SG11201400513PA
(en)
|
2011-09-08 |
2014-06-27 |
Yeda Res & Dev |
Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment
|
BR112015002816A8
(pt)
|
2012-08-20 |
2023-04-18 |
Hutchinson Fred Cancer Res |
Método e composições para imunoterapia celular
|
TW201446794A
(zh)
|
2013-02-20 |
2014-12-16 |
Novartis Ag |
利用抗-cd123嵌合抗原受體工程化t細胞之初級人類白血病有效靶向
|
ES2760023T3
(es)
|
2013-02-20 |
2020-05-12 |
Univ Pennsylvania |
Tratamiento del cáncer utilizando receptor de antígeno quimérico anti-EGFRvIII humanizado
|
WO2014145252A2
(en)
|
2013-03-15 |
2014-09-18 |
Milone Michael C |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
TWI654206B
(zh)
|
2013-03-16 |
2019-03-21 |
諾華公司 |
使用人類化抗-cd19嵌合抗原受體治療癌症
|
EP3083964B1
(en)
|
2013-12-19 |
2022-01-26 |
Novartis AG |
Human mesothelin chimeric antigen receptors and uses thereof
|
EP3087101A4
(en)
|
2013-12-20 |
2017-12-06 |
Novartis AG |
Regulatable chimeric antigen receptor
|
ES2963718T3
(es)
|
2014-01-21 |
2024-04-01 |
Novartis Ag |
Capacidad presentadora de antígenos de células CAR-T potenciada mediante introducción conjunta de moléculas co-estimuladoras
|
KR102487608B1
(ko)
|
2014-04-07 |
2023-01-12 |
노파르티스 아게 |
항-cd19 키메라 항원 수용체를 사용한 암의 치료
|
MX2016013158A
(es)
*
|
2014-04-10 |
2017-04-27 |
Seattle Children's Hospital (Dba Seattle Children's Res Institute) |
Productos de celulas t modificadas de genes de composicion definida.
|
SI3132247T1
(sl)
|
2014-04-16 |
2021-12-31 |
Juno Therapeutics Gmbh |
Postopki, kompleti in naprava za povečanje populacije celic
|
EP3134514B1
(en)
|
2014-04-23 |
2019-09-18 |
Juno Therapeutics, Inc. |
Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy
|
IL296691B2
(en)
|
2014-04-25 |
2023-11-01 |
2Seventy Bio Inc |
MND promoter chimeric antigen receptors
|
SG11201610170SA
(en)
|
2014-06-06 |
2017-01-27 |
Bluebird Bio Inc |
Improved t cell compositions
|
CN107075483A
(zh)
|
2014-07-15 |
2017-08-18 |
朱诺治疗学股份有限公司 |
用于过继细胞治疗的工程改造的细胞
|
CA2955386A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Treatment of cancer using humanized anti-bcma chimeric antigen receptor
|
EP3171882A1
(en)
|
2014-07-21 |
2017-05-31 |
Novartis AG |
Treatment of cancer using a cll-1 chimeric antigen receptor
|
WO2016014553A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
TWI719942B
(zh)
|
2014-07-21 |
2021-03-01 |
瑞士商諾華公司 |
使用cd33嵌合抗原受體治療癌症
|
CN113846062A
(zh)
*
|
2014-07-25 |
2021-12-28 |
赛拉福柯蒂斯公司 |
用于嵌合抗原受体分子的调控表达的慢病毒载体
|
EP3453406B1
(en)
|
2014-07-29 |
2021-04-14 |
Cellectis |
Ror1 (ntrkr1) specific chimeric antigen receptors for cancer immunotherapy
|
US10544201B2
(en)
|
2014-07-31 |
2020-01-28 |
Cellectis |
ROR1 specific multi-chain chimeric antigen receptor
|
CN112410363A
(zh)
|
2014-08-19 |
2021-02-26 |
诺华股份有限公司 |
抗cd123嵌合抗原受体(car)用于癌症治疗
|
CN106661129B
(zh)
*
|
2014-08-19 |
2021-02-05 |
美天施生物科技有限两合公司 |
对ssea4抗原具有特异性的嵌合抗原受体
|
TWI805109B
(zh)
|
2014-08-28 |
2023-06-11 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
ES2777305T3
(es)
|
2014-09-04 |
2020-08-04 |
Cellectis |
Receptores de antígeno quiméricos específicos de la glicoproteína trofoblástica (5T4, TPBG) para inmunoterapia contra el cáncer
|
ES2891332T3
(es)
|
2014-09-17 |
2022-01-27 |
Novartis Ag |
Direccionamiento a células citotóxicas con receptores quiméricos para la inmunoterapia adoptiva
|
BR122024000360A2
(pt)
*
|
2014-09-19 |
2024-02-27 |
City Of Hope |
Molécula de ácido nucleico, população de células t humanas transduzidas por um vetor que compreende um cassete de expressão que codifica um receptor de antígeno quimérico e seu uso
|
EP3204777A1
(en)
|
2014-10-08 |
2017-08-16 |
Novartis AG |
Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
|
MX2017005106A
(es)
|
2014-10-20 |
2017-07-05 |
Juno Therapeutics Inc |
Metodos y composiciones para dosificacion en terapia celular adoptiva.
|
EP3215601B1
(en)
|
2014-11-05 |
2020-05-27 |
Juno Therapeutics, Inc. |
Methods for transduction and cell processing
|
WO2016090034A2
(en)
|
2014-12-03 |
2016-06-09 |
Novartis Ag |
Methods for b cell preconditioning in car therapy
|
KR20170087514A
(ko)
|
2014-12-03 |
2017-07-28 |
주노 쎄러퓨티크스 인코퍼레이티드 |
입양 세포 치료를 위한 방법 및 조성물
|
KR102584938B1
(ko)
|
2014-12-12 |
2023-10-05 |
2세븐티 바이오, 인코포레이티드 |
Bcma 키메릭 항원 수용체
|
WO2016094873A2
(en)
*
|
2014-12-12 |
2016-06-16 |
Emergent Product Development Seattle, Llc |
Receptor tyrosine kinase-like orphan receptor 1 binding proteins and related compositions and methods
|
US10273300B2
(en)
|
2014-12-29 |
2019-04-30 |
The Trustees Of The University Of Pennsylvania |
Methods of making chimeric antigen receptor-expressing cells
|
MA41346A
(fr)
|
2015-01-12 |
2017-11-21 |
Juno Therapeutics Inc |
Eléments régulateurs post-transcriptionnels d'hépatite modifiée
|
CA2973964A1
(en)
|
2015-01-16 |
2016-07-21 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for ror1
|
US11459390B2
(en)
|
2015-01-16 |
2022-10-04 |
Novartis Ag |
Phosphoglycerate kinase 1 (PGK) promoters and methods of use for expressing chimeric antigen receptor
|
WO2016126608A1
(en)
|
2015-02-02 |
2016-08-11 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
CN105985444B
(zh)
*
|
2015-02-05 |
2024-02-13 |
博生吉安科细胞技术有限公司 |
一种嵌合抗原受体、以及快速构建嵌合抗原受体的方法及应用
|
HUE059218T2
(hu)
|
2015-04-08 |
2022-11-28 |
Novartis Ag |
CD20-terápiák, CD22-terápiák és kombinációs terápiák CD19 kiméra antigénreceptort (CAR-t) expresszáló sejttel
|
WO2016166568A1
(en)
|
2015-04-16 |
2016-10-20 |
Juno Therapeutics Gmbh |
Methods, kits and apparatus for expanding a population of cells
|
ES2948133T3
(es)
|
2015-04-17 |
2023-08-31 |
Novartis Ag |
Métodos para mejorar la eficacia y expansión de células que expresan un receptor de antígeno quimérico
|
EP3288570A4
(en)
|
2015-04-29 |
2018-11-21 |
Fred Hutchinson Cancer Research Center |
Modified stem cells and uses thereof
|
AU2016257721B2
(en)
|
2015-05-01 |
2019-11-14 |
The Regents Of The University Of California |
Glycan-dependent immunotherapeutic molecules
|
CA2986254A1
(en)
*
|
2015-05-18 |
2016-11-24 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
TW201706300A
(zh)
|
2015-05-20 |
2017-02-16 |
瑟勒提斯公司 |
用於癌症免疫療法之抗-gd3專一性嵌合抗原受體
|
WO2016196384A1
(en)
|
2015-05-29 |
2016-12-08 |
Fred Hutchinson Cancer Research Center |
Compositions for cellular immunotherapy
|
JP6949728B2
(ja)
|
2015-05-29 |
2021-10-13 |
ジュノー セラピューティクス インコーポレイテッド |
遺伝子操作された細胞における阻害相互作用を調節するための組成物および方法
|
MA42895A
(fr)
|
2015-07-15 |
2018-05-23 |
Juno Therapeutics Inc |
Cellules modifiées pour thérapie cellulaire adoptive
|
EP3322424B1
(en)
|
2015-07-16 |
2023-10-11 |
Yeda Research and Development Co., Ltd. |
Use of anti third party central memory t cells
|
EP3324984A4
(en)
*
|
2015-07-21 |
2019-03-27 |
City of Hope |
T CELLS FOR THE EXPRESSION OF CHIMERIC ANTIGEN RECEPTORS AND OTHER RECEPTORS
