SE429966B - Di-0-n-alkylglycerolderivat med immunitetsstimulerande verkan och farmaceutiska beredningar innehallande detta - Google Patents

Di-0-n-alkylglycerolderivat med immunitetsstimulerande verkan och farmaceutiska beredningar innehallande detta

Info

Publication number: SE429966B
Authority: SE; Sweden
Prior art keywords: alkyl; general formula; compounds; carbon atoms; pharmaceutically acceptable
Prior art date: 1978-05-15

Application number

SE7904216A

Other languages

English (en)

Swedish (sv)

Other versions

SE7904216L (sv

Inventor

A R Kraska

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-05-15

Filing date

1979-05-14

Publication date

1983-10-10

1979-05-14 Application filed by Pfizer filed Critical Pfizer

1979-11-16 Publication of SE7904216L publication Critical patent/SE7904216L/xx

1983-10-10 Publication of SE429966B publication Critical patent/SE429966B/sv

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/44—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reduction and hydrolysis of nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Hydrogenated Pyridines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

SE7904216A 1978-05-15 1979-05-14 Di-0-n-alkylglycerolderivat med immunitetsstimulerande verkan och farmaceutiska beredningar innehallande detta SE429966B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/906,260 US4173641A (en)	1978-05-15	1978-05-15	Di-O-n-alkyl glycerol derivatives as immune stimulants

Publications (2)

Publication Number	Publication Date
SE7904216L SE7904216L (sv)	1979-11-16
SE429966B true SE429966B (sv)	1983-10-10

Family

ID=25422164

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7904216A SE429966B (sv)	1978-05-15	1979-05-14	Di-0-n-alkylglycerolderivat med immunitetsstimulerande verkan och farmaceutiska beredningar innehallande detta

Country Status (38)

Country	Link
US (1)	US4173641A (nl)
JP (2)	JPS5924974B2 (nl)
AR (1)	AR221724A1 (nl)
AT (1)	AT372678B (nl)
AU (1)	AU513771B2 (nl)
BE (1)	BE876229A (nl)
CA (1)	CA1105935A (nl)
CH (1)	CH639939A5 (nl)
DD (1)	DD144540A5 (nl)
DE (1)	DE2919514C2 (nl)
DK (1)	DK149946C (nl)
EG (1)	EG15252A (nl)
ES (1)	ES480565A1 (nl)
FI (1)	FI69450C (nl)
FR (1)	FR2426039A1 (nl)
GB (1)	GB2021580B (nl)
GR (1)	GR72419B (nl)
GT (1)	GT197957869A (nl)
HK (1)	HK13584A (nl)
HU (1)	HU180283B (nl)
IE (1)	IE48229B1 (nl)
IL (1)	IL57268A (nl)
IN (1)	IN150574B (nl)
IT (1)	IT1115217B (nl)
KE (1)	KE3354A (nl)
LU (1)	LU81253A1 (nl)
MY (1)	MY8500096A (nl)
NL (1)	NL175524C (nl)
NO (1)	NO151285C (nl)
NZ (1)	NZ190444A (nl)
PH (1)	PH15256A (nl)
PL (1)	PL123910B1 (nl)
PT (1)	PT69607A (nl)
SE (1)	SE429966B (nl)
SG (1)	SG65483G (nl)
SU (1)	SU1122220A3 (nl)
YU (1)	YU41156B (nl)
ZA (1)	ZA792306B (nl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4255426A (en) *	1979-07-09	1981-03-10	Pfizer Inc.	1-(2-Hydroxy-3-n-alkoxypropyl)-4-substituted-piperazines and piperidines
US4312877A (en) *	1979-07-09	1982-01-26	Pfizer Inc.	1-(2-Hydroxy-3-n-alkoxypropyl)-4-substituted piperidines, pharmaceutical compositions, thereof and use thereof
US4310550A (en) *	1979-10-26	1982-01-12	Pfizer Inc.	Lipid amines formulated with fat or lipid emulsions as vaccine adjuvants
US4395394A (en) *	1979-10-26	1983-07-26	Pfizer Inc.	Use of lipid amines formulated with fat or lipid emulsions as vaccine adjuvants
JPS60105650A (ja) *	1983-11-14	1985-06-11	Ono Pharmaceut Co Ltd	グリセリン誘導体、その製造方法及びその誘導体を含有する薬剤
US4880626A (en) *	1985-01-18	1989-11-14	Mcmichael John	Immunotherapeutic methods and compositions for the treatment of diseases of viral origin, including acquired immune deficiency syndrome
JPS62156230A (ja) *	1985-12-27	1987-07-11	Nippon Steel Corp	帯状物の蛇行修正方法
US4842862A (en) *	1986-07-03	1989-06-27	International Minerals & Chemical Corp.	Immunostimulating agents
ZA899436B (en) *	1988-12-12	1990-08-29	Ciba Geigy	Piperidine derivatives
WO2005077963A1 (fr) *	2004-01-16	2005-08-25	Institut Superieur Agricole De Beauvais	DErivEs de saccharides et d'itols possEdant un groupement O-alkyle ou un groupement O-alkyle et un groupement O-n-butanoyle. Applications comme mEdicaments dans les pathologies prolifEratives tumorales ou bEnignes.
WO2011076807A2 (en)	2009-12-23	2011-06-30	Novartis Ag	Lipids, lipid compositions, and methods of using them

