USRE43932E1
(en)
|
1997-07-18 |
2013-01-15 |
Novartis Ag |
Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use
|
CO4940418A1
(es)
*
|
1997-07-18 |
2000-07-24 |
Novartis Ag |
Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
|
ITMI992711A1
(it)
*
|
1999-12-27 |
2001-06-27 |
Novartis Ag |
Composti organici
|
US7087608B2
(en)
|
2000-03-03 |
2006-08-08 |
Robert Charles Atkins |
Use of PDGF receptor tyrosine kinase inhibitors for the treatment of diabetic nephropathy
|
PL209733B1
(pl)
*
|
2000-10-27 |
2011-10-31 |
Novartis Ag |
Zastosowanie 4-(4-metylopiperazyno-1-ylometylo)-N-[4-metylo-3-(4-pirydyn-3-ylo)pirymidyn-2-yloamino)fenylo]benzamidu w leczeniu żołądkowo-jelitowych guzów podścieliskowych
|
ES2640787T3
(es)
|
2001-02-19 |
2017-11-06 |
Novartis Ag |
Combinación de un derivado de rapamicina y letrozol para tratar el cáncer de mama
|
CN1511036B
(zh)
*
|
2001-02-27 |
2010-05-05 |
诺瓦提斯公司 |
包含信号转导抑制剂和埃坡霉素衍生物的联合形式
|
GB0108606D0
(en)
*
|
2001-04-05 |
2001-05-23 |
Novartis Ag |
Organic compounds
|
PL392652A1
(pl)
*
|
2001-05-16 |
2010-12-06 |
Novartis Ag |
Kombinacja zawierająca N-{5-[4-(4-metylo-piperazyno-metylo)-benzoiloamido]-2-metylofenylo}-4-(3-pirydylo)-2-pirymidyno-aminę oraz środek chemoterapeutyczny, jej zastosowanie, kompozycja farmaceutyczna ją zawierająca oraz zestaw zawierający taką kombinację
|
AU2005246965B2
(en)
*
|
2001-05-16 |
2008-04-17 |
Novartis Ag |
Combination comprising N-{5-[4(4-methyl-piperazino-methyl)-bezoylamido]-2-methylphenyl}-4-(3-pyridyl)-2pyrimidine-amine and a chemotherapeutic agent
|
EP1704863A3
(en)
*
|
2001-05-16 |
2010-11-24 |
Novartis AG |
Combination comprising N-5-4-(4-Methyl-Piperazino-Methyl-)Benzoyla Mido]-2-Methylphenyl -4-(3-Pyridyl)-2Phyrimidine-amine and a chemotherapeutic agent
|
AU2002345670A1
(en)
|
2001-06-14 |
2003-01-02 |
The Regents Of The University Of California |
Mutations in the bcr-abl tyrosine kinase associated with resistance to sti-571
|
WO2003000186A2
(en)
|
2001-06-21 |
2003-01-03 |
Ariad Pharmaceuticals, Inc. |
Novel phenylamino-pyrimidines and uses thereof
|
WO2003003006A2
(en)
*
|
2001-06-29 |
2003-01-09 |
Ab Science |
New potent, selective and non toxic c-kit inhibitors
|
WO2003002108A2
(en)
|
2001-06-29 |
2003-01-09 |
Ab Science |
Use of tyrosine kinase inhibitors for treating inflammatory diseases
|
EP1401416B1
(en)
|
2001-06-29 |
2006-10-25 |
AB Science |
Use of c-kit inhibitors for treating inflammatory bowel diseases (ibd)
|
CA2452371A1
(en)
|
2001-06-29 |
2003-01-09 |
Ab Science |
Use of tyrosine kinase inhibitors for treating allergic diseases
|
CN1523991A
(zh)
|
2001-08-10 |
2004-08-25 |
��˹��ŵ�� |
单独的c-Src抑制剂或其与STI571的组合用于治疗白血病的用途
|
GB0120690D0
(en)
|
2001-08-24 |
2001-10-17 |
Novartis Ag |
Organic compounds
|
EP1427422A1
(en)
*
|
2001-09-20 |
2004-06-16 |
AB Science |
Use of tyrosine kinase inhibitors for whitening human skin and treating melanocyte dysfunction associated diseases
|
ATE434038T1
(de)
|
2001-10-05 |
2009-07-15 |
Novartis Ag |
Mutierte abl-kinase-domänen
|
US7045523B2
(en)
|
2001-10-18 |
2006-05-16 |
Novartis Ag |
Combination comprising N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine and telomerase inhibitor
|
EP1441749A4
(en)
*
|
2001-10-25 |
2010-05-19 |
Wisconsin Alumni Res Found |
STENT OR VASCULAR GRAFT COATED OR IMPREGNATED WITH TYROSINE KINASE INHIBITORS AND METHOD OF USE THEREOF
|
GB0127922D0
(en)
*
|
2001-11-21 |
2002-01-16 |
Novartis Ag |
Organic compounds
|
GB0201508D0
(en)
|
2002-01-23 |
2002-03-13 |
Novartis Ag |
Organic compounds
|
GB0201882D0
(en)
*
|
2002-01-28 |
2002-03-13 |
Novartis Ag |
Organic compounds
|
AU2007201056B2
(en)
*
|
2002-01-28 |
2010-06-10 |
Hyks-Instituutti Oy |
Treatment of rheumatoid arthritis using imatinib
|
GB0202873D0
(en)
|
2002-02-07 |
2002-03-27 |
Novartis Ag |
Organic compounds
|
WO2003070248A1
(en)
*
|
2002-02-22 |
2003-08-28 |
The Government Of The United States The Department Of Veterans Affairs |
Use of 4-(4-methylpiperazin-1-ylmethyl)-n[4-methyl-3-(4-pyridin-3-yl) pyrimidin-2-ylamino) phenyl]-benzamide for treating seminomas
|
RU2341266C2
(ru)
*
|
2002-02-28 |
2008-12-20 |
Новартис Аг |
Стенты с нанесенным покрытием, содержащим n-{5-[4-(4-метилпиперазинометил)бензоиламидо]-2-метилфенил}-4-(3-пиридил)-2-пиримидинамин
|
DK1487424T3
(da)
*
|
2002-03-15 |
2007-01-08 |
Novartis Ag |
4-(4-Methylpiperazin-1-ylmethyl)-N-(4-methyl-3-(4-pyridin-3-yl)-pyrimidin-2-yl-amino)phenyl-benzamid til behandling af Ang II-medierede sygdomme
|
GB0206215D0
(en)
|
2002-03-15 |
2002-05-01 |
Novartis Ag |
Organic compounds
|
CA2479257A1
(en)
*
|
2002-03-21 |
2003-10-02 |
Dana-Farber Cancer Institute, Inc. |
Inhibition of cell death responses induced by oxidative stress
|
WO2003086497A1
(en)
*
|
2002-04-16 |
2003-10-23 |
Issam Moussa |
Drug eluting vascular stent and method of treating hyperproliferative vascular disease
|
AU2007201830C1
(en)
*
|
2002-04-23 |
2017-09-07 |
Novartis Pharma Ag |
High drug load tablet
|
GB0209265D0
(en)
*
|
2002-04-23 |
2002-06-05 |
Novartis Ag |
Organic compounds
|
NZ560662A
(en)
|
2002-05-16 |
2009-09-25 |
Novartis Ag |
Use of EDG receptor binding agents in cancer
|
US20060052387A1
(en)
*
|
2002-06-26 |
2006-03-09 |
Marsh Clay B |
Organic compounds
|
DK1533304T3
(da)
|
2002-06-28 |
2010-03-22 |
Nippon Shinyaku Co Ltd |
Amidderivat
|
JP2005531628A
(ja)
*
|
2002-06-28 |
2005-10-20 |
ジ アドミニストレイターズ オブ ザ チューレン エデュケイショナル ファンド |
肺線維症の処置のための4−(4−メチルピペラジン−1−イルメチル)−n−[4−メチル−3−(4−ピリジン−3−イル)ピリミジン−2−イルアミノ)フェニル]−ベンズアミド
|
JP2005538756A
(ja)
