USRE47770E1
(en)
|
2002-07-18 |
2019-12-17 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
CN101537180B
(zh)
|
2002-07-18 |
2016-02-10 |
莫鲁斯有限公司 |
抗体混合物的重组生产
|
WO2006106905A1
(ja)
|
2005-03-31 |
2006-10-12 |
Chugai Seiyaku Kabushiki Kaisha |
会合制御によるポリペプチド製造方法
|
DK2009101T3
(en)
|
2006-03-31 |
2018-01-15 |
Chugai Pharmaceutical Co Ltd |
Antibody modification method for purification of a bispecific antibody
|
US11046784B2
(en)
|
2006-03-31 |
2021-06-29 |
Chugai Seiyaku Kabushiki Kaisha |
Methods for controlling blood pharmacokinetics of antibodies
|
ES2593484T3
(es)
|
2007-03-29 |
2016-12-09 |
Genmab A/S |
Anticuerpos biespecíficos y métodos de producción de los mismos
|
SI2202245T1
(sl)
|
2007-09-26 |
2016-10-28 |
Chugai Seiyaku Kabushiki Kaisha |
Postopek modificiranja izoelektrične točke protitelesa preko aminokislinske substitucije v CDR
|
MY163473A
(en)
|
2007-09-26 |
2017-09-15 |
Chugai Pharmaceutical Co Ltd |
Modified antibody constant region
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
PT2235064E
(pt)
*
|
2008-01-07 |
2016-03-01 |
Amgen Inc |
Método de preparação de moléculas heterodiméricas de fc de anticorpos utilizando efeitos de indução eletrostática
|
KR20220002710A
(ko)
|
2008-06-26 |
2022-01-06 |
악셀레론 파마 인코포레이티드 |
액티빈-actriia 길항물질을 투약하는 방법 및 치료된 환자의 모니터링
|
JP5787446B2
(ja)
|
2009-03-19 |
2015-09-30 |
中外製薬株式会社 |
抗体定常領域改変体
|
EP2417156B1
(en)
|
2009-04-07 |
2015-02-11 |
Roche Glycart AG |
Trivalent, bispecific antibodies
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
WO2011028952A1
(en)
*
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
CN104945509A
(zh)
|
2009-09-16 |
2015-09-30 |
弗·哈夫曼-拉罗切有限公司 |
包含卷曲螺旋和/或系链的蛋白质复合体及其用途
|
EP2543730B1
(en)
|
2010-03-04 |
2018-10-31 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody constant region variant
|
TW201138821A
(en)
|
2010-03-26 |
2011-11-16 |
Roche Glycart Ag |
Bispecific antibodies
|
US9150663B2
(en)
|
2010-04-20 |
2015-10-06 |
Genmab A/S |
Heterodimeric antibody Fc-containing proteins and methods for production thereof
|
EP2576621B1
(en)
|
2010-05-27 |
2019-04-10 |
Genmab A/S |
Monoclonal antibodies against her2
|
WO2012016227A2
(en)
|
2010-07-29 |
2012-02-02 |
Xencor, Inc. |
Antibodies with modified isoelectric points
|
AU2011288412A1
(en)
*
|
2010-08-13 |
2013-02-21 |
Medimmune Limited |
Monomeric polypeptides comprising variant Fc regions and methods of use
|
JP6167040B2
(ja)
|
2010-11-05 |
2017-07-19 |
ザイムワークス,インコーポレイテッド |
Fcドメイン中に突然変異を有する、安定したヘテロ二量体抗体の設計
|
CN105859889B
(zh)
|
2010-11-17 |
2020-01-07 |
中外制药株式会社 |
具有代替凝血因子viii的功能的功能的多特异性抗原结合分子
|
MX342034B
(es)
|
2011-02-28 |
2016-09-12 |
Hoffmann La Roche |
Proteinas monovalentes que se unen a antigenos.
|
BR112013019975A2
(pt)
|
2011-02-28 |
2017-08-01 |
Hoffmann La Roche |
proteínas de ligação de antígeno, composição farmacêutica, uso de uma proteína de ligação de antígeno, método para o tratamento de um paciente e método para a preparação de uma proteína de ligação de antígeno, ácido nucleico, vetor e célula hospedeira"
|
AU2012222833B2
(en)
|
2011-03-03 |
2017-03-16 |
Zymeworks Inc. |
Multivalent heteromultimer scaffold design and constructs
|
US20140112926A1
(en)
|
2011-03-16 |
2014-04-24 |
Amgen Inc. |
Fc VARIANTS
|
SG10201602371VA
(en)
|
2011-03-25 |
2016-04-28 |
Glenmark Pharmaceuticals Sa |
Hetero-dimeric immunoglobulins
|
JP5977814B2
(ja)
|
2011-04-08 |
2016-08-24 |
アムジエン・インコーポレーテツド |
増殖分化因子15(gdf−15)を使用して代謝障害を治療または改善する方法
|
WO2012143524A2
(en)
|
2011-04-20 |
2012-10-26 |
Genmab A/S |
Bispecific antibodies against her2 and cd3
|
DK2728002T3
(da)
*
|
2011-06-30 |
2022-04-04 |
Chugai Pharmaceutical Co Ltd |
Heterodimeriseret polypeptid
|
UA117901C2
(uk)
|
2011-07-06 |
2018-10-25 |
Ґенмаб Б.В. |
Спосіб посилення ефекторної функції вихідного поліпептиду, його варіанти та їх застосування
|
WO2013022855A1
(en)
*
|
2011-08-05 |
2013-02-14 |
Xencor, Inc. |
Antibodies with modified isoelectric points and immunofiltering
|
CN107586340B
(zh)
|
2011-08-23 |
2022-01-21 |
罗切格利卡特公司 |
对t细胞活化性抗原和肿瘤抗原特异性的双特异性抗体及使用方法
|
GB201116092D0
(en)
|
2011-09-16 |
2011-11-02 |
Bioceros B V |
Antibodies and uses thereof
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
DK2766392T3
(da)
*
|
2011-10-10 |
2019-10-07 |
Xencor Inc |
Fremgangsmåde til oprensning af antistoffer
|
PT2771364T
(pt)
|
2011-10-27 |
2019-09-10 |
Genmab As |
Produção de proteínas heterodiméricas
|
BR112014010257A2
(pt)
|
2011-10-31 |
2017-04-18 |
Chugai Pharmaceutical Co Ltd |
molécula de ligação ao antígeno tendo conjugação regulada entre cadeias pesadas e cadeias leves
|
PL2773671T3
(pl)
*
|
2011-11-04 |
2022-01-24 |
Zymeworks Inc. |
Projekt stabilnego przeciwciała heterodimerycznego z mutacjami w domenie fc
|
PL2782598T3
(pl)
|
2011-11-23 |
2021-03-08 |
In3Bio Ltd. |
Rekombinowane białka i ich zastosowania terapeutyczne
|
WO2013109994A1
(en)
|
2012-01-20 |
2013-07-25 |
Sea Lane Biotechnologies, Llc |
Surrobody cojugates
|
BR112014018575A2
(pt)
|
2012-01-26 |
2017-07-04 |
Amgen Inc |
polipetídeos de fator de diferenciação de crescimento 15 (gdf-15)
|
PT2838918T
(pt)
*
|
2012-04-20 |
2019-08-23 |
Merus Nv |
Métodos e meios para a produção de moléculas heterrodiméricas do tipo ig
|
US9090694B2
(en)
|
2012-04-30 |
2015-07-28 |
Janssen Biotech, Inc. |
ST2L antibody antagonists
|
WO2013166594A1
(en)
*
|
2012-05-10 |
2013-11-14 |
Zymeworks Inc. |
Heteromultimer constructs of immunoglobulin heavy chains with mutations in the fc domain
|
US20150125449A1
(en)
*
|
2012-05-10 |
2015-05-07 |
Zymeworks Inc. |
Single-Arm Monovalent Antibody Constructs and Uses Thereof
|
JP6628966B2
(ja)
|
2012-06-14 |
2020-01-15 |
中外製薬株式会社 |
改変されたFc領域を含む抗原結合分子
|
US9499634B2
(en)
|
2012-06-25 |
2016-11-22 |
Zymeworks Inc. |
Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells
|
EP3632462A1
(en)
|
2012-07-06 |
2020-04-08 |
Genmab B.V. |
Dimeric protein with triple mutations
|
BR112015000167B1
(pt)
|
2012-07-06 |
2021-11-23 |
Genmab B.V. |
Proteína dimérica, proteína, composição, kit de partes e seus usos, bem como método para aumentar a oligomerização em solução de uma proteína dimérica compreendendo um primeiro e segundo polipeptídeo, cada um compreendendo pelo menos as regiões ch2 e ch3 de uma cadeia pesada de igg1 humana e proteína dimérica variante
|
IN2015DN01115A
(pt)
|
2012-07-13 |
2015-06-26 |
Zymeworks Inc |
|
CN104640562A
(zh)
*
|
2012-07-13 |
2015-05-20 |
酵活有限公司 |
包含抗-cd3构建体的双特异性不对称异二聚体
|
US20140072581A1
(en)
*
|
2012-07-23 |
2014-03-13 |
Zymeworks Inc. |
Immunoglobulin Constructs Comprising Selective Pairing of the Light and Heavy Chains
|
KR20210084688A
(ko)
|
2012-08-24 |
2021-07-07 |
추가이 세이야쿠 가부시키가이샤 |
FcγRIIb 특이적 Fc영역 개변체
|
WO2014030750A1
(ja)
|
2012-08-24 |
2014-02-27 |
中外製薬株式会社 |
マウスFcγRII特異的Fc抗体
|
SI2900694T1
(sl)
|
2012-09-27 |
2018-12-31 |
Merus N.V. |
Bispecifična IGG protitelesa kot vključitelji T-celic
|
WO2014055784A1
(en)
|
2012-10-03 |
2014-04-10 |
Zymeworks Inc. |
Methods of quantitating heavy and light chain polypeptide pairs
|
EP2904016B1
(en)
|
2012-10-08 |
2018-11-14 |
Roche Glycart AG |
Fc-free antibodies comprising two fab-fragments and methods of use
|
EP2914634B1
(en)
|
2012-11-02 |
2017-12-06 |
Zymeworks Inc. |
Crystal structures of heterodimeric fc domains
|
CN112079929A
(zh)
*
|
2012-11-21 |
2020-12-15 |
武汉友芝友生物制药有限公司 |
双特异性抗体
|
SI2922872T1
(sl)
|
2012-11-21 |
2019-01-31 |
Janssen Biotech, Inc., |
Bispecifična protitelesa EGFR/C-MET
|
CN104955953B
(zh)
*
|
2012-11-27 |
2019-04-26 |
亚洲大学校产学协力团 |
高效诱导抗体重链恒定区的异源二聚体形成的ch3域变体对,其制备方法及用途
|
US9914785B2
(en)
|
2012-11-28 |
2018-03-13 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
CA2893562C
(en)
|
2012-11-28 |
2023-09-12 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
EP2940135B9
(en)
|
2012-12-27 |
2021-09-08 |
Chugai Seiyaku Kabushiki Kaisha |
Heterodimerized polypeptide
|
AU2013372331A1
(en)
|
2013-01-10 |
2015-07-23 |
Genmab B.V. |
Human IgG1 Fc region variants and uses thereof
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
EP3620473A1
(en)
*
|
2013-01-14 |
2020-03-11 |
Xencor, Inc. |
Novel heterodimeric proteins
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
AU2014207549B2
(en)
|
2013-01-15 |
2018-12-06 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
EP2954056A4
(en)
*
|
2013-02-08 |
2016-09-21 |
Stemcentrx Inc |
NEW MULTISPECIFIC CONSTRUCTIONS
|
EP3444278A1
(en)
|
2013-02-26 |
2019-02-20 |
Roche Glycart AG |
Bispecific t cell activating antigen binding molecules
|
CN104936986B
(zh)
|
2013-02-26 |
2019-08-09 |
罗切格利卡特公司 |
双特异性t细胞活化性抗原结合分子
|
US9902770B2
(en)
|
2013-03-15 |
2018-02-27 |
Janssen Biotech, Inc. |
Interferon alpha and omega antibody antagonists
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
CA2906927C
(en)
|
2013-03-15 |
2021-07-13 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
CA2902739C
(en)
|
2013-03-15 |
2022-11-22 |
Xencor, Inc. |
Heterodimeric proteins
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
HUE040234T2
(hu)
|
2013-03-18 |
2019-02-28 |
Biocerox Prod Bv |
Humanizált anti-CD134 (OX40) antitestek és felhasználásaik
|
EP3783017A1
(en)
|
2013-04-02 |
2021-02-24 |
Chugai Seiyaku Kabushiki Kaisha |
Fc region variant
|
EP2992011B1
(en)
|
2013-04-29 |
2017-12-13 |
F. Hoffmann-La Roche AG |
Fcrn-binding abolished anti-igf-1r antibodies and their use in the treatment of vascular eye diseases
|
SG10201800492PA
(en)
|
2013-04-29 |
2018-03-28 |
Hoffmann La Roche |
Human fcrn-binding modified antibodies and methods of use
|
PL2992010T3
(pl)
|
2013-04-29 |
2021-08-23 |
F.Hoffmann-La Roche Ag |
Modyfikowane asymetryczne przeciwciała wiążące receptor Fc i sposoby ich stosowania
|
WO2014182970A1
(en)
|
2013-05-08 |
2014-11-13 |
Zymeworks Inc. |
Bispecific her2 and her3 antigen binding constructs
|
RU2655439C2
(ru)
|
2013-05-31 |
2018-05-28 |
Займворкс Инк. |
Гетеромультимеры с уменьшенной или подавленной эффекторной функцией
|
KR102531517B1
(ko)
|
2013-07-05 |
2023-05-12 |
젠맵 에이/에스 |
인간화 또는 키메라 cd3 항체
|
BR112016000666A2
(pt)
*
|
2013-07-12 |
2017-10-03 |
Zymeworks Inc |
Constructos de ligação de antígeno cd3 e cd19 biespecíficos
|
KR102376451B1
(ko)
|
2013-07-31 |
2022-03-23 |
암젠 인크 |
성장 분화 인자 15(gdf-15) 작제물
|
BR112016006197B1
(pt)
*
|
2013-09-27 |
2023-04-11 |
Chugai Seiyaku Kabushiki Kaisha |
Método para produzir um anticorpo biespecífico de polipeptídeos
|
EP3055329B1
(en)
|
2013-10-11 |
2018-06-13 |
F. Hoffmann-La Roche AG |
Multispecific domain exchanged common variable light chain antibodies
|
RS62373B1
(sr)
|
2013-11-06 |
2021-10-29 |
Janssen Biotech Inc |
Anti-ccl17 antitela
|
CN113278076A
(zh)
|
2013-11-11 |
2021-08-20 |
中外制药株式会社 |
含有改变了抗体可变区的抗原结合分子
|
WO2015073721A1
(en)
*
|
2013-11-13 |
2015-05-21 |
Zymeworks Inc. |
Monovalent antigen binding constructs targeting egfr and/or her2 and uses thereof
|
MX2016006572A
(es)
|
2013-11-27 |
2016-12-09 |
Zymeworks Inc |
Construcciones de union a antigenos biespecificas dirigidas a her2.
