US4965288A
(en)
|
1988-02-25 |
1990-10-23 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US5059714A
(en)
|
1988-02-25 |
1991-10-22 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US4943593A
(en)
|
1988-02-25 |
1990-07-24 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US5182297A
(en)
|
1988-02-25 |
1993-01-26 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US5252608A
(en)
|
1988-02-25 |
1993-10-12 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US5021456A
(en)
|
1988-02-25 |
1991-06-04 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US5120764A
(en)
|
1988-11-01 |
1992-06-09 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US4997854A
(en)
|
1989-08-25 |
1991-03-05 |
Trustees Of Boston University |
Anti-fibrotic agents and methods for inhibiting the activity of lysyl oxidase in-situ using adjacently positioned diamine analogue substrates
|
US6319494B1
(en)
|
1990-12-14 |
2001-11-20 |
Cell Genesys, Inc. |
Chimeric chains for receptor-associated signal transduction pathways
|
IL104570A0
(en)
|
1992-03-18 |
1993-05-13 |
Yeda Res & Dev |
Chimeric genes and cells transformed therewith
|
CA2246756A1
(en)
|
1996-02-28 |
1997-09-04 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
JP2001002661A
(ja)
|
1999-06-22 |
2001-01-09 |
Ricoh Co Ltd |
ニトリル化合物及びその製造方法
|
JP2001329185A
(ja)
|
1999-06-22 |
2001-11-27 |
Ricoh Co Ltd |
反応生成物、該反応生成物を用いた電子写真感光体、及び該電子写真感光体を用いた電子写真装置と電子写真装置用プロセスカートリッジ
|
AU781880B2
(en)
|
1999-09-17 |
2005-06-16 |
Millennium Pharmaceuticals, Inc. |
Inhibitors of factor Xa
|
US6632815B2
(en)
|
1999-09-17 |
2003-10-14 |
Millennium Pharmaceuticals, Inc. |
Inhibitors of factor Xa
|
AU2001234689A1
(en)
|
2000-02-01 |
2001-08-14 |
Cor Therapeutics, Inc. |
Bivalent phenylene inhibitors of factor xa
|
JP2001335476A
(ja)
|
2000-05-29 |
2001-12-04 |
Shionogi & Co Ltd |
三環化合物の新規用途
|
US6599926B2
(en)
|
2000-06-23 |
2003-07-29 |
Bristol-Myers Squibb Company |
Heteroaryl-phenyl substituted factor Xa inhibitors
|
AU2001288617A1
(en)
|
2000-09-05 |
2002-03-22 |
Neogenesis Pharmaceuticals Inc. |
Methods for forming combinatorial libraries combining amide bond formation with epoxide opening
|
WO2002051775A2
(en)
|
2000-12-22 |
2002-07-04 |
Neogenesis Pharmaceuticals, Inc. |
Methods for forming combinatorial libraries using reductive amination
|
DE10104279A1
(de)
|
2001-01-31 |
2002-08-01 |
Heinz Langhals |
Kompetitive Prionen-Reagenzien und ihre Anwendung in Diagnostik und Therapie
|
FR2828206B1
(fr)
|
2001-08-03 |
2004-09-24 |
Centre Nat Rech Scient |
Utilisation d'inhibiteurs des lysyl oxydases pour la culture cellulaire et le genie tissulaire
|
EP1426046A4
(en)
|
2001-09-14 |
2005-11-02 |
Shionogi & Co |
NEW USE OF TRICYCLIC COMPOUNDS
|
US7446190B2
(en)
|
2002-05-28 |
2008-11-04 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acids encoding chimeric T cell receptors
|
CN1726189A
(zh)
|
2002-12-11 |
2006-01-25 |
伊莱利利公司 |
新颖的mch受体拮抗剂
|
US20040142958A1
(en)
|
2002-12-13 |
2004-07-22 |
Neurogen Corporation |
Combination therapy for the treatment of pain
|
US20060293339A1
(en)
|
2003-03-24 |
2006-12-28 |
Chakravarty Prasun K |
Biaryl substituted 6-membered heterocycles as sodium channel blockers
|
US7244763B2
(en)
|
2003-04-17 |
2007-07-17 |
Warner Lambert Company Llc |
Compounds that modulate PPAR activity and methods of preparation
|
US7405295B2
(en)
|
2003-06-04 |
2008-07-29 |
Cgi Pharmaceuticals, Inc. |
Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds
|
GB0325956D0
(en)
|
2003-11-06 |
2003-12-10 |
Addex Pharmaceuticals Sa |
Novel compounds
|
US7834013B2
(en)
|
2003-11-19 |
2010-11-16 |
Glaxosmithkline Llc |
Aminophenylcyclopropyl carboxylic acids and derivatives as agonists to GPR40
|
CN1930159A
(zh)
|
2004-03-08 |
2007-03-14 |
北卡罗来纳大学查珀尔希尔分校 |
作为抗原生动物药的新的双阳离子咪唑并[1,2-a]吡啶和5,6,7,8-四氢-咪唑并[1,2-a]吡啶化合物
|
WO2005095338A1
(ja)
|
2004-03-30 |
2005-10-13 |
Takeda Pharmaceutical Company Limited |
アルコキシフェニルプロパン酸誘導体
|
USRE44638E1
(en)
|
2004-05-13 |
2013-12-10 |
Icos Corporation |
Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
|
US20060019967A1
(en)
|
2004-07-21 |
2006-01-26 |
Su-Ying Wu |
SARS CoV main protease inhibitors
|
JP2007284350A
(ja)
|
2004-07-27 |
2007-11-01 |
Takeda Chem Ind Ltd |
糖尿病治療剤
|
EP1810677A1
(en)
|
2004-10-08 |
2007-07-25 |
Takeda Pharmaceutical Company Limited |
Receptor function regulating agent
|
AU2005305083B2
(en)
|
2004-11-03 |
2012-02-02 |
Arena Pharmaceuticals, Inc. |
GPR41 and modulators thereof for the treatment of insulin-related disorders
|
US20080090865A1
(en)
|
2005-01-28 |
2008-04-17 |
Min Ge |
Antidiabetic Bicyclic Compounds
|
JP2008528628A
(ja)
|
2005-01-31 |
2008-07-31 |
メルク エンド カムパニー インコーポレーテッド |
抗糖尿病性二環式化合物
|
EP1845988A2
(en)
|
2005-02-11 |
2007-10-24 |
3M Innovative Properties Company |
Substituted imidazoquinolines and imidazonaphthyridines
|
US20090142345A1
(en)
|
2005-03-15 |
2009-06-04 |
Takeda Pharmaceutical Company Limited |
Prophylactic/therapeutic agent for cancer
|
CA3151350A1
(en)
|
2005-05-09 |
2006-11-16 |
E. R. Squibb & Sons, L.L.C. |
Human monoclonal antibodies to programmed death 1 (pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics
|
GB0510141D0
(en)
|
2005-05-18 |
2005-06-22 |
Addex Pharmaceuticals Sa |
Novel compounds B3
|
US7465804B2
(en)
|
2005-05-20 |
2008-12-16 |
Amgen Inc. |
Compounds, pharmaceutical compositions and methods for their use in treating metabolic disorders
|
EA019344B1
(ru)
|
2005-07-01 |
2014-03-31 |
МЕДАРЕКС, Эл.Эл.Си. |
Человеческие моноклональные антитела против лиганда-1 запрограммированной гибели клеток (pd-l1) и их применения
|
US8153694B2
(en)
|
2005-07-29 |
2012-04-10 |
Takeda Pharmaceutical Company Limited |
Cyclopropanecarboxylic acid compound
|
TWI382019B
(zh)
|
2005-08-19 |
2013-01-11 |
Array Biopharma Inc |
作為類鐸受體(toll-like receptor)調節劑之胺基二氮雜呯
|
TWI404537B
(zh)
|
2005-08-19 |
2013-08-11 |
Array Biopharma Inc |
作為類鐸受體(toll-like receptor)調節劑之8-經取代苯并氮雜呯
|
CA2621949A1
(en)
|
2005-09-14 |
2007-03-22 |
Amgen Inc. |
Conformationally constrained 3- (4-hydroxy-phenyl) - substituted-propanoic acids useful for treating metabolic disorders
|
JP2009512701A
(ja)
|
2005-10-19 |
2009-03-26 |
メルク エンド カムパニー インコーポレーテッド |
Cetp阻害薬
|
WO2007049050A2
(en)
|
2005-10-27 |
2007-05-03 |
Heptahelix Ab |
Modulators of gpr40 for the treatment of diabetes
|
JP4990789B2
(ja)
|
2005-11-04 |
2012-08-01 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
Gpr40とホスホリパーゼとを用いる疾患に有用な物質のスクリーニング方法
|
US20100249175A1
(en)
|
2005-12-02 |
2010-09-30 |
Wilson W David |
Dicationic compounds which selectively recognize G-quadruplex DNA
|
WO2007079078A1
(en)
|
2005-12-29 |
2007-07-12 |
Bayer Schering Pharma Aktiengesellschaft |
Diamine derivatives as inhibitors of leukotriene a4 hydrolase
|
EA200801865A1
(ru)
|
2006-02-22 |
2009-02-27 |
Филоджен Спа |
Опухолевые маркеры сосудов
|
JP2009530281A
(ja)
|
2006-03-14 |
2009-08-27 |
アムジエン・インコーポレーテツド |
代謝障害の治療に有用である二環式カルボン酸誘導体
|
DE102006012251A1
(de)
|
2006-03-15 |
2007-11-08 |
Grünenthal GmbH |
Substituierte 4-Amino-chinazolin-Derivate und ihre Verwendung zur Herstellung von Arzneimitteln
|
CA2647107A1
(en)
|
2006-03-23 |
2007-09-27 |
Novartis Ag |
Anti-tumor cell antigen antibody therapeutics
|
MY155275A
(en)
|
2006-03-31 |
2015-09-30 |
Novartis Ag |
4-(4-[6-(trifluoromethyl-pyridin-3-ylamino)-n-containing-heteroaryl]-phenyl)-cyclohexyl)-acetic acid derivatives and pharmaceutical uses thereof
|
TW200815377A
(en)
|
2006-04-24 |
2008-04-01 |
Astellas Pharma Inc |
Oxadiazolidinedione compound
|
EP1849781A1
(en)
|
2006-04-28 |
2007-10-31 |
Laboratorios del Dr. Esteve S.A. |
Substituted 3-Amino-4-hydroxy pyrrolidines compounds, their preparation and use as medicaments
|
MEP43308A
