LU90712I2 - Mal-ate de 5-(4-(n-m-thyl-n-(2-pyriddyl)amino)-thoxy)benzyl)) thiazolidinedione-2,4 dione ou ses sels pharmaceutiquement acceptables - Google Patents

Mal-ate de 5-(4-(n-m-thyl-n-(2-pyriddyl)amino)-thoxy)benzyl)) thiazolidinedione-2,4 dione ou ses sels pharmaceutiquement acceptables

Info

Publication number: LU90712I2
Authority: LU; Luxembourg
Prior art keywords: pyriddyl; thoxy; thiazolidinedione; thyl; dione
Prior art date: 1992-09-05

Application number

LU90712C

Other languages

English (en)

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-09-05

Filing date

2001-01-10

Publication date

2001-03-12

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10721461&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU90712(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-01-10 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2001-03-12 Publication of LU90712I2 publication Critical patent/LU90712I2/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Child & Adolescent Psychology (AREA)
Nutrition Science (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Thiazole And Isothizaole Compounds (AREA)

LU90712C 1992-09-05 2001-01-10 Mal-ate de 5-(4-(n-m-thyl-n-(2-pyriddyl)amino)-thoxy)benzyl)) thiazolidinedione-2,4 dione ou ses sels pharmaceutiquement acceptables LU90712I2 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB929218830A GB9218830D0 (en)	1992-09-05	1992-09-05	Novel compounds
PCT/GB1993/001853 WO1994005659A1 (fr)	1992-09-05	1993-09-01	Derives substitues de la thiazolidenedione

Publications (1)

Publication Number	Publication Date
LU90712I2 true LU90712I2 (fr)	2001-03-12

Family

ID=10721461

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LU90712C LU90712I2 (fr)	1992-09-05	2001-01-10	Mal-ate de 5-(4-(n-m-thyl-n-(2-pyriddyl)amino)-thoxy)benzyl)) thiazolidinedione-2,4 dione ou ses sels pharmaceutiquement acceptables

Country Status (38)

Country	Link
US (1)	US5910592A (fr)
EP (2)	EP0960883A1 (fr)
JP (5)	JP2828777B2 (fr)
KR (3)	KR20030097596A (fr)
CN (4)	CN1040323C (fr)
AP (1)	AP513A (fr)
AT (1)	ATE182147T1 (fr)
AU (1)	AU674880B2 (fr)
BR (1)	BR1100916A (fr)
CA (2)	CA2143849C (fr)
CY (1)	CY2138B1 (fr)
CZ (2)	CZ287473B6 (fr)
DE (2)	DE10199002I2 (fr)
DK (1)	DK0658161T3 (fr)
ES (1)	ES2133410T3 (fr)
FI (2)	FI106263B (fr)
GB (1)	GB9218830D0 (fr)
GR (1)	GR3030794T3 (fr)
HK (1)	HK1012363A1 (fr)
HU (2)	HU224212B1 (fr)
IL (1)	IL106904A (fr)
LU (1)	LU90712I2 (fr)
MA (1)	MA22970A1 (fr)
MX (1)	MX9305397A (fr)
MY (1)	MY111190A (fr)
NL (1)	NL300035I2 (fr)
NO (4)	NO303016B1 (fr)
NZ (1)	NZ255505A (fr)
PL (1)	PL173725B1 (fr)
RU (3)	RU2128179C1 (fr)
SA (1)	SA93140245B1 (fr)
SG (2)	SG48302A1 (fr)
SI (1)	SI9300452B (fr)
SK (1)	SK280777B6 (fr)
TW (1)	TW385309B (fr)
UA (1)	UA41901C2 (fr)
WO (1)	WO1994005659A1 (fr)
ZA (1)	ZA936509B (fr)