|
UA120753C2
(uk)
|
2013-12-17 |
2020-02-10 |
Дженентек, Інк. |
Біспецифічне антитіло до сd3 та cd20
|
RS60031B1
(sr)
|
2013-12-20 |
2020-04-30 |
Hoffmann La Roche |
Humanizovana anti-tau(ps422) antitela i načini upotrebe
|
CN111228509A
(zh)
|
2014-01-03 |
2020-06-05 |
豪夫迈·罗氏有限公司 |
双特异性抗-半抗原/抗-血脑屏障受体的抗体、其复合物及其作为血脑屏障穿梭物的应用
|
CN111057147B
(zh)
|
2014-01-06 |
2023-11-10 |
豪夫迈·罗氏有限公司 |
单价血脑屏障穿梭模块
|
EP2891664A1
(en)
*
|
2014-01-07 |
2015-07-08 |
Technische Universität München |
Novel methods for the stabilisation of immunoglobulin constant domains
|
KR20160104636A
(ko)
|
2014-01-15 |
2016-09-05 |
에프. 호프만-라 로슈 아게 |
단백질 A-결합이 개선된 Fc-영역 변이체
|
CA2936785A1
(en)
*
|
2014-01-15 |
2015-07-23 |
Zymeworks Inc. |
Bi-specific cd3 and cd19 antigen-binding constructs
|
JP6786392B2
(ja)
|
2014-01-15 |
2020-11-18 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
FcRn結合特性が改変され、プロテインA結合特性が保持されているFc領域変異体
|
CN106459212B
(zh)
|
2014-02-28 |
2021-07-13 |
美勒斯公司 |
结合erbb-2和erbb-3的抗体
|
US9732154B2
(en)
|
2014-02-28 |
2017-08-15 |
Janssen Biotech, Inc. |
Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
|
CA2941030A1
(en)
|
2014-02-28 |
2015-09-03 |
Merus N.V. |
Antibodies that bind egfr and erbb3
|
ME03666B
(me)
|
2014-03-28 |
2020-10-20 |
Xencor Inc |
Bispecifična antitela koja se vezuju za cd38 i cd3
|
UA117289C2
(uk)
|
2014-04-02 |
2018-07-10 |
Ф. Хоффманн-Ля Рош Аг |
Мультиспецифічне антитіло
|
WO2015150446A1
(en)
|
2014-04-02 |
2015-10-08 |
F. Hoffmann-La Roche Ag |
Method for detecting multispecific antibody light chain mispairing
|
KR102568808B1
(ko)
|
2014-04-07 |
2023-08-18 |
추가이 세이야쿠 가부시키가이샤 |
면역활성화 항원 결합 분자
|
PL3137506T3
(pl)
|
2014-05-02 |
2024-02-26 |
Momenta Pharmaceuticals, Inc. |
Kompozycje i sposoby powiązane z uzyskanymi metodami inżynierii konstruktami fc
|
JP6894702B2
(ja)
|
2014-05-13 |
2021-06-30 |
中外製薬株式会社 |
免疫抑制機能を有する細胞に対するt細胞リダイレクト抗原結合分子
|
EP4026850A1
(en)
|
2014-05-28 |
2022-07-13 |
Zymeworks Inc. |
Modified antigen binding polypeptide constructs and uses thereof
|
WO2015187977A1
(en)
|
2014-06-04 |
2015-12-10 |
Acceleron Pharma, Inc. |
Methods and compositions for treatment of disorders with follistatin polypeptides
|
US10010498B2
(en)
|
2014-06-04 |
2018-07-03 |
Acceleron Pharma Inc. |
Methods for treatment of amyotrophic lateral sclerosis with follistatin fusion proteins
|
TWI713453B
(zh)
|
2014-06-23 |
2020-12-21 |
美商健生生物科技公司 |
干擾素α及ω抗體拮抗劑
|
AR100978A1
(es)
|
2014-06-26 |
2016-11-16 |
Hoffmann La Roche |
LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS
|
CN106687476B
(zh)
|
2014-06-26 |
2020-11-13 |
豪夫迈·罗氏有限公司 |
抗brdu抗体及使用方法
|
JP6701162B2
(ja)
|
2014-07-11 |
2020-05-27 |
ゲンマブ エー/エス |
Axlに結合する抗体
|
EP2982692A1
(en)
|
2014-08-04 |
2016-02-10 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
DK3177643T3
(da)
|
2014-08-04 |
2019-07-15 |
Hoffmann La Roche |
Bispecifikke T-celle-aktiverende antigenbindende molekyler
|
CA2959171C
(en)
|
2014-09-05 |
2023-11-14 |
Janssen Pharmaceutica Nv |
Cd123 binding agents and uses thereof
|
ES2890669T3
(es)
|
2014-09-09 |
2022-01-21 |
Janssen Biotech Inc |
Terapias de combinación con anticuerpos anti-CD38
|
AR101846A1
(es)
|
2014-09-12 |
2017-01-18 |
Genentech Inc |
Anticuerpos anti-cll-1 e inmunoconjugados
|
MA40764A
(fr)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
JP6708635B2
(ja)
|
2014-10-09 |
2020-06-10 |
エンクマフ エスアーエールエル |
CD3εおよびROR1に対する二特異性抗体
|
US11773166B2
(en)
|
2014-11-04 |
2023-10-03 |
Ichnos Sciences SA |
CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production
|
AR102522A1
(es)
|
2014-11-06 |
2017-03-08 |
Hoffmann La Roche |
Variantes de región fc con propiedades modificadas de unión a fcrn y proteína a
|
SI3215528T1
(sl)
|
2014-11-06 |
2019-11-29 |
Hoffmann La Roche |
Variante regije Fc s spremenjeno vezavo FcRn in postopki uporabe
|
TWI740809B
(zh)
|
2014-11-11 |
2021-10-01 |
日商中外製藥股份有限公司 |
包含經改變之抗體可變區之抗原結合分子的資料庫
|
EP3023437A1
(en)
|
2014-11-20 |
2016-05-25 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
EP4141032B1
(en)
|
2014-11-20 |
2024-05-29 |
F. Hoffmann-La Roche AG |
Combination therapy of t cell activating bispecific antigen binding molecules and pd-1 axis binding antagonists
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
KR20170084327A
(ko)
|
2014-11-26 |
2017-07-19 |
젠코어 인코포레이티드 |
Cd3 및 cd38에 결합하는 이형이량체 항체
|
EP3223845B1
(en)
|
2014-11-26 |
2021-05-19 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cd20
|
US20170355779A1
(en)
|
2014-11-27 |
2017-12-14 |
Zymeworks Inc. |
Methods of using bispecific antigen-binding constructs targeting her2
|
PL3227332T3
(pl)
|
2014-12-03 |
2020-06-15 |
F. Hoffmann-La Roche Ag |
Wielospecyficzne przeciwciała
|
DK3233907T3
(da)
|
2014-12-19 |
2021-06-07 |
Genmab As |
Bispecifikke heterodimeriske proteiner hos gnavere
|
WO2016105450A2
(en)
|
2014-12-22 |
2016-06-30 |
Xencor, Inc. |
Trispecific antibodies
|
MA41375A
(fr)
|
2015-01-22 |
2017-11-28 |
Lilly Co Eli |
Anticorps igg bispécifiques et leurs procédés de préparation
|
CN104610453A
(zh)
*
|
2015-01-23 |
2015-05-13 |
张帆 |
一类抗her2双靶向抗体、其制备方法及用途
|
WO2016141387A1
(en)
|
2015-03-05 |
2016-09-09 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
CA2980757A1
(en)
|
2015-03-26 |
2016-09-29 |
Acceleron Pharma Inc. |
Follistatin-related fusion proteins and uses thereof
|
WO2016159213A1
(ja)
|
2015-04-01 |
2016-10-06 |
中外製薬株式会社 |
ポリペプチド異種多量体の製造方法
|
KR20180002782A
(ko)
|
2015-05-06 |
2018-01-08 |
얀센 바이오테크 인코포레이티드 |
전립선 특이적 막 항원(psma) 이중특이성 결합제 및 그의 용도
|
EP3236996B1
(en)
|
2015-05-08 |
2022-03-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and tumor antigens
|
US10766965B2
(en)
|
2015-05-20 |
2020-09-08 |
Janssen Biotech, Inc. |
Anti-CD38 antibodies for treatment of light chain amyloidosis and other CD38-positive hematological malignancies
|
TWI773646B
(zh)
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
TW201718647A
(zh)
|
2015-06-16 |
2017-06-01 |
建南德克公司 |
抗-cll-1抗體及使用方法
|
CA2986928A1
(en)
|
2015-06-16 |
2016-12-22 |
Genentech, Inc. |
Humanized and affinity matured antibodies to fcrh5 and methods of use
|
CR20170587A
(es)
|
2015-06-22 |
2018-04-03 |
Janssen Biotech Inc |
Terapias de combinación para enfermedades malignas hematológicas con anticuerpos anti-cd38 e inhibidores de survivina
|
BR112017027990A2
(pt)
|
2015-06-24 |
2018-08-28 |
Janssen Biotech, Inc. |
modulação imune e tratamento de tumores sólidos com anticorpos que se ligam especificamente ao cd38
|
AR105089A1
(es)
|
2015-06-24 |
2017-09-06 |
Hoffmann La Roche |
ANTICUERPOS ANTI-TAU(pS422) HUMANIZADOS Y MÉTODOS DE UTILIZACIÓN
|
ES2784685T3
(es)
|
2015-07-10 |
2020-09-29 |
Genmab As |
Productos conjugados de anticuerpo-fármaco específicos de AXL para el tratamiento del cáncer
|
ES2812303T3
(es)
|
2015-07-10 |
2021-03-16 |
Merus Nv |
Anticuerpo que se une a CD3 humano
|
EP3322735A4
(en)
|
2015-07-15 |
2019-03-13 |
Zymeworks Inc. |
BISPECIFIC ANTIGEN-BINDING CONSTRUCTS CONJUGATED TO A MEDICINAL PRODUCT
|
US11359015B2
(en)
|
2015-07-15 |
2022-06-14 |
Genmab A/S |
Humanized or chimeric CD3 antibodies
|
IL256879B2
(en)
*
|
2015-07-24 |
2024-05-01 |
Gliknik Inc |
Fusion proteins of human protein fragments to create ordered multimeric immunoglobulin FC preparations with enhanced complement binding
|
MX2018001227A
(es)
|
2015-07-30 |
2018-03-26 |
Macrogenics Inc |
Moleculas de union a pd-1 y metodos de uso de las mismas.
