DK134189D0 - Insulinforbindelser - Google Patents

Insulinforbindelser

Info

Publication number
DK134189D0
DK134189D0 DK134189A DK134189A DK134189D0 DK 134189 D0 DK134189 D0 DK 134189D0 DK 134189 A DK134189 A DK 134189A DK 134189 A DK134189 A DK 134189A DK 134189 D0 DK134189 D0 DK 134189D0
Authority
DK
Denmark
Prior art keywords
image
insulin compounds
coded
amino acid
acid residue
Prior art date
Application number
DK134189A
Other languages
English (en)
Inventor
Per Balschmidt
Finn Benned Hansen
Original Assignee
Nordisk Gentofte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordisk Gentofte filed Critical Nordisk Gentofte
Priority to DK134189A priority Critical patent/DK134189D0/da
Publication of DK134189D0 publication Critical patent/DK134189D0/da
Priority to HU902706A priority patent/HUT58349A/hu
Priority to DE69015811T priority patent/DE69015811T2/de
Priority to ES90905190T priority patent/ES2068384T3/es
Priority to AT90905190T priority patent/ATE116661T1/de
Priority to EP90905190A priority patent/EP0463072B1/en
Priority to KR1019910701125A priority patent/KR920701250A/ko
Priority to AU53448/90A priority patent/AU637365B2/en
Priority to JP2505142A priority patent/JPH04503808A/ja
Priority to PCT/DK1990/000071 priority patent/WO1990011299A1/en
Priority to DK90905190.6T priority patent/DK0463072T3/da
Priority to CA002049961A priority patent/CA2049961A1/en
Priority to NZ232953A priority patent/NZ232953A/en
Priority to DD90338860A priority patent/DD298788A5/de
Priority to CN90101564A priority patent/CN1045793A/zh
Priority to YU53290A priority patent/YU53290A/sh
Priority to US07/495,798 priority patent/US5430016A/en
Priority to ZA902086A priority patent/ZA902086B/xx
Priority to PT93502A priority patent/PT93502B/pt
Priority to IL93792A priority patent/IL93792A0/xx
Priority to IE100490A priority patent/IE66564B1/en
Priority to GR900100206A priority patent/GR1002545B/el
Priority to NO913687A priority patent/NO300640B1/no
Priority to FI914419A priority patent/FI914419A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK134189A 1989-03-20 1989-03-20 Insulinforbindelser DK134189D0 (da)

Priority Applications (24)

Application Number Priority Date Filing Date Title
DK134189A DK134189D0 (da) 1989-03-20 1989-03-20 Insulinforbindelser
DE69015811T DE69015811T2 (de) 1989-03-20 1990-03-15 Insulinverbindungen.
DK90905190.6T DK0463072T3 (da) 1989-03-20 1990-03-15 Hidtil ukendte insulinforbindelser
CA002049961A CA2049961A1 (en) 1989-03-20 1990-03-15 Insulin compounds
ES90905190T ES2068384T3 (es) 1989-03-20 1990-03-15 Nuevos compuestos de insulina.
AT90905190T ATE116661T1 (de) 1989-03-20 1990-03-15 Insulinverbindungen.
EP90905190A EP0463072B1 (en) 1989-03-20 1990-03-15 Novel insulin compounds
KR1019910701125A KR920701250A (ko) 1989-03-20 1990-03-15 신규 인슐린 화합물
AU53448/90A AU637365B2 (en) 1989-03-20 1990-03-15 Novel insulin compounds
JP2505142A JPH04503808A (ja) 1989-03-20 1990-03-15 新規インシュリン化合物
PCT/DK1990/000071 WO1990011299A1 (en) 1989-03-20 1990-03-15 Novel insulin compounds
HU902706A HUT58349A (en) 1989-03-20 1990-03-15 Process for producing new isoleucine derivatives
NZ232953A NZ232953A (en) 1989-03-20 1990-03-16 Arg ao -insulin derivatives and pharmaceutical compositions
DD90338860A DD298788A5 (de) 1989-03-20 1990-03-19 Neue insulinverbindungen
IL93792A IL93792A0 (en) 1989-03-20 1990-03-19 Insulin compounds,their preparation and compositions comprising them
CN90101564A CN1045793A (zh) 1989-03-20 1990-03-19 新的胰岛素化合物及其制备方法
YU53290A YU53290A (sh) 1989-03-20 1990-03-19 Postupak za dobijanje novih jedinjenja insulina
US07/495,798 US5430016A (en) 1989-03-20 1990-03-19 Insulin compounds and compositions
ZA902086A ZA902086B (en) 1989-03-20 1990-03-19 Novel insulin compounds
PT93502A PT93502B (pt) 1989-03-20 1990-03-19 Processo para a preparacao de novos derivados de insulina e de composicoes farmaceuticas que os contem
IE100490A IE66564B1 (en) 1989-03-20 1990-03-20 Novel insulin compounds
GR900100206A GR1002545B (el) 1989-03-20 1990-03-20 Μεθοδος παρασκευης νεων συνθεσεων ινσουλινης.
NO913687A NO300640B1 (no) 1989-03-20 1991-09-19 Fremgangsmåte ved fremstilling av nye insulinforbindelser
FI914419A FI914419A0 (fi) 1989-03-20 1991-09-19 Nya insulinfoereningar.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK134189A DK134189D0 (da) 1989-03-20 1989-03-20 Insulinforbindelser