Families Citing this family (108)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9308487D0 (en) *	1993-04-23	1993-06-09	Smithkline Beecham Plc	Novel compounds
ZA973850B (en) *	1996-05-06	1997-12-02	Reddy Research Foundation	Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them.
US5801173A (en) *	1996-05-06	1998-09-01	Dr. Reddy's Research Foundation	Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5889032A (en) *	1996-05-06	1999-03-30	Dr. Reddy's Research Foundation	Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5919782A (en) *	1996-05-06	1999-07-06	Dr. Reddy's Research Foundation	Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US6372750B2 (en)	1996-07-01	2002-04-16	Dr. Reddy's Research Foundation	Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
BR9711098B1 (pt) *	1996-07-01	2011-10-04		compostos heterocìclicos, processo para sua preparação e composições farmacêuticas contendo os mesmos e seu uso no tratamento de diabetes e doenças relacionadas.
USRE39266E1 (en) *	1996-07-01	2006-09-05	Dr. Reddy's Laboratories, Limited	Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US5885997A (en) *	1996-07-01	1999-03-23	Dr. Reddy's Research Foundation	Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6114526A (en)	1996-07-01	2000-09-05	Dr. Reddy's Research Foundation	Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
CA2260044A1 (fr) *	1996-07-12	1998-01-22	Stephen Alistair Smith	Nouveau traitement contre la resistance a la leptine
GB9711683D0 (en) *	1997-06-05	1997-08-06	Smithkline Beecham Plc	Composition
WO1998057649A1 (fr) *	1997-06-18	1998-12-23	Smithkline Beecham Plc	Traitement du diabete a l'aide de thiazolidinedione et de sulfonyluree
SI0996444T1 (sl) *	1997-06-18	2007-08-31	Smithkline Beecham Plc	Zdravljenje diabetesa s tiazolidindionom in metforminom
GB9715306D0 (en) *	1997-07-18	1997-09-24	Smithkline Beecham Plc	Novel method of treatment
US20010031776A1 (en) *	1997-10-13	2001-10-18	Smithkline Beecham P.L.C.	Use of thiazolidinediones for the treatment of hyperglycaemia
US20020006939A1 (en) *	1997-10-13	2002-01-17	Smithkline Beecham P.L.C.	Use of thiazolidinediones for the treatment of hyperglycaemia
GB9721692D0 (en) *	1997-10-13	1997-12-10	Smithkline Beecham Plc	Novel treatment
GB9721693D0 (en) *	1997-10-13	1997-12-10	Smithkline Beecham Plc	Novel treatment
GB9723295D0 (en) *	1997-11-04	1998-01-07	Smithkline Beecham Plc	Novel process
US7091359B2 (en)	1997-11-04	2006-08-15	Smithkline Beecham Plc	Process for the preparation of thiazolidinedione derivatives
GB9726563D0 (en) *	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
GB9726568D0 (en) *	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
AU770817B2 (en) *	1997-12-16	2004-03-04	Smithkline Beecham Plc	5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl) thiazolidine-2,dione,maleic acid salt, hydrate as pharmaceutical
US20020137940A1 (en) *	1997-12-16	2002-09-26	Smithkline Beecham P.L.C.	5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
