MX2010006800A - 5-anilinoimidazopiridinas y metodos de uso de las mismas. - Google Patents

5-anilinoimidazopiridinas y metodos de uso de las mismas.

Info

Publication number
MX2010006800A
MX2010006800A MX2010006800A MX2010006800A MX2010006800A MX 2010006800 A MX2010006800 A MX 2010006800A MX 2010006800 A MX2010006800 A MX 2010006800A MX 2010006800 A MX2010006800 A MX 2010006800A MX 2010006800 A MX2010006800 A MX 2010006800A
Authority
MX
Mexico
Prior art keywords
methods
imidazopyridines
treating
relates
anilinoimidazopyridines
Prior art date
Application number
MX2010006800A
Other languages
English (en)
Inventor
Wendy Lee
Stephen Price
Robert Heald
Mark E Zak
Joanne Frances Mary Hewitt
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2010006800A publication Critical patent/MX2010006800A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Abstract

La invención es concerniente con imidazopiridinas de fórmula I con actividad anti-cáncer y/o anti-inflamatoria y más especialmente con imidazopiridinas que inhiben la actividad de cinasa MEK. La invención provee composiciones y métodos útiles para la inhibición del crecimiento anormal de células o tratamiento de enfermedad inflamatoria en un mamífero. La invención también es concerniente con métodos de uso de los compuestos para la diagnosis o tratamiento in vitro, in situ e in vivo de células mamíferas o condiciones patológicas asociadas.
MX2010006800A 2007-12-19 2008-12-18 5-anilinoimidazopiridinas y metodos de uso de las mismas. MX2010006800A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1512907P 2007-12-19 2007-12-19
US5401408P 2008-05-16 2008-05-16
PCT/US2008/087482 WO2009085983A1 (en) 2007-12-19 2008-12-18 5-anilinoimidazopyridines and methods of use

Publications (1)

Publication Number Publication Date
MX2010006800A true MX2010006800A (es) 2010-10-05

Family

ID=40350172

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010006800A MX2010006800A (es) 2007-12-19 2008-12-18 5-anilinoimidazopiridinas y metodos de uso de las mismas.

Country Status (28)

Country Link
US (4) US7923456B2 (es)
EP (2) EP2222675B1 (es)
JP (1) JP5421925B2 (es)
KR (1) KR101195329B1 (es)
CN (1) CN101945870B (es)
AR (1) AR069803A1 (es)
AU (1) AU2008343065B2 (es)
BR (1) BRPI0819529A2 (es)
CA (1) CA2706571C (es)
CL (1) CL2008003810A1 (es)
CY (2) CY1114663T1 (es)
DK (2) DK2690101T3 (es)
ES (2) ES2437141T3 (es)
HK (2) HK1147254A1 (es)
HR (1) HRP20151002T1 (es)
HU (1) HUE025192T2 (es)
IL (1) IL205977A (es)
MX (1) MX2010006800A (es)
MY (1) MY158829A (es)
NZ (1) NZ586802A (es)
PE (2) PE20131210A1 (es)
PL (2) PL2222675T3 (es)
PT (2) PT2690101E (es)
RU (1) RU2441004C1 (es)
SI (2) SI2690101T1 (es)
TW (1) TWI441820B (es)
WO (1) WO2009085983A1 (es)
ZA (1) ZA201003625B (es)

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