|
CN107921128B
(zh)
|
2015-08-05 |
2022-04-26 |
詹森生物科技公司 |
抗cd154抗体及其使用方法
|
PL3337824T3
(pl)
|
2015-08-17 |
2021-04-19 |
Janssen Pharmaceutica Nv |
Przeciwciała anty-bcma, bispecyficzne cząsteczki wiążące antygen, które wiążą bcma i cd3, oraz ich zastosowania
|
AU2016329057A1
(en)
|
2015-09-30 |
2018-04-12 |
Janssen Biotech, Inc. |
Antagonistic antibodies specifically binding human CD40 and methods of use
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
WO2017055393A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xtim-3 bispecific t cell activating antigen binding molecules
|
CN108026179A
(zh)
|
2015-10-02 |
2018-05-11 |
豪夫迈·罗氏有限公司 |
结合间皮素和cd3的双特异性t细胞活化性抗原结合分子
|
EP3356821B1
(en)
|
2015-10-02 |
2019-10-23 |
H. Hoffnabb-La Roche Ag |
Cellular based fret assay for the determination of simultaneous binding
|
CR20180161A
(es)
|
2015-10-02 |
2018-05-25 |
Hoffmann La Roche |
Anticuerpos biespecíficos para pd1 y tim3
|
WO2017055385A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xgd2 bispecific t cell activating antigen binding molecules
|
WO2017055392A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xcd44v6 bispecific t cell activating antigen binding molecules
|
EP3150637A1
(en)
|
2015-10-02 |
2017-04-05 |
F. Hoffmann-La Roche AG |
Multispecific antibodies
|
MA43025A
(fr)
|
2015-10-02 |
2021-05-26 |
Hoffmann La Roche |
Molécules bispécifiques de liaison à l'antigène activant les lymphocytes t anti-ceaxcd3
|
JP6937746B2
(ja)
|
2015-10-02 |
2021-09-22 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
二重特異性抗cd19×cd3t細胞活性化抗原結合分子
|
US20180282410A1
(en)
|
2015-10-02 |
2018-10-04 |
Hoffmann-La Roche Inc. |
Anti-cd3xrob04 bispecific t cell activating antigen binding molecules
|
WO2017055388A2
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Bispecific t cell activating antigen binding molecules
|
CN108283001B
(zh)
|
2015-10-08 |
2022-08-19 |
酵活有限公司 |
包含κ和λ轻链的抗原结合多肽构建体及其用途
|
WO2017062619A2
(en)
|
2015-10-08 |
2017-04-13 |
Macrogenics, Inc. |
Combination therapy for the treatment of cancer
|
KR101851380B1
(ko)
*
|
2015-10-12 |
2018-04-23 |
아주대학교산학협력단 |
효모접합을 이용한 항체 ch3 도메인 이종이중체 돌연변이쌍 제조 방법 및 이에 의하여 제조된 ch3 돌연변이체 쌍
|
HUE055222T2
(hu)
|
2015-10-23 |
2021-11-29 |
Merus Nv |
Megkötõ molekulák, amelyek gátolják a rák növekedését
|
IL295756A
(en)
|
2015-10-29 |
2022-10-01 |
Hoffmann La Roche |
Antibodies against fc-variable region and methods of use
|
CA3003899A1
(en)
|
2015-11-02 |
2017-05-11 |
Janssen Pharmaceutica Nv |
Anti-il1rap antibodies, bispecific antigen binding molecules that bind il1rap and cd3, and uses thereof
|
US10894830B2
(en)
|
2015-11-03 |
2021-01-19 |
Janssen Biotech, Inc. |
Antibodies specifically binding PD-1, TIM-3 or PD-1 and TIM-3 and their uses
|
WO2017079150A1
(en)
|
2015-11-03 |
2017-05-11 |
Janssen Biotech, Inc. |
Subcutaneous formulations of anti-cd38 antibodies and their uses
|
JP6931329B2
(ja)
|
2015-11-18 |
2021-09-01 |
中外製薬株式会社 |
免疫抑制機能を有する細胞に対するt細胞リダイレクト抗原結合分子を用いた併用療法
|
WO2017086419A1
(ja)
|
2015-11-18 |
2017-05-26 |
中外製薬株式会社 |
液性免疫応答の増強方法
|
JP7058219B2
(ja)
|
2015-12-07 |
2022-04-21 |
ゼンコア インコーポレイテッド |
Cd3及びpsmaに結合するヘテロ二量体抗体
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
BR112018003984A2
(pt)
|
2015-12-09 |
2018-09-25 |
Hoffmann La Roche |
anticorpos
|
WO2017106061A1
(en)
|
2015-12-14 |
2017-06-22 |
Macrogenics, Inc. |
Bispecific molecules having immunoreactivity with pd-1 and ctla-4, and methods of use thereof
|
CN106883297B
(zh)
*
|
2015-12-16 |
2019-12-13 |
苏州康宁杰瑞生物科技有限公司 |
基于ch3结构域的异二聚体分子、其制备方法及用途
|
KR20180087430A
(ko)
|
2015-12-17 |
2018-08-01 |
얀센 바이오테크 인코포레이티드 |
Hla-dr에 특이적으로 결합하는 항체 및 이의 용도
|
EP3398965A4
(en)
|
2015-12-28 |
2019-09-18 |
Chugai Seiyaku Kabushiki Kaisha |
METHOD FOR PROMOTING THE EFFICACY OF PURIFYING A POLYPEPTIDE CONTAINING AN FC REGION
|
PL3400246T3
(pl)
|
2016-01-08 |
2021-03-08 |
F. Hoffmann-La Roche Ag |
Sposoby leczenia nowotworów z dodatnim markerem cea z wykorzystaniem antagonistów wiążących oś pd-1 oraz przeciwciał dwuswoistych anty-cea/anty-cd3
|
US20170233472A1
(en)
|
2016-02-17 |
2017-08-17 |
Macrogenics, Inc. |
ROR1-Binding Molecules, and Methods of Use Thereof
|
EP3431102A4
(en)
|
2016-03-14 |
2019-09-25 |
Chugai Seiyaku Kabushiki Kaisha |
THERAPEUTIC MEDICINE INDUCING CELLULAR INJURY FOR USE IN THE TREATMENT OF CANCER
|
US11291721B2
(en)
|
2016-03-21 |
2022-04-05 |
Marengo Therapeutics, Inc. |
Multispecific and multifunctional molecules and uses thereof
|
DK3433280T3
(da)
|
2016-03-22 |
2023-06-19 |
Hoffmann La Roche |
Protease-aktiverede T-celle-bispecifikke molekyler
|
MX2018012433A
(es)
|
2016-04-15 |
2019-03-01 |
Macrogenics Inc |
Moleculas de union b7-h3 novedosas, conjugados anticuerpo-farmaco de los mismos y metodos de uso de los mismos.
|
KR102523682B1
(ko)
|
2016-05-02 |
2023-04-19 |
에프. 호프만-라 로슈 아게 |
콘톨스바디 - 단쇄 표적 결합제
|
WO2017205436A1
(en)
|
2016-05-23 |
2017-11-30 |
Momenta Pharmaceuticals, Inc. |
Compositions and methods related to engineered fc constructs
|
WO2018220099A1
(en)
|
2017-06-02 |
2018-12-06 |
F. Hoffmann-La Roche Ag |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
CA3026420A1
(en)
|
2016-06-07 |
2017-12-14 |
Gliknik Inc. |
Cysteine-optimized stradomers
|
RU2022104399A
(ru)
|
2016-06-14 |
2022-05-05 |
Ксенкор, Инк. |
Биспецифические антитела-ингибиторы контрольных точек
|
US10316088B2
(en)
|
2016-06-28 |
2019-06-11 |
Xencor, Inc. |
Heterodimeric antibodies that bind somatostatin receptor 2
|
JP2019527678A
(ja)
|
2016-06-28 |
2019-10-03 |
ユーエムセー・ユトレヒト・ホールディング・ベー・フェー |
CD38に特異的に結合する抗体によるIgE媒介疾患の治療
|
CN109790526A
(zh)
|
2016-07-01 |
2019-05-21 |
分解治疗有限责任公司 |
优化的二核酸酶融合体和方法
|
CN109415435B
(zh)
|
2016-07-04 |
2024-01-16 |
豪夫迈·罗氏有限公司 |
新型抗体形式
|
EA201990293A1
(ru)
|
2016-07-14 |
2019-07-31 |
Генмаб А/С |
Мультиспецифичные антитела против cd40 и cd137
|
BR112019001138A2
(pt)
*
|
2016-07-19 |
2019-04-30 |
Ibentrus, Inc. |
proteínas biespecíficas e métodos para preparar as mesmas
|
TWI781108B
(zh)
|
2016-07-20 |
2022-10-21 |
比利時商健生藥品公司 |
抗gprc5d抗體、結合gprc5d與cd3之雙特異性抗原結合分子及其用途
|
WO2018026942A1
(en)
*
|
2016-08-02 |
2018-02-08 |
Merrimack Pharmaceuticals, Inc. |
Heteromeric polypeptides
|
US10696722B2
(en)
|
2016-08-10 |
2020-06-30 |
Ajou University Industry-Academic Cooperation Foundation |
Heterodimeric Fc-fused cytokine and pharmaceutical composition comprising the same
|
MA45941A
(fr)
|
2016-08-12 |
2019-06-19 |
Janssen Biotech Inc |
Anticorps de membres de la superfamille anti-tnfr modifiés par fc ayant une activité agoniste améliorée et leurs procédés d'utilisation
|
US10669344B2
(en)
|
2016-08-12 |
2020-06-02 |
Janssen Biotech, Inc. |
Engineered antibodies and other Fc-domain containing molecules with enhanced agonism and effector functions
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
WO2018045110A1
(en)
|
2016-08-30 |
2018-03-08 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
IL265605B1
(en)
|
2016-09-29 |
2024-02-01 |
Beijing Hanmi Pharmaceutical Co Ltd |
Heterodimeric immunoglobulin structures, a pharmaceutical preparation containing them, their use and methods for their preparation
|
CN109791149A
(zh)
|
2016-09-30 |
2019-05-21 |
豪夫迈·罗氏有限公司 |
用于功能分析多特异性分子的基于spr的双重结合测定法
|
WO2018060301A1
(en)
|
2016-09-30 |
2018-04-05 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies against cd3
|
CA3039545A1
(en)
*
|
2016-10-05 |
2018-04-12 |
Acceleron Pharma Inc. |
Tgf-beta superfamily type i and type ii receptor heteromultimers and uses thereof
|
KR102562519B1
(ko)
|
2016-10-14 |
2023-08-02 |
젠코어 인코포레이티드 |
IL-15/IL-15Rα FC-융합 단백질 및 PD-1 항체 단편을 포함하는 이중특이성 이종이량체 융합 단백질
|
JOP20190097A1
(ar)
|
2016-10-27 |
2019-04-28 |
Janssen Pharmaceutica Nv |
الجلوبولينات المناعية واستخداماتها
|
CN110461868A
(zh)
|
2016-11-01 |
2019-11-15 |
根马布私人有限公司 |
多肽变体及其用途
|
EP3541843A1
(en)
|
2016-11-15 |
2019-09-25 |
Genentech, Inc. |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies
|
CN109963876B
(zh)
|
2016-11-18 |
2023-11-14 |
北京韩美药品有限公司 |
抗pd-1/抗her2天然抗体结构样异源二聚体形式双特异抗体及其制备
|
TW201829463A
(zh)
|
2016-11-18 |
2018-08-16 |
瑞士商赫孚孟拉羅股份公司 |
抗hla-g抗體及其用途
|
CN110167591B
(zh)
|
2016-12-23 |
2023-09-26 |
宏观基因有限公司 |
Adam9结合分子及使用其的方法
|
BR112019013955A2
(pt)
|
2017-01-06 |
2020-02-11 |
Momenta Pharmaceuticals, Inc. |
Composições e métodos relacionados a construtos de fc manipulados
|
EP3565833A1
(en)
|
2017-01-09 |
2019-11-13 |
Torch Therapeutics |
Conditionally effective bispecific therapeutics
|
SG11201905259SA
(en)
*
|
2017-02-02 |
2019-08-27 |
Merck Patent Gmbh |
Preferred pairing of antibody domains
|
AU2018219887A1
(en)
|
2017-02-08 |
2019-08-22 |
Dragonfly Therapeutics, Inc. |
Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
|
CA3053222A1
(en)
|
2017-02-10 |
2018-08-16 |
Genmab B.V. |
Polypeptide variants and uses thereof
|
US20200291089A1
(en)
|
2017-02-16 |
2020-09-17 |
Elstar Therapeutics, Inc. |
Multifunctional molecules comprising a trimeric ligand and uses thereof
|
WO2018152326A1
(en)
|
2017-02-17 |
2018-08-23 |
Denali Therapeutics Inc. |
Engineered transferrin receptor binding polypeptides
|
ES2955074T3
(es)
|
2017-02-20 |
2023-11-28 |
Dragonfly Therapeutics Inc |
Proteínas que se unen a HER2, NKG2D Y CD16
|
WO2018155611A1
(ja)
|
2017-02-24 |
2018-08-30 |
中外製薬株式会社 |
薬学的組成物、抗原結合分子、治療方法、およびスクリーニング方法
|
MX2019010156A
(es)
*
|
2017-02-27 |
2020-01-09 |
Dragonfly Therapeutics Inc |
Proteínas multiespecíficas de unión de direccionamiento a anhidrasa carbónica 9 (caix), anoctamina-1 (ano1), mesotelina, antígeno de superficie celular de trofoblasto (trop2), antígeno carcinoembrionario (cea) o claudina-18.2.