GB9726566D0 (en) *	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
US6664278B2 (en)	1997-12-16	2003-12-16	Smithkline Beecham P.L.C.	Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
AU774613B2 (en) *	1997-12-16	2004-07-01	Smithkline Beecham Plc	Hydrate of 5-(4-(2- (N-methyl-N- (2-pyridil)amino) ethoxy)benzyl) thiazolidine-2,4-dione maleic acid salt
US6613785B2 (en)	1998-07-21	2003-09-02	Smithkline Beecham Plc	Use of glucose uptake enhancer for reducing post-ischemic injury of the heart
MA26662A1 (fr) *	1998-07-21	2004-12-20	Smithkline Beecham Plc	Derives de thiazolidinedione, compositions pharmaceutiques les contenant et leur utilisation
OA11579A (en) *	1998-07-21	2004-06-01	Smithkline Beecham Plc	Use of glucose uptake enhancer for reducing apoptosis.
US20030153607A1 (en) *	1998-11-12	2003-08-14	Smithkline Beecham P.L.C.	Novel composition and use
AR023700A1 (es) *	1998-11-12	2002-09-04	Smithkline Beecham Plc	Un procedimiento para preparar una composicion farmaceutica que comprende un sensibilizador de insulina
ID28783A (id)	1998-11-12	2001-07-05	Smithkline Beecham Plc	Komposisi farmasi untuk pelepasan termodifikasi dari pemeka insulin dan zat antidiabetes lain
GB9824893D0 (en) *	1998-11-12	1999-01-06	Smithkline Beckman Corp	Novel method of treatment
US20040102486A1 (en) *	1998-11-12	2004-05-27	Smithkline Beecham Corporation	Novel method of treatment
GB9909075D0 (en) *	1999-04-20	1999-06-16	Smithkline Beecham Plc	Novel pharmaceutical
GB9909041D0 (en) *	1999-04-20	1999-06-16	Smithkline Beecham Plc	Novel pharmaceutical
BR0009935A (pt) *	1999-04-23	2002-04-16	Smithkline Beecham Plc	Produto farmacêutico
DE60037602T2 (de)	1999-04-23	2009-01-08	Smithkline Beecham P.L.C., Brentford	Herstellung einer polymorphen Form eines Thiazolidindionderivates
SK286427B6 (sk) *	1999-04-23	2008-09-05	Smithkline Beecham Plc	Polymorfná forma soli 5-[4-[2-(N-metyl-N-(2- pyridyl)amino)etoxy]benzyl]tiazolidín-2,4-diónu s kyselinou maleínovu, spôsob jej prípravy, farmaceutický prostriedok s jej obsahom a jej použitie
US20040248945A1 (en)	1999-04-23	2004-12-09	Smithkline Beecham P.L.C.	Thiazolidinedione derivative and its use as antidiabetic
TR200200438T2 (tr) *	1999-08-17	2002-05-21	Smithkline Beecham P.L.C.	Tiazolidindion türevleri içeren farmasötik terkipler ve bu terkipleri hazırlama prosesi.
MY125516A (en) *	1999-11-16	2006-08-30	Smithkline Beecham Plc	Novel composition based on thiazolidinedione and metformin and use
GB0006133D0 (en) *	2000-03-14	2000-05-03	Smithkline Beecham Plc	Novel pharmaceutical
GB0014005D0 (en) *	2000-06-08	2000-08-02	Smithkline Beecham Plc	Novel pharmaceutical
GB0014006D0 (en) *	2000-06-08	2000-08-02	Smithkline Beecham Plc	Novel pharmaceutical
EA200300028A1 (ru) *	2000-06-16	2003-04-24	Смитклайн Бичам Плс	Лечение и профилактика состояний, ассоциированных с сердечной инсулинорезистентностью
GB0014969D0 (en)	2000-06-19	2000-08-09	Smithkline Beecham Plc	Novel method of treatment
GB0019226D0 (en) *	2000-08-04	2000-09-27	Smithkline Beecham Plc	Novel pharmaceutical
