CA1252789A - Mitomycin analogs - Google Patents

Mitomycin analogs

Info

Publication number: CA1252789A
Authority: CA; Canada
Prior art keywords: lower alkyl; methoxy; methyl; indole; hydroxymethyl
Prior art date: 1983-02-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA000446811A

Other languages

English (en)

French (fr)

Inventor

William A. Remers

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

University Patents Inc

Original Assignee

University Patents Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-02-07

Filing date

1984-02-06

Publication date

1989-04-18

1984-02-06 Application filed by University Patents Inc filed Critical University Patents Inc

1989-04-18 Application granted granted Critical

1989-04-18 Publication of CA1252789A publication Critical patent/CA1252789A/en

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CA000446811A 1983-02-07 1984-02-06 Mitomycin analogs Expired CA1252789A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US46461283A	1983-02-07	1983-02-07
US464,612		1983-02-07

Publications (1)

Publication Number	Publication Date
CA1252789A true CA1252789A (en)	1989-04-18

Family

ID=23844605

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000446811A Expired CA1252789A (en)	1983-02-07	1984-02-06	Mitomycin analogs

Country Status (29)

Country	Link
JP (1)	JPS59152384A (de)
KR (1)	KR900006854B1 (de)
AT (1)	AT385509B (de)
AU (1)	AU571193B2 (de)
BE (1)	BE898856A (de)
CA (1)	CA1252789A (de)
CH (1)	CH658658A5 (de)
DD (1)	DD233844A5 (de)
DE (1)	DE3403922A1 (de)
DK (1)	DK161890C (de)
ES (1)	ES8607305A1 (de)
FI (1)	FI80698C (de)
FR (1)	FR2540500B1 (de)
GB (1)	GB2134514B (de)
GR (1)	GR81455B (de)
HU (1)	HU190236B (de)
IE (1)	IE56814B1 (de)
IL (1)	IL70897A (de)
IT (1)	IT1178855B (de)
LU (1)	LU85199A1 (de)
NL (1)	NL8400338A (de)
NO (1)	NO161374C (de)
NZ (1)	NZ206932A (de)
OA (1)	OA07654A (de)
PH (1)	PH20249A (de)
PT (1)	PT78067B (de)
SE (1)	SE461982B (de)
YU (1)	YU44984B (de)
ZA (1)	ZA84788B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4487769A (en) *	1982-06-04	1984-12-11	Bristol-Myers Company	Amidines
CA1282069C (en) *	1985-09-12	1991-03-26	Damon L. Meyer	Antibody complexes of hapten-modified diagnostic or therapeutic agents
JPS63150282A (ja) *	1986-12-13	1988-06-22	Kyowa Hakko Kogyo Co Ltd	マイトマイシン誘導体
JPS63246379A (ja) *	1987-03-31	1988-10-13	Kyowa Hakko Kogyo Co Ltd	７−ｎ，８−ｎ−エチレンマイトマイシン８−イミン類
EP0485904B1 (de) *	1990-11-13	1997-08-20	Kyowa Hakko Kogyo Co., Ltd.	Mitomycinderivate

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3332944A (en) *	1964-11-02	1967-07-25	American Cyanamid Co	Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) *	1977-08-31	1979-03-24	Kyowa Hakko Kogyo Co Ltd	Mitomycin c derivatives
US4268676A (en) *	1979-12-05	1981-05-19	University Patents, Inc.	Mitomycin analogs
JPS5686184A (en) *	1979-12-17	1981-07-13	Kyowa Hakko Kogyo Co Ltd	Novel mitomycin c derivative
NZ199617A (en) *	1981-05-15	1985-08-30	University Patents Inc	Azirino(2',3',:3,4)pyrrolo(1,2-a)indole-4,7-dione derivatives and pharmaceutical compositions
US4487769A (en) *	1982-06-04	1984-12-11	Bristol-Myers Company	Amidines
US4642352A (en) *	1983-12-23	1987-02-10	Bristol-Myers Company	Acylamino mitosanes

