TW200504057A - Benzothiophene derivative - Google Patents

Benzothiophene derivative

Info

Publication number
TW200504057A
TW200504057A TW093105203A TW93105203A TW200504057A TW 200504057 A TW200504057 A TW 200504057A TW 093105203 A TW093105203 A TW 093105203A TW 93105203 A TW93105203 A TW 93105203A TW 200504057 A TW200504057 A TW 200504057A
Authority
TW
Taiwan
Prior art keywords
benzothiophene derivative
compound
whixh
berepresented
prodrug
Prior art date
Application number
TW093105203A
Other languages
Chinese (zh)
Inventor
Miyuki Asai
Kohsuke Asoh
Ikumi Hyoudoh
Masami Kohchi
Kazunao Masubuchi
Masahiro Sakaitani
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of TW200504057A publication Critical patent/TW200504057A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

This invention relates to a compound useful as an antitumor agent ,a process for producing the same and a medicine containing the compound whixh could berepresented by the formula (I): (wherein R1 represents nitro group, etc.; R2 represents hydrogen atom, etc.; R3 represents C1-4 linear or branched alkyl group), its salt, prodrug or solvate.
TW093105203A 2003-02-27 2004-02-27 Benzothiophene derivative TW200504057A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003050369 2003-02-27

Publications (1)

Publication Number Publication Date
TW200504057A true TW200504057A (en) 2005-02-01

Family

ID=32923343

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093105203A TW200504057A (en) 2003-02-27 2004-02-27 Benzothiophene derivative

Country Status (2)

Country Link
TW (1) TW200504057A (en)
WO (1) WO2004076446A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7524961B2 (en) * 2004-05-03 2009-04-28 Janssen Pharmaceutica, N.V. Diastereoselective addition of lithiated N-methylimidazole on sulfinimines
WO2005105783A1 (en) * 2004-05-03 2005-11-10 Janssen Pharmaceutica N.V. Diastereoselective synthesis process with 6-bromo-4-(3-chlorophenyl)-2-methoxy-quinoline
WO2006101454A1 (en) * 2005-03-21 2006-09-28 S*Bio Pte Ltd Benzothiophene derivatives: preparation and pharmaceutical applications

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000047574A1 (en) * 1999-02-11 2000-08-17 Pfizer Products Inc. Heteroaryl-substituted quinolin-2-one derivatives useful as anticancer agents
ATE409189T1 (en) * 2000-09-25 2008-10-15 Janssen Pharmaceutica Nv FARNESYL TRANSFERASE INHIBITING 6-HETEROCYCLYLMETHYL-QUINOLINE AND QUINAZOLE DERIVATIVES

Also Published As

Publication number Publication date
WO2004076446A1 (en) 2004-09-10

Similar Documents

Publication Publication Date Title
TW200637869A (en) The spiroketal derivatives and the use as therapeutical agent for diabetes of the same
TW200612920A (en) Novel imidazolidine derivatives
WO2008114819A1 (en) Novel adenine compound
DE60301345D1 (en) Stabilized ascorinthic acid derivatives
MY153910A (en) BICYCLIC y-AMINO ACID DERIVATIVE
TW200728307A (en) Novel spirochromanone derivatives
MY149180A (en) Uracil compound having inhibitor activity on human deoxyuridine triphosphatase or salt thereof
GB0100889D0 (en) Compounds
MX2009012885A (en) Novel 1,2,3,4-tetrahydroquinoxaline derivative which has, as substituent, phenyl group having sulfonic acid ester structure or sulfonic acid amide structure introduced therein and has glucocorticoid receptor-binding activity.
TW200604175A (en) Ortho substituted aryl or heteroaryl amide compounds
TNSN07397A1 (en) Acetylene derivatives
MX2007007956A (en) Novel naphthalenic derivatives, method for the preparation thereof, and pharmaceutical compositions containing same á.
DE60214591D1 (en) Pyrazolpyrimidinfungizide
TW200738667A (en) Preparation method for dioxan-2-ylalkylcarbamate derivatives and intermediate thereof
TW200726470A (en) 6,7-unsaturated-7-carbamoylmorphinan derivatives
EA017861B9 (en) Method for producing 4-oxoquinoline compound
PT1753712E (en) Amino-propanol derivatives
TW200714598A (en) Urea derivatives, methods for their manufacture, and uses therefor
TW200716527A (en) Substituted aminoalkyl-and amidoalkyl-benzopyran derivatives
GEP20115166B (en) 2-ARYLINDOLE DERIVATIVES AS mPGES-I INHIBITORS
EP1634874A4 (en) Imidazolidine derivative
MY183326A (en) New dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them
MY138466A (en) Aminoalkoxyndoles as 5-ht6-receptor ligands for the treatment of cns-disorders
GEP20084470B (en) New phenylpyridinylpiperazine compounds, a process for their preparation and pharmaceutical compositions containing them
GEP20074256B (en) Novel benzothiadiazine, process for their preparation and pharmaceutical compositions containing