*
|
2002-07-18 |
2005-12-22 |
メドトロニック・エイヴイイー・インコーポレーテッド |
再狭窄を阻害するためのタンパク質−チロシンキナーゼ阻害物質を含んでなる医療デバイス
|
EP1530474A1
(en)
*
|
2002-07-19 |
2005-05-18 |
Ludwig Institute For Cancer Research |
Enhancing the effect of radioimmunotherapy in the treatment of tumors
|
US20060116381A1
(en)
*
|
2002-07-24 |
2006-06-01 |
Fagin James A |
4-4(methylpiperazin-1-ylmethyl)-n-[4-methyl-3-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-ben-zamide for treating mutated-ret kinase associated diseases
|
EP1551408A1
(en)
*
|
2002-07-24 |
2005-07-13 |
Novartis AG |
4-(4-methylpiperazin-1-ylmethyl)-n- 4-pyridin-3-yl)pyrimidin -2-ylamino)phenyl -benzamide for treating anaplastic thyroid cancer
|
ATE360015T1
(de)
*
|
2002-07-31 |
2007-05-15 |
Critical Outcome Technologies |
Protein tyrosin kinase inhibitoren
|
JP4726486B2
(ja)
|
2002-08-02 |
2011-07-20 |
アブ サイエンス |
2−(3−アミノアリール)アミノ−4−アリール−チアゾールおよびそれらのc−kit阻害薬としての使用法
|
US8450302B2
(en)
|
2002-08-02 |
2013-05-28 |
Ab Science |
2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors
|
CA2439440A1
(en)
|
2002-09-05 |
2004-03-05 |
Emory University |
Treatment of tuberous sclerosis associated neoplasms
|
AU2003273675A1
(en)
*
|
2002-10-09 |
2004-05-04 |
Wayne R. Danter |
Protein tyrosine kinase inhibitors
|
GB0224455D0
(en)
*
|
2002-10-21 |
2002-11-27 |
Novartis Ag |
Organic compounds
|
WO2004037261A1
(en)
*
|
2002-10-25 |
2004-05-06 |
The Administrators Of The Tulane Educational Fund |
Use of n-‘5-‘4-(4-methylpiperaziomethyl)-benzoylamido!-2-methylphenyl!-4-(3-pyridyl)2-pyridine-amine for the treatment of pulmonary hypertension
|
US7094785B1
(en)
|
2002-12-18 |
2006-08-22 |
Cornell Research Foundation, Inc. |
Method of treating polycythemia vera
|
GB2398565A
(en)
*
|
2003-02-18 |
2004-08-25 |
Cipla Ltd |
Imatinib preparation and salts
|
JP2006513791A
(ja)
*
|
2003-04-04 |
2006-04-27 |
ベイコ テック リミテッド |
血管用ステント
|
WO2004099186A1
(en)
|
2003-05-06 |
2004-11-18 |
Il Yang Pharm Co., Ltd. |
N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof
|
MY150088A
(en)
|
2003-05-19 |
2013-11-29 |
Irm Llc |
Immunosuppressant compounds and compositions
|
CA2524048C
(en)
|
2003-05-19 |
2013-06-25 |
Irm Llc |
Immunosuppressant compounds and compositions
|
DE602004022540D1
(de)
*
|
2003-05-27 |
2009-09-24 |
Robert P Haegerkvist |
Verwendung von tyrosin-kinase-hemmern zur behandlung von diabetes
|
GB0312086D0
(en)
*
|
2003-05-27 |
2003-07-02 |
Novartis Ag |
Organic compounds
|
US7300938B2
(en)
|
2003-06-02 |
2007-11-27 |
Hetero Drugs Limited |
Polymorphs of imatinib mesylate
|
JP2006526652A
(ja)
*
|
2003-06-03 |
2006-11-24 |
ベス・イスラエル・ディーコニス・メディカル・センター |
血管狭窄を治療するための方法及び化合物
|
WO2005027971A1
(en)
*
|
2003-09-19 |
2005-03-31 |
Novartis Ag |
Treatment of gastrointestinal stromal tumors with imatinib and midostaurin
|
CA2542909C
(en)
|
2003-10-23 |
2012-07-10 |
Ab Science |
2-aminoaryloxazole compounds as tyrosine kinase inhibitors
|
CN101693031A
(zh)
|
2003-11-18 |
2010-04-14 |
诺瓦提斯公司 |
Kit突变形式的抑制剂
|
WO2005063720A1
(ja)
*
|
2003-12-25 |
2005-07-14 |
Nippon Shinyaku Co., Ltd. |
アミド誘導体及び医薬
|
AR047530A1
(es)
|
2004-02-04 |
2006-01-25 |
Novartis Ag |
Formas de sal de 4-(4-metilpiperazin-1-ilmetil)-n-(4-metil-3-(4-piridin-3-il)pirimidin-2-ilamino)fenil)-benzamida
|
PT1720853E
(pt)
*
|
2004-02-11 |
2016-03-04 |
Natco Pharma Ltd |
Nova forma polimórfica de mesilato de imatinib e processo para a sua preparação
|
CN1309719C
(zh)
*
|
2004-02-18 |
2007-04-11 |
陈国庆 |
苯氨基嘧啶衍生物及其用途
|
UA84462C2
(ru)
*
|
2004-04-02 |
2008-10-27 |
Институт Фармацевтични |
Полиморфные модификации кислотно-аддитивных солей иматиниба с метансульфоновой кислотой
|
KR20080083220A
(ko)
|
2004-04-07 |
2008-09-16 |
노파르티스 아게 |
Iap 억제제
|
GB0512324D0
(en)
|
2005-06-16 |
2005-07-27 |
Novartis Ag |
Organic compounds
|
AU2005269052A1
(en)
*
|
2004-07-01 |
2006-02-09 |
The Netherlands Cancer Institute |
Combination comprising a BCRP inhibitor and 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide
|
TR200701870T1
(tr)
|
2004-09-02 |
2007-05-21 |
Cipla Limited |
İmatinib mesilatın kararlı kristal formu ve bu formun hazırlanması için işlem.
|
CA2591321C
(en)
|
2004-09-09 |
2013-09-24 |
Natco Pharma Limited |
Phenylaminopyrimidine derivatives as inhibitors of bcr-abl kinase
|
US8735415B2
(en)
|
2004-09-09 |
2014-05-27 |
Natco Pharma Limited |
Acid addition salts of (3,5-Bis trifluoromethyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide
|
WO2006048890A1
(en)
*
|
2004-11-04 |
2006-05-11 |
Sun Pharmaceutical Industries Limited |
Imatinib mesylate crystal form and process for preparation thereof
|
WO2006054314A1
(en)
*
|
2004-11-17 |
2006-05-26 |
Natco Pharma Limited |
Polymorphic forms of imatinib mesylate
|
CA2592118C
(en)
|
2004-12-23 |
2015-11-17 |
Deciphera Pharmaceuticals, Llc |
Urea derivatives as enzyme modulators
|
UA95071C2
(ru)
|
2005-04-04 |
2011-07-11 |
Аб Сьянс |
Замещенные производные оксазола и их применение как ингибиторов тирозинкиназы
|
BRPI0609296A2
(pt)
|
2005-05-02 |
2010-03-23 |
Novartis Ag |
uso de derivados de pirimidilaminobenzamida para o tratamento de mastocitose sistÊmica
|
GB0510390D0
(en)
|
2005-05-20 |
2005-06-29 |
Novartis Ag |
Organic compounds
|
NZ563446A
(en)
|
2005-06-03 |
2011-02-25 |
Novartis Ag |
Combination of pyrimidylaminobenzamide compounds and imatinib for treating or preventing proliferative diseases
|
GT200600316A
(es)
*
|
2005-07-20 |
2007-04-02 |
|
Sales de 4-metilo-n-(3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo)-3-(4-piridina-3-ilo-pirimidina-2-iloamino)- benzamida.