|
EP3592769B1
(en)
|
2017-03-09 |
2024-05-08 |
Genmab A/S |
Antibodies against pd-l1
|
SG11201908127WA
(en)
|
2017-03-10 |
2019-10-30 |
Hoffmann La Roche |
Method for producing multispecific antibodies
|
EP3596108A4
(en)
|
2017-03-15 |
2020-12-23 |
Pandion Operations, Inc. |
TARGETED IMMUNOTOLERANCE
|
MX2019011660A
(es)
|
2017-03-31 |
2019-11-18 |
Merus Nv |
Anticuerpos biespecificos que se unen al receptor 2 del factor de crecimiento humano (erbb-2) y receptor 3 del factor de crecimiento humano (erbb3) para usarse en el tratamiento de celulas que tienen un gen de fusion de neuregulina-1 (nrg1).
|
EP3601354A1
(en)
|
2017-03-31 |
2020-02-05 |
Genmab Holding B.V. |
Bispecific anti-cd37 antibodies, monoclonal anti-cd37 antibodies and methods of use thereof
|
US11591409B2
(en)
*
|
2017-04-01 |
2023-02-28 |
Beijing Hanmi Pharm. Co., Ltd. |
Anti-PD-L1/anti-PD-1 natural antibody structure-like heterodimeric bispecific antibody and preparation thereof
|
EP3606947B1
(en)
|
2017-04-03 |
2022-12-21 |
F. Hoffmann-La Roche AG |
Immunoconjugates of il-2 with an anti-pd-1 and tim-3 bispecific antibody
|
CN110494452B
(zh)
|
2017-04-03 |
2023-08-25 |
豪夫迈·罗氏有限公司 |
结合steap-1的抗体
|
PL3606946T3
(pl)
|
2017-04-03 |
2022-11-28 |
F. Hoffmann-La Roche Ag |
Immunokoniugaty przeciwciała anty-PD-1 ze zmutowaną IL-2 lub z IL-15
|
BR112019019821A2
(pt)
|
2017-04-05 |
2020-04-22 |
Hoffmann La Roche |
anticorpo biespecífico, polinucleotídeo, célula hospedeira procariótica ou eucariótica, métodos de produção do anticorpo biespecífico, de tratamento de um indivíduo que tem câncer ou uma infecção viral crônica e de inibição do crescimento de células de tumor, composição farmacêutica e uso do anticorpo biespecífico
|
JOP20190222A1
(ar)
|
2017-04-11 |
2019-09-24 |
Zymeworks Inc |
الأجسام المضادة ثنائية النوعية المضادة لـ pd-l1 والمضادة لـ tim-3
|
AU2018250641A1
(en)
|
2017-04-11 |
2019-10-31 |
Inhibrx, Inc. |
Multispecific polypeptide constructs having constrained CD3 binding and methods of using the same
|
MX2019012187A
(es)
|
2017-04-13 |
2019-11-25 |
Hoffmann La Roche |
Un inmunoconjugado de interleuquina-2, un agonista de cd40 y opcionalmente un antagonista de union al eje pd-1 para uso en metodos para tratar cancer.
|
JP2020521452A
(ja)
|
2017-05-24 |
2020-07-27 |
パンディオン・セラピューティクス・インコーポレイテッド |
標的化免疫寛容
|
WO2018222901A1
(en)
|
2017-05-31 |
2018-12-06 |
Elstar Therapeutics, Inc. |
Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
|
KR20200014379A
(ko)
|
2017-06-05 |
2020-02-10 |
얀센 바이오테크 인코포레이티드 |
비대칭 ch2-ch3 영역 돌연변이를 갖는 조작된 다중특이성 항체 및 다른 다량체 단백질
|
KR20200014414A
(ko)
|
2017-06-05 |
2020-02-10 |
얀센 바이오테크 인코포레이티드 |
Pd-1과 특이적으로 결합하는 항체 및 사용 방법
|
EP3635005A1
(en)
|
2017-06-07 |
2020-04-15 |
Genmab B.V. |
Therapeutic antibodies based on mutated igg hexamers
|
JP7282383B2
(ja)
|
2017-06-14 |
2023-05-29 |
ディンフー バイオターゲット カンパニー リミテッド |
タンパク質性ヘテロ二量体及びその用途
|
CN110831978A
(zh)
|
2017-06-30 |
2020-02-21 |
酵活有限公司 |
稳定的嵌合fab
|
MA49517A
(fr)
|
2017-06-30 |
2020-05-06 |
Xencor Inc |
Protéines de fusion fc hétérodimères ciblées contenant il-15/il-15ra et domaines de liaison à l'antigène
|
AR112603A1
(es)
|
2017-07-10 |
2019-11-20 |
Lilly Co Eli |
Anticuerpos biespecíficos inhibidores de punto de control
|
BR112020001944A2
(pt)
|
2017-08-04 |
2020-08-04 |
Genmab A/S |
agente de ligação, ácido nucleico, vetor de expressão, célula, composição, métodos para tratamento de uma doença e para produção de um anticorpo biespecífico, uso de um agente de ligação, e, anticorpo anti-idiotípico.
|
CN111094351A
(zh)
|
2017-08-09 |
2020-05-01 |
美勒斯公司 |
结合EGFR和cMET的抗体
|
WO2019035938A1
(en)
|
2017-08-16 |
2019-02-21 |
Elstar Therapeutics, Inc. |
MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
|
WO2019040674A1
(en)
|
2017-08-22 |
2019-02-28 |
Sanabio, Llc |
SOLUBLE INTERFERON RECEPTORS AND USES THEREOF
|
JP7356726B2
(ja)
*
|
2017-09-25 |
2023-10-05 |
ディンフー バイオターゲット カンパニー リミテッド |
タンパク性ヘテロ二量体及びその使用
|
AU2018353420A1
(en)
|
2017-10-20 |
2020-04-16 |
F. Hoffmann-La Roche Ag |
Method for generating multispecific antibodies from monospecific antibodies
|
AU2018358883A1
(en)
|
2017-10-30 |
2020-04-23 |
F. Hoffmann-La Roche Ag |
Method for in vivo generation of multispecific antibodies from monospecific antibodies
|
KR102559706B1
(ko)
|
2017-11-01 |
2023-07-25 |
에프. 호프만-라 로슈 아게 |
Trifab-콘톨스바디
|
AU2018357923A1
(en)
|
2017-11-01 |
2020-03-05 |
F. Hoffmann-La Roche Ag |
Bispecific 2+1 contorsbodies
|
WO2019086394A1
(en)
|
2017-11-01 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
The compbody - a multivalent target binder
|
JP2021500902A
(ja)
|
2017-11-01 |
2021-01-14 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
新規tnfファミリーリガンド三量体含有抗原結合分子
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
KR20200085828A
(ko)
|
2017-11-08 |
2020-07-15 |
젠코어 인코포레이티드 |
신규의 항-pd-1 서열을 사용한 이중특이적 및 단일특이적 항체
|
JP7231641B2
(ja)
|
2017-12-04 |
2023-03-01 |
北京韓美薬品有限公司 |
天然抗体様構造を有し、ヘテロ二量体形態の抗pd-l1/抗cd47二重特異性抗体、ならびにその製造方法
|
JP7357616B2
(ja)
|
2017-12-05 |
2023-10-06 |
中外製薬株式会社 |
Cd3およびcd137に結合する改変された抗体可変領域を含む抗原結合分子
|
US10946068B2
(en)
|
2017-12-06 |
2021-03-16 |
Pandion Operations, Inc. |
IL-2 muteins and uses thereof
|
US10174092B1
(en)
|
2017-12-06 |
2019-01-08 |
Pandion Therapeutics, Inc. |
IL-2 muteins
|
SG11202005557TA
(en)
|
2017-12-12 |
2020-07-29 |
Macrogenics Inc |
Bispecific cd 16-binding molecules and their use in the treatment of disease
|
MX2020006322A
(es)
|
2017-12-19 |
2020-09-18 |
Xencor Inc |
Proteinas de fusion il-2 fc modificadas.
