA (1) ZA964138B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096336A (en) * 1996-01-30 2000-08-01 The Stehlin Foundation For Cancer Research Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
GB9702807D0 (en) 1997-02-12 1997-04-02 Pharmacia & Upjohn Spa Alkynyl-substituted camptothecins and process for their preparation
AU6272598A (en) * 1997-02-14 1998-09-08 Bionumerik Pharmaceuticals, Inc. Highly lipophilic camptothecin derivatives
CA2289625A1 (en) 1997-05-15 1998-11-19 Charles Van Jackson Antithrombotic compound
HUP9701554D0 (en) * 1997-09-18 1997-11-28 Human Oltoanyagtermeloe Gyogys Pharmaceutical composition containing plazma proteins
US6228855B1 (en) 1999-08-03 2001-05-08 The Stehlin Foundation For Cancer Research Aromatic esters of camptothecins and methods to treat cancers
US6352996B1 (en) 1999-08-03 2002-03-05 The Stehlin Foundation For Cancer Research Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US6288072B1 (en) 1999-12-29 2001-09-11 Monroe E. Wall Camptothecin β-alanine esters with topoisomerase I inhibition
EE200200471A (et) 2000-02-28 2003-12-15 Aventis Pharma S.A. Farmatseutiline kompositsioon, mis sisaldab kamptotetsiini või selle derivaati kombinatsioonis pürimidiini derivaadiga ning on ette nähtud vähktõve raviks
US6545010B2 (en) 2000-03-17 2003-04-08 Aventis Pharma S.A. Composition comprising camptothecin or a camptothecin derivative and a platin derivative for the treatment of cancer
US6548488B2 (en) 2000-03-17 2003-04-15 Aventis Pharma S.A. Composition comprising camptothecin or a camptothecin derivative and an alkylating agent for the treatment of cancer
US6486320B2 (en) 2000-09-15 2002-11-26 Aventis Pharma S.A. Preparation of camptothecin and of its derivatives
CN1200712C (zh) 2000-10-27 2005-05-11 阿文蒂斯药物股份有限公司 用于治疗癌症的含喜树碱和1,2－二苯乙烯衍生物的组合物
RU2004132721A (ru) 2002-04-08 2005-06-27 Глэксо Груп Лимитед (GB) (2-алкокси)фенил)циклопент-1-енил)ароматическая карбо- и гетероциклическая карбоновая кислота и ее производные
GB0225548D0 (en) 2002-11-01 2002-12-11 Glaxo Group Ltd Compounds
CN100406460C (zh) * 2003-11-10 2008-07-30 中国科学院上海药物研究所 喜树碱的新衍生物、制备方法和用途
US20090104254A1 (en) 2004-12-22 2009-04-23 Rutgers, The State University Of New Jersey Controlled Release Hydrogels
CA2658015A1 (en) 2006-03-30 2007-10-11 Diatos S.A. Camptothecin-peptide conjugates and pharmaceutical compositions containing the same
CN101880285B (zh) * 2010-06-24 2012-07-04 华东师范大学 一种烯丙基取代喜树碱化合物的合成方法
US20140086975A1 (en) 2010-10-15 2014-03-27 Rutgers, The State University Of New Jersey Hydrogel formulation for dermal and ocular delivery
CN104774209B (zh) * 2014-01-15 2018-06-19 上海海和药物研究开发有限公司 一种9-烯丙基喜树碱衍生物的合成方法
TW202304929A (zh) 2021-04-29 2023-02-01 美商艾伯維有限公司 抗c-Met抗體藥物結合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364858A (en) * 1987-03-31 1994-11-15 Research Triangle Institute Camptothecin analogs as potent inhibitors of topoisomerase I
US5340817A (en) * 1987-04-14 1994-08-23 Research Triangle Institute Method of treating tumors with anti-tumor effective camptothecin compounds
US5122606A (en) * 1987-04-14 1992-06-16 Research Triangle Institute 10,11-methylenedioxy camptothecins
US5004758A (en) * 1987-12-01 1991-04-02 Smithkline Beecham Corporation Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells
JPH0615547B2 (ja) * 1988-01-20 1994-03-02 株式会社ヤクルト本社 新規なカンプトテシン誘導体
WO1991004260A2 (en) * 1989-09-15 1991-04-04 Research Triangle Institute 10,11-methylenedioxy-20(rs)-camptothecin and 10,11-methylenedioxy-20(s)-camptothecin analogs
GB9319944D0 (en) * 1993-09-28 1993-11-17 Erba Carlo Spa Process for the preparation of 9-amino camptothecin
GB9402934D0 (en) * 1994-02-16 1994-04-06 Erba Carlo Spa Camptothecin derivatives and process for their preparation

Also Published As

Publication number Publication date
ATE262532T1 (de) 2004-04-15
DE69631943D1 (de) 2004-04-29
IL118410A0 (en) 1996-09-12
AU5817996A (en) 1996-12-11
GB9510716D0 (en) 1995-07-19
AR003126A1 (es) 1998-07-08
EP0777670A1 (en) 1997-06-11
JPH10503220A (ja) 1998-03-24
HUP9702400A3 (en) 1998-07-28
HUP9702400A2 (hu) 1998-06-29
CA2194700A1 (en) 1996-11-28
PL318279A1 (en) 1997-06-09
WO1996037496A1 (en) 1996-11-28
ZA964138B (en) 1996-11-27
NZ308514A (en) 1998-06-26
NO970293L (no) 1997-03-06
CN1159192A (zh) 1997-09-10
US5856333A (en) 1999-01-05
BR9606396A (pt) 1997-10-14
EP0777670B1 (en) 2004-03-24

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