(en)
|
2006-05-09 |
2011-02-10 |
Pfizer Prod Inc |
Cycloalkylamino acid derivatives and pharmaceutical compositions thereof
|
DE102006021872B4
(de)
|
2006-05-11 |
2008-04-17 |
Sanofi-Aventis |
4,5-Diphenyl-pyrimidinyl-oxy oder -mercapto substituierte Carbonsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
WO2007131621A1
(de)
|
2006-05-11 |
2007-11-22 |
Sanofi-Aventis |
4,5-diphenyl-pyrimidinyl substituierte carbonsäuren, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
|
DE102006021874B4
(de)
|
2006-05-11 |
2008-03-27 |
Sanofi-Aventis |
4,5-Diphenyl-pyrimidinyl-amino substituierte Carbonsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
DE102006021878A1
(de)
|
2006-05-11 |
2007-11-15 |
Sanofi-Aventis |
Phenylamino-benzoxazol substituierte Carbonsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
US7442808B2
(en)
|
2006-05-15 |
2008-10-28 |
Merck & Co., Inc. |
Antidiabetic bicyclic compounds
|
CN103083307A
(zh)
|
2006-06-27 |
2013-05-08 |
武田药品工业株式会社 |
稠环化合物
|
WO2008014236A1
(en)
|
2006-07-24 |
2008-01-31 |
Tetralogic Pharmaceuticals Corporation |
Dimeric iap inhibitors
|
US7759495B2
(en)
|
2006-08-11 |
2010-07-20 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
CA2662305C
(en)
|
2006-09-07 |
2012-04-17 |
Amgen Inc. |
Heterocyclic gpr40 modulators
|
WO2008037266A1
(en)
|
2006-09-25 |
2008-04-03 |
Universite Libre De Bruxelles |
Inhibitors of conventional protein kinase c isozymes and use thereof for treating inflammatory diseases
|
WO2008063768A2
(en)
|
2006-10-12 |
2008-05-29 |
Case Western Reserve University |
Compositions and methods for treating metabolic diseases
|
AU2007314405A1
(en)
|
2006-10-31 |
2008-05-08 |
Merck & Co., Inc. |
Antidiabetic bicyclic compounds
|
WO2008054674A2
(en)
|
2006-10-31 |
2008-05-08 |
Merck & Co., Inc. |
Antidiabetic bicyclic compounds
|
US7750048B2
(en)
|
2006-11-15 |
2010-07-06 |
Janssen Pharmaceutica Nv |
GPR40 agonists
|
WO2008065409A2
(en)
|
2006-12-01 |
2008-06-05 |
Betagenon Ab |
Combination for use in the treatment of cancer, comprising tamoxifen or an aromatase inhibitor
|
TW200838526A
(en)
|
2006-12-01 |
2008-10-01 |
Astellas Pharma Inc |
Carboxylic acid derivatives
|
EP2099789A4
(en)
|
2006-12-04 |
2012-02-15 |
Boehringer Ingelheim Int |
INHIBITORS OF HIV REPLICATION
|
CA2671315A1
(en)
|
2006-12-11 |
2008-06-19 |
Novartis Ag |
Method of preventing or treating myocardial ischemia by inhibiting dgat1 enzyme with a dgat1 inhibitor
|
CA2672438A1
(en)
|
2006-12-20 |
2008-07-03 |
Amgen Inc. |
Substituted heterocycles and methods of use
|
US8513270B2
(en)
|
2006-12-22 |
2013-08-20 |
Incyte Corporation |
Substituted heterocycles as Janus kinase inhibitors
|
ES2548353T3
(es)
|
2006-12-28 |
2015-10-15 |
Abbvie Inc. |
Inhibidores de poli(ADP-ribosa)polimerasa
|
WO2008090327A1
(en)
|
2007-01-22 |
2008-07-31 |
Betagenon Ab |
New combination for use in the treatment of cancer
|
WO2008090356A1
(en)
|
2007-01-25 |
2008-07-31 |
Betagenon Ab |
Thiazolidinone derivatives useful in the treatment of cancer and disorders caused by excess adiposity
|
WO2008106202A1
(en)
|
2007-02-27 |
2008-09-04 |
Housey Gerard M |
Theramutein modulators
|
WO2008109943A1
(en)
|
2007-03-12 |
2008-09-18 |
Cytopia Research Pty Ltd |
Phenyl amino pyrimidine compounds and uses thereof
|
JP2010524932A
(ja)
|
2007-04-16 |
2010-07-22 |
アムジエン・インコーポレーテツド |
置換ビフェニルフェノキシ−、チオフェニル−及びアミノフェニルプロパン酸gpr40調節物質
|
WO2008139987A1
(ja)
|
2007-04-26 |
2008-11-20 |
Japan Science And Technology Agency |
Gタンパク質共役型レセプタ-作動剤
|
US20090214529A9
(en)
|
2007-05-22 |
2009-08-27 |
Taigen Biotechnology Co., Ltd. |
Kinesin inhibitors
|
WO2008144925A1
(en)
|
2007-05-30 |
2008-12-04 |
Aegera Therapeutics Inc. |
Iap bir domain binding compounds
|
EP2002838A1
(de)
|
2007-06-13 |
2008-12-17 |
Bayer Schering Pharma AG |
Verwendung von Aryl/Hetarylamid-Derivaten als Modulatoren des EP2-Rezeptors
|
WO2008156656A2
(en)
|
2007-06-13 |
2008-12-24 |
State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University |
Method for making biaryl compounds, compounds made by the method, and method for their use
|
EA021463B1
(ru)
|
2007-06-29 |
2015-06-30 |
Джилид Сайэнс, Инк. |
Пуриновые производные и их применение в качестве модуляторов толл-подобного рецептора 7
|
PE20091008A1
(es)
|
2007-08-02 |
2009-08-10 |
Amgen Inc |
Derivados heterociclicos como moduladores de fosfoinositida 3-cinasa
|
HUE025283T2
(en)
|
2007-08-02 |
2016-03-29 |
Gilead Biologics Inc |
LOX and LOX2 inhibitors and their use
|
TWI649303B
(zh)
|
2007-08-17 |
2019-02-01 |
杜邦股份有限公司 |
製備4-乙醯基-n-〔2-側氧基-2-〔(2,2,2-三氟乙基)胺基〕乙基〕-1-萘甲醯胺之化合物及方法
|
WO2009038204A1
(ja)
|
2007-09-17 |
2009-03-26 |
Pharma Frontier Co., Ltd. |
新規長鎖脂肪酸誘導体化合物及びそれら化合物を有効成分とするgタンパク質共役型レセプター作動剤
|
MX2010002461A
(es)
|
2007-09-21 |
2010-03-26 |
Sanofi Aventis |
(carboxilalquilenfenil)feniloxamidas, metodo para su produccion y uso de las mismas como medicamento.
|
MX2010002419A
(es)
|
2007-09-21 |
2010-03-30 |
Sanofi Aventis |
(ciclopropilfenil) feniloxamidas, metodo para su produccion y uso como un medicamento.
|
US8501955B2
(en)
|
2007-10-08 |
2013-08-06 |
Advinus Therapeutics Private Limited |
Acetamide derivatives as glucokinase activators, their process and medicinal application
|
WO2009048527A1
(en)
|
2007-10-10 |
2009-04-16 |
Amgen Inc. |
Substituted biphenyl gpr40 modulators
|
JP2011016722A
(ja)
|
2007-10-23 |
2011-01-27 |
Astellas Pharma Inc |
チアゾリジンジオン化合物
|
US8304547B2
(en)
|
2007-10-24 |
2012-11-06 |
Astellas Pharma Inc. |
Azolecarboxamide compound or salt thereof
|
MX2010004435A
(es)
|
2007-10-26 |
2010-05-13 |
Japan Tobacco Inc |
Compuestos espiro y uso farmaceutico de los mismos.
|
WO2009058237A1
(en)
|
2007-10-29 |
2009-05-07 |
Merck & Co., Inc. |
Antidiabetic tricyclic compounds
|
US8147818B2
(en)
|
2008-02-13 |
2012-04-03 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7704992B2
(en)
|
2008-02-13 |
2010-04-27 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
CA2716352C
(en)
|
2008-03-06 |
2013-05-28 |
Amgen Inc. |
Conformationally constrained carboxylic acid derivatives useful for treating metabolic disorders
|
WO2009112445A1
(en)
|
2008-03-10 |
2009-09-17 |
Novartis Ag |
Method of increasing cellular phosphatidyl choline by dgat1 inhibition
|
KR101927291B1
(ko)
|
2008-07-08 |
2018-12-10 |
인사이트 홀딩스 코포레이션 |
인돌아민 2,3-디옥시게나아제의 억제제로서의 1,2,5-옥사디아졸
|
US8450460B2
(en)
|
2008-07-21 |
2013-05-28 |
Apogenix Gmbh |
Single-chain TNFSF fusion polypeptides
|
CN105152919A
(zh)
|
2008-07-28 |
2015-12-16 |
赛丹思科大学 |
用于治疗代谢疾病的化合物
|
ES2438496T3
(es)
|
2008-08-01 |
2014-01-17 |
Ventirx Pharmaceuticals, Inc. |
Formulaciones de agonistas de receptores de tipo toll y su uso
|
US8652843B2
(en)
|
2008-08-12 |
2014-02-18 |
Oncomed Pharmaceuticals, Inc. |
DDR1-binding agents and methods of use thereof
|
DE102008037790A1
(de)
|
2008-08-14 |
2010-02-18 |
Merck Patent Gmbh |
Bicyclische Triazolderivate
|
WO2010039238A1
(en)
|
2008-10-01 |
2010-04-08 |
Synta Pharmaceuticals Corp. |
Compounds for inflammation and immune-related uses
|
AU2009303475B2
(en)
|
2008-10-15 |
2012-09-13 |
Amgen Inc. |
Spirocyclic GPR40 modulators
|
CA2745843A1
(en)
|
2008-12-08 |
2010-06-17 |
Hamid Hoveyda |
Compounds, pharmaceutical composition and methods for use in treating metabolic disorders
|
US8450321B2
(en)
|
2008-12-08 |
2013-05-28 |
Gilead Connecticut, Inc. |
6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
|
PE20120106A1
(es)
|
2008-12-09 |
2012-02-20 |
Gilead Sciences Inc |
Moduladores de receptores tipo toll
|
CA2740193A1
(en)
|
2008-12-23 |
2010-07-01 |
Abbott Laboratories |
Anti-viral compounds
|
MX2011007543A
(es)
|
2009-01-19 |
2011-09-06 |
Daiichi Sankyo Co Ltd |
Compuesto ciclico que contiene heteroatomos.
