JO2660B1
(en)
|
2006-01-20 |
2012-06-17 |
نوفارتيس ايه جي |
Pi-3 inhibitors and methods of use
|
TW200808739A
(en)
|
2006-04-06 |
2008-02-16 |
Novartis Vaccines & Diagnostic |
Quinazolines for PDK1 inhibition
|
CA2660758A1
(en)
|
2006-08-24 |
2008-02-27 |
Astrazeneca Ab |
Morpholino pyrimidine derivatives useful in the treatment of proliferative disorders
|
US7888352B2
(en)
|
2006-12-07 |
2011-02-15 |
Piramed Limited |
Phosphoinositide 3-kinase inhibitor compounds and methods of use
|
CA2675558A1
(en)
*
|
2007-02-06 |
2008-08-14 |
Novartis Ag |
Pi 3-kinase inhibitors and methods of their use
|
EP2142536B1
(de)
|
2007-04-20 |
2015-10-21 |
Probiodrug AG |
Aminopyrimidinderivate als glutaminylcyclaseinhibitoren
|
EP2155689B1
(de)
|
2007-05-31 |
2015-07-08 |
Boehringer Ingelheim International GmbH |
Ccr2-rezeptorantagonisten und anwendungen davon
|
EA018708B1
(ru)
|
2007-07-09 |
2013-10-30 |
Астразенека Аб |
ПРОИЗВОДНЫЕ МОРФОЛИНОПИРИМИДИНА, ИСПОЛЬЗУЕМЫЕ ПРИ ЗАБОЛЕВАНИЯХ, СВЯЗАННЫХ С mTOR КИНАЗОЙ И/ИЛИ PI3K
|
WO2009017838A2
(en)
*
|
2007-08-01 |
2009-02-05 |
Exelixis, Inc. |
Combinations of jak-2 inhibitors and other agents
|
US20100311736A1
(en)
*
|
2007-10-22 |
2010-12-09 |
Glaxosmithkline Llc |
Pyridosulfonamide derivatives as p13 kinase inhibitors
|
WO2009066084A1
(en)
*
|
2007-11-21 |
2009-05-28 |
F. Hoffmann-La Roche Ag |
2 -morpholinopyrimidines and their use as pi3 kinase inhibitors
|
WO2009093981A1
(en)
*
|
2008-01-23 |
2009-07-30 |
S Bio Pte Ltd |
Triazine compounds as kinase inhibitors
|
AU2009221164B2
(en)
*
|
2008-03-05 |
2012-07-26 |
Novartis Ag |
Use of pyrimidine derivatives for the treatment of EGFR dependent diseases or diseases that have acquired resistance to agents that target EGFR family members
|
AU2012203914C1
(en)
*
|
2008-03-26 |
2013-11-28 |
Novartis Ag |
5imidazoquinolines and pyrimidine derivatives as potent modulators of VEGF-driven angiogenic processes
|
BRPI0909082A2
(pt)
*
|
2008-03-26 |
2019-02-26 |
Novartis Ag |
imidazoquinolinas e derivados de pirimidina como moduladores potentes de processos angiogênicos acionados por vegf
|
WO2009120094A2
(en)
*
|
2008-03-27 |
2009-10-01 |
Auckland Uniservices Limited |
Substituted pyrimidines and triazines and their use in cancer therapy
|
US9273077B2
(en)
|
2008-05-21 |
2016-03-01 |
Ariad Pharmaceuticals, Inc. |
Phosphorus derivatives as kinase inhibitors
|
CA2723961C
(en)
|
2008-05-21 |
2017-03-21 |
Ariad Pharmaceuticals, Inc. |
Phosphorous derivatives as kinase inhibitors
|
EP2310391A1
(de)
*
|
2008-06-27 |
2011-04-20 |
S*BIO Pte Ltd |
Pyrazinsubstituierte purine
|
MX336723B
(es)
*
|
2008-07-11 |
2016-01-28 |
Novartis Ag |
Combinacion de (a) un inhibidor de fosfoinositido 3-cinasa y (b) un modulador de la ruta de ras/raf/mek.
|
PE20110196A1
(es)
*
|
2008-07-29 |
2011-04-03 |
Boehringer Ingelheim Int |
5-alquinil-pirimidinas
|
US20100068204A1
(en)
*
|
2008-09-12 |
2010-03-18 |
Wyeth |
4-aryloxyquinolin-2(1h)-ones as mtor kinase and pi3 kinase inhibitors, for use as anti-cancer agents
|
MX340304B
(es)
*
|
2008-10-01 |
2016-07-05 |
Novartis Ag * |
Antagonismo de smoothened para el tratamiento de los trastornos relacionados con la senda de hedgehog.
|
TWI378933B
(en)
|
2008-10-14 |
2012-12-11 |
Daiichi Sankyo Co Ltd |
Morpholinopurine derivatives
|
EP2349275B1
(de)
*
|
2008-10-31 |
2017-03-08 |
Novartis AG |
Kombination eines phosphoinositid-3-kinase-(pi3k)-hemmers und eines mtor-hemmers.
|
EP2356117B1
(de)
*
|
2008-11-20 |
2012-09-26 |
Genentech, Inc. |
Pyrazolopyridine als verbindungen zum inhibieren von pi3k und anwendungsverfahren
|
MA33085B1
(fr)
|
2008-12-19 |
2012-03-01 |
Boehringer Ingelheim Int |
Pyrimidine-4 carboxamides cycliques en tant qu'antagonistes du recepteur ccr2 pour le traitement d'inflammations, de l'asthme et des broncho-pneumopathies chroniques obstructives
|
EP2404918B1
(de)
|
2009-03-05 |
2016-11-30 |
Daiichi Sankyo Company, Limited |
Pyridinderivat als ppary inhibitor
|
NZ595372A
(en)
|
2009-03-27 |
2013-11-29 |
Vetdc Inc |
Pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides and their use in cancer therapy
|
AU2010234360A1
(en)
*
|
2009-04-09 |
2011-09-29 |
Oncothyreon, Incorporated |
Methods and compositions of PI-3 kinase inhibitors for treating fibrosis
|
UY32582A
(es)
|
2009-04-28 |
2010-11-30 |
Amgen Inc |
Inhibidores de fosfoinositida 3 cinasa y/u objetivo mamífero
|
CA2760179A1
(en)
*
|
2009-05-15 |
2010-11-18 |
Novartis Ag |
Combination of a phosphoinositide 3-kinase inhibitor and an antidiabetic compound
|
SG175708A1