|
AU2016297014B2
(en)
|
2015-07-21 |
2021-06-17 |
Novartis Ag |
Methods for improving the efficacy and expansion of immune cells
|
WO2017023803A1
(en)
|
2015-07-31 |
2017-02-09 |
Regents Of The University Of Minnesota |
Modified cells and methods of therapy
|
US11667691B2
(en)
|
2015-08-07 |
2023-06-06 |
Novartis Ag |
Treatment of cancer using chimeric CD3 receptor proteins
|
CN108174604B
(zh)
*
|
2015-08-07 |
2023-06-23 |
西雅图儿童医院(Dba西雅图儿童研究所) |
用于实体瘤靶向的双特异性car t细胞
|
CN106467906B
(zh)
*
|
2015-08-20 |
2019-09-27 |
北京马力喏生物科技有限公司 |
构建体、转基因淋巴细胞及其制备方法和用途
|
KR20180037294A
(ko)
*
|
2015-08-31 |
2018-04-11 |
블루버드 바이오, 인코포레이티드. |
항-시알릴 Tn 키메라 항원 수용체
|
US11747346B2
(en)
|
2015-09-03 |
2023-09-05 |
Novartis Ag |
Biomarkers predictive of cytokine release syndrome
|
AU2016318773A1
(en)
|
2015-09-09 |
2018-04-12 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Genetic engineering of macrophages for immunotherapy
|
KR20180049080A
(ko)
*
|
2015-09-11 |
2018-05-10 |
더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 |
생물학적으로 관련된 직교 사이토카인/수용체 쌍
|
EP3662930A1
(en)
|
2015-09-24 |
2020-06-10 |
AbVitro LLC |
Hiv antibody compositions and methods of use
|
EP3353550A1
(en)
|
2015-09-25 |
2018-08-01 |
AbVitro LLC |
High throughput process for t cell receptor target identification of natively-paired t cell receptor sequences
|
BR112018006991A2
(pt)
*
|
2015-10-06 |
2018-10-16 |
Hope City |
receptores de antígeno quiméricos direcionados ao psca
|
RU2021134624A
(ru)
|
2015-10-22 |
2022-03-15 |
Джуно Терапьютикс Гмбх |
Способы, наборы, средства и устройства для трансдукции
|
MA45488A
(fr)
|
2015-10-22 |
2018-08-29 |
Juno Therapeutics Gmbh |
Procédés, kits et appareil de culture de cellules
|
MA45489A
(fr)
|
2015-10-22 |
2018-08-29 |
Juno Therapeutics Gmbh |
Procédés de culture de cellules, kits et appareil associés
|
EP3368051A4
(en)
|
2015-10-30 |
2019-06-26 |
Children's National Medical Center |
GENERATION OF HPV ANTIGEN-SPECIFIC T CELLS FROM A NAIVEN T CELL POPULATION
|
SG11201803098VA
(en)
|
2015-10-30 |
2018-05-30 |
Nbe Therapeutics Ag |
Anti-ror1 antibodies
|
CN108779174B
(zh)
*
|
2015-11-04 |
2022-11-29 |
希望之城公司 |
靶向her2的嵌合抗原受体
|
US11020429B2
(en)
|
2015-11-05 |
2021-06-01 |
Juno Therapeutics, Inc. |
Vectors and genetically engineered immune cells expressing metabolic pathway modulators and uses in adoptive cell therapy
|
MA44314A
(fr)
|
2015-11-05 |
2018-09-12 |
Juno Therapeutics Inc |
Récepteurs chimériques contenant des domaines induisant traf, et compositions et méthodes associées
|
WO2017096329A1
(en)
|
2015-12-03 |
2017-06-08 |
Juno Therapeutics, Inc. |
Modified chimeric receptors and related compositions and methods
|
CA3007258A1
(en)
|
2015-12-03 |
2017-06-08 |
Mark L. Bonyhadi |
Compositions and methods for reducing immune responses against cell therapies
|
MA43377A
(fr)
|
2015-12-04 |
2021-05-19 |
Hutchinson Fred Cancer Res |
Méthodes et compositions liées à la toxicité associée à la thérapie cellulaire
|
WO2017099712A1
(en)
|
2015-12-07 |
2017-06-15 |
Bluebird Bio, Inc. |
Improved t cell compositions
|
MA44140A
(fr)
|
2015-12-22 |
2021-05-19 |
Dana Farber Cancer Inst Inc |
Récepteur d'antigène chimérique (car) contre la mésothéline et anticorps contre l'inhibiteur de pd-l1 pour une utilisation combinée dans une thérapie anticancéreuse
|
RU2018127657A
(ru)
|
2015-12-30 |
2020-01-31 |
Новартис Аг |
Виды терапии на основе иммуноэффекторных клеток с улучшенной эффективностью
|
WO2017123956A1
(en)
*
|
2016-01-15 |
2017-07-20 |
Etubics Corporation |
Methods and compositions for t-cell immunotherapy
|
CN106978442B
(zh)
*
|
2016-01-18 |
2020-06-19 |
爱康得生物医学技术(苏州)有限公司 |
一种嵌合抗原受体t细胞的制备方法
|
BR112018014615A2
(pt)
|
2016-01-20 |
2018-12-11 |
The Scripps Research Institute |
composições de anticorpo para ror1 e métodos relacionados
|
US10968275B2
(en)
|
2016-02-02 |
2021-04-06 |
Fred Hutchinson Cancer Research Center |
Anti-ROR1 antibodies and uses thereof
|
SG11201807489PA
(en)
|
2016-03-04 |
2018-09-27 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
|
EP3430549A1
(en)
|
2016-03-16 |
2019-01-23 |
Juno Therapeutics, Inc. |
Methods for adaptive design of a treatment regimen and related treatments
|
EP3430548A1
(en)
|
2016-03-16 |
2019-01-23 |
Juno Therapeutics, Inc. |
Methods for determining dosing of a therapeutic agent and related treatments
|
CN108884144B
(zh)
|
2016-03-18 |
2023-03-14 |
弗雷德哈钦森癌症中心 |
用于cd20免疫疗法的组合物和方法
|
AU2017238218A1
(en)
|
2016-03-22 |
2018-10-11 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Early intervention methods to prevent or ameliorate toxicity
|
EP3432924A1
(en)
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Cell secreted minibodies and uses thereof
|
JP2019509753A
(ja)
*
|
2016-03-31 |
2019-04-11 |
ライオン ティーシーアール ピーティーイー.エルティーディー. |
外因性ウイルス特異的t細胞受容体(tcr)を発現する非活性化t細胞
|
WO2017181119A2
(en)
|
2016-04-15 |
2017-10-19 |
Novartis Ag |
Compositions and methods for selective protein expression
|
US11963980B2
(en)
|
2016-04-25 |
2024-04-23 |
Musc Foundation For Research Development |
Activated CD26-high immune cells and CD26-negative immune cells and uses thereof
|
SG11201809710RA
(en)
|
2016-05-06 |
2018-11-29 |
Juno Therapeutics Inc |
Genetically engineered cells and methods of making the same
|
AU2017268842B2
(en)
|
2016-05-27 |
2022-08-11 |
Aadigen, Llc |
Peptides and nanoparticles for intracellular delivery of genome-editing molecules
|
EP3463401A4
(en)
|
2016-06-03 |
2020-01-22 |
Memorial Sloan Kettering Cancer Center |
ADOPTIVE CELL THERAPIES AS EARLY TREATMENT OPTIONS
|
MA45341A
(fr)
|
2016-06-06 |
2019-04-10 |
Hutchinson Fred Cancer Res |
Procédés de traitement de malignités de lymphocytes b au moyen d'une thérapie cellulaire adoptive
|
JP2019527537A
(ja)
*
|
2016-06-07 |
2019-10-03 |
マックス−デルブリュック−セントルム フュール モレキュラー メディツィン イン デア ヘルムホルツ−ゲマインシャフト |
キメラ抗原受容体と、bcmaに結合するcar−t細胞
|
CN107522786A
(zh)
*
|
2016-06-20 |
2017-12-29 |
深圳市体内生物医药科技有限公司 |
一种分子、表达其的细胞及其制备方法和用途
|
JPWO2017221850A1
(ja)
*
|
2016-06-21 |
2019-05-23 |
国立大学法人名古屋大学 |
T細胞機能向上のためのアダプター分子
|
CA3028002A1
(en)
|
2016-06-27 |
2018-01-04 |
Juno Therapeutics, Inc. |
Method of identifying peptide epitopes, molecules that bind such epitopes and related uses
|
MA45491A
(fr)
|
2016-06-27 |
2019-05-01 |
Juno Therapeutics Inc |
Épitopes à restriction cmh-e, molécules de liaison et procédés et utilisations associés
|
EP3484516A4
(en)
*
|
2016-07-14 |
2020-03-18 |
Fred Hutchinson Cancer Research Center |
MULTIPLE CONSTRUCTIONS OF BI-SPECIFIC LINK AREAS HAVING A DIFFERENT EPITOPE LINK TO TREAT CANCER
|
MX2019001184A
(es)
|
2016-07-29 |
2019-09-26 |
Juno Therapeutics Inc |
Anticuerpos anti-idiotípicos y métodos relacionados.
