GB2160201B
(en)
|
1984-06-14 |
1988-05-11 |
Wyeth John & Brother Ltd |
Quinazoline and cinnoline derivatives
|
US5123951A
(en)
|
1986-03-31 |
1992-06-23 |
Rhone-Poulenc Nederland B.V. |
Synergistic plant growth regulator compositions
|
JPS646261A
(en)
|
1987-03-31 |
1989-01-10 |
Nisshin Flour Milling Co |
4-thioquinazoline derivative, its production and antiulcer agent containing said derivative as active component
|
US5143854A
(en)
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
US5034393A
(en)
|
1989-07-27 |
1991-07-23 |
Dowelanco |
Fungicidal use of pyridopyrimidine, pteridine, pyrimidopyrimidine, pyrimidopyridazine, and pyrimido-1,2,4-triazine derivatives
|
US5238951A
(en)
|
1991-02-01 |
1993-08-24 |
E. R. Squibb & Sons, Inc. |
Heterocyclic amido prostaglandin analogs
|
DE4114733A1
(de)
|
1991-05-06 |
1992-11-12 |
Huels Chemische Werke Ag |
Verfahren zur herstellung von substituierten malonesteraniliden und malonsaeure-monoaniliden
|
US5710158A
(en)
|
1991-05-10 |
1998-01-20 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
|
US5480883A
(en)
|
1991-05-10 |
1996-01-02 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
|
US6057344A
(en)
|
1991-11-26 |
2000-05-02 |
Sepracor, Inc. |
Methods for treating hypertension, and angina using optically pure (-) amlodipine
|
US6498144B1
(en)
|
1993-10-18 |
2002-12-24 |
North Shore - Long Island Jewish Research Institute |
Use of scatter factor to enhance angiogenesis
|
IL112249A
(en)
|
1994-01-25 |
2001-11-25 |
Warner Lambert Co |
Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
|
GB9510757D0
(en)
|
1994-09-19 |
1995-07-19 |
Wellcome Found |
Therapeuticaly active compounds
|
TW321649B
(ja)
|
1994-11-12 |
1997-12-01 |
Zeneca Ltd |
|
GB9508538D0
(en)
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
US5747498A
(en)
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
ES2203642T3
(es)
|
1995-06-07 |
2004-04-16 |
Pfizer Inc. |
Derivados de pirimidina heterociclicos con anillos condensados.
|
EP0832073B1
(en)
|
1995-06-07 |
2002-01-16 |
Sugen, Inc. |
Quinazolines and pharmaceutical compositions
|
US5650415A
(en)
|
1995-06-07 |
1997-07-22 |
Sugen, Inc. |
Quinoline compounds
|
GB9514265D0
(en)
|
1995-07-13 |
1995-09-13 |
Wellcome Found |
Hetrocyclic compounds
|
JP4009681B2
(ja)
|
1995-11-07 |
2007-11-21 |
キリンファーマ株式会社 |
血小板由来成長因子受容体自己リン酸化を阻害するキノリン誘導体ならびにキナゾリン誘導体およびそれらを含有する薬学的組成物
|
GB9523675D0
(en)
|
1995-11-20 |
1996-01-24 |
Celltech Therapeutics Ltd |
Chemical compounds
|
GB9624482D0
(en)
|
1995-12-18 |
1997-01-15 |
Zeneca Phaema S A |
Chemical compounds
|
NZ325248A
(en)
|
1995-12-23 |
1999-09-29 |
Pfizer Res & Dev |
Quinoline and quinazoline compounds useful in therapy
|
SI0880508T1
(en)
|
1996-02-13 |
2003-10-31 |
Astrazeneca Ab |
Quinazoline derivatives as vegf inhibitors
|
GB9603095D0
(en)
|
1996-02-14 |
1996-04-10 |
Zeneca Ltd |
Quinazoline derivatives
|
ES2169355T3
(es)
|
1996-03-05 |
2002-07-01 |
Astrazeneca Ab |
Derivados de 4-anilinoquinazolina.