(en)
*
|
2009-05-27 |
2011-12-29 |
Genentech Inc |
Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
|
EP2451802A1
(de)
|
2009-07-07 |
2012-05-16 |
Pathway Therapeutics, Inc. |
Pyrimidinyl- und 1,3,5-triazinyl-benzimidazole und ihre verwendung in der krebstherapie
|
US20120065166A1
(en)
*
|
2009-08-12 |
2012-03-15 |
Virginia Espina |
Bone Modulators And Methods Therewith
|
CN101993416B
(zh)
*
|
2009-08-27 |
2013-09-11 |
中国科学院上海药物研究所 |
喹啉类化合物、其制备方法、包含该化合物的药物组合物及该化合物的用途
|
CA2773848A1
(en)
*
|
2009-09-09 |
2011-03-17 |
Avila Therapeutics, Inc. |
Pi3 kinase inhibitors and uses thereof
|
EA201270568A1
(ru)
|
2009-10-16 |
2012-11-30 |
Риб-Экс Фармасьютикалз, Инк. |
Антимикробные композиции и способы их получения и применения
|
CA2777741A1
(en)
*
|
2009-10-16 |
2011-04-21 |
Rib-X Pharmaceuticals, Inc. |
Antimicrobial compounds and methods of making and using the same
|
JP5632014B2
(ja)
|
2009-12-17 |
2014-11-26 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
新規ccr2受容体アンタゴニスト及びこれらの使用
|
GB201004200D0
(en)
|
2010-03-15 |
2010-04-28 |
Univ Basel |
Spirocyclic compounds and their use as therapeutic agents and diagnostic probes
|
WO2011141474A1
(en)
|
2010-05-12 |
2011-11-17 |
Boehringer Ingelheim International Gmbh |
Novel ccr2 receptor antagonists, method for producing the same, and use thereof as medicaments
|
WO2011141477A1
(en)
|
2010-05-12 |
2011-11-17 |
Boehringer Ingelheim International Gmbh |
New ccr2 receptor antagonists, method for producing the same, and use thereof as medicaments
|
WO2011144501A1
(en)
|
2010-05-17 |
2011-11-24 |
Boehringer Ingelheim International Gmbh |
Ccr2 antagonists and uses thereof
|
US9018212B2
(en)
|
2010-05-25 |
2015-04-28 |
Boehringer Ingelheim International Gmbh |
Pyridazine carboxamides as CCR2 receptor antagonists
|
WO2011151251A1
(en)
|
2010-06-01 |
2011-12-08 |
Boehringer Ingelheim International Gmbh |
New ccr2 antagonists
|
SA111320519B1
(ar)
|
2010-06-11 |
2014-07-02 |
Astrazeneca Ab |
مركبات بيريميدينيل للاستخدام كمثبطات atr
|
EP2615081A1
(de)
|
2010-09-07 |
2013-07-17 |
Daiichi Sankyo Company, Limited |
Herstellungsverfahren für benzoesäureester
|
KR20130119928A
(ko)
*
|
2010-10-01 |
2013-11-01 |
노파르티스 아게 |
피리미딘 유도체의 제조 방법
|
CA2810900A1
(en)
*
|
2010-10-14 |
2012-04-19 |
Ariad Pharmaceuticals, Inc. |
Methods for inhibiting cell proliferation in egfr-driven cancers
|
ES2498293T3
(es)
*
|
2010-11-12 |
2014-09-24 |
Bayer Intellectual Property Gmbh |
Procedimiento para la preparación de 2,2-difluoroetilamina partiendo de prop-2-en-1-amina
|
BR112013011728A2
(pt)
|
2010-11-12 |
2016-08-16 |
Univ Texas |
terapia de combinação com dexametasona
|
JP2014500308A
(ja)
*
|
2010-12-21 |
2014-01-09 |
ノバルティス アーゲー |
Vps34阻害剤としてのビヘテロアリール化合物
|
CA2826387A1
(en)
*
|
2011-02-11 |
2012-08-16 |
Dana Farber Cancer Institute, Inc. |
Method of inhibiting hamartoma tumor cells
|
CZ305457B6
(cs)
*
|
2011-02-28 |
2015-09-30 |
Ústav organické chemie a biochemie, Akademie věd ČR v. v. i. |
Pyrimidinové sloučeniny inhibující tvorbu oxidu dusnatého a prostaglandinu E2, způsob výroby a použití
|
WO2012135160A1
(en)
|
2011-03-28 |
2012-10-04 |
Pathway Therapeutics Inc. |
(alpha- substituted aralkylamino and heteroarylalkylamino) pyrimidinyl and 1,3,5 -triazinyl benzimidazoles, pharmaceutical compositions containing them, and these compounds for use in treating proliferative diseases
|
CN103501612B
(zh)
|
2011-05-04 |
2017-03-29 |
阿里亚德医药股份有限公司 |
抑制表皮生长因子受体导致的癌症中细胞增殖的化合物
|
ES2676180T3
(es)
|
2011-07-01 |
2018-07-17 |
Novartis Ag |
Terapia de combinación que comprende un inhibidor de CDK4/6 y un inhibidor de PI3K para el uso en el tratamiento de cáncer
|
WO2013010839A1
(en)
|
2011-07-15 |
2013-01-24 |
Boehringer Ingelheim International Gmbh |
Novel and selective ccr2 antagonists
|
ES2671748T3
(es)
|
2011-07-21 |
2018-06-08 |
Tolero Pharmaceuticals, Inc. |
Inhibidores heterocíclicos de proteína quinasas
|
KR20140072028A
(ko)
|
2011-08-31 |
2014-06-12 |
노파르티스 아게 |
Pi3k- 및 mek-억제제의 상승작용적 조합물
|
CN103764130A
(zh)
*
|
2011-09-01 |
2014-04-30 |
诺华股份有限公司 |
用于治疗骨癌或者预防原发性癌细胞转移性播散入骨中的pi3k抑制剂
|
PE20141581A1
(es)
|
2011-09-27 |
2014-11-14 |
Novartis Ag |
3-pirmidin-4-il-oxazolidin-2-onas como inhibidores de la idh mutante
|
US20140235630A1
(en)
*
|
2011-09-30 |
2014-08-21 |
Beth Israel Deaconess Medical Center, Inc. |
Compositions and methods for the treatment of proliferative diseases
|
SG11201400543TA
(en)
*
|
2011-10-28 |
2014-08-28 |
Novartis Ag |
Method of treating gastrointestinal stromal tumors
|
KR20140091695A
(ko)