|
WO2019126401A1
(en)
|
2017-12-19 |
2019-06-27 |
Surrozen, Inc. |
Anti-lrp5/6 antibodies and methods of use
|
CN111727203B
(zh)
|
2017-12-19 |
2024-04-26 |
瑟罗泽恩奥普瑞汀公司 |
Wnt替代分子和其用途
|
BR112020011469A2
(pt)
|
2017-12-21 |
2020-11-24 |
F. Hoffmann-La Roche Ag |
anticorpos, molécula de ligação ao antígeno biespecífica, um ou mais polinucleotídeos isolados, um ou mais vetores, célula hospedeira, método para produzir um anticorpo, composição farmacêutica, uso do anticorpo, método de tratamento de uma doença e invenção
|
US11945839B2
(en)
|
2017-12-22 |
2024-04-02 |
Hoffmann-La Roche Inc. |
Depletion of light chain mispaired antibody variants by hydrophobic interaction chromatography
|
EP3732195A4
(en)
|
2017-12-28 |
2022-02-09 |
Chugai Seiyaku Kabushiki Kaisha |
CYTOTOXICITY-INDUCING THERAPEUTIC
|
MA51666A
(fr)
|
2018-01-24 |
2020-12-02 |
Genmab Bv |
Variants polypeptidiques et leurs utilisations
|
WO2019148412A1
(en)
|
2018-02-01 |
2019-08-08 |
Merck Sharp & Dohme Corp. |
Anti-pd-1/lag3 bispecific antibodies
|
EP3749359A1
(en)
|
2018-02-06 |
2020-12-16 |
F. Hoffmann-La Roche AG |
Treatment of ophthalmologic diseases
|
CA3089287A1
(en)
|
2018-02-08 |
2019-08-15 |
Genentech, Inc. |
Bispecific antigen-binding molecules and methods of use
|
BR112020016190A2
(pt)
|
2018-02-08 |
2020-12-15 |
Dragonfly Therapeutics, Inc. |
Domínios variáveis de anticorpos direcionando o receptor nkg2d
|
WO2019153200A1
(zh)
*
|
2018-02-08 |
2019-08-15 |
北京韩美药品有限公司 |
抗pd-1/抗her2天然抗体结构样异源二聚体形式双特异抗体及其制备
|
MA51747A
(fr)
|
2018-02-08 |
2020-12-16 |
Amgen Inc |
Formulation d'anticorps pharmaceutique à ph faible
|
TWI829667B
(zh)
|
2018-02-09 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
結合gprc5d之抗體
|
US11827697B2
(en)
|
2018-02-11 |
2023-11-28 |
Beijing Hanmi Pharmaceutical Co., Ltd. |
Anti-PD-1/anti-VEGF natural antibody structure like heterodimeric form bispecific antibody and preparation thereof
|
WO2019160007A1
(ja)
|
2018-02-14 |
2019-08-22 |
中外製薬株式会社 |
抗原結合分子および組合せ
|
US11685781B2
(en)
|
2018-02-15 |
2023-06-27 |
Macrogenics, Inc. |
Variant CD3-binding domains and their use in combination therapies for the treatment of disease
|
KR20200130723A
(ko)
|
2018-03-12 |
2020-11-19 |
젠맵 에이/에스 |
항체
|
HUE063489T2
(hu)
|
2018-03-13 |
2024-01-28 |
Zymeworks Bc Inc |
Anti-HER2 biparatopikus antitest-gyógyszer konjugátumok és alkalmazási módszereik
|
WO2019178364A2
(en)
|
2018-03-14 |
2019-09-19 |
Elstar Therapeutics, Inc. |
Multifunctional molecules and uses thereof
|
US20210238280A1
(en)
|
2018-03-14 |
2021-08-05 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
AU2019247415A1
(en)
|
2018-04-04 |
2020-10-22 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
CR20200510A
(es)
|
2018-04-09 |
2020-11-26 |
Amgen Inc |
Protreínas de fusión del factor de diferenciación de crecimiento 15
|
BR112020020604A2
(pt)
|
2018-04-11 |
2021-01-12 |
Inhibrx, Inc. |
Construções de polipeptídeo multiespecífico tendo ligação restrita de cd3 e métodos e usos relacionados
|
CA3097625A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Il-15/il-15ra heterodimeric fc fusion proteins and uses thereof
|
EP3781597A1
(en)
|
2018-04-18 |
2021-02-24 |
Xencor, Inc. |
Lag-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and lag-3 antigen binding domains
|
CN112437777A
(zh)
|
2018-04-18 |
2021-03-02 |
Xencor股份有限公司 |
包含IL-15/IL-15RA Fc融合蛋白和TIM-3抗原结合结构域的靶向TIM-3的异源二聚体融合蛋白
|
WO2019204665A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
AR115052A1
(es)
|
2018-04-18 |
2020-11-25 |
Hoffmann La Roche |
Anticuerpos multiespecíficos y utilización de los mismos
|
AU2019264217A1
(en)
|
2018-05-03 |
2020-12-17 |
Genmab B.V. |
Antibody variant combinations and uses thereof
|
US20200190205A1
(en)
|
2018-05-16 |
2020-06-18 |
Janssen Biotech, Inc. |
Methods of treating cancers and enhancing efficacy of t cell redirecting therapeutics
|
JOP20200302A1
(ar)
|
2018-05-24 |
2020-11-23 |
Janssen Biotech Inc |
الأجسام المضادة لـ cd3 واستخداماتها
|
PE20210634A1
(es)
|
2018-05-24 |
2021-03-23 |
Janssen Biotech Inc |
Anticuerpos anti-tmeff2 monoespecificos y multiespecificos y sus usos
|
JOP20190116A1
(ar)
|
2018-05-24 |
2019-11-24 |
Janssen Biotech Inc |
الأجسام المضادة لتكتل التمايز 33 (cd33)، والأجسام المضادة ثنائية النوعية لتكتل التمايز 33 (cd33)/تكتل التمايز 3 (cd3) واستخداماتها
|
JOP20200303A1
(ar)
|
2018-05-24 |
2020-11-23 |
Janssen Biotech Inc |
عوامل ربط psma واستخداماتها
|
SG11202011461TA
(en)
|
2018-06-01 |
2020-12-30 |
Compugen Ltd |
Anti-pvrig/anti-tigit bispecific antibodies and methods of use
|
CA3098420A1
(en)
|
2018-06-01 |
2019-12-05 |
Novartis Ag |
Binding molecules against bcma and uses thereof
|
TW202016144A
(zh)
|
2018-06-21 |
2020-05-01 |
日商第一三共股份有限公司 |
包括cd3抗原結合片段之組成物及其用途
|
US20210371539A1
(en)
|
2018-06-22 |
2021-12-02 |
Genmab Holding B.V. |
Anti-cd37 antibodies and anti-cd20 antibodies, compositions and methods of use thereof
|
JOP20200343A1
(ar)
|
2018-07-02 |
2020-12-31 |
Xencor Inc |
بروتين ربط مولد ضد مضاد لـ steap1
|
US11845797B2
(en)
|
2018-07-03 |
2023-12-19 |
Marengo Therapeutics, Inc. |
Anti-TCR antibody molecules and uses thereof
|
WO2020012038A1
(en)
|
2018-07-13 |
2020-01-16 |
Genmab A/S |
Trogocytosis-mediated therapy using cd38 antibodies
|
TW202019518A
(zh)
|
2018-07-13 |
2020-06-01 |
丹麥商珍美寶股份有限公司 |
Cd38抗體之變體及其用途
|
TW202019965A
(zh)
|
2018-07-16 |
2020-06-01 |
美商安進公司 |
治療多發性骨髓瘤之方法
|
JP2021531785A
(ja)
|
2018-07-24 |
2021-11-25 |
インヒブルクス インコーポレイテッド |
制約されたcd3結合ドメインおよび受容体結合領域を含有する多重特異性ポリペプチド構築物ならびにそれを使用する方法
|
JPWO2020045545A1
(ja)
|
2018-08-29 |
2021-08-12 |
中外製薬株式会社 |
抗体半分子、および抗体半分子のホモ二量体形成を抑制する方法
|
CA3115096A1
(en)
|
2018-10-03 |
2020-04-09 |
Xencor, Inc. |
Il-12 heterodimeric fc-fusion proteins
|
MX2021003756A
(es)
|
2018-10-04 |
2021-08-11 |
Genmab Holding B V |
Composiciones farmaceuticas que comprenden anticuerpos anti cumulo de diferenciacion 37 (cd37) biespecificos.
|
TW202028246A
(zh)
|
2018-10-11 |
2020-08-01 |
美商英伊布里克斯公司 |
B7h3單域抗體及其治療性組合物
|
WO2020076992A1
(en)
|
2018-10-11 |
2020-04-16 |
Inhibrx, Inc. |
5t4 single domain antibodies and therapeutic compositions thereof
|
EP3864049A1
(en)
|
2018-10-11 |
2021-08-18 |
Inhibrx, Inc. |
Pd-1 single domain antibodies and therapeutic compositions thereof
|
JP2022504822A
(ja)
|
2018-10-11 |
2022-01-13 |
インヒブルクス インコーポレイテッド |
Dll3シングルドメイン抗体およびその治療用組成物
|
BR112021006783A2
(pt)
|
2018-10-12 |
2021-07-13 |
Xencor, Inc. |
proteína de fusão fc heterodimérica de il-15/r¿ direcionada, composição de ácido nucleico, composição de vetor de expressão, célula hospedeira, e, métodos de produção da proteína de fusão fc heterodimérica de il-15/r¿ direcionada e de tratamento de um câncer.
|
US20220119533A1
(en)
|
2018-10-23 |
2022-04-21 |
Dragonfly Therapeutics, Inc. |
Heterodimeric fc-fused proteins
|
PE20211865A1
(es)
|
2018-10-29 |
2021-09-21 |
Hoffmann La Roche |
Formulacion de anticuerpos
|
JP2022506411A
(ja)
*
|
2018-11-05 |
2022-01-17 |
北京韓美薬品有限公司 |
抗TNFα/抗IL-17A天然抗体構造様ヘテロダイマー二重特異性抗体及びその製造方法
|
CA3118789A1
(en)
|
2018-11-06 |
2020-05-14 |
Genmab A/S |
Antibody formulation
|
US20220041719A1
(en)
|
2018-12-05 |
2022-02-10 |
Morphosys Ag |
Multispecific antigen-binding molecules
|
CN113438961A
(zh)
|
2018-12-20 |
2021-09-24 |
Xencor股份有限公司 |
含有IL-15/IL-15Rα和NKG2D抗原结合结构域的靶向异二聚体Fc融合蛋白
|
CN113621062A
(zh)
|
2018-12-21 |
2021-11-09 |
豪夫迈·罗氏有限公司 |
与cd3结合的抗体
|
TW202041534A
(zh)
|
2018-12-24 |
2020-11-16 |
法商賽諾菲公司 |
基於假Fab的多特異性結合蛋白
|
WO2020136060A1
(en)
|
2018-12-28 |
2020-07-02 |
F. Hoffmann-La Roche Ag |
A peptide-mhc-i-antibody fusion protein for therapeutic use in a patient with amplified immune response
|
SG11202106686PA
(en)
|
2019-01-04 |
2021-07-29 |
Resolve Therapeutics Llc |
Treatment of sjogren's disease with nuclease fusion proteins
|
TW202043256A
(zh)
|
2019-01-10 |
2020-12-01 |
美商健生生物科技公司 |
***新抗原及其用途
|
CN113574066A
(zh)
|
2019-01-15 |
2021-10-29 |
詹森生物科技公司 |
用于治疗幼年特发性关节炎的抗tnf抗体组合物和方法
|
EP3911677A1
(en)
|
2019-01-18 |
2021-11-24 |
Janssen Biotech, Inc. |
Gprc5d chimeric antigen receptors and cells expressing the same
|
EA202192038A1
(ru)
|
2019-01-23 |
2021-10-05 |
Янссен Байотек, Инк. |
Композиции антител к фно для применения в способах лечения псориатического артрита
|
EP3927744A1
(en)
|
2019-02-21 |
2021-12-29 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to t cell related cancer cells and uses thereof
|
CA3130508A1
(en)
|
2019-02-21 |
2020-08-27 |
Marengo Therapeutics, Inc. |
Antibody molecules that bind to nkp30 and uses thereof
|
CN114127113A
(zh)
|
2019-02-21 |
2022-03-01 |
马伦戈治疗公司 |
与钙网蛋白结合的多功能分子及其用途
|
SG11202109033XA
(en)
|
2019-02-21 |
2021-09-29 |
Marengo Therapeutics Inc |
Multifunctional molecules that bind to t cells and uses thereof to treat autoimmune disorders
|
WO2020172631A2
(en)
|
2019-02-21 |
2020-08-27 |
Xencor, Inc. |
Untargeted and targeted il-10 fc-fusion proteins
|
SG11202109122SA
(en)
|
2019-02-21 |
2021-09-29 |
Marengo Therapeutics Inc |
Anti-tcr antibody molecules and uses thereof
|
KR20210132117A
(ko)
|
2019-02-26 |
2021-11-03 |
얀센 바이오테크 인코포레이티드 |
이중특이성 항-EGFR/c-Met 항체를 사용한 병용 요법 및 환자 계층화
|
US11472890B2
(en)
