PT2880035T - Novos compostos de pirrolopirimidina como inibidores de proteína-cinases - Google Patents

Novos compostos de pirrolopirimidina como inibidores de proteína-cinases

Info

Publication number
PT2880035T
PT2880035T PT137454914T PT13745491T PT2880035T PT 2880035 T PT2880035 T PT 2880035T PT 137454914 T PT137454914 T PT 137454914T PT 13745491 T PT13745491 T PT 13745491T PT 2880035 T PT2880035 T PT 2880035T
Authority
PT
Portugal
Prior art keywords
inhibitors
protein kinases
pyrrolopyrimidine compounds
novel pyrrolopyrimidine
novel
Prior art date
Application number
PT137454914T
Other languages
English (en)
Inventor
Xu Xiao
Wang Xiaobo
Mao Long
Zhao Li
Xi Biao
Original Assignee
Acea Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/843,554 external-priority patent/US9034885B2/en
Application filed by Acea Biosciences Inc filed Critical Acea Biosciences Inc
Publication of PT2880035T publication Critical patent/PT2880035T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
PT137454914T 2012-08-06 2013-07-11 Novos compostos de pirrolopirimidina como inibidores de proteína-cinases PT2880035T (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261680231P 2012-08-06 2012-08-06
US13/843,554 US9034885B2 (en) 2012-01-13 2013-03-15 EGFR modulators and uses thereof
US201361814147P 2013-04-19 2013-04-19
US13/917,514 US8685988B2 (en) 2012-08-06 2013-06-13 EGFR modulators and uses thereof

Publications (1)

Publication Number Publication Date
PT2880035T true PT2880035T (pt) 2017-03-10

Family

ID=50068479

Family Applications (1)

Application Number Title Priority Date Filing Date
PT137454914T PT2880035T (pt) 2012-08-06 2013-07-11 Novos compostos de pirrolopirimidina como inibidores de proteína-cinases

Country Status (22)

Country Link
EP (2) EP2880035B9 (pt)
JP (2) JP6215938B2 (pt)
KR (1) KR102181365B1 (pt)
CN (2) CN103748096B (pt)
AU (1) AU2013300106B2 (pt)
BR (1) BR112015002709B1 (pt)
CA (1) CA2881275C (pt)
CY (1) CY1120844T1 (pt)
DK (1) DK2880035T3 (pt)
ES (2) ES2618007T3 (pt)
HK (1) HK1210471A1 (pt)
HR (1) HRP20170311T1 (pt)
HU (1) HUE031955T2 (pt)
IN (1) IN2015DN00914A (pt)
LT (1) LT2880035T (pt)
MX (1) MX361992B (pt)
NZ (1) NZ629807A (pt)
PT (1) PT2880035T (pt)
RU (2) RU2645672C2 (pt)
SG (1) SG11201500872SA (pt)
WO (1) WO2014025486A1 (pt)
ZA (2) ZA201500762B (pt)

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Also Published As

Publication number Publication date
HK1210471A1 (en) 2016-04-22
ZA201500762B (en) 2021-09-29
RU2015107831A (ru) 2016-09-27
KR102181365B1 (ko) 2020-11-23
CN103748096B (zh) 2017-10-20
RU2645672C2 (ru) 2018-02-27
JP2015524468A (ja) 2015-08-24
HUE031955T2 (en) 2017-08-28
SG11201500872SA (en) 2015-03-30
IN2015DN00914A (pt) 2015-06-12
EP2880035B1 (en) 2016-12-07
RU2018104702A (ru) 2019-02-22
NZ629807A (en) 2017-04-28
AU2013300106A1 (en) 2015-02-19
CN107266453B (zh) 2020-02-07
EP3170825A1 (en) 2017-05-24
EP2880035A1 (en) 2015-06-10
JP2017061581A (ja) 2017-03-30
AU2013300106B2 (en) 2017-11-30
ES2618007T3 (es) 2017-06-20
CN107266453A (zh) 2017-10-20
EP2880035B9 (en) 2017-05-17
MX2015001715A (es) 2015-07-06
BR112015002709A2 (pt) 2017-07-04
DK2880035T3 (en) 2017-03-06
CN103748096A (zh) 2014-04-23
CA2881275A1 (en) 2014-02-13
JP6215938B2 (ja) 2017-10-18
CY1120844T1 (el) 2019-12-11
WO2014025486A1 (en) 2014-02-13
HRP20170311T1 (hr) 2017-04-21
CA2881275C (en) 2020-10-20
ZA201600648B (en) 2021-09-29
LT2880035T (lt) 2017-03-27
BR112015002709B1 (pt) 2022-09-20
KR20150068949A (ko) 2015-06-22
ES2733576T3 (es) 2019-12-02
MX361992B (es) 2018-12-19
EP3170825B1 (en) 2019-04-10

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