|
2011-11-15 |
2014-07-22 |
노파르티스 아게 |
포스포이노시티드 3-키나제 억제제와 야누스 키나제 2-신호 전달자 및 전사 활성화제 5 경로의 조절제의 조합물
|
UY34632A
(es)
*
|
2012-02-24 |
2013-05-31 |
Novartis Ag |
Compuestos de oxazolidin- 2- ona y usos de los mismos
|
SG10201704095UA
(en)
|
2012-04-24 |
2017-06-29 |
Vertex Pharma |
Dna-pk inhibitors
|
WO2013169401A1
(en)
|
2012-05-05 |
2013-11-14 |
Ariad Pharmaceuticals, Inc. |
Compounds for inhibiting cell proliferation in egfr-driven cancers
|
JP6381523B2
(ja)
*
|
2012-05-16 |
2018-08-29 |
ノバルティス アーゲー |
Pi−3キナーゼ阻害剤の投与レジメン
|
KR20160027219A
(ko)
|
2012-05-23 |
2016-03-09 |
에프. 호프만-라 로슈 아게 |
내배엽 및 간세포를 수득하고 사용하는 조성물 및 방법
|
CN104349771A
(zh)
|
2012-06-06 |
2015-02-11 |
诺华股份有限公司 |
用于***疾病的17α-羟化酶(C17,20-裂解酶)抑制剂和特定PI-3K抑制剂的组合
|
WO2013192367A1
(en)
|
2012-06-22 |
2013-12-27 |
Novartis Ag |
Neuroendocrine tumor treatment
|
WO2014006115A1
(en)
|
2012-07-06 |
2014-01-09 |
Novartis Ag |
Combination of a phosphoinositide 3-kinase inhibitor and an inhibitor of the il-8/cxcr interaction
|
CN104582707B
(zh)
*
|
2012-07-23 |
2017-09-26 |
斯法尔制药私人有限公司 |
三嗪化合物
|
CN105050623B
(zh)
*
|
2012-08-16 |
2018-06-12 |
诺华股份有限公司 |
Pi3k抑制剂和c-met抑制剂的组合
|
CN102952086B
(zh)
*
|
2012-09-28 |
2013-08-28 |
天津科创医药中间体技术生产力促进有限公司 |
一种2-吗啉基取代嘧啶类化合物的制备方法
|
US9394257B2
(en)
|
2012-10-16 |
2016-07-19 |
Tolero Pharmaceuticals, Inc. |
PKM2 modulators and methods for their use
|
WO2014064058A1
(en)
|
2012-10-23 |
2014-05-01 |
Novartis Ag |
Improved process for manufacturing 5-(2,6-di-4-morpholinyl-4-pyrimidinyl)-4-trifluoromethylpyridin-2-amine
|
US9296733B2
(en)
|
2012-11-12 |
2016-03-29 |
Novartis Ag |
Oxazolidin-2-one-pyrimidine derivative and use thereof for the treatment of conditions, diseases and disorders dependent upon PI3 kinases
|
BR112015011147A8
(pt)
|
2012-11-16 |
2019-10-01 |
Merck Sharp & Dohme |
composto, composição farmacêutica, e, uso do referido composto
|
WO2014093230A2
(en)
*
|
2012-12-10 |
2014-06-19 |
Merck Patent Gmbh |
Compositions and methods for the production of pyrimidine and pyridine compounds with btk inhibitory activity
|
EP2742940B1
(de)
|
2012-12-13 |
2017-07-26 |
IP Gesellschaft für Management mbH |
(R)-3-(6-(4-methylphenyl)-pyridin-3-yloxy)-l-aza-bicyclo-[2.2.2]octane Fumarat zur einmal, zweimal oder dreimal täglichen Verabreichung
|
CN104245693B
(zh)
*
|
2012-12-14 |
2016-08-24 |
上海恒瑞医药有限公司 |
嘧啶类衍生物及其可药用盐、其制备方法及其在医药上的应用
|
PT2958943T
(pt)
|
2013-02-20 |
2019-12-17 |
Novartis Ag |
Tratamento do cancro usando recetor de antigénios quiméricos anti-egfrviii humanizados
|
GB201303109D0
(en)
*
|
2013-02-21 |
2013-04-10 |
Domainex Ltd |
Novel pyrimidine compounds
|
WO2014136048A1
(en)
*
|
2013-03-06 |
2014-09-12 |
Novartis Ag |
Formulations of organic compounds
|
CN107200749B
(zh)
|
2013-03-12 |
2019-09-03 |
沃泰克斯药物股份有限公司 |
Dna-pk抑制剂
|
US9498532B2
(en)
|
2013-03-13 |
2016-11-22 |
Novartis Ag |
Antibody drug conjugates
|
ES2665619T3
(es)
|
2013-03-14 |
2018-04-26 |
Novartis Ag |
3-Pirimidin-4-il-oxazolidin-2-onas como inhibidores de IDH mutante
|
US9242969B2
(en)
|
2013-03-14 |
2016-01-26 |
Novartis Ag |
Biaryl amide compounds as kinase inhibitors
|
US10202356B2
(en)
|
2013-03-14 |
2019-02-12 |
Tolero Pharmaceuticals, Inc. |
JAK2 and ALK2 inhibitors and methods for their use
|
CN105007950B
(zh)
|
2013-03-15 |
2019-01-15 |
诺华股份有限公司 |
抗体药物缀合物
|
SG10201906270VA
(en)
|
2013-03-21 |
2019-08-27 |
Novartis Ag |
Combination therapy comprising a b-raf inhibitor and a second inhibitor
|
US9611283B1
(en)
|
2013-04-10 |
2017-04-04 |
Ariad Pharmaceuticals, Inc. |
Methods for inhibiting cell proliferation in ALK-driven cancers
|
CN105164114B
(zh)
*
|
2013-05-01 |
2018-03-23 |
豪夫迈·罗氏有限公司 |
C‑连接的杂环烷基取代的嘧啶类和它们的用途
|
CN110003178B
(zh)
*
|
2013-05-01 |
2022-02-25 |
豪夫迈·罗氏有限公司 |
二杂芳基化合物及其用途
|
RU2672555C2
(ru)
*
|
2013-05-07 |
2018-11-16 |
Новартис Аг |
Комбинация ингибитора pi3 киназы с паклитакселом для использования при лечении или предотвращении рака головы и шеи
|
KR20160018531A
(ko)
|
2013-06-11 |
2016-02-17 |
노파르티스 아게 |
Pi3k 억제제 및 미세관 탈안정화제의 제약 조합물
|
JP2016522247A
(ja)
|
2013-06-18 |
2016-07-28 |
ノバルティス アーゲー |
組合せ医薬
|
WO2015019320A1
(en)
|
2013-08-08 |
2015-02-12 |
Novartis Ag |
Pim kinase inhibitor combinations
|
BR112016002465B1
(pt)
|
2013-08-14 |
2022-09-20 |
Novartis Ag |
Combinação farmacêutica e seu uso
|
WO2015022657A1
(en)
|
2013-08-16 |
2015-02-19 |
Novartis Ag |
Pharmaceutical combinations
|
MX2016003046A
(es)
|
2013-09-09 |
2016-09-08 |
Melinta Therapeutics Inc |
Compuestos antimicrobianos y métodos de fabricación y utilización de los mismos.