|
2019-03-01 |
2022-10-18 |
Xencor, Inc. |
Heterodimeric antibodies that bind ENPP3 and CD3
|
KR20210138033A
(ko)
|
2019-03-11 |
2021-11-18 |
얀센 바이오테크 인코포레이티드 |
항-Vβ17/항-CD123 이중특이성 항체
|
EP3938384A4
(en)
|
2019-03-14 |
2022-12-28 |
Janssen Biotech, Inc. |
METHODS OF MANUFACTURING FOR PRODUCING ANTI-IL12/IL23 ANTIBODY COMPOSITIONS
|
JP2022524860A
(ja)
|
2019-03-14 |
2022-05-10 |
ヤンセン バイオテツク,インコーポレーテツド |
抗tnf抗体組成物を産生するための方法
|
US20220144934A1
(en)
|
2019-03-14 |
2022-05-12 |
Janssen Biotech, Inc. |
Methods for Producing Anti-TNF Antibody Compositions
|
US20220153830A1
(en)
|
2019-03-14 |
2022-05-19 |
Janssen Biotech, Inc. |
Manufacturing Methods for Producing Anti-TNF Antibody Compositions
|
EP3946354A4
(en)
*
|
2019-03-28 |
2023-01-11 |
Ab Studio Inc. |
HETEROMULTIMER PROTEINS AND METHODS OF USE THEREOF
|
WO2020200941A1
(en)
|
2019-03-29 |
2020-10-08 |
F. Hoffmann-La Roche Ag |
Spr-based binding assay for the functional analysis of multivalent molecules
|
WO2020200944A1
(en)
|
2019-03-29 |
2020-10-08 |
F. Hoffmann-La Roche Ag |
Method for generating avid-binding multispecific antibodies
|
AU2020263910A1
(en)
|
2019-04-25 |
2021-10-21 |
F. Hoffmann-La Roche Ag |
Activatable therapeutic multispecific polypeptides with extended half-life
|
CA3132494A1
(en)
|
2019-04-25 |
2020-10-29 |
Ulrich Brinkmann |
Therapeutic multispecific polypeptides activated by polypeptide chain exchange
|
WO2020216878A1
(en)
|
2019-04-25 |
2020-10-29 |
F. Hoffmann-La Roche Ag |
Generation of antibody-derived polypeptides by polypeptide chain exchange
|
CR20210548A
(es)
|
2019-05-08 |
2022-02-11 |
Janssen Biotech Inc |
Materiales y métodos para modular la inmunidad mediada por células t
|
WO2020225456A1
(en)
|
2019-05-09 |
2020-11-12 |
Genmab B.V. |
Dosage regimens for a combination of anti-dr5 antibodies for use in treating cancer
|
WO2020229378A1
(en)
|
2019-05-13 |
2020-11-19 |
F. Hoffmann-La Roche Ag |
Interference-suppressed pharmacokinetic immunoassay
|
WO2020230091A1
(en)
|
2019-05-14 |
2020-11-19 |
Janssen Biotech, Inc. |
Combination therapies with bispecific anti-egfr/c-met antibodies and third generation egfr tyrosine kinase inhibitors
|
KR20220080221A
(ko)
*
|
2019-05-14 |
2022-06-14 |
주식회사 프로젠 |
신규 변형 면역글로불린 fc 융합단백질 및 그의 용도
|
CN114080397A
(zh)
|
2019-05-17 |
2022-02-22 |
Xencor股份有限公司 |
Il-7-fc融合蛋白
|
AU2020279240A1
(en)
|
2019-05-20 |
2021-12-23 |
Pandion Operations, Inc. |
MAdCAM targeted immunotolerance
|
WO2020236795A2
(en)
|
2019-05-21 |
2020-11-26 |
Novartis Ag |
Trispecific binding molecules against bcma and uses thereof
|
EP3972993A1
(en)
|
2019-05-21 |
2022-03-30 |
Novartis AG |
Variant cd58 domains and uses thereof
|
PE20220568A1
(es)
|
2019-05-21 |
2022-04-20 |
Novartis Ag |
Moleculas de union a cd19 y usos de las mismas
|
CA3142665A1
(en)
|
2019-06-03 |
2020-12-10 |
Janssen Biotech, Inc. |
Anti-tnf antibody compositions, and methods for the treatment of psoriatic arthritis
|
JPWO2020246563A1
(pt)
|
2019-06-05 |
2020-12-10 |
|
|
AU2020294880B2
(en)
|
2019-06-19 |
2024-05-02 |
F. Hoffmann-La Roche Ag |
Method for the generation of a protein expressing cell by targeted integration using Cre mRNA
|
CN114026224B
(zh)
|
2019-06-26 |
2024-03-15 |
豪夫迈·罗氏有限公司 |
具有sirt-1基因敲除的哺乳动物细胞系
|
US20220380478A1
(en)
|
2019-07-01 |
2022-12-01 |
Tonix Pharma Holdings Limited |
Anti-cd154 antibodies and uses thereof
|
CN114051500A
(zh)
|
2019-07-02 |
2022-02-15 |
豪夫迈·罗氏有限公司 |
包含白细胞介素-2突变体和抗cd8抗体的免疫缀合物
|
BR112021023173A2
(pt)
|
2019-07-10 |
2022-01-04 |
Chugai Pharmaceutical Co Ltd |
Moléculas de ligação à claudin-6 e usos das mesmas
|
CN112210005B
(zh)
*
|
2019-07-11 |
2024-03-26 |
京天成生物技术(北京)有限公司 |
低免疫原性低adcc/cdc功能的抗c5人源化单抗及其应用
|
BR112022000145A2
(pt)
|
2019-07-12 |
2022-02-22 |
Janssen Pharmaceutica Nv |
Agentes de ligação e usos dos mesmos
|
AR119393A1
(es)
|
2019-07-15 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos que se unen a nkg2d
|
JP2022541332A
(ja)
|
2019-07-26 |
2022-09-22 |
ヤンセン バイオテツク,インコーポレーテツド |
カリクレイン関連ペプチダーゼ2抗原結合ドメインを含むタンパク質及びその使用
|
CN114174338A
(zh)
|
2019-07-31 |
2022-03-11 |
豪夫迈·罗氏有限公司 |
与gprc5d结合的抗体
|
CR20220019A
(es)
|
2019-07-31 |
2022-02-11 |
Hoffmann La Roche |
Anticuerpos que se fijan a gprc5d
|
US20210102002A1
(en)
|
2019-08-06 |
2021-04-08 |
Xencor, Inc. |
HETERODIMERIC IgG-LIKE BISPECIFIC ANTIBODIES
|
JOP20220035A1
(ar)
|
2019-08-15 |
2023-01-30 |
Janssen Biotech Inc |
مواد وطرق لتحسين أجزاء المتغير أحادي السلسلة
|
CN115916233A
(zh)
|
2019-10-03 |
2023-04-04 |
Xencor股份有限公司 |
靶向IL-12异源二聚体Fc融合蛋白
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
EP4055046A1
(en)
|
2019-11-06 |
2022-09-14 |
Genmab B.V. |
Antibody variant combinations and uses thereof
|
MX2022005983A
(es)
|
2019-11-18 |
2022-09-07 |
Janssen Biotech Inc |
Receptores del antígeno quimérico anti-cd79, células car-t, y usos de estos.
|
EP4073111A1
(en)
|
2019-12-11 |
2022-10-19 |
Cilag GmbH International |
Multispecific binding molecules comprising ltbr and edb binding domains and uses thereof
|
WO2021119505A1
(en)
|
2019-12-13 |
2021-06-17 |
Genentech, Inc. |
Anti-ly6g6d antibodies and methods of use
|
AU2020406083A1
(en)
|
2019-12-17 |
2022-06-16 |
Ose Immunotherapeutics |
Bifunctional molecules comprising an IL-7 variant
|
BR112022011854A2
(pt)
|
2019-12-18 |
2022-09-06 |
Hoffmann La Roche |
Anticorpos, polinucleotídeo isolado, célula hospedeira, métodos para produzir um anticorpo e para tratar uma doença, composição farmacêutica, usos do anticorpo e invenção
|
JP7415005B2
(ja)
|
2019-12-18 |
2024-01-16 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
二重特異性抗ccl2抗体
|
GB201919061D0
(en)
|
2019-12-20 |
2020-02-05 |
Ucb Biopharma Sprl |
Multi-specific antibody
|
GB201919062D0
(en)
|
2019-12-20 |
2020-02-05 |
Ucb Biopharma Sprl |
Antibody
|
US20230046416A1
(en)
|
2019-12-23 |
2023-02-16 |
Soteria Biotherapeutics, Inc. |
Chemically Induced Association and Dissociation of Therapeutic FC Compositions and Chemically Induced Dimerization of T Cell Engager with Human Serum Albumin
|
IL294226A
(en)
|
2019-12-27 |
2022-08-01 |
Chugai Pharmaceutical Co Ltd |
Anti-ctla-4 antibodies and their use
|
US11913945B2
(en)
|
2020-01-02 |
2024-02-27 |
Hoffmann-La Roche Inc. |
Method for determining the amount of a therapeutic antibody in the brain
|
EP4084821A4
(en)
|
2020-01-03 |
2024-04-24 |
Marengo Therapeutics Inc |
CD33-BINDING MULTIFUNCTIONAL MOLECULES AND THEIR USES
|
KR20220130724A
(ko)
|
2020-01-16 |
2022-09-27 |
젠맵 에이/에스 |
Cd38 항체의 제제 및 그의 용도
|
EP4097129A1
(en)
|
2020-01-29 |
2022-12-07 |
Inhibrx, Inc. |
Cd28 single domain antibodies and multivalent and multispecific constructs thereof
|
WO2021154839A1
(en)
|
2020-01-30 |
2021-08-05 |
Umoja Biopharma, Inc. |
Bispecific transduction enhancer
|
GB202001447D0
(en)
|
2020-02-03 |
2020-03-18 |
Ucb Biopharma Sprl |
Antibodies
|
WO2021155916A1
(en)
|
2020-02-04 |
2021-08-12 |
BioNTech SE |
Treatment involving antigen vaccination and binding agents binding to pd-l1 and cd137
|
TW202144389A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在多發性骨髓瘤中表現之新抗原及其用途
|
TW202144388A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在卵巢癌中表現之新抗原及其用途
|
EP4107187A1
(en)
|
2020-02-21 |
2022-12-28 |
Pandion Operations, Inc. |
Tissue targeted immunotolerance with a cd39 effector
|
KR20230051617A
(ko)
|
2020-03-13 |
2023-04-18 |
얀센 바이오테크 인코포레이티드 |
Siglec-3/cd33을 결합시키기 위한 물질 및 방법
|
EP4121456A1
(en)
|
2020-03-18 |
2023-01-25 |
Genmab A/S |
Antibodies binding to b7h4
|
WO2021195513A1
(en)
|
2020-03-27 |
2021-09-30 |
Novartis Ag |
Bispecific combination therapy for treating proliferative diseases and autoimmune disorders
|
US20230121511A1
(en)
|
2020-03-31 |
2023-04-20 |
Chugai Seiyaku Kabushiki Kaisha |
Method for producing multispecific antigen-binding molecules
|
TWI799824B
(zh)
|
2020-03-31 |
2023-04-21 |
日商中外製藥股份有限公司 |
Dll3靶向之多特異性抗原結合分子及其用途
|
AU2021256936A1
(en)
|
2020-04-15 |
2022-07-21 |
F. Hoffmann-La Roche Ag |
Immunoconjugates
|
US20230138852A1
(en)
|
2020-04-16 |
2023-05-04 |
Janssen Biotech, Inc. |
Systems, materials, and methods for reversed-phase high performance liquid chromatography (rp-hplc) identification of multi-specific molecules
|
GB202005879D0
(en)
*
|
2020-04-22 |
2020-06-03 |
Petmedix Ltd |
Heterodimeric proteins
|
AU2021261420A1
(en)
|
2020-04-24 |
2022-12-01 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to T cell related cancer cells and uses thereof
|
CA3180173A1
(en)
|
2020-04-30 |
2021-11-04 |
Bristol-Myers Squibb Company |
Methods of treating cytokine-related adverse events
|
IL298046A
(en)
|
2020-05-11 |
2023-01-01 |
Janssen Biotech Inc |
Treatment methods for multiple myeloma
|
CN115551540A
(zh)
|
2020-05-11 |
2022-12-30 |
豪夫迈·罗氏有限公司 |
使用经修饰的pbmc和免疫缀合物的组合疗法
|
EP4149632A1
(en)
|
2020-05-14 |
2023-03-22 |
Xencor, Inc. |
Heterodimeric antibodies that bind msln and cd3
|
US11919956B2
(en)
|
2020-05-14 |
2024-03-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (PSMA) and CD3
|
MX2022014938A
(es)
|
2020-05-27 |
2023-03-06 |
Janssen Biotech Inc |
Proteínas que comprenden dominios de unión al antígeno de cd3 y usos de éstas.
