LU92508I2 - Cabozantinib et toutes les formes thérapeutiquement équivalentes qui en dérivent telles que protégées par le brevet de base, y compris les sels pharmacetuiquement acceptables - Google Patents

Cabozantinib et toutes les formes thérapeutiquement équivalentes qui en dérivent telles que protégées par le brevet de base, y compris les sels pharmacetuiquement acceptables Download PDF

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Publication number
LU92508I2
LU92508I2 LU92508C LU92508C LU92508I2 LU 92508 I2 LU92508 I2 LU 92508I2 LU 92508 C LU92508 C LU 92508C LU 92508 C LU92508 C LU 92508C LU 92508 I2 LU92508 I2 LU 92508I2
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Luxembourg
Prior art keywords
compounds
pharmacetually
cabozantinib
protected
acceptable salts
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LU92508C
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English (en)
French (fr)
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Exelixis Inc
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Application filed by Exelixis Inc filed Critical Exelixis Inc
Publication of LU92508I2 publication Critical patent/LU92508I2/xx

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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
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    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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JP2014055190A (ja) 2014-03-27
SI2392564T1 (sl) 2014-02-28
WO2005030140A2 (en) 2005-04-07
AU2004275842A1 (en) 2005-04-07
HRP20110707T1 (hr) 2011-10-31
CA2537812C (en) 2013-01-22
JP2019070015A (ja) 2019-05-09
US20120022065A1 (en) 2012-01-26
US8178532B2 (en) 2012-05-15
BE2014C055I2 (ja) 2023-12-14
HUS1400052I1 (hu) 2022-02-28
EP2609919A2 (en) 2013-07-03
ES2466818T3 (es) 2014-06-11
JP2015131859A (ja) 2015-07-23
US20110077233A1 (en) 2011-03-31
EP2409704A2 (en) 2012-01-25
EP2609919A3 (en) 2014-02-26
ES2651730T3 (es) 2018-01-29
US20210253530A9 (en) 2021-08-19
JP2014055191A (ja) 2014-03-27
ES2369652T3 (es) 2011-12-02
SI2392565T1 (sl) 2014-05-30
US20130252940A1 (en) 2013-09-26
EP1673085B1 (en) 2011-11-09
SI2210607T1 (sl) 2011-11-30
US8476298B2 (en) 2013-07-02
US20070054928A1 (en) 2007-03-08
US7579473B2 (en) 2009-08-25
EP3329918A2 (en) 2018-06-06
US20200331860A1 (en) 2020-10-22
JP2010235632A (ja) 2010-10-21
EP2213661B1 (en) 2011-07-20
EP2392564A1 (en) 2011-12-07
HRP20140563T1 (hr) 2014-07-18
JP2021050233A (ja) 2021-04-01
HK1256476A1 (zh) 2019-09-27
PL2392565T3 (pl) 2014-08-29
US20090105299A1 (en) 2009-04-23
JP2010280674A (ja) 2010-12-16
EP2392564B1 (en) 2013-10-23
JP2011042686A (ja) 2011-03-03
US8497284B2 (en) 2013-07-30
JP2010265302A (ja) 2010-11-25
JP2024023447A (ja) 2024-02-21
EP2409704A3 (en) 2013-02-13
WO2005030140A3 (en) 2005-05-19
JP5185331B2 (ja) 2013-04-17
US20140155396A1 (en) 2014-06-05
HRP20140012T1 (hr) 2014-02-14
EP2392565A1 (en) 2011-12-07
NL300678I2 (ja) 2017-01-31
CY1111956T1 (el) 2015-11-04
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US20120184523A1 (en) 2012-07-19
CY2014037I2 (el) 2019-07-10
HRP20110810T1 (hr) 2011-12-31
JP4638436B2 (ja) 2011-02-23
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US20090170896A1 (en) 2009-07-02
PL2213661T3 (pl) 2011-12-30
EP2409704B1 (en) 2017-09-20
ES2925655T3 (es) 2022-10-19
EP2392565B1 (en) 2014-03-19
HK1143068A1 (en) 2010-12-24
SI2213661T1 (sl) 2011-11-30
EP1673085A2 (en) 2006-06-28
ES2436888T3 (es) 2014-01-07
EP2210607A1 (en) 2010-07-28
ATE517091T1 (de) 2011-08-15
ATE532782T1 (de) 2011-11-15
DK2210607T3 (da) 2011-12-12
EP1673085A4 (en) 2008-12-10
US20140155378A9 (en) 2014-06-05
US20070244116A1 (en) 2007-10-18
US20160185725A1 (en) 2016-06-30
JP2007506777A (ja) 2007-03-22
US20170355678A1 (en) 2017-12-14
AU2004275842B2 (en) 2010-09-02
EP2210607B1 (en) 2011-08-17
JP2014074059A (ja) 2014-04-24
JP2010235631A (ja) 2010-10-21
AU2010204459A1 (en) 2010-08-19
JP5185332B2 (ja) 2013-04-17
AU2010204461A1 (en) 2010-08-19
CA2744997A1 (en) 2005-04-07
HK1164313A1 (en) 2012-09-21
ATE520403T1 (de) 2011-09-15
CA2537812A1 (en) 2005-04-07
EP2213661A1 (en) 2010-08-04
PT2210607E (pt) 2012-01-31
AU2010204459B2 (en) 2013-06-20
PT2213661E (pt) 2011-12-15
DK2213661T3 (da) 2011-09-19
US11124482B2 (en) 2021-09-21
EP3329918B1 (en) 2022-05-25
CY2014037I1 (el) 2015-11-04
US20150376133A1 (en) 2015-12-31
HK1141799A1 (en) 2010-11-19
AU2010204461B2 (en) 2013-06-20
JP5325173B2 (ja) 2013-10-23
PL2210607T3 (pl) 2012-01-31
US8067436B2 (en) 2011-11-29
EP2612853A1 (en) 2013-07-10
US20070225307A1 (en) 2007-09-27
JP2017160270A (ja) 2017-09-14
DK2392565T3 (da) 2014-05-05
EP3329918A3 (en) 2018-08-15
CY1112056T1 (el) 2015-11-04

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