|
KR20160070066A
(ko)
|
2013-09-09 |
2016-06-17 |
멜린타 테라퓨틱스, 인크. |
항균 화합물, 및 이의 제조 방법 및 이용 방법
|
CN103483345B
(zh)
*
|
2013-09-25 |
2016-07-06 |
中山大学 |
Pi3k激酶抑制剂、包含其的药物组合物及其应用
|
EP3049442A4
(de)
|
2013-09-26 |
2017-06-28 |
Costim Pharmaceuticals Inc. |
Verfahren zur behandlung von blutkrebs
|
EP3057953B1
(de)
|
2013-10-17 |
2018-08-15 |
Vertex Pharmaceuticals Incorporated |
Co-kristalle von (s)-n-methyl-8-(1-((2'-methyl-[4,5'-bipyrimidin]-6-yl)amino)propan-2-yl)chinolin-4-carboxamid und deuterierten derivaten davon als dna-pk-hemmer
|
US20160331755A1
(en)
*
|
2014-01-15 |
2016-11-17 |
Samit Hirawat |
Pharmaceutical Combinations
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
CA2940666C
(en)
|
2014-02-28 |
2022-08-23 |
Nimbus Lakshmi, Inc. |
Tyk2 inhibitors and uses thereof
|
CN106103484B
(zh)
|
2014-03-14 |
2021-08-20 |
诺华股份有限公司 |
针对lag-3的抗体分子及其用途
|
RU2688665C2
(ru)
|
2014-04-22 |
2019-05-22 |
Университет Базель |
Новый способ получения производных триазина, пиримидина и пиридина
|
WO2016001789A1
(en)
*
|
2014-06-30 |
2016-01-07 |
Pfizer Inc. |
Pyrimidine derivatives as pi3k inhibitors for use in the treatment of cancer
|
WO2016001341A1
(en)
*
|
2014-07-03 |
2016-01-07 |
F. Hoffmann-La Roche Ag |
Sulfonylaminopyridine compounds, compositions and methods of use
|
WO2016020791A1
(en)
|
2014-08-05 |
2016-02-11 |
Novartis Ag |
Ckit antibody drug conjugates
|
US11311512B2
(en)
|
2014-08-12 |
2022-04-26 |
Monash University |
Lymph directing prodrugs
|
TN2016000577A1
(en)
|
2014-08-12 |
2018-04-04 |
Novartis Ag |
Anti-cdh6 antibody drug conjugates
|
CN105330699B
(zh)
*
|
2014-08-13 |
2018-12-04 |
山东汇睿迪生物技术有限公司 |
一种含磷吡啶并[2,3-d]嘧啶-7-酮类化合物或其药学上可接受的盐、药物组合物及其应用
|
CN104151256B
(zh)
*
|
2014-08-14 |
2016-08-24 |
西安交通大学 |
二取代苯甲酰胺类化合物及其合成方法和应用
|
US9993551B2
(en)
|
2014-09-13 |
2018-06-12 |
Novartis Ag |
Combination therapies of EGFR inhibitors
|
CN105461714B
(zh)
*
|
2014-09-29 |
2017-11-28 |
山东轩竹医药科技有限公司 |
并环类pi3k抑制剂
|
KR20170066546A
(ko)
|
2014-10-03 |
2017-06-14 |
노파르티스 아게 |
조합 요법
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
CU20170052A7
(es)
|
2014-10-14 |
2017-11-07 |
Dana Farber Cancer Inst Inc |
Moléculas de anticuerpo que se unen a pd-l1
|
MA40933A
(fr)
|
2014-11-11 |
2017-09-19 |
Piqur Therapeutics Ag |
Difluorométhyl-aminopyridines et difluorométhyl-aminopyrimidines
|
JP6831783B2
(ja)
|
2014-11-14 |
2021-02-17 |
ノバルティス アーゲー |
抗体薬物コンジュゲート
|
CN105085476B
(zh)
*
|
2014-11-24 |
2018-03-09 |
苏州晶云药物科技有限公司 |
5‑[2,6‑二(4‑吗啉基)‑4‑嘧啶基]‑4‑(三氟甲基)‑2‑吡啶胺二盐酸盐的晶型及其制备方法
|
JP6847835B2
(ja)
*
|
2014-12-12 |
2021-03-24 |
ザ ジェネラル ホスピタル コーポレイション |
乳がん脳転移の処置
|
AU2015366357B2
(en)
*
|
2014-12-17 |
2018-07-19 |
Shanghai Haiyan Pharmaceutical Technology Co. Ltd. |
2-morpholin-4,6-disubstituted pyrimidine derivative, and preparation method and pharmaceutical use thereof
|
EP3233918A1
(de)
|
2014-12-19 |
2017-10-25 |
Novartis AG |
Kombinationstherapien
|
NZ731664A
(en)
|
2014-12-23 |
2024-02-23 |
Novartis Ag |
Triazolopyrimidine compounds and uses thereof
|
CN105832741A
(zh)
*
|
2015-01-16 |
2016-08-10 |
复旦大学 |
Pi3k抑制剂与紫杉醇的药物组合物及其在制备抗肿瘤药物中的应用
|
TWI788655B
(zh)
|
2015-02-27 |
2023-01-01 |
美商林伯士拉克許米公司 |
酪胺酸蛋白質激酶2(tyk2)抑制劑及其用途
|
JP2018510138A
(ja)
|
2015-02-27 |
2018-04-12 |
カーテナ ファーマシューティカルズ,インク. |
Olig2活性の阻害
|
MY190404A
(en)
|
2015-03-10 |
2022-04-21 |
Aduro Biotech Inc |
Compositions and methods for activating "stimulator of interferon gene"-dependent signalling
|
SG11201707346RA
(en)
|
2015-03-11 |
2017-10-30 |
Melinta Therapeutics Inc |
Antimicrobial compounds and methods of making and using the same
|
US9481665B2
(en)
*
|
2015-03-13 |
2016-11-01 |
Yong Xu |
Process for preparing PI3K inhibitor buparsilib
|
JP6695353B2
(ja)
|
2015-03-25 |
2020-05-20 |
ノバルティス アーゲー |
Fgfr4阻害剤としてのホルミル化n−複素環式誘導体
|
EP3273959A1
(de)
*
|
2015-03-25 |
2018-01-31 |
Novartis Ag |
Pharmazeutische kombinationen
|
WO2016203432A1
(en)
|
2015-06-17 |
2016-12-22 |
Novartis Ag |
Antibody drug conjugates
|
WO2017004134A1
(en)
|
2015-06-29 |
2017-01-05 |
Nimbus Iris, Inc. |
Irak inhibitors and uses thereof
|
WO2017004537A1
(en)
|
2015-07-02 |
2017-01-05 |
Centrexion Therapeutics Corporation |
(4-((3r,4r)-3-methoxytetrahydro-pyran-4-ylamino)piperidin-1-yl)(5-methyl-6-(((2r,6s)-6-(p-tolyl)tetrahydro-2h-pyran-2-yl)methylamino)pyrimidin-4yl)methanone citrate
|
WO2017009751A1
(en)
|
2015-07-15 |
2017-01-19 |
Pfizer Inc. |
Pyrimidine derivatives
|
EP3316902A1
(de)
|
2015-07-29 |
2018-05-09 |
Novartis AG |
Kombinationstherapien mit antikörpermolekülen gegen tim-3
|
SI3317301T1
(sl)
|
2015-07-29 |
2021-10-29 |
Novartis Ag |
Kombinirane terapije, ki obsegajo molekule protitelesa na LAG-3
|
JP2018528206A
(ja)
|
2015-08-28 |
2018-09-27 |
ノバルティス アーゲー |
Mdm2阻害剤およびその組み合わせ物
|
CN105001151B
(zh)
*
|
2015-08-28 |
2017-07-14 |
苏州明锐医药科技有限公司 |
布帕尼西中间体及其制备方法
|
US10023571B2
(en)
|
2015-09-02 |
2018-07-17 |
Nimbus Lakshimi, Inc. |
TYK2 inhibitors and uses thereof
|
AU2016318229A1
(en)
|
2015-09-08 |
2018-03-29 |
Monash University |
Lymph directing prodrugs
|
US10683308B2
(en)
|
2015-09-11 |
2020-06-16 |