|
WO2018023093A1
(en)
|
2016-07-29 |
2018-02-01 |
Juno Therapeutics, Inc. |
Immunomodulatory polypeptides and related compositions and methods
|
MA45783A
(fr)
|
2016-07-29 |
2019-06-05 |
Juno Therapeutics Inc |
Procédés d'évaluation de la présence ou de l'absence d'un virus compétent pour la réplication
|
US20190161542A1
(en)
|
2016-08-01 |
2019-05-30 |
Novartis Ag |
Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule
|
JP7109789B2
(ja)
|
2016-08-02 |
2022-08-01 |
ティーシーアール2 セラピューティクス インク. |
融合タンパク質を使用したtcrの再プログラム化のための組成物及び方法
|
MX2019002765A
(es)
|
2016-09-12 |
2019-05-09 |
Juno Therapeutics Inc |
Montajes de bolsa de biorreactor de perfusion.
|
CA3035075A1
(en)
|
2016-09-23 |
2018-03-29 |
Fred Hutchinson Cancer Research Center |
Tcrs specific for minor histocompatibility (h) antigen ha-1 and uses thereof
|
EP4089116A1
(en)
|
2016-09-27 |
2022-11-16 |
Cero Therapeutics, Inc. |
Chimeric engulfment receptor molecules
|
EP4353319A2
(en)
|
2016-09-28 |
2024-04-17 |
Atossa Therapeutics, Inc. |
Methods of adoptive cell therapy
|
MX2019003768A
(es)
|
2016-10-03 |
2019-06-24 |
Juno Therapeutics Inc |
Moleculas de enlace especificas de hpv.
|
EP3523331A1
(en)
|
2016-10-07 |
2019-08-14 |
Novartis AG |
Chimeric antigen receptors for the treatment of cancer
|
MX2019003899A
(es)
|
2016-10-07 |
2019-08-14 |
Tcr2 Therapeutics Inc |
Composiciones y metodos para reprogramacion de receptores de linfocitos t mediante el uso de proteinas de fusion.
|
JP2019533676A
(ja)
|
2016-10-13 |
2019-11-21 |
ジュノー セラピューティクス インコーポレイテッド |
トリプトファン代謝経路調節剤を含む免疫療法の方法および組成物
|
GB2605540B
(en)
|
2016-10-18 |
2022-12-21 |
Univ Minnesota |
Tumor infiltrating lymphocytes and methods of therapy
|
EP3532497A4
(en)
*
|
2016-10-26 |
2020-05-13 |
The Board of Trustees of the Leland Stanford Junior University |
MODIFIED IMMUNOGLOBULIN BAND REGIONS TO REDUCE HEMAGGLUTINATION
|
JP2019532997A
(ja)
*
|
2016-11-03 |
2019-11-14 |
ジュノー セラピューティクス インコーポレイテッド |
T細胞療法とbtk阻害剤との併用療法
|
WO2018093591A1
(en)
|
2016-11-03 |
2018-05-24 |
Juno Therapeutics, Inc. |
Combination therapy of a cell based therapy and a microglia inhibitor
|
CN110177803A
(zh)
|
2016-11-22 |
2019-08-27 |
T细胞受体治疗公司 |
用于使用融合蛋白进行tcr重新编程的组合物和方法
|
EP3548622A1
(en)
|
2016-12-02 |
2019-10-09 |
Juno Therapeutics, Inc. |
Engineered b cells and related compositions and methods
|
CN110248678A
(zh)
|
2016-12-03 |
2019-09-17 |
朱诺治疗学股份有限公司 |
调节car-t细胞的方法
|
US20200078400A1
(en)
|
2016-12-03 |
2020-03-12 |
Juno Therapeutics, Inc. |
Methods for determining car-t cells dosing
|
US11590167B2
(en)
|
2016-12-03 |
2023-02-28 |
Juno Therapeutic, Inc. |
Methods and compositions for use of therapeutic T cells in combination with kinase inhibitors
|
WO2018106732A1
(en)
|
2016-12-05 |
2018-06-14 |
Juno Therapeutics, Inc. |
Production of engineered cells for adoptive cell therapy
|
MX2019006631A
(es)
|
2016-12-12 |
2019-11-12 |
Seattle Childrens Hospital Dba Seattle Childrens Res Inst |
Variantes quimericas de factores de transcripcion con sensibilidad aumentada a induccion por ligando de farmaco de expresion transgenica en celulas mamiferas.
|
EP4183798A1
(en)
*
|
2017-01-09 |
2023-05-24 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-mesothelin immunotherapy
|
JP7429338B2
(ja)
|
2017-01-10 |
2024-02-08 |
ジュノー セラピューティクス インコーポレイテッド |
細胞療法および関連方法のエピジェネティック解析
|
US11541076B2
(en)
|
2017-01-13 |
2023-01-03 |
Celdara Medical, Llc |
Chimeric antigen receptors targeting TIM-1
|
EP3570850A4
(en)
*
|
2017-01-18 |
2020-10-14 |
Thalia Papayannopoulou |
COMPOSITIONS AND PROCEDURES FOR CONDITIONING TRANSPLANT RECIPIENTS
|
CN110392736A
(zh)
|
2017-01-18 |
2019-10-29 |
耶达研究及发展有限公司 |
遗传修饰的反抑细胞及其在免疫治疗中的用途
|
US11517627B2
(en)
|
2017-01-20 |
2022-12-06 |
Juno Therapeutics Gmbh |
Cell surface conjugates and related cell compositions and methods
|
ES2912408T3
(es)
|
2017-01-26 |
2022-05-25 |
Novartis Ag |
Composiciones de CD28 y métodos para terapia con receptores quiméricos para antígenos
|
RU2674894C2
(ru)
*
|
2017-01-30 |
2018-12-13 |
Общество с ограниченной ответственностью "ПЛАНТА" |
Новые люциферазы и способы их использования
|
EP3579870A4
(en)
|
2017-02-07 |
2020-12-30 |
Seattle Children's Hospital (DBA Seattle Children's Research Institute) |
PHOSPHOLIPID ETHER (PLE) T CAR-LYMPHOCYTE TUMOR (CTCT) TARGETING AGENTS
|
ES2949364T3
(es)
|
2017-02-17 |
2023-09-28 |
Fred Hutchinson Cancer Center |
Terapias de combinación para el tratamiento de cánceres y trastornos autoinmunitarios relacionados con BCMA
|
EP4353818A2
(en)
|
2017-02-27 |
2024-04-17 |
Juno Therapeutics, Inc. |
Compositions, articles of manufacture and methods related to dosing in cell therapy
|
CN110582288A
(zh)
|
2017-02-28 |
2019-12-17 |
恩多塞特公司 |
用于car t细胞疗法的组合物和方法
|
SG11201908271WA
(en)
|
2017-03-14 |
2019-10-30 |
Juno Therapeutics Inc |
Methods for cryogenic storage
|
MX2019010972A
(es)
|
2017-03-15 |
2019-12-02 |
Hutchinson Fred Cancer Res |
Receptores de linfocito t (tcr) específicos del antígeno asociado a melanoma 1 (mage-a1) de alta afinidad y usos de estos.