|
AU2010206783A1
(en)
|
2009-01-23 |
2011-07-28 |
Merck Sharp & Dohme Corp. |
Pentafluorosulpholane-containing antidiabetic compounds
|
AU2010206786A1
(en)
|
2009-01-23 |
2011-07-28 |
Merck Sharp & Dohme Corp. |
Bridged and fused heterocyclic antidiabetic compounds
|
WO2010085528A1
(en)
|
2009-01-23 |
2010-07-29 |
Schering Corporation |
Bridged and fused antidiabetic compounds
|
AR075051A1
(es)
|
2009-02-05 |
2011-03-02 |
Schering Corp |
Compuestos antidiabeticos que contienen ftalazina
|
EP2393359A4
(en)
|
2009-02-09 |
2012-10-03 |
Enanta Pharm Inc |
COMPOUND DIBENZIMIDAZOLE DERIVATIVES
|
WO2010096462A1
(en)
|
2009-02-17 |
2010-08-26 |
Enanta Pharmaceuticals, Inc |
Linked diimidazole derivatives
|
JP5628841B2
(ja)
|
2009-02-27 |
2014-11-19 |
エナンタ ファーマシューティカルズ インコーポレイテッド |
C型肝炎ウイルスインヒビター
|
CN102427726B
(zh)
|
2009-03-27 |
2014-10-08 |
普雷西迪奥制药公司 |
丙型肝炎的稠环抑制剂
|
JP2012136438A
(ja)
|
2009-04-22 |
2012-07-19 |
Astellas Pharma Inc |
テトラゾール化合物
|
JPWO2010123016A1
(ja)
|
2009-04-22 |
2012-10-25 |
アステラス製薬株式会社 |
カルボン酸化合物
|
KR20140122705A
(ko)
|
2009-05-13 |
2014-10-20 |
길리애드 사이언시즈, 인코포레이티드 |
항바이러스 화합물
|
US20120172351A1
(en)
|
2009-06-09 |
2012-07-05 |
Nobuyuki Negoro |
Novel fused cyclic compound and use thereof
|
ES2414934T3
(es)
|
2009-06-11 |
2013-07-23 |
Abbvie Bahamas Limited |
Inhibidores del virus de la Hepatitis C
|
TWI491606B
(zh)
|
2009-07-13 |
2015-07-11 |
Gilead Sciences Inc |
調節細胞凋亡信號之激酶的抑制劑
|
DK2467380T3
(en)
|
2009-08-18 |
2017-03-13 |
Ventirx Pharmaceuticals Inc |
SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS
|
RU2016125705A
(ru)
|
2009-08-18 |
2018-12-04 |
Вентиркс Фармасьютикалз, Инк. |
Замещенные бензоазепины в качестве модуляторов тoll-подобных рецепторов
|
GB0914856D0
(en)
|
2009-08-25 |
2009-09-30 |
Ark Therapeutics Ltd |
Compounds
|
EP2475254A4
(en)
|
2009-09-11 |
2013-05-22 |
Enanta Pharm Inc |
HEPATITIS C-VIRUS HEMMER
|
NO2477987T3
(pt)
|
2009-09-14 |
2018-06-09 |
|
|
JP2013506714A
(ja)
|
2009-10-06 |
2013-02-28 |
ブリストル−マイヤーズ スクイブ カンパニー |
ピロリジンgpr40モジュレーター
|
AR078522A1
(es)
|
2009-10-15 |
2011-11-16 |
Lilly Co Eli |
Compuesto de espiropiperidina, composicion farmaceutica que lo comprende, su uso para preparar un medicamento util para tratar diabetes y compuesto intermediario para su sintesis
|
PL2491035T3
(pl)
|
2009-10-22 |
2018-01-31 |
Gilead Sciences Inc |
Pochodne puryny lub deazapuryny przydatne do leczenia (między innymi) infekcji wirusowych
|
US8455500B2
(en)
|
2009-10-30 |
2013-06-04 |
Mochida Pharmaceutical Co., Ltd. |
3-hydroxy-5-arylisoxazole derivative
|
WO2011057214A2
(en)
|
2009-11-09 |
2011-05-12 |
Neurogenetic Pharmaceuticals, Inc. |
Gamma-secretase modulatory compounds, methods for identifying same, and uses therefor
|
AU2010324871A1
(en)
|
2009-11-25 |
2012-06-14 |
Merck Sharp & Dohme Corp. |
Fused tricyclic compounds and derivatives thereof useful for the treatment of viral diseases
|
AR078948A1
(es)
|
2009-11-30 |
2011-12-14 |
Lilly Co Eli |
Compuestos de espiropiperidina, composicion farmaceutica que lo comprenden y su uso para preparar un medicamento util para tratar la diabetes
|
RS56751B1
(sr)
|
2009-12-18 |
2018-04-30 |
Ogeda Sa |
Derivati pirolidin karboksilne kiseline kao agonisti g-protein spojenog receptora 43 (gpr43), farmaceutska kompozicija i postupci za upotrebu u lečenju metaboličkih poremećaja
|
WO2011076734A1
(en)
|
2009-12-21 |
2011-06-30 |
Euroscreen S.A. |
Compounds, pharmaceutical composition and methods for use in treating inflammatory diseases
|
WO2011076732A1
(en)
|
2009-12-21 |
2011-06-30 |
Euroscreen S.A. |
Compounds, pharmaceutical composition and methods for use in treating gastrointestinal disorders
|
AU2010336225A1
(en)
|
2009-12-25 |
2012-08-16 |
Mochida Pharmaceutical Co.,Ltd. |
Novel 3-hydroxy-5-arylisothiazole derivative
|
WO2011080755A1
(en)
|
2009-12-29 |
2011-07-07 |
Advinus Therapeutics Private Limited |
Fused nitrogen heterocyclic compounds, process of preparation and uses thereof
|
WO2011082400A2
(en)
|
2010-01-04 |
2011-07-07 |
President And Fellows Of Harvard College |
Modulators of immunoinhibitory receptor pd-1, and methods of use thereof
|
WO2011092284A1
(en)
|
2010-01-29 |
2011-08-04 |
Euroscreen S.A. |
Novel amino acid derivatives and their use as gpr43 receptor modulators
|
WO2011097513A1
(en)
|
2010-02-04 |
2011-08-11 |
Gilead Biologics, Inc |
Antibodies that bind to lysyl oxidase-like 2 (loxl2) and methods of use therefor
|
WO2011106573A2
(en)
|
2010-02-24 |
2011-09-01 |
Oryzon Genomics, S.A. |
Lysine demethylase inhibitors for diseases and disorders associated with hepadnaviridae
|
MX2012010919A
(es)
|
2010-03-24 |
2013-02-01 |
Vertex Pharma |
Analogos para el tratamiento o prevencion de infecciones por flavivirus.
|
EP2550262A1
(en)
|
2010-03-24 |
2013-01-30 |
Vertex Pharmaceuticals Incorporated |
Analogues for the treatment or prevention of flavivirus infections
|
TW201136916A
(en)
|
2010-03-30 |
2011-11-01 |
Novartis Ag |
New uses
|
US8686048B2
(en)
|
2010-05-06 |
2014-04-01 |
Rhizen Pharmaceuticals Sa |
Immunomodulator and anti-inflammatory compounds
|
EP2568809A4
(en)
|
2010-05-12 |
2013-11-06 |
Univ Vanderbilt |
MGLUR4-SULFONATED HETEROCYCLIC ALLOSTERIC POTENTIALIZERS, COMPOSITIONS THEREFOR, AND METHODS FOR TREATING NEUROLOGICAL DYSFUNCTION
|
JP6050746B2
(ja)
|
2010-05-13 |
2016-12-21 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
Gタンパク質共役受容体活性を示すグルカゴンスーパーファミリーのペプチド
|
US9089520B2
(en)
|
2010-05-21 |
2015-07-28 |
Baylor College Of Medicine |
Methods for inducing selective apoptosis
|
ES2592152T3
(es)
|
2010-05-31 |
2016-11-28 |
Ono Pharmaceutical Co., Ltd. |
Derivado de purinona como inhibidor de Btk quinasa
|
WO2011151436A2
(en)
|
2010-06-04 |
2011-12-08 |
Euroscreen S.A. |
Novel compounds, method for use them and pharmaceutical composition containing them
|
US8530413B2
(en)
|
2010-06-21 |
2013-09-10 |
Sanofi |
Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
|
TW201215388A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
JP2012036168A
(ja)
|
2010-07-15 |
2012-02-23 |
Daiichi Sankyo Co Ltd |
ヘテロ原子を有する環状化合物を含有する医薬組成物
|
US8932980B2
(en)
|
2010-07-20 |
2015-01-13 |
Council Of Scientific & Industrial Research |
Ordered mesoporous titanosilicate and the process for the preparation thereof
|
EP2595613B1
(en)
|
2010-07-22 |
2019-01-09 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Compounds for use in a method of preventing or treating viral infection
|
SG10201506703VA
(en)
|
2010-08-27 |
2015-10-29 |
Gilead Biologics Inc |
Antibodies To Matrix Metalloproteinase 9
|
JP5850503B2
(ja)
|
2010-09-14 |
2016-02-03 |
北海道公立大学法人 札幌医科大学 |
筋ジストロフィーを処置するための組成物
|
US8999967B2
(en)
|
2010-09-29 |
2015-04-07 |
Presidio Pharmaceuticals, Inc. |
Tricyclic fused ring inhibitors of hepatitis C
|
CA2812787A1
(en)
|
2010-10-01 |
2012-04-05 |
Robert Hershberg |
Methods for the treatment of allergic diseases
|
WO2012045090A2
(en)
|
2010-10-01 |
2012-04-05 |
Ventirx Pharmaceuticals, Inc. |
Therapeutic use of a tlr agonist and combination therapy
|
JP5809157B2
(ja)
|
2010-10-08 |
2015-11-10 |
持田製薬株式会社 |
環状アミド誘導体
|
EP2640701B1
(en)
|
2010-11-15 |
2017-07-05 |
Bayer Intellectual Property GmbH |
Cyanoenamines and their use as fungicides
|
EP3284741A1
(en)
|
2010-11-17 |
2018-02-21 |
Gilead Pharmasset LLC |
Antiviral compounds
|
WO2012068589A2
(en)
|
2010-11-19 |
2012-05-24 |
Constellation Pharmaceuticals |
Modulators of methyl modifying enzymes, compositions and uses thereof
|
HUE025363T2
(en)
|
2010-12-01 |
2016-02-29 |
Boehringer Ingelheim Int |
Indanyl Oxide Hydrobenzofuranylacetic Acids that can be used to treat metabolic syndrome
|
WO2012078802A1
(en)
|
2010-12-08 |
2012-06-14 |
Takeda Pharmaceutical Company Limited |
PREPARATION OF SUBSTITUTED-4,5-DIHYDROPYRROLO[4,3,2-de][2,6]NAPHTHYRIDIN-3(1H)-ONES
|
TR201820015T4
(tr)
|
2010-12-09 |
2019-01-21 |
Univ Pennsylvania |
Kanser Tedavisi İçin Kimerik Antijen Reseptörü-Modifiye Edilmiş T Hücrelerinin Kullanılması
|
UY33775A
(es)
|
2010-12-10 |
2012-07-31 |
Gilead Sciences Inc |
Inhibidores macrocíclicos de virus flaviviridae, composiciones farmacéuticas que los comprenden y sus usos
