GB1062357A
(en)
|
1965-03-23 |
1967-03-22 |
Pfizer & Co C |
Quinazolone derivatives
|
US4032637A
(en)
|
1972-09-26 |
1977-06-28 |
Sandoz Ltd. |
Method of promoting sleep
|
US4337341A
(en)
|
1976-11-02 |
1982-06-29 |
Eli Lilly And Company |
4a-Aryl-octahydro-1H-2-pyrindines
|
GB8608335D0
(en)
|
1986-04-04 |
1986-05-08 |
Pfizer Ltd |
Pharmaceutically acceptable salts
|
US5453510A
(en)
|
1990-07-13 |
1995-09-26 |
Burroughs Wellcome Co. |
Neuromuscular blocking agents
|
JPH0741461A
(ja)
|
1993-05-27 |
1995-02-10 |
Eisai Co Ltd |
スルホン酸エステル誘導体
|
DK0813525T3
(da)
|
1995-03-10 |
2004-02-16 |
Berlex Lab |
Benzamidinderivater, deres fremstilling og anvendelse som antikoagulanter
|
GB9523675D0
(en)
|
1995-11-20 |
1996-01-24 |
Celltech Therapeutics Ltd |
Chemical compounds
|
GB9619284D0
(en)
|
1996-09-16 |
1996-10-30 |
Celltech Therapeutics Ltd |
Chemical compounds
|
GB9622363D0
(en)
|
1996-10-28 |
1997-01-08 |
Celltech Therapeutics Ltd |
Chemical compounds
|
AU1507199A
(en)
|
1997-12-15 |
1999-07-05 |
Yamanouchi Pharmaceutical Co., Ltd. |
Novel pyrimidine-5-carboxamide derivatives
|
US6303652B1
(en)
|
1998-08-21 |
2001-10-16 |
Hughes Institute |
BTK inhibitors and methods for their identification and use
|
ES2274634T3
(es)
|
1998-08-29 |
2007-05-16 |
Astrazeneca Ab |
Compuestos de pirimidina.
|
IL143023A0
(en)
|
1998-11-10 |
2002-04-21 |
Janssen Pharmaceutica Nv |
Hiv replication inhibiting pyrimidines
|
US6262088B1
(en)
|
1998-11-19 |
2001-07-17 |
Berlex Laboratories, Inc. |
Polyhydroxylated monocyclic N-heterocyclic derivatives as anti-coagulants
|
US6127376A
(en)
|
1998-12-04 |
2000-10-03 |
Berlex Laboratories, Inc. |
Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants
|
GB9828511D0
(en)
|
1998-12-24 |
1999-02-17 |
Zeneca Ltd |
Chemical compounds
|
US6495558B1
(en)
|
1999-01-22 |
2002-12-17 |
Amgen Inc. |
Kinase inhibitors
|
AU2871900A
(en)
|
1999-02-04 |
2000-08-25 |
Millennium Pharmaceuticals, Inc. |
G-protein coupled heptahelical receptor binding compounds and methods of use thereof
|
GB9914258D0
(en)
|
1999-06-18 |
1999-08-18 |
Celltech Therapeutics Ltd |
Chemical compounds
|
US6469168B1
(en)
|
1999-06-29 |
2002-10-22 |
EGIS Gyógyszergyár Rt. |
Piperazinylalkylthiopyrimidine derivatives, pharmaceutical compositions containing the same, and a process for the preparation of the active substance
|
EP1242385B1
(en)
|
1999-12-28 |
2009-11-25 |
Pharmacopeia, Inc. |
Cytokine, especially tnf-alpha, inhibitors
|
AU3704101A
(en)
|
2000-02-17 |
2001-08-27 |
Amgen Inc |
Kinase inhibitors
|
GB0004890D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
GB0004887D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
GB0004888D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
ES2559273T3
(es)
|
2000-05-08 |
2016-02-11 |
Janssen Pharmaceutica Nv |
Profármacos de pirimidinas que inhiben la replicación del VIH
|
GB0016877D0
(en)
|
2000-07-11 |
2000-08-30 |
Astrazeneca Ab |
Chemical compounds
|
CA2417500C
(en)
|
2000-07-28 |
2008-11-18 |
Georgetown University Medical Center |
Erbb-2 selective small molecule kinase inhibitors