Navitor Pharmaceuticals, Inc. |
Rapamycin analogs and uses thereof
|
JP6800968B2
(ja)
|
2015-10-23 |
2020-12-16 |
ナビター ファーマシューティカルズ, インコーポレイテッド |
セストリン−gator2相互作用のモジュレーターおよびその使用
|
MA44334A
(fr)
|
2015-10-29 |
2018-09-05 |
Novartis Ag |
Conjugués d'anticorps comprenant un agoniste du récepteur de type toll
|
AU2016347881A1
(en)
|
2015-11-02 |
2018-05-10 |
Novartis Ag |
Dosage regimen for a phosphatidylinositol 3-kinase inhibitor
|
BR112018008904A2
(pt)
|
2015-11-03 |
2018-11-27 |
Janssen Biotech Inc |
anticorpos que se ligam especificamente a tim-3 e seus usos
|
RU2018123524A
(ru)
|
2015-12-03 |
2020-01-09 |
Новартис Аг |
Фармацевтическая диагностика
|
EP3389664A4
(de)
|
2015-12-14 |
2020-01-08 |
Raze Therapeutics Inc. |
Koffeininhibitoren von mthfd2 und verwendungen dafür
|
CN106883185B
(zh)
*
|
2015-12-15 |
2021-07-09 |
重庆博腾制药科技股份有限公司 |
一种4-氯-2-三氟甲基嘧啶的制备方法
|
CA3007671A1
(en)
|
2015-12-17 |
2017-06-22 |
Novartis Ag |
Antibody molecules to pd-1 and uses thereof
|
US11014882B2
(en)
|
2016-03-09 |
2021-05-25 |
Raze Therapeutics, Inc. |
3-phosphoglycerate dehydrogenase inhibitors and uses thereof
|
PT3426243T
(pt)
|
2016-03-09 |
2021-08-19 |
Raze Therapeutics Inc |
Inibidores de 3-fosfoglicerato desidrogenase e utilizações dos mesmos
|
JP2019510785A
(ja)
|
2016-04-08 |
2019-04-18 |
エックス4 ファーマシューティカルズ, インコーポレイテッド |
癌を処置する方法
|
EP3231799A1
(de)
*
|
2016-04-14 |
2017-10-18 |
Universität Basel |
4-(azetidin-1-yl)pyrimidin- derivate mit anti-mitotischer und anti-proliferativer aktivität
|
CN109414415B
(zh)
|
2016-05-18 |
2023-05-02 |
拓客股份有限公司 |
皮肤病变的治疗
|
SG11201809792TA
(en)
*
|
2016-05-18 |
2018-12-28 |
Piqur Therapeutics Ag |
Treatment of neurological disorders
|
CN108430987B
(zh)
*
|
2016-06-02 |
2021-06-18 |
上海海雁医药科技有限公司 |
Pi3k抑制剂及其药学上可接受的盐和多晶型物及其应用
|
CN109906224B
(zh)
|
2016-06-20 |
2022-02-25 |
诺华股份有限公司 |
***吡啶化合物及其应用
|
WO2017221100A1
(en)
|
2016-06-20 |
2017-12-28 |
Novartis Ag |
Imidazopyrimidine compounds useful for the treatment of cancer
|
US11091489B2
(en)
|
2016-06-20 |
2021-08-17 |
Novartis Ag |
Crystalline forms of a triazolopyrimidine compound
|
WO2017223243A1
(en)
|
2016-06-21 |
2017-12-28 |
X4 Pharmaceuticals, Inc. |
Cxcr4 inhibitors and uses thereof
|
EP3471726A4
(de)
|
2016-06-21 |
2019-10-09 |
X4 Pharmaceuticals, Inc. |
Cxcr4-inhibitoren und verwendungen davon
|
US10759796B2
(en)
|
2016-06-21 |
2020-09-01 |
X4 Pharmaceuticals, Inc. |
CXCR4 inhibitors and uses thereof
|
EP3507367A4
(de)
|
2016-07-05 |
2020-03-25 |
Aduro BioTech, Inc. |
Cyclisches dinukleotidverbindungen mit eingeschlossenen nukleinsäuren und verwendungen davon
|
CN106905294A
(zh)
*
|
2016-07-08 |
2017-06-30 |
苏州科睿思制药有限公司 |
5‑[2,6‑二(4‑吗啉基)‑4‑嘧啶基]‑4‑(三氟甲基)‑2‑吡啶胺的晶型及其制备方法
|
TW201815418A
(zh)
|
2016-09-27 |
2018-05-01 |
Vertex Pharma |
使用dna破壞劑及dna-pk抑制劑之組合治療癌症的方法
|
JP2019536471A
(ja)
|
2016-09-27 |
2019-12-19 |
セロ・セラピューティクス・インコーポレイテッドCERO Therapeutics, Inc. |
キメラエンガルフメント受容体分子
|
EP3526222B1
(de)
|
2016-10-14 |
2022-08-17 |
Nimbus Lakshmi, Inc. |
Tyk2-inhibitoren und verwendungen davon
|
EP3528816A4
(de)
|
2016-10-21 |
2020-04-08 |
Nimbus Lakshmi, Inc. |
Tyk2-inhibitoren und verwendungen davon
|
WO2018089499A1
(en)
|
2016-11-08 |
2018-05-17 |
Navitor Pharmaceuticals, Inc. |
PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF
|
WO2018092064A1
(en)
|
2016-11-18 |
2018-05-24 |
Novartis Ag |
Combinations of mdm2 inhibitors and bcl-xl inhibitors
|
CA3043768A1
(en)
|
2016-11-29 |
2018-06-07 |
PureTech Health LLC |
Exosomes for delivery of therapeutic agents
|
US11091451B2
(en)
|
2016-12-05 |
2021-08-17 |
Raze Therapeutics, Inc. |
SHMT inhibitors and uses thereof
|
JP2020502238A
(ja)
|
2016-12-23 |
2020-01-23 |
バイスクルアールディー・リミテッド |
新規連結構造を有するペプチド誘導体
|
EP3565638B8
(de)
|
2017-01-06 |
2024-04-10 |
BicycleRD Limited |
Bizyklische konjugat zur behandlung von krebs
|
JOP20190187A1
(ar)
|
2017-02-03 |
2019-08-01 |
Novartis Ag |
مترافقات عقار جسم مضاد لـ ccr7
|
EP3592868B1
(de)
|
2017-03-06 |
2022-11-23 |
Novartis AG |
Verfahren zur behandlung von krebs mit reduzierter ubb-expression
|
TWI783978B
(zh)
|
2017-03-08 |
2022-11-21 |
美商林伯士拉克許米公司 |
Tyk2抑制劑、其用途及生產方法
|
EP3375784A1
(de)
|
2017-03-14 |
2018-09-19 |
Artax Biopharma Inc. |
Aza-dihydro-acridonderivate
|
EP3375778A1
(de)
|
2017-03-14 |
2018-09-19 |
Artax Biopharma Inc. |
Aryl-piperidinderivate
|
GB201705263D0
(en)
*
|
2017-03-31 |
2017-05-17 |
Probiodrug Ag |
Novel inhibitors
|
WO2018185618A1
(en)
|
2017-04-03 |
2018-10-11 |
Novartis Ag |
Anti-cdh6 antibody drug conjugates and anti-gitr antibody combinations and methods of treatment
|
WO2018191146A1
(en)
|
2017-04-10 |
2018-10-18 |
Navitor Pharmaceuticals, Inc. |
Heteroaryl rheb inhibitors and uses thereof
|
WO2018200625A1
(en)
|
2017-04-26 |
2018-11-01 |
Navitor Pharmaceuticals, Inc. |
Modulators of sestrin-gator2 interaction and uses thereof
|
US10857196B2
(en)
|
2017-04-27 |
2020-12-08 |
Bicycletx Limited |
Bicyclic peptide ligands and uses thereof
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
MX2019013862A
(es)
|
2017-05-23 |
2020-01-20 |
Mei Pharma Inc |
Terapia de combinacion.