|
WO2012083053A2
(en)
|
2010-12-15 |
2012-06-21 |
Abbott Laboratories |
Anti-viral compounds
|
EP2651920A4
(en)
|
2010-12-15 |
2014-12-17 |
Abbvie Inc |
ANTI-VIRAL COMPOUNDS
|
EP2651923A4
(en)
|
2010-12-15 |
2014-06-18 |
Abbvie Inc |
ANTI-VIRAL COMPOUNDS
|
US20150232455A1
(en)
|
2010-12-15 |
2015-08-20 |
Allan C. Krueger |
Anti-viral compounds
|
EP2651928A4
(en)
|
2010-12-15 |
2014-06-18 |
Abbvie Inc |
ANTI-VIRAL COMPOUNDS
|
EP2655334B1
(en)
|
2010-12-22 |
2018-10-03 |
Eutropics Pharmaceuticals, Inc. |
Compositions and methods useful for treating diseases
|
DK2663550T3
(en)
|
2011-01-12 |
2017-03-27 |
Ventirx Pharmaceuticals Inc |
SUBSTITUTED BENZOAZEPINS AS MODULATORS OF TOLL-LIKE RECEPTORS
|
PL2663555T4
(pl)
|
2011-01-12 |
2017-08-31 |
Ventirx Pharmaceuticals, Inc. |
Podstawione benzoazepiny jako modulatory receptora toll-podobnego
|
BR112013018286A2
(pt)
|
2011-01-19 |
2016-11-16 |
Galapagos Nv |
derivados d azetidina úteis para o tratamento de doenças metabólicas e inflamatórias
|
SG192126A1
(en)
|
2011-01-25 |
2013-09-30 |
Univ Michigan |
Bcl-2/bcl-xl inhibitors and therapeutic methods using the same
|
EP2672820B1
(en)
|
2011-02-07 |
2019-04-17 |
The Washington University |
Mannoside compounds and methods of use thereof
|
AP2013007110A0
(en)
|
2011-02-12 |
2013-09-30 |
Globeimmune Inc |
Yeast-based therapeutic for chronic hepatitis B infection
|
EA201391180A1
(ru)
|
2011-02-17 |
2014-01-30 |
Такеда Фармасьютикал Компани Лимитед |
Способ получения оптически активных производных дигидробензофурана
|
US9464065B2
(en)
|
2011-03-24 |
2016-10-11 |
The Scripps Research Institute |
Compounds and methods for inducing chondrogenesis
|
CN104470886A
(zh)
|
2011-04-08 |
2015-03-25 |
赛丹思科大学 |
用于治疗代谢疾病的邻-氟取代的化合物
|
CA2832685C
(en)
|
2011-04-08 |
2020-09-01 |
Janssen R&D Ireland |
Pyrimidine derivatives for the treatment of viral infections
|
TW201247636A
(en)
|
2011-04-27 |
2012-12-01 |
Mochida Pharm Co Ltd |
Novel 3-hydroxyisothiazole 1-oxide derivatives
|
WO2012154608A1
(en)
|
2011-05-06 |
2012-11-15 |
Intellikine, Llc |
Reactive mtor and pi3 kinase inhibitors and uses thereof
|
JP5659189B2
(ja)
|
2011-05-13 |
2015-01-28 |
富士フイルム株式会社 |
非共鳴2光子吸収材料、非共鳴2光子吸収記録材料、記録媒体、記録再生方法及び非共鳴2光子吸収化合物
|
NO2709989T3
(pt)
|
2011-05-18 |
2018-05-19 |
|
|
TWI567061B
(zh)
|
2011-07-01 |
2017-01-21 |
吉李德科學股份有限公司 |
用於治療成癮之化合物
|
EP2817304A4
(en)
|
2011-07-14 |
2015-01-21 |
Biochromix Newco Ab |
NOVEL COMPOUNDS AND THEIR THERAPEUTIC USE
|
TWI537262B
(zh)
|
2011-08-17 |
2016-06-11 |
美國禮來大藥廠 |
供治療糖尿病使用之新穎1,2,3,4-四氫喹啉衍生物
|
US9550835B2
(en)
|
2011-08-23 |
2017-01-24 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-DDR1 antibody having anti-tumor activity
|
GB201115529D0
(en)
|
2011-09-08 |
2011-10-26 |
Imp Innovations Ltd |
Antibodies, uses and methods
|
AU2012318580A1
(en)
|
2011-10-04 |
2014-05-22 |
Gilead Calistoga Llc |
Novel quinoxaline inhibitors of PI3K
|
WO2013057743A1
(en)
|
2011-10-21 |
2013-04-25 |
Connexios Life Sciences Pvt. Ltd |
Process for the preparation of an aryl oxime and salts thereof
|
WO2013081016A1
(ja)
|
2011-11-29 |
2013-06-06 |
小野薬品工業株式会社 |
プリノン誘導体塩酸塩
|
BR112014015197A2
(pt)
|
2011-12-21 |
2017-06-13 |
Novira Therapeutics Inc |
agentes antivirais de hepatite b
|
EP2800736A1
(en)
|
2012-01-04 |
2014-11-12 |
Sanofi |
3-[4-(phenylaminooxalylamino)phenyl]hex-4-ynoic acids, process for preparation thereof and use thereof as a medicament
|
CA2860353A1
(en)
|
2012-01-12 |
2013-07-18 |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
Polycyclic derivatives, preparation method and medical uses thereof
|
US9326973B2
(en)
|
2012-01-13 |
2016-05-03 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
MX2014008591A
(es)
|
2012-01-16 |
2014-08-22 |
Vertex Pharma |
Piperidinamidas piranoespirociclicas como moduladores de canales de iones.
|
UY34573A
(es)
|
2012-01-27 |
2013-06-28 |
Gilead Sciences Inc |
Inhibidor de la quinasa que regula la señal de la apoptosis
|
WO2013116562A1
(en)
|
2012-02-03 |
2013-08-08 |
Gilead Calistoga Llc |
Compositions and methods of treating a disease with (s)-4 amino-6-((1-(5-chloro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile
|
JP6283320B2
(ja)
|
2012-02-08 |
2018-02-21 |
ヤンセン・サイエンシズ・アイルランド・ユーシー |
ウイルス感染の治療のためのピペリジノ−ピリミジン誘導体
|
JP6121339B2
(ja)
|
2012-02-13 |
2017-04-26 |
武田薬品工業株式会社 |
芳香環化合物
|
WO2013122028A1
(ja)
|
2012-02-13 |
2013-08-22 |
武田薬品工業株式会社 |
芳香環化合物
|
MX2014010272A
(es)
|
2012-02-28 |
2015-08-14 |
Piramal Entpr Ltd |
Derivados del acido fenil alcanoico como agonistas gpr.
|
US8642585B2
(en)
|
2012-03-26 |
2014-02-04 |
Boehringer Ingelheim International Gmbh |
Indanyloxydihydrobenzofuranylacetic acids
|
RU2014142598A
(ru)
|
2012-03-31 |
2016-05-27 |
Ф. Хоффманн-Ля Рош Аг |
Новые 4-метилдигидропиримидины для лечения и профилактики инфекции вируса гепатита в
|
US20130267517A1
(en)
|
2012-03-31 |
2013-10-10 |
Hoffmann-La Roche Inc. |
Novel 4-methyl-dihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
WO2013154163A1
(ja)
|
2012-04-11 |
2013-10-17 |
持田製薬株式会社 |
新規5-アリール-1,2-チアジナン誘導体
|
US8809376B2
(en)
|
2012-04-30 |
2014-08-19 |
Boehringer Ingelheim International Gmbh |
Indanyloxydihydrobenzofuranylacetic acids
|
JP2015516436A
(ja)
|
2012-05-11 |
2015-06-11 |
アッヴィ・インコーポレイテッド |
Nampt阻害薬
|
AR091023A1
(es)
|
2012-05-11 |
2014-12-30 |
Abbvie Inc |
Inhibidores del nampt
|
US8633182B2
(en)
*
|
2012-05-30 |
2014-01-21 |
Boehringer Ingelheim International Gmbh |
Indanyloxyphenylcyclopropanecarboxylic acids
|
KR20150040265A
(ko)
|
2012-06-08 |
2015-04-14 |
길리애드 사이언시즈, 인코포레이티드 |
플라비비리대 바이러스의 마크로시클릭 저해제
|
BR112014030649A2
(pt)
|
2012-06-08 |
2017-06-27 |
Gilead Sciences Inc |
inibidores macrocíclicos da flaviviridae vírus
|
AR091279A1
(es)
|
2012-06-08 |
2015-01-21 |
Gilead Sciences Inc |
Inhibidores macrociclicos de virus flaviviridae
|
WO2014014530A1
(en)
|
2012-07-17 |
2014-01-23 |
Mylari Banavara L |
Ursolic acid salts for treating diabetes and obesity
|
JP2015127299A
(ja)
|
2012-07-19 |
2015-07-09 |
武田薬品工業株式会社 |
固形製剤
|
WO2014019186A1
(en)
|
2012-08-02 |
2014-02-06 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
MY183534A
(en)
|
2012-08-10 |
2021-02-25 |
Janssen Sciences Ireland Uc |
Alkylpyrimidine derivatives for the treatment of viral infections and further diseases
|
EP2888239B1
(en)
|
2012-08-27 |
2018-11-28 |
Allergan, Inc. |
Reduced central corneal thickening by use of hydrophilic ester prodrugs of beta-chlorocyclopentanes
|
TWI696606B
(zh)
|
2012-08-28 |
2020-06-21 |
愛爾蘭商健生科學愛爾蘭無限公司 |
胺磺醯基-芳醯胺類及其做為治療b型肝炎之醫藥劑的用途
|
PL2890683T3
(pl)
|
2012-08-28 |
2017-06-30 |
Janssen Sciences Ireland Uc |
Pochodne skondensowanego bicyklicznego sulfamylu i ich zastosowanie jako leki do leczenia wirusowego zapalenia wątroby typu B
|
WO2014037480A1
(en)
|
2012-09-10 |
2014-03-13 |
F. Hoffmann-La Roche Ag |
6-amino acid heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
US20140073631A1
(en)
|
2012-09-12 |
2014-03-13 |
Vymed Corporation |
Antiviral and antimicrobial compounds
|
TW201427995A
(zh)
|
2012-09-24 |
2014-07-16 |
Gilead Sciences Inc |
抗ddr1抗體
|
EP3150582A1
(en)
|
2012-10-02 |
2017-04-05 |
Gilead Sciences, Inc. |
Inhibitors of histone demethylases
|
KR102280595B1
(ko)
|
2012-10-10 |
2021-07-22 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
바이러스 감염 및 다른 질환 치료를 위한 피롤로[3,2-d]피리미딘 유도체
|
EP2911669B1
(en)
|
2012-10-26 |
2024-04-10 |
The University of Chicago |
Synergistic combination of immunologic inhibitors for the treatment of cancer
|
US20140128333A1
(en)
|
2012-11-02 |
2014-05-08 |
Maqui New Life S.A. |
Compounds, Compositions, and Methods for Decreasing Intestinal Glucose Uptake and Inducing Incretin Release
|
TWI692469B
(zh)
|
2012-11-09 |
2020-05-01 |
南韓商Lg化學股份有限公司 |
Gpr40受體促效劑,製造該促效劑的方法以及含有該促效劑作爲活性劑的醫藥組成物
|
KR101268466B1
(ko)
|
2012-11-12 |
2013-06-04 |
유병수 |
사축형 윈드 터빈
|
EA201590949A1
(ru)
|
2012-11-16 |
2015-08-31 |
Бристол-Майерс Сквибб Компани |
Дигидропиразольные модуляторы gpr40
|
MX358499B
(es)
|
2012-11-16 |
2018-08-23 |
Bristol Myers Squibb Co |
Moduladores de dihidropirazol del receptor acoplado a la proteína g (gpr40).