|
JP2000506880A
(ja)
|
1996-03-15 |
2000-06-06 |
ゼネカ・リミテッド |
シンノリン誘導体及びその使用
|
US6107300A
(en)
|
1996-03-27 |
2000-08-22 |
Dupont Pharmaceuticals |
Arylamino fused pyrimidines
|
CA2249446C
(en)
|
1996-04-12 |
2008-06-17 |
Warner-Lambert Company |
Irreversible inhibitors of tyrosine kinases
|
HRP970371A2
(en)
|
1996-07-13 |
1998-08-31 |
Kathryn Jane Smith |
Heterocyclic compounds
|
JP4386967B2
(ja)
|
1996-07-13 |
2009-12-16 |
グラクソ、グループ、リミテッド |
プロテインチロシンキナーゼ阻害剤としての縮合複素環式化合物
|
US5962407A
(en)
|
1996-07-26 |
1999-10-05 |
Kelly; Michael T. |
Loloatin derivatives and analogs
|
GB9718972D0
(en)
|
1996-09-25 |
1997-11-12 |
Zeneca Ltd |
Chemical compounds
|
DE69733825T2
(de)
|
1996-09-25 |
2006-06-08 |
Astrazeneca Ab |
Chinolin-derivate die den effekt von wachstumsfaktoren wie vegf vezögern
|
ATE480521T1
(de)
|
1996-10-01 |
2010-09-15 |
Kyowa Hakko Kirin Co Ltd |
Stickstoff enthaltende heterocyclische verbindungen
|
GB9700504D0
(en)
|
1997-01-11 |
1997-02-26 |
Pfizer Ltd |
Pharmaceutical compounds
|
GB9705361D0
(en)
|
1997-03-14 |
1997-04-30 |
Celltech Therapeutics Ltd |
Chemical compounds
|
UA73073C2
(uk)
|
1997-04-03 |
2005-06-15 |
Уайт Холдінгз Корпорейшн |
Заміщені 3-ціанохіноліни, спосіб їх одержання та фармацевтична композиція
|
DE69816080T2
(de)
|
1997-04-18 |
2004-04-15 |
Kirin Beer K.K. |
Verfahren zur herstellung von chinolinderivaten
|
PT977737E
(pt)
|
1997-04-22 |
2004-02-27 |
Janssen Pharmaceutica Nv |
Quino- e quinazolinas antagonistas de crf
|
GB9708917D0
(en)
|
1997-05-01 |
1997-06-25 |
Pfizer Ltd |
Compounds useful in therapy
|
AR012634A1
(es)
|
1997-05-02 |
2000-11-08 |
Sugen Inc |
Compuesto basado en quinazolina, composicion famaceutica que lo comprende, metodo para sintetizarlo, su uso, metodos de modulacion de la funcion deserina/treonina proteinaquinasa con dicho compuesto y metodo in vitro para identificar compuestos que modulan dicha funcion
|
ZA986732B
(en)
|
1997-07-29 |
1999-02-02 |
Warner Lambert Co |
Irreversible inhibitiors of tyrosine kinases
|
ES2289791T3
(es)
|
1997-08-22 |
2008-02-01 |
Astrazeneca Ab |
Derivados de oxindolilquinazolina como inhibidores de la angiogenesis.
|
RS49779B
(sr)
|
1998-01-12 |
2008-06-05 |
Glaxo Group Limited, |
Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
|
WO1999061428A1
(en)
|
1998-05-28 |
1999-12-02 |
Parker Hughes Institute |
Quinazolines for treating brain tumor
|
JP4516690B2
(ja)
|
1998-08-11 |
2010-08-04 |
ノバルティス アーゲー |
血管形成阻害活性を有するイソキノリン誘導体
|
KR20010089171A
(ko)
|
1998-08-21 |
2001-09-29 |
추후제출 |
퀴나졸린 유도체
|
US6184226B1
(en)
|
1998-08-28 |
2001-02-06 |
Scios Inc. |
Quinazoline derivatives as inhibitors of P-38 α
|
WO2000015202A2
(de)
|
1998-09-10 |
2000-03-23 |
Ipr-Institute For Pharmaceutical Research Ag |
Topisch anwendbare mittel
|
AU763669B2
(en)
|
1998-09-29 |
2003-07-31 |
Wyeth Holdings Corporation |
Substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors
|
US6288082B1
(en)
|
1998-09-29 |
2001-09-11 |
American Cyanamid Company |
Substituted 3-cyanoquinolines
|
JP2002526538A
(ja)
|
1998-10-01 |
2002-08-20 |
アストラゼネカ アクチボラグ |
化学化合物
|
FR2784030B1
(fr)
|
1998-10-02 |
2002-12-20 |
Inst Nat Sante Rech Med |
Utilisation de bloqueurs des canaux calciques et/ou cgmp-dependants pour le traitement de pathologies de la retine
|
ATE294796T1
(de)
|
1998-10-08 |
2005-05-15 |
Astrazeneca Ab |
Chinazolin derivate
|
US6344455B1
(en)
|
1998-11-19 |
2002-02-05 |
Warner-Lambert Company |
N-[4-(3-chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide, and irreversible inhibitor of tyrosine kinases
|
CA2361057C