|
EP3595705A1
(en)
|
2017-03-15 |
2020-01-22 |
Oxford BioMedica (UK) Limited |
Method
|
BR112019018124A2
(pt)
|
2017-03-22 |
2020-04-07 |
Intellia Therapeutics Inc |
composições e métodos para imunooncologia
|
JP7284707B2
(ja)
|
2017-04-07 |
2023-05-31 |
ジュノー セラピューティクス インコーポレイテッド |
前立腺特異的膜抗原(psma)またはその改変型を発現する操作された細胞および関連方法
|
JP7355650B2
(ja)
|
2017-04-14 |
2023-10-03 |
ジュノー セラピューティクス インコーポレイテッド |
細胞表面グリコシル化を評価するための方法
|
US20200123501A1
(en)
|
2017-04-18 |
2020-04-23 |
FUJIFILM Cellular Dynamics, Inc. |
Antigen-specific immune effector cells
|
AU2018260380A1
(en)
|
2017-04-27 |
2019-11-07 |
Juno Therapeutics Gmbh |
Oligomeric particle reagents and methods of use thereof
|
WO2018204427A1
(en)
|
2017-05-01 |
2018-11-08 |
Juno Therapeutics, Inc. |
Combination of a cell therapy and an immunomodulatory compound
|
WO2018213332A1
(en)
*
|
2017-05-17 |
2018-11-22 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Generating mammalian t cell activation inducible synthetic promoters (syn+pro) to improve t cell therapy
|
CA3064000A1
(en)
|
2017-05-24 |
2018-11-29 |
Effector Therapeutics, Inc. |
Methods and compositions for cellular immunotherapy
|
JP7158416B2
(ja)
|
2017-05-24 |
2022-10-21 |
イーフェクター セラピューティクス, インコーポレイテッド |
抗腫瘍免疫応答を改善するための組成物および方法
|
JP2020522489A
(ja)
|
2017-06-02 |
2020-07-30 |
ジュノー セラピューティクス インコーポレイテッド |
養子細胞療法を用いる処置のための製造物品および方法
|
EP3631468A1
(en)
|
2017-06-02 |
2020-04-08 |
Juno Therapeutics, Inc. |
Articles of manufacture and methods related to toxicity associated with cell therapy
|
WO2018234370A1
(en)
|
2017-06-20 |
2018-12-27 |
Institut Curie |
DEFECTIVE IMMUNE CELLS AGAINST SUV39H1
|
EP4302768A3
(en)
|
2017-06-22 |
2024-05-01 |
Board Of Regents, The University Of Texas System |
Methods for producing regulatory immune cells and uses thereof
|
AU2018291032A1
(en)
|
2017-06-29 |
2020-01-16 |
Juno Therapeutics, Inc. |
Mouse model for assessing toxicities associated with immunotherapies
|
JP2020530307A
(ja)
|
2017-06-30 |
2020-10-22 |
インティマ・バイオサイエンス,インコーポレーテッド |
遺伝子治療のためのアデノ随伴ウイルスベクター
|
GB201710835D0
(en)
|
2017-07-05 |
2017-08-16 |
Ucl Business Plc |
ROR1 Antibodies
|
GB201710838D0
(en)
|
2017-07-05 |
2017-08-16 |
Ucl Business Plc |
Bispecific antibodies
|
GB201710836D0
(en)
|
2017-07-05 |
2017-08-16 |
Ucl Business Plc |
ROR1 Car T-Cells
|
EP3661528A1
(en)
|
2017-07-29 |
2020-06-10 |
Juno Therapeutics, Inc. |
Reagents for expanding cells expressing recombinant receptors
|
CA3071212C
(en)
|
2017-08-07 |
2023-12-12 |
Nbe-Therapeutics Ag |
Anthracycline-based antibody drug conjugates having high in vivo tolerability
|
US20200239910A1
(en)
|
2017-08-09 |
2020-07-30 |
Juno Therapeutics, Inc. |
Methods and compositions for preparing genetically engineered cells
|
ES2959953T3
(es)
|
2017-08-09 |
2024-02-29 |
Juno Therapeutics Inc |
Métodos para producir composiciones celulares genéticamente modificadas y composiciones relacionadas
|
MA50057A
(fr)
|
2017-09-01 |
2020-07-08 |
Juno Therapeutics Inc |
Expression génique et évaluation d'un risque de développement d'une toxicité suite à une thérapie cellulaire
|
EP3678689A1
(en)
|
2017-09-06 |
2020-07-15 |
Fred Hutchinson Cancer Research Center |
Strep-tag specific binding proteins and uses thereof
|
EP3679072A1
(en)
|
2017-09-06 |
2020-07-15 |
Fred Hutchinson Cancer Research Center |
Strep-tag specific chimeric receptors and uses thereof
|
WO2019051135A1
(en)
|
2017-09-06 |
2019-03-14 |
Fred Hutchinson Cancer Research Center |
METHODS FOR IMPROVING ADOPTIVE CELL THERAPY
|
EP3679370A1
(en)
|
2017-09-07 |
2020-07-15 |
Juno Therapeutics, Inc. |
Methods of identifying cellular attributes related to outcomes associated with cell therapy
|
CN109517820B
(zh)
|
2017-09-20 |
2021-09-24 |
北京宇繁生物科技有限公司 |
一种靶向HPK1的gRNA以及HPK1基因编辑方法
|
CN107641615A
(zh)
*
|
2017-09-22 |
2018-01-30 |
苏州大学 |
一种小鼠胰腺内浸润的免疫细胞分离方法
|
MX2020007266A
(es)
|
2017-09-26 |
2020-09-07 |
Cero Therapeutics Inc |
Moleculas del receptor quimerico de engullido y metodos de uso.
|
AU2018345539A1
(en)
|
2017-10-03 |
2020-04-16 |
Editas Medicine, Inc. |
HPV-specific binding molecules
|
US11771718B2
(en)
|
2017-10-18 |
2023-10-03 |
Precigen, Inc. |
Polypeptide compositions comprising spacers
|
CN107759699A
(zh)
*
|
2017-10-18 |
2018-03-06 |
银丰生物工程集团有限公司 |
靶向cd30抗原的转基因t细胞及其制备方法与应用
|
EP3697435A1
(en)
|
2017-10-20 |
2020-08-26 |
Fred Hutchinson Cancer Research Center |
Compositions and methods of immunotherapy targeting tigit and/or cd112r or comprising cd226 overexpression
|
SG11202003862PA
(en)
|
2017-11-01 |
2020-05-28 |
Editas Medicine Inc |
Methods, compositions and components for crispr-cas9 editing of tgfbr2 in t cells for immunotherapy
|
SG11202003657VA
(en)
|
2017-11-01 |
2020-05-28 |
Juno Therapeutics Inc |
Process for producing a t cell composition
|
US20210132042A1
(en)
|
2017-11-01 |
2021-05-06 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
WO2019089848A1
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Methods associated with tumor burden for assessing response to a cell therapy
|
EP3703688A2
(en)
|
2017-11-01 |
2020-09-09 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for b-cell maturation antigen
|
KR20200116077A
(ko)
|
2017-11-01 |
2020-10-08 |
주노 쎄러퓨티크스 인코퍼레이티드 |
B 세포 성숙 항원에 특이적인 키메라 항원 수용체 및 암호화 폴리뉴클레오타이드
|
US11851679B2
(en)
|
2017-11-01 |
2023-12-26 |
Juno Therapeutics, Inc. |
Method of assessing activity of recombinant antigen receptors
|
EP3704230A1
(en)
|
2017-11-01 |
2020-09-09 |
Juno Therapeutics, Inc. |
Process for generating therapeutic compositions of engineered cells
|
WO2019090110A1
(en)
*
|
2017-11-03 |
2019-05-09 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-ror1 immunotherapy
|
CN111556893A
(zh)
|
2017-11-06 |
2020-08-18 |
爱迪塔斯医药股份有限公司 |
免疫疗法t细胞中cblb的crispr-cas9编辑的方法、组合物和组分
|
US20200289565A1
(en)
|
2017-11-06 |
2020-09-17 |
Juno Therapeutics, Inc. |
Combination of a cell therapy and a gamma secretase inhibitor
|
AU2018364562A1
(en)
*
|
2017-11-09 |
2020-06-18 |
Medimmune, Llc |
Bispecific fusion polypeptides and methods of use thereof
|
CN111683962A
(zh)
*
|
2017-11-10 |
2020-09-18 |
美国政府(由卫生和人类服务部的部长所代表) |
靶向肿瘤抗原的嵌合抗原受体
|
JP2021502094A
(ja)
|
2017-11-10 |
2021-01-28 |
ジュノー セラピューティクス インコーポレイテッド |
閉鎖系極低温容器
|
US11649294B2
(en)
|
2017-11-14 |
2023-05-16 |
GC Cell Corporation |
Anti-HER2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same
|
US20210179733A1
(en)
*
|
2017-11-14 |
2021-06-17 |
Green Cross Lab Cell Corporation |
Anti-her2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same
|
US20220267403A1
(en)
|
2017-12-01 |
2022-08-25 |
Fred Hutchinson Cancer Research Center |
Binding proteins specific for 5t4 and uses thereof
|
MA51210A