GB0019223D0 (en) *	2000-08-04	2000-09-27	Smithkline Beecham Plc	Novel pharmaceutical
AU2005229687B2 (en) *	2000-08-04	2008-03-13	Smithkline Beecham P.L.C.	Tartrate salts of thiazolidinedione derivative
GB0019224D0 (en) *	2000-08-04	2000-09-27	Smithkline Beecham Plc	Novel pharmaceutical
AU2005229688B2 (en) *	2000-08-04	2008-04-03	Smithkline Beecham P.L.C.	Tartrate salts of thiazolidinedione derivative
GB0019228D0 (en) *	2000-08-04	2000-09-27	Smithkline Beecham Plc	Novel pharmaceutical
GB0021784D0 (en) *	2000-09-05	2000-10-18	Smithkline Beecham Plc	Novel pharmaceutical
GB0021785D0 (en) *	2000-09-05	2000-10-18	Smithkline Beecham Plc	Novel Pharmaceutical
GB0021865D0 (en) *	2000-09-06	2000-10-18	Smithkline Beecham Plc	Novel pharmaceutical
GB0021978D0 (en)	2000-09-07	2000-10-25	Smithkline Beecham Plc	Novel pharmaceutical
PL360661A1 (en) *	2000-09-26	2004-09-20	Dr.Reddy's Research Foundation	Novel polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl)amino]ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation
US7241895B2 (en)	2000-09-26	2007-07-10	Dr. Reddy's Laboratories Limited	Polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl)amino[ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation
GB0023971D0 (en) *	2000-09-29	2000-11-15	Smithkline Beecham Plc	Novel pharmaceutical
ES2270955T3 (es) *	2000-12-22	2007-04-16	Smithkline Beecham Plc	Sal mesilato de 5-(4-(2-(n-metil-n-(2-piridil)amino)etoxi)bencil)tiazolidina-2,4-diona.
WO2002051823A1 (fr)	2000-12-26	2002-07-04	Torrent Pharmaceuticals Ltd	Procede de preparation de maleate de rosiglitazone
GB0127805D0 (en)	2001-11-20	2002-01-09	Smithkline Beecham Plc	Pharmaceutical composition
ES2266593T3 (es) *	2001-11-21	2007-03-01	Smithkline Beecham Plc	Edisilatos de rosiglitazona y su uso como antidiabeticos.
CN100390170C (zh) *	2001-11-21	2008-05-28	史密斯克莱·比奇曼公司	5－(4－(2－(n－甲基－n－(2－吡啶基)氨基)乙氧基)苄基)噻唑烷－2,4－二酮苯磺酸盐，它的制备方法,其多晶型物ⅰ、ⅱ和ⅲ和它作为药物活性成分的用途
GB0129851D0 (en) *	2001-12-13	2002-01-30	Smithkline Beecham Plc	Novel compounds
AU2002350965A1 (en) *	2001-12-13	2003-06-23	Smithkline Beecham Plc	Toluenesulfonate hydrates of a thiazolidinedione derivative
WO2003050116A1 (fr) *	2001-12-13	2003-06-19	Smithkline Beecham Plc	Sel d'acide 10-camphorsulphonique de 5(-4-(2-(n-methyl-n-(2-pyridil)amino)ethoxy)benzyl)thiazolidine-2,4-dione et son utilisation contre le diabete sucre
GB0129876D0 (en) *	2001-12-13	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
GB0129872D0 (en) *	2001-12-13	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
GB0129871D0 (en) *	2001-12-13	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
AU2002352479A1 (en) *	2001-12-20	2003-07-09	Smithkline Beecham Plc	5- (4- (2- (n-methyl-n- (2-pyridyl) amino) ethoxy) benzyl) thiazolidine-2, 4-dione malic acid salt and use against diabetes mellitus
GB0130510D0 (en) *	2001-12-20	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
GB0130509D0 (en) *	2001-12-20	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
GB0130511D0 (en) *	2001-12-20	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