(en)
|
1999-01-22 |
2010-04-06 |
Kazuo Kubo |
Quinoline derivatives and quinazoline derivatives
|
CA2674803C
(en)
|
1999-02-10 |
2012-10-09 |
Astrazeneca Ab |
Quinazoline derivatives as angiogenesis inhibitors
|
GB9904103D0
(en)
|
1999-02-24 |
1999-04-14 |
Zeneca Ltd |
Quinoline derivatives
|
US6080747A
(en)
|
1999-03-05 |
2000-06-27 |
Hughes Institute |
JAK-3 inhibitors for treating allergic disorders
|
DE19911509A1
(de)
|
1999-03-15 |
2000-09-21 |
Boehringer Ingelheim Pharma |
Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
|
JP2002539262A
(ja)
|
1999-03-19 |
2002-11-19 |
パーカー ヒューズ インスティテュート |
キナゾリン化合物製剤および治療におけるその使用
|
US6258820B1
(en)
|
1999-03-19 |
2001-07-10 |
Parker Hughes Institute |
Synthesis and anti-tumor activity of 6,7-dialkoxy-4-phenylamino-quinazolines
|
RS49836B
(sr)
|
1999-03-31 |
2008-08-07 |
Pfizer Products Inc., |
Postupci i intermedijeri za dobijanje anti-kancernih jedinjenja
|
WO2000057868A2
(en)
|
1999-03-31 |
2000-10-05 |
The Procter & Gamble Company |
Use of carbamamic acid derivatives for the treatment of viral infections
|
GB9910577D0
(en)
|
1999-05-08 |
1999-07-07 |
Zeneca Ltd |
Chemical compounds
|
GB9910580D0
(en)
|
1999-05-08 |
1999-07-07 |
Zeneca Ltd |
Chemical compounds
|
US6126917A
(en)
|
1999-06-01 |
2000-10-03 |
Hadasit Medical Research Services And Development Ltd. |
Epidermal growth factor receptor binding compounds for positron emission tomography
|
PT1731511E
(pt)
|
1999-06-21 |
2015-11-13 |
Boehringer Ingelheim Pharma |
Heterociclos bicíclicos, medicamentos contendo estes compostos, a sua utilização e processos para a sua preparação
|
GB9922171D0
(en)
|
1999-09-21 |
1999-11-17 |
Zeneca Ltd |
Chemical compounds
|
CA2384291A1
(en)
*
|
1999-09-21 |
2001-03-29 |
Astrazeneca Ab |
Quinazoline derivatives and their use as pharmaceuticals
|
US6759410B1
(en)
|
1999-11-23 |
2004-07-06 |
Smithline Beecham Corporation |
3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors
|
CA2392554A1
(en)
|
1999-11-30 |
2001-06-28 |
Parker Hughes Institute |
Inhibitors of thrombin induced platelet aggregation
|
US20020002169A1
(en)
|
1999-12-08 |
2002-01-03 |
Griffin John H. |
Protein kinase inhibitors
|
AU2223201A
(en)
|
1999-12-24 |
2001-07-09 |
Kirin Beer Kabushiki Kaisha |
Quinoline and quinazoline derivatives and drugs containing the same
|
US6525046B1
(en)
|
2000-01-18 |
2003-02-25 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Aromatic heterocyclic compounds as antiinflammatory agents
|
US6977259B2
(en)
|
2000-01-28 |
2005-12-20 |
Astrazeneca Ab |
Quinoline derivatives and their use as aurora 2 kinase inhibitors
|
US6664390B2
(en)
|
2000-02-02 |
2003-12-16 |
Warner-Lambert Company Llc |
Method for the simplified production of (3-chloro-4-fluorophenyl)-[7-(3-morpholin-4-yl-propoxy)-6-nitro-quinazoline-4-yl]-amine or (3-chloro-4-fluorophenyl)-[7-(3-morpholin-4-yl-propoxy)-6-amino-quinazoline-4-yl]-amine
|
CA2398754A1
(en)
|
2000-02-07 |
2001-08-09 |
Abbott Gmbh & Co. Kg |
2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors
|
BRPI0108394B8
(pt)
|
2000-02-15 |
2021-05-25 |
Upjohn Co |
inibidores de proteína de quinase de 2-indolinona de pirrol substituído, seus sais e composições farmacêuticas compreendendo os mesmos
|
CN1190197C
(zh)
|
2000-03-13 |
2005-02-23 |
惠氏控股公司 |
氰基喹啉用于制备治疗或抑制结肠息肉药物中的用途
|
US6521618B2
(en)
|
2000-03-28 |
2003-02-18 |
Wyeth |
3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
|
US6608048B2
(en)
|
2000-03-28 |
2003-08-19 |
Wyeth Holdings |
Tricyclic protein kinase inhibitors
|
US6627634B2
(en)
|