(fr)
|
2017-12-01 |
2020-10-07 |
Juno Therapeutics Inc |
Procédés de dosage et de modulation de cellules génétiquement modifiées
|
WO2019113556A1
(en)
|
2017-12-08 |
2019-06-13 |
Juno Therapeutics, Inc. |
Serum-free media formulation for culturing cells and methods of use thereof
|
MA51114A
(fr)
|
2017-12-08 |
2020-10-14 |
Juno Therapeutics Inc |
Procédé de production d'une compositions de lymphocytes t modifiés
|
US20210128616A1
(en)
|
2017-12-08 |
2021-05-06 |
Juno Therapeutics, Inc. |
Phenotypic markers for cell therapy and related methods
|
MA51184A
(fr)
|
2017-12-15 |
2020-10-21 |
Juno Therapeutics Inc |
Molécules de liaison à l'anti-cct5 et procédés d'utilisation associés
|
WO2019126358A1
(en)
*
|
2017-12-22 |
2019-06-27 |
Cell Design Labs, Inc. |
Single- and multi-chain chimeric antigen receptors
|
CN109971837A
(zh)
*
|
2017-12-28 |
2019-07-05 |
上海细胞治疗研究院 |
一种外源抗体基因拷贝数的检测方法和试剂盒
|
US11919937B2
(en)
|
2018-01-09 |
2024-03-05 |
Board Of Regents, The University Of Texas System |
T cell receptors for immunotherapy
|
WO2019140278A1
(en)
|
2018-01-11 |
2019-07-18 |
Fred Hutchinson Cancer Research Center |
Immunotherapy targeting core binding factor antigens
|
CN112292138A
(zh)
|
2018-01-22 |
2021-01-29 |
西雅图儿童医院(Dba西雅图儿童研究所) |
Car t细胞的使用方法
|
US20210069246A1
(en)
|
2018-01-31 |
2021-03-11 |
Celgene Corporation |
Combination therapy using adoptive cell therapy and checkpoint inhibitor
|
JP2021511802A
(ja)
|
2018-01-31 |
2021-05-13 |
ジュノー セラピューティクス インコーポレイテッド |
複製可能ウイルスの存在または非存在を評価するための方法および試薬
|
EP3749695A4
(en)
*
|
2018-02-06 |
2021-12-29 |
Seattle Children's Hospital (DBA Seattle Children's Research Institute) |
Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors
|
MX2020008403A
(es)
|
2018-02-12 |
2020-09-25 |
Hutchinson Fred Cancer Res |
Receptores de celulas t especificos de ciclina a1 y usos de los mismos.
|
EP3759130A1
(en)
|
2018-02-26 |
2021-01-06 |
Fred Hutchinson Cancer Research Center |
Compositions and methods for cellular immunotherapy
|
WO2019170845A1
(en)
|
2018-03-09 |
2019-09-12 |
Ospedale San Raffaele S.R.L. |
Il-1 antagonist and toxicity induced by cell therapy
|
US10751399B2
(en)
*
|
2018-03-20 |
2020-08-25 |
Cho Pharma Usa, Inc. |
Chimeric antigen receptors that bind to SSEA4 and uses thereof
|
WO2019191334A1
(en)
|
2018-03-28 |
2019-10-03 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
EP3774864A1
(en)
|
2018-03-28 |
2021-02-17 |
Cero Therapeutics, Inc. |
Chimeric engulfment receptors and uses thereof for neurodegenerative diseases
|
JP7444781B2
(ja)
|
2018-03-28 |
2024-03-06 |
セロ・セラピューティクス・インコーポレイテッド |
細胞免疫療法組成物およびその使用
|
CA3093969A1
(en)
|
2018-03-28 |
2019-10-03 |
Cero Therapeutics, Inc. |
Expression vectors for chimeric engulfment receptors, genetically modified host cells, and uses thereof
|
SG11202009446TA
(en)
|
2018-04-05 |
2020-10-29 |
Juno Therapeutics Inc |
T cells expressing a recombinant receptor, related polynucleotides and methods
|
SG11202009284TA
(en)
|
2018-04-05 |
2020-10-29 |
Juno Therapeutics Inc |
T cell receptors and engineered cells expressing same
|
CA3094468A1
(en)
|
2018-04-05 |
2019-10-10 |
Juno Therapeutics, Inc. |
Methods of producing cells expressing a recombinant receptor and related compositions
|
WO2019200347A1
(en)
*
|
2018-04-13 |
2019-10-17 |
Fred Hutchinson Cancer Research Center |
Methods for adoptive cell therapy targeting ror1
|
WO2019210153A1
(en)
|
2018-04-27 |
2019-10-31 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
EP3788369A1
(en)
|
2018-05-01 |
2021-03-10 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
US20210121466A1
(en)
|
2018-05-03 |
2021-04-29 |
Juno Therapeutics, Inc. |
Combination therapy of a chimeric antigen receptor (car) t cell therapy and a kinase inhibitor
|
EP3801769A1
(en)
|
2018-05-25 |
2021-04-14 |
Novartis AG |
Combination therapy with chimeric antigen receptor (car) therapies
|
CN108441505B
(zh)
*
|
2018-05-28 |
2023-07-07 |
上海恒润达生生物科技股份有限公司 |
一种靶向ror1的嵌合抗原受体及其用途
|
WO2019232479A2
(en)
|
2018-06-01 |
2019-12-05 |
Fred Hutchinson Cancer Research Center |
Biomarkers, uses thereof for selecting immunotherapy intervention, and immunotherapy methods
|
EP3802825A1
(en)
|
2018-06-08 |
2021-04-14 |
Intellia Therapeutics, Inc. |
Compositions and methods for immunooncology
|
CA3100724A1
(en)
|
2018-06-13 |
2019-12-19 |
Novartis Ag |
B-cell maturation antigen protein (bcma) chimeric antigen receptors and uses thereof
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
WO2020018964A1
(en)
|
2018-07-20 |
2020-01-23 |
Fred Hutchinson Cancer Research Center |
Compositions and methods for controlled expression of antigen-specific receptors
|
EP3833759A1
(en)
|
2018-08-09 |
2021-06-16 |
Juno Therapeutics, Inc. |
Methods for assessing integrated nucleic acids
|
JP2021533746A
(ja)
|
2018-08-09 |
2021-12-09 |
ジュノー セラピューティクス インコーポレイテッド |
操作された細胞およびその組成物を生成するための方法
|
KR20210043622A
(ko)
*
|
2018-08-10 |
2021-04-21 |
주식회사 유틸렉스 |
암항원 특이적 세포독성 t세포
|
JP7394840B2
(ja)
|
2018-08-31 |
2023-12-08 |
アンヴェクティ エスアー |
複数のhla-gアイソフォームに対するキメラ抗原レセプター
|
JP2021534784A
(ja)
*
|
2018-08-31 |
2021-12-16 |
シアトル チルドレンズ ホスピタル (ディービーエイ シアトル チルドレンズ リサーチ インスティテュート) |
B7h3キメラ抗原受容体を含む方法および組成物
|
MA53612A
(fr)
|
2018-09-11 |
2021-09-15 |
Juno Therapeutics Inc |
Procédés d'analyse par spectrométrie de masse de compositions cellulaires modifiées
|
WO2020056170A1
(en)
|
2018-09-12 |
2020-03-19 |
Fred Hutchinson Cancer Research Center |
Reducing cd33 expression to selectively protect therapeutic cells
|
WO2020068702A1
(en)
|
2018-09-24 |
2020-04-02 |
Fred Hutchinson Cancer Research Center |
Chimeric receptor proteins and uses thereof
|
NL2021789B1
(en)
|
2018-10-10 |
2020-05-14 |
Academisch Ziekenhuis Leiden |
Binding proteins specific for HA-1H and uses thereof
|
US20220002669A1
(en)
|
2018-10-31 |
2022-01-06 |
Juno Therapeutics Gmbh |
Methods for selection and stimulation of cells and apparatus for same
|
CN112969467A
(zh)
*
|
2018-10-31 |
2021-06-15 |
贝里坤制药股份有限公司 |
具有***开关的t细胞
|
JP2022512917A
(ja)
|
2018-11-01 |
2022-02-07 |
ジュノー セラピューティクス インコーポレイテッド |
B細胞成熟抗原に特異的なキメラ抗原受容体を使用する処置方法
|
EP3873937A2
(en)
*
|
2018-11-01 |
2021-09-08 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for g protein-coupled receptor class c group 5 member d (gprc5d)
|
EP3877054B1
(en)
|
2018-11-06 |
2023-11-01 |
Juno Therapeutics, Inc. |
Process for producing genetically engineered t cells
|
JP2022512971A
(ja)
|
2018-11-08 |
2022-02-07 |
ジュノー セラピューティクス インコーポレイテッド |
処置およびt細胞調節のための方法および併用
|
MX2021005734A
(es)
|
2018-11-16 |
2021-09-10 |
Juno Therapeutics Inc |
Metodos de dosificacion de celulas t modificadas para el tratamiento de malignidades de celulas b.