|
AU2021290997C1
(en)
*
|
2020-06-17 |
2024-01-04 |
Medimmune Limited |
Heterodimeric relaxin fusions and uses thereof
|
WO2021255146A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3 and cea
|
TW202219065A
(zh)
|
2020-06-19 |
2022-05-16 |
瑞士商赫孚孟拉羅股份公司 |
免疫活化 Fc 域結合分子
|
KR20230025673A
(ko)
|
2020-06-19 |
2023-02-22 |
에프. 호프만-라 로슈 아게 |
CD3 및 FolR1에 결합하는 항체
|
MX2022016069A
(es)
|
2020-06-19 |
2023-02-02 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y cd19.
|
CA3176579A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3
|
US20230355722A1
(en)
|
2020-06-29 |
2023-11-09 |
Resolve Therapeutics, Llc |
Treatment of sjogren’s syndrome with nuclease fusion proteins
|
EP4185388A1
(en)
|
2020-07-23 |
2023-05-31 |
Genmab B.V. |
A combination of anti-dr5 antibodies and an immunomodulatory imide drug for use in treating multiple myeloma
|
CA3190307A1
(en)
|
2020-07-29 |
2022-02-03 |
Janssen Biotech, Inc. |
Proteins comprising hla-g antigen binding domains and their uses
|
CN116194124A
(zh)
|
2020-07-31 |
2023-05-30 |
中外制药株式会社 |
包含表达嵌合受体的细胞的药物组合物
|
AU2021322046A1
(en)
|
2020-08-06 |
2023-02-02 |
BioNTech SE |
Binding agents for coronavirus S protein
|
EP4200332A1
(en)
|
2020-08-19 |
2023-06-28 |
Xencor, Inc. |
Anti-cd28 and/or anti-b7h3 compositions
|
CA3190755A1
(en)
|
2020-08-26 |
2022-03-03 |
Andreas Loew |
Multifunctional molecules that bind to calreticulin and uses thereof
|
AU2021333779A1
(en)
|
2020-08-26 |
2023-04-13 |
Marengo Therapeutics, Inc. |
Methods of detecting TRBC1 or TRBC2
|
KR20230074144A
(ko)
|
2020-08-26 |
2023-05-26 |
마렝고 테라퓨틱스, 인크. |
NKp30에 결합하는 항체 분자 및 이의 용도
|
JPWO2022044248A1
(pt)
*
|
2020-08-28 |
2022-03-03 |
|
|
US20230310599A1
(en)
|
2020-09-02 |
2023-10-05 |
Genmab A/S |
Antibody therapy
|
CN116437956A
(zh)
|
2020-09-10 |
2023-07-14 |
健玛保 |
用于治疗慢性淋巴细胞白血病的针对cd3和cd20的双特异性抗体
|
KR20230066583A
(ko)
|
2020-09-10 |
2023-05-16 |
젠맵 에이/에스 |
미만성 대 b-세포 림프종을 치료하기 위한 조합 요법에서의 cd3 및 cd20에 대한 이중특이적 항체
|
KR20230084508A
(ko)
|
2020-09-11 |
2023-06-13 |
얀센 바이오테크 인코포레이티드 |
베타 사슬 매개 면역을 조절하기 위한 방법 및 조성물
|
CN116391037A
(zh)
|
2020-09-24 |
2023-07-04 |
豪夫迈·罗氏有限公司 |
具有基因敲除的哺乳动物细胞系
|
EP4221742A1
(en)
|
2020-10-02 |
2023-08-09 |
Genmab A/S |
Antibodies capable of binding to ror2 and bispecific antibodies binding to ror2 and cd3
|
AR123767A1
(es)
|
2020-10-13 |
2023-01-11 |
Janssen Biotech Inc |
Inmunidad mediada por células t mediante bioingeniería, materiales y otros métodos para modular el cúmulo de diferenciación iv y/o viii
|
WO2022081886A1
(en)
|
2020-10-14 |
2022-04-21 |
Xencor, Inc. |
Bispecific antibodies that bind pd-l1 and cd28
|
WO2022084915A1
(en)
|
2020-10-22 |
2022-04-28 |
Janssen Biotech, Inc. |
Proteins comprising delta-like ligand 3 (dll3) antigen binding domains and their uses
|
WO2022099090A1
(en)
|
2020-11-06 |
2022-05-12 |
Xencor, Inc. |
Heterodimeric antibodies that bind tgfbrii
|
EP4240491A1
(en)
|
2020-11-06 |
2023-09-13 |
Novartis AG |
Cd19 binding molecules and uses thereof
|
IL302412A
(en)
|
2020-11-06 |
2023-06-01 |
Novartis Ag |
Anti-CD19 and B-cell targeting agent combination therapy for the treatment of B-cell malignancies
|
CN117120477A
(zh)
|
2020-11-10 |
2023-11-24 |
上海齐鲁制药研究中心有限公司 |
针对密蛋白18a2和cd3的双特异性抗体及其应用
|
AU2021392318A1
(en)
*
|
2020-12-03 |
2023-07-20 |
Zymeworks Bc Inc. |
Heterodimeric iga fc constructs and methods of use thereof
|
WO2022122652A1
(en)
|
2020-12-07 |
2022-06-16 |
UCB Biopharma SRL |
Antibodies against interleukin-22
|
MX2023006650A
(es)
|
2020-12-07 |
2023-06-21 |
UCB Biopharma SRL |
Anticuerpos multiespecificos y combinaciones de anticuerpos.
|
CA3201729A1
(en)
|
2020-12-17 |
2022-06-23 |
Nicolas Poirier |
Bifunctional anti-pd1/il-7 molecules
|
US20220213199A1
(en)
|
2020-12-17 |
2022-07-07 |
Hoffmann-La Roche Inc. |
Anti-HLA-G antibodies and use thereof
|
EP4263595A1
(en)
|
2020-12-18 |
2023-10-25 |
F. Hoffmann-La Roche AG |
Precursor proteins and kit for targeted therapy
|
CN116670282A
(zh)
|
2020-12-22 |
2023-08-29 |
豪夫迈·罗氏有限公司 |
靶向xbp1的寡核苷酸
|
US20220227867A1
(en)
|
2020-12-24 |
2022-07-21 |
Xencor, Inc. |
ICOS TARGETED HETERODIMERIC FUSION PROTEINS CONTAINING IL-15/IL-15RA Fc-FUSION PROTEINS AND ICOS ANTIGEN BINDING DOMAINS
|
TWI825544B
(zh)
*
|
2020-12-31 |
2023-12-11 |
大陸商信達生物製藥(蘇州)有限公司 |
含異二聚體抗體Fc的蛋白以及其製備方法
|
CN116829598A
(zh)
|
2021-01-06 |
2023-09-29 |
豪夫迈·罗氏有限公司 |
采用pd1-lag3双特异性抗体和cd20 t细胞双特异性抗体的组合疗法
|
EP4274587A1
(en)
|
2021-01-06 |
2023-11-15 |
Tonix Pharma Limited |
Methods of inducing immune tolerance with modified anti-cd154 antibodies
|
WO2022148853A1
(en)
|
2021-01-11 |
2022-07-14 |
F. Hoffmann-La Roche Ag |
Immunoconjugates
|
AU2022214491A1
(en)
|
2021-01-28 |
2023-09-14 |
Janssen Biotech, Inc. |
Psma binding proteins and uses thereof
|
JP2024506694A
(ja)
|
2021-02-16 |
2024-02-14 |
ヤンセン バイオテツク,インコーポレーテツド |
増強されたリンカー標的化のための材料及び方法
|
CN117279953A
(zh)
|
2021-02-16 |
2023-12-22 |
詹森药业有限公司 |
靶向bcma、gprc5d和cd3的三特异性抗体
|
EP4295154A1
(en)
|
2021-02-18 |
2023-12-27 |
F. Hoffmann-La Roche AG |
Method for resolving complex, multistep antibody interactions
|
CA3212665A1
(en)
|
2021-03-09 |
2022-09-15 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cldn6
|
JP2024509920A
(ja)
|
2021-03-09 |
2024-03-05 |
ヤンセン バイオテツク,インコーポレーテツド |
Egfr活性化変異を欠くがんの治療
|
WO2022192586A1
(en)
|
2021-03-10 |
2022-09-15 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and gpc3
|
KR20230156921A
(ko)
|
2021-03-12 |
2023-11-15 |
젠맵 에이/에스 |
비-활성화 항체 변이체
|
IL306132A
(en)
|
2021-03-24 |
2023-11-01 |
Janssen Biotech Inc |
Proteins containing CD3 antigen binding sites and uses thereof
|
AU2022244114A1
(en)
|
2021-03-24 |
2023-11-09 |
Janssen Biotech, Inc. |
TRISPECIFIC ANTIBODY TARGETING CD79b, CD20, AND CD3
|
AU2022244453A1
(en)
|
2021-03-24 |
2023-11-09 |
Janssen Biotech, Inc. |
Antibody targeting cd22 and cd79b
|
WO2022206872A1
(zh)
|
2021-03-31 |
2022-10-06 |
江苏恒瑞医药股份有限公司 |
截短的taci多肽及其融合蛋白和用途
|
GB2623199A
(en)
|
2021-04-08 |
2024-04-10 |
Marengo Therapeutics Inc |
Multifunctional molecules binding to TCR and uses thereof
|
WO2022214652A1
(en)
|
2021-04-09 |
2022-10-13 |
Ose Immunotherapeutics |
Scaffold for bifunctioanl molecules comprising pd-1 or cd28 and sirp binding domains
|
IL307419A
(en)
|
2021-04-09 |
2023-12-01 |
Ose Immunotherapeutics |
A new scaffold for bifunctional molecules with improved properties
|
IL307821A
(en)
|
2021-04-30 |
2023-12-01 |
Hoffmann La Roche |
Dosage for treatment with BISPIFIC ANTI-CD20/ANTI-CD3 antibody
|
WO2022228705A1
(en)
|
2021-04-30 |
2022-11-03 |
F. Hoffmann-La Roche Ag |
Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate
|
CN117642428A
(zh)
|
2021-05-03 |
2024-03-01 |
Ucb生物制药有限责任公司 |
抗体
|
CA3214582A1
(en)
|
2021-05-07 |
2022-11-10 |
Martin SAHLIN |
Pharmaceutical compositions comprising bispecific antibodies binding to b7h4 and cd3
|
EP4337255A1
(en)
*
|
2021-05-10 |
2024-03-20 |
MedImmune, LLC |
Modified fcrn binding fragments with improved half-life
|
WO2022237856A1
(zh)
|
2021-05-12 |
2022-11-17 |
江苏恒瑞医药股份有限公司 |
特异性结合rankl和ngf的抗原结合分子及其医药用途
|
WO2022237882A1
(zh)
|
2021-05-14 |
2022-11-17 |
江苏恒瑞医药股份有限公司 |
一种抗原结合分子
|
TW202309094A
(zh)
|
2021-05-18 |
2023-03-01 |
美商健生生物科技公司 |
用於識別癌症患者以進行組合治療之方法
|
WO2022261510A1
(en)
|
2021-06-11 |
2022-12-15 |
Sage Therapeutics, Inc. |
Neuroactive steroid for the treatment of alzheimer's disease
|
EP4355784A1
(en)
|
2021-06-15 |
2024-04-24 |
Xencor, Inc. |
Heterodimeric antibodies that bind claudin18.2 and cd3
|
WO2022266223A1
(en)
|
2021-06-16 |
2022-12-22 |
Alector Llc |
Bispecific anti-mertk and anti-pdl1 antibodies and methods of use thereof
|
EP4355783A1
(en)
|
2021-06-16 |
2024-04-24 |
Alector LLC |
Monovalent anti-mertk antibodies and methods of use thereof
|
KR20240021859A
(ko)
|
2021-06-18 |
2024-02-19 |
에프. 호프만-라 로슈 아게 |
이중특이적 항-ccl2 항체
|
EP4359435A1
(en)
|
2021-06-21 |
2024-05-01 |
Genmab A/S |
Combination dosage regime of cd137 and pd-l1 binding agents
|
TW202317627A
(zh)
|
2021-06-25 |
2023-05-01 |
日商中外製藥股份有限公司 |