2000-04-08 |
2003-09-30 |
Boehringer Ingelheim Pharma Kg |
Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them
|
UA73993C2
(uk)
|
2000-06-06 |
2005-10-17 |
Астразенека Аб |
Хіназолінові похідні для лікування пухлин та фармацевтична композиція
|
CA2413424C
(en)
|
2000-06-22 |
2007-10-02 |
Pfizer Products Inc. |
Substituted bicyclic derivatives for the treatment of abnormal cell growth
|
EP1174118A1
(de)
|
2000-06-28 |
2002-01-23 |
Cognis France S.A. |
Verwendung von Inulinen und Inulinderivaten
|
RU2283311C2
(ru)
|
2000-06-28 |
2006-09-10 |
Астразенека Аб |
Замещенные производные хиназолина и их применение в качестве ингибиторов
|
FR2811658B1
(fr)
|
2000-07-17 |
2004-07-02 |
Cfpi Nufarm |
Reacteur biologique a lit fixe immerge et procede de traitement d'effluents liquides
|
JP2002030083A
(ja)
*
|
2000-07-18 |
2002-01-29 |
Kirin Brewery Co Ltd |
N−(2−クロロ−4−{[6−メトキシ−7−(3−ピリジルメトキシ)−4−キノリル]オキシ}フェニル)−n’−プロピルウレアの二塩酸塩
|
US7427689B2
(en)
|
2000-07-28 |
2008-09-23 |
Georgetown University |
ErbB-2 selective small molecule kinase inhibitors
|
US7115615B2
(en)
|
2000-08-21 |
2006-10-03 |
Astrazeneca |
Quinazoline derivatives
|
FR2813307B1
(fr)
|
2000-08-23 |
2002-11-08 |
Sanofi Synthelabo |
Aminoalkenylbenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant
|
US6740651B2
(en)
|
2000-08-26 |
2004-05-25 |
Boehringer Ingelheim Pharma Kg |
Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases
|
DE10042058A1
(de)
|
2000-08-26 |
2002-03-07 |
Boehringer Ingelheim Pharma |
Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
|
US6653305B2
(en)
|
2000-08-26 |
2003-11-25 |
Boehringer Ingelheim Pharma Kg |
Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them
|
US6403580B1
(en)
|
2000-08-26 |
2002-06-11 |
Boehringer Ingelheim Pharma Kg |
Quinazolines, pharmaceutical compositions containing these compounds, their use and processes for preparing them
|
US6617329B2
(en)
|
2000-08-26 |
2003-09-09 |
Boehringer Ingelheim Pharma Kg |
Aminoquinazolines and their use as medicaments
|
US6656946B2
(en)
|
2000-08-26 |
2003-12-02 |
Boehringer Ingelheim Pharma Kg |
Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases
|
US6939866B2
(en)
|
2000-10-13 |
2005-09-06 |
Astrazeneca Ab |
Quinazoline derivatives
|
AU2001292138A1
(en)
|
2000-10-13 |
2002-04-22 |
Astrazeneca Ab |
Quinazoline derivatives with anti-tumour activity
|
MX242553B
(es)
|
2000-10-20 |
2006-12-06 |
Eisai Co Ltd |
Derivados aromaticos que contienen nitrogeno.
|
JP2004512335A
(ja)
|
2000-10-25 |
2004-04-22 |
アストラゼネカ アクチボラグ |
キナゾリン誘導体
|
US7253184B2
(en)
|
2000-11-02 |
2007-08-07 |
Astrazeneca Ab |
4-Substituted quinolines as antitumor agents
|
WO2002036577A1
(fr)
|
2000-11-02 |
2002-05-10 |
Nippon Shinyaku Co., Ltd. |
Derives quinazoline et medicaments
|
JP2004514718A
(ja)
|
2000-11-02 |
2004-05-20 |
アストラゼネカ アクチボラグ |
抗癌剤としての置換キノリン類
|
US7019012B2
(en)
|
2000-12-20 |
2006-03-28 |
Boehringer Ingelheim International Pharma Gmbh & Co. Kg |
Quinazoline derivatives and pharmaceutical compositions containing them
|
US6900220B2
(en)
|
2001-01-02 |
2005-05-31 |
Syntex (U.S.A.) Llc |
Quinazolone derivatives as alpha 1A/B adrenergic receptor antagonists
|
GB0103046D0
(en)
|
2001-02-07 |
2001-03-21 |
Novartis Ag |
Organic Compounds
|
JP2002265365A
(ja)
|
2001-03-08 |
2002-09-18 |
Koyo Chemical Kk |
好中球機能抑制剤
|
WO2002085895A1
(en)
|
2001-04-19 |
2002-10-31 |
Astrazeneca Ab |
Quinazoline derivatives
|
MXPA03009662A
(es)
|
2001-04-27 |
2004-12-06 |
Kirin Brewery |
Derivados de quinolina y derivados de quinazolina que tienen grupos azolilo.