|
JP2022513076A
(ja)
|
2018-11-19 |
2022-02-07 |
ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム |
Carおよびtcr形質導入用のモジュール式ポリシストロニックベクター
|
BR112021010297A2
(pt)
|
2018-11-28 |
2021-08-24 |
Board Of Regents, The University Of Texas System |
Edição de genomas multiplexadores de células imunes para aumentar a funcionalidade e resistência ao ambiente supressivo
|
AU2019386830A1
(en)
|
2018-11-29 |
2021-06-24 |
Board Of Regents, The University Of Texas System |
Methods for ex vivo expansion of natural killer cells and use thereof
|
JP2022513689A
(ja)
|
2018-11-30 |
2022-02-09 |
ジュノー セラピューティクス インコーポレイテッド |
養子細胞療法におけるb細胞悪性腫瘍の投与および処置のための方法
|
WO2020113194A2
(en)
|
2018-11-30 |
2020-06-04 |
Juno Therapeutics, Inc. |
Methods for treatment using adoptive cell therapy
|
WO2020127513A1
(en)
|
2018-12-19 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Mucosal-associated invariant t (mait) cells expressing chimeric antigen receptors
|
BR112021011874A2
(pt)
|
2018-12-20 |
2021-09-08 |
Novartis Ag |
Regime de dosagem e combinação farmacêutica compreendendo derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona
|
EP3917570A1
(en)
|
2019-01-29 |
2021-12-08 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for receptor tyrosine kinase like orphan receptor 1 (ror1)
|
MX2021009763A
(es)
|
2019-02-15 |
2021-09-08 |
Novartis Ag |
Derivados de 3-(1-oxo-5-(piperidin-4-il)isoindolin-2-il)piperidina -2,6-diona y usos de los mismos.
|
KR20210129672A
(ko)
|
2019-02-15 |
2021-10-28 |
노파르티스 아게 |
치환된 3-(1-옥소이소인돌린-2-일)피페리딘-2,6-디온 유도체 및 이의 용도
|
GB2596461B
(en)
|
2019-02-20 |
2023-09-27 |
Fred Hutchinson Cancer Center |
Binding proteins specific for RAS neoantigens and uses thereof
|
WO2020180882A1
(en)
|
2019-03-05 |
2020-09-10 |
Nkarta, Inc. |
Cd19-directed chimeric antigen receptors and uses thereof in immunotherapy
|
WO2020223535A1
(en)
|
2019-05-01 |
2020-11-05 |
Juno Therapeutics, Inc. |
Cells expressing a recombinant receptor from a modified tgfbr2 locus, related polynucleotides and methods
|
JP2022531577A
(ja)
|
2019-05-01 |
2022-07-07 |
ジュノー セラピューティクス インコーポレイテッド |
改変されたcd247遺伝子座からキメラ受容体を発現する細胞、関連ポリヌクレオチド、および方法
|
CN114450395A
(zh)
|
2019-05-16 |
2022-05-06 |
华盛顿大学 |
Lockr介导的car t细胞募集
|
WO2020247832A1
(en)
|
2019-06-07 |
2020-12-10 |
Juno Therapeutics, Inc. |
Automated t cell culture
|
EP3983006A1
(en)
|
2019-06-12 |
2022-04-20 |
Juno Therapeutics, Inc. |
Combination therapy of a cell-mediated cytotoxic therapy and an inhibitor of a prosurvival bcl2 family protein
|
AU2020295715A1
(en)
*
|
2019-06-19 |
2022-02-17 |
Julius-Maximilians-Universität Würzburg |
Ultramodular IgG3-based spacer domain and multi-function site for implementation in chimeric antigen receptor design
|
JP2022539248A
(ja)
|
2019-07-02 |
2022-09-07 |
フレッド ハッチンソン キャンサー リサーチ センター |
組換えad35ベクター及び関連遺伝子治療改善
|
CA3145223A1
(en)
*
|
2019-07-23 |
2021-01-28 |
Wen Yang |
Composition and method for adoptive immunotherapy
|
JP2022542102A
(ja)
|
2019-07-23 |
2022-09-29 |
ムネモ・セラピューティクス |
Suv39h1欠損免疫細胞
|
WO2021035194A1
(en)
|
2019-08-22 |
2021-02-25 |
Juno Therapeutics, Inc. |
Combination therapy of a t cell therapy and an enhancer of zeste homolog 2 (ezh2) inhibitor and related methods
|
KR20220073738A
(ko)
|
2019-08-30 |
2022-06-03 |
주노 쎄러퓨티크스 인코퍼레이티드 |
세포 분류를 위한 기계 학습 방법
|
AU2020343407A1
(en)
|
2019-09-02 |
2022-03-24 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Immunotherapy targeting tumor neoantigenic peptides
|
CN114729368A
(zh)
|
2019-09-09 |
2022-07-08 |
斯克里贝治疗公司 |
用于免疫疗法的组合物和方法
|
US20220356246A1
(en)
*
|
2019-09-27 |
2022-11-10 |
Nanjing Immunophage Biotech Co.,Ltd. |
Anti-ROR1 antibodies and preparation method and uses thereof
|
WO2021067875A1
(en)
|
2019-10-03 |
2021-04-08 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
WO2021078910A1
(en)
|
2019-10-22 |
2021-04-29 |
Institut Curie |
Immunotherapy targeting tumor neoantigenic peptides
|
JP2023500318A
(ja)
|
2019-10-30 |
2023-01-05 |
ジュノ セラピューティクス ゲーエムベーハー |
細胞選択および/または細胞刺激デバイスならびに使用方法
|
JP2022554348A
(ja)
|
2019-11-05 |
2022-12-28 |
ジュノー セラピューティクス インコーポレイテッド |
治療用t細胞組成物の属性を決定する方法
|
JP2022554353A
(ja)
|
2019-11-07 |
2022-12-28 |
ジュノー セラピューティクス インコーポレイテッド |
T細胞療法と(s)-3-[4-(4-モルホリン-4-イルメチル-ベンジルオキシ)-1-オキソ-1,3-ジヒドロ-イソインドール-2-イル]-ピペリジン-2,6-ジオンとの併用
|
JP2023504740A
(ja)
|
2019-12-06 |
2023-02-06 |
ジュノー セラピューティクス インコーポレイテッド |
Bcma標的結合ドメインに対する抗イディオタイプ抗体ならびに関連する組成物および方法
|
CN115398231A
(zh)
|
2019-12-06 |
2022-11-25 |
朱诺治疗学股份有限公司 |
与治疗b细胞恶性肿瘤的细胞疗法相关的毒性和反应的相关方法
|
WO2021113780A1
(en)
|
2019-12-06 |
2021-06-10 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to gprc5d-targeted binding domains and related compositions and methods
|
CA3165399A1
(en)
|
2019-12-20 |
2021-06-24 |
Novartis Ag |
Uses of anti-tgf-beta antibodies and checkpoint inhibitors for the treatment of proliferative diseases
|
BR112022014501A2
(pt)
|
2020-01-24 |
2022-09-20 |
Juno Therapeutics Inc |
Métodos para dosagem e tratamento de linfoma folicular e linfoma de zona marginal em terapia celular adotiva
|
CN115427550A
(zh)
|
2020-01-28 |
2022-12-02 |
朱诺治疗学股份有限公司 |
T细胞转导方法
|
WO2021163389A1
(en)
|
2020-02-12 |
2021-08-19 |
Juno Therapeutics, Inc. |
Bcma-directed chimeric antigen receptor t cell compositions and methods and uses thereof
|
JP2023519098A
(ja)
|
2020-02-12 |
2023-05-10 |
ジュノー セラピューティクス インコーポレイテッド |
Cd19指向性キメラ抗原受容体t細胞組成物ならびにその方法および使用
|
WO2021167908A1
(en)
|
2020-02-17 |
2021-08-26 |
Board Of Regents, The University Of Texas System |
Methods for expansion of tumor infiltrating lymphocytes and use thereof
|
WO2021173674A1
(en)
|
2020-02-26 |
2021-09-02 |
A2 Biotherapeutics, Inc. |
Polypeptides targeting mage-a3 peptide-mhc complexes and methods of use thereof
|
CN113402612A
(zh)
|
2020-03-17 |
2021-09-17 |
西比曼生物科技(香港)有限公司 |
靶向cd19和cd20的联合嵌合抗原受体及其应用
|
WO2021207689A2
(en)
|
2020-04-10 |
2021-10-14 |
Juno Therapeutics, Inc. |
Methods and uses related to cell therapy engineered with a chimeric antigen receptor targeting b-cell maturation antigen
|
AU2021263765A1
(en)
|
2020-04-28 |
2022-12-01 |
Juno Therapeutics, Inc. |
Combination of BCMA-directed T cell therapy and an immunomodulatory compound