|
KR100674813B1
(ko)
|
2005-08-05 |
2007-01-29 |
일양약품주식회사 |
N-페닐-2-피리미딘-아민 유도체 및 그의 제조방법
|
ES2334933T3
(es)
|
2005-08-15 |
2010-03-17 |
Siegfried Generics International Ag |
Comprimido recubierto o granulado que contiene una piridilpirimidina.
|
UY29766A1
(es)
*
|
2005-08-26 |
2007-03-30 |
Novartis Ag |
Formas cristalinas delta y épsilon de mesilato de imatinib
|
BRPI0618808A2
(pt)
|
2005-11-21 |
2011-09-13 |
Novartis Ag |
uso de um inibidor de mtor
|
CA2824307C
(en)
|
2005-11-25 |
2016-03-29 |
Novartis Ag |
F, g, h, i and k crystal forms of imatinib mesylate
|
GB0605120D0
(en)
|
2006-03-14 |
2006-04-26 |
Novartis Ag |
Organic Compounds
|
WO2007124252A2
(en)
|
2006-04-05 |
2007-11-01 |
Novartis Ag |
Combinations of therapeutic agents for treating cancer
|
CA2644143C
(en)
|
2006-04-05 |
2013-10-01 |
Novartis Ag |
Combinations comprising bcr-abl/c-kit/pdgf-r tk inhibitors for treating cancer
|
US7977348B2
(en)
|
2006-04-27 |
2011-07-12 |
Sicor Inc. |
Polymorphic forms of imatinib mesylate and processes for preparation of novel crystalline forms as well as amorphous and form α
|
EP2829538A1
(en)
|
2006-04-27 |
2015-01-28 |
Sicor, Inc. |
Polymorphic form of imatinib mesylate and process for its preparation
|
US8067421B2
(en)
|
2006-04-27 |
2011-11-29 |
Sicor Inc. |
Polymorphic forms of imatinib mesylate and processes for preparation of novel crystalline forms as well as amorphous and form α
|
US20060223816A1
(en)
*
|
2006-05-08 |
2006-10-05 |
Chemagis Ltd. |
Imatinib mesylate alpha form and production process therefor
|
CN101443002B
(zh)
|
2006-05-09 |
2012-03-21 |
诺瓦提斯公司 |
包含铁螯合剂和抗肿瘤药的组合及其用途
|
US20060223817A1
(en)
*
|
2006-05-15 |
2006-10-05 |
Chemagis Ltd. |
Crystalline imatinib base and production process therefor
|
WO2008004945A1
(en)
*
|
2006-07-04 |
2008-01-10 |
Astrazeneca Ab |
Novel crystalline forms i and ii
|
WO2008004944A1
(en)
*
|
2006-07-04 |
2008-01-10 |
Astrazeneca Ab |
Novel crystalline form ii
|
US8246966B2
(en)
|
2006-08-07 |
2012-08-21 |
University Of Georgia Research Foundation, Inc. |
Trypanosome microsome system and uses thereof
|
CN101951889A
(zh)
*
|
2006-09-01 |
2011-01-19 |
特瓦制药工业有限公司 |
伊马替尼组合物
|
DK2068938T3
(da)
|
2006-09-22 |
2011-04-04 |
Novartis Ag |
Optimering af behandlingen af Philadelphia-positiv leukæmi med ABL-tyrosinkinaseinhibitor imatinib
|
JP2010504933A
(ja)
|
2006-09-29 |
2010-02-18 |
ノバルティス アーゲー |
Pi3k脂質キナーゼ阻害剤としてのピラゾロピリミジン
|
JP2009514988A
(ja)
*
|
2006-10-26 |
2009-04-09 |
シコール インコーポレイティド |
イマチニブ塩基及びイマチニブメシレート、及びそれらの調製方法
|
EP2009008A1
(en)
|
2006-10-26 |
2008-12-31 |
Sicor, Inc. |
Imatinib base, and imatinib mesylate and processes for preparation thereof
|
WO2008070350A2
(en)
|
2006-10-27 |
2008-06-12 |
The Board Of Regents Of The University Of Texas System |
Methods and compositions related to wrapping of dehydrons
|
AU2007316558A1
(en)
*
|
2006-11-09 |
2008-05-15 |
Abbott Gmbh & Co. Kg |
Pharmaceutical dosage form for oral administration of tyrosine kinase inhibitor
|
EP1920767A1
(en)
*
|
2006-11-09 |
2008-05-14 |
Abbott GmbH & Co. KG |
Melt-processed imatinib dosage form
|
CA2669531A1
(en)
|
2006-11-22 |
2008-06-05 |
University Of Georgia Research Foundation, Inc. |
Tyrosine kinase inhibitors as anti-kinetolastid and anti-apicomplexan agents
|
US8034815B2
(en)
|
2007-01-11 |
2011-10-11 |
Critical Outcome Technologies, Inc. |
Compounds and method for treatment of cancer
|
EP2125895B1
(en)
|
2007-02-02 |
2015-04-08 |
Vegenics Pty Ltd |
Vegf receptor antagonists for treating organ transplant alloimmunity and arteriosclerosis
|
KR100799821B1
(ko)
*
|
2007-02-05 |
2008-01-31 |
동화약품공업주식회사 |
신규한 이마티닙 캠실레이트 및 그의 제조방법
|
US8153792B2
(en)
*
|
2007-02-13 |
2012-04-10 |
Ab Science |
Process for the synthesis of 2-aminothiazole compounds as kinase inhibitors
|
CN101626758A
(zh)
|
2007-02-15 |
2010-01-13 |
诺瓦提斯公司 |
用于治疗癌症的lbh589和其他治疗剂的组合
|
CN101265274B
(zh)
*
|
2007-02-16 |
2013-09-04 |
中国医学科学院药物研究所 |
嘧啶噻唑胺衍生物、及其制法和药物组合物与用途
|
JP2010521477A
(ja)
*
|
2007-03-12 |
2010-06-24 |
ドクター レディズ ラボラトリーズ リミテッド |
イマチニブメシレート
|
US20080234286A1
(en)
*
|
2007-03-20 |
2008-09-25 |
Chemagis Ltd. |
Stable amorphous imatinib mesylate and production process therefor
|
US7550591B2
(en)
|
2007-05-02 |
2009-06-23 |
Chemagis Ltd. |
Imatinib production process
|
WO2008136010A1
(en)
*
|
2007-05-07 |
2008-11-13 |
Natco Pharma Limited |
A process for the preparation of highly pure imatinib base
|
WO2008150481A2
(en)
*
|
2007-05-29 |
2008-12-11 |
Sicor Inc. |
Processes for the preparation of crystalline form beta of imatinib mesylate
|
PT2305263E
(pt)
|
2007-06-07 |
2012-10-22 |
Novartis Ag |
Formas amorfas estabilizadas de mesilato de imatinib
|
BRPI0817946A2
(pt)
*
|
2007-09-25 |
2015-05-05 |
Teva Pharma |
Composições de imatinibe estável
|
US20090082361A1
(en)
*
|
2007-09-26 |
2009-03-26 |
Protia, Llc |
Deuterium-enriched imatinib
|
US8501740B2
(en)
*
|
2007-10-09 |
2013-08-06 |