|
US6908906B2
(en)
*
|
2001-02-09 |
2005-06-21 |
Sankyo Company, Limited |
Crystalline forms of pyrimidine nucleoside derivative
|
US6881737B2
(en)
|
2001-04-11 |
2005-04-19 |
Amgen Inc. |
Substituted triazinyl acrylamide derivatives and methods of use
|
JO3429B1
(ar)
|
2001-08-13 |
2019-10-20 |
Janssen Pharmaceutica Nv |
مشتقات برميدينات مثبطة فيروس الايدز
|
US6939874B2
(en)
|
2001-08-22 |
2005-09-06 |
Amgen Inc. |
Substituted pyrimidinyl derivatives and methods of use
|
WO2003030909A1
(en)
|
2001-09-25 |
2003-04-17 |
Bayer Pharmaceuticals Corporation |
2- and 4-aminopyrimidines n-substtituded by a bicyclic ring for use as kinase inhibitors in the treatment of cancer
|
US7514445B2
(en)
|
2001-11-01 |
2009-04-07 |
Janssen Pharmaceutica N.V. |
Heteroaryl amines as glycogen synthase kinase 3β inhibitors (GSK3 inhibitors)
|
TWI329105B
(en)
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
AU2003209077A1
(en)
|
2002-02-08 |
2003-09-02 |
Smithkline Beecham Corporation |
Pyrimidine compounds
|
GB0206215D0
(en)
|
2002-03-15 |
2002-05-01 |
Novartis Ag |
Organic compounds
|
US7202033B2
(en)
|
2002-03-21 |
2007-04-10 |
Sunesis Pharmaceuticals, Inc. |
Identification of kinase inhibitors
|
US20040002395A1
(en)
|
2002-06-27 |
2004-01-01 |
Poynor Raymond L. |
Bridge weight for metal wood golf club
|
IL166241A0
(en)
|
2002-07-29 |
2006-01-15 |
Rigel Pharmaceuticals Inc |
Method of treating or preventing autoimmune diseases with 2,4-pyrimidinedinediamine compounds
|
CA2439440A1
(en)
|
2002-09-05 |
2004-03-05 |
Emory University |
Treatment of tuberous sclerosis associated neoplasms
|
AU2002951853A0
(en)
|
2002-10-04 |
2002-10-24 |
Commonwealth Scientific And Industrial Research Organisation |
Crystal structure of erbb2 and uses thereof
|
UA80767C2
(en)
|
2002-12-20 |
2007-10-25 |
Pfizer Prod Inc |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
EA011164B1
(ru)
|
2003-02-07 |
2009-02-27 |
Янссен Фармацевтика Н. В. |
Производные пиримидина для профилактики вич-инфекции
|
JP4634367B2
(ja)
|
2003-02-20 |
2011-02-16 |
スミスクライン ビーチャム コーポレーション |
ピリミジン化合物
|
GB0305929D0
(en)
|
2003-03-14 |
2003-04-23 |
Novartis Ag |
Organic compounds
|
US20050014753A1
(en)
|
2003-04-04 |
2005-01-20 |
Irm Llc |
Novel compounds and compositions as protein kinase inhibitors
|
US20050043233A1
(en)
|
2003-04-29 |
2005-02-24 |
Boehringer Ingelheim International Gmbh |
Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis
|
US7504396B2
(en)
|
2003-06-24 |
2009-03-17 |
Amgen Inc. |
Substituted heterocyclic compounds and methods of use
|
DK1656372T3
(da)
|
2003-07-30 |
2013-07-01 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidindiaminforbindelser til anvendelse til behandling eller forebyggelse af autoimmunsygdomme
|
ES2365223T3
(es)
|
2003-08-07 |
2011-09-26 |
Rigel Pharmaceuticals, Inc. |
Compuestos 2,4-pirimidindiamínicos y usos como agentes antiproliferativos.
|
MXPA06001759A
(es)
|
2003-08-15 |
2006-05-12 |
Novartis Ag |
2,4-pirimidinadiaminas utiles en el tratamiento de enfermedades neoplasticas, desordenes del sistema inmune e inflamatorios.