US8268352B2 (en)	2002-08-05	2012-09-18	Torrent Pharmaceuticals Limited	Modified release composition for highly soluble drugs
US8216609B2 (en)	2002-08-05	2012-07-10	Torrent Pharmaceuticals Limited	Modified release composition of highly soluble drugs
US7232828B2 (en)	2002-08-10	2007-06-19	Bethesda Pharmaceuticals, Inc.	PPAR Ligands that do not cause fluid retention, edema or congestive heart failure
WO2004062667A1 (fr) *	2003-01-08	2004-07-29	Dr. Reddy's Laboratories Limited	Forme amorphe du maleate de rosiglitazone et procede de preparation
GB0307259D0 (en) *	2003-03-28	2003-05-07	Glaxo Group Ltd	Process
GB2405403A (en) *	2003-08-29	2005-03-02	Cipla Ltd	Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base
WO2005058813A2 (fr) *	2003-12-17	2005-06-30	Ranbaxy Laboratories Limited	Agents antidiabetiques
WO2005065654A2 (fr) *	2003-12-31	2005-07-21	Alpharma, Inc.	Preparations de rosiglitazone
EP1709038A2 (fr) *	2004-01-28	2006-10-11	Usv Limited	Procede de preparation de maleate de 5- 4- 2- n-methyl-n-(2-pyridyl) amino¨ ethoxy¨ phenyl methyl¨ thiazolidine-2, 4-dione
AR047541A1 (es) *	2004-02-13	2006-01-25	Sandoz Ag	Fosfato de 5-[[4-[2-metil-2-piridinil-amino-etoxi]fenil]metil]-2,4 tiazolidinadiona (rosiglitazona) y sus formas polimorficas
GB2410948A (en) *	2004-02-13	2005-08-17	Sandoz Ag	Novel phosphoric acid salt of rosiglitazone
GB2421240A (en) *	2004-12-14	2006-06-21	Sandoz Ag	Phosphoric acid salt of rosiglitazone
CZ296468B6 (cs) *	2004-06-10	2006-03-15	Zentiva, A. S.	Sul kyseliny fosforecné s 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidin-2,4-dionema zpusob její prípravy
CZ296472B6 (cs) *	2004-07-27	2006-03-15	Zentiva, A. S	Sul kyseliny stavelové s 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidin-2,4-dionu azpusob její prípravy a její pouzití
CZ298424B6 (cs) *	2005-05-24	2007-09-26	Zentiva, A. S.	Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel
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KR100749219B1 (ko) *	2006-03-15	2007-08-13	건일제약 주식회사	신규한 로지글리타존 옥살산염, 이의 제조방법, 및 이를포함하는 약제학적 조성물
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1992
- 1992-09-05 GB GB929218830A patent/GB9218830D0/en active Pending
1993
- 1993-09-01 KR KR1020027006870A patent/KR20030097596A/ko not_active Application Discontinuation
- 1993-09-01 SG SG1996008773A patent/SG48302A1/en unknown
- 1993-09-01 JP JP6506983A patent/JP2828777B2/ja not_active Expired - Lifetime
- 1993-09-01 DE DE2001199002 patent/DE10199002I2/de active Active
- 1993-09-01 CA CA002143849A patent/CA2143849C/fr not_active Expired - Lifetime
- 1993-09-01 HU HU9500659A patent/HU224212B1/hu active Protection Beyond IP Right Term
- 1993-09-01 NZ NZ255505A patent/NZ255505A/xx not_active IP Right Cessation
- 1993-09-01 CZ CZ1995565A patent/CZ287473B6/cs not_active IP Right Cessation
- 1993-09-01 ES ES93919489T patent/ES2133410T3/es not_active Expired - Lifetime
- 1993-09-01 KR KR1020087020116A patent/KR20080081099A/ko not_active Application Discontinuation
- 1993-09-01 RU RU95108329A patent/RU2128179C1/ru active