|
SE0101675D0
(sv)
|
2001-05-11 |
2001-05-11 |
Astrazeneca Ab |
Novel composition
|
WO2002092577A1
(en)
|
2001-05-14 |
2002-11-21 |
Astrazeneca Ab |
Quinazoline derivatives
|
WO2002092578A1
(en)
|
2001-05-14 |
2002-11-21 |
Astrazeneca Ab |
Quinazoline derivatives
|
WO2002092579A1
(en)
|
2001-05-14 |
2002-11-21 |
Astrazeneca Ab |
4-anilinoquinazoline derivatives
|
US6734303B2
(en)
|
2001-05-18 |
2004-05-11 |
Pfizer Inc. |
Process for the production of quinazolines
|
DE10125432A1
(de)
|
2001-05-25 |
2002-11-28 |
Bayer Ag |
Substituierte Benzoylketone
|
AU2002350105A1
(en)
|
2001-06-21 |
2003-01-08 |
Ariad Pharmaceuticals, Inc. |
Novel quinazolines and uses thereof
|
CN100415720C
(zh)
|
2001-06-22 |
2008-09-03 |
麒麟医药株式会社 |
喹啉衍生物和喹唑啉衍生物以及含有这些化合物的药物组合物
|
KR100397792B1
(ko)
|
2001-06-28 |
2003-09-13 |
한국과학기술연구원 |
4-(페닐아미노)-[1,4]디옥사노[2,3-g]퀴나졸린 유도체 및그의 제조방법
|
GB0118752D0
(en)
|
2001-08-01 |
2001-09-26 |
Pfizer Ltd |
Process for the production of quinazolines
|
US7229774B2
(en)
|
2001-08-02 |
2007-06-12 |
Regents Of The University Of Michigan |
Expression profile of prostate cancer
|
DK3168218T3
(en)
|
2001-08-15 |
2019-01-14 |
Pharmacia & Upjohn Co Llc |
Crystalline comprising an L-malic acid salt of N- [2- (DIETHYLAMINO) ETHYL] -5 - [(5-FLUOR-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDE) METHYL] -2,4 -DIMETHYL-1H-PYRROL-3-CARBOXAMIDE FOR USE AS A MEDICINE
|
US20030066060A1
(en)
|
2001-09-28 |
2003-04-03 |
Ford Richard L. |
Cross profile guided optimization of program execution
|
EP1447405A4
(en)
|
2001-10-17 |
2005-01-12 |
Kirin Brewery |
QUINOLINE OR QUINAZOLINE DERIVATIVES INHIBITING THE AUTOPHOSPHORYLATION OF FIBROBLAST GROWTH FACTOR RECEPTORS
|
AU2002361577A1
(en)
|
2001-10-30 |
2003-05-12 |
Merck And Co., Inc. |
Tyrosine kinase inhibitors
|
GB0126433D0
(en)
|
2001-11-03 |
2002-01-02 |
Astrazeneca Ab |
Compounds
|
US7319107B2
(en)
|
2001-11-08 |
2008-01-15 |
Johnson & Johnson Consumer Companies, Inc. |
1,2,4-thiadiazolium derivatives as melanocortin receptor modulators
|
GB0128108D0
(en)
|
2001-11-23 |
2002-01-16 |
Astrazeneca Ab |
Therapeutic use
|
NZ533118A
(en)
|
2001-11-27 |
2006-07-28 |
Wyeth Corp |
3-cyanoquinolines as inhibitors of EGF-R and HER2 kinases
|
AU2002347336A1
(en)
|
2001-12-05 |
2003-06-17 |
Astrazeneca Ab |
Quinoline derivatives
|
WO2003047584A1
(en)
|
2001-12-05 |
2003-06-12 |
Astrazeneca Ab |
Quinoline derivatives
|
GB0129099D0
(en)
|
2001-12-05 |
2002-01-23 |
Astrazeneca Ab |
Chemical compounds
|
WO2003050102A1
(en)
|
2001-12-10 |
2003-06-19 |
Aryx Therapeutics |