|
GB0321710D0
(en)
|
2003-09-16 |
2003-10-15 |
Novartis Ag |
Organic compounds
|
CA2538413A1
(en)
|
2003-09-18 |
2005-03-24 |
Novartis Ag |
2,4-di (phenylamino) pyrimidines useful in the treatment of proliferative disorders
|
EP1694652A1
(en)
|
2003-12-19 |
2006-08-30 |
Rigel Pharmaceuticals, Inc. |
Stereoisomers and stereoisomeric mixtures of 1-(2,4-pyrimidinediamino)-2-cyclopentanecarboxamide synthetic intermediates
|
GB2424882B
(en)
|
2004-01-12 |
2008-08-06 |
Cytopia Res Pty Ltd |
Selective kinase inhibitors
|
EP1711467A2
(en)
|
2004-01-16 |
2006-10-18 |
Wyeth |
Quinoline intermediates of receptor tyrosine kinase inhibitors and the synthesis thereof
|
CA2557794A1
(en)
|
2004-03-15 |
2005-10-06 |
Eli Lilly And Company |
Opioid receptor antagonists
|
WO2005105988A2
(en)
|
2004-04-28 |
2005-11-10 |
Vertex Pharmaceuticals Incorporated |
Crystal structure of human jak3 kinase domain complex and binding pockets thereof
|
EP1763514A2
(en)
|
2004-05-18 |
2007-03-21 |
Rigel Pharmaceuticals, Inc. |
Cycloalkyl substituted pyrimidinediamine compounds and their uses
|
EP1598343A1
(de)
|
2004-05-19 |
2005-11-23 |
Boehringer Ingelheim International GmbH |
2-Arylaminopyrimidine als PLK Inhibitoren
|
EP1766068A4
(en)
|
2004-06-04 |
2010-03-03 |
Genentech Inc |
EGFR Mutations
|
US7521457B2
(en)
|
2004-08-20 |
2009-04-21 |
Boehringer Ingelheim International Gmbh |
Pyrimidines as PLK inhibitors
|
GB0419161D0
(en)
|
2004-08-27 |
2004-09-29 |
Novartis Ag |
Organic compounds
|
EP1796673A2
(en)
|
2004-09-23 |
2007-06-20 |
Reddy US Therapeutics, Inc. |
Novel pyrimidine compounds, process for their preparation and compositions containing them
|
MX2007003798A
(es)
|
2004-09-30 |
2007-04-23 |
Tibotec Pharm Ltd |
Pirimidinas 5-sustituidas con carbociclos o heterociclos inhibidoras del vih.
|
WO2006044457A1
(en)
|
2004-10-13 |
2006-04-27 |
Wyeth |
N-benzenesulfonyl substituted anilino-pyrimidine analogs
|
EP1805208A2
(en)
|
2004-10-20 |
2007-07-11 |
Proteolix, Inc. |
Labeled compounds for proteasome inhibition
|
US7919487B2
(en)
|
2004-11-10 |
2011-04-05 |
Synta Pharmaceuticals Corporation |
Heteroaryl compounds
|
GB2420559B
(en)
|
2004-11-15 |
2008-08-06 |
Rigel Pharmaceuticals Inc |
Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses
|
ES2380550T3
(es)
|
2004-11-24 |
2012-05-16 |
Rigel Pharmaceuticals, Inc. |
Compuestos de espiro-2,4-pirimidindiamina y sus usos
|
MY169441A
(en)
|
2004-12-08 |
2019-04-11 |
Janssen Pharmaceutica Nv |
2,4, (4,6) pyrimidine derivatives
|
US8211929B2
(en)
|
2004-12-30 |
2012-07-03 |
Exelixis, Inc. |
Pyrimidine derivatives as kinase modulators and method of use
|
EP1856053A1
(en)
|
2005-01-14 |
2007-11-21 |
Millennium Pharmaceuticals, Inc. |
Cinnamide and hydrocinnamide derivatives with raf-kinase inhibitory activity
|
US7449458B2
(en)
|
2005-01-19 |
2008-11-11 |
Rigel Pharmaceuticals, Inc. |