1984
- 1984-01-25 NZ NZ206932A patent/NZ206932A/en unknown
- 1984-01-27 GB GB08402233A patent/GB2134514B/en not_active Expired
- 1984-02-02 ZA ZA84788A patent/ZA84788B/xx unknown
- 1984-02-03 NL NL8400338A patent/NL8400338A/nl not_active Application Discontinuation
- 1984-02-03 AU AU24073/84A patent/AU571193B2/en not_active Ceased
- 1984-02-04 DE DE19843403922 patent/DE3403922A1/de not_active Withdrawn
- 1984-02-06 PT PT78067A patent/PT78067B/pt not_active IP Right Cessation
- 1984-02-06 NO NO840433A patent/NO161374C/no unknown
- 1984-02-06 ES ES529478A patent/ES8607305A1/es not_active Expired
- 1984-02-06 AT AT0037684A patent/AT385509B/de not_active IP Right Cessation
- 1984-02-06 IE IE272/84A patent/IE56814B1/en not_active IP Right Cessation
- 1984-02-06 DD DD84259885A patent/DD233844A5/de not_active IP Right Cessation
- 1984-02-06 PH PH30204A patent/PH20249A/en unknown
- 1984-02-06 HU HU84483A patent/HU190236B/hu not_active IP Right Cessation
- 1984-02-06 DK DK052484A patent/DK161890C/da active
- 1984-02-06 CH CH550/84A patent/CH658658A5/de not_active IP Right Cessation
- 1984-02-06 CA CA000446811A patent/CA1252789A/en not_active Expired
- 1984-02-06 GR GR73720A patent/GR81455B/el unknown
- 1984-02-07 FR FR8401845A patent/FR2540500B1/fr not_active Expired
- 1984-02-07 YU YU217/84A patent/YU44984B/xx unknown
- 1984-02-07 FI FI840502A patent/FI80698C/fi not_active IP Right Cessation
- 1984-02-07 OA OA58227A patent/OA07654A/xx unknown
- 1984-02-07 IL IL70897A patent/IL70897A/xx unknown
- 1984-02-07 IT IT67113/84A patent/IT1178855B/it active
- 1984-02-07 LU LU85199A patent/LU85199A1/fr unknown
- 1984-02-07 SE SE8400628A patent/SE461982B/sv not_active IP Right Cessation
- 1984-02-07 BE BE0/212351A patent/BE898856A/fr not_active IP Right Cessation
- 1984-02-07 KR KR1019840000574A patent/KR900006854B1/ko not_active IP Right Cessation
- 1984-02-07 JP JP59021505A patent/JPS59152384A/ja active Pending

Also Published As

Publication number	Publication date
FI80698C (fi)	1990-07-10
ATA37684A (de)	1987-09-15
ES529478A0 (es)	1986-05-16
ZA84788B (en)	1984-09-26
IE840272L (en)	1984-08-07
ES8607305A1 (es)	1986-05-16
GB8402233D0 (en)	1984-02-29
PT78067A (en)	1984-03-01
JPS59152384A (ja)	1984-08-31
OA07654A (fr)	1985-05-23
NZ206932A (en)	1987-08-31
GB2134514B (en)	1987-04-01
AU2407384A (en)	1984-08-16
HU190236B (en)	1986-08-28
IL70897A0 (en)	1984-05-31
NO161374C (no)	1989-08-09
FI840502A0 (fi)	1984-02-07
IL70897A (en)	1989-01-31
FI80698B (fi)	1990-03-30
IT1178855B (it)	1987-09-16
IE56814B1 (en)	1991-12-18
KR840007726A (ko)	1984-12-10
AU571193B2 (en)	1988-04-14
GR81455B (de)	1984-12-11
GB2134514A (en)	1984-08-15
PT78067B (en)	1986-03-20
FI840502A (fi)	1984-08-08
DK161890B (da)	1991-08-26
FR2540500B1 (fr)	1987-07-17
DD233844A5 (de)	1986-03-12
YU21784A (en)	1986-10-31
SE8400628D0 (sv)	1984-02-07
NL8400338A (nl)	1984-09-03
SE8400628L (sv)	1984-08-08
AT385509B (de)	1988-04-11
DK52484A (da)	1984-08-08
DE3403922A1 (de)	1984-08-09
BE898856A (fr)	1984-05-30
FR2540500A1 (fr)	1984-08-10
KR900006854B1 (ko)	1990-09-22
LU85199A1 (fr)	1984-05-30
SE461982B (sv)	1990-04-23
DK161890C (da)	1992-02-03
CH658658A5 (de)	1986-11-28
YU44984B (en)	1991-06-30
IT8467113A0 (it)	1984-02-07
NO840433L (no)	1984-08-08
PH20249A (en)	1986-11-10
NO161374B (no)	1989-05-02
DK52484D0 (da)	1984-02-06

Legal Events

Date	Code	Title	Description
2006-04-18	MKEX	Expiry

Publication	Publication Date	Title
EP0800390B1 (de)	2002-12-04	Krebsmittel auf basis von cyclopropylpyrroloindol-oligopeptiden
US4268676A (en)	1981-05-19	Mitomycin analogs
KR870000932B1 (ko)	1987-05-11	아미딘류의 제조 방법
CA1252789A (en)	1989-04-18	Mitomycin analogs
US4746746A (en)	1988-05-24	Mitomycin analogs
CA1244412A (en)	1988-11-08	Mitomycin analogs
US5023253A (en)	1991-06-11	6-substituted mitomycin analogs
US4617389A (en)	1986-10-14	Mitomycin analogs
US4460599A (en)	1984-07-17	Mitomycin analogs
Kundu et al.	1982	N-Alkylated derivatives of 5-fluorouracil
GB2223753A (en)	1990-04-18	Piperazine derivatives
US4590074A (en)	1986-05-20	Bis-amidines
US4579737A (en)	1986-04-01	Bis-amidines
US4885304A (en)	1989-12-05	Mitomycin analogs
AU2003204339B2 (en)	2006-03-30	Cytotoxic Alkaloid Derivatives Including Asmarine A and B Isolated from a Sponge
AU1774099A (en)	1999-07-19	Cytotoxic alkaloid derivatives including asmarine a and b isolated from a sponge
MXPA00006322A (en)	2001-07-03	Cytotoxic alkaloid derivatives including asmarine a and b isolated from a sponge