|
CN105121426B
(zh)
|
2012-11-16 |
2017-03-29 |
百时美施贵宝公司 |
吡咯烷gpr40调节剂
|
CN105051018B
(zh)
|
2012-11-16 |
2019-09-20 |
爱尔兰詹森科学公司 |
用于治疗病毒性感染的杂环的经取代的2-氨基-喹唑啉衍生物
|
CN104884452A
(zh)
|
2012-11-20 |
2015-09-02 |
沃泰克斯药物股份有限公司 |
用作吲哚胺2,3-二氧化酶的抑制剂的化合物
|
PE20150968A1
(es)
|
2012-11-28 |
2015-07-09 |
Boehringer Ingelheim Int |
Nuevos acidos indaniloxi dihidrobenzofuranil aceticos
|
EP3763367A1
(en)
|
2012-12-06 |
2021-01-13 |
Celgene Quanticel Research, Inc. |
Pyridine-pyrazole derivatives as histone demethylase inhibitors
|
JP6283862B2
(ja)
|
2012-12-07 |
2018-02-28 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
新規インダニルオキシジヒドロベンゾフラニル酢酸
|
PL2934145T3
(pl)
|
2012-12-19 |
2018-04-30 |
Celgene Quanticel Research, Inc. |
Inhibitory demetylazy histonowej
|
TW201437203A
(zh)
|
2012-12-21 |
2014-10-01 |
Gilead Calistoga Llc |
磷脂醯肌醇3-激酶之抑制劑
|
MX2015007997A
(es)
|
2012-12-21 |
2016-02-18 |
Quanticel Pharmaceuticals Inc |
Inhibidores de histona desmetilasa.
|
US9018221B2
(en)
|
2012-12-21 |
2015-04-28 |
Gilead Calistoga, Llc |
Phosphatidylinositol 3-kinase inhibitors
|
EP2953681B1
(en)
|
2013-02-06 |
2017-03-15 |
Boehringer Ingelheim International GmbH |
New indanyloxydihydrobenzofuranylacetic acids
|
DK2958900T3
(da)
|
2013-02-21 |
2019-07-01 |
Janssen Sciences Ireland Unlimited Co |
2-aminopyrimidinderivater til behandling af virusinfektioner
|
CA2898482A1
(en)
|
2013-02-22 |
2014-08-28 |
Linda L. Brockunier |
Antidiabetic bicyclic compounds
|
US9642843B2
(en)
|
2013-02-27 |
2017-05-09 |
The Regents Of The University Of Michigan |
Pharmaceutical compounds and use of same in cancer and tauopathies
|
SI2961736T1
(en)
|
2013-02-27 |
2018-06-29 |
Gilead Sciences, Inc. |
Histone demethylase inhibitors
|
CA2899706C
(en)
|
2013-02-28 |
2021-10-19 |
Janssen Sciences Ireland Uc |
Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis b
|
CN108017603B
(zh)
|
2013-02-28 |
2021-07-23 |
株式会社蒂奥姆生物 |
三环化合物及其用途
|
WO2014165128A2
(en)
|
2013-03-12 |
2014-10-09 |
Novira Therapeutics, Inc. |
Hepatitis b antiviral agents
|
US9738637B2
(en)
|
2013-03-12 |
2017-08-22 |
Celgene Quantical Research, Inc. |
Histone demethylase inhibitors
|
EP2970307B1
(en)
|
2013-03-13 |
2020-03-11 |
Genentech, Inc. |
Pyrazolo compounds and uses thereof
|
AU2014236711A1
(en)
|
2013-03-14 |
2015-09-17 |
Celgene Quanticel Research, Inc. |
Histone demethylase inhibitors
|
SI2970211T1
(sl)
|
2013-03-15 |
2017-12-29 |
Quanticel Pharmaceuticals Inc. |
Inhibitorji histon demetilaze
|
US9763905B2
(en)
|
2013-03-15 |
2017-09-19 |
The Children's Medical Center Corporation |
Therapeutic target for the treatment of cancers and related therapies and methods
|
CN104059039B
(zh)
|
2013-03-22 |
2017-03-15 |
正大天晴药业集团股份有限公司 |
具有gpr40受体功能调节作用的稠环化合物
|
DK2981536T3
(en)
|
2013-04-03 |
2017-09-25 |
Janssen Sciences Ireland Uc |
N-PHENYLC CARBOXAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICINES FOR THE TREATMENT OF HEPATITIS B
|
CN104109115B
(zh)
|
2013-04-16 |
2016-11-23 |
中国科学院上海药物研究所 |
一种含氮杂环链接的苯丙酸类化合物、其药物组合物、制备方法和用途
|
AR096041A1
(es)
|
2013-04-17 |
2015-12-02 |
Piramal Entpr Ltd |
Derivados de ácido carboxílico alquilo sustituidos como agonistas rpg
|
KR101569522B1
(ko)
|
2013-04-18 |
2015-11-17 |
현대약품 주식회사 |
신규한 3-(4-(벤질옥시)페닐)헥스-4-이노익 산 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 대사성 질환의 예방 또는 치료용 약학적 조성물
|
TWI527811B
(zh)
|
2013-05-09 |
2016-04-01 |
吉李德科學股份有限公司 |
作爲溴結構域抑制劑的苯並咪唑衍生物
|
SI2997019T1
(sl)
|
2013-05-17 |
2018-12-31 |
Janssen Sciences Ireland Uc, |
Derivati sulfamoiliofenamida in njihova uporaba kot zdravila za zdravljenje hepatitisa B
|
JO3603B1
(ar)
|
2013-05-17 |
2020-07-05 |
Janssen Sciences Ireland Uc |
مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي
|
EA201592126A1
(ru)
|
2013-05-17 |
2016-05-31 |
Ф. Хоффманн-Ля Рош Аг |
6-мостиковые гетероарилдигидропиримидины для лечения и профилактики заражения вирусом гепатита b
|
WO2014187343A1
(zh)
|
2013-05-22 |
2014-11-27 |
四川海思科制药有限公司 |
苯并呋喃衍生物、其制备方法及其在医药上的应用
|
CN105308034B
(zh)
|
2013-06-14 |
2017-10-31 |
吉利德科学公司 |
磷脂酰肌醇3‑激酶抑制剂
|
CN104507921B
(zh)
|
2013-07-02 |
2017-02-22 |
四川海思科制药有限公司 |
苯并环丁烯类衍生物、其制备方法及其在医药上的应用
|
US10478445B2
(en)
|
2013-07-03 |
2019-11-19 |
Georgetown University |
Boronic acid derivatives of resveratrol for activating deacetylase enzymes
|
US20160145304A1
(en)
|
2013-07-12 |
2016-05-26 |
Helmholtz-Zentrum für Infektionsforschung GmbH |
Cystobactamides
|
KR102244937B1
(ko)
|
2013-07-25 |
2021-04-27 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
글리옥사미드 치환된 피롤아미드 유도체 및 b형 간염 치료용 의약으로서의 이의 용도
|
CN105143181B
(zh)
|
2013-07-26 |
2017-12-26 |
四川海思科制药有限公司 |
三元并环羧酸类衍生物、其制备方法及其在医药上的应用
|
US9657023B2
(en)
|
2013-07-30 |
2017-05-23 |
Gilead Connecticut, Inc. |
Polymorph of Syk inhibitors
|
WO2015020184A1
(ja)
|
2013-08-09 |
2015-02-12 |
武田薬品工業株式会社 |
芳香環化合物
|
CN104418801B
(zh)
|
2013-08-19 |
2016-10-05 |
上海润诺生物科技有限公司 |
苯并哌啶环与苯并吗啉环类化合物、其制法及医药应用
|
CN105473595A
(zh)
|
2013-08-23 |
2016-04-06 |
福建海西新药创制有限公司 |
治疗糖尿病的羧酸化合物
|
WO2015031036A1
(en)
|
2013-08-26 |
2015-03-05 |
Purdue Pharma L.P. |
Azaspiro[4.5] decane derivatives and use thereof
|
WO2015028960A1
(en)
|
2013-08-28 |
2015-03-05 |
Piramal Enterprises Limited |
Substituted heterocyclic derivatives as gpr agonists and uses thereof
|
CN105246875A
(zh)
|
2013-09-03 |
2016-01-13 |
四川海思科制药有限公司 |
茚满衍生物及其制备方法和在医药上的应用
|
JP6417419B2
(ja)
|
2013-09-04 |
2018-11-07 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
免疫調節剤として有用な化合物
|
MY186438A
(en)
|
2013-09-06 |
2021-07-22 |
Aurigene Discovery Tech Ltd |
1, 2, 4-oxadiazole derivatives as immunomodulators
|
PL3043865T3
(pl)
|
2013-09-11 |
2021-07-05 |
Institut National De La Santé Et De La Recherche Médicale (Inserm) |
SPOSOBY I KOMPOZYCjE FARMACEUTYCZNE W LECZENIU ZAKAŻENIA WIRUSEM ZAPALENIA WĄTROBY TYPU B
|
JP6533778B2
(ja)
|
2013-09-26 |
2019-06-19 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Gpr40アゴニストとしてのインダニルオキシジヒドロベンゾフラニル酢酸誘導体を調製するための方法および中間体
|
WO2015051496A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
EP3060547B1
(en)
|
2013-10-23 |
2017-10-11 |
Janssen Sciences Ireland UC |
Carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
|
WO2015062486A1
(en)
|
2013-10-31 |
2015-05-07 |
Sunshine Lake Pharma Co., Ltd. |
Biphenyl compounds and uses thereof
|
WO2015073774A1
(en)
|
2013-11-14 |
2015-05-21 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis b infections
|
AP2016009176A0
(en)
|
2013-11-14 |
2016-04-30 |
Cadila Healthcare Ltd |
Novel heterocyclic compounds
|
US10519115B2
(en)
|
2013-11-15 |
2019-12-31 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
WO2015076800A1
(en)
|
2013-11-21 |
2015-05-28 |
Ptc Therapeutics, Inc. |
Substituted pyridine and pyrazine bmi-1 inhibitors
|
EP3074008B1
(en)
|
2013-11-27 |
2019-09-04 |
Epics Therapeutics |
Compounds, pharmaceutical composition and methods for use in treating inflammation
|
WO2015078802A1
(en)
|
2013-11-28 |
2015-06-04 |
Boehringer Ingelheim International Gmbh |
New indanyloxyphenylcyclopropanecarboxylic acids
|
US9957219B2
(en)
|
2013-12-04 |
2018-05-01 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
WO2015085238A1
(en)
|
2013-12-05 |
2015-06-11 |
The Regents Of The University Of California, A California Corporation |
Inhibitors of lpxc
|
TW201609722A
(zh)
|
2013-12-13 |
2016-03-16 |
美國禮來大藥廠 |
新穎***并吡啶化合物
|
WO2015089809A1
(en)
|
2013-12-19 |
2015-06-25 |
Merck Sharp & Dohme Corp. |
Antidiabetic substituted heteroaryl compounds
|
UY35898A
(es)
|
2013-12-23 |
2015-07-31 |
Gilead Sciences Inc |
?compuestos inhibidores de syk y composiciones que los comprenden?.