Prodrugs of 2,4-pyrimidinediamine compounds and their uses
|
EP2505591A1
(en)
|
2005-02-11 |
2012-10-03 |
Memorial Sloan-Kettering Cancer Center |
Methods and compositions for detecting a drug resistant EGFR mutant
|
JP2008533166A
(ja)
|
2005-03-16 |
2008-08-21 |
ターゲジェン インコーポレーティッド |
ピリミジン化合物および使用法
|
DE102005016634A1
(de)
|
2005-04-12 |
2006-10-19 |
Merck Patent Gmbh |
Neuartige Aza-Hetercyclen als Kinase-Inhibitoren
|
US20060270694A1
(en)
|
2005-05-03 |
2006-11-30 |
Rigel Pharmaceuticals, Inc. |
JAK kinase inhibitors and their uses
|
WO2006124874A2
(en)
|
2005-05-12 |
2006-11-23 |
Kalypsys, Inc. |
Inhibitors of b-raf kinase
|
US20070032493A1
(en)
|
2005-05-26 |
2007-02-08 |
Synta Pharmaceuticals Corp. |
Method for treating B cell regulated autoimmune disorders
|
WO2006128129A2
(en)
|
2005-05-26 |
2006-11-30 |
Synta Pharmaceuticals Corp. |
Method for treating cancer
|
WO2006129100A1
(en)
|
2005-06-03 |
2006-12-07 |
Glaxo Group Limited |
Novel compounds
|
US20070203161A1
(en)
|
2006-02-24 |
2007-08-30 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
KR101312225B1
(ko)
|
2005-06-08 |
2013-09-26 |
리겔 파마슈티칼스, 인크. |
Jak 경로의 억제를 위한 조성물 및 방법
|
CA2626742A1
(en)
|
2005-10-21 |
2007-04-26 |
Exelixis, Inc. |
Pyrazolo-pyrimidines as casein kinase ii (ck2) modulators
|
JP5191391B2
(ja)
|
2005-11-01 |
2013-05-08 |
ターゲジェン インコーポレーティッド |
キナーゼのビ−アリールメタ−ピリミジン阻害剤
|
WO2007056151A2
(en)
|
2005-11-03 |
2007-05-18 |
Irm Llc |
Protein kinase inhbitors
|
US7713987B2
(en)
|
2005-12-06 |
2010-05-11 |
Rigel Pharmaceuticals, Inc. |
Pyrimidine-2,4-diamines and their uses
|
US20080318989A1
(en)
|
2005-12-19 |
2008-12-25 |
Burdick Daniel J |
Pyrimidine Kinase Inhibitors
|
TW200736232A
(en)
|
2006-01-26 |
2007-10-01 |
Astrazeneca Ab |
Pyrimidine derivatives
|
KR20080110998A
(ko)
|
2006-01-30 |
2008-12-22 |
엑셀리시스, 인코포레이티드 |
Jak2 조절자로서 4아릴2아미노피리미딘 또는 4아릴2아미노알킬피리미딘 및 이들을 포함하는 약제학적 조성물
|
DK1984357T3
(da)
|
2006-02-17 |
2014-01-13 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidindiaminforbindelser til behandling eller forebyggelse af autoimmunsygdomme
|
CA2642229C
(en)
|
2006-02-24 |
2015-05-12 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
RU2480464C2
(ru)
|
2006-03-30 |
2013-04-27 |
Тиботек Фармасьютикалз Лтд. |
5-амидо-замещенные пиримидины, ингибирующие вич
|
CN101410394B
(zh)
|
2006-03-30 |
2012-02-08 |
泰博特克药品有限公司 |
抑制人免疫缺陷病毒的5-(羟基亚甲基和氨基亚甲基)取代的嘧啶
|
US7560588B2
(en)
|
2006-04-27 |
2009-07-14 |
Intezyne Technologies, Inc. |
Poly(ethylene glycol) containing chemically disparate endgroups
|
GB0608386D0
(en)
|
2006-04-27 |
2006-06-07 |
Senexis Ltd |
Compounds
|
DE102006027156A1
(de)
|
2006-06-08 |
2007-12-13 |
Bayer Schering Pharma Ag |
Sulfimide als Proteinkinaseinhibitoren
|
US8222256B2
(en)
|
2006-07-05 |
2012-07-17 |
Exelixis, Inc. |
Methods of using IGFIR and ABL kinase modulators
|
AU2007276369A1
(en)
|
2006-07-21 |