Board Of Regents, The University Of Texas System |
Methods of treatment of opioid tolerance, physical dependence, pain and addiction with inhibitors of certain growth factor receptors
|
CA2710039C
(en)
|
2007-12-26 |
2018-07-03 |
Critical Outcome Technologies, Inc. |
Semicarbazones, thiosemicarbazones and related compounds and methods for treatment of cancer
|
CA2719457C
(en)
|
2008-03-24 |
2017-05-02 |
Novartis Ag |
Arylsulfonamide-based matrix metalloprotease inhibitors
|
AU2009228778B2
(en)
|
2008-03-26 |
2012-04-19 |
Novartis Ag |
Hydroxamate-based inhibitors of deacetylases B
|
CN101584696A
(zh)
*
|
2008-05-21 |
2009-11-25 |
上海艾力斯医药科技有限公司 |
包含喹唑啉衍生物的组合物及制备方法、用途
|
ES2645689T3
(es)
|
2008-05-21 |
2017-12-07 |
Ariad Pharmaceuticals, Inc. |
Derivados de fósforo como inhibidores de quinasas
|
US9273077B2
(en)
|
2008-05-21 |
2016-03-01 |
Ariad Pharmaceuticals, Inc. |
Phosphorus derivatives as kinase inhibitors
|
TWI508728B
(zh)
|
2008-06-27 |
2015-11-21 |
Univ Indiana Res & Tech Corp |
抑制及/或治療神經纖維瘤及相關腫瘤的材料和方法
|
DE102008031037A1
(de)
|
2008-06-30 |
2009-12-31 |
Dömling, Alexander, Priv.-Doz. Dr. |
Gleevec zur Anwedung in der Organtransplantation
|
WO2010006438A1
(en)
|
2008-07-17 |
2010-01-21 |
Critical Outcome Technologies Inc. |
Thiosemicarbazone inhibitor compounds and cancer treatment methods
|
US20100221221A1
(en)
*
|
2008-08-12 |
2010-09-02 |
Concert Pharmaceuticals Inc. |
N-phenyl-2-pyrimidineamine derivatives
|
US20200155558A1
(en)
|
2018-11-20 |
2020-05-21 |
Boehringer Ingelheim International Gmbh |
Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
|
US20110223241A1
(en)
|
2008-10-16 |
2011-09-15 |
Celator Pharmaceuticals, Inc. |
Combination methods and compositions
|
EP2186514B1
(en)
*
|
2008-11-14 |
2016-06-29 |
Kinki University |
Treatment of Malignant Peripheral Nerve Sheath Tumors
|
EP2370078A1
(en)
|
2008-12-01 |
2011-10-05 |
Novartis AG |
Method of optimizing the treatment of philadelphia-positive leukemia with imatinib mesylate
|
WO2010080409A1
(en)
|
2008-12-18 |
2010-07-15 |
Novartis Ag |
Hemifumarate salt of 1- [4- [1- ( 4 -cyclohexyl-3 -trifluoromethyl-benzyloxyimino ) -ethyl] -2 -ethyl-benzyl] -a zetidine-3-carboxylic acid
|
US8173634B2
(en)
|
2008-12-18 |
2012-05-08 |
Novartis Ag |
Polymorphic form of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic
|
US8486930B2
(en)
|
2008-12-18 |
2013-07-16 |
Novartis Ag |
Salts
|
WO2010083617A1
(en)
|
2009-01-21 |
2010-07-29 |
Oncalis Ag |
Pyrazolopyrimidines as protein kinase inhibitors
|
TW201031406A
(en)
|
2009-01-29 |
2010-09-01 |
Novartis Ag |
Substituted benzimidazoles for the treatment of astrocytomas
|
UA103918C2
(en)
|
2009-03-02 |
2013-12-10 |
Айерем Элелси |
N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as wnt signaling modulators
|
WO2010120386A1
(en)
|
2009-04-17 |
2010-10-21 |
Nektar Therapeutics |
Oligomer-protein tyrosine kinase inhibitor conjugates
|
BRPI1013336B1
(pt)
|
2009-04-28 |
2020-02-04 |
Daiichi Sankyo Co Ltd |
cristais solvatos de acetona, métodos para produção dos referidos cristais e método para produção de olmesartana medoxomila
|
US20100330130A1
(en)
|
2009-05-22 |
2010-12-30 |
Actavis Group Ptc Ehf |
Substantially pure imatinib or a pharmaceutically acceptable salt thereof
|
TW201102068A
(en)
*
|
2009-06-02 |
2011-01-16 |
Novartis Ag |
Treatment of ophthalmologic disorders mediated by alpha-carbonic anhydrase isoforms
|
CA2765983C
(en)
|
2009-06-26 |
2017-11-14 |
Novartis Ag |
1,3-disubstituted imidazolidin-2-one derivatives as inhibitors of cyp 17
|
US8389526B2
(en)
|
2009-08-07 |
2013-03-05 |
Novartis Ag |
3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
|
MX2012001838A
(es)
|
2009-08-12 |
2012-02-29 |
Novartis Ag |
Compuestos de hidrazona heterociclico y sus usos para tratar cancer e inflamacion.
|
CA2771532C
(en)
|
2009-08-17 |
2021-03-23 |
Intellikine, Inc. |
Heterocyclic compounds and uses thereof
|
BR112012008061A2
(pt)
|
2009-08-20 |
2016-03-01 |
Novartis Ag |
compostos de oxima heterocíclica
|
WO2011023677A1
(en)
|
2009-08-26 |
2011-03-03 |
Novartis Ag |
Tetra-substituted heteroaryl compounds and their use as mdm2 and/or mdm4 modulators
|
CZ2009570A3
(cs)
|
2009-08-26 |
2011-03-09 |
Zentiva, K. S. |
Príprava, stabilizace a využití polymorfu imatinib mesylátu pro vývoj lékových forem
|
EP2475668A1
(en)
|
2009-09-10 |
2012-07-18 |
Novartis AG |
Ether derivatives of bicyclic heteroaryls
|
WO2011039782A1
(en)
*
|
2009-09-29 |
2011-04-07 |
Ind-Swift Laboratories Limited |
Processes for preparing imatinib and pharmaceutically acceptable salts thereof
|
PL389357A1
(pl)
|
2009-10-22 |
2011-04-26 |
Tomasz Koźluk |
Sole imatinibu z pochodnymi kwasów winowych i sposób ich wytwarzania
|
JP5466767B2
(ja)
|
2009-11-04 |
2014-04-09 |
ノバルティス アーゲー |
Mek阻害剤として有用なヘテロ環式スルホンアミド誘導体
|
JP6220126B2
(ja)
|
2009-11-23 |
2017-10-25 |
セルリアン・ファーマ・インコーポレイテッド |
治療的送達のためのシクロデキストリンに基づく重合体
|
JP2013512215A
(ja)
|
