NO2007009I1 - Valsartan (N-(1-oksopentyl)-N-2[2'-(1-tetrazol-5-yl)metyl-valine amlodtpin(2-](2-aminoetoksy)metvll-4-(2-klorfenvll-l.4-dihvdro-6-metvl-3.5-nvridinkarboksvl sure-3-etvl-5-metvl ester - Google Patents

Valsartan (N-(1-oksopentyl)-N-2[2'-(1-tetrazol-5-yl)metyl-valine amlodtpin(2-](2-aminoetoksy)metvll-4-(2-klorfenvll-l.4-dihvdro-6-metvl-3.5-nvridinkarboksvl sure-3-etvl-5-metvl ester

Info

Publication number
NO2007009I1
NO2007009I1 NO2007009C NO2007009C NO2007009I1 NO 2007009 I1 NO2007009 I1 NO 2007009I1 NO 2007009 C NO2007009 C NO 2007009C NO 2007009 C NO2007009 C NO 2007009C NO 2007009 I1 NO2007009 I1 NO 2007009I1
Authority
NO
Norway
Prior art keywords
methyl
hydrocarbon
tetrazol
carboxy
cycloaliphatic
Prior art date
Application number
NO2007009C
Other languages
English (en)
Other versions
NO2007009I2 (no
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25684817&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO2007009(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO2007009I1 publication Critical patent/NO2007009I1/no
Publication of NO2007009I2 publication Critical patent/NO2007009I2/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/54—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Magnetic Record Carriers (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)
  • Pyrrole Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
NO2007009C 1990-02-19 1991-02-18 Valsartan og Amlodipin NO2007009I2 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH51890 1990-02-19
CH223490 1990-07-05

Publications (2)

Publication Number Publication Date
NO2007009I1 true NO2007009I1 (no) 2007-07-23
NO2007009I2 NO2007009I2 (no) 2010-09-13

Family

ID=25684817

Family Applications (5)

Application Number Title Priority Date Filing Date
NO910630A NO304023B1 (no) 1990-02-19 1991-02-18 AnalogifremgangsmÕte for fremstilling av terapeutisk aktive acylforbindelser
NO1999001C NO1999001I2 (no) 1990-02-19 1991-02-18 Analogifremgangsmaate for fremstilling av terapeutisk aktive acylforbindelser
NO2007009C NO2007009I2 (no) 1990-02-19 1991-02-18 Valsartan og Amlodipin
NO1998024C NO1998024I1 (no) 1990-02-19 1998-10-21 Valsartan
NO2010008C NO2010008I1 (no) 1990-02-19 2010-04-14 Valsartan, amlodipin, hydroklortiazid og farmasøytiske akseptable salter derav

Family Applications Before (2)

Application Number Title Priority Date Filing Date
NO910630A NO304023B1 (no) 1990-02-19 1991-02-18 AnalogifremgangsmÕte for fremstilling av terapeutisk aktive acylforbindelser
NO1999001C NO1999001I2 (no) 1990-02-19 1991-02-18 Analogifremgangsmaate for fremstilling av terapeutisk aktive acylforbindelser

Family Applications After (2)

Application Number Title Priority Date Filing Date
NO1998024C NO1998024I1 (no) 1990-02-19 1998-10-21 Valsartan
NO2010008C NO2010008I1 (no) 1990-02-19 2010-04-14 Valsartan, amlodipin, hydroklortiazid og farmasøytiske akseptable salter derav

Country Status (26)

Country Link
US (2) US5399578A (no)
EP (1) EP0443983B1 (no)
JP (1) JP2749458B2 (no)
KR (1) KR0171409B1 (no)
AT (1) ATE134624T1 (no)
AU (1) AU644844B2 (no)
CA (2) CA2232775C (no)
CY (2) CY1978A (no)
DE (4) DE19675036I2 (no)
DK (1) DK0443983T3 (no)
ES (1) ES2084801T3 (no)
FI (2) FI107921B (no)
GR (1) GR3019155T3 (no)
HK (1) HK219996A (no)
HU (2) HU219343B (no)
IE (1) IE71155B1 (no)
IL (1) IL97219A (no)
LU (4) LU90100I2 (no)
LV (1) LV5773B4 (no)
NL (3) NL970001I2 (no)
NO (5) NO304023B1 (no)
NZ (1) NZ237126A (no)
PH (1) PH30484A (no)
PT (1) PT96799B (no)
SA (1) SA93140130A (no)
UY (1) UY23835A1 (no)

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