|
WO2018215937A1
(en)
|
2017-05-24 |
2018-11-29 |
Novartis Ag |
Interleukin-7 antibody cytokine engrafted proteins and methods of use in the treatment of cancer
|
US20200362058A1
(en)
|
2017-05-24 |
2020-11-19 |
Novartis Ag |
Antibody-cytokine engrafted proteins and methods of use
|
US20200270334A1
(en)
|
2017-05-24 |
2020-08-27 |
Novartis Ag |
Antibody-cytokine engrafted proteins and methods of use in the treatment of cancer
|
JP7433910B2
(ja)
|
2017-06-22 |
2024-02-20 |
ノバルティス アーゲー |
Cd73に対する抗体分子及びその使用
|
WO2018237173A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
ANTIBODY MOLECULES DIRECTED AGAINST CD73 AND CORRESPONDING USES
|
WO2019002842A1
(en)
|
2017-06-26 |
2019-01-03 |
Bicyclerd Limited |
BICYCLIC PEPTIDE LIGANDS WITH DETECTABLE FRACTIONS AND USES THEREOF
|
JP7216705B2
(ja)
|
2017-07-28 |
2023-02-02 |
ニンバス ラクシュミ, インコーポレイテッド |
Tyk2阻害剤およびその使用方法
|
EP3668887A1
(de)
|
2017-08-14 |
2020-06-24 |
Bicyclerd Limited |
Bicyclische peptid-ligand-sting-konjugate und verwendungen davon
|
WO2019034868A1
(en)
|
2017-08-14 |
2019-02-21 |
Bicyclerd Limited |
CONJUGATES PEPTIDE BICYCLIC-LIGAND PPR-A AND USES THEREOF
|
MX2020001727A
(es)
|
2017-08-14 |
2020-03-20 |
Mei Pharma Inc |
Terapia de combinacion.
|
US10800774B2
(en)
*
|
2017-08-17 |
2020-10-13 |
Board Of Regents, The University Of Texas System |
Heterocyclic inhibitors of ATR kinase
|
EP4306524A2
(de)
|
2017-08-29 |
2024-01-17 |
PureTech LYT, Inc. |
An das lymphatische system gerichtete lipidprodrugs
|
US11883497B2
(en)
|
2017-08-29 |
2024-01-30 |
Puretech Lyt, Inc. |
Lymphatic system-directing lipid prodrugs
|
CA3073073A1
(en)
|
2017-09-08 |
2019-03-14 |
F. Hoffmann-La Roche Ag |
Diagnostic and therapeutic methods for cancer
|
US11358948B2
(en)
|
2017-09-22 |
2022-06-14 |
Kymera Therapeutics, Inc. |
CRBN ligands and uses thereof
|
IL307995A
(en)
|
2017-09-22 |
2023-12-01 |
Kymera Therapeutics Inc |
Protein compounds and their uses
|
CA3073421A1
(en)
|
2017-09-26 |
2019-04-04 |
Daniel Mark COREY |
Chimeric engulfment receptor molecules and methods of use
|
CN109651341A
(zh)
*
|
2017-10-11 |
2019-04-19 |
上海医药工业研究院 |
二吗啉氰基嘧(吡)啶类衍生物及作为抗肿瘤药物应用
|
US11351156B2
(en)
|
2017-10-13 |
2022-06-07 |
Inserm |
Combination treatment of pancreatic cancer
|
WO2019101871A1
(en)
|
2017-11-23 |
2019-05-31 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
A new marker for predicting the sensitivity to pi3k inhibitors
|
US11304954B2
(en)
|
2017-12-19 |
2022-04-19 |
Puretech Lyt, Inc. |
Lipid prodrugs of mycophenolic acid and uses thereof
|
US11608345B1
(en)
|
2017-12-19 |
2023-03-21 |
Puretech Lyt, Inc. |
Lipid prodrugs of rapamycin and its analogs and uses thereof
|
TWI825046B
(zh)
|
2017-12-19 |
2023-12-11 |
英商拜西可泰克斯有限公司 |
Epha2特用之雙環胜肽配位基
|
WO2019126378A1
(en)
|
2017-12-19 |
2019-06-27 |
Ariya Therapeutics, Inc. |
Lipid prodrugs of mycophenolic acid and uses thereof
|
GB201721265D0
(en)
|
2017-12-19 |
2018-01-31 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for EphA2
|
US11667651B2
(en)
|
2017-12-22 |
2023-06-06 |
Hibercell, Inc. |
Aminopyridine derivatives as phosphatidylinositol phosphate kinase inhibitors
|
EP3728230A1
(de)
*
|
2017-12-22 |
2020-10-28 |
Ravenna Pharmaceuticals, Inc. |
Aryl-bipyridin-aminderivate als phosphatidylinositol-phosphatkinase-inhibitoren
|
MX2020006812A
(es)
|
2017-12-26 |
2020-11-06 |
Kymera Therapeutics Inc |
Degradadores de cinasas asociadas al receptor de interleucina-1 (irak) y usos de los mismos.
|
US11512080B2
(en)
|
2018-01-12 |
2022-11-29 |
Kymera Therapeutics, Inc. |
CRBN ligands and uses thereof
|
EP3737666A4
(de)
|
2018-01-12 |
2022-01-05 |
Kymera Therapeutics, Inc. |
Proteinabbaumittel und verwendungen davon
|
EP3746075A4
(de)
|
2018-01-29 |
2021-09-08 |
Merck Patent GmbH |
Gcn2-inhibitoren und verwendungen davon
|
KR20200115620A
(ko)
|
2018-01-29 |
2020-10-07 |
메르크 파텐트 게엠베하 |
Gcn2 억제제 및 이의 용도
|
WO2019169001A1
(en)
|
2018-02-27 |
2019-09-06 |
Artax Biopharma Inc. |
Chromene derivatives as inhibitors of tcr-nck interaction
|
US20210087251A1
(en)
|
2018-03-28 |
2021-03-25 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
RU2020135107A
(ru)
|
2018-03-28 |
2022-04-29 |
Серо Терапьютикс, Инк. |
Клеточные иммунотерапевтические композиции и их применения
|
US20210024607A1
(en)
|
2018-03-28 |
2021-01-28 |
Cero Therapeutics, Inc. |
Expression vectors for chimeric engulfment receptors, genetically modified host cells, and uses thereof
|
MX2020010437A
(es)
|
2018-04-05 |
2021-01-29 |
Sumitomo Pharma Oncology Inc |
Inhibidores de axl cinasa y uso de los mismos.