Publications (1)

Publication Number Publication Date
DK134189D0 true DK134189D0 (da) 1989-03-20

Family

ID=8103787

Family Applications (2)

Application Number Title Priority Date Filing Date
DK134189A DK134189D0 (da) 1989-03-20 1989-03-20 Insulinforbindelser
DK90905190.6T DK0463072T3 (da) 1989-03-20 1990-03-15 Hidtil ukendte insulinforbindelser

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK90905190.6T DK0463072T3 (da) 1989-03-20 1990-03-15 Hidtil ukendte insulinforbindelser

Country Status (23)

Country Link
US (1) US5430016A (da)
EP (1) EP0463072B1 (da)
JP (1) JPH04503808A (da)
KR (1) KR920701250A (da)
CN (1) CN1045793A (da)
AT (1) ATE116661T1 (da)
AU (1) AU637365B2 (da)
CA (1) CA2049961A1 (da)
DD (1) DD298788A5 (da)
DE (1) DE69015811T2 (da)
DK (2) DK134189D0 (da)
ES (1) ES2068384T3 (da)
FI (1) FI914419A0 (da)
GR (1) GR1002545B (da)
HU (1) HUT58349A (da)
IE (1) IE66564B1 (da)
IL (1) IL93792A0 (da)
NO (1) NO300640B1 (da)
NZ (1) NZ232953A (da)
PT (1) PT93502B (da)
WO (1) WO1990011299A1 (da)
YU (1) YU53290A (da)
ZA (1) ZA902086B (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
US5304473A (en) * 1991-06-11 1994-04-19 Eli Lilly And Company A-C-B proinsulin, method of manufacturing and using same, and intermediates in insulin production
NZ245170A (en) * 1991-11-26 1994-07-26 Lilly Co Eli Insulin and proinsulin analogues with arg at b31, b32 and ao and pharmaceutical compositions
US5948751A (en) * 1996-06-20 1999-09-07 Novo Nordisk A/S X14-mannitol
AU1111799A (en) 1997-10-24 1999-05-17 Eli Lilly And Company Fatty acid-acylated insulin analogs
US6531448B1 (en) 1997-12-23 2003-03-11 Eli Lilly And Company Insoluble compositions for controlling blood glucose
US7378390B2 (en) * 1999-12-29 2008-05-27 Novo Nordisk A/S Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast
BR0215029A (pt) * 2001-12-20 2005-12-20 Lilly Co Eli Molécula de insulina, uso da mesma, composição, uso desta, microcristal, processo para prepará-lo, uso deste, e, métodos para preparar uma molécula de insulina, para tratar hiperglicemia, e para tratar diabetes mellitus
AU2004234345A1 (en) * 2003-04-29 2004-11-11 Eli Lilly And Company Insulin analogs having protracted time action
EP2131723B1 (en) * 2007-03-19 2013-07-24 Insuline Medical Ltd. Device for substance measurement
EP2131900B1 (en) * 2007-03-19 2018-05-30 Insuline Medical Ltd. Drug delivery device
WO2009081262A1 (en) 2007-12-18 2009-07-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
US9220837B2 (en) 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
JP5695909B2 (ja) 2008-01-09 2015-04-08 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 極度に遅延した時間作用プロファイルを有する新規なインスリン誘導体
BRPI0907371A2 (pt) 2008-01-09 2015-11-24 Sanofi Aventis Deutschland derivados de insulina com um perfil de tempo-ação muito retardado
HUE037449T2 (hu) 2008-10-17 2018-08-28 Sanofi Aventis Deutschland Egy inzulin és egy GLP-1 agonista kombinációja
WO2010052579A2 (en) 2008-11-07 2010-05-14 Insuline Medical Ltd. Device and method for drug delivery
RU2537239C2 (ru) 2009-11-13 2014-12-27 Санофи-Авентис Дойчланд Гмбх Фармацевтическая композиция, включающая агонист glp-1, инсулин и метионин
PE20121316A1 (es) 2009-11-13 2012-10-05 Sanofi Aventis Deutschland Composicion farmaceutica que comprende un agonista de glp-1 y metionina
PT2611458T (pt) 2010-08-30 2016-12-16 Sanofi Aventis Deutschland Utilização de ave0010 para o fabrico de um medicamento para o tratamento da diabetes mellitus tipo 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
PT2750699E (pt) 2011-08-29 2015-11-03 Sanofi Aventis Deutschland Acelerómetro pendular
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
TW201534616A (zh) 2013-05-02 2015-09-16 Glaxosmithkline Ip Dev Ltd 治療性胜肽
CA2970200A1 (en) 2014-12-12 2016-06-16 Sanofi-Aventis Deutschland Gmbh Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
CN106323840A (zh) * 2016-09-13 2017-01-11 西南石油大学 一种页岩孔隙度测量方法
CN109735589B (zh) * 2019-01-02 2020-07-10 珠海冀百康生物科技有限公司 一种胰岛素DesB30的制备方法
CN113773398B (zh) * 2020-06-10 2023-05-23 宁波鲲鹏生物科技有限公司 一种德谷胰岛素衍生物及其应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
IE50892B1 (en) * 1980-02-11 1986-08-06 Novo Industri As Process for preparing insulin esters
DE3326473A1 (de) * 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DK58285D0 (da) * 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
US4946828A (en) * 1985-03-12 1990-08-07 Novo Nordisk A/S Novel insulin peptides
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
US5008241A (en) * 1985-03-12 1991-04-16 Novo Nordisk A/S Novel insulin peptides
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat
DK129385A (da) * 1985-03-22 1986-09-23 Novo Industri As Peptider og fremstilling deraf
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
DE3717370A1 (de) * 1987-05-22 1988-12-01 Hoechst Ag Mischkristalle aus insulin und insulinderivaten, verfahren zur herstellung dieser mischkristalle, diese mischkristalle enthaltende pharmazeutische mittel und ihre verwendung zur behandlung von diabetes mellitus
DK336188D0 (da) * 1988-06-20 1988-06-20 Nordisk Gentofte Propeptider
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung

