MA33735B1 - Composition pharmaceutique comprenant un agoniste du glp-1 et de la methionine - Google Patents

Composition pharmaceutique comprenant un agoniste du glp-1 et de la methionine

Info

Publication number
MA33735B1
MA33735B1 MA34852A MA34852A MA33735B1 MA 33735 B1 MA33735 B1 MA 33735B1 MA 34852 A MA34852 A MA 34852A MA 34852 A MA34852 A MA 34852A MA 33735 B1 MA33735 B1 MA 33735B1
Authority
MA
Morocco
Prior art keywords
glp
agonist
methionine
pharmaceutical composition
insulin
Prior art date
Application number
MA34852A
Other languages
Arabic (ar)
English (en)
Inventor
Anette Brunner-Schwarz
Werner Müller
Verena Siefke-Henzler
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43479233&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA33735(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE102010011919A external-priority patent/DE102010011919A1/de
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of MA33735B1 publication Critical patent/MA33735B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne une composition liquide comprenant un agoniste de GLP-1 et/ou un sel pharmacologiquement tolérable de celui-ci et le cas échéant au moins un adjuvant pharmaceutiquement acceptable, caractérisé par le fait qu'elle contient de la méthionine, le cas échéant comme thérapie d'addition avec la metformine et/ou avec de l'insuline/des dérivés de l'insuline à action prolongée.
MA34852A 2009-11-13 2012-05-10 Composition pharmaceutique comprenant un agoniste du glp-1 et de la methionine MA33735B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102009052832 2009-11-13
DE102010011919A DE102010011919A1 (de) 2010-03-18 2010-03-18 Pharmazeutische Zusammensetzung umfassend einen GLP-1-Agonisten und Methionin
PCT/EP2010/067249 WO2011058082A1 (fr) 2009-11-13 2010-11-11 Composition pharmaceutique comprenant un agoniste de glp-1 et de la méthionine

Publications (1)

Publication Number Publication Date
MA33735B1 true MA33735B1 (fr) 2012-11-01

Family

ID=43479233

Family Applications (1)

Application Number Title Priority Date Filing Date
MA34852A MA33735B1 (fr) 2009-11-13 2012-05-10 Composition pharmaceutique comprenant un agoniste du glp-1 et de la methionine

Country Status (38)

Country Link
US (5) US9707176B2 (fr)
EP (2) EP2498801B1 (fr)
JP (1) JP5973918B2 (fr)
KR (3) KR101915454B1 (fr)
CN (1) CN102711804B (fr)
AR (1) AR078973A1 (fr)
AU (1) AU2010317994B2 (fr)
BR (1) BR112012011403B8 (fr)
CA (1) CA2780043C (fr)
CL (1) CL2012001233A1 (fr)
CO (1) CO6541566A2 (fr)
CR (1) CR20120242A (fr)
CY (1) CY1120270T1 (fr)
DK (1) DK2498801T3 (fr)
DO (1) DOP2012000132A (fr)
EC (1) ECSP12011889A (fr)
ES (2) ES2965209T3 (fr)
HK (1) HK1178423A1 (fr)
HR (1) HRP20180653T1 (fr)
HU (1) HUE037735T2 (fr)
IL (1) IL219722B (fr)
LT (1) LT2498801T (fr)
MA (1) MA33735B1 (fr)
MX (1) MX2012005184A (fr)
MY (1) MY159565A (fr)
NI (1) NI201200086A (fr)
NZ (1) NZ599847A (fr)
PE (1) PE20121316A1 (fr)
PL (2) PL2498801T3 (fr)
PT (2) PT2498801T (fr)
RU (1) RU2573995C2 (fr)
SG (1) SG10201500871TA (fr)
SI (1) SI2498801T1 (fr)
TN (1) TN2012000215A1 (fr)
TW (1) TWI468171B (fr)
UY (1) UY33025A (fr)
WO (1) WO2011058082A1 (fr)
ZA (1) ZA201203035B (fr)