|
CN111936469A
(zh)
*
|
2018-04-06 |
2020-11-13 |
日本曹达株式会社 |
(杂)芳基磺酰胺化合物和有害生物防除剂
|
US11236079B2
(en)
|
2018-04-10 |
2022-02-01 |
Neuropore Therapies, Inc. |
Morpholine derivates as inhibitors of Vps34
|
MX2020010576A
(es)
*
|
2018-04-10 |
2021-03-02 |
Neuropore Therapies Inc |
Derivados tri sustituidos de arilo y heteroarilo como moduladores de p13-kinasa y rutas de autofagia.
|
CA3097774A1
(en)
|
2018-04-24 |
2019-10-31 |
Vertex Pharmaceuticals Incorporated |
Pteridinone compounds and uses thereof
|
ES2919572T3
(es)
|
2018-04-24 |
2022-07-27 |
Merck Patent Gmbh |
Compuestos antiproliferación y usos de los mismos
|
TW202015726A
(zh)
|
2018-05-30 |
2020-05-01 |
瑞士商諾華公司 |
Entpd2抗體、組合療法、及使用該等抗體和組合療法之方法
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
JP7382353B2
(ja)
|
2018-06-15 |
2023-11-16 |
ヤンセン ファーマシューティカ エヌ.ベー. |
ラパマイシン類似体およびその使用
|
CN108864067B
(zh)
*
|
2018-06-20 |
2020-05-12 |
郑州大学 |
一种2-炔丙巯基-5-氰基嘧啶类衍生物及其制备方法和应用
|
GB201810316D0
(en)
|
2018-06-22 |
2018-08-08 |
Bicyclerd Ltd |
Peptide ligands for binding to EphA2
|
US11180531B2
(en)
|
2018-06-22 |
2021-11-23 |
Bicycletx Limited |
Bicyclic peptide ligands specific for Nectin-4
|
WO2020010177A1
(en)
|
2018-07-06 |
2020-01-09 |
Kymera Therapeutics, Inc. |
Tricyclic crbn ligands and uses thereof
|
CA3103995A1
(en)
|
2018-07-26 |
2020-01-30 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Methods for treating diseases associated with abnormal acvr1 expression and acvr1 inhibitors for use in the same
|
LT3837256T
(lt)
|
2018-08-17 |
2023-06-12 |
Novartis Ag |
Karbamido junginiai ir kompozicijos kaip smarca2 / brm atfazės inhibitoriai
|
US10548889B1
(en)
|
2018-08-31 |
2020-02-04 |
X4 Pharmaceuticals, Inc. |
Compositions of CXCR4 inhibitors and methods of preparation and use
|
EP3846793B1
(de)
|
2018-09-07 |
2024-01-24 |
PIC Therapeutics, Inc. |
Eif4e-inhibitoren und verwendungen davon
|
WO2020081508A1
(en)
|
2018-10-15 |
2020-04-23 |
Nimbus Lakshmi, Inc. |
Tyk2 inhibitors and uses thereof
|
CN112955459A
(zh)
|
2018-10-23 |
2021-06-11 |
拜斯科技术开发有限公司 |
双环肽配体和其用途
|
AU2019364542A1
(en)
|
2018-10-24 |
2021-06-10 |
Navitor Pharmaceuticals, Inc. |
Polymorphic compounds and uses thereof
|
EP3873532A1
(de)
|
2018-10-31 |
2021-09-08 |
Novartis AG |
Dc-sign-antikörper-arzneimittelkonjugate
|
US11352350B2
(en)
|
2018-11-30 |
2022-06-07 |
Kymera Therapeutics, Inc. |
IRAK degraders and uses thereof
|
AU2019389025A1
(en)
|
2018-11-30 |
2021-06-17 |
Takeda Pharmaceutical Company Limited |
TYK2 inhibitors and uses thereof
|
EP3670659A1
(de)
|
2018-12-20 |
2020-06-24 |
Abivax |
Biomarker und verwendungen bei der behandlung von viralen infektionen, entzündlichen oder krebserkrankungen
|
BR112021011894A2
(pt)
|
2018-12-21 |
2021-09-08 |
Daiichi Sankyo Company, Limited |
Composição farmacêutica
|
BR112021011900A2
(pt)
|
2018-12-21 |
2021-09-08 |
Novartis Ag |
Anticorpos para pmel17 e conjugados dos mesmos
|
CN109705033B
(zh)
*
|
2019-01-22 |
2021-03-30 |
杭州壹瑞医药科技有限公司 |
N-杂芳基磺酰胺类衍生物及制备和应用
|
CN109651297B
(zh)
*
|
2019-01-22 |
2022-05-27 |
杭州壹瑞医药科技有限公司 |
一种n-苄基-n-芳基磺酰胺类衍生物及制备和应用
|
CN113348021A
(zh)
|
2019-01-23 |
2021-09-03 |
林伯士拉克许米公司 |
Tyk2抑制剂和其用途
|
EP3924351A4
(de)
|
2019-02-12 |
2022-12-21 |
Sumitomo Pharma Oncology, Inc. |
Formulierungen mit heterocyclischen proteinkinaseinhibitoren
|
WO2020165600A1
(en)
|
2019-02-14 |
2020-08-20 |
Bicycletx Limited |
Bicyclic peptide ligand sting conjugates and uses thereof
|
AU2020245437A1
(en)
|
2019-03-22 |
2021-09-30 |
Sumitomo Pharma Oncology, Inc. |
Compositions comprising PKM2 modulators and methods of treatment using the same
|
JP2022528887A
(ja)
|
2019-04-02 |
2022-06-16 |
バイスクルテクス・リミテッド |
バイシクルトキシンコンジュゲートおよびその使用
|
KR20220006139A
(ko)
|
2019-04-05 |
2022-01-14 |
카이메라 쎄라퓨틱스 인코포레이티드 |
Stat 분해제 및 이의 용도
|
JP2022534425A
(ja)
|
2019-05-31 |
2022-07-29 |
イケナ オンコロジー, インコーポレイテッド |
Tead阻害剤およびその使用
|
WO2021001431A1
(en)
|
2019-07-02 |
2021-01-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of pi3ka-selective inhibitors for treating metastatic disease in patients suffering from pancreatic cancer
|
WO2021001427A1
(en)
|
2019-07-02 |
2021-01-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the prophylactic treatment of cancer in patients suffering from pancreatitis
|
EP3993707A1
(de)
|
2019-07-02 |
2022-05-11 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Verwendung von ultraschneller elastizitätsbildgebung zur detektion von pankreaskrebs
|
WO2021003417A1
(en)
|
2019-07-03 |
2021-01-07 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Tyrosine kinase non-receptor 1 (tnk1) inhibitors and uses thereof
|
AU2020345962A1
(en)
|
2019-09-11 |
2022-03-31 |
Vincere Biosciences, Inc. |
USP30 inhibitors and uses thereof
|
JP2022547719A
(ja)
|
2019-09-13 |
2022-11-15 |
ニンバス サターン, インコーポレイテッド |
Hpk1アンタゴニストおよびその使用
|
JP2022548881A
(ja)
|
2019-09-18 |
2022-11-22 |
ノバルティス アーゲー |
Entpd2抗体、組合せ療法並びに抗体及び組合せ療法を使用する方法
|
EP4038097A1
(de)
|
2019-10-03 |
2022-08-10 |
Cero Therapeutics, Inc. |