- 1993-09-01 DK DK93919489T patent/DK0658161T3/da active
- 1993-09-01 SK SK277-95A patent/SK280777B6/sk not_active IP Right Cessation
- 1993-09-01 EP EP99108192A patent/EP0960883A1/fr not_active Ceased
- 1993-09-01 AU AU49730/93A patent/AU674880B2/en not_active Expired
- 1993-09-01 AT AT93919489T patent/ATE182147T1/de active
- 1993-09-01 DE DE69325658T patent/DE69325658T2/de not_active Expired - Lifetime
- 1993-09-01 KR KR1019950700873A patent/KR100371297B1/ko not_active IP Right Cessation
- 1993-09-01 HU HU0500355A patent/HU0500355D0/hu not_active Application Discontinuation
- 1993-09-01 WO PCT/GB1993/001853 patent/WO1994005659A1/fr active Application Filing
- 1993-09-01 CA CA002273147A patent/CA2273147A1/fr not_active Abandoned
- 1993-09-01 EP EP93919489A patent/EP0658161B1/fr not_active Expired - Lifetime
- 1993-09-01 SG SG9904980A patent/SG83747A1/en unknown
- 1993-09-01 UA UA95038295A patent/UA41901C2/uk unknown
- 1993-09-01 PL PL93307812A patent/PL173725B1/pl unknown
- 1993-09-02 SI SI9300452A patent/SI9300452B/sl unknown
- 1993-09-02 AP APAP/P/1993/000562A patent/AP513A/en active
- 1993-09-03 MX MX9305397A patent/MX9305397A/es unknown
- 1993-09-03 IL IL106904A patent/IL106904A/xx not_active IP Right Cessation
- 1993-09-03 MY MYPI93001778A patent/MY111190A/en unknown
- 1993-09-03 MA MA23279A patent/MA22970A1/fr unknown
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- 1993-09-04 CN CN93119067A patent/CN1040323C/zh not_active Expired - Lifetime
- 1993-10-07 TW TW082108297A patent/TW385309B/zh not_active IP Right Cessation
- 1993-10-10 SA SA93140245A patent/SA93140245B1/ar unknown
1995
- 1995-03-03 NO NO950852A patent/NO303016B1/no not_active IP Right Cessation
- 1995-03-03 FI FI951004A patent/FI106263B/fi not_active IP Right Cessation
1997
- 1997-05-14 BR BR1100916-0A patent/BR1100916A/pt active IP Right Grant
- 1997-07-14 US US08/892,045 patent/US5910592A/en not_active Ceased
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- 1997-10-30 CN CN97122520A patent/CN1066939C/zh not_active Expired - Lifetime
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- 1997-12-08 CZ CZ19973958A patent/CZ290591B6/cs not_active IP Right Cessation
1998
- 1998-06-02 JP JP10152828A patent/JPH11147885A/ja active Pending
- 1998-09-24 RU RU98117628/04A patent/RU98117628A/ru not_active Application Discontinuation
- 1998-09-24 RU RU98117673/14A patent/RU98117673A/ru not_active Application Discontinuation
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1999
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2001
- 2001-01-05 NL NL300035C patent/NL300035I2/nl unknown
- 2001-01-10 LU LU90712C patent/LU90712I2/fr unknown
- 2001-04-10 NO NO2001005C patent/NO2001005I2/no unknown
- 2001-04-10 NO NO2001006C patent/NO2001006I1/no unknown
- 2001-08-06 JP JP2001238154A patent/JP2002047288A/ja active Pending
2004
- 2004-05-12 JP JP2004142553A patent/JP2004359676A/ja active Pending
2008
- 2008-05-13 JP JP2008125985A patent/JP2008208142A/ja active Pending