|
EP4149968A1
(en)
*
|
2020-05-12 |
2023-03-22 |
Lyell Immunopharma, Inc. |
Chimeric antigen receptor spacers
|
US20230212243A1
(en)
|
2020-05-12 |
2023-07-06 |
Institut Curie |
Neoantigenic Epitopes Associated with SF3B1 Mutations
|
US20230181641A1
(en)
|
2020-05-13 |
2023-06-15 |
Juno Therapeutics, Inc. |
Process for producing donor-batched cells expressing a recombinant receptor
|
CN115803824A
(zh)
|
2020-05-13 |
2023-03-14 |
朱诺治疗学股份有限公司 |
鉴定与临床反应相关的特征的方法及其用途
|
US20230212256A1
(en)
|
2020-05-21 |
2023-07-06 |
Board Of Regents, The University Of Texas System |
T cell receptors with vgll1 specificity and uses thereof
|
WO2021235894A1
(en)
*
|
2020-05-22 |
2021-11-25 |
Green Cross Lab Cell Corporation |
Anti-HER2 Antibody or Antigen-binding Fragment thereof, and Chimeric Antigen Receptor Comprising Same
|
IL298473A
(en)
|
2020-06-11 |
2023-01-01 |
Novartis Ag |
zbtb32 inhibitors and uses thereof
|
BR112022026202A2
(pt)
|
2020-06-23 |
2023-01-17 |
Novartis Ag |
Regime de dosagem compreendendo derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona
|
WO2021260186A1
(en)
|
2020-06-26 |
2021-12-30 |
Juno Therapeutics Gmbh |
Engineered t cells conditionally expressing a recombinant receptor, related polynucleotides and methods
|
US20230310606A1
(en)
|
2020-07-17 |
2023-10-05 |
Simurx, Inc. |
Chimeric myd88 receptors for redirecting immunosuppressive signaling and related compositions and methods
|
AU2021316727A1
(en)
|
2020-07-30 |
2023-03-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Immune cells defective for SOCS1
|
CN116134027A
(zh)
|
2020-08-03 |
2023-05-16 |
诺华股份有限公司 |
杂芳基取代的3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物及其用途
|
US20230324408A1
(en)
|
2020-08-05 |
2023-10-12 |
Juno Therapeutics, Inc. |
Anti-idiotypic antibodies to ror1-targeted binding domains and related compositions and methods
|
WO2022036265A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Chimeric tim receptors and uses thereof
|
WO2022036285A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Compositions and methods for treating cancer with chimeric tim receptors in combination with inhibitors of poly (adp-ribose) polymerase
|
WO2022036287A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Anti-cd72 chimeric receptors and uses thereof
|
CN112111014A
(zh)
*
|
2020-09-22 |
2020-12-22 |
廖文强 |
一种抗氧化嵌合型抗原受体和免疫细胞
|
JP2023542528A
(ja)
|
2020-09-24 |
2023-10-10 |
フレッド ハッチンソン キャンサー センター |
Sox2抗原を標的とする免疫療法
|
WO2022066973A1
(en)
|
2020-09-24 |
2022-03-31 |
Fred Hutchinson Cancer Research Center |
Immunotherapy targeting pbk or oip5 antigens
|
NL2026614B1
(en)
|
2020-10-02 |
2022-06-03 |
Academisch Ziekenhuis Leiden |
T cell receptors directed against bob1 and uses thereof
|
WO2022076353A1
(en)
|
2020-10-06 |
2022-04-14 |
Fred Hutchinson Cancer Research Center |
Compositions and methods for treating mage-a1-expressing disease
|
CN116802203A
(zh)
|
2020-11-04 |
2023-09-22 |
朱诺治疗学股份有限公司 |
从经修饰的恒定cd3免疫球蛋白超家族链基因座表达嵌合受体的细胞、相关多核苷酸和方法
|
IL302412A
(en)
|
2020-11-06 |
2023-06-01 |
Novartis Ag |
Anti-CD19 and B-cell targeting agent combination therapy for the treatment of B-cell malignancies
|
US20230051406A1
(en)
|
2020-11-13 |
2023-02-16 |
Catamaran Bio, Inc. |
Genetically modified natural killer cells and methods of use thereof
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
CN116981685A
(zh)
*
|
2020-12-03 |
2023-10-31 |
世纪治疗股份有限公司 |
基因工程化细胞及其用途
|
CN112481284B
(zh)
*
|
2020-12-07 |
2023-07-25 |
深圳瑞吉生物科技有限公司 |
一种编码CAR基因的mRNA、组合mRNA、构建方法、CAR-T细胞和应用
|
CA3204368A1
(en)
*
|
2020-12-08 |
2022-06-16 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Anti-egfr chimeric antigen receptors
|
CA3201767A1
(en)
|
2020-12-14 |
2022-06-23 |
Thomas M. Schmitt |
Compositions and methods for cellular immunotherapy
|
WO2022133030A1
(en)
|
2020-12-16 |
2022-06-23 |
Juno Therapeutics, Inc. |
Combination therapy of a cell therapy and a bcl2 inhibitor
|
US20240053250A1
(en)
|
2020-12-16 |
2024-02-15 |
Juno Therapeutics, Inc. |
Threshold gating for flow cytometry methods
|
WO2022150731A1
(en)
|
2021-01-11 |
2022-07-14 |
Sana Biotechnology, Inc. |
Use of cd8-targeted viral vectors
|
KR20230148837A
(ko)
*
|
2021-02-25 |
2023-10-25 |
라이엘 이뮤노파마, 인크. |
Ror1 표적화 키메라 항원 수용체
|
BR112023017213A2
(pt)
|
2021-02-26 |
2023-11-21 |
Kelonia Therapeutics Inc |
Vetores lentivirais direcionados a linfócitos
|
EP4301755A1
(en)
|
2021-03-03 |
2024-01-10 |
Juno Therapeutics, Inc. |
Combination of a t cell therapy and a dgk inhibitor
|
AU2022232196A1
(en)
|
2021-03-11 |
2023-09-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Transmembrane neoantigenic peptides
|
IL305810A
(en)
|
2021-03-11 |
2023-11-01 |
Mnemo Therapeutics |
Neoantigenic peptides from cancer
|
IL305809A
(en)
|
2021-03-11 |
2023-11-01 |
Mnemo Therapeutics |
Cancer neoantigenic peptides and their use
|
KR20230158573A
(ko)
|
2021-03-22 |
2023-11-20 |
주노 쎄러퓨티크스 인코퍼레이티드 |
바이러스 벡터 입자의 효력을 평가하는 방법
|
KR20230159851A
(ko)
|
2021-03-22 |
2023-11-22 |
주노 쎄러퓨티크스 인코퍼레이티드 |
치료 세포 조성물의 효력을 결정하는 방법
|
WO2022212384A1
(en)
|
2021-03-29 |
2022-10-06 |
Juno Therapeutics, Inc. |
Combination of a car t cell therapy and an immunomodulatory compound for treatment of lymphoma
|
KR20240005700A
(ko)
|
2021-03-29 |
2024-01-12 |
주노 쎄러퓨티크스 인코퍼레이티드 |
체크포인트 억제제 요법 및 car t 세포 요법의 조합을 사용한 투여 및 치료 방법
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
CN117529333A
(zh)
|
2021-04-16 |
2024-02-06 |
细胞基因公司 |
对先前进行过干细胞移植的患者的t细胞疗法
|
JP2024514163A
(ja)
|
2021-04-16 |
2024-03-28 |
セルジーン コーポレーション |
Bcma指向性t細胞療法を用いた併用療法
|
CN113735978B
(zh)
*
|
2021-04-22 |
2023-06-30 |
河北森朗生物科技有限公司 |
靶向cd19的嵌合抗原受体、制备方法及其应用
|
WO2022234009A2
(en)
|
2021-05-06 |
2022-11-10 |
Juno Therapeutics Gmbh |
Methods for stimulating and transducing t cells
|
TW202317602A
(zh)
|
2021-07-15 |
2023-05-01 |
福瑞德哈金森腫瘤中心 |
嵌合多肽
|
WO2023010097A1
(en)
|
2021-07-28 |
2023-02-02 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
TW202321457A
(zh)
|
2021-08-04 |
2023-06-01 |
美商薩那生物科技公司 |
靶向cd4之病毒載體之用途
|
WO2023014922A1
(en)
|
2021-08-04 |
2023-02-09 |
The Regents Of The University Of Colorado, A Body Corporate |