Novel compounds for the treatment of cardiac arrhythmia, synthesis, and methods of use
|
WO2003049740A1
(en)
|
2001-12-12 |
2003-06-19 |
Pfizer Products Inc. |
Quinazoline derivatives for the treatment of abnormal cell growth
|
EP1456199A1
(en)
|
2001-12-12 |
2004-09-15 |
Pfizer Products Inc. |
Salt forms of e-2-methoxy-n-(3-(4-(3-methyl-pyridin-3-yloxy)-phenylamino)-quinazolin-6-yl)-allyl)-acetamide, its preparation and its use against cancer
|
TW200301123A
(en)
|
2001-12-21 |
2003-07-01 |
Astrazeneca Uk Ltd |
New use
|
AU2002361846A1
(en)
|
2001-12-21 |
2003-07-15 |
Bayer Pharmaceuticals Corporation |
Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
|
BRPI0215312B8
(pt)
|
2001-12-24 |
2021-05-25 |
Astrazeneca Ab |
composto, uso de um composto, composição farmacêutica, e processo para a preparação de um composto
|
JP4445753B2
(ja)
|
2002-01-29 |
2010-04-07 |
グラクソ グループ リミテッド |
アミノピペリジン誘導体
|
WO2003064431A2
(en)
|
2002-01-29 |
2003-08-07 |
Glaxo Group Limited |
Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
|
EP1474420B1
(en)
|
2002-02-01 |
2012-03-14 |
AstraZeneca AB |
Quinazoline compounds
|
DE10204462A1
(de)
|
2002-02-05 |
2003-08-07 |
Boehringer Ingelheim Pharma |
Verwendung von Tyrosinkinase-Inhibitoren zur Behandlung inflammatorischer Prozesse
|
TW200813014A
(en)
|
2002-03-28 |
2008-03-16 |
Astrazeneca Ab |
Quinazoline derivatives
|
DE10217689A1
(de)
|
2002-04-19 |
2003-11-13 |
Boehringer Ingelheim Pharma |
Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, ihre Verwendung und Verfahren zu ihrer Herstellung
|
US6693198B2
(en)
|
2002-04-22 |
2004-02-17 |
Xanthus Life Sciences, Inc. |
Amonafide salts
|
AU2003235838A1
(en)
|
2002-05-01 |
2003-11-17 |
Kirin Beer Kabushiki Kaisha |
Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of macrophage colony stimulating factor receptor
|
US7323479B2
(en)
|
2002-05-17 |
2008-01-29 |
Celgene Corporation |
Methods for treatment and management of brain cancer using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoindoline
|
JP4703183B2
(ja)
|
2002-07-15 |
2011-06-15 |
シンフォニー エボルーション, インク. |
受容体型キナーゼモジュレーターおよびその使用方法
|
GB0219746D0
(en)
|
2002-08-23 |
2002-10-02 |
Inst Of Ex Botany Ascr |
Azapurine derivatives
|
CN1688549A
(zh)
|
2002-08-23 |
2005-10-26 |
麒麟麦酒株式会社 |
具有TGFβ抑制活性的化合物和含所述化合物的药用组合物
|
US7419984B2
(en)
|
2002-10-17 |
2008-09-02 |
Cell Therapeutics, Inc. |
Pyrimidines and uses thereof
|
ES2294317T3
(es)
|
2002-10-21 |
2008-04-01 |
Kirin Pharma Kabushiki Kaisha |
Sal de n-(2-cloro-4-((6,7-dimetoxi-4-quinolil)oxi)fenil)-n'-(5-metil-3-isoxazolil)urea de forma cristalina.
