BG105860A - Heteroaryl-substituted quinolin-2-one derivatives useful as anticancer agents - Google Patents
Heteroaryl-substituted quinolin-2-one derivatives useful as anticancer agentsInfo
- Publication number
- BG105860A BG105860A BG105860A BG10586001A BG105860A BG 105860 A BG105860 A BG 105860A BG 105860 A BG105860 A BG 105860A BG 10586001 A BG10586001 A BG 10586001A BG 105860 A BG105860 A BG 105860A
- Authority
- BG
- Bulgaria
- Prior art keywords
- heteroaryl
- anticancer agents
- derivatives useful
- substituted quinolin
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11970299P | 1999-02-11 | 1999-02-11 | |
PCT/IB2000/000121 WO2000047574A1 (fr) | 1999-02-11 | 2000-02-04 | Derives de quinolin-2-one a substitution heteroaryle convenant comme anti-cancereux |
Publications (1)
Publication Number | Publication Date |
---|---|
BG105860A true BG105860A (en) | 2002-03-29 |
Family
ID=22385869
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG105860A BG105860A (en) | 1999-02-11 | 2001-08-30 | Heteroaryl-substituted quinolin-2-one derivatives useful as anticancer agents |
Country Status (39)
Country | Link |
---|---|
US (3) | US6258824B1 (fr) |
EP (1) | EP1150973B1 (fr) |
JP (3) | JP4090200B2 (fr) |
KR (1) | KR20010102073A (fr) |
CN (1) | CN1340051A (fr) |
AP (1) | AP2001002241A0 (fr) |
AR (1) | AR028985A1 (fr) |
AT (1) | ATE297916T1 (fr) |
AU (1) | AU2124800A (fr) |
BG (1) | BG105860A (fr) |
BR (1) | BR0008202A (fr) |
CA (1) | CA2362394C (fr) |
CO (1) | CO5140097A1 (fr) |
CZ (1) | CZ20012910A3 (fr) |
DE (1) | DE60020812T2 (fr) |
DZ (1) | DZ3009A1 (fr) |
EA (1) | EA200100766A1 (fr) |
EE (1) | EE200100425A (fr) |
ES (1) | ES2243228T3 (fr) |
GT (1) | GT200000014A (fr) |
HK (1) | HK1042096A1 (fr) |
HN (1) | HN2000000019A (fr) |
HR (1) | HRP20010574A2 (fr) |
HU (1) | HUP0105231A3 (fr) |
ID (1) | ID29584A (fr) |
IL (1) | IL144307A0 (fr) |
IS (1) | IS5997A (fr) |
MA (1) | MA26718A1 (fr) |
NO (1) | NO20013909L (fr) |
OA (1) | OA11833A (fr) |
PA (1) | PA8490601A1 (fr) |
PE (1) | PE20001464A1 (fr) |
PL (1) | PL349839A1 (fr) |
SK (1) | SK11002001A3 (fr) |
SV (1) | SV2001000020A (fr) |
TN (1) | TNSN00028A1 (fr) |
TR (2) | TR200201296T2 (fr) |
WO (1) | WO2000047574A1 (fr) |
ZA (1) | ZA200106520B (fr) |
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EP1253921A4 (fr) * | 2000-01-28 | 2004-10-13 | Merck & Co Inc | Traitement ou prevention du cancer de la prostate avec un medicament inhibiteur selectif de cox-2 |
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EP1170011A1 (fr) * | 2000-07-06 | 2002-01-09 | Boehringer Ingelheim International GmbH | Nouvelle utilisation des inhibiteurs de facteur de croissance épidermique |
US7173040B2 (en) | 2000-09-25 | 2007-02-06 | Janssen Pharmaceutica N.V. | Farnesyl transferase inhibiting 6-[(substituted phenyl)methyl]-quinoline and quinazoline derinazoline derivatives |
EP1322644A1 (fr) * | 2000-09-25 | 2003-07-02 | Janssen Pharmaceutica N.V. | Derives de 6-heterocyclylmethyl quinolinone inhibant la farnesyl transferase |
US7053105B2 (en) | 2000-09-25 | 2006-05-30 | Janssen Pharmaceutica, N.V. | Farnesyl transferase inhibiting quinoline and quinazoline derivatives as farnesyl transferase inhibitors |
AU2002220559A1 (en) * | 2000-09-25 | 2002-04-02 | Janssen Pharmaceutica N.V. | Farnesyl transferase inhibiting 6-heterocyclylmethyl quinoline and quinazoline derivatives |
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WO2002042296A1 (fr) | 2000-11-21 | 2002-05-30 | Janssen Pharmaceutica N.V. | Derives benzoheterocycliques inhibant la farnesyl transferase |
ES2260316T3 (es) | 2000-12-27 | 2006-11-01 | Janssen Pharmaceutica N.V. | Derivados de quinazolina y quinolina 4-sustituidos que inhiben la farnesil transferasa. |
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JP2022520361A (ja) | 2019-02-12 | 2022-03-30 | スミトモ ダイニッポン ファーマ オンコロジー, インコーポレイテッド | 複素環式タンパク質キナーゼ阻害剤を含む製剤 |
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EP0988038B1 (fr) * | 1997-06-02 | 2002-08-14 | Janssen Pharmaceutica N.V. | Derives d'(imidazol-5-yl)methyle-2-quinolinone comme inhibiteurs de la proliferation des cellules des muscles lisses |
GEP20033001B (en) | 1998-08-27 | 2003-06-25 | Pfizer Prod Inc | Alkynyl-Substituted Quinolin-2-One Derivatives Useful As Anticancer Agents |
HUP0105231A3 (en) * | 1999-02-11 | 2003-01-28 | Pfizer Prod Inc | Heteroaryl-substituted quinolin-2-one derivatives useful as anticancer agents and medicaments containing the compounds |
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2000
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2001
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2002
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