2009-11-25 |
2013-04-11 |
ノバルティス アーゲー |
二環式ヘテロアリールのベンゼン縮合6員酸素含有ヘテロ環誘導体
|
EP2509964B1
(en)
|
2009-12-08 |
2014-04-30 |
Novartis AG |
Heterocyclic sulfonamide derivatives
|
US8440693B2
(en)
|
2009-12-22 |
2013-05-14 |
Novartis Ag |
Substituted isoquinolinones and quinazolinones
|
CU24130B1
(es)
|
2009-12-22 |
2015-09-29 |
Novartis Ag |
Isoquinolinonas y quinazolinonas sustituidas
|
WO2011090940A1
(en)
|
2010-01-19 |
2011-07-28 |
Cerulean Pharma Inc. |
Cyclodextrin-based polymers for therapeutic delivery
|
WO2011095835A1
(en)
|
2010-02-02 |
2011-08-11 |
Actavis Group Ptc Ehf |
Highly pure imatinib or a pharmaceutically acceptable salt thereof
|
WO2011099039A1
(en)
|
2010-02-15 |
2011-08-18 |
Reliance Life Sciences Pvt. Ltd. |
Process for the preparation of alpha form of imatinib mesylate
|
PL390611A1
(pl)
|
2010-03-04 |
2011-09-12 |
Tomasz Koźluk |
Sposób otrzymywania polimorficznej formy alfa i nowa forma polimorficzna mesylanu imatinibu
|
WO2011114337A1
(en)
|
2010-03-15 |
2011-09-22 |
Natco Pharma Limited |
Process for the preparation of highly pure crystalline imatinib base
|
US20110237686A1
(en)
|
2010-03-26 |
2011-09-29 |
Cerulean Pharma Inc |
Formulations and methods of use
|
CA2999435A1
(en)
|
2010-04-01 |
2011-10-06 |
Critical Outcome Technologies Inc. |
Compounds and method for treatment of hiv
|
WO2011130918A1
(zh)
|
2010-04-23 |
2011-10-27 |
上海百灵医药科技有限公司 |
一种伊马替尼的合成方法
|
EP2382976A1
(en)
|
2010-04-30 |
2011-11-02 |
Hiroshima University |
Use of pdgf-r inhibitors for the treatment of lymph node metastasis of gastric cancer
|
WO2011158255A1
(en)
*
|
2010-06-16 |
2011-12-22 |
Aptuit Laurus Private Limited |
Process for preparation of stable imatintb mesylate alpha form
|
EP2583967B1
(en)
*
|
2010-06-16 |
2014-10-01 |
Takeda Pharmaceutical Company Limited |
Crystal of amide compound
|
WO2011157787A1
(en)
|
2010-06-17 |
2011-12-22 |
Novartis Ag |
Biphenyl substituted 1,3-dihydro-benzoimidazol-2-ylideneamine derivatives
|
WO2011157793A1
(en)
|
2010-06-17 |
2011-12-22 |
Novartis Ag |
Piperidinyl substituted 1,3-dihydro-benzoimidazol-2-ylideneamine derivatives
|
WO2011157450A1
(en)
|
2010-06-18 |
2011-12-22 |
Krka, D. D., Novo Mesto |
New polymorphic form of imatinib base and preparation of salts thereof
|
UA112517C2
(uk)
|
2010-07-06 |
2016-09-26 |
Новартіс Аг |
Тетрагідропіридопіримідинові похідні
|
RU2013110058A
(ru)
|
2010-08-11 |
2014-09-20 |
Синтон Б.В. |
Фармацевтический гранулят, содержащий иматиниба мезилат
|
TR201007005A2
(tr)
|
2010-08-23 |
2011-09-21 |
Mustafa Nevzat İlaç Sanayi̇i̇ A.Ş. |
İmatinib baz üretim yöntemi
|
RU2456280C2
(ru)
*
|
2010-08-27 |
2012-07-20 |
Общество с ограниченной ответственностью "Химфармресурс" |
Кристаллическая n-модификация 4-[(4-метил-1-пиперазинил)метил]-n-[4-метил-3-[[4-(3-пиридинил)-2-пиримидинил]-амино]-фенил] бензамида метансульфоната, способ ее получения и фармацевтическая композиция на ее основе
|
WO2012027716A1
(en)
|
2010-08-27 |
2012-03-01 |
Collabrx, Inc. |
Method to treat melanoma in braf inhibitor-resistant subjects
|
US8946260B2
(en)
|
2010-09-16 |
2015-02-03 |
Novartis Ag |
17α-hydroxylase/C17,20-lyase inhibitors
|
US9034883B2
(en)
|
2010-11-15 |
2015-05-19 |
Boehringer Ingelheim International Gmbh |
Vasoprotective and cardioprotective antidiabetic therapy
|
CN102477031B
(zh)
|
2010-11-30 |
2015-07-15 |
浙江九洲药业股份有限公司 |
一种甲磺酸伊马替尼α晶型的制备方法
|
TR201010618A2
(tr)
|
2010-12-20 |
2012-07-23 |
Bi̇lgi̇ç Mahmut |
İmatinib içeren bir oral dozaj formu ve bu oral dozaj formunun üretimi
|
CN103270026A
(zh)
|
2010-12-21 |
2013-08-28 |
诺瓦提斯公司 |
作为vps34抑制剂的联-杂芳基化合物
|
WO2012090221A1
(en)
|
2010-12-29 |
2012-07-05 |
Cadila Healthcare Limited |
Novel salts of imatinib
|
WO2012107500A1
(en)
|
2011-02-10 |
2012-08-16 |
Novartis Ag |
[1, 2, 4] triazolo [4, 3 -b] pyridazine compounds as inhibitors of the c-met tyrosine kinase
|
CN102649785B
(zh)
*
|
2011-02-23 |
2015-08-19 |
江苏先声药物研究有限公司 |
一种伊玛替尼甲烷磺酸盐β晶型的制备方法
|
CN102146073A
(zh)
*
|
2011-02-23 |
2011-08-10 |
江苏先声药物研究有限公司 |
一种伊玛替尼甲烷磺酸盐α晶型新的制备方法
|
JP5808826B2
(ja)
|
2011-02-23 |
2015-11-10 |
インテリカイン, エルエルシー |
複素環化合物およびその使用
|
SG10201601711SA
(en)
|
2011-03-04 |
2016-04-28 |
Newgen Therapeutics Inc |
Alkyne Substituted Quinazoline Compound And Methods Of Use
|
US20130338152A1
(en)
|
2011-03-08 |
2013-12-19 |
Irm Llc |
Fluorophenyl bicyclic heteroaryl compounds
|
PL394169A1
(pl)
|
2011-03-09 |
2012-09-10 |
Adamed Spółka Z Ograniczoną Odpowiedzialnością |
Kompozycja farmaceutyczna metanosulfonianu imatinibu do napełniania jednostkowych postaci dawkowania oraz sposób jej wytwarzania
|
EP2691385A4
(en)
|
2011-03-31 |
2014-08-13 |
Ind Swift Lab Ltd |
IMPROVED METHOD FOR THE PRODUCTION OF IMATINIB AND ITS MESYLATE SALT
|
BR112013027395A2
(pt)
|
2011-04-28 |
2017-01-17 |
Novartis Ag |
inibidores de 17alfa-hidroxilase/c17,20-liase
|
EA201391626A1
(ru)
|
2011-05-04 |
2014-03-31 |
Ариад Фармасьютикалз, Инк. |