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2738351A (en) *	1952-08-02	1956-03-13	Bristol Lab Inc	Substituted glycerol ethers
US3432602A (en) *	1967-12-20	1969-03-11	Astra Ab	Oral alkyl glycerol ether improvement in radiation,radiomimetic,or cytostatic tumor therapies
US3943173A (en) *	1972-11-22	1976-03-09	Smithkline Corporation	3-Alkylamino- alpha-aminomethyl-4-hydroxybenzyl alcohols
US4012528A (en) *	1974-06-03	1977-03-15	Smithkline Corporation	α-AMINOALKYL-3-(1,2-DIHYDROXYETHYL)-4-HYDROXY-BENZYL ALCOHOLS HAVING β-ADRENERGIC STIMULANT ACTIVITY
US4069223A (en) *	1977-05-02	1978-01-17	G. D. Searle & Co.	4-Aminomethyl-1-(3,3,3-triarylpropyl)-4-arylpiperidine and derivatives thereof
US4166132A (en) *	1977-08-18	1979-08-28	Pfizer Inc.	Antiviral amine derivatives of glycerol and propanediols

1978
- 1978-05-15 US US05/906,260 patent/US4173641A/en not_active Expired - Lifetime
1979
- 1979-03-12 DK DK102479A patent/DK149946C/da not_active IP Right Cessation
- 1979-03-13 IN IN173/DEL/79A patent/IN150574B/en unknown
- 1979-04-18 PH PH22379A patent/PH15256A/en unknown
- 1979-04-26 CH CH395479A patent/CH639939A5/fr not_active IP Right Cessation
- 1979-05-10 YU YU1094/79A patent/YU41156B/xx unknown
- 1979-05-11 CA CA327,431A patent/CA1105935A/en not_active Expired
- 1979-05-11 AU AU47016/79A patent/AU513771B2/en not_active Ceased
- 1979-05-14 GT GT197957869A patent/GT197957869A/es unknown
- 1979-05-14 FI FI791531A patent/FI69450C/fi not_active IP Right Cessation
- 1979-05-14 NO NO791604A patent/NO151285C/no unknown
- 1979-05-14 BE BE0/195142A patent/BE876229A/xx not_active IP Right Cessation
- 1979-05-14 ES ES79480565A patent/ES480565A1/es not_active Expired
- 1979-05-14 NL NLAANVRAGE7903769,A patent/NL175524C/nl active Search and Examination
- 1979-05-14 LU LU81253A patent/LU81253A1/xx unknown
- 1979-05-14 NZ NZ190444A patent/NZ190444A/xx unknown
- 1979-05-14 IT IT22664/79A patent/IT1115217B/it active
- 1979-05-14 IL IL57268A patent/IL57268A/xx unknown
- 1979-05-14 SU SU792764751A patent/SU1122220A3/ru active
- 1979-05-14 ZA ZA792306A patent/ZA792306B/xx unknown
- 1979-05-14 FR FR7912175A patent/FR2426039A1/fr active Granted
- 1979-05-14 SE SE7904216A patent/SE429966B/sv not_active IP Right Cessation
- 1979-05-14 GB GB7916722A patent/GB2021580B/en not_active Expired
- 1979-05-14 PT PT69607A patent/PT69607A/pt unknown
- 1979-05-14 PL PL1979215573A patent/PL123910B1/pl unknown