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AU2009305472B2 (en) 2008-10-17 2013-12-19 Sanofi-Aventis Deutschland Gmbh Combination of an insulin and a GLP-1 agonist
SI2451437T1 (sl) * 2009-07-06 2017-03-31 Sanofi-Aventis Deutschlad Gmbh Vodni pripravki, ki vsebujejo metionin
EP2554183B1 (fr) * 2009-11-13 2018-04-04 Sanofi-Aventis Deutschland GmbH Composition pharmaceutique comprenant un agoniste GLP-1, de l'insuline et de la méthionine
DK2498801T3 (en) 2009-11-13 2018-05-07 Sanofi Aventis Deutschland PHARMACEUTICAL COMPOSITION INCLUDING desPro36Exendin-4 (1-39) -Lys6-NH2 AND METHIONIN
AU2011202239C1 (en) 2010-05-19 2017-03-16 Sanofi Long-acting formulations of insulins
KR101823320B1 (ko) 2010-08-30 2018-01-31 사노피-아벤티스 도이칠란트 게엠베하 제２형 진성 당뇨병 치료용 약제를 제조하기 위한 ａｖｅ００１０의 용도
RU2572703C2 (ru) * 2011-02-02 2016-01-20 Санофи-Авентис Дойчланд Гмбх Предотвращение гипогликемии у пациентов с сахарным диабетом 2 типа
CN103391798A (zh) * 2011-02-24 2013-11-13 久光制药株式会社 微针装置用glp-1类似物组合物
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
PT2750699E (pt) 2011-08-29 2015-11-03 Sanofi Aventis Deutschland Acelerómetro pendular
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
AR092862A1 (es) * 2012-07-25 2015-05-06 Hanmi Pharm Ind Co Ltd Formulacion liquida de insulina de accion prolongada y un peptido insulinotropico y metodo de preparacion
UA116217C2 (uk) 2012-10-09 2018-02-26 Санофі Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
EP2934568B1 (fr) 2012-12-21 2017-10-18 Sanofi Dérivés de exendin-4 en tant que glp1/gip double ou agonistes trigonaux de glp1/gip/glucagon
CN103893744B (zh) * 2012-12-24 2017-12-19 杭州九源基因工程有限公司 一种治疗糖尿病的药物制剂及其制备方法
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JP6457484B2 (ja) 2013-04-03 2019-01-23 サノフイＳａｎｏｆｉ インスリンの長時間作用型製剤による糖尿病の治療
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TW201609795A (zh) 2013-12-13 2016-03-16 賽諾菲公司 作為雙重ｇｌｐ－１／ｇｉｐ受體促效劑的艾塞那肽－４（ｅｘｅｎｄｉｎ－４）胜肽類似物
WO2015086733A1 (fr) 2013-12-13 2015-06-18 Sanofi Agonistes mixtes des récepteurs du glp-1/glucagon
BR112016015851A2 (pt) 2014-01-09 2017-08-08 Sanofi Sa Formulações farmacêuticas estabilizadas de insulina aspart
CA2932877A1 (fr) 2014-01-09 2015-07-16 Sanofi Formulations pharmaceutiques stabilisees d'analogues de l'insuline et/ou de derives de l'insuline
WO2015104311A1 (fr) 2014-01-09 2015-07-16 Sanofi Formulations pharmaceutiques stabilisées sans glycérol d'analogues de l'insuline et/ou de dérivés de l'insuline
TW201625669A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑
TW201625670A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑
TW201625668A (zh) 2014-04-07 2016-07-16 賽諾菲公司 作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物
US9932381B2 (en) 2014-06-18 2018-04-03 Sanofi Exendin-4 derivatives as selective glucagon receptor agonists
KR102578030B1 (ko) 2014-12-12 2023-09-14 사노피-아벤티스 도이칠란트 게엠베하 인슐린 글라진／릭시세나티드 고정비 제형
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
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AR105319A1 (es) 2015-06-05 2017-09-27 Sanofi Sa Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico
AR105284A1 (es) 2015-07-10 2017-09-20 Sanofi Sa Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón
EP3922269A1 (fr) * 2016-03-16 2021-12-15 Prolynx LLC Conjugués à libération prolongée d'analogues d'exénatide
TW201821434A (zh) 2016-10-10 2018-06-16 法商賽諾菲公司 製備包含親脂性修飾的離胺酸側鏈的肽的方法
JP2019535835A (ja) * 2016-11-22 2019-12-12 バイオコン リサーチ リミテッドＢｉｏｃｏｎ Ｒｅｓｅａｒｃｈ Ｌｉｍｉｔｅｄ Ｇｌｐ−１類似体の医薬組成物
AR110299A1 (es) 2016-12-02 2019-03-13 Sanofi Sa Conjugados que comprenden un agonista dual de glp-1 / glucagón, un conector y ácido hialurónico
WO2019122109A1 (fr) * 2017-12-21 2019-06-27 Sanofi Composition pharmaceutique liquide
TWI829687B (zh) 2018-05-07 2024-01-21 丹麥商諾佛 儂迪克股份有限公司 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物
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UY33025A (es) 2011-06-30
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SI2498801T1 (en) 2018-06-29
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AU2010317994B2 (en) 2014-03-06
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