MX9700764A - Compuestos novedosos. - Google Patents

Compuestos novedosos.

Info

Publication number
MX9700764A
MX9700764A MX9700764A MX9700764A MX9700764A MX 9700764 A MX9700764 A MX 9700764A MX 9700764 A MX9700764 A MX 9700764A MX 9700764 A MX9700764 A MX 9700764A MX 9700764 A MX9700764 A MX 9700764A
Authority
MX
Mexico
Prior art keywords
novel compounds
antagonist
mutant
fragment
human immunoglobulin
Prior art date
Application number
MX9700764A
Other languages
English (en)
Inventor
Michael Joseph Browne
Kay Elizabeth Murphy
Conrad Gerald Chapman
Helen Elizabeth Clinkenbeard
Peter Ronald Young
Allan Richard Shatzman
Original Assignee
Smithkline Beecham Plc
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9415379A external-priority patent/GB9415379D0/en
Application filed by Smithkline Beecham Plc, Smithkline Beecham Corp filed Critical Smithkline Beecham Plc
Publication of MX9700764A publication Critical patent/MX9700764A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5406IL-4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Una proteína que tiene actividad antagonista de IL4 y/o IL13 o actividad antagonista parcial comprende un mutante o variante de IL4 fusionado a por lo menos un dominio constante de inmunoglobulina humana o fragmento de la misma.
MX9700764A 1994-07-29 1995-07-28 Compuestos novedosos. MX9700764A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9415379A GB9415379D0 (en) 1994-07-29 1994-07-29 Novel compounds
US46829795A 1995-06-06 1995-06-06
PCT/EP1995/003036 WO1996004388A1 (en) 1994-07-29 1995-07-28 Novel compounds

Publications (1)

Publication Number Publication Date
MX9700764A true MX9700764A (es) 1997-05-31

Family

ID=26305369

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9700764A MX9700764A (es) 1994-07-29 1995-07-28 Compuestos novedosos.

Country Status (13)

Country Link
EP (1) EP0770135A1 (es)
JP (1) JPH10503371A (es)
CN (1) CN1117155C (es)
AU (1) AU3382595A (es)
BR (1) BR9508469A (es)
CA (1) CA2196200A1 (es)
CZ (1) CZ25697A3 (es)
HU (1) HUT76369A (es)
MX (1) MX9700764A (es)
NO (1) NO970374L (es)
NZ (1) NZ292124A (es)
PL (1) PL182665B1 (es)
WO (1) WO1996004388A1 (es)

Families Citing this family (203)

* Cited by examiner, † Cited by third party
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