Lat activating chimeric antigen receptor t cells and methods of use thereof
|
AU2022330106A1
(en)
|
2021-08-16 |
2024-03-21 |
Hemogenyx Pharmaceuticals Llc |
Anti-flt3 antibodies, cars, car t cells and methods of use
|
WO2023081715A1
(en)
|
2021-11-03 |
2023-05-11 |
Viracta Therapeutics, Inc. |
Combination of car t-cell therapy with btk inhibitors and methods of use thereof
|
WO2023081735A1
(en)
|
2021-11-03 |
2023-05-11 |
Celgene Corporation |
Chimeric antigen receptors specific for b-cell maturation antigen for use in treating myeloma
|
WO2023105000A1
(en)
|
2021-12-09 |
2023-06-15 |
Zygosity Limited |
Vector
|
TW202342498A
(zh)
|
2021-12-17 |
2023-11-01 |
美商薩那生物科技公司 |
經修飾副黏液病毒科融合醣蛋白
|
WO2023115041A1
(en)
|
2021-12-17 |
2023-06-22 |
Sana Biotechnology, Inc. |
Modified paramyxoviridae attachment glycoproteins
|
WO2023126458A1
(en)
|
2021-12-28 |
2023-07-06 |
Mnemo Therapeutics |
Immune cells with inactivated suv39h1 and modified tcr
|
WO2023139269A1
(en)
|
2022-01-21 |
2023-07-27 |
Mnemo Therapeutics |
Modulation of suv39h1 expression by rnas
|
WO2023147515A1
(en)
|
2022-01-28 |
2023-08-03 |
Juno Therapeutics, Inc. |
Methods of manufacturing cellular compositions
|
WO2023150518A1
(en)
|
2022-02-01 |
2023-08-10 |
Sana Biotechnology, Inc. |
Cd3-targeted lentiviral vectors and uses thereof
|
WO2023150801A2
(en)
*
|
2022-02-07 |
2023-08-10 |
Seattle Children's Hospital D/B/A Seattle Children's Research Institute |
Recombinant proteins that stimulate an immune response in the presence of naturally inhibitory ligand binding
|
NL2030990B1
(en)
|
2022-02-17 |
2023-09-01 |
Academisch Ziekenhuis Leiden |
T cell receptors directed against jchain and uses thereof
|
WO2023156587A1
(en)
|
2022-02-18 |
2023-08-24 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of tcr-deficient car-tregs in combination with anti-tcr complex monoclonal antibodies for inducing durable tolerance
|
WO2023164440A1
(en)
|
2022-02-22 |
2023-08-31 |
Juno Therapeutics, Inc. |
Proteinase 3 (pr3) chimeric autoantibody receptor t cells and related methods and uses
|
NL2031118B1
(en)
|
2022-03-01 |
2023-09-07 |
Academisch Ziekenhuis Leiden |
T cell receptors directed against transcription factor wt1 and uses thereof
|
WO2023178348A1
(en)
|
2022-03-18 |
2023-09-21 |
The Regents Of The University Of Colorado, A Body Corporate |
Genetically engineered t-cell co-receptors and methods of use thereof
|
WO2023180552A1
(en)
|
2022-03-24 |
2023-09-28 |
Institut Curie |
Immunotherapy targeting tumor transposable element derived neoantigenic peptides in glioblastoma
|
WO2023193015A1
(en)
|
2022-04-01 |
2023-10-05 |
Sana Biotechnology, Inc. |
Cytokine receptor agonist and viral vector combination therapies
|
WO2023196933A1
(en)
|
2022-04-06 |
2023-10-12 |
The Regents Of The University Of Colorado, A Body Corporate |
Chimeric antigen receptor t cells and methods of use thereof
|
WO2023196921A1
(en)
|
2022-04-06 |
2023-10-12 |
The Regents Of The University Of Colorado, A Body Corporate |
Granzyme expressing t cells and methods of use
|
WO2023211972A1
(en)
|
2022-04-28 |
2023-11-02 |
Medical University Of South Carolina |
Chimeric antigen receptor modified regulatory t cells for treating cancer
|
WO2023215725A1
(en)
|
2022-05-02 |
2023-11-09 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
WO2023213969A1
(en)
|
2022-05-05 |
2023-11-09 |
Juno Therapeutics Gmbh |
Viral-binding protein and related reagents, articles, and methods of use
|
WO2023220655A1
(en)
|
2022-05-11 |
2023-11-16 |
Celgene Corporation |
Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy
|
WO2023220641A2
(en)
|
2022-05-11 |
2023-11-16 |
Juno Therapeutics, Inc. |
Methods and uses related to t cell therapy and production of same
|
WO2023225569A1
(en)
|
2022-05-17 |
2023-11-23 |
Umoja Biopharma, Inc. |
Manufacturing viral particles
|
EP4279085A1
(en)
|
2022-05-20 |
2023-11-22 |
Mnemo Therapeutics |
Compositions and methods for treating a refractory or relapsed cancer or a chronic infectious disease
|
WO2023230548A1
(en)
|
2022-05-25 |
2023-11-30 |
Celgene Corporation |
Method for predicting response to a t cell therapy
|
WO2023230581A1
(en)
|
2022-05-25 |
2023-11-30 |
Celgene Corporation |
Methods of manufacturing t cell therapies
|
WO2023235819A1
(en)
*
|
2022-06-01 |
2023-12-07 |
Seattle Children's Hospital D/B/A Seattle Children's Research Institute |
Recombinant receptors binding b cell activation factor receptor and uses thereof
|
WO2023237663A1
(en)
|
2022-06-09 |
2023-12-14 |
Institut National de la Santé et de la Recherche Médicale |
Use of the f359l missense irf4 variant for increasing the stability of regulatory t cells
|
NL2032130B1
(en)
|
2022-06-10 |
2023-12-18 |
Academisch Ziekenhuis Leiden |
T cell receptors directed against melanoma-associated antigen and uses thereof
|
WO2023250400A1
(en)
|
2022-06-22 |
2023-12-28 |
Juno Therapeutics, Inc. |
Treatment methods for second line therapy of cd19-targeted car t cells
|
WO2024006960A1
(en)
|
2022-06-29 |
2024-01-04 |
Juno Therapeutics, Inc. |
Lipid nanoparticles for delivery of nucleic acids
|
WO2024031091A2
(en)
|
2022-08-05 |
2024-02-08 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for gprc5d and bcma
|
WO2024044779A2
(en)
|
2022-08-26 |
2024-02-29 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for delta-like ligand 3 (dll3)
|
WO2024047110A1
(en)
|
2022-08-31 |
2024-03-07 |
Institut National de la Santé et de la Recherche Médicale |
Method to generate more efficient car-t cells
|
WO2024054944A1
(en)
|
2022-09-08 |
2024-03-14 |
Juno Therapeutics, Inc. |
Combination of a t cell therapy and continuous or intermittent dgk inhibitor dosing
|
WO2024062138A1
(en)
|
2022-09-23 |
2024-03-28 |
Mnemo Therapeutics |
Immune cells comprising a modified suv39h1 gene
|
WO2024074713A1
(en)
|
2022-10-07 |
2024-04-11 |
Institut National de la Santé et de la Recherche Médicale |
Method to generate improving car-t cells
|
WO2024081820A1
(en)
|
2022-10-13 |
2024-04-18 |
Sana Biotechnology, Inc. |
Viral particles targeting hematopoietic stem cells
|