Also Published As

Publication number	Publication date
CZ56595A3 (en)	1995-11-15
SK27795A3 (en)	1995-08-09
KR950702982A (ko)	1995-08-23
UA41901C2 (uk)	2001-10-15
DE69325658T2 (de)	1999-12-30
DE10199002I2 (de)	2001-12-13
RU98117628A (ru)	2000-08-20
NO303016B1 (no)	1998-05-18
CZ287473B6 (en)	2000-12-13
CY2138B1 (en)	2002-06-21
JP2002047288A (ja)	2002-02-12
BR1100916A (pt)	2000-07-04
JP2008208142A (ja)	2008-09-11
FI951004A (fi)	1995-03-03
DK0658161T3 (da)	1999-11-29
SI9300452A (en)	1994-06-30
HU0500355D0 (en)	2005-05-30
ES2133410T3 (es)	1999-09-16
FI951004A0 (fi)	1995-03-03
AP9300562A0 (en)	1993-10-31
NO974646D0 (no)	1997-10-08
HUT72639A (en)	1996-05-28
JP2004359676A (ja)	2004-12-24
GB9218830D0 (en)	1992-10-21
SI9300452B (sl)	2003-02-28
CN1101911A (zh)	1995-04-26
ZA936509B (en)	1994-06-16
SA93140245B1 (ar)	2005-10-15
JPH08501095A (ja)	1996-02-06
CA2143849A1 (fr)	1994-03-17
NO2001006I1 (no)	2001-04-30
NO2001005I2 (no)	2004-06-01
NO950852L (no)	1995-03-03
EP0960883A1 (fr)	1999-12-01
EP0658161A1 (fr)	1995-06-21
NL300035I1 (nl)	2001-03-01
IL106904A0 (en)	1993-12-28
WO1994005659A1 (fr)	1994-03-17
HU9500659D0 (en)	1995-04-28
FI982413A0 (fi)	1998-11-06
AU674880B2 (en)	1997-01-16
MY111190A (en)	1999-09-30
PL307812A1 (en)	1995-06-26
NL300035I2 (nl)	2001-07-02
RU95108329A (ru)	1996-12-20
RU2128179C1 (ru)	1999-03-27
CA2273147A1 (fr)	1994-03-17
KR20080081099A (ko)	2008-09-05
JP2828777B2 (ja)	1998-11-25
CN1063942C (zh)	2001-04-04
TW385309B (en)	2000-03-21
KR100371297B1 (ko)	2003-05-09
PL173725B1 (pl)	1998-04-30
NZ255505A (en)	1997-08-22
NO974646L (no)	1995-03-03
EP0658161B1 (fr)	1999-07-14
FI982413A (fi)	1998-11-06
MX9305397A (es)	1995-01-31
SG48302A1 (en)	1998-04-17
AP513A (en)	1996-07-30
DE69325658D1 (de)	1999-08-19
CN1183276A (zh)	1998-06-03
HU224212B1 (hu)	2005-06-28
FI106263B (fi)	2000-12-29
HK1012363A1 (en)	1999-07-30
KR20030097596A (ko)	2003-12-31
SK280777B6 (sk)	2000-07-11
AU4973093A (en)	1994-03-29
GR3030794T3 (en)	1999-11-30
NO305802B1 (no)	1999-07-26
CN1040323C (zh)	1998-10-21
ATE182147T1 (de)	1999-07-15
CA2143849C (fr)	2000-04-25
CN1051312C (zh)	2000-04-12
JPH11147885A (ja)	1999-06-02
IL106904A (en)	1997-09-30
MA22970A1 (fr)	1994-04-01
CZ290591B6 (cs)	2002-08-14
CN1183275A (zh)	1998-06-03
US5910592A (en)	1999-06-08
SG83747A1 (en)	2001-10-16
RU98117673A (ru)	2000-07-20
CN1066939C (zh)	2001-06-13
CN1183413A (zh)	1998-06-03
NO950852D0 (no)	1995-03-03

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FI933804A0 (fi)	1993-08-31	Monohydrat av 5-(2-(4-(1,2-bensisotiazol-3-yl)-1-piperazinyl)etyl-6-klor-1,3-dihydro-2h-indol-2-onkhydroklorid
LU91131I2 (fr)	2005-03-29	Duloxétine et ses sels d'addition acides pharmaceutiquement acceptables, et en particulier, chlorhydrate de duloxétine.
LU91452I2 (fr)	2008-08-04	"Mycafungine et ses sels pharmaceutiquement acceptables(MYCAMINEr)"
LU91291I2 (fr)	2007-01-29	Deferasirox et ses sels pharmaceutiquement acceptables (EXJADEr)
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ITGE940106A0 (it)	1994-09-21	Dispositivo per l'agugliatura di una falda di ovatta.
NO980211D0 (no)	1998-01-16	Opplösning av 1-azabicyklo£2.2.2\|oktan-3-amin,2-(difenylmetyl)-N-££2-metoksy-5-(1-metyletyl)fenyl\|metyl\|
FR2693368B1 (fr)	1994-09-30	Trépan perfectionné notamment pour chirurgie oculaire.
IT1243053B (it)	1994-05-23	Procedimento di metallizzazione impiegante uno strato di nitruro di titanio amorfo.
FR2686766B1 (fr)	1996-06-14	Charrue reversible semi-portee.
FR2704154B1 (fr)	1995-07-13	Mur d'entrainement concave.