DOP2015000108A - Compuestos de pirrolopirimidina como inhibidores de quinasas - Google Patents
Compuestos de pirrolopirimidina como inhibidores de quinasasInfo
- Publication number
- DOP2015000108A DOP2015000108A DO2015000108A DO2015000108A DOP2015000108A DO P2015000108 A DOP2015000108 A DO P2015000108A DO 2015000108 A DO2015000108 A DO 2015000108A DO 2015000108 A DO2015000108 A DO 2015000108A DO P2015000108 A DOP2015000108 A DO P2015000108A
- Authority
- DO
- Dominican Republic
- Prior art keywords
- compounds
- conditions
- pirrolopirimidine
- inhibitors
- btk inhibitors
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Compuestos que forman enlaces covalentes con la tirosina quinasa de Bruton (Btk). También se describen inhibidores irreversibles de Btk, inhibidores reversibles de Btk y composiciones farmacéuticas que incluyen los compuestos. Además se describen métodos para utilizar los inhibidores Btk, solos o en combinación con otros agentes terapéuticos, para el tratamiento de enfermedades o condiciones autoinmunes, enfermedades o condiciones heteroinmunes, cáncer, incluido el linfoma, y enfermedades o condiciones inflamatorias.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261727031P | 2012-11-15 | 2012-11-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
DOP2015000108A true DOP2015000108A (es) | 2015-06-30 |
Family
ID=50728514
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DO2015000108A DOP2015000108A (es) | 2012-11-15 | 2015-05-12 | Compuestos de pirrolopirimidina como inhibidores de quinasas |
Country Status (24)
Country | Link |
---|---|
US (3) | US9096604B2 (es) |
EP (1) | EP2920180A4 (es) |
JP (1) | JP2015537033A (es) |
KR (1) | KR20150084923A (es) |
CN (1) | CN104854107A (es) |
AR (1) | AR093518A1 (es) |
AU (1) | AU2013344656A1 (es) |
BR (1) | BR112015011171A2 (es) |
CA (1) | CA2890934A1 (es) |
CL (1) | CL2015001268A1 (es) |
CR (1) | CR20150263A (es) |
DO (1) | DOP2015000108A (es) |
EA (1) | EA201590855A1 (es) |
HK (1) | HK1215253A1 (es) |
IL (1) | IL238728A0 (es) |
MA (1) | MA38183A1 (es) |
MX (1) | MX2015006168A (es) |
NI (1) | NI201500067A (es) |
PE (1) | PE20151495A1 (es) |
PH (1) | PH12015501067A1 (es) |
SG (1) | SG11201503842PA (es) |
TN (1) | TN2015000174A1 (es) |
TW (1) | TWI522359B (es) |
WO (1) | WO2014078578A1 (es) |
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-
2013
- 2013-11-14 JP JP2015542791A patent/JP2015537033A/ja active Pending
- 2013-11-14 BR BR112015011171A patent/BR112015011171A2/pt not_active IP Right Cessation
- 2013-11-14 KR KR1020157015148A patent/KR20150084923A/ko not_active Application Discontinuation
- 2013-11-14 MA MA38183A patent/MA38183A1/fr unknown
- 2013-11-14 CA CA2890934A patent/CA2890934A1/en not_active Abandoned
- 2013-11-14 WO PCT/US2013/070164 patent/WO2014078578A1/en active Application Filing
- 2013-11-14 EP EP13854424.2A patent/EP2920180A4/en not_active Withdrawn
- 2013-11-14 AU AU2013344656A patent/AU2013344656A1/en not_active Abandoned
- 2013-11-14 MX MX2015006168A patent/MX2015006168A/es unknown
- 2013-11-14 PE PE2015000625A patent/PE20151495A1/es not_active Application Discontinuation
- 2013-11-14 EA EA201590855A patent/EA201590855A1/ru unknown
- 2013-11-14 SG SG11201503842PA patent/SG11201503842PA/en unknown
- 2013-11-14 CN CN201380059811.2A patent/CN104854107A/zh active Pending
- 2013-11-15 TW TW102141817A patent/TWI522359B/zh not_active IP Right Cessation
- 2013-11-15 US US14/081,053 patent/US9096604B2/en active Active
- 2013-11-18 AR ARP130104233A patent/AR093518A1/es unknown
-
2015
- 2015-05-06 TN TNP2015000174A patent/TN2015000174A1/fr unknown
- 2015-05-08 US US14/708,099 patent/US9540385B2/en active Active
- 2015-05-10 IL IL238728A patent/IL238728A0/en unknown
- 2015-05-12 DO DO2015000108A patent/DOP2015000108A/es unknown
- 2015-05-12 CL CL2015001268A patent/CL2015001268A1/es unknown
- 2015-05-14 NI NI201500067A patent/NI201500067A/es unknown
- 2015-05-14 PH PH12015501067A patent/PH12015501067A1/en unknown
- 2015-05-19 CR CR20150263A patent/CR20150263A/es unknown
-
2016
- 2016-03-18 HK HK16103201.1A patent/HK1215253A1/zh unknown
- 2016-09-09 US US15/261,414 patent/US20160375026A1/en not_active Abandoned
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TN2015000174A1 (en) | 2016-10-03 |
US20140142126A1 (en) | 2014-05-22 |
US20150239897A1 (en) | 2015-08-27 |
TWI522359B (zh) | 2016-02-21 |
CR20150263A (es) | 2015-08-24 |
US9540385B2 (en) | 2017-01-10 |
MX2015006168A (es) | 2015-08-10 |
BR112015011171A2 (pt) | 2017-07-11 |
PE20151495A1 (es) | 2015-10-23 |
HK1215253A1 (zh) | 2016-08-19 |
EP2920180A4 (en) | 2016-04-13 |
EP2920180A1 (en) | 2015-09-23 |
PH12015501067A1 (en) | 2015-08-10 |
MA38183A1 (fr) | 2017-03-31 |
US20160375026A1 (en) | 2016-12-29 |
AR093518A1 (es) | 2015-06-10 |
CL2015001268A1 (es) | 2015-07-10 |
WO2014078578A1 (en) | 2014-05-22 |
AU2013344656A1 (en) | 2015-06-04 |
US9096604B2 (en) | 2015-08-04 |
EA201590855A1 (ru) | 2015-11-30 |
CA2890934A1 (en) | 2014-05-22 |
NI201500067A (es) | 2016-02-15 |
JP2015537033A (ja) | 2015-12-24 |
TW201425315A (zh) | 2014-07-01 |
IL238728A0 (en) | 2015-06-30 |
SG11201503842PA (en) | 2015-06-29 |
CN104854107A (zh) | 2015-08-19 |
KR20150084923A (ko) | 2015-07-22 |
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