|
US9290505B2
(en)
|
2013-12-23 |
2016-03-22 |
Gilead Sciences, Inc. |
Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
|
EP3092240B1
(en)
|
2014-01-10 |
2018-12-05 |
Eli Lilly and Company |
Isopropyl triazolo pyridine compounds
|
EP3092241B1
(en)
|
2014-01-10 |
2017-10-04 |
Eli Lilly and Company |
Phenyl-triazolo-pyridine compounds
|
US9169212B2
(en)
|
2014-01-16 |
2015-10-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
US9181288B2
(en)
|
2014-01-16 |
2015-11-10 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
JP2017504633A
(ja)
|
2014-01-30 |
2017-02-09 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
B型肝炎ウイルス感染の治療及び予防のための新規なジヒドロキノリジノン
|
JP6495929B2
(ja)
|
2014-02-06 |
2019-04-03 |
ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー |
スルファモイルピロールアミド誘導体およびb型肝炎の治療のための医薬としてのその使用
|
WO2015119899A1
(en)
|
2014-02-06 |
2015-08-13 |
Merck Sharp & Dohme Corp. |
Antidiabetic compounds
|
LT3114128T
(lt)
|
2014-03-07 |
2019-03-25 |
F. Hoffmann-La Roche Ag |
Nauji 6 padėtyje kondensuoti heteroarildihidropirimidinai, skirti hepatito b virusinės infekcijos gydymui ir profilaktikai
|
WO2015140717A1
(en)
|
2014-03-18 |
2015-09-24 |
Iteos Therapeutics |
Novel 3-indol substituted derivatives, pharmaceutical compositions and methods for use
|
US9400280B2
(en)
|
2014-03-27 |
2016-07-26 |
Novira Therapeutics, Inc. |
Piperidine derivatives and methods of treating hepatitis B infections
|
AU2015239886B2
(en)
|
2014-04-04 |
2018-02-01 |
Iomet Pharma Ltd |
Indole derivatives for use in medicine
|
MX2016013144A
(es)
|
2014-04-10 |
2017-04-27 |
Seattle Children's Hospital (Dba Seattle Children's Res Institute) |
Metodo y composiciones para inmunoterapia celular.
|
US9850225B2
(en)
|
2014-04-14 |
2017-12-26 |
Bristol-Myers Squibb Company |
Compounds useful as immunomodulators
|
US10301260B2
(en)
|
2014-05-07 |
2019-05-28 |
Bristol-Myers Squibb Company |
Pyrrolidine GPR40 modulators
|
SG11201609170UA
(en)
|
2014-05-07 |
2016-12-29 |
Bristol Myers Squibb Co |
Pyrrolidine gpr40 modulators for the treatment of diseases such as diabetes
|
EP3140297B1
(en)
|
2014-05-07 |
2018-04-11 |
Bristol-Myers Squibb Company |
Pyrrolidine gpr40 modulators for the treatment of diseases such as diabetes
|
KR20160148715A
(ko)
|
2014-05-13 |
2016-12-26 |
에프. 호프만-라 로슈 아게 |
B형 간염 바이러스 감염의 치료 또는 예방을 위한 신규한 다이하이드로퀴놀리진온
|
WO2015176267A1
(en)
|
2014-05-22 |
2015-11-26 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
WO2015188085A1
(en)
|
2014-06-06 |
2015-12-10 |
Flexus Biosciences, Inc. |
Immunoregulatory agents
|
US10471028B2
(en)
|
2014-06-13 |
2019-11-12 |
University Of Rochester |
Small molecule efflux pump inhibitors
|
GB201411239D0
(en)
|
2014-06-25 |
2014-08-06 |
Takeda Pharmaceutical |
Novel compounds
|
GB201411236D0
(en)
|
2014-06-25 |
2014-08-06 |
Takeda Pharmaceutical |
Novel compounds
|
TW201613878A
(en)
|
2014-07-09 |
2016-04-16 |
Janssen Pharmaceutica Nv |
Pyrazine GPR40 agonists for the treatment of type II diabetes
|
WO2016012470A1
(en)
|
2014-07-25 |
2016-01-28 |
F. Hoffmann-La Roche Ag |
New amorphous and crystalline forms of (3s)-4-[[(4r)-4-(2-chloro-4-fluoro-phenyl)-5-methoxycarbonyl-2-thiazol-2-yl-1, 4-dihydropyrimidin-6-yl]methyl]morpholine-3-carboxylic acid
|
US10011572B2
(en)
|
2014-07-29 |
2018-07-03 |
Merck Sharp & Dohme Corp. |
Monocyclic isoxazolines as inhibitors of cholesterol ester transfer protein
|
WO2016019587A1
(en)
|
2014-08-08 |
2016-02-11 |
Merck Sharp & Dohme Corp. |
[7, 6]-fused bicyclic antidiabetic compounds
|
EP3177285B1
(en)
|
2014-08-08 |
2020-09-23 |
Merck Sharp & Dohme Corp. |
[5,6]-fused bicyclic antidiabetic compounds
|
WO2016022742A1
(en)
|
2014-08-08 |
2016-02-11 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
EP3177282B1
(en)
|
2014-08-08 |
2021-10-06 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
MX2017001862A
(es)
|
2014-08-14 |
2017-05-15 |
Hoffmann La Roche |
Nuevas piridazonas y triazinonas para el tratamiento y la profilaxis de infeccion por virus de hepatitis b.
|
GB201414730D0
(en)
|
2014-08-19 |
2014-10-01 |
Tpp Global Dev Ltd |
Pharmaceutical compound
|
AU2015306662A1
(en)
|
2014-08-27 |
2017-03-09 |
Gilead Sciences, Inc. |
Compounds and methods for inhibiting histone demethylases
|
WO2016032120A1
(ko)
|
2014-08-27 |
2016-03-03 |
씨제이헬스케어 주식회사 |
신규한 아미노-페닐-설포닐-아세테이트 유도체 및 이의 용도
|
TWI805109B
(zh)
|
2014-08-28 |
2023-06-11 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
AU2014405919B2
(en)
|
2014-09-11 |
2020-02-20 |
Bristol-Myers Squibb Company |
Macrocyclic inhibitors of the PD-1/PD-L1 and CD80 (B7-1)/PD-Li protein/protein interactions
|
UY35733A
(es)
|
2014-09-12 |
2016-04-01 |
Bristol Myers Squibb Company Una Corporación Del Estado De Delaware |
Inhibidores macrocíclicos de las interacciones proteína/proteína pd-1/pd-l1 y cd80(b7-1)/pd-l1 i.p.c.