|
JPWO2004039782A1
(ja)
|
2002-10-29 |
2006-03-02 |
麒麟麦酒株式会社 |
Flt3自己リン酸化を阻害するキノリン誘導体およびキナゾリン誘導体並びにそれらを含有する医薬組成物
|
CA2503371C
(en)
|
2002-11-04 |
2011-01-11 |
Astrazeneca Ab |
Quinazoline derivatives as src tyrosine kinase inhibitors
|
AU2003300898A1
(en)
|
2002-12-13 |
2004-07-09 |
Neurogen Corporation |
Carboxylic acid, phosphate or phosphonate substituted quinazolin-4-ylamine analogues as capsaicin receptor modulators
|
PL377686A1
(pl)
|
2002-12-18 |
2006-02-06 |
Pfizer Products Inc. |
Pochodne 4-anilinochinazoliny do leczenia anormalnego wzrostu komórek
|
WO2004058267A1
(en)
|
2002-12-23 |
2004-07-15 |
Ariad Pharmaceuticals, Inc. |
Heterocycles and uses thereof
|
WO2004060373A1
(ja)
|
2002-12-27 |
2004-07-22 |
Santen Pharmaceutical Co., Ltd. |
滲出型加齢黄斑変性治療剤
|
US8176532B1
(en)
|
2003-03-17 |
2012-05-08 |
Sprint Communications Company L.P. |
Secure access point for scada devices
|
JP4960085B2
(ja)
|
2003-03-19 |
2012-06-27 |
エクセリクシス, インク. |
Tie−2モジュレータと使用方法
|
KR100559180B1
(ko)
|
2003-05-20 |
2006-03-14 |
김민서 |
조건부 거래에 따른 전자결제 방법 및 전자결제 서버
|
WO2005003140A1
(en)
|
2003-07-02 |
2005-01-13 |
Pharmacia & Upjohn Company Llc |
4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents
|
US20070213374A1
(en)
|
2003-07-07 |
2007-09-13 |
Merck Patent Gmbh |
Malonamide Derivatives
|
JP4299090B2
(ja)
*
|
2003-09-24 |
2009-07-22 |
株式会社東海理化電機製作所 |
車両用空調装置の操作装置
|
AU2004275842B2
(en)
*
|
2003-09-26 |
2010-09-02 |
Exelixis Inc. |
c-MET modulators and methods of use
|
EP1682529A4
(en)
|
2003-11-07 |
2010-06-30 |
Novartis Vaccines & Diagnostic |
METHODS FOR SYNTHESIS OF QUINOLINONE COMPOUNDS
|
CN101337933B
(zh)
|
2003-12-25 |
2011-03-02 |
卫材R&D管理有限公司 |
喹啉羧酰胺的甲磺酸盐的结晶(a)及其制备方法
|
AU2005207946A1
(en)
|
2004-01-23 |
2005-08-11 |
Amgen Inc. |
Quinoline quinazoline pyridine and pyrimidine counds and their use in the treatment of inflammation angiogenesis and cancer
|
AR047530A1
(es)
|
2004-02-04 |
2006-01-25 |
Novartis Ag |
Formas de sal de 4-(4-metilpiperazin-1-ilmetil)-n-(4-metil-3-(4-piridin-3-il)pirimidin-2-ilamino)fenil)-benzamida
|
US20060035940A1
(en)
|
2004-03-16 |
2006-02-16 |
Sepracor Inc. |
(S)-Amlodipine malate
|
US7173031B2
(en)
|
2004-06-28 |
2007-02-06 |
Bristol-Myers Squibb Company |
Pyrrolotriazine kinase inhibitors
|
JP5368701B2
(ja)
*
|
2004-07-02 |
2013-12-18 |
エクセリクシス、インコーポレイテッド |
c−Metモジュレーター及び使用方法
|
JP2008537784A
(ja)
*
|
2005-03-04 |
2008-09-25 |
カラーリンク・インコーポレイテッド |
4パネル表示システム
|
JP2008537748A
(ja)
|
2005-04-06 |
2008-09-25 |
エクセリクシス、インコーポレイテッド |
c−Metモジュレーター及び使用方法
|
US20080298657A1
(en)
|
2005-11-23 |
2008-12-04 |
Junji Shiraishi |
Computer-Aided Method for Detection of Interval Changes in Successive Whole-Body Bone Scans and Related Computer Program Program Product and System
|
US7723330B2
(en)
|
2006-03-07 |
2010-05-25 |
Array Biopharma Inc. |
Heterobicyclic pyrazole compounds and methods of use
|
WO2007102074A2
(en)
|
2006-03-07 |
2007-09-13 |
Cadila Healthcare Limited |
Salts of quetiapine
|
WO2007109799A2
(en)
|
2006-03-23 |
2007-09-27 |
Teva Pharmaceutical Industries Ltd. |
Polymorphs of eszopiclone malate
|
US20080004273A1
(en)
|
2006-05-30 |
2008-01-03 |
Stephane Raeppel |
Inhibitors of protein tyrosine kinase activity
|
EP2062886B1
(en)
|