Соединения для ингибирования клеточной пролиферации в egfr-стимулированных типах рака
|
WO2012155339A1
(zh)
|
2011-05-17 |
2012-11-22 |
江苏康缘药业股份有限公司 |
4-苯胺-6-丁烯酰胺-7-烷醚喹唑啉衍生物及其制备方法和用途
|
WO2012166899A2
(en)
|
2011-06-03 |
2012-12-06 |
Eisai R&D Management Co., Ltd. |
Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds
|
BR112013031201A2
(pt)
|
2011-06-09 |
2017-01-31 |
Novartis Ag |
derivados de sulfonamida heterocíclicos, composição farmacêutica os compreendendo, uso, processo para a fabricação de (r)-n-(4,5-difluoro-6-((2-fluoro-4-iodofenil)amino)benzofuran-7-il)-1-(2,3-di-idroxipropil)ciclopropano-5 1-sulfonamida e kit
|
US8859535B2
(en)
|
2011-06-20 |
2014-10-14 |
Novartis Ag |
Hydroxy substituted isoquinolinone derivatives
|
WO2012175487A1
(en)
|
2011-06-20 |
2012-12-27 |
Novartis Ag |
Cyclohexyl isoquinolinone compounds
|
US9750700B2
(en)
|
2011-06-22 |
2017-09-05 |
Natco Pharma Limited |
Imatinib mesylate oral pharmaceutical composition and process for preparation thereof
|
EP2723740A1
(en)
|
2011-06-27 |
2014-04-30 |
Novartis AG |
Solid forms and salts of tetrahydro-pyrido-pyrimidine derivatives
|
ITMI20111309A1
(it)
|
2011-07-14 |
2013-01-15 |
Italiana Sint Spa |
Procedimento di preparazione di imatinib mesilato
|
CN102321070B
(zh)
*
|
2011-07-27 |
2013-05-22 |
江苏先声药物研究有限公司 |
反溶剂重结晶法制备伊玛替尼甲烷磺酸盐α晶型
|
CA2848809A1
(en)
|
2011-09-15 |
2013-03-21 |
Novartis Ag |
6-substituted 3-(quinolin-6-ylthio)-[1,2,4]triazolo[4,3-a]pyradines as c-met tyrosine kinase
|
AU2012328979B2
(en)
|
2011-10-28 |
2016-04-21 |
Novartis Ag |
Method of treating gastrointestinal stromal tumors
|
WO2013063003A1
(en)
|
2011-10-28 |
2013-05-02 |
Novartis Ag |
Method of treating gastrointestinal stromal tumors
|
EP2776035B1
(en)
|
2011-11-01 |
2016-08-10 |
Modgene, Llc |
Compositions and methods for reduction of amyloid-beta load
|
CN104080787B
(zh)
|
2011-11-29 |
2016-09-14 |
诺华股份有限公司 |
吡唑并吡咯烷化合物
|
US9408885B2
(en)
|
2011-12-01 |
2016-08-09 |
Vib Vzw |
Combinations of therapeutic agents for treating melanoma
|
EP2604596A1
(en)
|
2011-12-16 |
2013-06-19 |
Deva Holding Anonim Sirketi |
Polymorphs of imatinib
|
EP2794594A1
(en)
|
2011-12-22 |
2014-10-29 |
Novartis AG |
Quinoline derivatives
|
JP5903499B2
(ja)
|
2011-12-22 |
2016-04-13 |
ノバルティス アーゲー |
ジヒドロ−ベンゾ−オキサジンおよびジヒドロ−ピリド−オキサジン誘導体
|
MX2014007729A
(es)
|
2011-12-23 |
2015-01-12 |
Novartis Ag |
Compuestos para inhibir la interaccion de bcl2 con los componentes de enlace.
|
WO2013096055A1
(en)
|
2011-12-23 |
2013-06-27 |
Novartis Ag |
Compounds for inhibiting the interaction of bcl2 with binding partners
|
AU2012355623A1
(en)
|
2011-12-23 |
2014-07-17 |
Novartis Ag |
Compounds for inhibiting the interaction of BCL2 with binding partners
|
US20130178520A1
(en)
|
2011-12-23 |
2013-07-11 |
Duke University |
Methods of treatment using arylcyclopropylamine compounds
|
CA2859873A1
(en)
|
2011-12-23 |
2013-06-27 |
Novartis Ag |
Compounds for inhibiting the interaction of bcl2 with binding partners
|
BR112014015339A2
(pt)
|
2011-12-23 |
2017-06-13 |
Novartis Ag |
compostos para inibição da interação de bcl2 com parceiros de ligação
|
PL226174B1
(pl)
|
2011-12-30 |
2017-06-30 |
Inst Farm |
Polaczenie analogu witaminy D z imatinibem do stosowania w leczeniu skojarzonym niedrobnokomorkowego raka pluc
|
UY34591A
(es)
|
2012-01-26 |
2013-09-02 |
Novartis Ag |
Compuestos de imidazopirrolidinona
|
AU2013223749A1
(en)
|
2012-02-21 |
2014-09-11 |
Sun Pharmaceutical Industries Limited |
Stable dosage forms of imatinib mesylate
|
CN102617549A
(zh)
*
|
2012-03-02 |
2012-08-01 |
瑞阳制药有限公司 |
甲磺酸伊马替尼β晶型的制备方法
|
WO2013136141A1
(en)
|
2012-03-13 |
2013-09-19 |
Fresenius Kabi Oncology Ltd. |
An improved process for the preparation of alpha form of imatinib mesylate
|
GB201204810D0
(en)
|
2012-03-20 |
2012-05-02 |
Pharos Pharmaceutical Oriented Services Ltd |
Pharmaceutical compositions
|
AU2013243097A1
(en)
|
2012-04-03 |
2014-10-09 |
Novartis Ag |
Combination products with tyrosine kinase inhibitors and their use
|
CN102617552A
(zh)
*
|
2012-04-06 |
2012-08-01 |
江南大学 |
一种制备α晶型甲磺酸伊马替尼的结晶方法
|
CN102633775B
(zh)
*
|
2012-04-06 |
2013-07-17 |
江南大学 |
一种甲磺酸伊马替尼α晶型的制备方法
|
JP2013216644A
(ja)
*
|
2012-04-11 |
2013-10-24 |
Takada Seiyaku Kk |
イマチニブメシル酸塩経口投与製剤
|
AU2013204563B2
(en)
|
2012-05-05 |
2016-05-19 |
Takeda Pharmaceutical Company Limited |
Compounds for inhibiting cell proliferation in EGFR-driven cancers
|
JP6171003B2
(ja)
|
2012-05-24 |
2017-07-26 |
ノバルティス アーゲー |
ピロロピロリジノン化合物
|
CN104582732A
(zh)
|
2012-06-15 |
2015-04-29 |
布里格姆及妇女医院股份有限公司 |
治疗癌症的组合物及其制造方法
|
WO2013189910A1
(en)
|
2012-06-22 |
2013-12-27 |
Basf Se |
Multicomponent crystals comprising imatinib mesilate and selected co-crystal formers
|
KR101242955B1
(ko)
*
|
2012-06-25 |
2013-03-12 |
제일약품주식회사 |
이마티닙 메실레이트 결정형 α의 제조 방법
|
MX2015000457A
(es)
|
2012-07-11 |
2015-04-08 |
Novartis Ag |
Metodo de tratamiento de tumores del estroma gastrointestinal.
