BR112013004581A2 - imunoglobulinas de domínio variável dual e seus usos - Google Patents

imunoglobulinas de domínio variável dual e seus usos

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Publication number
BR112013004581A2
BR112013004581A2 BR112013004581A BR112013004581A BR112013004581A2 BR 112013004581 A2 BR112013004581 A2 BR 112013004581A2 BR 112013004581 A BR112013004581 A BR 112013004581A BR 112013004581 A BR112013004581 A BR 112013004581A BR 112013004581 A2 BR112013004581 A2 BR 112013004581A2
Authority
BR
Brazil
Prior art keywords
variable domain
dual variable
domain immunoglobulins
production
immunoglobulins
Prior art date
Application number
BR112013004581A
Other languages
English (en)
Inventor
G Salfeld Jochen
J Mcpherson Michael
Ghayur Tariq
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45724062&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112013004581(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of BR112013004581A2 publication Critical patent/BR112013004581A2/pt

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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
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    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
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    • GPHYSICS
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    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

imunoglobulinas de domínio variável dual e seus usos. a presente invenção descreve a produção de proteínas de ligação multiespec=íficas e multivalentes, os métodos de sua produção, e seus usos na prevenção, diagnósticos, e/ou tratamento de doenças.
BR112013004581A 2010-08-26 2011-08-25 imunoglobulinas de domínio variável dual e seus usos BR112013004581A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37711710P 2010-08-26 2010-08-26
PCT/US2011/049147 WO2012027570A2 (en) 2010-08-26 2011-08-25 Dual variable domain immunoglobulins and uses thereof

Publications (1)

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BR112013004581A2 true BR112013004581A2 (pt) 2017-06-27

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BR112013004581A BR112013004581A2 (pt) 2010-08-26 2011-08-25 imunoglobulinas de domínio variável dual e seus usos

Country Status (21)

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US (2) US9046513B2 (pt)
EP (1) EP2608803A4 (pt)
JP (1) JP2013539364A (pt)
KR (1) KR20130139884A (pt)
CN (1) CN103260639A (pt)
AR (1) AR082739A1 (pt)
AU (2) AU2011293253B2 (pt)
BR (1) BR112013004581A2 (pt)
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