|
TW201625527A
(zh)
|
2014-09-19 |
2016-07-16 |
財團法人臺灣基督長老教會馬偕紀念社會事業基金會馬偕紀念醫院 |
苯并雜環化合物及其應用
|
JP6499282B2
(ja)
|
2014-09-26 |
2019-04-10 |
ギリアード サイエンシーズ, インコーポレイテッド |
Tank結合キナーゼ阻害剤化合物として有用なアミノトリアジン誘導体
|
EP3204379B1
(en)
|
2014-10-10 |
2019-03-06 |
Genentech, Inc. |
Pyrrolidine amide compounds as histone demethylase inhibitors
|
EP3206691B1
(en)
|
2014-10-14 |
2018-09-19 |
Sunshine Lake Pharma Co., Ltd. |
Substituted heteroaryl compounds and methods of use
|
CN111423408A
(zh)
|
2014-10-17 |
2020-07-17 |
现代药品株式会社 |
代谢性疾病的预防或治疗用复合制剂
|
US9688629B2
(en)
*
|
2014-10-24 |
2017-06-27 |
Bristol-Myers Squibb Company |
Indole carboxamide compounds
|
KR101857146B1
(ko)
|
2014-10-28 |
2018-05-11 |
삼성에스디아이 주식회사 |
유기 광전자 소자 및 표시 장치
|
AU2015341913B2
(en)
|
2014-11-03 |
2020-07-16 |
Iomet Pharma Ltd |
Pharmaceutical compound
|
GB201419579D0
(en)
|
2014-11-03 |
2014-12-17 |
Iomet Pharma Ltd |
Pharmaceutical compound
|
US9637485B2
(en)
|
2014-11-03 |
2017-05-02 |
Hoffmann-La Roche Inc. |
6,7-dihydrobenzo[a]quinolizin-2-one derivatives for the treatment and prophylaxis of hepatitis B virus infection
|
UY36391A
(es)
|
2014-11-05 |
2016-06-01 |
Flexus Biosciences Inc |
Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido1), sus métodos de síntesis y composiciones farmacèuticas que las contienen
|
UY36390A
(es)
|
2014-11-05 |
2016-06-01 |
Flexus Biosciences Inc |
Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen
|
US9856292B2
(en)
|
2014-11-14 |
2018-01-02 |
Bristol-Myers Squibb Company |
Immunomodulators
|
EP3766895A1
(en)
|
2014-12-03 |
2021-01-20 |
Juno Therapeutics, Inc. |
Methods and compositions for adoptive cell therapy
|
EP3227337A1
(en)
|
2014-12-05 |
2017-10-11 |
F. Hoffmann-La Roche AG |
Methods and compositions for treating cancer using pd-1 axis antagonists and hpk1 antagonists
|
WO2016100236A2
(en)
|
2014-12-15 |
2016-06-23 |
Bellicum Pharmaceuticals, Inc. |
Methods for controlled elimination of therapeutic cells
|
US9676793B2
(en)
|
2014-12-23 |
2017-06-13 |
Hoffmann-Laroche Inc. |
Co-crystals of 5-amino-2-oxothiazolo[4,5-d]pyrimidin-3(2H)-yl-5-hydroxymethyl tetrahydrofuran-3-yl acetate and methods for preparing and using the same
|
WO2016102438A1
(en)
|
2014-12-23 |
2016-06-30 |
F. Hoffmann-La Roche Ag |
Process for the preparation of 4-phenyl-5-alkoxycarbonyl-2-thiazol-2-yl-1,4-dihydropyrimidine analogues
|
EP3240537B1
(en)
|
2014-12-30 |
2020-09-09 |
F. Hoffmann-La Roche AG |
Novel tetrahydropyridopyrimidines and tetrahydropyridopyridines for the treatment and prophylaxis of hepatitis b virus infection
|
JP2018504891A
(ja)
|
2014-12-31 |
2018-02-22 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
リアルタイムPCRによる細胞溶解物からのHBV cccDNA定量化のための新規ハイスループット法
|
EP3242878B1
(en)
|
2015-01-08 |
2020-10-14 |
Impetis Biosciences Ltd. |
Bicyclic compounds, compositions and medicinal applications thereof
|
MA41338B1
(fr)
|
2015-01-16 |
2019-07-31 |
Hoffmann La Roche |
Composés de pyrazine pour le traitement de maladies infectieuses
|
WO2016120186A1
(en)
|
2015-01-27 |
2016-08-04 |
F. Hoffmann-La Roche Ag |
Recombinant hbv cccdna, the method to generate thereof and the use thereof
|
US20160222060A1
(en)
|
2015-02-04 |
2016-08-04 |
Bristol-Myers Squibb Company |
Immunomodulators
|
CA2981753A1
(en)
|
2015-02-06 |
2016-08-11 |
Unity Biotechnology, Inc. |
Compounds and uses in treatment of senescence-associated conditions
|
EP3256471B1
(en)
|
2015-02-11 |
2018-12-12 |
F. Hoffmann-La Roche AG |
Novel 2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis b virus infection
|
WO2016128908A1
(en)
|
2015-02-12 |
2016-08-18 |
Advinus Therapeutics Limited |
Bicyclic compounds, compositions and medicinal applications thereof
|
EP3267993A4
(en)
|
2015-03-10 |
2018-08-08 |
Aurigene Discovery Technologies Limited |
Therapeutic cyclic compounds as immunomodulators
|
CA2979137C
(en)
|
2015-03-10 |
2023-12-19 |
Aurigene Discovery Technologies Limited |
1,2,4-oxadiazole and thiadiazole compounds as immunomodulators
|
CU20170117A7
(es)
|
2015-03-10 |
2018-05-08 |
Aurigene Discovery Tech Ltd |
COMPUESTOS TIADIAZOL y 1,3,4-OXADIAZOL 3-SUSTITUIDOS COMO INMUNOMODULADORES
|
EP3267999A4
(en)
|
2015-03-10 |
2018-07-25 |
Aurigene Discovery Technologies Limited |
1,3,4-oxadiazole and thiadiazole compounds as immunomodulators
|
BR112017019304A2
(pt)
|
2015-03-10 |
2018-05-08 |
Aurigene Discovery Technologies Limited |
compostos de 1,2,4-oxadiazol 3-substituído e tiadiazol como imunomoduladores
|
CN104876912B
(zh)
|
2015-04-08 |
2017-07-21 |
苏州云轩医药科技有限公司 |
Wnt信号通路抑制剂及其应用
|
MX2017014613A
(es)
|
2015-05-15 |
2018-03-01 |
Gilead Sciences Inc |
Compuestos de bencimidazol e imadazopiridin-carboximidamida que tienen actividad como inhibidores de indolamina 2,3-dioxigenasa.
|
CA2986060A1
(en)
|
2015-05-29 |
2016-12-08 |
Valerie Odegard |
Composition and methods for regulating inhibitory interactions in genetically engineered cells
|
TWI703150B
(zh)
|
2015-06-04 |
2020-09-01 |
美商庫拉腫瘤技術股份有限公司 |
用於抑制menin及mll蛋白之交互作用的方法及組合物
|
CN107709336B
(zh)
|
2015-06-12 |
2021-06-22 |
杭州英创医药科技有限公司 |
作为Syk抑制剂和/或Syk-HDAC双重抑制剂的杂环化合物
|
EP3322420B1
(en)
|
2015-07-13 |
2021-12-29 |
Merck Sharp & Dohme Corp. |
Bicyclic heterocycles as inhibitors of cholesterol ester transfer protein
|
EP3331860B1
(en)
|
2015-08-07 |
2019-07-17 |
Boehringer Ingelheim International GmbH |
Indanylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
|
US9908873B2
(en)
|
2015-08-12 |
2018-03-06 |
Janssen Pharmaceutica Nv |
GPR40 agonists for the treatment of type II diabetes
|
WO2017027309A1
(en)
|
2015-08-12 |
2017-02-16 |
Janssen Pharmaceutica Nv |
Gpr40 agonists for the treatment of type ii diabetes
|
WO2017027312A1
(en)
|
2015-08-12 |
2017-02-16 |
Janssen Pharmaceutica Nv |
Gpr40 agonists for the treatment of type ii diabetes
|
WO2017031392A1
(en)
|
2015-08-20 |
2017-02-23 |
University Of Florida Research Foundation, Incorporated |
Lipid compounds for treatment of obesity, hypertension and metabolic syndrome
|
JP2018526405A
(ja)
|
2015-09-09 |
2018-09-13 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
[{[2,3−ジヒドロ−1H−インデン−1−イル]アミノ}−2H,3H−フロ[3,2−b]ピリジン−3−イル]酢酸、それらの医薬組成物および使用
|
CA2999070A1
(en)
|
2015-09-17 |
2017-03-23 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
US10745382B2
(en)
|
2015-10-15 |
2020-08-18 |
Bristol-Myers Squibb Company |
Compounds useful as immunomodulators
|
ES2928164T3
(es)
|
2015-10-19 |
2022-11-15 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
CA3004083A1
(en)
|
2015-11-04 |
2017-05-11 |
Incyte Corporation |
Pharmaceutical compositions and methods for indoleamine 2,3-dioxygenase inhibition and indications therefor
|
EP3377488B1
(en)
|
2015-11-19 |
2022-08-10 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
EP4218819A3
(en)
|
2015-12-07 |
2023-08-23 |
Kyoto University |
Combination therapy based on pd-1 signal inhibitors
|
TW201726623A
(zh)
|
2015-12-17 |
2017-08-01 |
英塞特公司 |
作為免疫調節劑之雜環化合物
|
KR20180100585A
(ko)
|
2015-12-22 |
2018-09-11 |
인사이트 코포레이션 |
면역조절제로서의 헤테로사이클릭 화합물
|
WO2017107979A1
(en)
|
2015-12-24 |
2017-06-29 |
Genentech, Inc. |
Tdo2 inhibitors
|
EP3190103A1
(en)
|
2016-01-08 |
2017-07-12 |
Rijksuniversiteit Groningen |
Inhibitors of the pd-1/pd-l1 protein/protein interaction
|
CA3014774A1
(en)
|
2016-02-17 |
2017-08-24 |
Children's Medical Center Corporation |
Ffa1 (gpr40) as a therapeutic target for neural angiogenesis diseases or disorders
|
US10143746B2
(en)
|
2016-03-04 |
2018-12-04 |
Bristol-Myers Squibb Company |
Immunomodulators
|
US9798514B2
(en)
|
2016-03-09 |
2017-10-24 |
Spotify Ab |
System and method for color beat display in a media content environment
|
WO2017162284A1
(de)
|
2016-03-23 |
2017-09-28 |
Symrise Ag |
Homovanillinsäure-ester zum reduzieren oder inhibieren der fettsäureaufnahme im dünndarm
|
WO2017172505A1
(en)
|
2016-03-29 |
2017-10-05 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
US10358463B2
(en)
|
2016-04-05 |
2019-07-23 |
Bristol-Myers Squibb Company |
Immunomodulators
|
US10195178B2
(en)
|
2016-04-11 |
2019-02-05 |
Janssen Pharmaceutica Nv |