抗ctla-4抗體
|
AR126236A1
(es)
|
2021-06-25 |
2023-10-04 |
Chugai Pharmaceutical Co Ltd |
Uso del anticuerpo anti-ctla-4
|
EP4363449A2
(en)
|
2021-07-02 |
2024-05-08 |
Genentech, Inc. |
Methods and compositions for treating cancer
|
KR20240032991A
(ko)
|
2021-07-09 |
2024-03-12 |
얀센 바이오테크 인코포레이티드 |
항-tnf 항체 조성물의 생성을 위한 제조 방법
|
CN117916260A
(zh)
|
2021-07-09 |
2024-04-19 |
詹森生物科技公司 |
用于制备抗il12/il23抗体组合物的制造方法
|
KR20240034218A
(ko)
|
2021-07-09 |
2024-03-13 |
얀센 바이오테크 인코포레이티드 |
항-tnf 항체 조성물을 생산하기 위한 제조 방법
|
TW202317635A
(zh)
|
2021-07-14 |
2023-05-01 |
大陸商江蘇恆瑞醫藥股份有限公司 |
特異性結合hgfr和egfr的抗原結合分子及其醫藥用途
|
KR20240036570A
(ko)
|
2021-07-22 |
2024-03-20 |
에프. 호프만-라 로슈 아게 |
이종이량체 Fc 도메인 항체
|
US20230146665A1
(en)
|
2021-07-27 |
2023-05-11 |
Xencor, Inc. |
Il-18-fc fusion proteins
|
CA3227537A1
(en)
|
2021-07-27 |
2023-02-02 |
Morphosys Ag |
Combinations of antigen binding molecules
|
CA3224180A1
(en)
|
2021-07-28 |
2023-02-02 |
F. Hoffmann-La Roche Ag |
Methods and compositions for treating cancer
|
GB202111905D0
(en)
|
2021-08-19 |
2021-10-06 |
UCB Biopharma SRL |
Antibodies
|
WO2023028612A2
(en)
|
2021-08-27 |
2023-03-02 |
Board Of Regents, The University Of Texas System |
Anti-tslpr (crlf2) antibodies
|
WO2023031473A1
(en)
|
2021-09-06 |
2023-03-09 |
Genmab B.V. |
Antibodies capable of binding to cd27, variants thereof and uses thereof
|
KR20240055002A
(ko)
|
2021-09-13 |
2024-04-26 |
얀센 바이오테크 인코포레이티드 |
암 치료를 위한 CD33 x Vδ2 다중특이성 항체
|
KR20230041210A
(ko)
*
|
2021-09-17 |
2023-03-24 |
고려대학교 산학협력단 |
Fc 감마 수용체와의 결합력이 증대된 Fc 변이체
|
WO2023046071A1
(zh)
|
2021-09-23 |
2023-03-30 |
江苏恒瑞医药股份有限公司 |
抗klb抗体及用途
|
WO2023046322A1
(en)
|
2021-09-24 |
2023-03-30 |
Janssen Pharmaceutica Nv |
Proteins comprising cd20 binding domains, and uses thereof
|
WO2023049922A1
(en)
|
2021-09-27 |
2023-03-30 |
Xencor, Inc. |
B-cell maturation antigen (bcma) binding domain compositions
|
JPWO2023053282A1
(pt)
|
2021-09-29 |
2023-04-06 |
|
|
TW202323304A
(zh)
|
2021-09-30 |
2023-06-16 |
大陸商江蘇恆瑞醫藥股份有限公司 |
抗il23抗體融合蛋白及用途
|
TW202333781A
(zh)
|
2021-10-08 |
2023-09-01 |
日商中外製藥股份有限公司 |
抗hla-dq2﹒5抗體製劑
|
WO2023057571A1
(en)
|
2021-10-08 |
2023-04-13 |
Genmab A/S |
Antibodies binding to cd30 and cd3
|
CA3234731A1
(en)
|
2021-10-14 |
2023-04-20 |
F. Hoffmann-La Roche Ag |
New interleukin-7 immunoconjugates
|
WO2023062048A1
(en)
|
2021-10-14 |
2023-04-20 |
F. Hoffmann-La Roche Ag |
Alternative pd1-il7v immunoconjugates for the treatment of cancer
|
CA3237038A1
(en)
|
2021-11-01 |
2023-05-04 |
Janssen Biotech, Inc. |
Compositions and methods for the modulation of beta chain-mediated immunity
|
US20230151095A1
(en)
|
2021-11-12 |
2023-05-18 |
Xencor, Inc. |
Bispecific antibodies that bind to b7h3 and nkg2d
|
WO2023089587A1
(en)
|
2021-11-22 |
2023-05-25 |
Janssen Biotech, Inc. |
Compositions comprising enhanced multispecific binding agents for an immune response
|
WO2023094282A1
(en)
|
2021-11-25 |
2023-06-01 |
F. Hoffmann-La Roche Ag |
Quantification of low amounts of antibody sideproducts
|
US20230183360A1
(en)
|
2021-12-09 |
2023-06-15 |
Janssen Biotech, Inc. |
Use of Amivantamab to Treat Colorectal Cancer
|
AR127887A1
(es)
|
2021-12-10 |
2024-03-06 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y plap
|
WO2023111112A1
(en)
*
|
2021-12-15 |
2023-06-22 |
Medimmune Limited |
Treatment using heterodimeric relaxin fusions
|
US20230295348A1
(en)
|
2022-01-24 |
2023-09-21 |
Novimmune Sa |
Composition and methods for the selective activation of cytokine signaling pathways
|
TW202342057A
(zh)
|
2022-02-07 |
2023-11-01 |
美商健生生物科技公司 |
用於減少用egfr/met雙特異性抗體治療之患者的輸注相關反應之方法
|
WO2023164510A1
(en)
|
2022-02-23 |
2023-08-31 |
Xencor, Inc. |
Anti-cd28 x anti-psma antibodies
|
US20240059786A1
(en)
|
2022-02-24 |
2024-02-22 |
Xencor, Inc. |
Anti-cd28 x anti-trop2 antibodies
|
US20230340128A1
(en)
|
2022-02-24 |
2023-10-26 |
Xencor, Inc. |
Anti-cd28 x anti-msln antibodies
|
US20240002544A1
(en)
|
2022-03-07 |
2024-01-04 |
Novimmune Sa |
Cd28 bispecific antibodies for targeted t cell activation
|
WO2023174925A1
(en)
|
2022-03-14 |
2023-09-21 |
Novimmune Sa |
Bispecific gpc3xcd28 and gpc3xcd3 antibodies and their combination for targeted killing of gpc3 positive malignant cells
|
WO2023174521A1
(en)
|
2022-03-15 |
2023-09-21 |
Genmab A/S |
Binding agents binding to epcam and cd137
|
WO2023180353A1
(en)
|
2022-03-23 |
2023-09-28 |
F. Hoffmann-La Roche Ag |
Combination treatment of an anti-cd20/anti-cd3 bispecific antibody and chemotherapy
|
TW202346337A
(zh)
|
2022-03-29 |
2023-12-01 |
美商恩格姆生物製藥公司 |
Ilt3及cd3結合劑以及其使用方法
|
US20240025968A1
(en)
|
2022-04-07 |
2024-01-25 |
Xencor, Inc. |
LAG-3 TARGETED HETERODIMERIC FUSION PROTEINS CONTAINING IL-15/IL-15RA Fc-FUSION PROTEINS AND LAG-3 ANTIGEN BINDING DOMAINS
|
TW202404637A
(zh)
|
2022-04-13 |
2024-02-01 |
瑞士商赫孚孟拉羅股份公司 |
抗cd20/抗cd3雙特異性抗體之醫藥組成物及使用方法
|
US20230383012A1
(en)
|
2022-04-13 |
2023-11-30 |
Xencor, Inc. |
Antibodies that bind pd-l1, pd-l2, and/or cd28
|
WO2023202967A1
(en)
|
2022-04-19 |
2023-10-26 |
F. Hoffmann-La Roche Ag |
Improved production cells
|
WO2023218046A1
(en)
|
2022-05-12 |
2023-11-16 |
Genmab A/S |
Binding agents capable of binding to cd27 in combination therapy
|
WO2023218051A1
(en)
|
2022-05-12 |
2023-11-16 |
Genmab A/S |
Binding agents capable of binding to cd27 in combination therapy
|
WO2023227641A1
(en)
|
2022-05-27 |
2023-11-30 |
Glaxosmithkline Intellectual Property Development Limited |
Use of tnf-alpha binding proteins and il-7 binding proteins in medical treatment
|
WO2023232961A1
(en)
|
2022-06-03 |
2023-12-07 |
F. Hoffmann-La Roche Ag |
Improved production cells
|
WO2024003837A1
(en)
|
2022-06-30 |
2024-01-04 |
Janssen Biotech, Inc. |
Use of anti-egfr/anti-met antibody to treat gastric or esophageal cancer
|
WO2024003376A1
(en)
|
2022-07-01 |
2024-01-04 |
Alk-Abelló A/S |
Displacers of ige-fceri
|
WO2024026471A1
(en)
|
2022-07-29 |
2024-02-01 |
Alector Llc |
Cd98hc antigen-binding domains and uses therefor
|
WO2024026472A2
(en)
|
2022-07-29 |
2024-02-01 |
Alector Llc |
Transferrin receptor antigen-binding domains and uses therefor
|
WO2024028386A1
(en)
|
2022-08-02 |
2024-02-08 |
Ose Immunotherapeutics |
Multifunctional molecule directed against cd28
|
CN115353552B
(zh)
*
|
2022-08-19 |
2023-07-18 |
山东大学 |
一种降低蛋白质变性温度的方法及其突变体与应用
|
WO2024079015A1
(en)
|
2022-10-10 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Combination therapy of a gprc5d tcb and imids
|
WO2024079010A1
(en)
|
2022-10-10 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Combination therapy of a gprc5d tcb and cd38 antibodies
|
WO2024079009A1
(en)
|
2022-10-10 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Combination therapy of a gprc5d tcb and proteasome inhibitors
|
WO2024079069A1
(en)
|
2022-10-12 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Method for classifying cells
|
WO2024084052A1
(en)
|
2022-10-21 |
2024-04-25 |
Novimmune Sa |
Pd-l1xcd28 bispecific antibodies for immune checkpoint-dependent t cell activation
|
WO2024089551A1
(en)
|
2022-10-25 |
2024-05-02 |
Janssen Biotech, Inc. |
Msln and cd3 binding agents and methods of use thereof
|
WO2024092038A2
(en)
|
2022-10-25 |
2024-05-02 |
Ablexis, Llc |
Anti-cd3 antibodies
|
WO2024094660A1
(en)
|
2022-10-31 |
2024-05-10 |
Genmab A/S |
Cd38 antibodies and uses thereof
|
WO2024095173A1
(en)
|
2022-11-02 |
2024-05-10 |
Janssen Biotech, Inc. |
Methods of treating cancers
|
WO2024102636A1
(en)
|
2022-11-07 |
2024-05-16 |
Xencor, Inc. |
Bispecific antibodies that bind to b7h3 and mica/b
|
WO2024102693A2
(en)
|
2022-11-07 |
2024-05-16 |
Xencor, Inc. |
Il-18-fc fusion proteins
|
WO2024102948A1
(en)
|
2022-11-11 |
2024-05-16 |
Celgene Corporation |
Fc receptor-homolog 5 (fcrh5) specific binding molecules and bispecific t-cell engaging antibodies including same and related methods
|
WO2024100170A1
(en)
|
2022-11-11 |
2024-05-16 |
F. Hoffmann-La Roche Ag |
Antibodies binding to hla-a*02/foxp3
|