BR112014006840A2 - derivados de pirrolopirimidina e purina - Google Patents

derivados de pirrolopirimidina e purina

Info

Publication number
BR112014006840A2
BR112014006840A2 BR112014006840A BR112014006840A BR112014006840A2 BR 112014006840 A2 BR112014006840 A2 BR 112014006840A2 BR 112014006840 A BR112014006840 A BR 112014006840A BR 112014006840 A BR112014006840 A BR 112014006840A BR 112014006840 A2 BR112014006840 A2 BR 112014006840A2
Authority
BR
Brazil
Prior art keywords
pyrrolopyrimidine
purine derivatives
compounds
mammals
cell growth
Prior art date
Application number
BR112014006840A
Other languages
English (en)
Inventor
Nagata Asako
Ann Lunney Elizabeth
Cheng Hengmiao
Charles Kath John
Kun-Chin Liu Kevin
Krishnan Nair Sajiv
Channing Sutton Scott
Paul Planken Simon
Otto Johnson Theodore Jr
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47116127&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112014006840(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of BR112014006840A2 publication Critical patent/BR112014006840A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Abstract

resumo patente de invenção: "derivados de pirrolopirimidina e purina". a presente invenção refere-se aos compostos de fórmula (i) ou sais farmaceuticamente aceitáveis dos mesmos, em que q, t, v, w, x, y, z, anel a, r1, r2, r3, r4, r5, r5a, r6, r7, r8, r9, r10, r11, r12, r13, r14, r15, r16, r17 e m são definidos aqui. aqui novos derivados de pirrolopirimidina e purina são úteis no tratamento de crescimento celular anormal, tal como câncer, em mamíferos. modalidades adicionais referem-se a composições farmacêuticas contendo os compostos e a métodos de uso dos compostos e composições no tratamento de crescimento celular anormal em mamíferos.
BR112014006840A 2011-09-22 2012-09-10 derivados de pirrolopirimidina e purina BR112014006840A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161538103P 2011-09-22 2011-09-22
US201261639639P 2012-04-27 2012-04-27
PCT/IB2012/054702 WO2013042006A1 (en) 2011-09-22 2012-09-10 Pyrrolopyrimidine and purine derivatives

Publications (1)

Publication Number Publication Date
BR112014006840A2 true BR112014006840A2 (pt) 2017-04-04

Family

ID=47116127

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014006840A BR112014006840A2 (pt) 2011-09-22 2012-09-10 derivados de pirrolopirimidina e purina

Country Status (28)

Country Link
US (2) US9040547B2 (pt)
EP (1) EP2758402B9 (pt)
JP (1) JP5914667B2 (pt)
KR (1) KR20140059246A (pt)
CN (1) CN103814030A (pt)
AP (1) AP2014007475A0 (pt)
AR (1) AR088760A1 (pt)
AU (1) AU2012311184A1 (pt)
BR (1) BR112014006840A2 (pt)
CA (1) CA2847540C (pt)
CL (2) CL2014002726A1 (pt)
CO (1) CO6910196A2 (pt)
CR (1) CR20140132A (pt)
DO (1) DOP2014000055A (pt)
EA (1) EA201490673A1 (pt)
ES (1) ES2575710T3 (pt)
IL (1) IL231592A0 (pt)
MA (1) MA35451B1 (pt)
MD (1) MD20140023A2 (pt)
MX (1) MX2014003501A (pt)
NI (1) NI201400023A (pt)
PE (1) PE20141228A1 (pt)
SG (1) SG2014014450A (pt)
TN (1) TN2014000115A1 (pt)
TW (1) TWI492946B (pt)
UA (1) UA110259C2 (pt)
UY (1) UY34342A (pt)
WO (1) WO2013042006A1 (pt)

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