2008-01-24 |
Novartis Ag |
2, 4 -di (arylaminio) -pyrimidine-5-carboxamide compounds as JAK kinases inhibitors
|
DE102006041382A1
(de)
|
2006-08-29 |
2008-03-20 |
Bayer Schering Pharma Ag |
Carbamoyl-Sulfoximide als Proteinkinaseinhibitoren
|
SI2526934T1
(sl)
|
2006-09-22 |
2016-04-29 |
Pharmacyclics Llc |
Inhibitorji Bruton tirozin kinaze
|
DE602007012363D1
(de)
|
2006-10-19 |
2011-03-17 |
Rigel Pharmaceuticals Inc |
2,4-pyridimediamon-derivate als hemmer von jak-kinasen zur behandlung von autoimmunerkrankungen
|
WO2008054827A2
(en)
|
2006-11-03 |
2008-05-08 |
Pharmacyclics, Inc. |
Bruton's tyrosine kinase activity probe and method of using
|
US8163902B2
(en)
|
2006-11-21 |
2012-04-24 |
Rigel Pharmaceuticals, Inc. |
Prodrugs of 2,4-pyrimidinediamine compounds and their uses
|
CA2671744C
(en)
|
2006-12-08 |
2012-08-28 |
Irm Llc |
Compounds and compositions as protein kinase inhibitors
|
AU2007337088A1
(en)
|
2006-12-19 |
2008-07-03 |
Genentech, Inc. |
Pyrimidine kinase inhibitors
|
EP1939185A1
(de)
|
2006-12-20 |
2008-07-02 |
Bayer Schering Pharma Aktiengesellschaft |
Neuartige Hetaryl-Phenylendiamin-Pyrimidine als Proteinkinaseinhibitoren zur Behandlung von Krebs
|
BRPI0722079B8
(pt)
|
2006-12-29 |
2021-05-25 |
Janssen R & D Ireland |
pirimidinas 5,6-substituídas inibidoras de hiv e composição farmacêutica que as compreende
|
CN101573343B
(zh)
|
2006-12-29 |
2016-02-24 |
爱尔兰詹森科学公司 |
抑制人免疫缺陷病毒的6-取代的嘧啶
|
AR065015A1
(es)
|
2007-01-26 |
2009-05-13 |
Smithkline Beecham Corp |
Derivados de antranilamida, composiciones farmaceuticas que los contienen, y usos para el tratamiento del cancer
|
AU2008210266B2
(en)
|
2007-01-31 |
2013-09-05 |
Ym Biosciences Australia Pty Ltd |
Thiopyrimidine-based compounds and uses thereof
|
JP4221470B2
(ja)
|
2007-02-01 |
2009-02-12 |
トヨタ自動車株式会社 |
電動車両制御装置及び電動車両制御方法
|
DE102007010801A1
(de)
|
2007-03-02 |
2008-09-04 |
Bayer Cropscience Ag |
Diaminopyrimidine als Fungizide
|
CA2681250A1
(en)
|
2007-03-20 |
2008-09-25 |
Smithkline Beecham Corporation |
Chemical compounds
|
CN101677554A
(zh)
|
2007-03-20 |
2010-03-24 |
史密丝克莱恩比彻姆公司 |
化合物
|
US7947698B2
(en)
|
2007-03-23 |
2011-05-24 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the JAK pathway
|
WO2008118823A2
(en)
|
2007-03-26 |
2008-10-02 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
US20120065201A1
(en)
|
2007-03-28 |
2012-03-15 |
Pharmacyclics, Inc. |
Inhibitors of bruton's tyrosine kinase
|
US8809273B2
(en)
|
2007-03-28 |
2014-08-19 |
Pharmacyclics, Inc. |
Inhibitors of Bruton's tyrosine kinase
|
US8242271B2
(en)
|
2007-06-04 |
2012-08-14 |
Avila Therapeutics, Inc. |
Heterocyclic compounds and uses thereof
|
CA2693594A1
(en)
|
2007-07-17 |
2009-01-22 |
Rigel Pharmaceuticals, Inc. |
Cyclic amine substituted pyrimidinediamines as pkc inhibitors
|
WO2009017838A2
(en)
|
2007-08-01 |
2009-02-05 |
Exelixis, Inc. |