Also Published As

Publication number Publication date
FI914419A0 (fi) 1991-09-19
WO1990011299A1 (en) 1990-10-04
DE69015811D1 (de) 1995-02-16
NO913687L (no) 1991-11-19
JPH04503808A (ja) 1992-07-09
ZA902086B (en) 1990-11-28
DE69015811T2 (de) 1995-05-11
GR900100206A (el) 1991-07-31
ATE116661T1 (de) 1995-01-15
CA2049961A1 (en) 1990-09-21
IE901004L (en) 1990-09-20
AU637365B2 (en) 1993-05-27
US5430016A (en) 1995-07-04
HU902706D0 (en) 1991-12-30
CN1045793A (zh) 1990-10-03
DD298788A5 (de) 1992-03-12
NZ232953A (en) 1992-10-28
NO913687D0 (no) 1991-09-19
EP0463072A1 (en) 1992-01-02
KR920701250A (ko) 1992-08-11
IE66564B1 (en) 1996-01-24
PT93502B (pt) 1996-02-29
EP0463072B1 (en) 1995-01-04
NO300640B1 (no) 1997-06-30
YU53290A (sh) 1992-12-21
IL93792A0 (en) 1990-12-23
AU5344890A (en) 1990-10-22
PT93502A (pt) 1990-11-07
HUT58349A (en) 1992-02-28
ES2068384T3 (es) 1995-04-16
DK0463072T3 (da) 1995-06-12
GR1002545B (el) 1997-01-28

Similar Documents

Publication Publication Date Title
DE69015811T2 (de) Insulinverbindungen.
AU4799793A (en) Beta -aminoalkyl and beta -n-peptidylaminoalkyl boronic acids
DK0585285T3 (da) Stabiliserede enzymer
ATE90107T1 (de) Peptide mit collagenase hemmender wirkung.
AU6954887A (en) Oligopeptidyl nitrile derivatives, agents containing them, a process for their preparation, and their use
ES8501364A1 (es) Un metodo para la preparacion de nuevos polipeptidos.
HU9401584D0 (en) Preparation of substituted piperidines
NO971621L (no) Keratinocyttvekstfaktoranaloger
ES8407011A1 (es) Un procedimiento para la preparacion de un derivado de un peptido ciclico a-21978c.
DE69814837D1 (de) Verfahren zur Herstellung von Heteroaryl-Zink-Halogeniden
MX173831B (es) Compuestos de naftil-azo-pirazolona y procedimiento para la preparacion de los mismos
DK0661263T3 (da) Fremgangsmåde til fremstilling af 2,4,5-tribrompyrrol-3-carbonitril
ES481287A1 (es) Un procedimiento para la preparacion de derivados de 1,2- dimetilbiciclo-3.2.1-octano.
AR241084A2 (es) Compuestos derivados de piridazina, formulacion y composicion fungicida que los comprende y procedimiento para prepararlos".
DE69608260T2 (de) Wässrige spectinomycinborat-auflösung
IL109978A0 (en) Ureins derived from alpha,omega-diamino acids and their preparation
EP0506971A4 (en) Peptide with activity of inhibiting phospholipase a2 originating in inflamed part
JPS5283829A (en) Cyclic compound
KR840005082A (ko) 노나펩타이드의 제조방법
EP0684253A4 (en) DESALANINE LEVEL ANOMICIN A DERIVATIVES AND PRODUCTION THEREOF.
ES8702900A1 (es) Procedimiento de obtencion de un compuesto de guanidiltia- zol, util como inhibidor de secrecion gastrica

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment
PUP Patent expired