2006-08-23 |
2011-11-30 |
Eisai R&D Management Co., Ltd. |
Salt of phenoxypyridine derivative or crystal thereof and process for producing the same
|
WO2008070616A2
(en)
|
2006-12-01 |
2008-06-12 |
University Of Utah Research Foundation |
METHODS AND COMPOSITIONS RELATED TO HIF-1α
|
US7999006B2
(en)
|
2006-12-14 |
2011-08-16 |
Exelixis, Inc. |
Methods of using MEK inhibitors
|
US20080200515A1
(en)
|
2006-12-29 |
2008-08-21 |
Tap Pharmaceutical Products Inc. |
Solid state forms of enantiopure ilaprazole
|
WO2009085972A1
(en)
|
2007-12-19 |
2009-07-09 |
Sepracor Inc. |
Maleate, besylate, and l-malate salts of 6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5h-pyrrolo[3,4-b]pyrazine
|
UY31800A
(es)
|
2008-05-05 |
2009-11-10 |
Smithkline Beckman Corp |
Metodo de tratamiento de cancer usando un inhibidor de cmet y axl y un inhibidor de erbb
|
TW201035017A
(en)
|
2008-09-26 |
2010-10-01 |
Smithkline Beecham Corp |
Preparation of a quinolinyloxydiphenylcyclopropanedicarboxamide
|
AU2009300328A1
(en)
|
2008-10-01 |
2010-04-08 |
Ludwig Institute For Cancer Research |
Methods for the treatment of cancer
|
WO2010056960A1
(en)
|
2008-11-13 |
2010-05-20 |
Exelixis Inc. |
Methods of preparing quinoline derivatives
|
JP2012511017A
(ja)
|
2008-12-04 |
2012-05-17 |
エグゼリクシス, インコーポレイテッド |
キノリン誘導体の調製方法
|
KR102187034B1
(ko)
|
2009-01-16 |
2020-12-04 |
엑셀리시스, 인코포레이티드 |
암 치료용 n-(4-{〔6,7-비스(메틸옥시)퀴놀린-4-일〕옥시}페닐)-n'-(4-플루오로페닐)사이클로프로판-1,1-디카르복사미드의 말산염 및 그 결정형
|
EA201200144A1
(ru)
|
2009-07-17 |
2012-08-30 |
Экселиксис, Инк. |
Кристаллические формы n-[3-фтор-4-({6-(метилокси)-7-[(3-морфолин-4-илпропил)окси]хинолин-4-ил}окси)фенил]-n'-(4-фторфенил)циклопропан-1,1-дикарбоксамида
|
UA108618C2
(uk)
|
2009-08-07 |
2015-05-25 |
|
Застосування c-met-модуляторів в комбінації з темозоломідом та/або променевою терапією для лікування раку
|
EP2475390A4
(en)
|
2009-09-09 |
2014-01-01 |
Quintiles Transnat Corp |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF TYROSINE KINASE RECEPTOR MEDIATION DISEASES OR DISORDERS
|
SG184040A1
(en)
|
2010-03-12 |
2012-10-30 |
Exelixis Inc |
Hydrated crystalline forms of n-[3-fluoro-4-({6-(methyloxy)-7-[(3-morpholin-4-ylpropyl)oxy]-quinolin-4-yl}oxy)phenyl]-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
|
US20120070368A1
(en)
|
2010-04-16 |
2012-03-22 |
Exelixis, Inc. |
Methods of Using C-Met Modulators
|
SG10201609324UA
(en)
|
2010-07-16 |
2017-01-27 |
Exelixis Inc |
C-met modulator pharmaceutical compositions
|
PL2673262T3
(pl)
|
2011-02-10 |
2022-04-11 |
Exelixis, Inc. |
Sposoby wytwarzania związków chinolinowych i kompozycje farmaceutyczne zawierające takie związki
|
US20120252840A1
(en)
|
2011-04-04 |
2012-10-04 |
Exelixis, Inc. |
Method of Treating Cancer
|
KR20140069133A
(ko)
|
2011-09-22 |
2014-06-09 |
엑셀리시스, 인코포레이티드 |
골다공증의 치료방법
|
JP2015515988A
(ja)
|
2012-05-02 |
2015-06-04 |
エクセリクシス, インク. |
溶骨性骨転移を治療するためのmet−vegf二重調節剤
|
US20150238477A1
(en)
|
2012-09-07 |
2015-08-27 |
Exelixis, Inc. |
Method of Treating Lung Adenocarcinoma
|
BR112015025408A8
(pt)
|
2013-04-04 |
2018-07-10 |
Exelixis Inc |
combinações de drogas para tratar câncer
|
WO2015142928A1
(en)
|
2014-03-17 |
2015-09-24 |
Exelixis, Inc. |
Dosing of cabozantinib formulations
|