Combinations of jak-2 inhibitors and other agents
|
BRPI0815979A2
(pt)
|
2007-08-28 |
2017-06-13 |
Irm Llc |
compostos e composições com inibidores de quinase, bem como uso dos mesmos
|
WO2009032694A1
(en)
|
2007-08-28 |
2009-03-12 |
Dana Farber Cancer Institute |
Amino substituted pyrimidine, pyrollopyridine and pyrazolopyrimidine derivatives useful as kinase inhibitors and in treating proliferative disorders and diseases associated with angiogenesis
|
US20090088371A1
(en)
|
2007-08-28 |
2009-04-02 |
Rigel Pharmaceuticals, Inc. |
Combination therapy with syk kinase inhibitor
|
EP2214486A4
(en)
|
2007-10-19 |
2011-03-09 |
Avila Therapeutics Inc |
HETEROARYL COMPOUNDS AND ITS USES
|
US7989465B2
(en)
|
2007-10-19 |
2011-08-02 |
Avila Therapeutics, Inc. |
4,6-disubstituted pyrimidines useful as kinase inhibitors
|
US20110028405A1
(en)
|
2007-12-20 |
2011-02-03 |
Richard John Harrison |
Sulfamides as zap-70 inhibitors
|
BRPI0907724B8
(pt)
|
2008-02-22 |
2021-05-25 |
Rigel Pharmaceuticals Inc |
uso de n4-(2,2-dimetil-4-[(di-hidrogeno-fosfonóxi)metil]-3-oxo-5-pirido[1,4]oxazin-6-il)-5-fluoro-n2-(3,4,5-trimetoxifenil)-2,4-pirimidinadiamina ou um sal deste
|
US20110098288A1
(en)
|
2008-03-11 |
2011-04-28 |
Jeremy Major |
Sulfonamides as zap-70 inhibitors
|
US8205348B2
(en)
|
2008-03-19 |
2012-06-26 |
Zashiki-Warashi Manufacturing Inc. |
Tile spacer and holder therefor
|
CL2009000600A1
(es)
|
2008-03-20 |
2010-05-07 |
Bayer Cropscience Ag |
Uso de compuestos de diaminopirimidina como agentes fitosanitarios; compuestos de diaminopirimidina; su procedimiento de preparacion; agente que los contiene; procedimiento para la preparacion de dicho agente; y procedimiento para combatir plagas de animales y/u hongos dañinos patogenos de plantas.
|
WO2009127642A2
(en)
|
2008-04-15 |
2009-10-22 |
Cellzome Limited |
Use of lrrk2 inhibitors for neurodegenerative diseases
|
US8138339B2
(en)
|
2008-04-16 |
2012-03-20 |
Portola Pharmaceuticals, Inc. |
Inhibitors of protein kinases
|
JP2011518836A
(ja)
|
2008-04-24 |
2011-06-30 |
インサイト・コーポレイション |
大環状化合物およびそれらのキナーゼ阻害剤としての使用
|
HUE035029T2
(en)
|
2008-05-21 |
2018-03-28 |
Ariad Pharma Inc |
Kinase inhibitor phosphorus derivatives
|
TWI546290B
(zh)
*
|
2008-06-27 |
2016-08-21 |
賽基艾維洛米斯研究股份有限公司 |
雜芳基化合物及其用途
|
US8338439B2
(en)
|
2008-06-27 |
2012-12-25 |
Celgene Avilomics Research, Inc. |
2,4-disubstituted pyrimidines useful as kinase inhibitors
|
AU2009270856B2
(en)
|
2008-07-16 |
2013-07-25 |
Pharmacyclics Llc |
Inhibitors of Bruton's tyrosine kinase for the treatment of solid tumors
|
EP2331512A1
(de)
|
2008-09-03 |
2011-06-15 |
Bayer CropScience AG |
Alkoxy- und alkylthio-substituierte anilinopyrimidine
|
US20110245156A1
(en)
|
2008-12-09 |
2011-10-06 |
Cytokine Pharmasciences, Inc. |
Novel antiviral compounds, compositions, and methods of use
|
SG172927A1
(en)
|
2009-01-15 |
2011-08-29 |
Hoffmann La Roche |