- 1979-05-14 HU HU79PI677A patent/HU180283B/hu not_active IP Right Cessation
- 1979-05-14 AT AT0356179A patent/AT372678B/de not_active IP Right Cessation
- 1979-05-14 GR GR59080A patent/GR72419B/el unknown
- 1979-05-14 JP JP54059019A patent/JPS5924974B2/ja not_active Expired
- 1979-05-15 DD DD79212895A patent/DD144540A5/de unknown
- 1979-05-15 AR AR276517A patent/AR221724A1/es active
- 1979-05-15 EG EG289/79A patent/EG15252A/xx active
- 1979-05-15 DE DE2919514A patent/DE2919514C2/de not_active Expired
- 1979-08-08 IE IE938/79A patent/IE48229B1/en not_active IP Right Cessation
1982
- 1982-12-29 JP JP57235061A patent/JPS58131947A/ja active Granted
1983
- 1983-11-02 SG SG654/83A patent/SG65483G/en unknown
- 1983-11-22 KE KE3354A patent/KE3354A/xx unknown
1984
- 1984-02-16 HK HK135/84A patent/HK13584A/xx unknown
1985
- 1985-12-30 MY MY96/85A patent/MY8500096A/xx unknown

Also Published As

Publication number	Publication date
DD144540A5 (de)	1980-10-22
NO791604L (no)	1979-11-16
PH15256A (en)	1982-11-02
IT1115217B (it)	1986-02-03
AU4701679A (en)	1979-11-22
NL175524C (nl)	1984-11-16
CH639939A5 (fr)	1983-12-15
GT197957869A (es)	1980-11-04
PT69607A (en)	1979-06-01
DE2919514C2 (de)	1982-06-03
SE7904216L (sv)	1979-11-16
AT372678B (de)	1983-11-10
JPS5924974B2 (ja)	1984-06-13
BE876229A (fr)	1979-11-14
US4173641A (en)	1979-11-06
CA1105935A (en)	1981-07-28
MY8500096A (en)	1985-12-31
JPS58131947A (ja)	1983-08-06
FI69450C (fi)	1986-02-10
SG65483G (en)	1984-07-27
YU41156B (en)	1986-12-31
HK13584A (en)	1984-02-24
ATA356179A (de)	1983-03-15
FR2426039B1 (nl)	1983-12-16
IE48229B1 (en)	1984-11-14
HU180283B (en)	1983-02-28
NZ190444A (en)	1981-05-29
DE2919514A1 (de)	1979-11-22
AR221724A1 (es)	1981-03-13
GB2021580B (en)	1982-09-08
LU81253A1 (fr)	1979-12-07
ZA792306B (en)	1980-05-28
GR72419B (nl)	1983-11-03
ES480565A1 (es)	1980-08-16
FR2426039A1 (fr)	1979-12-14
IN150574B (nl)	1982-11-13
GB2021580A (en)	1979-12-05
NO151285B (no)	1984-12-03
NO151285C (no)	1985-03-13
IE790938L (en)	1979-11-15
IL57268A0 (en)	1979-09-30
KE3354A (en)	1983-12-16
IL57268A (en)	1982-05-31
PL123910B1 (en)	1982-12-31
JPS6139301B2 (nl)	1986-09-03
AU513771B2 (en)	1980-12-18
PL215573A1 (nl)	1980-07-01
YU109479A (en)	1983-02-28
DK149946C (da)	1987-06-15
FI69450B (fi)	1985-10-31
NL7903769A (nl)	1979-11-19
JPS55378A (en)	1980-01-05
FI791531A (fi)	1979-11-16
DK149946B (da)	1986-11-03
SU1122220A3 (ru)	1984-10-30
IT7922664A0 (it)	1979-05-14
DK102479A (da)	1979-11-16
EG15252A (en)	1986-09-30