GPR40 agonists in anti-diabetic drug combinations
|
WO2017180571A1
(en)
|
2016-04-11 |
2017-10-19 |
Janssen Pharmaceutica Nv |
Substituted benzothiophenyl derivatives as gpr40 agonists for the treatment of type ii diabetes
|
WO2017180769A1
(en)
|
2016-04-13 |
2017-10-19 |
Capten Therapeutics Inc. |
Small molecules for immunogenic treatment of cancer
|
WO2017192961A1
(en)
*
|
2016-05-06 |
2017-11-09 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
KR102456572B1
(ko)
|
2016-05-23 |
2022-10-19 |
인스티튜드 오브 머테리아 메디카, 차이니스 아케데미 오브 메디컬 싸이언시스 |
벤질 페닐 에테르 유도체, 그 제조 방법 및 약제학적 조성물 및 용도
|
WO2017201683A1
(en)
|
2016-05-25 |
2017-11-30 |
Merck Sharp & Dohme Corp. |
Substituted tetrahydroisoquinoline compounds useful as gpr120 agonists
|
MA45116A
(fr)
|
2016-05-26 |
2021-06-02 |
Incyte Corp |
Composés hétérocycliques comme immunomodulateurs
|
US20190144545A1
(en)
|
2016-05-26 |
2019-05-16 |
Merck Patent Gmbh |
PD-1/PD-L1 Inhibitors for Cancer Treatment
|
PE20190731A1
(es)
|
2016-06-20 |
2019-05-23 |
Incyte Corp |
Compuestos heterociclicos como inmunomoduladores
|
US10639284B2
(en)
|
2016-06-27 |
2020-05-05 |
Chemocentryx, Inc. |
Immunomodulator compounds
|
SG11201900077QA
(en)
|
2016-07-08 |
2019-02-27 |
Bristol Myers Squibb Co |
1,3-dihydroxy-phenyl derivatives useful as immunomodulators
|
WO2018026971A1
(en)
|
2016-08-03 |
2018-02-08 |
Arising International, Llc |
Symmetric or semi-symmetric compounds useful as immunomodulators
|
EP3281937A1
(en)
|
2016-08-09 |
2018-02-14 |
Dompé farmaceutici S.p.A. |
Sulfonamides as gpr40- and gpr120-agonists
|
US10563620B2
(en)
|
2016-08-12 |
2020-02-18 |
Rolls-Royce North American Technologies Inc. |
Expandable exhaust cone
|
US20180057486A1
(en)
|
2016-08-29 |
2018-03-01 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
US10734026B2
(en)
|
2016-09-01 |
2020-08-04 |
Facebook, Inc. |
Systems and methods for dynamically providing video content based on declarative instructions
|
US10144706B2
(en)
|
2016-09-01 |
2018-12-04 |
Bristol-Myers Squibb Company |
Compounds useful as immunomodulators
|
US20180065917A1
(en)
*
|
2016-09-02 |
2018-03-08 |
Polaris Pharmaceuticals, Inc. |
Immune checkpoint inhibitors, compositions and methods thereof
|
WO2018051254A1
(en)
|
2016-09-14 |
2018-03-22 |
Aurigene Discovery Technologies Limited |
Cyclic substituted-1,2,4-oxadiazole compounds as immunomodulators
|
WO2018051255A1
(en)
|
2016-09-14 |
2018-03-22 |
Aurigene Discovery Technologies Limited |
Cyclic substituted-1,3,4-oxadiazole and thiadiazole compounds as immunomodulators
|
WO2018053302A1
(en)
|
2016-09-19 |
2018-03-22 |
Ensemble Therapeutics Corporation |
Macrocyclic compounds for the inhibition of indoleamine-2,3-dioxygenase activity and use thereof
|
US10988433B2
(en)
|
2016-10-25 |
2021-04-27 |
Janssen Pharmaceutica Nv |
Cyclohexyl GPR40 agonists for the treatment of type II diabetes
|
CN110088089B
(zh)
|
2016-10-25 |
2023-08-29 |
勃林格殷格翰国际有限公司 |
苄基氨基吡啶基环丙烷甲酸、药物组合物及其用途
|
WO2018095877A1
(en)
|
2016-11-28 |
2018-05-31 |
Boehringer Ingelheim International Gmbh |
Indanylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
|
WO2018106518A1
(en)
|
2016-12-06 |
2018-06-14 |
Merck Sharp & Dohme Corp. |
Antidiabetic heterocyclic compounds
|
KR102007633B1
(ko)
|
2016-12-15 |
2019-08-06 |
일동제약(주) |
신규 페닐 프로피온 산 유도체 및 이의 용도
|
ES2891528T3
(es)
|
2016-12-20 |
2022-01-28 |
Bristol Myers Squibb Co |
Compuestos útiles como inmunomoduladores
|
RU2019122602A
(ru)
|
2016-12-20 |
2021-01-22 |
Мерк Шарп И Доум Корп. |
Комбинации антагонистов pd-1 и циклических динуклеотидных агонистов sting для лечения рака
|
US10968232B2
(en)
|
2016-12-20 |
2021-04-06 |
Merck Sharp & Dohme Corp. |
Antidiabetic spirochroman compounds
|
WO2018119266A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Benzooxazole derivatives as immunomodulators
|
US20180179202A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
PE20200005A1
(es)
|
2016-12-22 |
2020-01-06 |
Incyte Corp |
Derivados de tetrahidro imidazo[4,5-c]piridina como inductores de internalizacion pd-l1
|
WO2018119236A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Triazolo[1,5-a]pyridine derivatives as immunomodulators
|
US20180177784A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
WO2018119221A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Pyridine derivatives as immunomodulators
|
WO2018121560A1
(zh)
|
2016-12-29 |
2018-07-05 |
深圳微芯生物科技有限责任公司 |
脲类化合物、其制备方法及其应用
|
JP7050792B2
(ja)
|
2017-01-26 |
2022-04-08 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ベンジルオキシピラジニルシクロプロパンカルボン酸、その医薬組成物及び使用
|
JP7050791B2
(ja)
|
2017-01-26 |
2022-04-08 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ベンジルオキシピリジルシクロプロパンカルボン酸、その医薬組成物及び使用
|
JP7023969B2
(ja)
|
2017-01-26 |
2022-02-22 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ベンジルアミノピリジルシクロプロパンカルボン酸、その医薬組成物及び使用
|
CN110248929B
(zh)
|
2017-01-26 |
2023-05-12 |
勃林格殷格翰国际有限公司 |
苄基氨基吡嗪基环丙烷甲酸、其药物组合物和用途
|
EP3573965B1
(en)
|
2017-01-26 |
2021-06-23 |
Boehringer Ingelheim International GmbH |
Indanylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
|
CN110300755B
(zh)
|
2017-02-08 |
2022-10-04 |
勃林格殷格翰国际有限公司 |
茚满基氨基氮杂二氢苯并呋喃乙酸、用于治疗糖尿病的药物组合物
|
JP7132937B2
(ja)
|
2017-03-15 |
2022-09-07 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Hpk1の阻害剤としてのアザインドール
|
GB201704714D0
(en)
|
2017-03-24 |
2017-05-10 |
Caldan Therapeutics Ltd |
Pharmaceutical compounds
|
EP3601258B1
(en)
|
2017-03-27 |
2023-08-30 |
Bristol-Myers Squibb Company |
Substituted isoquionline derivatives as immunomudulators
|
JP7129420B6
(ja)
|
2017-03-30 |
2024-02-02 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Hpk1阻害剤としてのイソキノリン
|
TW201904964A
(zh)
|
2017-03-30 |
2019-02-01 |
瑞士商赫孚孟拉羅股份公司 |
作為hpk1之抑制劑的啶
|
AR111199A1
(es)
|
2017-03-31 |
2019-06-12 |
Takeda Pharmaceuticals Co |
Compuesto aromático agonista de gpr40
|
WO2018181847A1
(ja)
|
2017-03-31 |
2018-10-04 |
武田薬品工業株式会社 |
芳香環化合物
|
JOP20180040A1
(ar)
*
|
2017-04-20 |
2019-01-30 |
Gilead Sciences Inc |
مثبطات pd-1/pd-l1
|
CN108794422B
(zh)
|
2017-04-26 |
2022-07-01 |
南京圣和药业股份有限公司 |
作为pd-l1抑制剂的杂环类化合物
|
WO2019008156A1
(en)
|
2017-07-07 |
2019-01-10 |
Rijksuniversiteit Groningen |
INHIBITORS OF PROTEIN / PROTEIN INTERACTION PD-1 / PD-L1
|
AU2018306619B2
(en)
|
2017-07-28 |
2022-06-02 |
Chemocentryx, Inc. |
Immunomodulator compounds
|
ES2926540T3
(es)
|
2017-08-08 |
2022-10-26 |
Chemocentryx Inc |
Inmunomoduladores macrocíclicos
|
WO2019034172A1
(zh)
|
2017-08-18 |
2019-02-21 |
上海轶诺药业有限公司 |
一种具有pd-l1抑制活性的化合物、其制备方法及用途
|
US20200216542A1
(en)
|
2017-09-20 |
2020-07-09 |
Chugai Seiyaku Kabushiki Kaisha |
Dosage regimen for combination therapy using pd-1 axis binding antagonists and gpc3 targeting agent
|
US11492375B2
(en)
|
2017-10-03 |
2022-11-08 |
Bristol-Myers Squibb Company |
Cyclic peptide immunomodulators
|
WO2019074241A1
(ko)
|
2017-10-11 |
2019-04-18 |
정원혁 |
페닐아세틸렌 유도체를 포함하는 pd-1과 pd-l1의 상호작용 억제제
|
CN109678796B
(zh)
|
2017-10-19 |
2023-01-10 |
上海长森药业有限公司 |
Pd-1/pd-l1小分子抑制剂及其制备方法和用途
|
JP7293560B2
(ja)
|
2017-12-29 |
2023-06-20 |
グアンジョウ マキシノベル ファーマシューティカルズ カンパニー リミテッド |
芳香族ビニルまたは芳香族エチル系誘導体、その製造方法、中間体、薬物組成物および使用
|
PE20210640A1
(es)
|
2018-02-13 |
2021-03-23 |
Gilead Sciences Inc |
Inhibidores pd-1/pd-l1
|
MA51232A
(fr)
|
2018-02-22 |
2020-10-07 |
Chemocentryx Inc |
Indane-amines utiles en tant qu'antagonistes de pd-l1
|
CN111788193B
(zh)
|
2018-03-13 |
2023-04-04 |
广东东阳光药业有限公司 |
Pd-1/pd-l1类小分子抑制剂及其在药物中的应用
|
CA3093527A1
(en)
|
2018-03-13 |
2019-09-19 |
Jubilant Prodel LLC |
Bicyclic compounds as inhibitors of pd1/pd-l1 interaction/activation
|
AU2019245288C1
(en)
|
2018-03-30 |
2024-01-18 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
JP7242702B2
(ja)
|
2018-04-19 |
2023-03-20 |
ギリアード サイエンシーズ, インコーポレイテッド |
Pd-1/pd-l1阻害剤
|
AU2019267824B2
(en)
|
2018-05-11 |
2023-10-05 |
Incyte Corporation |
Tetrahydro-imidazo(4,5-C)pyridine derivatives as PD-L1 immunomodulators
|
UA126421C2
(uk)
|
2018-07-13 |
2022-09-28 |
Гіліад Сайєнсіз, Інк. |
Інгібітори pd-1/pd-l1
|
CN112424185B
(zh)
|
2018-07-13 |
2024-05-17 |
广州丹康医药生物有限公司 |
含苯环的化合物、其制备方法及应用
|