|
WO2014016848A2
(en)
|
2012-07-24 |
2014-01-30 |
Laurus Labs Private Limited |
Solid forms of tyrosine kinase inhibitors, process for the preparation and their pharmaceutical composition thereof
|
CN104736144B
(zh)
|
2012-07-27 |
2019-02-01 |
艾祖米科技有限公司 |
外排抑制剂组合物和使用此组合物治疗的方法
|
CN103570677B
(zh)
*
|
2012-08-02 |
2017-03-01 |
广东东阳光药业有限公司 |
一种α晶型甲磺酸伊马替尼的制备方法
|
WO2014025395A1
(en)
|
2012-08-06 |
2014-02-13 |
Duke University |
Compounds and methods for targeting hsp90
|
WO2014041551A1
(en)
|
2012-09-14 |
2014-03-20 |
Natco Pharma Limited |
Formulation comprising imatinib as oral solution
|
US20150238488A1
(en)
|
2012-09-28 |
2015-08-27 |
Hangzhou Bensheng Pharmaceutical Co., Ltd. |
Drug composition for treating tumors and application thereof
|
US9439903B2
(en)
|
2012-10-25 |
2016-09-13 |
Cadila Healthcare Limited |
Process for the preparation of amorphous imatinib mesylate
|
CN110787285A
(zh)
|
2012-11-05 |
2020-02-14 |
达纳-法伯癌症研究所股份有限公司 |
Xbp1、cd138和cs1肽、包括所述肽的药物组合物及使用所述肽和组合物的方法
|
TW201422625A
(zh)
|
2012-11-26 |
2014-06-16 |
Novartis Ag |
二氫-吡啶并-□衍生物之固體形式
|
EP2749269A1
(en)
|
2012-12-31 |
2014-07-02 |
Deva Holding Anonim Sirketi |
Process for the preparation of adsorbates of imatinib
|
EP2749557A1
(en)
|
2012-12-31 |
2014-07-02 |
Deva Holding Anonim Sirketi |
Process for preparation of alpha polymorph of imatinib mesylate from IPA and THF solvate forms of imatinib mesylate
|
EP2749271A1
(en)
|
2012-12-31 |
2014-07-02 |
Deva Holding Anonim Sirketi |
Optimized manufacturing method and pharmaceutical formulation of imatinib
|
EP2948453B1
(en)
|
2013-01-22 |
2017-08-02 |
Novartis AG |
Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the p53/mdm2 interaction
|
EP2948451B1
(en)
|
2013-01-22 |
2017-07-12 |
Novartis AG |
Substituted purinone compounds
|
WO2014128612A1
(en)
|
2013-02-20 |
2014-08-28 |
Novartis Ag |
Quinazolin-4-one derivatives
|
ES2760023T3
(es)
|
2013-02-20 |
2020-05-12 |
Univ Pennsylvania |
Tratamiento del cáncer utilizando receptor de antígeno quimérico anti-EGFRvIII humanizado
|
GB201304699D0
(en)
|
2013-03-15 |
2013-05-01 |
Remedica Ltd |
Pharmaceutical compositions
|
JP2016512835A
(ja)
|
2013-03-15 |
2016-05-09 |
インテリカイン, エルエルシー |
キナーゼ阻害剤の組み合わせ及びそれらの使用
|
WO2014155268A2
(en)
|
2013-03-25 |
2014-10-02 |
Novartis Ag |
Fgf-r tyrosine kinase activity inhibitors - use in diseases associated with lack of or reduced snf5 activity
|
US9611283B1
(en)
|
2013-04-10 |
2017-04-04 |
Ariad Pharmaceuticals, Inc. |
Methods for inhibiting cell proliferation in ALK-driven cancers
|
EP2803353B1
(en)
|
2013-05-14 |
2018-05-23 |
Hetero Research Foundation |
Compositions of Imatinib
|
US20150018376A1
(en)
|
2013-05-17 |
2015-01-15 |
Novartis Ag |
Pyrimidin-4-yl)oxy)-1h-indole-1-carboxamide derivatives and use thereof
|
UY35675A
(es)
|
2013-07-24 |
2015-02-27 |
Novartis Ag |
Derivados sustituidos de quinazolin-4-ona
|
EP3782604A1
(en)
|
2013-07-31 |
2021-02-24 |
Windward Pharma, Inc. |
Aerosol tyrosine kinase inhibitor compounds and uses thereof
|
WO2015022663A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
WO2015022664A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
US9227969B2
(en)
|
2013-08-14 |
2016-01-05 |
Novartis Ag |
Compounds and compositions as inhibitors of MEK
|
EP3046563B1
(en)
|
2013-09-22 |
2019-05-29 |
Calitor Sciences, LLC |
Substituted aminopyrimidine compounds as pi3-kinase inhibitors
|
ES2748213T3
(es)
|
2013-10-17 |
2020-03-13 |
Sartar Therapeutics Ltd |
Composiciones que comprenden inhibidores de la fosfodiesterasa para su uso en el tratamiento de un tumor sólido en un paciente humano
|
US9636340B2
(en)
|
2013-11-12 |
2017-05-02 |
Ayyappan K. Rajasekaran |
Kinase inhibitors
|
TW201605450A
(zh)
|
2013-12-03 |
2016-02-16 |
諾華公司 |
Mdm2抑制劑與BRAF抑制劑之組合及其用途
|
WO2015110949A1
(en)
|
2014-01-22 |
2015-07-30 |
Novartis Ag |
Imatinib as cholesterol decreasing agent
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
CN103800671B
(zh)
*
|
2014-02-11 |
2016-02-10 |
王思成 |
一种治疗阿弗他溃疡的中药制剂
|
BR122024001145A2
(pt)
|
2014-03-14 |
2024-02-27 |
Novartis Ag |
Molécula de anticorpo isolada capaz de se ligar a lag-3, seu método de produção, composição farmacêutica, ácidos nucleicos, vetor de expressão, método para detecção de lag-3 em uma amostra biológica, e uso das referidas molécula de anticorpo e composição
|
WO2015148714A1
(en)
|
2014-03-25 |
2015-10-01 |
Duke University |
Heat shock protein 70 (hsp-70) receptor ligands
|
WO2015145388A2
(en)
|
2014-03-27 |
2015-10-01 |
Novartis Ag |
Methods of treating colorectal cancers harboring upstream wnt pathway mutations
|
CA2943979A1
(en)
|
2014-03-28 |
2015-10-01 |
Calitor Sciences, Llc |
Substituted heteroaryl compounds and methods of use
|
MX2016012893A
(es)
|
2014-04-03 |
2017-05-12 |
Invictus Oncology Pvt Ltd |
Sustancias terapéuticas combinadas supramoleculares.
|
EP2927223B1
(en)
|
2014-04-04 |
2016-06-29 |
F.I.S.- Fabbrica Italiana Sintetici S.p.A. |
Process for preparing imatinib and salts thereof, free of genotoxic impurity f
|
CN104974133B
(zh)
*
|
2014-04-09 |
2018-04-27 |
石药集团中奇制药技术(石家庄)有限公司 |
一种甲磺酸伊马替尼晶型及其制备方法
|
CN104055745A
(zh)
*
|
2014-06-11 |
2014-09-24 |
连云港杰瑞药业有限公司 |
一种甲磺酸伊马替尼片的制备方法
|
WO2016011658A1
(en)
|
2014-07-25 |
2016-01-28 |
Novartis Ag |
Combination therapy
|
EP3174869B1
(en)
|
2014-07-31 |
2020-08-19 |
Novartis AG |
Combination therapy of a met inhibitor and an egfr inhibitor
|
MX2017001980A
(es)
|
2014-08-28 |
2017-05-04 |
Eisai R&D Man Co Ltd |
Derivado de quinolina muy puro y metodo para su produccion.
