TW201613926A - Inhibitors of bruton's tyrosine kinase - Google Patents

Inhibitors of bruton's tyrosine kinase

Info

Publication number
TW201613926A
TW201613926A TW104124894A TW104124894A TW201613926A TW 201613926 A TW201613926 A TW 201613926A TW 104124894 A TW104124894 A TW 104124894A TW 104124894 A TW104124894 A TW 104124894A TW 201613926 A TW201613926 A TW 201613926A
Authority
TW
Taiwan
Prior art keywords
inhibitors
bruton
tyrosine kinase
disclosed
conditions
Prior art date
Application number
TW104124894A
Other languages
Chinese (zh)
Inventor
Wei Chen
Longcheng Wang
Zhaozhong J Jia
Original Assignee
Pharmacyclics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacyclics Llc filed Critical Pharmacyclics Llc
Publication of TW201613926A publication Critical patent/TW201613926A/en

Links

Abstract

Disclosed herein are amido compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
TW104124894A 2014-08-01 2015-07-31 Inhibitors of bruton's tyrosine kinase TW201613926A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462032257P 2014-08-01 2014-08-01

Publications (1)

Publication Number Publication Date
TW201613926A true TW201613926A (en) 2016-04-16

Family

ID=56361135

Family Applications (1)

Application Number Title Priority Date Filing Date
TW104124894A TW201613926A (en) 2014-08-01 2015-07-31 Inhibitors of bruton's tyrosine kinase

Country Status (2)

Country Link
AR (1) AR101413A1 (en)
TW (1) TW201613926A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111454268A (en) * 2019-01-18 2020-07-28 明慧医药（上海）有限公司 Cyclic molecules as inhibitors of bruton's tyrosine kinase

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111454268A (en) * 2019-01-18 2020-07-28 明慧医药（上海）有限公司 Cyclic molecules as inhibitors of bruton's tyrosine kinase
CN111454268B (en) * 2019-01-18 2023-09-08 明慧医药（上海）有限公司 Cyclic molecules as inhibitors of bruton's tyrosine kinase

Also Published As

Publication number Publication date
AR101413A1 (en) 2016-12-14

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