Legal Events

Date

Code

Title

Description

1995-01-31

NUG

Patent has lapsed

Ref document number: 7904216-4

Effective date: 19931210

Format of ref document f/p: F

Publication	Publication Date	Title
CA1102354A (en)	1981-06-02	Antiviral amine derivatives of glycerol
SE429966B (sv)	1983-10-10	Di-0-n-alkylglycerolderivat med immunitetsstimulerande verkan och farmaceutiska beredningar innehallande detta
CA1159827A (en)	1984-01-03	Esters
EP0399504B1 (en)	1995-05-03	Aryloxyphenylpropylamines their preparation and use
JP2687977B2 (ja)	1997-12-08	アリールオキシフエニルプロピルアミンおよびその製造方法および用途
US3205136A (en)	1965-09-07	Antidepressant phenyloxyalkylamines
CA1195328A (en)	1985-10-15	Phenoxypropanolamine derivatives
PT86919B (pt)	1992-05-29	Metodo para a utilizacao de derivados de morfolina em medicina e agricultura e respectivo processo de preparacao
FI75802B (fi)	1988-04-29	Foerfarande foer framstaellning av saosom immunostimulerande aemnen anvaendbara bis- och polydisulfider.
US4318925A (en)	1982-03-09	4-Homoisotwistane derivatives
Curtis	1968	6-Methoxymellein as a phytoalexin
US3929766A (en)	1975-12-30	Novel 2{8 2-(1,3-diazacycloalk-2-enyl){9 benzophenone derivatives and novel 1,3-diazacycloalkenyl{8 2,1-A{9 isoindole derivatives
KR830000771B1 (ko)	1983-04-11	디-0-n-알킬 글리세롤 유도체의 제조방법
JPH0667880B2 (ja)	1994-08-31	ｇｅｍ−ジハロ−１，８−ジアミノ−４−アザ−オクタン類
US4215146A (en)	1980-07-29	Antiviral amine derivatives of glycerol and propanediols
EP0034002A2 (en)	1981-08-19	Carboxamidine derivatives
US3121724A (en)	1964-02-18	Aminoalkyl ethers of 6-halobenzyl-5-indanol and 7-halobenzyl-4-indanol
Fulton et al.	1950	Amoebicidal action and chemical constitution
EP0022371B1 (en)	1983-01-19	Substituted piperazines and piperidines and pharmaceutical compositions containing them
CA1116605A (en)	1982-01-19	Bis(2-imidazolin-2-ylhydrazone)-9,10-dihydro-9,10- anthracenedicarboxaldehydes
JPS5931492B2 (ja)	1984-08-02	２−（オメガ−アミノアルコキシ）ジフエニルメチルメタン類
JPS6048507B2 (ja)	1985-10-28	２―（ω―アミノアルコキシ）ジフエニルスルフイド類
JPH06726B2 (ja)	1994-01-05	含窒素テルペンアルコ−ル類及びこれを有効成分とする抗アレルギ−剤
JPS62277371A (ja)	1987-12-02	新規なアルキレンジアミン誘導体およびグルタミン酸遮断剤
PL151086B1 (en)	1990-07-31	Process for preparing condensed pyrimidine derivatives