Chimäre tim4-rezeptoren und verwendungen davon
|
US11723890B2
(en)
|
2019-11-01 |
2023-08-15 |
Navitor Pharmaceuticals, Inc. |
Methods of treatment using an mTORC1 modulator
|
CN115209897A
(zh)
|
2019-12-05 |
2022-10-18 |
安纳库利亚治疗公司 |
雷帕霉素类似物及其用途
|
IL293917A
(en)
|
2019-12-17 |
2022-08-01 |
Kymera Therapeutics Inc |
Iraq joints and their uses
|
US11591332B2
(en)
|
2019-12-17 |
2023-02-28 |
Kymera Therapeutics, Inc. |
IRAK degraders and uses thereof
|
CA3162502A1
(en)
|
2019-12-23 |
2021-07-01 |
Yi Zhang |
Smarca degraders and uses thereof
|
WO2021159993A1
(en)
*
|
2020-02-14 |
2021-08-19 |
Pharmablock Sciences (Nanjing) , Inc. |
Inhibitors of interleukin-1 receptor associated kinase (irak) /fms-like receptor tyrosine kinase (flt3), pharmaceutical products thereof, and methods thereof
|
TW202146393A
(zh)
|
2020-03-03 |
2021-12-16 |
美商皮克醫療公司 |
Eif4e抑制劑及其用途
|
EP4121043A1
(de)
|
2020-03-19 |
2023-01-25 |
Kymera Therapeutics, Inc. |
Mdm2-degrader und verwendungen davon
|
US20230181756A1
(en)
|
2020-04-30 |
2023-06-15 |
Novartis Ag |
Ccr7 antibody drug conjugates for treating cancer
|
TW202210483A
(zh)
|
2020-06-03 |
2022-03-16 |
美商凱麥拉醫療公司 |
Irak降解劑之結晶型
|
KR20210158019A
(ko)
|
2020-06-23 |
2021-12-30 |
주식회사 온코빅스 |
포스파티딜이노시톨 3-키나제(pi3k) 억제제로써 pten 과오종 증후군에 의한 종양 세포의 성장 또는 증식을 억제하는데 유용한 신규한 피리미딘 유도체 및 이의 약제학적으로 허용가능한 염, 및 이를 유효성분으로 함유하는 약제학적 조성물
|
AR123185A1
(es)
|
2020-08-10 |
2022-11-09 |
Novartis Ag |
Compuestos y composiciones para inhibir ezh2
|
WO2022036285A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Compositions and methods for treating cancer with chimeric tim receptors in combination with inhibitors of poly (adp-ribose) polymerase
|
WO2022036265A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Chimeric tim receptors and uses thereof
|
WO2022036287A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Anti-cd72 chimeric receptors and uses thereof
|
CN116234931A
(zh)
|
2020-08-17 |
2023-06-06 |
拜斯科技术开发有限公司 |
对nectin-4具有特异性的双环缀合物及其用途
|
WO2022043558A1
(en)
|
2020-08-31 |
2022-03-03 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
WO2022043556A1
(en)
|
2020-08-31 |
2022-03-03 |
Novartis Ag |
Stable radiopharmaceutical composition
|
WO2022043557A1
(en)
|
2020-08-31 |
2022-03-03 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
TW202227089A
(zh)
|
2020-11-30 |
2022-07-16 |
大陸商杭州阿諾生物醫藥科技有限公司 |
用於治療pik3ca突變癌症的組合療法
|
WO2022120353A1
(en)
|
2020-12-02 |
2022-06-09 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
EP4255895A1
(de)
|
2020-12-02 |
2023-10-11 |
Ikena Oncology, Inc. |
Tead-hemmer und verwendungen davon
|
TW202237119A
(zh)
|
2020-12-10 |
2022-10-01 |
美商住友製藥腫瘤公司 |
Alk﹘5抑制劑和彼之用途
|
US20230113202A1
(en)
|
2021-02-02 |
2023-04-13 |
Liminal Biosciences Limited |
Gpr84 antagonists and uses thereof
|
CN116888116A
(zh)
|
2021-02-02 |
2023-10-13 |
里米诺生物科学有限公司 |
Gpr84拮抗剂和其用途
|
TW202245789A
(zh)
|
2021-02-15 |
2022-12-01 |
美商凱麥拉醫療公司 |
Irak4降解劑及其用途
|
CN117203223A
(zh)
|
2021-02-26 |
2023-12-08 |
凯洛尼亚疗法有限公司 |
淋巴细胞靶向慢病毒载体
|
EP4301756A1
(de)
|
2021-03-05 |
2024-01-10 |
Nimbus Saturn, Inc. |
Hpk1-antagonisten und verwendungen davon
|
KR20230158659A
(ko)
*
|
2021-03-18 |
2023-11-21 |
쑤저우 궈쾅 팜테크 코포레이션 리미티드 |
Ctla-4 소분자 분해제 및 그 응용
|
TW202309022A
(zh)
|
2021-04-13 |
2023-03-01 |
美商努法倫特公司 |
用於治療具egfr突變之癌症之胺基取代雜環
|
WO2022221720A1
(en)
|
2021-04-16 |
2022-10-20 |
Novartis Ag |
Antibody drug conjugates and methods for making thereof
|
AU2022258968A1
(en)
|
2021-04-16 |
2023-10-19 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
WO2023010097A1
(en)
|
2021-07-28 |
2023-02-02 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
US20230134932A1
(en)
|
2021-08-25 |
2023-05-04 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
WO2023028235A1
(en)
|
2021-08-25 |
2023-03-02 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
WO2023107603A1
(en)
*
|
2021-12-08 |
2023-06-15 |
Kineta, Inc. |
Pyrimidines and methods of their use
|
WO2023114984A1
(en)
|
2021-12-17 |
2023-06-22 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
CN114213340B
(zh)
|
2022-02-22 |
2022-06-07 |
北京蓝晶微生物科技有限公司 |
2,4-二氨基嘧啶氧化物的制备方法
|
CN114591326B
(zh)
*
|
2022-02-28 |
2024-02-27 |
上海筛杰生物医药有限公司 |
Cct-251921的中间体及其制备方法
|
WO2023173057A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
WO2023173053A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
WO2023211889A1
(en)
|
2022-04-25 |
2023-11-02 |
Ikena Oncology, Inc. |
Polymorphic compounds and uses thereof
|
US11878958B2
(en)
|
2022-05-25 |
2024-01-23 |
Ikena Oncology, Inc. |
MEK inhibitors and uses thereof
|
WO2024028365A1
(en)
|
2022-08-02 |
2024-02-08 |
Liminal Biosciences Limited |
Substituted pyridone gpr84 antagonists and uses thereof
|
WO2024028363A1
(en)
|
2022-08-02 |
2024-02-08 |
Liminal Biosciences Limited |
Heteroaryl carboxamide and related gpr84 antagonists and uses thereof
|
WO2024028364A1
(en)
|
2022-08-02 |
2024-02-08 |
Liminal Biosciences Limited |
Aryl-triazolyl and related gpr84 antagonists and uses thereof
|