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
CR20170143A
(es)
|
2014-10-14 |
2017-06-19 |
Dana Farber Cancer Inst Inc |
Moléculas de anticuerpo que se unen a pd-l1 y usos de las mismas
|
SG11201702980QA
(en)
|
2014-10-21 |
2017-05-30 |
Ariad Pharma Inc |
Crystalline forms of 5-chloro-n4-[-2-(dimethylphosphoryl) phenyl]-n2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl) piperidin-1-yl] pyrimidine-2,4-diamine
|
EP3233918A1
(en)
|
2014-12-19 |
2017-10-25 |
Novartis AG |
Combination therapies
|
KR20170122734A
(ko)
|
2015-02-25 |
2017-11-06 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
퀴놀린 유도체의 고미 억제 방법
|
KR20240064733A
(ko)
|
2015-03-04 |
2024-05-13 |
머크 샤프 앤드 돔 코포레이션 |
암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합
|
MY190404A
(en)
|
2015-03-10 |
2022-04-21 |
Aduro Biotech Inc |
Compositions and methods for activating "stimulator of interferon gene"-dependent signalling
|
CN104817536A
(zh)
*
|
2015-04-14 |
2015-08-05 |
江苏豪森药业股份有限公司 |
适合药用的甲磺酸伊马替尼非针状α晶型及其制备方法
|
WO2016204193A1
(ja)
|
2015-06-16 |
2016-12-22 |
株式会社PRISM Pharma |
抗がん剤
|
EP3878465A1
(en)
|
2015-07-29 |
2021-09-15 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
EP3317301B1
(en)
|
2015-07-29 |
2021-04-07 |
Novartis AG |
Combination therapies comprising antibody molecules to lag-3
|
WO2017044434A1
(en)
|
2015-09-11 |
2017-03-16 |
Sunshine Lake Pharma Co., Ltd. |
Substituted heteroaryl compounds and methods of use
|
EA201891093A1
(ru)
|
2015-11-03 |
2018-10-31 |
Янссен Байотек, Инк. |
Антитела, специфически связывающие pd-1, и их применение
|
WO2017078647A1
(en)
|
2015-11-05 |
2017-05-11 |
Koçak Farma Ilaç Ve Kimya Sanayi Anonim Şirketi |
Pharmaceutical compositions of imatinib
|
CN105503825B
(zh)
*
|
2015-12-16 |
2019-01-11 |
齐鲁天和惠世制药有限公司 |
一种甲磺酸伊马替尼β晶型的制备方法
|
EP3389712B1
(en)
|
2015-12-17 |
2024-04-10 |
Novartis AG |
Antibody molecules to pd-1 and uses thereof
|
CA3009610C
(en)
|
2015-12-24 |
2024-02-13 |
Takeda Pharmaceutical Company Limited |
Cocrystal of (s)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-1h-1,2,4-triazol-5(4h)-one, production method thereof and pharmaceutical composition containing said cocrystal
|
EP3407874B1
(en)
|
2016-01-25 |
2024-05-22 |
KRKA, d.d., Novo mesto |
Fast dispersible pharmaceutical composition comprising tyrosine-kinase inhibitor
|
DK3240538T3
(da)
|
2016-03-25 |
2021-12-06 |
Ab Science |
Anvendelse af masitinib til behandling af en underpopulation af patienter med amyotrofisk lateralsklerose
|
WO2017184956A1
(en)
|
2016-04-22 |
2017-10-26 |
Duke University |
Compounds and methods for targeting hsp90
|
EP3257499A1
(en)
|
2016-06-17 |
2017-12-20 |
Vipharm S.A. |
Process for preparation of imatinib methanesulfonate capsules
|
WO2018009466A1
(en)
|
2016-07-05 |
2018-01-11 |
Aduro Biotech, Inc. |
Locked nucleic acid cyclic dinucleotide compounds and uses thereof
|
WO2018039203A1
(en)
|
2016-08-23 |
2018-03-01 |
Oncopep, Inc. |
Peptide vaccines and durvalumab for treating multiple myeloma
|
WO2018039205A1
(en)
|
2016-08-23 |
2018-03-01 |
Oncopep, Inc. |
Peptide vaccines and durvalumab for treating breast cancer
|
MX2019003489A
(es)
|
2016-09-27 |
2020-01-23 |
Cero Therapeutics Inc |
Moleculas del receptor de envolvimiento quimerico.
|
US10207998B2
(en)
|
2016-09-29 |
2019-02-19 |
Duke University |
Substituted benzimidazole and substituted benzothiazole inhibitors of transforming growth factor-β kinase and methods of use thereof
|
US10927083B2
(en)
|
2016-09-29 |
2021-02-23 |
Duke University |
Substituted benzimidazoles as inhibitors of transforming growth factor-β kinase
|
TWI674094B
(zh)
|
2016-10-17 |
2019-10-11 |
日商德爾塔菲製藥股份有限公司 |
治療或緩解慢性骨髓性白血病用之醫藥組合物
|
US10777331B2
(en)
|
2016-11-11 |
2020-09-15 |
Curium Us Llc |
Processes for generating germanium-68 with reduced volatiles
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
EP3642240A1
(en)
|
2017-06-22 |
2020-04-29 |
Novartis AG |
Antibody molecules to cd73 and uses thereof
|
WO2019067328A1
(en)
|
2017-09-26 |
2019-04-04 |
Cero Therapeutics, Inc. |
CHIMERIC ENGINEERING RECEPTOR MOLECULES AND METHODS OF USE
|
WO2019083960A1
(en)
|
2017-10-24 |
2019-05-02 |
Oncopep, Inc. |
PEPTIDE VACCINES AND HDAC INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA
|
WO2019083962A1
(en)
|
2017-10-24 |
2019-05-02 |
Oncopep, Inc. |
PEPTIDE AND PEMBROLIZUMAB VACCINES FOR THE TREATMENT OF BREAST CANCER
|
US10683297B2
(en)
|
2017-11-19 |
2020-06-16 |
Calitor Sciences, Llc |
Substituted heteroaryl compounds and methods of use
|
AU2017444054B2
(en)
|
2017-12-21 |
2021-10-07 |
Hefei Institutes Of Physical Science, Chinese Academy Of Sciences |
Class of pyrimidine derivative kinase inhibitors
|
US10751339B2
(en)
|
2018-01-20 |
2020-08-25 |
Sunshine Lake Pharma Co., Ltd. |
Substituted aminopyrimidine compounds and methods of use
|
WO2019191334A1
(en)
|
2018-03-28 |
2019-10-03 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
US20210023135A1
(en)
|
2018-03-28 |
2021-01-28 |
Cero Therapeutics, Inc. |
Cellular immunotherapy compositions and uses thereof
|
EP3774869A1
(en)
|
2018-03-28 |
2021-02-17 |
Cero Therapeutics, Inc. |
Expression vectors for chimeric engulfment receptors, genetically modified host cells, and uses thereof
|
UY38247A
(es)
|
2018-05-30 |
2019-12-31 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
EP3826988A4
(en)
|
2018-07-24 |
2023-03-22 |
Hygia Pharmaceuticals, LLC |
COMPOUNDS, DERIVATIVES AND ANALOGS AGAINST CANCER
|
AU2019407426A1
(en)
|
2018-12-21 |
2021-07-22 |
Daiichi Sankyo Company, Limited |
Combination of antibody-drug conjugate and kinase inhibitor
|
US20220348651A1
(en)
|
2019-09-18 |
2022-11-03 |
Novartis Ag |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
WO2021067875A1
(en)
|
2019-10-03 |
2021-04-08 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
US20220395553A1
(en)
|
2019-11-14 |
2022-12-15 |
Cohbar, Inc. |
Cxcr4 antagonist peptides
|
WO2021185844A1
(en)
|
2020-03-16 |
2021-09-23 |
Pvac Medical Technologies Ltd |
Use of substance and pharmaceutical composition thereof, and medical treatments or uses thereof
|
WO2021233534A1
(en)
|
2020-05-20 |
2021-11-25 |
Pvac Medical Technologies Ltd |
Use of substance and pharmaceutical composition thereof, and medical treatments or uses thereof
|
WO2022029220A1
(en)
|
2020-08-05 |
2022-02-10 |
Ellipses Pharma Ltd |
Treatment of cancer using a cyclodextrin-containing polymer-topoisomerase inhibitor conjugate and a parp inhibitor
|
WO2022036285A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Compositions and methods for treating cancer with chimeric tim receptors in combination with inhibitors of poly (adp-ribose) polymerase
|
WO2022036287A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Anti-cd72 chimeric receptors and uses thereof
|
WO2022036265A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Chimeric tim receptors and uses thereof
|
TW202237638A
(zh)
|
2020-12-09 |
2022-10-01 |
日商武田藥品工業股份有限公司 |
烏苷酸環化酶c(gcc)抗原結合劑之組成物及其使用方法
|
BR112023017213A2
(pt)
|
2021-02-26 |
2023-11-21 |
Kelonia Therapeutics Inc |
Vetores lentivirais direcionados a linfócitos
|
WO2023010097A1
(en)
|
2021-07-28 |
2023-02-02 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
CN114957206B
(zh)
*
|
2022-04-11 |
2024-02-27 |
中国药科大学 |
伊马替尼共晶及其制备方法
|
WO2024030441A1
(en)
|
2022-08-02 |
2024-02-08 |
National University Corporation Hokkaido University |
Methods of improving cellular therapy with organelle complexes
|