DK0663916T3 - O-alkyleret rapamycinderivat og dets anvendelse, især som immunosuppressivt middel - Google Patents

O-alkyleret rapamycinderivat og dets anvendelse, især som immunosuppressivt middel

Info

Publication number
DK0663916T3
DK0663916T3 DK93920822T DK93920822T DK0663916T3 DK 0663916 T3 DK0663916 T3 DK 0663916T3 DK 93920822 T DK93920822 T DK 93920822T DK 93920822 T DK93920822 T DK 93920822T DK 0663916 T3 DK0663916 T3 DK 0663916T3
Authority
DK
Denmark
Prior art keywords
alkyl
immunosuppressant
allyl
rapamycin derivative
alkylated rapamycin
Prior art date
Application number
DK93920822T
Other languages
Danish (da)
English (en)
Inventor
Sylvain Cottens
Richard Sedrani
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10723188&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0663916(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK0663916T3 publication Critical patent/DK0663916T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Dental Preparations (AREA)
DK93920822T 1992-10-09 1993-09-24 O-alkyleret rapamycinderivat og dets anvendelse, især som immunosuppressivt middel DK0663916T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929221220A GB9221220D0 (en) 1992-10-09 1992-10-09 Organic componds
PCT/EP1993/002604 WO1994009010A1 (fr) 1992-10-09 1993-09-24 Derives o-alkyles de la rapamycine et leur utilisation, en particulier comme immunosuppresseurs

Publications (1)

Publication Number Publication Date
DK0663916T3 true DK0663916T3 (da) 1999-08-09

Family

ID=10723188

Family Applications (2)

Application Number Title Priority Date Filing Date
DK97114343T DK0867438T3 (da) 1992-10-09 1993-09-24 Rapamycin-derivater og deres anvendelse, især som immunosuppressive midler
DK93920822T DK0663916T3 (da) 1992-10-09 1993-09-24 O-alkyleret rapamycinderivat og dets anvendelse, især som immunosuppressivt middel

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK97114343T DK0867438T3 (da) 1992-10-09 1993-09-24 Rapamycin-derivater og deres anvendelse, især som immunosuppressive midler

Country Status (28)

Country Link
US (2) US5665772A (fr)
EP (3) EP0663916B1 (fr)
JP (2) JP3117462B2 (fr)
KR (2) KR100308598B1 (fr)
AT (2) ATE272063T1 (fr)
AU (1) AU676198B2 (fr)
BR (1) BR1100353A (fr)
CA (2) CA2145383C (fr)
CY (2) CY2125B1 (fr)
CZ (1) CZ283333B6 (fr)
DE (3) DE69333577T2 (fr)
DK (2) DK0867438T3 (fr)
ES (2) ES2124793T3 (fr)
FI (2) FI109540B (fr)
FR (1) FR04C0012I2 (fr)
GB (1) GB9221220D0 (fr)
GE (1) GEP20002331B (fr)
HU (1) HU224074B1 (fr)
LU (1) LU91104I2 (fr)
NL (1) NL300154I2 (fr)
NO (3) NO307053B1 (fr)
NZ (1) NZ256026A (fr)
PL (1) PL176174B1 (fr)
PT (1) PT867438E (fr)
RO (1) RO114451B1 (fr)
RU (1) RU2143434C1 (fr)
SK (2) SK286054B6 (fr)
WO (1) WO1994009010A1 (fr)

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* Cited by examiner, † Cited by third party
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NL300154I2 (nl) 2004-10-01
DE122004000033I1 (de) 2006-11-16
US5665772A (en) 1997-09-09
CY2125B1 (en) 2002-06-21
FI20001943A (fi) 2000-09-04
LU91104I2 (fr) 2004-11-29
NO2017067I2 (no) 2017-12-07
WO1994009010A1 (fr) 1994-04-28
SK285256B6 (sk) 2006-10-05
DE69333577T2 (de) 2005-07-21
BR1100353A (pt) 2000-06-06
ES2124793T3 (es) 1999-02-16
EP0663916B1 (fr) 1998-11-25
FR04C0012I1 (fr) 2004-09-17
NO951312L (no) 1995-06-08
SK46595A3 (en) 1995-08-09
AU676198B2 (en) 1997-03-06
DK0867438T3 (da) 2004-12-06
CA2476257C (fr) 2009-11-10
CA2476257A1 (fr) 1994-04-28
FR04C0012I2 (fr) 2005-02-11
GB9221220D0 (en) 1992-11-25
NO307053B1 (no) 2000-01-31
HU224074B1 (hu) 2005-05-30
PL176174B1 (pl) 1999-04-30
EP0867438A1 (fr) 1998-09-30
SK286054B6 (sk) 2008-02-05
NL300154I1 (nl) 2004-09-01
ATE173736T1 (de) 1998-12-15

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