Antibodies against human epo receptor
|
EP2414337B1
(en)
|
2009-04-03 |
2013-05-01 |
Cellzome GmbH |
Methods for the identification of kinase interacting molecules and for the purification of kinase proteins
|
ES2659725T3
(es)
*
|
2009-05-05 |
2018-03-19 |
Dana-Farber Cancer Institute, Inc. |
Inhibidores de EGFR y procedimiento de tratamiento de trastornos
|
PL2428508T3
(pl)
|
2009-05-08 |
2016-05-31 |
Astellas Pharma Inc |
Diaminoheterocykliczny związek karboksyamidowy
|
EP2443095A1
(en)
|
2009-06-18 |
2012-04-25 |
Cellzome Limited |
Sulfonamides and sulfamides as zap-70 inhibitors
|
US7718662B1
(en)
|
2009-10-12 |
2010-05-18 |
Pharmacyclics, Inc. |
Pyrazolo-pyrimidine inhibitors of bruton's tyrosine kinase
|
WO2011079231A1
(en)
|
2009-12-23 |
2011-06-30 |
Gatekeeper Pharmaceutical, Inc. |
Compounds that modulate egfr activity and methods for treating or preventing conditions therewith
|
WO2011140338A1
(en)
|
2010-05-05 |
2011-11-10 |
Gatekeeper Pharmaceuticals, Inc. |
Compounds that modulate egfr activity and methods for treating or preventing conditions therewith
|
US20120071497A1
(en)
|
2010-06-03 |
2012-03-22 |
Pharmacyclics, Inc. |
Methods of treating abc-dlbcl using inhibitors of bruton's tyrosine kinase
|
MX342405B
(es)
|
2010-06-03 |
2016-09-28 |
Pharmacyclics Inc |
El uso de inhibidores de la tirosina quinasa de bruton (btk).
|
WO2011153553A2
(en)
|
2010-06-04 |
2011-12-08 |
The Regents Of The University Of California |
Methods and compositions for kinase inhibition
|
BR112013003388A2
(pt)
|
2010-08-10 |
2016-07-12 |
Celgene Avilomics Res Inc |
sal de besilato de um inibidor de btk
|
WO2012061415A1
(en)
|
2010-11-01 |
2012-05-10 |
Portola Pharmaceuticals, Inc. |
Oxypyrimidines as syk modulators
|
ES2635713T3
(es)
|
2010-11-01 |
2017-10-04 |
Celgene Car Llc |
Compuestos de heteroarilo y usos de los mismos
|
WO2012061299A1
(en)
|
2010-11-01 |
2012-05-10 |
Avila Therapeutics, Inc. |
Heterocyclic compounds and uses thereof
|
EP2637502B1
(en)
|
2010-11-10 |
2018-01-10 |
Celgene CAR LLC |
Mutant-selective egfr inhibitors and uses thereof
|
CN103501612B
(zh)
|
2011-05-04 |
2017-03-29 |
阿里亚德医药股份有限公司 |
抑制表皮生长因子受体导致的癌症中细胞增殖的化合物
|
US9580427B2
(en)
|
2011-05-17 |
2017-02-28 |
The Regents Of The University Of California |
Kinase inhibitors
|
BR112014022789B1
(pt)
|
2012-03-15 |
2022-04-19 |
Celgene Car Llc |
Formas sólidas de um inibidor de quinase de receptor do fator de crescimento epidérmico, composição farmacêutica e usos do mesmo
|
CA2866857C
(en)
|
2012-03-15 |
2021-03-09 |
Celgene Avilomics Research, Inc. |
Salts of an epidermal growth factor receptor kinase inhibitor
|
KR20150080592A
(ko)
|
2012-11-02 |
2015-07-09 |
파마시클릭스, 인코포레이티드 |
Tec 패밀리 키나제 억제제 애쥬번트 요법
|
US20160074399A1
(en)
|
2013-05-06 |
2016-03-17 |
Clovis Oncology, Inc. |
Salts of an Epidermal Growth Factor Receptor Kinase Inhibitor
|