SI2342226T1 - Humana protitelesa proti PD-1, PD-L1 in PD-L2 in njihove uporabe - Google Patents

Humana protitelesa proti PD-1, PD-L1 in PD-L2 in njihove uporabe

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Publication number
SI2342226T1
SI2342226T1 SI200931522A SI200931522A SI2342226T1 SI 2342226 T1 SI2342226 T1 SI 2342226T1 SI 200931522 A SI200931522 A SI 200931522A SI 200931522 A SI200931522 A SI 200931522A SI 2342226 T1 SI2342226 T1 SI 2342226T1
Authority
SI
Slovenia
Prior art keywords
antibodies
human anti
human
Prior art date
Application number
SI200931522A
Other languages
English (en)
Inventor
Gordon J. Freeman
Rafi Ahmed
Timothy D. Jones
Francis J. Carr
James P. Gregson
Original Assignee
Dana-Farber Cancer Institute Inc.
Emory University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana-Farber Cancer Institute Inc., Emory University filed Critical Dana-Farber Cancer Institute Inc.
Publication of SI2342226T1 publication Critical patent/SI2342226T1/sl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • C—CHEMISTRY; METALLURGY
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    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
SI200931522A 2008-09-26 2009-09-25 Humana protitelesa proti PD-1, PD-L1 in PD-L2 in njihove uporabe SI2342226T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10053408P 2008-09-26 2008-09-26
EP09816950.1A EP2342226B1 (en) 2008-09-26 2009-09-25 Human anti-pd-1, pd-l1, and pd-l2 antibodies and uses thereof
PCT/US2009/058475 WO2010036959A2 (en) 2008-09-26 2009-09-25 Human anti-pd-1, pd-l1, and pd-l2 antibodies and uses therefor

Publications (1)

Publication Number Publication Date
SI2342226T1 true SI2342226T1 (sl) 2016-11-30

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ID=42060416

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200931522A SI2342226T1 (sl) 2008-09-26 2009-09-25 Humana protitelesa proti PD-1, PD-L1 in PD-L2 in njihove uporabe

Country Status (16)

Country Link
US (5) US8552154B2 (sl)
EP (3) EP3530672A1 (sl)
JP (4) JP6087503B2 (sl)
KR (4) KR102097887B1 (sl)
CN (2) CN102264762B (sl)
AU (4) AU2009296392B2 (sl)
BR (1) BRPI0919377A2 (sl)
CA (2) CA2738252C (sl)
DK (1) DK2342226T3 (sl)
ES (1) ES2592216T3 (sl)
HU (1) HUE030807T2 (sl)
IL (3) IL211830A (sl)
MX (2) MX2011003195A (sl)
PL (1) PL2342226T3 (sl)
SI (1) SI2342226T1 (sl)
WO (1) WO2010036959A2 (sl)

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WO2009137807A2 (en) 2008-05-08 2009-11-12 Asuragen, Inc. Compositions and methods related to mirna modulation of neovascularization or angiogenesis
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US10016617B2 (en) 2009-11-11 2018-07-10 The Trustees Of The University Of Pennsylvania Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers
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